Lozano F, Pujol E, Torres-Cisneros J, Bascunana A, Canas E, Garcia-Ordonez MA, Hernandez-Quero J, Vergara A, Marquez M, Diez F; International Conference on AIDS.
Int Conf AIDS. 1994 Aug 7-12; 10: 197 (abstract no. PB0803).
Hospital General de Huelva, Spain.
OBJECTIVE: HIV-associated FUO is an entity with peculiar significance and not yet adequately studied till now. Our purpose was to document the occurrence, etiology, prognosis and profitability diagnosis of FUO. METHODS: A prospective 2-year (92-93) study was realized with 116 in-patients from 14 hospitals of Andalusia. They fullfilled following criterion: 1) Proved HIV infection, 2) Fever > 38.3 degrees C, more of three weeks of duration, 3) Not etiologic diagnosis after one week hospitalization, 4) Not evidence of clinical or radiologic data of focal point infection at admission moment. RESULTS: Frecuency of HIV-associated FUO was 3.1%. The average patient's age was 31.2 + 8.4 years. 88% of them were males, 82% intravenous drug abusers and 40% were AIDS diagnosis previously. Mean duration of fever and hospitalization was 68 + 38.3 days and 40.1 + 25.3 respectively. Mean number of CD4 lymphocites was 98.7 + 145/mm3 (76% had < 100/mm3 and 59% had < 50/mm3). A sure diagnosis was achieved in 75% of patients. Most common entities were: tuberculosis (37%), visceral leishmaniasis (19%), MAI infection (8%) and lymphomas (7%). Diagnosis was probably suspected in 19% of patients (tuberculosis was suspected in 65% of them) and in a 6% any etiologic diagnosis was obtained. The most valuable investigations was hepatic biopsy (67%) and bone marrow puncture (38%). During hospitalization period 10% of patients died. DISCUSSION AND CONCLUSIONS: 1) HIV-associated FUO is a relatively common entity that appears in advanced HIV-infection and bears a high economic cost. 2) More prevalent etiologies in our country are tuberculosis and visceral leishmaniasis.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Biomedical Research
- Communicable Diseases
- Fever
- Fever of Unknown Origin
- HIV
- HIV Infections
- HIV Seropositivity
- Hospitalization
- Humans
- Leishmaniasis, Visceral
- Male
- Population Groups
- Prospective Studies
- Tuberculosis
Other ID:
UI: 102210256
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