Bibliographic Citation
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Title | Resistance to infection with Eimeria vermiformis in mouse radiation chimeras is determined by donor bone-marrow cells |
Creator/Author | Joysey, H.S. ; Wakelin, D. ; Rose, M.E. |
Publication Date | 1988 May 01 |
OSTI Identifier | OSTI ID: 7025079 |
Other Number(s) | CODEN: INFIB |
Resource Type | Journal Article |
Resource Relation | Infect. Immun. ; Vol/Issue: 56:5 |
Research Org | Institute for Animal Health, Huntingdon (England) |
Subject | 560152 -- Radiation Effects on Animals-- Animals; BONE MARROW CELLS-- GENOTYPE;PARASITES-- INFECTIVITY; IMMUNITY;LYMPHOCYTES;MICE;PHENOTYPE;RADIATION CHIMERAS |
Related Subject | ANIMAL CELLS;ANIMALS;BIOLOGICAL MATERIALS;BLOOD;BLOOD CELLS;BODY FLUIDS;CHIMERAS;CONNECTIVE TISSUE CELLS;LEUKOCYTES;MAMMALS;MATERIALS;MOSAICISM;RODENTS;SOMATIC CELLS;VERTEBRATES |
Description/Abstract | The course of infection with Eimeria vermiformis was determined in BALB/b, BALB/c, and C57BL/10ScSn (B10) mice and in radiation chimeras prepared from the H-2-compatible BALB/b and B10 mice.^The BALB strains, irrespective of H-2 haplotype, were resistant, the B10 mice were susceptible, and in the chimeras infection was characterized by the genotype of the donated bone-marrow cells and not by the phenotype of the recipient.^Thus, the genetic control of relative resistance or susceptibility to infection with this parasite is expressed through bone-marrow-derived cells. |
Country of Publication | United States |
Language | English |
Format | Pages: 1399-1401 |
System Entry Date | 2001 May 13 |
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