#gi CAI CAI_Alm CBI COG COGanno COGfun Annotation 247966 1.2713785462877 2.91630266650917 1.00695405494459 747 ABC-type dipeptide transport system, periplasmic component E Dipeptide ABC transporter, binding protein 247967 1.2573690724221 2.91825913725012 1.02268145876021 747 ABC-type dipeptide transport system, periplasmic component E Dipeptide ABC transporter, binding protein 247968 1.50403143508571 3.3352563733416 1.01611751571257 - - - hypothetical protein 247969 1.32784976602999 3.1982322823201 1.04740049843176 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Dipeptide ABC transporter, permease protein 247970 1.35195156787815 3.40438303606768 1.14984986881849 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Dipeptide ABC transporter, permease protein 247971 1.30220749445902 2.93728366402114 1.01125682780301 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP Dipeptide ABC transporter, ATP-binding protein 247972 1.30779205487026 2.98768774159555 0.97587187150978 1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP Dipeptide ABC transporter, ATP-binding protein 247973 1.40917145061236 3.53116309028457 1.19261760941135 1808 Predicted membrane protein S conserved protein 247974 1.36418345741303 3.39955325795882 1.16387055112442 1808 Predicted membrane protein S conserved protein 247975 1.43563511538851 3.70106291209402 1.17299013911511 - - - hypothetical protein 247976 1.25586795816472 2.82332813473809 0.994387341184922 - - - conserved protein 247977 1.22871426601479 2.67904122633229 0.938259603803364 5507 Uncharacterized conserved protein S RNA signal recognition particle 4.5S RNA 247978 1.26482251903957 2.81968144331353 0.948231763372287 - - - conserved protein 247979 1.35254711164263 3.05164267208928 0.96079780158823 20 Undecaprenyl pyrophosphate synthase I Undecaprenyl pyrophosphate synthetase 247980 1.42909116178192 3.21427737506969 0.985373661771815 2230 Cyclopropane fatty acid synthase and related methyltransferases M methyltransferase 247981 1.2703220610798 2.84157390246475 1.07293865037223 361 Translation initiation factor 1 (IF-1) J translation initiation factor 1A 247982 1.36744027108526 3.08870156720696 1.0682239788064 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H Ubiquinone/menaquinone biosynthesis methyltransferase 247983 1.57838821676685 3.49111562855242 1.04396046864657 - - - conserved protein 247984 1.34544798863633 3.0396509343311 1.04332346434286 1373 Predicted ATPase (AAA+ superfamily) R conserved protein 247985 1.42293960508166 3.18993057017265 0.943897846133887 - - - conserved protein 247986 1.34472803542276 2.8350622147133 0.927615229008387 - - - conserved protein 247987 1.27838711992134 2.8904189163634 0.982744443777624 1598 Uncharacterized conserved protein S hypothetical protein 247988 1.34570383735759 3.17240674811312 1.09517144093816 1724 Predicted periplasmic or secreted lipoprotein N conserved protein 247989 1.33543745896552 2.76110341503631 0.934962692911579 - - - hypothetical protein 247990 1.3203769006571 3.06732879888917 1.0105692014244 - - - hypothetical protein 247991 1.37952632172733 3.01064895409658 0.996198869176754 - - - conserved protein 247992 1.28528238808371 2.68572535164491 0.903817946036471 - - - conserved protein 247993 1.34440889759546 2.93965355706359 0.952053284596969 1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) L Superfamily I DNA and RNA helicase 247994 1.27926545708051 3.09302225541536 0.977428922260938 - - - conserved protein 247995 1.3729984342511 3.00534827134987 0.887260313663114 3063 Tfp pilus assembly protein PilF NU O-linked N-acetylglucosamine transferase 247996 1.26730646801623 2.86536568688928 0.977217553599274 1598 Uncharacterized conserved protein S hypothetical protein 247997 1.49125489699439 3.54184431067364 1.10463744430859 1724 Predicted periplasmic or secreted lipoprotein N conserved protein 247998 1.25450703465496 2.65309172972831 0.920695672260672 - - - conserved protein 247999 1.45250620749761 3.2353651264382 0.903171798176977 - - - hypothetical protein 248000 1.35915754899885 3.0496208873245 0.908660829179987 - - - conserved protein 248001 1.45877579001835 3.26908428398039 0.982026202442556 - - - hypothetical protein 248002 1.33915750296225 2.99345448627587 0.979823367246254 137 Argininosuccinate synthase E Argininosuccinate synthase 248003 1.31486024079025 3.00723026506668 1.02966616177762 458 Carbamoylphosphate synthase large subunit (split gene in MJ) EF Carbamoyl-phosphate synthase large chain 248004 1.29193673491312 2.9437649461216 1.03449923936065 505 Carbamoylphosphate synthase small subunit EF Carbamoyl-phosphate synthase small chain 248005 1.29028504291077 2.98281092606576 1.03311726606381 4175 ABC-type proline/glycine betaine transport system, ATPase component E Glycine betaine transporter, ATP-binding protein 248006 1.35745457705517 3.31408135226582 1.11144323722328 4176 ABC-type proline/glycine betaine transport system, permease component E Glycine betaine transporter, permease protein 248007 1.24481296520027 2.78455360494411 1.00085544032871 2113 ABC-type proline/glycine betaine transport systems, periplasmic components E Glycine betaine transporter, substrate-binding protein 248008 1.27299629108218 3.20381924409983 1.07684150441486 3391 Uncharacterized conserved protein S conserved protein 248009 1.2564997509711 2.71197348370601 0.944070573209407 3063 Tfp pilus assembly protein PilF NU hypothetical protein 248010 1.31589212909895 2.98270285749456 1.00350080222944 666 FOG: Ankyrin repeat R hypothetical protein 248011 1.2429524813708 3.21028366018028 1.06199870022049 - - - hypothetical protein 248012 1.288427859414 2.9225930502051 1.02055095784546 160 4-aminobutyrate aminotransferase and related aminotransferases E Acetylornithine aminotransferase 248013 1.33600438944614 3.11887233497254 1.09963438998222 1012 NAD-dependent aldehyde dehydrogenases C Aldehyde dehydrogenase 248014 1.25266877660283 2.83965215221363 0.97178632114869 2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains T conserved protein 248015 1.28909568971305 2.88486195280304 1.02113923958384 2511 Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) J Glutamyl-tRNA(Gln) amidotransferase 248016 1.252596768543 2.79587693172242 0.956491492300553 - - - hypothetical protein 248017 1.35117523854173 3.06505477904006 0.928487663413068 3547 Transposase and inactivated derivatives L Transposase 248018 1.39140467835153 3.2154213953983 1.03114774354844 - - - hypothetical protein 248019 1.27557786574844 3.07713679677351 1.06959840200337 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 248020 1.30459851210775 2.7816425325202 0.976932406573305 1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) C tungsten formylmethanofuran dehydrogenase subunit F 248021 1.29999177731603 2.96799241125688 1.0504880931083 1148 Heterodisulfide reductase, subunit A and related polyferredoxins C Heterodisulfate reductase, subunit A 248022 1.22787860970931 2.562279701922 0.93061346725271 4802 Ferredoxin-thioredoxin reductase, catalytic subunit C Ferredoxin-thioredoxin reductase, catalytic chain 248023 1.30313044697021 2.89158039069 1.02686399570507 1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) C tungsten formylmethanofuran dehydrogenase subunit G 248024 1.27836052189973 2.94135825289613 1.02495751954553 1029 Formylmethanofuran dehydrogenase subunit B C tungsten formylmethanofuran dehydrogenase subunit B 248025 1.32021817237012 3.05210168926689 1.01244209372104 1153 Formylmethanofuran dehydrogenase subunit D C tungsten formylmethanofuran dehydrogenase subunit D 248026 1.28255400400903 3.00423499440229 1.00427083698099 - - - conserved protein 248027 1.29363537429912 2.96070539828135 1.04010483868644 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H SAM-dependent methyltransferases 248028 1.27458746650725 3.02371736227352 1.06532560295228 3420 Nitrous oxidase accessory protein P surface layer protein B 248029 1.31390239940286 3.25227668510914 1.12177024516464 3420 Nitrous oxidase accessory protein P surface layer protein B 248030 1.36361961650978 3.20726816034925 1.05977153386217 - - - hypothetical protein 248031 1.27053503830892 3.08519041338741 1.09157401743403 3291 FOG: PKD repeat R conserved protein 248032 1.27253853500986 2.79470638855872 0.994797853032778 123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein BQ hypothetical protein 248033 1.32849414166052 3.17375942392999 1.10065241330342 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ N-methylhydantoinase (ATP-hydrolyzing) 248034 1.35533341356921 3.35390963449787 1.14019252673188 385 Predicted Na+-dependent transporter R Sodium-dependent transporter 248035 1.27207668580717 2.91213843362952 1.01020735456857 1189 Predicted rRNA methylase J putative ribosomal RNA methyltransferase 248036 1.26380915415591 2.82652399137812 0.983644142029408 4073 Uncharacterized protein conserved in archaea S conserved protein 248037 1.31252891744835 3.02745748736848 1.0753989416393 459 Chaperonin GroEL (HSP60 family) O Thermosome subunit 248038 1.28486255483304 3.0937120903138 1.05329968551798 120 Ribose 5-phosphate isomerase G Ribose 5-phosphate isomerase 248039 1.30426912906442 2.98917665278308 1.04626288528138 17 Aspartyl/asparaginyl-tRNA synthetases J Aspartyl-tRNA synthetase 248040 1.29511550324913 2.99104247373075 0.957015219678076 3794 Plastocyanin C conserved protein 248041 1.31894762102397 2.85292676681974 0.973306551505532 - - - hypothetical protein 248042 1.19996756368712 2.72207084079827 0.919124331467231 1409 Predicted phosphohydrolases R hypothetical protein 248043 1.31103435595571 2.98002095218563 0.992642778285706 2236 Predicted phosphoribosyltransferases R Xanthine-guanine phosphoribosyltransferase 248044 1.37730022740886 3.12882202186964 1.04352030325135 - - - conserved protein 248045 1.26911060271428 2.88332261127132 1.00933966084213 - - - hypothetical protein 248046 1.29850968109815 3.15137002934978 1.10291423454955 2848 Uncharacterized conserved protein S hypothetical cytosolic protein 248047 1.24124950314383 2.90359421279019 1.01901025754664 3830 ACT domain-containing protein T Phosphoserine phosphatase 248048 1.24332559589428 2.94675206570962 0.903641836449041 - - - hypothetical protein 248049 1.34514380770291 3.20079065222612 1.07291812720035 703 Shikimate kinase E Shikimate kinase 248050 1.22086299310083 2.9375294201403 1.02926939484583 - - - conserved protein 248051 1.27896949698521 2.91959452631378 1.01020034691973 1303 Uncharacterized protein conserved in archaea S hypothetical protein 248052 1.27773647656871 2.96272099835137 1.05018764828657 213 Thymidine phosphorylase F Pyrimidine-nucleoside phosphorylase 248053 1.33117366423899 3.29215069544133 1.12861095054104 5006 Predicted permease, DMT superfamily R Transporter 248054 1.3646866448065 3.32305490264242 1.14068742843175 - - - hypothetical protein 248055 1.27103201397419 2.84428240273972 0.998483404772937 - - - conserved protein 248056 1.31920543900978 3.23437193420914 1.12028755789349 4591 ABC-type transport system, involved in lipoprotein release, permease component M ABC transporter permease protein 248057 1.287878394159 3.09136157092562 1.07944919487825 - - - conserved protein 248058 1.26597433164716 2.88315919003494 1.02191690344016 1492 Cobyric acid synthase H Cobyric acid synthase 248059 1.61912866530597 3.88989110763562 1.15878994476144 - - - hypothetical protein 248060 1.27494644837887 2.87406571086916 0.956601717537595 - - - conserved protein 248061 1.35234764711688 3.06861330527871 0.918056354821411 3547 Transposase and inactivated derivatives L Transposase 248062 1.27297809560717 2.93477436266276 1.01623939653313 2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog E Ornithine cyclodeaminase 248063 1.35208756589053 3.17349329086017 1.06840017164671 2454 Uncharacterized conserved protein S conserved protein 248064 1.26450014390942 2.74474691745482 0.943760930622838 5010 Flp pilus assembly protein TadD, contains TPR repeats U O-linked N-acetylglucosamine transferase 248065 1.31185181204408 3.02685853069256 1.01159884895825 - - - conserved protein 248066 1.31924247279622 2.93563052708635 1.03995098765415 - - - conserved protein 248067 1.29232358924699 2.95998448281086 1.03628178143121 639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases T Serine/threonine protein phosphatase 248068 1.29328985744883 2.84784844683534 0.989328131083943 3063 Tfp pilus assembly protein PilF NU O-linked N-acetylglucosamine transferase 248069 1.5334521191162 3.48208030549496 1.00586627497133 - - - hypothetical protein 248070 1.29825847869817 3.4298514684589 1.16534103717196 - - - hypothetical protein 248071 1.28661789560135 3.00162226394861 1.06204086660593 3030 Protein affecting phage T7 exclusion by the F plasmid R FxsA protein 248072 1.35288568568065 3.42975107986371 1.15254865136382 1346 Putative effector of murein hydrolase M hypothetical protein 248073 1.37373442558976 3.3503112724169 1.13860574299493 1380 Putative effector of murein hydrolase LrgA R hypothetical protein 248074 1.32533568555767 3.0463929041857 1.05707811284876 1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes E Cysteine desulfhydrase 248075 1.28515620067795 2.77701648797224 0.93619395301357 822 NifU homolog involved in Fe-S cluster formation C NifU protein 248076 1.28380188970424 2.96359274482221 1.01922542802937 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ Ribosomal protein S6 modification protein 248077 1.34475156876622 2.97736108043185 1.00609889417367 1990 Uncharacterized conserved protein S hypothetical protein 248078 1.32187290621937 3.1425000881784 1.09339753669262 1305 Transglutaminase-like enzymes, putative cysteine proteases E conserved protein 248079 1.31249206183989 2.97066240320491 1.03249185090992 585 Uncharacterized conserved protein S conserved protein 248080 1.41675278824651 3.48334515440586 1.16680275670688 534 Na+-driven multidrug efflux pump V putative transmembrane efflux protein 248081 1.33527184009903 2.91175335215854 0.991022804601905 1846 Transcriptional regulators K transcriptional regulator, MarR family 248082 1.30671403438223 3.11912921729955 1.07102375464353 - - - hypothetical protein 248083 1.27286143485659 2.87227090540952 0.994008668048901 504 CTP synthase (UTP-ammonia lyase) F CTP synthase 248084 1.30850008229316 3.00944191955365 1.04875451025783 - - - hypothetical protein 248085 1.30113339361076 2.90334363277948 1.08097519422047 2835 Uncharacterized conserved protein S conserved protein 248086 1.34421378000325 3.11277905217815 1.08188053602378 1151 6Fe-6S prismane cluster-containing protein C Carbon monoxide dehydrogenase 248087 1.28138460951314 2.98625559250184 1.02793483459651 437 Fe-S-cluster-containing hydrogenase components 1 C Iron-sulfur protein 248088 1.30821544014441 3.03799534305024 1.05827195403865 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 248089 1.3104361062482 3.22665174369535 1.10174817119216 3366 Uncharacterized protein conserved in archaea S conserved protein 248090 1.27485234699084 2.91267441752321 1.01950178427179 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 248091 1.27148724863075 3.05709492255034 1.07219665616768 312 Predicted Zn-dependent proteases and their inactivated homologs R PmbA protein 248092 1.288239565471 2.98758597540613 1.03559340189265 312 Predicted Zn-dependent proteases and their inactivated homologs R Zinc metalloprotease 248093 1.29353255063091 2.97412562359354 1.04103247899928 1067 Predicted ATP-dependent protease O ATP-dependent protease La 248094 1.31434546192765 2.81786732076134 0.96280643518619 - - - conserved protein 248095 1.2427882305652 2.90434250603624 1.07475787710149 - - - conserved protein 248096 1.2840467343355 2.70297594046875 0.922653725370401 - - - conserved protein 248097 1.27348934323807 2.83609691979154 1.00901788116248 - - - conserved protein 248098 1.2905285186632 3.00483649275252 1.071417562823 498 Threonine synthase E Threonine synthase 248099 1.27874596057246 2.92784352259048 1.01384695857152 4032 Predicted thiamine-pyrophosphate-binding protein R Sulfopyruvate decarboxylase alpha chain 248100 1.27449385312109 2.97162960912537 1.06444207506099 1900 Uncharacterized conserved protein S Ferredoxin oxidoreductase 248101 1.30219926113693 3.05851013832861 1.01794455595919 491 Zn-dependent hydrolases, including glyoxylases R Zn-dependent hydrolase 248102 1.36569104292799 3.19702623655624 1.06152623973581 - - - conserved protein 248103 1.32363182234118 3.06474147073235 1.03898483275436 4738 Predicted transcriptional regulator K conserved protein 248104 1.35563388200527 3.30579377646907 1.15137790119504 1138 Cytochrome c biogenesis factor O Cytochrome c-type biogenesis protein 248105 1.33396137508331 3.27283422277788 1.07516821279615 1138 Cytochrome c biogenesis factor O putative cytochrome c biogenesis factors 248106 1.34413897399671 3.26326611466578 1.09280608037019 575 CDP-diglyceride synthetase I conserved protein 248107 1.27591420273695 2.98635559322392 1.0314556620256 461 Orotate phosphoribosyltransferase F Orotate phosphoribosyltransferase 248108 1.41465175002136 3.05784939859298 0.976953424372736 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S 4-carboxymuconolactone decarboxylase 248109 1.27788939653043 2.84261577572215 1.00883497363746 151 Phosphoribosylamine-glycine ligase F Phosphoribosylamine--glycine ligase 248110 1.31892093576391 3.03324761524543 1.03812763705569 78 Ornithine carbamoyltransferase E Ornithine carbamoyltransferase 248111 1.42021104399808 3.28892855197896 0.9822970178417 1378 Predicted transcriptional regulators K transcriptional regulator 248112 1.34783952627057 2.98420394260156 0.952430265070266 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 248113 1.44116239830636 3.37200691401025 1.08981872055104 - - - conserved protein 248114 1.42992438664086 3.20964829683921 0.991869780754949 3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoi M hypothetical protein 248115 1.46667877636424 3.39894265190174 1.06382235049745 702 Predicted nucleoside-diphosphate-sugar epimerases MG putative nucleoside-diphosphate-sugar epimerase 248116 1.28399070736147 2.85841669478144 0.906105429416473 3378 Predicted ATPase R conserved protein 248117 1.34942927571216 2.9759854191157 0.990562014209311 4974 Site-specific recombinase XerD L DNA integration/recombination/invertion protein 248118 1.3175520851464 2.90058264307807 0.979987259910531 - - - conserved protein 248119 1.2744267230362 2.78153281831558 0.996657731195455 - - - conserved protein 248120 1.26862250566091 2.70165214445525 0.936480093230677 - - - conserved protein 248121 1.32966992916624 2.9411789770286 1.04480234057238 1002 Type II restriction enzyme, methylase subunits V type IIS restriction enzyme 248122 1.50322354952931 3.43612064445918 1.05163421051658 2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared wi K ATP-dependent DNA helicase 248123 1.41530860803775 3.15660694222294 1.0159592028952 - - - ATP-dependent DNA helicase 248124 1.30512430675481 2.80787931755396 0.933651365052266 - - - hypothetical protein 248125 1.38410247296719 3.168953992748 1.06554739284397 1724 Predicted periplasmic or secreted lipoprotein N hypothetical protein 248126 1.23675990584676 2.83995419348105 1.15937168243519 - - - hypothetical protein 248127 1.34895490311071 2.98377399518014 1.01677978015527 1672 Predicted ATPase (AAA+ superfamily) R conserved protein 248128 1.29133016934771 2.79978307984844 0.997076928940947 - - - DNA repair protein 248129 1.29328435007559 2.96086853594501 1.04430211460346 4930 Predicted ATP-dependent Lon-type protease O ATP-dependent protease La 248130 1.40129035703664 3.01577901958703 0.948164867141229 - - - hypothetical protein 248131 1.3585314503609 3.12365720579948 1.07194363420767 5310 Homospermidine synthase Q homospermidine synthase 248132 1.25931806823112 3.06492815715504 1.08440211611172 53 Predicted Co/Zn/Cd cation transporters P Cobalt-zinc-cadmium resistance protein 248133 1.42134249483251 3.20838494713117 1.11248555597393 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 248134 1.43546304313759 3.24471776834826 1.08255101743749 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 248135 1.24858374502245 2.65717174823532 0.885203417947716 - - - Transposase 248136 1.46470876366112 3.39536327527978 1.02962117888917 3415 Transposase and inactivated derivatives L Transposase 248137 1.38921884083459 3.13955085789163 1.07394796689948 2202 FOG: PAS/PAC domain T hypothetical sensory transduction histidine kinase 248138 1.31653931074738 3.02430188306328 1.0457933307346 1865 Uncharacterized conserved protein S Transporter 248139 1.32791347187543 2.96092876658407 1.00274120055811 5012 Predicted cobalamin binding protein R Methanol corrinoid protein 248140 1.26226677395819 2.85520955707761 0.962534829667364 - - - Methanol:corrinoid methyltransferase 248141 1.27357557844001 2.99402066832146 1.07775706089723 407 Uroporphyrinogen-III decarboxylase H Methylcobalamin:coenzyme M methyltransferase 248142 1.24910204578844 2.84906052312917 0.971114792434474 2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 R conserved protein 248143 1.26199977872787 2.70474990865773 0.955243380592976 4783 Putative Zn-dependent protease, contains TPR repeats R conserved protein 248144 1.40631580909873 2.97328772445273 0.980061690113216 - - - conserved protein 248145 1.33016530603293 2.88453093461913 0.9803217287159 456 Acetyltransferases R Diamine acetyltransferase 248146 1.3935015680336 3.15548724791753 1.06723234577746 4866 Uncharacterized conserved protein S conserved protein 248147 1.33156785385767 3.05547451828845 1.05889836578617 422 Thiamine biosynthesis protein ThiC H Thiamine biosynthesis protein 248148 1.26276274733521 2.81136142611802 0.998689789465823 550 Topoisomerase IA L DNA topoisomerase III 248149 1.25598553589371 2.91569823942177 0.918734868897627 1890 Ribosomal protein S3AE J SSU ribosomal protein S3AE 248150 1.35860961516655 3.14865572515235 1.05562355440063 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR Short chain dehydrogenase/reductase 248151 1.52585499792346 3.4626342404604 1.09341766762915 4274 Uncharacterized conserved protein S conserved protein 248152 1.29301222636138 2.9084863635344 0.962623583105717 1669 Predicted nucleotidyltransferases R nucleotidyltransferase 248153 1.4707725528039 3.34969296170537 1.05585609796541 2361 Uncharacterized conserved protein S hypothetical nucleotidyltransferase 248154 1.47601947404854 3.41066228720775 1.07776541260545 4274 Uncharacterized conserved protein S conserved protein 248155 1.36147877328877 3.01397351315167 1.009053435469 210 Superfamily I DNA and RNA helicases L DNA helicase II 248156 1.32613642457535 2.96050549023781 0.996519300705183 5421 Transposase L Transposase 248157 1.33112845266455 2.89834372446678 0.962000874859153 - - - hypothetical protein 248158 1.32114637608013 2.86097451120498 0.981973521177504 2189 Adenine specific DNA methylase Mod L type III restriction-modification system methylation subunit 248159 1.30460621772088 2.78577912115319 0.984431197245186 - - - conserved protein 248160 1.26563414620822 2.80987608058633 0.977968433596239 - - - conserved protein 248161 1.43143578929814 3.07199927297165 0.839132765752675 433 Predicted ATPase R conserved protein 248162 1.36562455599036 3.09510489226232 0.946030262518052 - - - conserved protein 248163 1.33925999015648 2.96319336140297 1.02805192983953 2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared wi K ATP-dependent DNA helicase 248164 1.27022486270578 2.62846574673396 1.05378379837042 - - - conserved protein 248165 1.38828456990495 3.04291804324293 1.00960563830724 - - - conserved protein 248166 1.24730911417208 2.80981862413365 0.955633233445811 - - - conserved protein 248167 1.22343698736057 2.66056455742068 1.0064719016157 - - - hypothetical protein 248168 1.34141223686081 2.91913163592248 0.992651620249587 4804 Uncharacterized conserved protein S hypothetical protein 248169 1.32644157529059 2.85635269599099 0.940770626731642 - - - hypothetical protein 248170 1.33048914454679 3.15827260563329 1.10395468896652 2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared wi K conserved protein 248171 1.31381140770998 2.87502047716198 0.961418702650522 2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared wi K conserved protein 248172 1.34046142344641 3.08080553918293 1.00470248079914 - - - hypothetical protein 248173 1.25271769553577 2.73004872837807 0.961221851845412 - - - hypothetical protein 248174 1.31127404412817 2.8008676634223 0.981053305139724 - - - hypothetical protein 248175 1.35879961268184 2.86168596190095 1.05128895938428 - - - conserved protein 248176 1.24862434248539 2.99700788381208 1.06692109250378 4870 Cysteine protease O Cysteine proteinase 248177 1.31045053399774 3.04144019560544 1.06694470511325 - - - conserved protein 248178 1.33088597346985 3.14715087464297 1.0994954007041 608 Single-stranded DNA-specific exonuclease L putative single-stranded-DNA-specific exonuclease 248179 1.31923412616547 3.38007401161456 1.10786195431847 3391 Uncharacterized conserved protein S hypothetical protein 248180 1.28329817184339 3.118860093301 1.10936723811334 - - - hypothetical protein 248181 1.26330100199186 3.06592582029006 1.07393900046035 - - - conserved protein 248182 1.28427022479007 3.07066812887241 1.02125606564728 - - - conserved protein 248183 1.28636447944648 3.01507574644266 1.07211859036287 - - - conserved protein 248184 1.27973666683579 2.85995422931571 0.980777314085514 - - - conserved protein 248185 1.35811748413436 3.14583259689712 1.0348820751477 - - - conserved protein 248186 1.29173306816364 3.03967989349892 1.06283924334551 1031 Uncharacterized Fe-S oxidoreductase C Fe-S oxidoreductase 248187 1.32544862426737 3.08633027386489 1.03398872157118 1635 Flavoprotein involved in thiazole biosynthesis H thiazole biosynthetic enzyme 248188 1.25034744423083 2.96910226065122 1.02726648065342 3187 Heat shock protein O hypothetical protein 248189 1.37405337529469 3.40812603040088 1.1214185258728 3585 Molybdopterin-binding protein H Molybdenum-pterin-binding-protein 248190 1.29741756762208 2.95227287650598 1.00614778911834 - - - conserved protein 248191 1.27385356529916 2.80745962360765 0.931426234763392 - - - conserved protein 248192 1.31843051691076 2.76301645091556 0.967305679354121 - - - conserved protein 248193 1.33688715937318 2.85825784228431 1.02968202130525 - - - hypothetical protein 248194 1.46434491203015 3.35263633695688 1.09422371342137 - - - hypothetical protein 248195 1.30911225857584 3.19719611277271 1.11188977667665 530 Ca2+/Na+ antiporter P sodium-calcium exchanger 248196 1.2838413194749 3.06169270309195 1.04498064039622 170 Dolichol kinase I hypothetical protein 248197 1.26627436404484 2.7980881928805 0.984398094243311 3324 Predicted enzyme related to lactoylglutathione lyase R hypothetical protein 248198 1.29725993202023 2.89220310825672 1.01973238927516 2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain R Alanyl-tRNA synthetase 248199 1.2956031376399 3.18049135310034 1.11776059876665 - - - conserved protein 248200 1.33116287114274 2.92358707302065 1.02121705783824 - - - conserved protein 248201 1.29270524665853 3.15685378474842 1.07602700833513 668 Small-conductance mechanosensitive channel M putative mechanosensitive ion channel 248202 1.28869822645938 2.87089623239528 0.997549829147922 1504 Uncharacterized conserved protein S conserved protein 248203 1.29099894979548 3.00353617721008 1.02302040799778 2013 Uncharacterized conserved protein S hypothetical protein 248204 1.27698171493599 2.8689387510331 1.00202763843786 1810 Uncharacterized protein conserved in archaea S conserved protein 248205 1.22725170012155 2.74750135525941 1.00317375564861 1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain C Ferredoxin 248206 1.26699072327721 3.00448192315403 1.06228587636392 1900 Uncharacterized conserved protein S hypothetical protein 248207 1.37758278880477 3.13340628238964 1.04633785221714 615 Cytidylyltransferase MI Glycerol-3-phosphate cytidylyltransferase 248208 1.27253477546108 2.92738007199565 1.01554916726454 436 Aspartate/tyrosine/aromatic aminotransferase E Aspartate aminotransferase 248209 1.33662418835243 3.06336660454219 1.06782336150287 54 Riboflavin synthase beta-chain H Riboflavin synthase, subunit beta 248210 1.31170228498057 2.85345435336701 0.96784134617417 1731 Archaeal riboflavin synthase H Riboflavin synthase, subunit alpha 248211 1.27021169228355 2.91100676626894 1.0352458921485 75 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase E Serine-pyruvate aminotransferase 248212 1.2619176885791 3.06673850306702 1.04846361656003 3620 Predicted transcriptional regulator with C-terminal CBS domains K putative inosine monophosphate dehydrogenase 248213 1.36993599050298 3.15588786175933 1.09467179536833 464 ATPases of the AAA+ class O Cell division cycle protein 248214 1.30230326665103 3.02944604745416 1.01726776274549 655 Multimeric flavodoxin WrbA R BRAMP 248215 1.33008932748385 2.82143631562288 0.897213770224933 3436 Transposase and inactivated derivatives L Transposase 248216 1.50540224392845 3.47153693300709 0.965872307925411 - - - Transposase 248217 1.35433844447563 2.90999622627431 1.00161707165021 3432 Predicted transcriptional regulator K conserved protein 248218 1.3451494067912 3.01572596769812 1.03135875968107 470 ATPase involved in DNA replication L replication factor C subunit 248219 1.28760769691775 3.06870118690439 1.05846372592978 4002 Predicted phosphotransacetylase R N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase subunit X 248220 1.21141762218698 2.87675968228021 0.998388701371313 4063 Tetrahydromethanopterin S-methyltransferase, subunit A H N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase subunit A 248221 1.29721488966708 3.00861810209703 1.03761736581655 1962 Tetrahydromethanopterin S-methyltransferase, subunit H H N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase subunit H 248222 1.37176208345046 3.08404302802024 0.952658332065527 - - - hypothetical protein 248223 1.29253201078649 2.97679202187959 0.920887606986432 - - - Transposase 248224 1.27504926778638 2.99318668448074 1.03552629888128 129 Dihydroxyacid dehydratase/phosphogluconate dehydratase EG Dihydroxy-acid dehydratase 248225 1.29147128135413 2.90885767017761 1.03424871890558 2202 FOG: PAS/PAC domain T putative sensory transduction protein kinase 248226 1.36955444420227 3.11081917274024 1.01511150791587 426 Uncharacterized flavoproteins C Uncharacterized flavoprotein 248227 1.31329910165829 2.96348655614599 1.01844119241459 4742 Predicted transcriptional regulator K conserved protein 248228 1.28829252266138 2.93922818471909 1.02535945626392 - - - conserved protein 248229 1.4242041179999 3.16585018570516 1.03987051061835 - - - conserved protein 248230 1.3059257607414 3.25315160547157 1.13838485183742 3291 FOG: PKD repeat R conserved protein 248231 1.262766871478 2.86096260071291 1.00485255455811 4742 Predicted transcriptional regulator K conserved protein 248232 1.29655055661164 2.74043054967249 1.00123966066499 - - - conserved protein 248233 1.43055369705216 3.44914957745448 1.08047202018866 - - - conserved protein 248234 1.27371813532257 2.94855226852759 1.01631964031078 5513 Predicted secreted protein S hypothetical protein 248235 1.30980384948743 3.00525010597109 1.00266233348926 - - - conserved protein 248236 1.33613854831129 2.90966888653212 0.990338558595112 - - - conserved protein 248237 1.37265959668823 3.06787825278832 1.0174029696439 - - - hypothetical protein 248238 1.35331633299491 3.08742917600936 0.946093196741146 - - - hypothetical protein 248239 1.38071339593006 3.19072041477372 0.9698743175944 1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes I putative endonuclease 248240 1.30459888443666 3.10752035302617 0.994524403703748 - - - hypothetical protein 248241 1.34755752040451 3.12587155667513 0.965391901806738 1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster R Superfamily II DNA and RNA helicase 248242 1.27851985374898 2.9281786354421 0.930184021154809 1194 A/G-specific DNA glycosylase L T/G-specific DNA glycosylase 248243 1.29549337948025 2.87891812930368 0.951048321844645 270 Site-specific DNA methylase L DNA-cytosine methyltransferase 248244 1.32699387707517 2.9834384490007 1.00605110978358 308 Aminopeptidase N E Membrane alanine aminopeptidase 248245 1.3144472628742 3.03502634780813 1.04520343137905 4828 Predicted membrane protein S hypothetical protein 248246 1.39181289738798 3.24039563897759 1.11663918684903 4828 Predicted membrane protein S hypothetical protein 248247 1.28141289068813 2.97279368102595 1.04006536126698 498 Threonine synthase E Threonine synthase 248248 1.29808628745698 2.90726460447027 0.993665873211615 495 Leucyl-tRNA synthetase J Leucyl-tRNA synthetase 248249 1.25209184033341 2.76951113419817 0.975005215948099 388 Predicted amidohydrolase R putative amidohydrolase 248250 1.31362508783372 2.9624539771255 0.998304590004216 - - - conserved protein 248251 1.29490387905194 3.11917920491496 1.0340058503143 1945 Uncharacterized conserved protein S hypothetical protein 248252 1.30164509258078 3.05001743210448 1.07375270422564 1899 Deoxyhypusine synthase O deoxyhypusine synthase 248253 1.31546553662749 3.01534691372128 1.06706241504951 4860 Uncharacterized protein conserved in archaea S transcriptional regulator, ArsR family 248254 1.27875429741104 2.99148155743276 1.0313935266684 1497 Predicted transcriptional regulator K transcriptional regulator 248255 1.26991751645039 2.91100668051286 1.02893417196201 622 Predicted phosphoesterase R hypothetical protein 248256 1.3131921925006 3.12068546391203 1.03707026672261 - - - hypothetical protein 248257 1.29984819436315 2.9285330932261 1.03406263513469 3390 Uncharacterized protein conserved in archaea S conserved protein 248258 1.26909381825732 2.89212017780687 0.99526588624071 1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-bin L conserved protein 248259 1.29955597303056 3.16135637081896 1.08166246125878 25 NhaP-type Na+/H+ and K+/H+ antiporters P Na(+)/H(+) antiporter, putative 248260 1.30953721461165 3.2372464250012 1.11151924027118 1174 ABC-type proline/glycine betaine transport systems, permease component E Glycine betaine transport system, permease protein 248261 1.28494505770401 3.20432598070008 1.07835829179032 1174 ABC-type proline/glycine betaine transport systems, permease component E Glycine betaine transport system, permease protein 248262 1.32932323457889 3.11044200846869 1.07457899704291 1125 ABC-type proline/glycine betaine transport systems, ATPase components E Glycine betaine transporter, ATP-binding protein 248263 1.28329601455589 2.89002140293039 0.996180755451985 1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprote M Glycine betaine-binding protein 248264 1.28158162781938 3.00922603464715 1.03785841698235 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ Glucose-1-phosphate thymidylyltransferase 248265 1.30199900818385 2.99230675298516 1.05679267090125 449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains M Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 248266 1.31518641038765 3.02414554707969 1.05757894930812 1109 Phosphomannomutase G phosphoglucomutase 248267 1.29876208427773 3.05269445177537 1.06917199927659 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ Glucose-1-phosphate thymidylyltransferase 248268 1.3887916745906 3.32898809337982 1.0648611432797 - - - hypothetical protein 248269 1.28569871298907 2.89603044459829 0.99667855067316 1223 Predicted ATPase (AAA+ superfamily) R AAA family ATPase 248270 1.24603673955188 2.8800057432664 0.981864019377679 - - - conserved protein 248271 1.30104270097541 3.07178754513241 1.04749457624993 1234 Metal-dependent hydrolases of the beta-lactamase superfamily III R metal dependent hydrolases 248272 1.29634981855104 3.02291865260777 1.04269222068773 7 Uroporphyrinogen-III methylase H Uroporphyrin-III C-methyltransferase 248273 1.29789392248229 2.95774927540954 1.05198140471734 1587 Uroporphyrinogen-III synthase H Uroporphyrinogen-III synthase 248274 1.28828084091611 2.88984321636139 1.00020551319883 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 248275 1.42641243474254 3.1617678315246 0.994361042046054 3173 Predicted aminoglycoside phosphotransferase R hypothetical protein 248276 1.27072680700835 2.84063833591681 0.99461562980424 - - - conserved protein 248277 1.31489949980555 2.91349252088624 1.00209494949335 1011 Predicted hydrolase (HAD superfamily) R hypothetical protein 248278 1.25923043212199 2.80603209496519 0.999391062182889 1011 Predicted hydrolase (HAD superfamily) R hypothetical protein 248279 1.28947149978033 2.91119472534456 1.0262521673309 525 Valyl-tRNA synthetase J Valyl-tRNA synthetase 248280 1.32433457091155 3.03202850383869 0.989058250617666 - - - hypothetical protein 248281 1.32049188707078 3.16547193189958 1.11848010153665 1955 Archaeal flagella assembly protein J NU flagella related protein FlaJ 248282 1.2602034904717 2.88784107248129 1.02280342249193 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU flagella related protein FlaI 248283 1.34554065181779 3.12405843952032 1.03794247483179 2874 Predicted ATPases involved in biogenesis of archaeal flagella NU flagella related protein FlaH 248284 1.33574969391255 3.24251723256345 1.105303181939 - - - conserved protein 248285 1.24115538021387 3.02336397355613 1.04306983866674 - - - hypothetical protein 248286 1.27346231332157 2.78906139635757 0.974707995112203 - - - hypothetical protein 248287 1.32118727398233 3.13803879395789 0.999471081620259 1681 Archaeal flagellins N Flagellin B1 precursor 248288 1.33778140831005 3.20163285414968 1.02649277081451 1681 Archaeal flagellins N Flagellin B1 precursor 248289 1.30951954107143 3.0912930683302 0.955082642931297 - - - hypothetical protein 248290 1.29132457509666 2.94019999289463 1.02535822689269 1352 Methylase of chemotaxis methyl-accepting proteins NT chemotaxis protein methyltransferase 248291 1.28593594554888 3.11041818208786 1.02033511292212 1871 Chemotaxis protein; stimulates methylation of MCP proteins NT Chemotaxis protein 248292 1.34870754448652 3.20833823960282 1.06018296134793 1776 Chemotaxis protein CheC, inhibitor of MCP methylation NT Chemotaxis protein 248293 1.3056897872107 2.9980371001001 1.0658957964697 643 Chemotaxis protein histidine kinase and related kinases NT Chemotaxis protein 248294 1.32796307124868 3.14578873389631 1.08341324751352 2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain NT protein-glutamate methylesterase 248295 1.26371469583266 2.77435057902239 1.02371460821796 4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain T Chemotaxis protein 248296 1.25603434300985 2.91266014178323 0.992099972303334 2469 Uncharacterized conserved protein S hypothetical Exported protein 248297 1.35827435697526 3.12043619086602 1.05337008273905 835 Chemotaxis signal transduction protein NT Chemotaxis protein 248298 1.29330882778544 2.94996161501067 1.0421336567008 840 Methyl-accepting chemotaxis protein NT Methyl-accepting chemotaxis protein 248299 1.36150215089456 3.04332548076712 1.04655216451694 - - - hypothetical protein 248300 1.28076536796686 2.96189438167564 1.04578211611966 1257 Hydroxymethylglutaryl-CoA reductase I 3-hydroxy-3-methylglutaryl-coenzyme A reductase 248301 1.29244604030715 2.91565934320377 1.01369564177658 - - - conserved protein 248302 1.27353355381401 2.88449880426338 0.984946729980807 1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) R Tryptophan synthase, beta chain 248303 1.27872580546846 3.01119776601444 1.05203721899296 351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase H putative phosphomethylpyrimidine kinase 248304 1.38368400787166 3.30122385651814 1.09887486298703 1958 Small nuclear ribonucleoprotein (snRNP) homolog K putative snRNP Sm-like protein 248305 1.36736368552839 3.09583939416618 1.1131064821253 2126 Ribosomal protein L37E J LSU ribosomal protein L37E 248306 1.28481957370634 3.03023081723343 1.06399033406948 34 Glutamine phosphoribosylpyrophosphate amidotransferase F Amidophosphoribosyltransferase 248307 1.41194169013008 3.32545419455357 1.06808431914168 432 Uncharacterized conserved protein S hypothetical protein 248308 1.17980031510961 2.58330537519993 0.924766318912181 - - - hypothetical protein 248309 1.30528901431366 3.18235841954715 1.10456903460468 534 Na+-driven multidrug efflux pump V putative cation efflux pump 248310 1.36257037149256 2.97323876616925 1.02413865051109 1378 Predicted transcriptional regulators K transcriptional regulator 248311 1.32019997209136 2.93645349970485 0.985861464371953 1846 Transcriptional regulators K transcriptional regulator, MarR family 248312 1.33498092799599 3.06815554327741 0.999197671822702 - - - hypothetical protein 248313 1.30328823664887 3.20544658124426 1.12701415331331 534 Na+-driven multidrug efflux pump V putative cation efflux pump 248314 1.42889091234337 3.13877236578157 1.00299868467293 - - - hypothetical protein 248315 1.35314352257648 3.09622555940932 1.04394278726301 607 Rhodanese-related sulfurtransferase P putative molybdopterin biosynthesis protein 248316 1.29999883609896 2.96381626344148 1.03880594681586 - - - conserved protein 248317 1.28673186499991 3.0161849077186 1.04048619460201 - - - hypothetical protein 248318 1.18095282735863 2.833839152861 0.939595040316995 - - - conserved protein 248319 1.39954019379913 3.35042191294303 1.07386677562787 - - - hypothetical protein 248320 1.46862080292894 3.30169712053291 0.97954379858167 1943 Transposase and inactivated derivatives L Transposase 248321 1.29593373950386 3.07755305563495 1.07356461463867 - - - conserved protein 248322 1.28076429046853 2.95764776282739 1.05088475214719 334 Glutamate dehydrogenase/leucine dehydrogenase E glutamate dehydrogenase 248323 1.2792253819015 2.96777343101801 1.03774727492188 1042 Acyl-CoA synthetase (NDP forming) C Acetyl-CoA synthetase, alpha subunit 248324 1.28228779851052 2.87111955667571 1.04324868931012 1733 Predicted transcriptional regulators K hypothetical protein 248325 1.33051832338122 3.06059994824871 1.04806268915398 1251 NAD(P)H-nitrite reductase C Sulfite reductase, assimilatory-type 248326 1.28362142184831 2.70525691005746 0.963932851059731 1733 Predicted transcriptional regulators K transcriptional regulator, MarR family 248327 1.30555705242728 2.9664009804286 1.05098967746108 1251 NAD(P)H-nitrite reductase C Sulfite reductase, assimilatory-type 248328 1.2817850029839 2.92414151154995 1.02769132111699 662 Mannose-6-phosphate isomerase G hypothetical protein 248329 1.35412594355281 3.01602347470381 0.997341472603331 5561 Predicted metal-binding protein S hypothetical protein 248330 1.35368675547032 2.97334031773892 0.982369306326272 - - - conserved protein 248331 1.26653017235376 2.73850021470239 0.922880875540795 1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain C Ferredoxin 248332 1.33416815424084 2.86516509759822 0.980928176224028 3945 Uncharacterized conserved protein S hypothetical protein 248333 1.31521153705329 3.0093908753471 1.03359028359087 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S hypothetical protein 248334 1.30777814334919 2.97489165476428 1.00556638520778 1378 Predicted transcriptional regulators K hypothetical protein 248335 1.33336207151704 3.1146675098207 1.08342435447119 77 Prephenate dehydratase E chorismate mutase 248336 1.38472950852353 3.22002458763298 1.05711709178716 - - - conserved protein 248337 1.2977651275744 2.93705393499855 1.02265162039185 714 MoxR-like ATPases R MoxR-like ATPase 248338 1.32300128496263 3.04047850386834 1.03228599164979 1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) R hypothetical cytosolic protein 248339 1.30485084058188 3.17020112297891 1.11846452741575 - - - conserved protein 248340 1.27081374130488 2.98917578411468 1.0471747011659 - - - conserved protein 248341 1.22581655784587 2.9588523342614 1.0245547765282 170 Dolichol kinase I conserved protein 248342 1.31110198713372 3.22172441311595 1.10578249567398 392 Predicted integral membrane protein S integral membrane protein 248343 1.26469176450584 2.98590045238918 1.01596860188058 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar-phosphate nucleotydyl transferase 248344 1.38271376288999 3.24842455347494 1.08075236852287 - - - conserved protein 248345 1.27680180233071 2.82478651799963 0.966250577042118 1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 O Peptidyl-prolyl cis-trans isomerase 248346 1.25602388013181 2.82977704243213 0.970821268725489 1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 O Peptidyl-prolyl cis-trans isomerase 248347 1.26987158501389 2.80694276039953 1.00063762813196 1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 O Peptidyl-prolyl cis-trans isomerase 248348 1.28288409562208 3.02970583293586 1.03822861694467 5658 Predicted integral membrane protein S hypothetical protein 248349 1.3013259370565 3.12040718948861 1.08597351352325 3291 FOG: PKD repeat R conserved protein 248350 1.32446030248875 3.10496892523445 1.03199522667615 4738 Predicted transcriptional regulator K hypothetical protein 248351 1.37997107368933 3.1458266610002 1.03186326969782 4738 Predicted transcriptional regulator K hypothetical protein 248352 1.27225087785574 2.93061664438684 1.03515498293051 1148 Heterodisulfide reductase, subunit A and related polyferredoxins C heterodisulfide reductase subunit HdrA 248353 1.27368172029634 2.85088387241586 0.997090519498706 1150 Heterodisulfide reductase, subunit C C heterodisulfide reductase subunit HdrC 248354 1.28222249949214 2.84619981713081 0.983820441753472 2048 Heterodisulfide reductase, subunit B C heterodisulfide reductase subunit HdrB 248355 1.26847472049228 3.23517353829291 1.05851929434242 3391 Uncharacterized conserved protein S putative surface layer protein 248356 1.25946821348941 3.17404526314121 1.01199085218288 5276 Uncharacterized conserved protein S hypothetical protein 248357 1.2290244659732 2.71955925213722 0.92000864327654 2048 Heterodisulfide reductase, subunit B C hypothetical protein 248358 1.29810608736784 2.89449143744077 0.920570046670704 - - - conserved protein 248359 1.3853314655936 3.20879624577585 0.912429230130461 - - - conserved protein 248360 1.32944452606419 3.38675533846915 1.06526693332934 3391 Uncharacterized conserved protein S putative surface layer protein 248361 1.35027523300376 2.85527078332441 0.904425034198443 3436 Transposase and inactivated derivatives L Transposase 248362 1.4870876986477 3.43697792061466 0.964986698842284 - - - Transposase 248363 1.38086542818859 3.12768657106189 0.97288601137223 - - - conserved protein 248364 1.28845252122013 2.83413833391443 0.977245418352723 2048 Heterodisulfide reductase, subunit B C hypothetical protein 248365 1.30293589442197 2.88346527684779 0.917676060026107 - - - conserved protein 248366 1.28591004998511 2.843862901038 0.914328546163668 - - - conserved protein 248367 1.35784395744176 3.09626287991931 0.960516812437464 - - - conserved protein 248368 1.29598466933729 2.86532595831524 0.977470451194399 2048 Heterodisulfide reductase, subunit B C hypothetical protein 248369 1.30686928225208 3.10006274960606 1.01248488924237 - - - hypothetical protein 248370 1.32026099772403 3.34261908687496 1.08499685170819 3391 Uncharacterized conserved protein S putative surface layer protein 248371 1.36217957795606 3.16347586885428 0.978433785803137 - - - conserved protein 248372 1.25789485895031 2.77261902760321 0.941368295731851 2048 Heterodisulfide reductase, subunit B C hypothetical protein 248373 1.33397510023209 3.04593696960207 1.02742469220581 - - - hypothetical protein 248374 1.237471820521 2.87322948443121 0.998469198361908 65 3-isopropylmalate dehydratase large subunit E 3-isopropylmalate dehydratase 248375 1.23751258500154 2.49014942096642 0.946097437160365 - - - hypothetical protein 248376 1.27578113258309 2.77863008633067 0.944754603253174 - - - conserved protein 248377 1.29390054203108 3.11319255845197 1.07173987764858 1955 Archaeal flagella assembly protein J NU flagella related protein FlaJ 248378 1.29357173335603 2.93489964018682 1.03225511501537 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU flagella related protein FlaI 248379 1.30794832876618 2.95656805602403 1.00498166325892 2874 Predicted ATPases involved in biogenesis of archaeal flagella NU flagella related protein FlaH 248380 1.24301848738707 2.98897787177319 1.02607138942446 - - - conserved protein 248381 1.31006624358012 3.12563637213829 1.03631536783154 - - - conserved protein 248382 1.31509585917062 2.91028627135852 1.01218434487722 - - - conserved protein 248383 1.35417330263063 3.24048891467576 1.08798506186582 1681 Archaeal flagellins N Flagillin B1 248384 1.24589054764981 2.76752061540773 0.976086210944814 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C pyruvate synthase subunit beta 248385 1.31463776646849 2.96967134888143 1.04429146038367 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C pyruvate synthase subunit alpha 248386 1.35169088301102 2.98291972402736 0.93279482610507 675 Transposase and inactivated derivatives L Transposase 248387 1.43691869344621 3.14314161598678 0.933751224962249 1943 Transposase and inactivated derivatives L Transposase 248388 1.34766897741229 3.04058751917918 0.996686392969389 - - - conserved protein 248389 1.32354434186629 3.11653163566494 1.04068268195918 141 Histidinol dehydrogenase E Histidinol dehydrogenase 248390 1.31862028840084 3.06312059703111 1.06796933327807 1204 Superfamily II helicase R helicase 248391 1.29166502650498 2.95315366726393 1.02708242421399 1245 Predicted ATPase, RNase L inhibitor (RLI) homolog R RNase L inhibitor 248392 1.31286319045099 2.98774535246201 1.03128312960939 - - - hypothetical protein 248393 1.3441823330265 3.1362781985881 1.07294829599296 1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing J conserved protein 248394 1.38750979067287 3.01251786345821 0.962006507707679 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system methylation subunit 248395 1.43236021658784 3.22446823842727 1.02939595062594 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 248396 1.45447482264335 3.22329092908643 1.02467758082583 610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V type I restriction-modification system restriction subnit 248397 1.36747355224877 3.0462565286353 0.99720476529014 1309 Transcriptional regulator K transcriptional regulator 248398 1.28429254580754 2.89690908680086 0.997344025992296 - - - conserved protein 248399 1.27219995576536 2.86281388766306 0.998131413334427 - - - conserved protein 248400 1.24712737706261 2.82068748206592 1.0093681814433 - - - conserved protein 248401 1.39382671571436 3.04244369945118 1.05534481723435 3118 Thioredoxin domain-containing protein O Thioredoxin 248402 1.31119806178617 3.09290659909047 1.08037788013176 1478 Uncharacterized conserved protein S hypothetical protein 248403 1.32418858587237 3.09289193285691 1.03286845528324 685 5,10-methylenetetrahydrofolate reductase E Methylenetetrahydrofolate reductase 248404 1.28882339307462 3.03287899597791 1.01406072032895 - - - zinc-finger protein 248405 1.33575451272242 3.16814246406852 1.10897805958253 294 Dihydropteroate synthase and related enzymes H Dihydropteroate synthase 248406 1.26100763558899 2.92854385997207 1.01135915828891 190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase H Methylenetetrahydrofolate dehydrogenase (NADP+) 248407 1.27490288129444 2.93522898491165 1.00845260845273 112 Glycine/serine hydroxymethyltransferase E Serine hydroxymethyltransferase 248408 1.33141912683479 3.07173648759692 1.07117377656532 299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN F Phosphoribosylglycinamide formyltransferase 248409 1.35460190420883 3.1926276168134 1.10739025920301 1395 Predicted transcriptional regulator K HTH DNA-binding protein 248410 1.27850741982043 2.91046137818018 1.02706908605569 1571 Predicted DNA-binding protein containing a Zn-ribbon domain R hypothetical protein 248411 1.29175260527335 3.08618198858531 1.04940795679588 171 NAD synthase H NAD(+) synthetase 248412 1.33525696157165 2.99672114164524 1.0452214518561 464 ATPases of the AAA+ class O Cell division control protein 248413 1.21189668273698 2.83628721880946 1.04698693397908 1873 Uncharacterized conserved protein S hypothetical protein 248414 1.31821603390749 2.91499701234715 0.916659654340079 2230 Cyclopropane fatty acid synthase and related methyltransferases M SAM-dependent methyltransferases 248415 1.25445611218229 2.79814757073102 0.863173335414113 2320 Uncharacterized conserved protein S conserved protein 248416 1.32703925923506 2.83473531376277 0.945530931884809 - - - hypothetical protein 248417 1.33646091217518 2.89477610231207 0.829459489443858 - - - hypothetical protein 248418 1.3873258409174 3.10368577374742 0.988787373934677 - - - conserved protein 248419 1.35399733408515 3.15713905442027 1.01447620393684 - - - hypothetical protein 248420 1.28563613813533 2.76479972002044 0.950493155164331 1305 Transglutaminase-like enzymes, putative cysteine proteases E hypothetical protein 248421 1.28706203717908 2.92004707588756 1.02930238635299 561 Predicted hydrolases of the HAD superfamily R hydrolase 248422 1.29014436188469 2.96846881429491 1.03901982891826 468 RecA/RadA recombinase L recombination/repair protein RadA 248423 1.32241892020884 2.98008381307892 0.978971972506762 1019 Predicted nucleotidyltransferase R cytidylytransferase 248424 1.24190092227694 2.69675983362247 0.977822659747891 - - - conserved protein 248425 1.27203206599544 2.9108405811382 0.979975412225049 648 Endonuclease IV L putative endonuclease IV 248426 1.30039678925651 2.82798750597855 0.99434187640122 620 Methionine synthase II (cobalamin-independent) E 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 248427 1.27303931899759 2.92316536196944 1.0224099516696 1122 ABC-type cobalt transport system, ATPase component P Cobalt transport ATP-binding protein 248428 1.36331388433616 3.37367472346032 1.11406641472349 619 ABC-type cobalt transport system, permease component CbiQ and related transporters P Cobalt transport protein 248429 1.2625299037189 2.86967100639662 1.02570744396808 1930 ABC-type cobalt transport system, periplasmic component P Cobalt transport protein 248430 1.3468002131695 3.34396553306553 1.14274538204547 310 ABC-type Co2+ transport system, permease component P CbiM protein 248431 1.28028758027844 3.17424313411558 1.07464731697524 1238 Predicted membrane protein S conserved protein 248432 1.29574926312542 3.10704994583366 1.10439072905271 - - - conserved protein 248433 1.28149122842708 3.05709943401674 1.07499684978034 1738 Uncharacterized conserved protein S hypothetical protein 248434 1.27676133114706 2.84985071570602 1.00087927757143 1746 tRNA nucleotidyltransferase (CCA-adding enzyme) J tRNA nucleotidyltransferase 248435 1.48590878316194 3.53984951255757 0.850671471364407 - - - hypothetical protein 248436 1.29627700461815 2.89634812218434 1.00371573362528 122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase L 8-oxoguanine DNA glycosylase 248437 1.29731657105592 2.96604279579263 1.03771514634752 4809 Archaeal ADP-dependent phosphofructokinase/glucokinase G Glucokinase 248438 1.27957016480306 2.90614684333639 1.03215553351785 4809 Archaeal ADP-dependent phosphofructokinase/glucokinase G ADP-dependent phosphofructokinase 248439 1.31806188459467 3.12387409960168 1.09533854098686 1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase) E glutamate N-acetyltransferase 248440 1.27805717678013 3.00799734540055 1.0478338186698 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K putative inosine-5'-monophosphate dehydrogenase 248441 1.32578933479136 3.17613925570404 1.0901943851272 2 Acetylglutamate semialdehyde dehydrogenase E N-acetyl-gamma-glutamyl-phosphate reductase 248442 1.32189888652988 3.14950631555132 1.07944947006204 3430 Uncharacterized protein conserved in archaea S hypothetical protein 248443 1.39588091470056 3.05384476595398 0.980561069016663 3613 Nucleoside 2-deoxyribosyltransferase F hypothetical protein 248444 1.44859280902088 3.57656253224042 1.08349127431888 - - - conserved protein 248445 1.54563714591378 3.42693697450671 0.988457712815877 - - - hypothetical protein 248446 1.24929618956595 2.72988459966685 0.974356942859072 - - - Acetyltransferase 248447 1.26407874034664 2.64138777737253 0.904550336573168 - - - hypothetical protein 248448 1.32152769352751 2.90573954998275 0.999539963958625 71 Molecular chaperone (small heat shock protein) O Small heat shock protein 248449 1.32325647432992 2.98052697641299 1.0055372223547 2078 Uncharacterized conserved protein S hypothetical protein 248450 1.27725543881058 2.99334510690419 1.05142740711438 126 3-phosphoglycerate kinase G Phosphoglycerate kinase 248451 1.29399002515769 2.84501292172465 0.949086313753586 1573 Uracil-DNA glycosylase L DNA polymerase 248452 1.21613409787643 2.70228071344582 0.958557403660539 71 Molecular chaperone (small heat shock protein) O Heat shock protein 248453 1.33046674710023 2.77797820362388 0.986750866587971 1146 Ferredoxin C Ferredoxin 248454 1.23818844218844 2.57791186776669 0.965104352192847 - - - Ferredoxin 248455 1.3930997810575 3.20023325147653 1.06440221348043 1413 FOG: HEAT repeat C Phycocyanin alpha-subunit phycocyanobilin lyase 248456 1.30649424776735 3.13056118009737 1.04030731248448 - - - conserved protein 248457 1.36163108241109 3.20637379690016 1.06490784026292 2512 Uncharacterized membrane-associated protein/domain S conserved protein 248458 1.40982679736121 3.23873249498794 1.04865202824578 1042 Acyl-CoA synthetase (NDP forming) C Acetyl-CoA synthetase, beta subunit 248459 1.65243211262272 4.02482649098473 1.17111809305609 - - - hypothetical protein 248460 1.27352508230467 2.94903462121435 1.01435535039178 282 Acetate kinase C Acetate kinase 248461 1.27661975107466 2.96342944760451 1.00956011247619 280 Phosphotransacetylase C Phosphate acetyltransferase 248462 1.22276319810482 2.75622019901038 0.962064236589996 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 248463 1.32496045497254 3.23289591732601 1.11413016322091 38 Chloride channel protein EriC P putative chloride channel protein 248464 1.41205622209084 3.07017449853863 0.964551932855519 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S conserved protein 248465 1.33260199150545 2.9020980903352 0.93222178384168 3832 Uncharacterized conserved protein S hypothetical protein 248466 1.3865970214931 3.05385441602079 1.01135656319345 3865 Uncharacterized protein conserved in bacteria S 3-demethylubiquinone-9 3-methyltransferase 248467 1.35414466777925 3.05975495270951 1.04478720117165 251 Putative translation initiation inhibitor, yjgF family J Translation initiation inhibitor 248468 1.42851148464086 3.46261328464474 1.1373056543318 - - - hypothetical protein 248469 1.31554944487264 2.9836222299123 1.04550246711506 1413 FOG: HEAT repeat C Phycocyanin alpha-subunit phycocyanobilin lyase 248470 1.26125398972896 2.92485869389297 1.02488994092766 407 Uroporphyrinogen-III decarboxylase H Methylcobalamin:Coenzyme M methyltransferase MtbA 248471 1.39217075590932 3.08379122164269 1.00651981500206 662 Mannose-6-phosphate isomerase G conserved protein 248472 1.30624279839966 2.95186827060129 0.995359087414892 - - - conserved protein 248473 1.31833412601148 3.08647049788802 1.07142565537469 613 Predicted metal-dependent phosphoesterases (PHP family) R Isoleucyl-tRNA synthetase 248474 1.32613642457535 2.96050549023781 0.996519300705183 5421 Transposase L Transposase 248475 1.28022293309905 2.91299284482319 1.01948902753057 2262 GTPases R GTP-binding protein 248476 1.35556425763047 3.06435635957908 1.00374637815845 4921 Uncharacterized protein conserved in archaea S conserved protein 248477 1.28962127229573 2.92835767449277 1.00436500248212 1676 tRNA splicing endonuclease J tRNA-intron endonuclease 248478 1.3035804893348 3.08802401597453 1.07557734189564 1797 Cobyrinic acid a,c-diamide synthase H Cobyrinic acid a,c-diamide synthase 248479 1.28748911123809 2.94392830550263 1.03327601858567 1348 Nitrogenase subunit NifH (ATPase) P nitrogenase iron protein 2 248480 1.29712858645778 2.91355380450724 1.02188728216573 2710 Nitrogenase molybdenum-iron protein, alpha and beta chains C conserved protein 248481 1.27750496076975 3.06075104836561 1.06277441454593 770 UDP-N-acetylmuramyl pentapeptide synthase M hypothetical protein 248482 1.22430937516049 2.82625887789142 0.987692811102571 2138 Uncharacterized conserved protein S conserved protein 248483 1.3234389674925 2.99324043159043 1.04627105924236 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 248484 1.44541609878166 3.38830470206165 1.07600946767744 - - - hypothetical protein 248485 1.29843165537517 2.83435355678227 0.980239903900091 - - - hypothetical protein 248486 1.32345846997902 2.89008721177293 0.967963248900005 - - - conserved protein 248487 1.35538773978052 3.0725204048025 0.92451933888601 3547 Transposase and inactivated derivatives L Transposase 248488 1.39391685072114 3.00858828878972 1.00472976616656 - - - hypothetical protein 248489 1.36157520697591 3.37988034520857 1.14292589177283 1808 Predicted membrane protein S hypothetical protein 248490 1.31541034808045 3.0664964013133 1.01798242514443 - - - hypothetical protein 248491 1.3415388662147 3.07683648529827 1.02432728608558 - - - hypothetical protein 248492 1.24619925079735 2.81542818697376 0.982617773774762 - - - conserved protein 248493 1.29226508307272 3.02461524288886 1.08673682586931 - - - hypothetical protein 248494 1.33731565339283 3.11800660965832 1.04728873561394 596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R hydrolase 248495 1.31073718021298 3.15751912732161 1.10547232893581 531 Amino acid transporters E Amino acid permease 248496 1.31148852603218 2.79895223929523 0.885503915352757 - - - conserved protein 248497 1.29839074513514 2.86675149545259 1.00314361482417 - - - hypothetical protein 248498 1.3117411106339 2.80502371206039 0.949948963623448 - - - conserved protein 248499 1.40423952667327 3.47548502453009 1.14350443267109 1835 Predicted acyltransferases I conserved protein 248500 1.19903340604223 2.65288544413644 0.945050731707499 - - - hypothetical protein 248501 1.32854188298249 3.17598686962216 1.06433813344221 - - - hypothetical protein 248502 1.24533823816192 2.7198779468346 0.906929434806145 662 Mannose-6-phosphate isomerase G hypothetical protein 248503 1.30679470712285 2.90257300268317 0.939718591210017 - - - hypothetical protein 248504 1.17861072351768 2.12505988458881 0.748057675482936 - - - hypothetical protein 248505 1.27824084077425 2.92967895105372 1.02583498410987 1408 Predicted phosphohydrolases R conserved protein 248506 1.38081991416944 3.34633023272945 1.09991997951953 - - - conserved protein 248507 1.42051716863794 4.33905013481688 1.30850943656286 - - - hypothetical protein 248508 1.30677993470137 2.97183068211411 1.00838066112938 - - - hypothetical protein 248509 1.50548074901808 3.48688602321153 1.16115144218864 557 Exoribonuclease R K Exoribonuclease II 248510 1.51476415785205 3.54683013508299 1.0224029487016 - - - hypothetical protein 248511 1.32760457731229 2.96903289169849 0.987718571285683 - - - conserved protein 248512 1.56721596572312 3.81475414810791 1.10178019261127 - - - conserved protein 248513 1.45715070510352 3.1317249003322 0.987413240658752 - - - hypothetical protein 248514 1.38744854854756 3.06356131664557 0.881969906971896 3654 Prophage maintenance system killer protein R conserved protein 248515 1.34048295446949 2.86089112770253 0.940727565705619 - - - hypothetical protein 248516 1.30382837126759 2.87909549727223 1.00965357633914 - - - hypothetical protein 248517 1.2692628868969 2.86314802897484 0.95923304680404 - - - hypothetical protein 248518 1.53695733392836 3.64431301207214 1.02038854154496 - - - hypothetical protein 248519 1.52081247279142 3.4740472600312 1.04803940571815 - - - conserved protein 248520 1.48216397349004 3.48249359224762 1.07043283870668 - - - hypothetical protein 248521 1.49051643224774 3.33981085045478 1.17582401283446 - - - hypothetical protein 248522 1.27138134746228 2.77646684561502 0.942397344626227 1468 RecB family exonuclease L hypothetical protein 248523 1.22636171871411 2.7138749048032 0.945925879435715 1343 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 248524 1.26662502489198 2.80385991997786 0.983814654469132 1518 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 248525 1.35091127236284 3.05434349951856 0.980482640432005 - - - hypothetical protein 248526 1.40945780684246 3.10934571371049 0.947492580463156 1203 Predicted helicases R conserved protein 248527 1.40653957953146 3.17071207572896 0.986830691688197 - - - hypothetical protein 248528 1.34768279171378 3.02607337149946 0.972174530026528 3649 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 248529 1.3528063198889 2.94999137721132 0.925594472054964 - - - hypothetical protein 248530 1.26280816906049 2.95570611393236 1.01634172048913 - - - transcriptional regulator 248531 1.29252862854705 2.79421840212818 0.966618938323201 4912 Predicted DNA alkylation repair enzyme L hypothetical protein 248532 1.26122024483957 2.63751552523805 0.928197136366374 1670 Acetyltransferases, including N-acetylases of ribosomal proteins J Acetyltransferase 248533 1.37302950870529 3.35351407062422 1.12105058289847 - - - conserved protein 248534 1.42857001767587 3.17319791524154 1.06783914073107 - - - ABC transporter, ATP-binding protein 248535 1.27067310421555 3.05367577730235 1.07099031757092 1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA P ABC transporter, ATP-binding protein 248536 1.29295785067313 3.04585942304713 1.03871629843267 1409 Predicted phosphohydrolases R transcriptional regulator, Icc related protein 248537 1.29209342549568 3.07867691407424 1.05192203462845 1785 Alkaline phosphatase P Alkaline phosphatase 248538 1.39407018141404 3.35067829744071 1.05236914455249 3431 Predicted membrane protein S conserved protein 248539 1.31556589962454 3.00273040806736 1.00460959245452 394 Protein-tyrosine-phosphatase T arsenate reductase 248540 1.30383717074102 3.0653797195589 1.0361881600474 704 Phosphate uptake regulator P putative phosphate regulatory protein 248541 1.28631580268843 2.93917014599883 0.987880574107563 704 Phosphate uptake regulator P Phosphate transport system protein 248542 1.3783152101368 3.27469190935397 1.04092384912549 1117 ABC-type phosphate transport system, ATPase component P Phosphate transport ATP-binding protein 248543 1.27430712401919 3.07696533058474 1.04948329375877 226 ABC-type phosphate transport system, periplasmic component P Phosphate-binding protein 248544 1.40111140608453 3.14448813889837 1.0372486861328 675 Transposase and inactivated derivatives L Transposase 248545 1.28592259824823 2.85372212763624 0.95532433567505 1011 Predicted hydrolase (HAD superfamily) R hypothetical protein 248546 1.29915415799587 2.9731677617944 1.03653611673265 613 Predicted metal-dependent phosphoesterases (PHP family) R conserved protein 248547 1.29538871410207 2.94510045178961 1.01206529564059 1819 Glycosyl transferases, related to UDP-glucuronosyltransferase GC glycosyltransferase 248548 1.27607321798964 2.89860826304666 0.993066037573366 - - - conserved protein 248549 1.26441541210899 2.84728294445967 0.982022069145227 - - - conserved protein 248550 1.29112774361804 2.98782228537402 1.0444332985847 297 Glycogen synthase G conserved protein 248551 1.25095760209776 2.86318037416713 1.01918760685255 1085 Galactose-1-phosphate uridylyltransferase C Sulfate adenylyltransferase 248552 1.30855894320184 2.96175841485724 1.0422137363856 438 Glycosyltransferase M conserved protein 248553 1.29273836999818 2.84870932854923 0.989659665198882 4749 Uncharacterized protein conserved in archaea S conserved protein 248554 1.32323110079433 2.9626345650658 1.0119825038667 1860 Uncharacterized protein conserved in archaea S conserved protein 248555 1.37037194402391 3.28183481653425 1.11867381198775 371 Glycerol dehydrogenase and related enzymes C putative glycerol 1-phosphate dehydrogenase 248556 1.36538334729094 3.28526292899748 1.10108717300779 1967 Predicted membrane protein S Conserved membrane protein 248557 1.36073150225297 3.16104130892988 1.06943669639958 1300 Uncharacterized membrane protein S integral membrane protein 248558 1.2949286649139 2.89707921704076 1.01401098135768 1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) R conserved protein 248559 1.27097729531498 3.01756206670345 1.07265125902699 5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) J protein translation initiation factor 2 subunit gamma 248560 1.32985262192643 2.99324510763467 1.02710442422387 1412 Uncharacterized proteins of PilT N-term./Vapc superfamily R conserved protein 248561 1.32649421874998 2.99980126306258 1.03852797897654 1095 DNA-directed RNA polymerase, subunit E' K DNA-directed RNA polymerase subunit E' 248562 1.34946554073573 3.09875875898634 1.08428854400394 2093 DNA-directed RNA polymerase, subunit E'' K DNA-directed RNA polymerase subunit E' 248563 1.35196489289317 3.14098822550184 1.05848380943726 1909 Uncharacterized protein conserved in archaea S hypothetical protein 248564 1.28781505726085 2.76870105167596 0.995098387132801 2004 Ribosomal protein S24E J SSU ribosomal protein S24E 248565 1.25560739989212 2.66365832431829 1.01890542484415 1998 Ribosomal protein S27AE J SSU ribosomal protein S27AE 248566 1.31218246857551 2.93773903973876 1.03663702851135 4783 Putative Zn-dependent protease, contains TPR repeats R conserved protein 248567 1.30592707646982 3.00207832908154 1.04937065903676 533 Metal-dependent proteases with possible chaperone activity O O-sialoglycoprotein endopeptidase 248568 1.29608418509473 2.82604170604174 0.98967143393286 127 Xanthosine triphosphate pyrophosphatase F Nucleoside-triphosphatase 248569 1.25110781573635 2.68379135909407 0.95652744352235 - - - conserved protein 248570 1.3202011127389 3.07936029885154 1.02244998630464 - - - conserved protein 248571 1.28833673069244 3.07396658633878 1.04746217573033 1878 Predicted metal-dependent hydrolase R conserved protein 248572 1.18799423989463 2.49770587858328 0.972142069600972 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C Ferredoxin 248573 1.26989266633619 2.78994320206829 0.979096255129471 2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme R putative radical-forming protein 248574 1.33852912129963 3.21984362000949 1.05718395211133 - - - conserved protein 248575 1.32460336084081 3.20275066959455 1.08561632638671 110 Acetyltransferase (isoleucine patch superfamily) R Acetyltransferase 248576 1.35739462183162 3.21903417376421 1.08364516877819 2006 Uncharacterized conserved protein S Iron-sulfur cluster-binding protein 248577 1.32635360676349 2.99498914076879 1.03183301504081 171 NAD synthase H NH(3)-dependent NAD(+) synthetase 248578 1.292488825266 2.83945649310462 0.976350298306273 37 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control D conserved protein 248579 1.31470385588181 3.11813493282591 1.08169541423172 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ Long-chain-fatty-acid--CoA ligase 248580 1.44321576861558 3.33892578036763 1.03245080120272 - - - conserved protein 248581 1.31926807177427 3.01331511938633 0.954832096882388 2091 Phosphopantetheinyl transferase H conserved protein 248582 1.35490133229511 3.23708137812611 1.09147523630344 - - - conserved protein 248583 1.33354707272189 2.97406011142768 1.01487469763527 20 Undecaprenyl pyrophosphate synthase I Undecaprenyl pyrophosphate synthetase 248584 1.28976749041226 2.85479936460054 1.01324737926306 1331 Highly conserved protein containing a thioredoxin domain O conserved protein 248585 1.31712907435153 2.83101695156107 1.00407823655248 4892 Predicted heme/steroid binding protein R conserved protein 248586 1.32419307447065 3.01367106003563 1.0153133724245 - - - hypothetical protein 248587 1.40246562484821 3.037605468982 0.852570194792755 3415 Transposase and inactivated derivatives L Transposase 248588 1.3617752104271 2.99482323334767 0.908648235347848 3335 Transposase and inactivated derivatives L Transposase 248589 1.33324641113245 3.09805919097874 0.979319716048516 - - - hypothetical protein 248590 1.24142142945956 2.74938617044888 0.953019965462999 1936 Predicted nucleotide kinase (related to CMP and AMP kinases) F conserved protein 248591 1.34062181081391 3.17916572968372 1.07477360843548 1056 Nicotinamide mononucleotide adenylyltransferase H Nicotinamide-nucleotide adenylyltransferase 248592 1.33476363889501 2.99635550169524 1.00188838771358 1035 Coenzyme F420-reducing hydrogenase, beta subunit C F420H2 dehydrogenase subunit FpoF 248593 1.25066124716672 2.88709915125408 0.973507663011685 2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-depend C Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase 248594 1.29327103100263 2.69823233820621 0.966796738963509 4855 Uncharacterized protein conserved in archaea S Zinc finger protein 248595 1.29789779560059 2.77725454390581 0.930382951610316 4855 Uncharacterized protein conserved in archaea S Zinc finger protein 248596 1.33799273976374 3.00656143117161 1.00923822981895 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S hypothetical protein 248597 1.20248573300142 2.62348756346519 0.907694414253289 2033 Desulfoferrodoxin C Desulfoferrodoxin 248598 1.24422924461275 2.87921052227342 1.02957702696725 - - - hypothetical protein 248599 1.28680642552281 2.86314229508913 0.9905599648407 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 248600 1.32231456797822 3.02155588567343 1.00237861467628 1036 Archaeal flavoproteins C flavoprotein 248601 1.24156129299593 2.62398887982761 0.934859851339873 1633 Uncharacterized conserved protein S conserved protein 248602 1.4783706131694 3.6818846155809 1.16755752666431 - - - putative flavodoxin 248603 1.26027047405753 2.82826144287135 1.01943040856679 426 Uncharacterized flavoproteins C putative flavodoxin 248604 1.27184989992854 2.96749199586011 1.01470323639868 3527 Alpha-acetolactate decarboxylase Q Alpha-acetolactate decarboxylase 248605 1.25939552261285 2.5913093752549 0.948688078592823 - - - hypothetical protein 248606 1.44376637220939 3.401656501597 1.08777590968558 - - - conserved protein 248607 1.28428424647393 3.05664257520578 1.06641396128863 473 Isocitrate/isopropylmalate dehydrogenase CE Isocitrate dehydrogenase [NADP] 248608 1.31449151069353 3.264451326772 1.11817978761795 1971 Predicted membrane protein S conserved protein 248609 1.31015046987251 3.05774597733561 1.03721415064726 - - - conserved protein 248610 1.27188564552802 2.83007349198043 0.991946248886914 66 3-isopropylmalate dehydratase small subunit E 3-isopropylmalate dehydratase 248611 1.31260971122563 3.12596295782009 1.0929544964774 1287 Uncharacterized membrane protein, required for N-linked glycosylation R Oligosaccharyl transferase 248612 1.30707123128105 3.10589892853557 1.0940294845612 1287 Uncharacterized membrane protein, required for N-linked glycosylation R Oligosaccharyl transferase 248613 1.32596679346329 3.07765756569116 1.03157654956153 438 Glycosyltransferase M glycosyltransferase 248614 1.32614516231874 2.95588134586589 0.974757790558781 438 Glycosyltransferase M glucosyltransferase 248615 1.35158230322094 3.02076449827343 0.948174112489568 438 Glycosyltransferase M mannosyltransferase 248616 1.32936340429648 3.00854280678319 0.957342864255185 1216 Predicted glycosyltransferases R glycosyltransferase 248617 1.3515380300823 3.03119863409464 0.890301506897156 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase 248618 1.25051588534922 2.73672725750759 0.868782321697558 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase involved in cell wall biogenesis 248619 1.33873607576289 3.06427011402582 0.922456469270285 438 Glycosyltransferase M mannosyltransferase 248620 1.44398685277874 3.27448417388894 1.00077200745196 - - - hypothetical protein 248621 1.42941812444568 3.29547408124004 1.02825990034769 1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component GM Polysaccharide ABC transporter, ATP-binding protein 248622 1.38482608092014 3.40075019897304 1.11167204456207 1682 ABC-type polysaccharide/polyol phosphate export systems, permease component GM Polysaccharide ABC transporter, permease protein 248623 1.32816960809091 2.94398631473218 0.947107119379857 451 Nucleoside-diphosphate-sugar epimerases MG GDP-fucose synthetase 248624 1.3404388860614 2.99901774373556 1.01705991316997 1089 GDP-D-mannose dehydratase M GDP-mannose 4,6 dehydratase 248625 1.28031284913685 2.92110101521996 1.03098435600357 836 Mannose-1-phosphate guanylyltransferase M mannose-6-phosphate isomerase 248626 1.30933697372463 3.02592124515671 1.02818339526122 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H methyltransferase 248627 1.31941912580142 2.90063308457491 1.02365390702471 640 Predicted transcriptional regulators K transcriptional regulator, ArsR family 248628 1.20173227752344 2.79141254695166 0.969664984174464 543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases HC putative dihydroorotate dehydrogenase electron transfer subunit 248629 1.333718746777 3.01967149676643 1.06188303703253 493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases ER glutamate synthase [NADPH] 248630 1.3475069572824 3.07068371094099 0.971593997572197 - - - hypothetical protein 248631 1.26273129171942 2.98632810769072 1.02962458800698 864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-bin K putative nickel-responsive regulator NikR 248632 1.26881071168666 2.91191881273021 0.984312088925986 778 Nitroreductase C Nitroreductase family protein 248633 1.25573710085769 2.83339772637955 0.959591804990185 59 Ketol-acid reductoisomerase EH Ketol-acid reductoisomerase 248634 1.29748667854268 3.0798630905037 1.03296454681256 440 Acetolactate synthase, small (regulatory) subunit E Acetolactate synthase small subunit 248635 1.26793413880618 2.92811343832922 1.01825027543574 28 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome) EH Acetolactate synthase large subunit 248636 1.32439388448371 3.10188633935556 1.06837537186498 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase 248637 1.32867097055187 2.87695516773994 0.962178846273984 2348 Uncharacterized protein involved in methicillin resistance V hypothetical protein 248638 1.31228495244047 3.03437389317249 1.06445198908378 1363 Cellulase M and related proteins G conserved protein 248639 1.34151510797044 2.81652102488732 0.986904279562251 1382 Prefoldin, chaperonin cofactor O Prefoldin beta subunit 248640 1.33322428000063 3.17503523386501 1.07171192749205 618 Exopolyphosphatase-related proteins R conserved protein 248641 1.29853119155892 2.99230616273404 1.04230560598222 1541 Coenzyme F390 synthetase H Coenzyme F390 synthetase 248642 1.34750180764205 3.09743994547959 0.984049831999925 4747 ACT domain-containing protein R Acetolactate synthase small subunit 248643 1.3539157866306 3.15643608368084 1.05178842738325 4031 Predicted metal-binding protein R conserved protein 248644 1.27957750486655 2.97354489851485 1.03578919213647 4020 Uncharacterized protein conserved in archaea S conserved protein 248645 1.30256482773077 2.90983929080168 1.01125298073981 1432 Uncharacterized conserved protein S conserved protein 248646 1.32240593395345 2.88218330187556 0.96228698937104 - - - conserved protein 248647 1.39499310285072 3.42377450162607 1.10480091278102 705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) R integral membrane protein 248648 1.42799502490157 3.64686033345277 1.10412009044094 - - - hypothetical protein 248649 1.30304660152195 2.93218085882438 0.953006081900727 1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit C CO dehydrogenase/acetyl-COA synthase alpha subunit 248650 1.26198717253223 2.96921712503196 0.997427536889715 1880 CO dehydrogenase/acetyl-CoA synthase epsilon subunit C CO dehydrogenase/acetyl-COA synthase epsiolon subunit 248651 1.25292004968921 2.76001375326652 0.866820106925549 1614 CO dehydrogenase/acetyl-CoA synthase beta subunit C CO dehydrogenase/acetyl-COA synthase beta subunit 248652 1.33374739722829 3.04378300739176 1.02706139621371 3640 CO dehydrogenase maturation factor D Nitrogenase iron protein 248653 1.30481228571 3.00472769603147 0.992411921497445 2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) C CO dehydrogenase/acetyl-COA synthase delta subunit 248654 1.33130082134838 3.07194182891837 1.00952492144688 1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) C CO dehydrogenase/acetyl-COA synthase gamma subunit 248655 1.27727207032031 2.89264850775886 1.02012895934956 1499 NMD protein affecting ribosome stability and mRNA decay J conserved protein 248656 1.28569067571541 2.96067182057971 1.03792746190001 2232 Predicted ATP-dependent carboligase related to biotin carboxylase R conserved protein 248657 1.31791043165131 2.98176531804009 0.983253174412218 1675 Transcription initiation factor IIE, alpha subunit K Transcription initiation factor IIE, alpha subunit 248658 1.35219201965555 2.99197304292156 1.01954295640565 1418 Predicted HD superfamily hydrolase R conserved protein 248659 1.36551662810832 3.23323664093458 1.08426025057372 638 20S proteasome, alpha and beta subunits O Proteasome, beta subunit 248660 1.27633795247192 2.89862447721533 1.02890875901937 1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH d R cleavage and polyadenylation specificity factor 100 kD subunit 248661 1.33792465856439 3.03296907135008 1.04669608252765 637 Predicted phosphatase/phosphohexomutase R Beta-phosphoglucomutase 248662 1.24658705841202 2.89750275731802 1.00411195975212 206 Cell division GTPase D Cell division protein 248663 1.30591215943377 3.04596804275167 1.05917638850689 294 Dihydropteroate synthase and related enzymes H Dihydropteroate synthase 248664 1.2529900576788 2.74909659809374 0.959969229262282 - - - conserved protein 248665 1.28136611238346 3.18744421730635 1.10358957636057 3808 Inorganic pyrophosphatase C vacuolar-type H+-pyrophosphatase 248666 1.31036806249879 3.2624107778796 1.15887792773564 3808 Inorganic pyrophosphatase C vacuolar-type H+-pyrophosphatase 248667 1.33174373454881 3.28708011279027 1.14672766177893 2814 Arabinose efflux permease G hypothetical permease 248668 1.29763521413018 3.22636761702315 1.11382042293743 2814 Arabinose efflux permease G hypothetical permease 248669 1.29300085610866 2.90129063401674 0.979289009526984 2016 Predicted RNA-binding protein (contains PUA domain) J conserved protein 248670 1.19016518938494 2.77711300760449 0.979663780130513 2450 Uncharacterized conserved protein S conserved protein 248671 1.34500225874313 3.13923955967818 1.07715771236839 1779 C4-type Zn-finger protein R Thioredoxin 2 248672 1.27610567144186 2.83291105564256 0.973504148061902 442 Prolyl-tRNA synthetase J Prolyl-tRNA synthetase 248673 1.30550779037527 3.06719930332804 1.0574312460788 2038 NaMN:DMB phosphoribosyltransferase H conserved protein 248674 1.43304925038593 3.41733407024222 1.09309523765035 - - - conserved protein 248675 1.5024272736095 3.37977694912407 1.03091832792176 - - - hypothetical protein 248676 1.32624683147151 2.97437752157037 0.9939256227465 5421 Transposase L Transposase 248677 1.42152231265155 3.27565684752729 1.00047750254554 - - - hypothetical protein 248678 1.41719123534596 3.1343478577087 0.978049620251557 - - - conserved protein 248679 1.2529119597379 2.78192727627238 0.953050196420377 1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes G Fructose-bisphosphate aldolase 248680 1.28507801080637 3.02186697324538 1.07090643419951 469 Pyruvate kinase G Pyruvate kinase 248681 1.26228135414501 2.94337686447665 1.01495282614515 - - - hypothetical protein 248682 1.34895167417371 2.83284722007845 1.00535386095783 - - - hypothetical protein 248683 1.32277516279392 3.00851137119188 1.05535934561606 644 Dehydrogenases (flavoproteins) C oxidoreductase 248684 1.32699444426749 3.06520549235094 0.982066689634234 1348 Nitrogenase subunit NifH (ATPase) P Nitrogenase iron protein 248685 1.30467463324676 2.89786676161113 1.01677360015291 347 Nitrogen regulatory protein PII E nitrogen fixation NifHD region GlnB-like protein 248686 1.28113554490903 2.87423423495336 0.948714463504895 347 Nitrogen regulatory protein PII E NifI(2), GlnB-like protein 248687 1.24891821728722 2.74042118733356 0.949915490861451 2710 Nitrogenase molybdenum-iron protein, alpha and beta chains C Nitrogenase molybdenum-iron protein alpha chain 248688 1.30520844714667 3.09040798926992 1.06049953437255 2710 Nitrogenase molybdenum-iron protein, alpha and beta chains C Nitrogenase molybdenum-iron protein beta chain 248689 1.29537627408924 2.91914311989197 1.03465122641802 2710 Nitrogenase molybdenum-iron protein, alpha and beta chains C Nitrogenase iron-molybdenum cofactor biosynthesis protein 248690 1.27644412038893 2.97292034764887 1.00806701190658 2710 Nitrogenase molybdenum-iron protein, alpha and beta chains C Nitrogenase iron-molybdenum cofactor biosynthesis protein NifN 248691 1.30084383423552 2.99202163975184 1.0309737042316 725 ABC-type molybdate transport system, periplasmic component P Molybdate-binding protein 248692 1.28252296363344 3.167666248038 1.09447259714254 4149 ABC-type molybdate transport system, permease component P Molybdenum transporter, permease protein 248693 1.3640449297594 3.1435920172208 1.07726145818195 3842 ABC-type spermidine/putrescine transport systems, ATPase components E Molybdenum transporter, ATP-binding protein 248694 1.33841448738031 3.04108554570185 1.04349404749769 4564 Signal transduction histidine kinase T conserved protein 248695 1.30942257827972 2.99230341158958 1.05586832496911 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H SAM-dependent methyltransferases 248696 1.35402087252218 3.21595654303002 1.03986596566329 - - - hypothetical protein 248697 1.29137483669351 2.97564113351383 1.03092204376222 347 Nitrogen regulatory protein PII E Nitrogen regulatory protein P-II 248698 1.35156021094668 3.34488066261043 1.14472197792203 4 Ammonia permease P Ammonium transporter 248699 1.34739323914067 2.92827816727017 0.985017555872911 - - - hypothetical protein 248700 1.33389659253494 3.17148280068171 1.07756726389662 1742 Uncharacterized conserved protein S conserved protein 248701 1.32294979553961 3.26262478963988 1.12819440378451 701 Predicted permeases R Transporter 248702 1.19911542172744 2.6509752912196 0.981702776217692 - - - conserved protein 248703 1.28838103545106 2.89570722679315 1.00024551053008 4273 Uncharacterized conserved protein S conserved protein 248704 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 248705 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 248706 1.33534992346573 2.98662182459283 0.990103252435063 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 248707 1.3690317678224 3.28008349615071 1.12208427818233 798 Arsenite efflux pump ACR3 and related permeases P Arsenical-resistance protein 248708 1.28722131352926 2.82812488696838 0.960103995882704 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S conserved protein 248709 1.32725933848185 3.10176450726031 1.07257864346401 - - - conserved protein 248710 1.32383940869575 2.97050436701825 1.0239715693864 2230 Cyclopropane fatty acid synthase and related methyltransferases M conserved protein 248711 1.26694334455969 2.75982211749916 0.958309608442791 - - - conserved protein 248712 1.26091765978874 2.8425571659661 0.989099960933703 513 Superfamily II DNA and RNA helicases LKJ ATP-dependent RNA helicase 248713 1.3557758205872 3.03105048305455 1.03801277765399 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H conserved protein 248714 1.32830645838682 3.10840155870225 1.07671918280139 1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases ER Glutathione-independent formaldehyde dehydrogenase 248715 1.24813122702913 2.9499250448093 1.03755056591894 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ Dihydropyrimidinase 248716 1.32580663239814 2.98135676805562 1.02127559084821 622 Predicted phosphoesterase R putative serine/threonine protein phosphatase 248717 1.32387507838677 3.09272815072182 1.02327614287133 622 Predicted phosphoesterase R conserved protein 248718 1.24905259099748 2.87007623061442 0.979278175981202 603 Predicted PP-loop superfamily ATPase R conserved protein 248719 1.29316939600551 2.99816107423938 1.03144049391538 2029 Uncharacterized conserved protein S conserved protein 248720 1.33948556886194 3.10186195280494 1.03195911808005 602 Organic radical activating enzymes O conserved protein 248721 1.26550042690524 2.81882865695256 1.01105214281169 720 6-pyruvoyl-tetrahydropterin synthase H 6-pyruvoyltetrahydropterin synthase 248722 1.28483473018138 2.8069386087277 0.994034493447466 535 Predicted Fe-S oxidoreductases R NifB protein 248723 1.34197577486864 2.98344767145826 1.0165636022564 - - - conserved protein 248724 1.27119723453972 2.7985258644094 0.979784684498989 535 Predicted Fe-S oxidoreductases R NifB protein 248725 1.21465594341353 2.6997170532867 1.02277148249982 1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain C Ferredoxin 248726 1.29467914132459 3.05360939904368 1.08543095353425 2144 Selenophosphate synthetase-related proteins R thiamin-monophosphate kinase 248727 1.24067226860679 2.73841113251758 0.938145522362994 - - - conserved protein 248728 1.4213458848234 3.05552007394394 1.00063093738366 4004 Uncharacterized protein conserved in archaea S conserved protein 248729 1.38382860125509 3.20817943104905 1.02777069564345 3161 4-hydroxybenzoate synthetase (chorismate lyase) H conserved protein 248730 1.33314410656625 3.07641428712352 1.03365807458902 - - - conserved protein 248731 1.34200036727705 3.07084785766747 0.961477239062256 675 Transposase and inactivated derivatives L Transposase 248732 1.35666118789295 2.85969903585431 0.972183338371192 - - - conserved protein 248733 1.3715265139143 3.03724227617332 0.96792399364922 - - - glycosyltransferase 248734 1.27438911034426 2.87828481568563 0.989538793906671 4186 Predicted phosphoesterase or phosphohydrolase R phosphohydrolase 248735 1.25634875079804 2.81914653759474 0.998502178409333 2404 Predicted phosphohydrolase (DHH superfamily) R conserved protein 248736 1.32821678182662 2.97879553480577 0.995638066614092 5421 Transposase L Transposase 248737 1.2907456959567 2.87618589580159 1.00085560153185 - - - conserved protein 248738 1.32417319143267 2.83118183064292 0.95476831870277 4572 Putative cation transport regulator R putative cation transport regulator 248739 1.3351766590983 3.05918036021999 1.02794380706759 - - - conserved protein 248740 1.24951381036857 2.65497892933099 0.938934605586977 1196 Chromosome segregation ATPases D conserved protein 248741 1.32364844820345 3.18319548153825 1.0878807922889 - - - conserved protein 248742 1.29666591669694 3.04176887759478 1.07628512834045 68 Hydrogenase maturation factor O Hydrogenase maturation protein 248743 1.33391421579628 3.02743580100652 1.01949318546533 1394 Archaeal/vacuolar-type H+-ATPase subunit D C A1AO H+ ATPase subunit D 248744 1.33051856140759 3.07531086296052 0.974142948976005 1156 Archaeal/vacuolar-type H+-ATPase subunit B C A1AO H+ ATPase subunit B 248745 1.31220067496426 3.0264514506417 1.02030636761239 1155 Archaeal/vacuolar-type H+-ATPase subunit A C A1AO H+ ATPase subunit A 248746 1.45441095464385 3.57716616321439 1.16027124345128 1436 Archaeal/vacuolar-type H+-ATPase subunit F C A1AO H+ ATPase subunit F 248747 1.40407485157661 3.19884162110001 1.07934821295179 1527 Archaeal/vacuolar-type H+-ATPase subunit C C A1AO H+ ATPase subunit C 248748 1.42184527305634 3.24130624618565 1.07651447742581 1390 Archaeal/vacuolar-type H+-ATPase subunit E C A1AO H+ ATPase subunit E 248749 1.25615839175779 3.05423403437448 0.920720949230321 - - - A1AO H+ ATPase subunit K 248750 1.33342076519935 3.12200508080206 1.09211413971044 1269 Archaeal/vacuolar-type H+-ATPase subunit I C A1AO H+ ATPase subunit I 248751 1.39804582145706 2.88009374558413 0.994598002070523 - - - A1AO H+ ATPase subunit H 248752 1.43182779916261 3.22458153903584 0.977886777191066 1943 Transposase and inactivated derivatives L Transposase 248753 1.34190006320385 3.09826768340999 1.095919505566 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 248754 1.29799739147432 2.95766480296023 0.990409002163086 142 Geranylgeranyl pyrophosphate synthase H Geranyltranstransferase 248755 1.24933432437746 2.9809673356576 1.0565872967552 2332 Cytochrome c-type biogenesis protein CcmE O hypothetical protein 248756 1.43532108358186 3.32443554457959 1.03234186610887 - - - hypothetical protein 248757 1.25101730818308 2.83609925306521 0.983127641988342 - - - hypothetical protein 248758 1.38160066118329 3.16671446795642 1.01003847358013 1833 Uncharacterized conserved protein S Endonuclease III 248759 1.30482050612064 3.01534128264736 1.05626906726902 1397 ADP-ribosylglycohydrolase O ADP-ribosylglycohydrolase 248760 1.31212590833017 2.95684545947826 0.884490915700488 - - - hypothetical protein 248761 1.43424073234185 3.24222564715374 0.962819530906468 - - - hypothetical protein 248762 1.3571995676715 3.03369896213496 0.999042318868434 - - - hypothetical protein 248763 1.32143159327742 3.05890788341098 1.02267525234585 1222 ATP-dependent 26S proteasome regulatory subunit O 26S proteasome regulatory subunit RPT2/S4 248764 1.48201754482668 3.73225237143205 1.13284919942084 2034 Predicted membrane protein S hypothetical protein 248765 1.27652335168614 2.98623661622854 1.0257244021809 2034 Predicted membrane protein S hypothetical protein 248766 1.29536103263622 2.9640725321207 1.04741281913137 104 Adenylosuccinate synthase F Adenylosuccinate synthetase 248767 1.22519663569286 2.7495895444345 0.915091598304333 2238 Ribosomal protein S19E (S16A) J SSU ribosomal protein S19E 248768 1.41839385524018 3.0039780304888 1.02751643395023 2118 DNA-binding protein R conserved protein 248769 1.30928393102272 3.04261974199809 1.03561430308333 2117 Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-lo J hypothetical ATP-binding protein 248770 1.49800028598104 3.44380717959693 1.14181017207698 - - - LSU ribosomal protein L39E 248771 1.23036130373041 2.64448338591756 0.991369472685939 2097 Ribosomal protein L31E J LSU ribosomal protein L31E 248772 1.28378352686557 3.14029125342689 1.0799291902467 1976 Translation initiation factor 6 (eIF-6) J protein translation initiation factor 6 248773 1.2440419502341 2.72049152686821 1.00073135994073 2157 Ribosomal protein L20A (L18A) J LSU ribosomal protein LX 248774 1.32846824647057 2.89241284978698 1.01186788382419 1730 Predicted prefoldin, molecular chaperone implicated in de novo protein folding O Prefoldin, alpha subunit 248775 1.30341264228964 2.87743221184663 1.0069293396418 552 Signal recognition particle GTPase U signal recognition particle subunit Ffh/SRP54 248776 1.47256836414221 3.57672219592963 1.17549406690357 1983 Putative stress-responsive transcriptional regulator KT Stress-responsive transcriptional regulator 248777 1.25478033166506 2.91185593017942 1.00987898299704 - - - conserved protein 248778 1.31248252047783 3.00792190615087 1.04050124829726 3272 Uncharacterized conserved protein S conserved protein 248779 1.22383144024185 2.70650446771727 0.961947315288774 450 Peroxiredoxin O putative peroxiredoxin 248780 1.46955864706738 3.3582170655687 0.950318718898591 - - - Transposase 248781 1.33028247664921 2.82300415696867 0.901281912656452 3436 Transposase and inactivated derivatives L Transposase 248782 1.3029775882887 3.15184800002877 1.09821556948004 345 Pyrroline-5-carboxylate reductase E Pyrroline-5-carboxylate reductase 248783 1.29732930543298 3.01182415388876 1.05920405096159 263 Glutamate 5-kinase E glutamate 5-kinase 248784 1.27488615701477 2.96185709748826 1.04294863635305 14 Gamma-glutamyl phosphate reductase E Gamma-glutamyl phosphate reductase 248785 1.45371680844346 3.2663113045441 1.03739775874928 1844 Uncharacterized protein conserved in archaea S conserved protein 248786 1.31249258022394 3.03704739550939 1.01584758774755 1658 Small primase-like proteins (Toprim domain) L conserved protein 248787 1.37727701757066 3.35335096834334 1.09907965264087 1872 Uncharacterized conserved protein S hypothetical protein 248788 1.31494242435585 3.07880323996179 1.00886954510702 402 Cytosine deaminase and related metal-dependent hydrolases FR conserved protein 248789 1.23731026043162 3.03344662057614 1.05271700114286 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 248790 1.30696613638897 3.15062213021232 1.10193989600796 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K conserved protein 248791 1.23852970702381 2.89364439758844 1.03562802859936 1985 Pyrimidine reductase, riboflavin biosynthesis H conserved protein 248792 1.29734882293567 2.80533629361989 0.939163796278351 727 Predicted Fe-S-cluster oxidoreductase R conserved protein 248793 1.35496620342728 3.44921166171109 1.165067277259 239 Integral membrane protein possibly involved in chromosome condensation D conserved protein 248794 1.37526507319276 3.37815144590138 1.14017306907265 239 Integral membrane protein possibly involved in chromosome condensation D conserved protein 248795 1.36026520610566 3.26681522066866 1.09546572554817 303 Molybdopterin biosynthesis enzyme H Molybdopterin biosynthesis MoeA protein 248796 1.24456190251287 2.90711920661124 1.00795119624173 1977 Molybdopterin converting factor, small subunit H Molybdopterin converting factor small subunit 248797 1.33010379675305 3.1212827611923 1.10396491577646 4745 Predicted membrane-bound mannosyltransferase O conserved protein 248798 1.25478687645222 2.8379684221228 0.924170448423001 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K conserved protein 248799 1.27687404302982 3.12427191836917 1.08079512429425 475 Kef-type K+ transport systems, membrane components P Na(+)/H(+) antiporter 248800 1.3229344510277 3.14400418737354 1.0950988784014 474 Cation transport ATPase P Cation-transporting ATPase 248801 1.30831019028604 3.00406038780918 1.03631698644863 1232 Protoporphyrinogen oxidase H conserved protein 248802 1.25054518285582 2.81295545553735 0.97204612430311 - - - conserved protein 248803 1.28479711531678 3.00945131233781 1.06729659136064 1012 NAD-dependent aldehyde dehydrogenases C Succinate-semialdehyde dehydrogenase [NADP+] 248804 1.26389287108472 3.01002410021527 1.04751321847435 5427 Uncharacterized membrane protein S conserved protein 248805 1.28631750184916 3.11575453323713 1.10089247501685 392 Predicted integral membrane protein S putative glycosyltransferase 248806 1.3204704859751 2.96259349621631 0.982046871673219 640 Predicted transcriptional regulators K transcriptional regulator, ArsR family 248807 1.29339717212893 3.05534223975742 0.978112423899634 864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-bin K conserved protein 248808 1.27546939147534 2.90891868436102 1.02837407161784 1541 Coenzyme F390 synthetase H Coenzyme F390 synthetase/phenylacetyl-CoA ligase 248809 1.3305170174834 2.89437039567716 0.956869756526237 - - - hypothetical protein 248810 1.29601534035297 3.02635914529545 1.04351947238024 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S conserved protein 248811 1.32128010424715 2.85003292226336 0.963441739796897 - - - conserved protein 248812 1.41416131166407 3.06047534304715 1.05385755494116 - - - conserved protein 248813 1.3173067521671 3.15555655965455 1.08409548682356 - - - conserved protein 248814 1.25048116741485 2.74405176888473 0.91201134402669 1225 Peroxiredoxin O Bacterioferritin comigratory protein 248815 1.36066857115119 3.45109446522215 1.0583680990363 2155 Uncharacterized conserved protein S conserved protein 248816 1.308860454986 3.12640323224428 1.00840510958088 - - - conserved protein 248817 1.30703698071378 2.94937093381267 1.02804090651506 415 Deoxyribodipyrimidine photolyase L Deoxyribodipyrimidine photolyase 248818 1.31955090059128 3.00273494242383 1.02792547742883 1235 Metal-dependent hydrolases of the beta-lactamase superfamily I R conserved protein 248819 1.3249348145114 2.98843063739335 1.04188393329719 464 ATPases of the AAA+ class O Cell division cycle protein 48 homolog 248820 1.2787943785197 2.84231182980692 0.977107155112598 152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase F Phosphoribosylamidoimidazole-succinocarboxamide synthase 248821 1.31853713268955 3.10661587487364 1.07282997284763 1602 Uncharacterized conserved protein S conserved protein 248822 1.42035484542793 3.17537467408386 1.04052090624191 2522 Predicted transcriptional regulator R conserved protein 248823 1.29010182457994 2.85807744335265 0.994128034100797 23 Translation initiation factor 1 (eIF-1/SUI1) and related proteins J protein translation initiation factor 1 248824 1.38326845987921 3.10360891407317 1.05561870102344 4742 Predicted transcriptional regulator K conserved protein 248825 1.25684608123452 2.92027714999637 1.02783382466035 46 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain F Phosphoribosylformylglycinamidine synthase 248826 1.27433749967467 2.93999215879624 1.0191667022587 1449 Alpha-amylase/alpha-mannosidase G Alpha-amylase 248827 1.28230350074328 2.87843898510646 1.00936825578973 1449 Alpha-amylase/alpha-mannosidase G Alpha-amylase 248828 1.30179730870092 3.01519741760527 1.05952454882132 1719 Predicted hydrocarbon binding protein (contains V4R domain) R conserved protein 248829 1.26250748222004 2.84253310330684 0.992620316912211 3387 Glucoamylase and related glycosyl hydrolases G Glucoamylase 248830 1.31681527184629 2.95001655791318 1.03472905686546 172 Seryl-tRNA synthetase J Seryl-tRNA synthetase 248831 1.34978678929898 3.19935408226851 1.07329520747174 616 Periplasmic serine proteases (ClpP class) OU Periplasmic serine protease 248832 1.25565240820979 2.79437975131102 0.98340013915871 143 Methionyl-tRNA synthetase J Methionyl-tRNA synthetase 248833 1.3214209588254 3.02417081799811 1.01587716578446 1437 Adenylate cyclase, class 2 (thermophilic) F Adenylate cyclase 248834 1.30421462652631 3.00788052413335 0.988703521040087 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein 248835 1.27101223456935 2.98627539320591 1.02595576608087 183 Acetyl-CoA acetyltransferase I Beta-ketoacyl synthase/thiolase 248836 1.2994536328113 3.04284412833634 1.07580949935292 3425 3-hydroxy-3-methylglutaryl CoA synthase I Hydroxymethylglutaryl-CoA synthase 248837 1.36633868770024 3.23484091068618 1.08652282691256 1709 Predicted transcriptional regulator K putative transcriptional regulator 248838 1.34727945929354 3.10712145645686 1.08491060154118 - - - conserved protein 248839 1.35826295150223 3.17974760074002 0.936030385591826 - - - conserved protein 248840 1.39722796251527 3.15501158840132 0.970883891615331 - - - hypothetical protein 248841 1.33237737973423 3.22524665407984 0.971964674150237 - - - hypothetical protein 248842 1.45931747843819 3.21006910449217 0.975264299101869 5421 Transposase L Transposase 248843 1.39237968207581 3.00114695102244 1.0154418812293 - - - Transposase 248844 1.30478578561108 3.10035451485963 1.02321938289028 - - - conserved protein 248845 1.27712720757714 2.89177067374221 0.992222460136143 2834 Outer membrane lipoprotein-sorting protein M conserved protein 248846 1.41281432877579 3.03818582669147 0.904468153479259 - - - Transposase 248847 1.44649454840883 3.13315168860915 0.960729524041942 - - - conserved protein 248848 1.34549163079165 3.04474652473382 1.05912620413746 175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related e EH conserved protein 248849 1.32469452834912 2.96358724079874 1.00227342661915 5513 Predicted secreted protein S conserved protein 248850 1.36608573559059 3.24712353217106 1.05172193669695 - - - hypothetical protein 248851 1.29972372238212 3.0806881389318 1.06948758373895 389 Nucleotidyltransferase/DNA polymerase involved in DNA repair L DNA polymerase IV 248852 1.31007645573247 3.02944315333555 1.05482956924545 1122 ABC-type cobalt transport system, ATPase component P Cobalt transporter, ATP-binding protein 248853 1.32967011415114 3.24104382688465 1.06970619381316 619 ABC-type cobalt transport system, permease component CbiQ and related transporters P Cobalt transport protein 248854 1.33326218135919 2.95244046893361 1.00971294708444 3920 Signal transduction histidine kinase T hypothetical protein 248855 1.33184342429954 3.0964848029779 1.04442257527542 - - - putative methyltransferase 248856 1.34803457214906 3.05938888416201 0.978747845420456 - - - putative methyltransferase 248857 1.30533257308241 2.97142476780306 1.03565333284622 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H putative methyltransferase 248858 1.29765389949798 3.23753853364041 1.12050633258387 310 ABC-type Co2+ transport system, permease component P CbiM protein 248859 1.2798535414174 3.12830581156302 1.04992387077002 - - - CbiM protein 248860 1.27903294817771 2.94473256124264 0.991480241728592 177 Predicted EndoIII-related endonuclease L Endonuclease III 248861 1.29662831877391 3.09106851392995 1.06931317730184 1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and re C conserved protein 248862 1.29033755005 2.95009703047335 1.02082846624056 1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and re C Glutathione reductase 248863 1.31179945749103 3.01479235905621 1.07146218243831 138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) F formyltransferase phosphoribosylaminoimidazolecarboxamide 248864 1.32768872880491 3.01453280818814 1.04161155082868 4742 Predicted transcriptional regulator K conserved protein 248865 1.31176785774147 3.16953969495544 1.07216923162257 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H conserved protein 248866 1.31731296344643 3.11910794176126 1.10626669733643 474 Cation transport ATPase P Cation-transporting ATPase 248867 1.31003103079181 2.95132026507664 1.0135204838979 2518 Protein-L-isoaspartate carboxylmethyltransferase O putative methyltransferase 248868 1.35732774733364 3.26484799129512 1.10278942608372 1584 Predicted membrane protein S transcriptional regulator 248869 1.29056231885891 2.95274132683904 1.02261541042172 696 Phosphoglyceromutase G Phosphoglycerate mutase 248870 1.29137583182173 3.00547542372597 1.03196501812253 1907 Predicted archaeal sugar kinases R conserved protein 248871 1.31809298757716 2.94789678518936 1.02083060269399 258 5'-3' exonuclease (including N-terminal domain of PolI) L FLAP endonuclease-1 248872 1.31564998577338 2.96530648345103 1.01961307826637 - - - hypothetical protein 248873 1.23846371075483 2.89941367946269 1.0250078789854 - - - conserved protein 248874 1.36253901003773 3.42886516876057 1.15000430101147 3389 Uncharacterized protein conserved in archaea S conserved protein 248875 1.33069053033303 3.15610210540556 1.05614496550079 4087 Soluble P-type ATPase R potassium/copper-transporting ATPase 248876 1.28003280192057 2.96920400865775 1.04424311388462 1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase R ABC transporter, ATP-binding protein 248877 1.29858266809974 3.00255868849932 1.06352390147108 4070 Predicted peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family O conserved protein 248878 1.37858679927582 3.07930471903332 1.04055953942782 4029 Uncharacterized protein conserved in archaea S conserved protein 248879 1.28334253205252 2.93265071578115 1.00407970847613 4050 Uncharacterized protein conserved in archaea S conserved protein 248880 1.24675354461216 2.96518543449031 1.05455619709112 1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) I conserved protein 248881 1.32126855875075 2.99419578316249 0.999899262466858 4051 Uncharacterized protein conserved in archaea S conserved protein 248882 1.33208263582312 3.10257399663957 1.07967589746803 4052 Uncharacterized protein related to methyl coenzyme M reductase subunit C R conserved protein 248883 1.31129886977174 2.84913602235032 0.963986412090011 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S 4-carboxymuconolactone decarboxylase 248884 1.26960528426066 2.91499763898338 1.01681093511648 5549 Predicted Zn-dependent protease O conserved protein 248885 1.36147594479503 3.07826234536953 0.990626719126489 1051 ADP-ribose pyrophosphatase F MutT related protein 248886 1.31860790114306 3.08646003385024 1.09254899882401 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase 248887 1.2227738634333 2.75523871853313 0.981137047967838 231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) J protein translation initiation factor 5A 248888 1.28613702917435 2.99199831998955 1.04471983113568 10 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family E Agmatinase 248889 1.35834343628249 2.98490800130985 1.02164443571483 - - - conserved protein 248890 1.26611526484418 2.85677832961638 1.04652210692164 - - - conserved protein 248891 1.36539825456358 3.05019792056709 1.01198927807827 5421 Transposase L Transposase 248892 1.24812060434538 2.65230661573745 1.01869553971337 1476 Predicted transcriptional regulators K transcriptional regulator, PBSX family 248893 1.35306109850768 3.28932736544201 1.09278238492809 4854 Predicted membrane protein S conserved protein 248894 1.2809042870124 3.08219715433372 1.09822173998302 475 Kef-type K+ transport systems, membrane components P Glutathione-regulated potassium-efflux system protein 248895 1.34921443571885 3.20070408729015 1.06329898266378 - - - Nitrogen regulatory protein P-II 248896 1.33627775949913 3.3108239014238 1.1112797194514 - - - hypothetical protein 248897 1.37838447326394 3.5600874478958 1.1142511329391 - - - hypothetical protein 248898 1.36174593396054 3.30929537945175 1.15068022099364 4651 Kef-type K+ transport system, predicted NAD-binding component P Glutathione-regulated potassium-efflux system protein 248899 1.29915615353722 2.9639169059649 1.04237570273075 1509 Lysine 2,3-aminomutase E lysine 2,3-aminomutase 248900 1.22877129373547 2.73669508738974 0.930180150075582 - - - Beta-lysine acetyltransferase 248901 1.26661379285282 2.92341661790051 1.03100885184918 - - - conserved protein 248902 1.31770414449412 3.1465152751566 1.10302628787637 2064 Flp pilus assembly protein TadC NU putative flagella related protein J 248903 1.26855360000687 2.92085421830148 1.02800241828468 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU putative flagella related protein FlaI 248904 1.29843947741766 3.07207331927538 1.05915277103562 467 RecA-superfamily ATPases implicated in signal transduction T putative flagella related protein H 248905 1.29542611171863 2.92596348040663 1.02198791925108 3894 Uncharacterized metal-binding protein R putative Flavoprotein 248906 1.30116085547593 2.98699109681064 1.04935643295927 15 Adenylosuccinate lyase F Adenylosuccinate lyase 248907 1.42652391348952 3.38425901649273 1.06967513197407 - - - hypothetical protein 248908 1.30932633619008 3.12811935453323 1.08539584809775 1646 Predicted phosphate-binding enzymes, TIM-barrel fold R geranylgeranylglyceryl diphosphate syntase 248909 1.28450036799931 2.97296805537885 1.05172122317505 1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase R methyl coenzyme M reductase system, component A2 248910 1.2639102436597 2.77495086787806 0.948036195347207 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 248911 1.27728099606163 2.87861249023815 0.994608282794861 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R putative NADPH-flavin oxidoreductase 248912 1.30899706903433 3.19585432914136 1.09536150971957 577 ABC-type antimicrobial peptide transport system, permease component V conserved protein 248913 1.31323736934819 3.03551938215828 1.066650073717 642 Signal transduction histidine kinase T Sensory transduction histidine kinases 248914 1.30409319467396 3.12058524899985 1.08118071016879 1361 S-layer domain M hypothetical protein 248915 1.33960674386867 3.14655487948217 1.04155331247522 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 248916 1.37039637525143 3.34725955885219 1.15247540911471 4591 ABC-type transport system, involved in lipoprotein release, permease component M ABC transporter, permease protein 248917 1.30846226871459 3.09358556817934 1.03382843913446 1361 S-layer domain M hypothetical protein 248918 1.34394608270329 3.20543617136457 1.06384252082125 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 248919 1.42222968561676 3.30674431402527 1.03505245400635 - - - hypothetical protein 248920 1.35042904651506 3.34174188566721 1.14392627417635 1682 ABC-type polysaccharide/polyol phosphate export systems, permease component GM ABC transporter, permease protein 248921 1.34979826405769 3.06746311827139 1.03767417351509 1131 ABC-type multidrug transport system, ATPase component V ABC transporter, ATP-binding protein 248922 1.31108116310946 3.22474390467744 1.08775483619474 4 Ammonia permease P Ammonium transporter 248923 1.23140638174162 2.71859955600133 0.915214697828166 347 Nitrogen regulatory protein PII E Nitrogen regulatory protein P-II 248924 1.31561870530349 3.16728195057633 1.05718463484853 - - - conserved protein 248925 1.27976954568145 2.84736488543349 0.979508966420543 71 Molecular chaperone (small heat shock protein) O putative small heat shock protein 248926 1.32867834205226 2.9807013478902 0.932845664012581 71 Molecular chaperone (small heat shock protein) O putative small heat shock protein 248927 1.2920112845656 2.76288957668756 0.984141663315002 5466 Predicted small metal-binding protein S conserved protein 248928 1.27692050313539 3.14174210046038 1.09625226900772 3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) T integral membrane protein 248929 1.26180603197689 2.84771908223415 0.978506267400516 174 Glutamine synthetase E Glutamine synthetase 248930 1.35715725777405 2.85082726726063 0.985122635005625 - - - hypothetical protein 248931 1.27578814658238 2.96534730428076 1.01837495038088 67 Glutamate synthase domain 1 E glutamate synthase, large chain 248932 1.29675710184476 3.07184053654712 1.04992713849266 69 Glutamate synthase domain 2 E glutamate synthase, large chain 248933 1.28948064264498 3.02605772826029 1.01595702167877 70 Glutamate synthase domain 3 E glutamate synthase, large chain 248934 1.3257845199928 3.13111221196929 1.06270092279751 1035 Coenzyme F420-reducing hydrogenase, beta subunit C Coenzyme F420 hydrogenase beta subunit 248935 1.29039894820414 2.99862422888882 1.01120831472374 - - - hypothetical protein 248936 1.35769640837214 3.05891949581217 0.95564236366784 - - - hypothetical protein 248937 1.42744289406725 3.58500940165742 1.11749107994651 - - - conserved protein 248938 1.33753420537509 3.03477511938208 0.967189262774495 - - - conserved protein 248939 1.3478540943811 3.10842172424999 1.0790835740087 6 Xaa-Pro aminopeptidase E Xaa-Pro aminopeptidase 248940 1.29803324664777 2.87923668956998 0.967089532617487 5423 Predicted metal-binding protein S conserved protein 248941 1.25881731082374 3.00565273561862 1.06679407072284 - - - putative protease 248942 1.33600862980748 3.05422375172344 1.03371145758943 2085 Predicted dinucleotide-binding enzymes R F420-dependent NADP reductase 248943 1.34118934713486 2.97891631687449 0.975708501849991 - - - hypothetical protein 248944 1.4017985272081 3.15628871523563 1.04121536161925 1150 Heterodisulfide reductase, subunit C C heterodisulfide reductase subunit HDRC 248945 1.29672448975109 2.90176018409644 1.02092265747666 2048 Heterodisulfide reductase, subunit B C heterodisulfide reductase subunit HDRB 248946 1.2693783935675 2.93640907151529 0.99814509066966 3543 Uncharacterized conserved protein S Iron-sulfur binding protein 248947 1.46955864706738 3.3582170655687 0.950318718898591 - - - Transposase 248948 1.30679318845295 2.98982647629222 1.01283999621264 4887 Uncharacterized metal-binding protein conserved in archaea R conserved protein 248949 1.24437043699479 2.82549198447759 0.987611552736486 2043 Uncharacterized protein conserved in archaea S conserved protein 248950 1.36101315022054 3.14265731700257 1.08915219084244 1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain C conserved protein 248951 1.28601156102526 2.95623833529927 1.03669679063966 1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain C conserved protein 248952 1.34010705046681 3.02740683383064 1.01165406543673 1433 Uncharacterized conserved protein S conserved protein 248953 1.35068735895088 3.41735246456211 1.15145983504704 1433 Uncharacterized conserved protein S conserved protein 248954 1.35136751901719 3.06334285381466 1.04241335383615 1342 Predicted DNA-binding proteins R HTH DNA-binding protein 248955 1.35091769142147 3.1578632548733 1.06104191962699 489 ATPases involved in chromosome partitioning D Nucleotide-binding protein 248956 1.23064190192128 2.80356558733008 0.977211738788139 3118 Thioredoxin domain-containing protein O Thiol-disulfide isomerase/thioredoxin 248957 1.26266171392657 3.18730969853028 1.10108963150719 785 Cytochrome c biogenesis protein O Cytochrome c-type biogenesis protein 248958 1.3670484940745 3.22749085503801 0.892956846393943 - - - conserved protein 248959 1.2822679848731 2.99391918890263 1.02689523801574 2082 Precorrin isomerase H Precorrin-8X methylmutase 248960 1.37097175527829 3.23759312179093 1.10936171564175 1010 Precorrin-3B methylase H Precorrin-3B C17-methyltransferase 248961 1.39966346814856 3.24673142862802 1.11366255118527 2073 Cobalamin biosynthesis protein CbiG H cobalamin biosynthesis protein G 248962 1.35731144358976 3.22777236463373 1.06053620959942 2073 Cobalamin biosynthesis protein CbiG H cobalamin biosynthesis protein G 248963 1.25759443056585 2.97616138059829 1.0249219918235 2875 Precorrin-4 methylase H Precorrin-4 C11-methyltransferase 248964 1.28748128039744 2.97466286699336 1.05101085007626 2243 Precorrin-2 methylase H Precorrin-2 C20-methyltransferase 248965 1.37329908540706 3.31514169005767 1.07614477424418 2242 Precorrin-6B methylase 2 H Precorrin-6Y C5,15-methyltransferase [decarboxylating] 248966 1.45126766770644 3.30065964880067 1.05062554655679 - - - hypothetical protein 248967 1.29086912616685 2.87677954671083 1.01556015361307 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase 248968 1.26584004178354 2.93993235452793 1.02344552830104 473 Isocitrate/isopropylmalate dehydrogenase CE Isocitrate dehydrogenase [NADP] 248969 1.28245516906223 2.89903133431157 1.00296463952199 1831 Predicted metal-dependent hydrolase (urease superfamily) R putative molybdenum cofactor biosynthesis protein 248970 1.39825643612225 3.07719140463741 1.00057607213389 1813 Predicted transcription factor, homolog of eukaryotic MBF1 K Zinc finger protein 248971 1.38600079344797 3.14546624225489 1.09834708079578 1222 ATP-dependent 26S proteasome regulatory subunit O 26S proteasome regulatory subunit RPT2/S4 248972 1.30405105360536 3.09598958414906 1.0678986546704 1628 Uncharacterized conserved protein S conserved protein 248973 1.29540111057358 3.11375380553091 1.08272590067692 206 Cell division GTPase D Cell division protein 248974 1.3848413678407 3.33424904204723 1.09032795433207 2443 Preprotein translocase subunit Sss1 U protein translocase subunit SecE 248975 1.30075244352922 3.01056225504467 1.06986386971073 250 Transcription antiterminator K putative transcription antitermination protein nusG 248976 1.30304215075273 2.9676010585046 1.03623350411567 80 Ribosomal protein L11 J LSU ribosomal protein L11P 248977 1.37212997235934 3.13580817234251 1.01747968390503 81 Ribosomal protein L1 J LSU ribosomal protein L1P 248978 1.27816121138966 2.87917752415125 0.992338520019037 244 Ribosomal protein L10 J LSU ribosomal protein L10P 248979 1.26002344311968 2.70733954604701 0.961796840561222 - - - LSU ribosomal protein L12AE 248980 1.31166451625312 2.89688002139889 1.01645977847428 535 Predicted Fe-S oxidoreductases R Molybdenum cofactor biosynthesis enzyme 248981 1.42665445350186 3.20989716154638 1.0031505630184 1444 Predicted P-loop ATPase fused to an acetyltransferase R putative ribosomal-protein-alanine acetyltransferase 248982 1.31029460186449 3.11513712464686 1.06594923188771 1912 Uncharacterized conserved protein S conserved protein 248983 1.26240311823305 2.89538582387361 0.975206765093447 4743 Predicted membrane protein S conserved protein 248984 1.34966486725345 2.9765337679243 1.01732334944872 1600 Uncharacterized Fe-S protein C Iron-sulfur cluster-binding protein 248985 1.3355955814918 2.91306918071461 0.988125400662105 350 Methylated DNA-protein cysteine methyltransferase L O6-methylguanine-DNA methyltransferase 248986 1.37647634015616 3.18549565441543 0.94861846924089 - - - hypothetical protein 248987 1.34570145234092 2.99560959847008 0.994000105980318 2834 Outer membrane lipoprotein-sorting protein M conserved protein 248988 1.33423659837935 2.96228025181347 1.0433811899696 - - - conserved protein 248989 1.30819031485914 2.97599841920525 1.01085079750817 2834 Outer membrane lipoprotein-sorting protein M conserved protein 248990 1.25064209561368 2.85575676231469 0.873190623810843 422 Thiamine biosynthesis protein ThiC H Thiamine biosynthesis protein 248991 1.29149801675633 2.98143888217927 1.05558610354769 463 Glycosyltransferases involved in cell wall biogenesis M Dolichol-phosphate mannosyltransferase 248992 1.29477952151679 3.03474757606729 1.06423365314991 2101 TATA-box binding protein (TBP), component of TFIID and TFIIIB K Transcription initiation factor TFIIB 248993 1.22563593633011 2.84560151252974 1.01806852772705 2101 TATA-box binding protein (TBP), component of TFIID and TFIIIB K Transcription initiation factor TFIIB 248994 1.33758823239582 3.10529120736581 1.05373025980986 1386 Predicted transcriptional regulator containing the HTH domain K hypothetical protein 248995 1.28903011307014 2.98446598333314 1.04588067462072 1354 Uncharacterized conserved protein S conserved protein 248996 1.30597775494169 2.879558935038 1.01474377596051 1196 Chromosome segregation ATPases D Chromosome partition protein 248997 1.36799775034604 3.16822050251037 1.07650986387636 - - - conserved protein 248998 1.30588091473612 3.18351141221493 1.11932684109878 370 Fe2+ transport system protein B P Ferrous iron transport protein B 248999 1.37508151604115 3.04387896167102 0.976476864794264 1321 Mn-dependent transcriptional regulator K Transcriptional repressor 249000 1.28005948419339 2.88154393527063 0.99221835166273 1246 N-acetylglutamate synthase and related acetyltransferases E Amino-acid acetyltransferase 249001 1.30625551556081 3.26826235680006 1.10231182451894 1268 Uncharacterized conserved protein R BioY protein 249002 1.30566112569387 3.01967244624015 1.02522940812532 1122 ABC-type cobalt transport system, ATPase component P Cobalt transporter, ATP-binding protein 249003 1.23464125467505 2.82831874406075 0.953973506451695 1122 ABC-type cobalt transport system, ATPase component P Cobalt transporter, ATP-binding protein 249004 1.37966127918203 3.34118046380219 1.15741852798784 619 ABC-type cobalt transport system, permease component CbiQ and related transporters P Cobalt transport protein 249005 1.3931827285321 3.04679855462768 1.04472815046919 640 Predicted transcriptional regulators K putative transcriptional regulator 249006 1.27281518563446 3.10634094061537 1.0767917470354 701 Predicted permeases R Transporter 249007 1.24419176072845 2.7457530359665 0.94717139931639 1983 Putative stress-responsive transcriptional regulator KT transcriptional regulator 249008 1.40576498481153 3.19189465294255 0.969671095132451 - - - Transposase 249009 1.43994496497845 3.13039752484016 0.980130405605463 - - - Transposase 249010 1.26620125280359 2.92484239997813 1.03114221060479 115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase EH Branched-chain amino acid aminotransferase 249011 1.31680733786535 3.09876293610625 1.08431657173121 303 Molybdopterin biosynthesis enzyme H Molybdopterin biosynthesis protein 249012 1.32572437839553 3.0438335633 1.05961069581315 1163 Predicted GTPase R GTP-binding protein 249013 1.28064320339191 2.96159710414992 1.04630395748768 1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes M D-alanine-D-alanine ligase related protein 249014 1.30769106763791 3.28229072297637 1.11234031483653 1055 Na+/H+ antiporter NhaD and related arsenite permeases P Arsenite permease 249015 1.36668599185961 3.01223338064855 0.999200082432375 - - - conserved protein 249016 1.43315488785303 3.09655545984189 0.988034047766424 - - - Chromosomal protein 249017 1.34172965684968 2.89706681340848 0.986106675802978 1598 Uncharacterized conserved protein S conserved protein 249018 1.28346214473613 2.92560103457168 1.03543850958205 4048 Uncharacterized protein conserved in archaea S putative sensory protein 249019 1.22586524941945 2.97946150684237 1.02033093919579 3420 Nitrous oxidase accessory protein P surface layer protein B 249020 1.37562706607414 3.2711764935406 1.07406916110916 5012 Predicted cobalamin binding protein R trimethylamine corrinoid protein 249021 1.32112793220149 3.22880872609853 1.12975743228918 1668 ABC-type Na+ efflux pump, permease component CP putative ATP-dependent Na+ efflux pump 249022 1.29890598095464 2.92673191774891 0.978229369486761 4152 ABC-type uncharacterized transport system, ATPase component R ABC transporter, ATP-binding protein 249023 1.31020502566608 3.06155772955788 1.04782348617599 1985 Pyrimidine reductase, riboflavin biosynthesis H 5-amino-6-(5-phosphoribosylamino)uracil reductase 249024 1.30530080379714 3.21213596998762 1.12581362278286 651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit CP Formate hydrogenlyase subunit 3 249025 1.304593187017 3.19854242983592 1.10858233089919 650 Formate hydrogenlyase subunit 4 C Formate hydrogenlyase subunit 4 249026 1.35755569214068 3.39792658294128 1.08910936083754 4237 Hydrogenase 4 membrane component (E) C Hydrogenase-4 component E 249027 1.30021215020266 3.13429528305693 1.07685448263768 651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit CP Hydrogenase-4 component F 249028 1.33298921723954 3.11960828706621 1.06848985407574 3261 Ni,Fe-hydrogenase III large subunit C Formate hydrogenlyase subunit 5 precursor 249029 1.28938947957829 2.98378809095635 0.990112019925829 3260 Ni,Fe-hydrogenase III small subunit C Formate hydrogenlyase subunit 7 249030 1.48157459803015 3.39457859812795 1.02941197928128 - - - hypothetical protein 249031 1.30491791283828 3.08973866983195 1.04789988842432 - - - hypothetical protein 249032 1.26101899102821 2.76893453465312 0.960249211468311 4742 Predicted transcriptional regulator K conserved protein 249033 1.26672212009928 2.78662751826757 0.970042932001267 2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains T Two-component response regulator 249034 1.30193687586772 3.05448375010718 1.08183429918527 474 Cation transport ATPase P Cation-transporting ATPase 249035 1.22052549775747 2.89950511652744 0.960583572592016 407 Uroporphyrinogen-III decarboxylase H Methylcobalamin: Coenzyme M methyltransferase 249036 1.27696564113209 2.8575468403223 1.01495254442747 3894 Uncharacterized metal-binding protein R conserved protein 249037 1.27285786555597 2.85428250951122 0.993941699107428 523 Putative GTPases (G3E family) R conserved protein 249038 1.28170950541543 2.8603632299641 0.974062195677454 5012 Predicted cobalamin binding protein R Methanol corrinoid protein 249039 1.24115171275583 2.80119575568135 0.870381185800595 - - - Methanol:corrinoid methyltransferase 249040 1.27051782940708 3.23032213516212 1.10839665355892 1584 Predicted membrane protein S putative regulatory protein 249041 1.28069790392417 3.01229132980052 1.03906611856077 53 Predicted Co/Zn/Cd cation transporters P Cation efflux system protein 249042 1.29265728674163 3.02929449081567 1.07449162025769 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ conserved protein 249043 1.30139866714151 3.02171120964426 1.05933079051836 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ conserved protein 249044 1.30968500644653 2.98112253261649 1.00317183035996 4742 Predicted transcriptional regulator K conserved protein 249045 1.25664263273684 2.88046200187078 0.976630257891725 4742 Predicted transcriptional regulator K conserved protein 249046 1.24785004386172 2.906141922738 1.03482839937813 - - - conserved protein 249047 1.26065557273267 2.87395975609767 0.996966412682899 12 Predicted GTPase, probable translation factor J GTP-binding protein 249048 1.27504972680511 2.9062394307071 1.00336179743755 20 Undecaprenyl pyrophosphate synthase I Undecaprenyl pyrophosphate synthetase 249049 1.31814566694195 2.94333509369083 0.993549360175524 - - - hypothetical protein 249050 1.31559828208402 3.03440627907449 1.04285752889763 1693 Uncharacterized protein conserved in archaea S conserved protein 249051 1.34465945643458 3.08244061794443 1.0552971348882 1237 Metal-dependent hydrolases of the beta-lactamase superfamily II R metal dependent hydrolase 249052 1.35424731188875 3.07415693263982 1.03459747977749 396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component O ABC transporter, ATP-binding protein 249053 1.29022701651249 2.94921786947874 1.03444892249986 719 ABC-type transport system involved in Fe-S cluster assembly, permease component O ABC transporter, ATP-binding protein 249054 1.46583779033045 3.41009119721567 1.07604631364446 467 RecA-superfamily ATPases implicated in signal transduction T putative DNA integration/recombination/invertion protein 249055 1.37345899396084 3.20469060733161 1.08344009279457 467 RecA-superfamily ATPases implicated in signal transduction T putative DNA integration/recombination/invertion protein 249056 1.56249217081268 3.56409055829338 1.11755597980815 - - - thiol-disulfide isomerase 249057 1.31609743295998 2.90422042746337 0.956628936840209 - - - thiol-disulfide isomerase 249058 1.39014947875304 3.11359603858249 1.07433498838136 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 249059 1.24527972266032 2.69985022908353 0.979519105666435 3355 Predicted transcriptional regulator K putative transcriptional regulator 249060 1.26186483665307 2.93829839842711 1.00173665728963 348 Polyferredoxin C Iron-sulfur-binding protein 249061 1.27279414713958 2.9288452881552 0.981665831651666 459 Chaperonin GroEL (HSP60 family) O Thermosome, alpha subunit 249062 1.3300100375051 3.1633926128837 1.09522807704789 1935 Uncharacterized conserved protein S conserved protein 249063 1.3040273026626 3.10196240918015 1.0374389825486 1938 Archaeal enzymes of ATP-grasp superfamily R conserved protein 249064 1.220842243483 2.99212201036917 0.883668481824374 - - - hypothetical protein 249065 1.27002776021947 2.9652221533542 1.04072128159378 1751 Uncharacterized conserved protein S hypothetical protein 249066 1.2989817240299 2.94951862152689 1.03842085124643 343 Queuine/archaeosine tRNA-ribosyltransferase J Archaeosine tRNA-ribosyltransferase 249067 1.63050354900553 3.77659143546568 1.09222007198524 - - - hypothetical protein 249068 1.32199194450517 3.31054458323457 1.14334815125185 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H hypothetical protein 249069 1.29996819857114 2.95782061850589 1.03405380956751 644 Dehydrogenases (flavoproteins) C oxidoreductase 249070 1.25152885714324 2.8557789664938 0.999524530653925 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 249071 1.29650222563372 2.67032724616644 0.92143658022464 1340 Uncharacterized archaeal coiled-coil protein S putative phosphoserine phosphatase 249072 1.34677997117166 3.08592249957789 1.05151361770536 560 Phosphoserine phosphatase E putative phosphoserine phosphatase 249073 1.28709781103367 2.85444251990679 0.996567706650495 1927 Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase C F420-dependent methylenetetrahydromethanopterin dehydrogenase 249074 1.28174508471937 3.07990047412396 1.02602883140182 4048 Uncharacterized protein conserved in archaea S conserved protein 249075 1.30767338246909 3.00454429817664 1.0366776052362 1810 Uncharacterized protein conserved in archaea S conserved protein 249076 1.3010532171201 2.92026467365346 0.983797031489567 125 Thymidylate kinase F Thymidylate kinase 249077 1.41736312357994 3.19927966293269 1.04639077797898 - - - conserved protein 249078 1.34871486483823 3.26416485169254 1.10397180181357 1411 Uncharacterized protein related to proFAR isomerase (HisA) R Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 249079 1.3165556132788 3.09022273265721 1.04102889187922 1891 Uncharacterized protein conserved in archaea S conserved protein 249080 1.33227268595386 3.15430408958012 1.06846947833086 - - - conserved protein 249081 1.3287597469178 3.24152663680432 1.14327515741091 - - - hypothetical protein 249082 1.30385212229549 3.04513635902993 1.02789229638098 726 Predicted xylanase/chitin deacetylase G Polysaccharide deacetylase 249083 1.29867044299466 3.09658465179251 1.07657809636733 - - - conserved protein 249084 1.25930687329173 2.90538284955899 1.01148409312436 - - - conserved protein 249085 1.27788668930173 2.92306088694648 1.01456487588176 - - - conserved protein 249086 1.36457679430733 3.28423197292866 1.1491971249625 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase 249087 1.28526079806626 3.01286826256185 1.04254087131465 673 Predicted dehydrogenases and related proteins R oxidoreductase 249088 1.30089376232536 3.13563889768164 1.09619483638948 - - - hypothetical protein 249089 1.27644736388554 3.14443736187355 1.082540683737 2244 Membrane protein involved in the export of O-antigen and teichoic acid R O-antigen translocase 249090 1.30633384953176 2.98373922952203 1.0036605754284 5653 Protein involved in cellulose biosynthesis (CelD) M conserved protein 249091 1.33059087267392 3.18012520274212 1.11936717614828 438 Glycosyltransferase M glycosyltransferase 249092 1.2861646401602 2.97182223941363 1.01389224736576 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase 249093 1.28929392644921 2.89715911247279 0.981782981340308 - - - conserved protein 249094 1.33835949299695 3.02676142587516 1.03864741958258 1817 Uncharacterized protein conserved in archaea S conserved protein 249095 1.38462382553129 3.26325114011077 1.10608602506221 - - - hypothetical protein 249096 1.2842802526035 3.13109594475305 1.02264518801396 - - - hypothetical protein 249097 1.24988542583245 2.83650280726184 0.973216122555495 1004 Predicted UDP-glucose 6-dehydrogenase M UDP-glucose 6-dehydrogenase 249098 1.26832036511032 2.85593072985903 1.01568443268601 1210 UDP-glucose pyrophosphorylase M UTP--glucose-1-phosphate uridylyltransferase 249099 1.28861189916389 2.99330754065624 1.04562368693642 451 Nucleoside-diphosphate-sugar epimerases MG UDP-glucose 4-epimerase 249100 1.29469606937728 3.17267581470849 1.07421174262518 2244 Membrane protein involved in the export of O-antigen and teichoic acid R Transporter 249101 1.24235015269652 2.93882707972681 1.02992435689716 - - - conserved protein 249102 1.31019099109232 3.05352223483853 1.03806224500676 438 Glycosyltransferase M glycosyltransferase 249103 1.24210839112526 2.85859591135047 1.00876637109872 438 Glycosyltransferase M glycosyltransferase 249104 1.32817977166285 3.12494447581185 1.05477303675509 1215 Glycosyltransferases, probably involved in cell wall biogenesis M Dolichyl-phosphate mannose synthase related protein 249105 1.32896797133988 3.10373674486551 1.0206980643458 463 Glycosyltransferases involved in cell wall biogenesis M Dolichyl-phosphate mannose synthase related protein 249106 1.35109266988814 3.15381542887866 0.974936353653816 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyltransferase 249107 1.32849942116903 3.08932281193175 0.949664786764106 438 Glycosyltransferase M glycosyltransferase 249108 1.37022301817193 3.21665480418604 1.01677400212661 438 Glycosyltransferase M glycosyltransferase 249109 1.24522767256584 2.89896313942278 1.02025246249327 - - - conserved protein 249110 1.24423738101132 2.92380944172244 1.01409306787103 - - - conserved protein 249111 1.35858959220942 3.31842400965019 1.08190297613439 4906 Predicted membrane protein S conserved protein 249112 1.33237329642069 3.11972808244025 1.02033991170699 463 Glycosyltransferases involved in cell wall biogenesis M Dolichol-phosphate mannosyltransferase 249113 1.2553093338261 2.95717981481553 1.01325009261046 4743 Predicted membrane protein S conserved protein 249114 1.35212509775754 3.24834485771229 1.10661218014871 - - - hypothetical protein 249115 1.49312645966588 3.82631923816867 1.18541537817078 - - - conserved protein 249116 1.29122795880956 3.01620936955067 1.06206821175496 1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase M Acetyltransferase 249117 1.22298255643524 2.78586445365351 0.975757019399644 399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogen M Aspartate aminotransferase 249118 1.28897046781294 2.96652146750603 0.981534550762632 673 Predicted dehydrogenases and related proteins R Myo-inositol 2-dehydrogenase 249119 1.24392175127899 2.89164229831226 1.01907880565755 677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase M NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase 249120 1.28678509129971 2.84266624995734 0.989664756501502 - - - conserved protein 249121 1.32145472983229 3.27608701121497 1.13325849191132 2244 Membrane protein involved in the export of O-antigen and teichoic acid R O-antigen translocase 249122 1.31006734862666 3.08361350477671 1.02501314621202 - - - conserved protein 249123 1.2356294877746 2.85393691870285 1.01272568178614 - - - conserved protein 249124 1.32188445660236 3.02844654488377 1.02006028291353 1254 Acylphosphatases C hypothetical protein 249125 1.43299643542926 3.30793588149589 1.03535198646237 1708 Predicted nucleotidyltransferases R nucleotidyltransferase 249126 1.29014384157269 2.90109734582646 0.993122177376085 2445 Uncharacterized conserved protein S conserved protein 249127 1.3002059105294 3.03095290134093 1.01602500011292 451 Nucleoside-diphosphate-sugar epimerases MG UDP-N-acetylglucosamine 4-epimerase 249128 1.34673724452006 3.08515882304864 1.03952666631815 1669 Predicted nucleotidyltransferases R nucleotidyltransferase 249129 1.53352247379692 3.51854495839932 1.08274070891564 2361 Uncharacterized conserved protein S hypothetical nucleotidyltransferase 249130 1.37259906143793 3.35002264238758 1.0995058563971 463 Glycosyltransferases involved in cell wall biogenesis M Dolichyl-phosphate mannose synthase related protein 249131 1.27626550832969 2.82548155502507 0.96585456557386 1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes M dTDP-4-dehydrorhamnose 3,5-epimerase 249132 1.2569226808721 2.90878590493449 0.978938924166227 1088 dTDP-D-glucose 4,6-dehydratase M dTDP-glucose 4,6-dehydratase 249133 1.24137220869112 2.8431927671266 0.994220355584167 1091 dTDP-4-dehydrorhamnose reductase M dTDP-4-dehydrorhamnose reductase 249134 1.38887543891544 3.19299959038745 1.07761141798089 1209 dTDP-glucose pyrophosphorylase M Glucose-1-phosphate thymidylyltransferase 249135 1.3047090105921 2.92891763120443 1.0148542907515 381 UDP-N-acetylglucosamine 2-epimerase M UDP-N-acetylglucosamine 2-epimerase 249136 1.41056452450163 3.30074107977765 0.893759422764966 1835 Predicted acyltransferases I conserved protein 249137 1.30778958274094 2.97412919612482 1.04801404098643 677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase M UDP-N-acetyl-D-mannosamine 6-dehydrogenase 249138 1.52403729403034 3.36955023526736 0.986490889424936 - - - conserved protein 249139 1.48600068365772 3.55772982013165 1.01455869114479 - - - hypothetical protein 249140 1.43423878986934 3.60884284928493 1.06234740680034 2244 Membrane protein involved in the export of O-antigen and teichoic acid R oligosaccharide repeat unit transporter 249141 1.38198883818119 3.3769345569934 0.961452959959424 4906 Predicted membrane protein S Conserved transmembrane protein 249142 1.3891044071525 3.13986534341947 0.884427553824208 438 Glycosyltransferase M glycosyltransferase 249143 1.36283480368794 3.10956569064772 0.960423425896514 438 Glycosyltransferase M glycosyltransferase 249144 1.37527487599681 3.15101089449304 0.962306160586694 438 Glycosyltransferase M glycosyltransferase 249145 1.30899518888345 3.05091530526388 1.06596117288672 673 Predicted dehydrogenases and related proteins R oxidoreductase 249146 1.26004167185228 2.89225760877491 0.991158011525065 - - - conserved protein 249147 1.30841608828258 3.01676190493866 1.02868328195049 438 Glycosyltransferase M glycosyltransferase 249148 1.38616908941539 3.35160514673117 1.08579363717478 463 Glycosyltransferases involved in cell wall biogenesis M Dolichyl-phosphate mannose synthase related protein 249149 1.30073013183523 3.11250102379639 1.05716960113142 463 Glycosyltransferases involved in cell wall biogenesis M Dolichyl-phosphate mannose synthase related protein 249150 1.28581558278195 3.10179506171037 1.05281864913576 4743 Predicted membrane protein S conserved protein 249151 1.28919007107805 2.99598811420565 1.04334875257946 1266 Predicted metal-dependent membrane protease R conserved protein 249152 1.38992300911048 3.58887691102626 1.0856448587342 - - - hypothetical protein 249153 1.3745208385922 3.62470557620851 1.21415556643836 - - - conserved protein 249154 1.34698864251836 3.16768029934883 1.07555411048202 - - - conserved protein 249155 1.27181510087191 2.89514967913119 1.02154625861587 - - - conserved protein 249156 1.25974878572344 3.18422866170574 1.13556412276966 - - - dTDP-glucose 4,6-dehydratase 249157 1.32068301885285 2.90119796358567 0.978330503087314 5421 Transposase L Transposase 249158 1.2736765149272 2.92152592977511 0.999205765633033 451 Nucleoside-diphosphate-sugar epimerases MG dTDP-glucose 4,6-dehydratase 249159 1.29731492389244 3.12721006899916 1.08595374304932 4743 Predicted membrane protein S conserved protein 249160 1.3331514848256 3.19638416671258 1.07400925764395 - - - conserved protein 249161 1.30223721862734 2.99149007872057 1.04069664211446 - - - conserved protein 249162 1.35360616362791 3.24975271599382 1.12644731534631 3503 Predicted membrane protein S conserved protein 249163 1.42243477699682 3.06997179149245 0.901317253036258 - - - Transposase 249164 1.31616895804787 3.10767642966421 1.05942423026215 - - - conserved protein 249165 1.21929594112933 2.79193379170536 1.03053806993889 1383 Ribosomal protein S17E J SSU ribosomal protein S17E 249166 1.26553435749523 2.97777672833389 1.05072772046285 329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase EM Dihydrodipicolinate synthase 249167 1.27132326623904 2.94977742592557 0.967039788424027 289 Dihydrodipicolinate reductase E Dihydrodipicolinate reductase 249168 1.3498898957699 3.17066634902476 1.05215667471004 - - - conserved protein 249169 1.39785047527523 3.03998719787169 0.982510559473983 - - - conserved protein 249170 1.3213907927108 3.11680498160831 1.0528305520609 - - - conserved protein 249171 1.33828269212874 2.98876331950347 0.974853001353448 - - - conserved protein 249172 1.37173763414108 3.04311140523931 1.02605421418084 - - - conserved protein 249173 1.4163991454846 3.30858860968881 1.10392327042778 - - - conserved protein 249174 1.35073905423448 3.06810919478398 1.00978805693702 - - - conserved protein 249175 1.38101613534354 3.11742075178118 1.05898068198516 - - - conserved protein 249176 1.30505000763875 2.74292126800011 0.95142853883153 - - - conserved protein 249177 1.34453171631709 3.20570096991977 1.07232514383634 1781 Aspartate carbamoyltransferase, regulatory subunit F Aspartate carbamoyltransferase, regulatory subunit 249178 1.34129277771363 3.13114603542719 1.07181515842084 540 Aspartate carbamoyltransferase, catalytic chain F Aspartate carbamoyltransferase, catalytic subunit 249179 1.43923492380483 2.98315177108941 1.00163421891951 - - - conserved protein 249180 1.2950510958953 3.04270751127058 1.05902128332574 269 3-hexulose-6-phosphate synthase and related proteins G hexulose-6-phosphate synthase 249181 1.25875864885119 2.91854964387025 0.983669529802374 - - - conserved protein 249182 1.32928498477689 3.01638122774153 1.06284960974067 514 Superfamily II DNA helicase L ATP-dependent DNA helicase 249183 1.30790065611019 2.95601356636313 1.01167494431777 519 GMP synthase, PP-ATPase domain/subunit F GMP synthase [glutamine-hydrolyzing] 249184 1.30593635498066 2.99089127537459 0.981167654759867 1244 Predicted Fe-S oxidoreductase R Fe-S oxidoreductase 249185 1.28937554770941 3.04701555170447 1.03379626806349 548 Acetylglutamate kinase E Acetylglutamate kinase 249186 1.33164406122061 2.88706029268326 1.00945119524124 - - - Chromosomal protein 249187 1.27686915588376 2.90532439736789 1.0060329292407 1469 Uncharacterized conserved protein S conserved protein 249188 1.36383886615367 2.90143965843947 0.973204990734229 4014 Uncharacterized protein conserved in archaea S conserved protein 249189 1.30412918915207 3.06513837801852 1.07478685303017 4065 Uncharacterized protein conserved in archaea S conserved protein 249190 1.26945730321787 2.88223413525216 0.967384768032519 1035 Coenzyme F420-reducing hydrogenase, beta subunit C Coenzyme F420 hydrogenase, beta subunit 249191 1.29768474739523 2.76462121531188 0.997597002413768 721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit J Glutamyl-tRNA(Gln) amidotransferase, subunit C 249192 1.27502658823079 2.99809866919342 1.05276621228086 154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases J Glutamyl-tRNA(Gln) amidotransferase, subunit A 249193 1.28259361760357 2.89073291716967 1.00591278543768 64 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) J Glutamyl-tRNA(Gln) amidotransferase, subunit B 249194 1.3257211984036 3.03197562737095 1.04387486064112 388 Predicted amidohydrolase R Nitrilase 249195 1.29496003351765 2.9515389943366 1.01201755212619 - - - hypothetical protein 249196 1.3396502857124 2.9925430134617 1.02979906163293 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H SAM-dependent methyltransferases 249197 1.38725355434147 3.22613441724997 1.11188842289199 - - - conserved protein 249198 1.29218446473122 2.91635447178213 0.937759374817242 - - - hypothetical protein 249199 1.38692154714672 3.08127926682031 1.00799076185777 262 Dihydrofolate reductase H conserved protein 249200 1.32232943278492 2.95530310646199 0.999719435646058 1715 Restriction endonuclease V 5-methylcytosine-specific restriction enzyme 249201 1.30096687919866 3.08816249889389 1.08651898912846 501 Zn-dependent protease with chaperone function O protease HTPX 249202 1.25868126311998 2.83845621019627 0.998551496042061 207 Thymidylate synthase F Thymidylate synthase 249203 1.30803541837931 3.1816338379977 1.09134299611167 128 5-enolpyruvylshikimate-3-phosphate synthase E 3-phosphoshikimate 1-carboxyvinyltransferase 249204 1.28628507043313 2.86946789077685 0.90191650416707 1092 Predicted SAM-dependent methyltransferases R methyltransferase 249205 1.27623104278254 2.88921986853419 0.800050030590404 4058 Methyl coenzyme M reductase, alpha subunit H Methyl-coenzyme M reductase, alpha subunit 249206 1.31693832959623 3.01035257244741 0.920157502978653 4057 Methyl coenzyme M reductase, gamma subunit H Methyl-coenzyme M reductase, gamma subunit 249207 1.35499973285628 3.21264667244219 1.06511582562958 4056 Methyl coenzyme M reductase, subunit C H Methyl-coenzyme M reductase operon protein C 249208 1.31971818645991 2.94889510772464 1.02301734202149 4055 Methyl coenzyme M reductase, subunit D H Methyl-coenzyme M reductase operon protein D 249209 1.27281218183811 3.03910968714335 0.936642034014634 4054 Methyl coenzyme M reductase, beta subunit H Methyl-coenzyme M reductase, beta subunit 249210 1.26722764846612 2.94990821094607 1.05673806319346 1625 Fe-S oxidoreductase, related to NifB/MoaA family C conserved protein 249211 1.33923686364904 3.05472059012335 1.06728082639933 1933 Archaeal DNA polymerase II, large subunit L DNA polymerase II large subunit 249212 1.48725481456255 3.40650073461786 1.08934244718922 - - - conserved protein 249213 1.34451385748646 3.17210984496689 1.10144959655435 9 Putative translation factor (SUA5) J SUA5 protein 249214 1.31518670549237 2.99127687461693 1.04855270332953 1850 Ribulose 1,5-bisphosphate carboxylase, large subunit G Ribulose bisphosphate carboxylase large chain 249215 1.33791729922086 3.27442282801267 1.12632957676953 4756 Predicted cation transporter R Cation transporter 249216 1.30258186385411 3.17396461367808 1.08162630196204 4756 Predicted cation transporter R Cation transporter 249217 1.31709141824967 3.21621604608404 1.04985488609896 4756 Predicted cation transporter R conserved protein 249218 1.31559768286852 3.19347308895969 1.05812037684945 4756 Predicted cation transporter R Cation transporter 249219 1.25546161012391 2.72473554884327 0.908727618089657 71 Molecular chaperone (small heat shock protein) O putative heat shock protein 249220 1.34447461142219 3.00841519374022 1.03398942607878 71 Molecular chaperone (small heat shock protein) O putative heat shock protein 249221 1.32846705226457 3.02088951672881 1.05061110902443 464 ATPases of the AAA+ class O CdcH protein 249222 1.33805490407033 2.95766760398349 1.00545231456778 1777 Predicted transcriptional regulators K transcriptional regulator, ArsR family 249223 1.27556128931063 3.00248077396016 1.00143579120712 - - - conserved protein 249224 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 249225 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 249226 1.32572885017165 2.90916153545385 1.02226029401751 3364 Zn-ribbon containing protein R conserved protein 249227 1.3266029137243 3.12029696383081 1.00709774628425 2236 Predicted phosphoribosyltransferases R Xanthine-guanine phosphoribosyltransferase 249228 1.29393861763316 2.81569280909192 0.944009552539002 4742 Predicted transcriptional regulator K conserved protein 249229 1.2657743736222 2.89701857200603 0.995459901002232 - - - hypothetical protein 249230 1.31821938820914 3.00182243998072 1.0276392503346 5513 Predicted secreted protein S hypothetical protein 249231 1.2871514348378 2.8262902562138 0.982709574716421 - - - conserved protein 249232 1.33201705009854 2.97204054294 1.04298779231035 541 Signal recognition particle GTPase U signal recognition particle subunit FFH/SRP54 249233 1.43386457830844 3.21107513096808 0.963450323315486 - - - hypothetical protein 249234 1.49536388137544 3.2790781489042 0.949150086775538 - - - conserved protein 249235 1.27263359785421 2.85633733182413 1.02696122603384 518 GMP synthase - Glutamine amidotransferase domain F GMP synthase [glutamine-hydrolyzing] 249236 1.23565518552721 2.92447677008309 0.99574554409193 1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes G 2-dehydro-3-desoxyphosphoheptanote aldolase 249237 1.25836834322912 2.91146320509624 1.00913669401357 1465 Predicted alternative 3-dehydroquinate synthase E 3-dehydroquinate synthase 249238 1.29571399698701 3.0347215759018 1.03022389345979 710 3-dehydroquinate dehydratase E 3-dehydroquinate dehydratase 249239 1.27214553113959 2.99531851256899 1.04431415037802 169 Shikimate 5-dehydrogenase E Shikimate 5-dehydrogenase 249240 1.31988569901283 3.06294248299893 1.06746456453105 287 Prephenate dehydrogenase E Prephenate dehydrogenase 249241 1.28848889202457 2.96888800626143 0.988339607631913 1413 FOG: HEAT repeat C hypothetical protein 249242 1.3453174874663 3.0912813068506 1.06467896407614 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H methyltransferase 249243 1.2989460647768 3.11860468342608 1.07283820546431 149 Triosephosphate isomerase G Triosephosphate isomerase 249244 1.26070021697049 2.91628910804095 0.984784304105853 1795 Uncharacterized conserved protein S conserved protein 249245 1.37521868627845 3.11159515533208 1.03622287831708 177 Predicted EndoIII-related endonuclease L Endonuclease III 249246 1.42188205612079 3.59375571795852 1.15250194846109 2881 Uncharacterized protein conserved in archaea S conserved protein 249247 1.48617556635895 3.2295192411038 0.983537779306948 - - - conserved protein 249248 1.44023027676555 3.07699616902725 1.0037914511748 2193 Bacterioferritin (cytochrome b1) P Bacterioferritin 249249 1.26851007849708 2.95381283547261 1.04347577699801 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase 249250 1.26164535208333 2.83040980502741 0.984436508222218 84 Mg-dependent DNase L Sec-independent transport protein TatD 249251 1.22087691728644 2.83865378508915 0.969713818404565 491 Zn-dependent hydrolases, including glyoxylases R hypothetical protein 249252 1.30373366935018 2.90460924391537 1.02883860073534 1032 Fe-S oxidoreductase C Fe-S oxidoreductase 249253 1.30817949679337 2.90783504115201 0.967895945977361 - - - conserved protein 249254 1.32865170034131 3.07086050192071 1.04379989523622 - - - conserved protein 249255 1.34513392668348 3.06776996070061 1.06743553826358 247 Fe-S oxidoreductase C Fe-S oxidoreductase 249256 1.33811709219271 3.19724864385071 1.11574585663599 277 FAD/FMN-containing dehydrogenases C (S)-2-hydroxy-acid dehydrogenase 249257 1.36549997641169 3.14812525007676 1.100796300306 1549 Queuine tRNA-ribosyltransferases, contain PUA domain J Archaeosine tRNA-ribosyltransferase 249258 1.34207781177925 2.99940125020049 0.987612467016338 456 Acetyltransferases R Acetyltransferase 249259 1.42075917042127 3.18238436998277 1.02799175369178 1745 Predicted metal-binding protein R conserved protein 249260 1.31188643109245 3.01674950727234 1.0284385467254 358 DNA primase (bacterial type) L DNA primase 249261 1.28719730644454 3.065057956425 1.06032559972244 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R NADH oxidase 249262 1.3446725428798 3.13901865541647 1.08857462313903 430 RNA 3'-terminal phosphate cyclase A RNA 3'-terminal phosphate cyclase 249263 1.26552674407208 2.83981993745429 0.944823477669766 1859 RNA:NAD 2'-phosphotransferase J putative tRNA 2'phosphotransferase 249264 1.2426876610205 2.82871796591086 0.97392283340892 1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-bin L Replication factor-A protein 249265 1.36539825456358 3.05019792056709 1.01198927807827 5421 Transposase L Transposase 249266 1.2783744891456 3.02956877835723 1.03507870449336 2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains T conserved protein 249267 1.3300978523402 3.19889909082561 1.08519791786295 3448 CBS-domain-containing membrane protein T conserved protein 249268 1.31086079039976 3.09203498991052 1.04968779347658 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K conserved protein 249269 1.30835805836072 3.13900008062623 1.08909125015484 3448 CBS-domain-containing membrane protein T conserved protein 249270 1.34801589788618 3.18732199828825 1.10146611704709 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K conserved protein 249271 1.3381707833721 3.13257245748575 1.017189068211 2013 Uncharacterized conserved protein S HTH DNA-binding protein 249272 1.299456909858 2.81145411420143 0.975646749191661 1423 ATP-dependent DNA ligase, homolog of eukaryotic ligase III L conserved protein 249273 1.35039193021318 2.91333451141076 0.938611149943379 3666 Transposase and inactivated derivatives L Transposase 249274 1.25571381150795 2.90412443011822 0.997832613936954 3276 Selenocysteine-specific translation elongation factor J protein translation elongation factor 1A 249275 1.29591481685812 2.91802778917005 1.02619863065904 2105 Uncharacterized conserved protein S hypothetical protein 249276 1.31654335120914 3.03636240758976 1.02780935645801 1082 Sugar phosphate isomerases/epimerases G conserved protein 249277 1.27970467521914 3.05310543375147 1.04450858330918 1931 Uncharacterized protein conserved in archaea S conserved protein 249278 1.36493851400781 3.18910774017414 1.03223102241854 237 Dephospho-CoA kinase H UMP/CMP kinase related protein 249279 1.27195958837166 2.92651230823087 1.0178326928486 1474 Cdc6-related protein, AAA superfamily ATPase LO origin recognition complex subunit 249280 1.45097378586698 3.63175640052973 1.13636366523265 591 Na+/proline symporter ER sodium/proline symporter 249281 1.30255803508051 3.1578519121639 1.07797672687569 591 Na+/proline symporter ER sodium/proline symporter 249282 1.31159147421227 3.08343682584039 1.07909024124868 76 Glutamate decarboxylase and related PLP-dependent proteins E glutamate decarboxylase 249283 1.28239517287182 3.15529903604617 1.08132936286865 1994 Zn-dependent proteases R conserved protein 249284 1.32968810898339 3.19067150472222 1.11638953654278 1916 Uncharacterized homolog of PrgY (pheromone shutdown protein) S Pheromone shutdown protein 249285 1.32785192974971 2.94609989628539 0.978443829820959 - - - conserved protein 249286 1.25430337777938 2.82871317836701 0.971248450816752 2037 Formylmethanofuran:tetrahydromethanopterin formyltransferase C Formylmethanofuran--tetrahydromethanopterin formyltransferase 249287 1.34027498677609 3.15983969371577 1.00937639962019 1871 Chemotaxis protein; stimulates methylation of MCP proteins NT Chemotaxis protein 249288 1.33315762197827 3.22608404232016 1.03354031657153 1776 Chemotaxis protein CheC, inhibitor of MCP methylation NT Chemotaxis protein 249289 1.35703618881413 3.00814118650352 1.00882800297652 1352 Methylase of chemotaxis methyl-accepting proteins NT chemotaxis protein methyltransferase 249290 1.34045728379309 2.92415172422226 0.993039163819918 643 Chemotaxis protein histidine kinase and related kinases NT Chemotaxis protein 249291 1.30603735307274 3.05818362181168 1.05958198596766 2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain NT protein-glutamate methylesterase 249292 1.35182351240811 3.09799703177325 0.98794793548943 2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain TK Chemotaxis protein 249293 1.23654249817256 2.80330214198716 0.952306478539981 3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain KT Two-component response regulator 249294 1.31122809576878 2.99753821783984 1.05924872668428 840 Methyl-accepting chemotaxis protein NT Methyl-accepting chemotaxis protein 249295 1.26230468009576 3.34851013479852 1.07866174105692 835 Chemotaxis signal transduction protein NT Chemotaxis protein CheW 249296 1.29112413207669 3.19860760415021 1.11380721467694 2610 H+/gluconate symporter and related permeases GE Gluconate permease 249297 1.2851238878863 2.96692274552292 0.992063458863649 1321 Mn-dependent transcriptional regulator K Iron-dependent repressor 249298 1.23593264532819 2.7992575989491 0.928153332523231 803 ABC-type metal ion transport system, periplasmic component/surface adhesin P Zinc ABC transporter, zinc-binding protein 249299 1.30862253843108 2.94646934325578 0.999589688085914 1121 ABC-type Mn/Zn transport systems, ATPase component P Zinc ABC transporter, ATP-binding protein 249300 1.30281257722463 3.23594346429531 1.0974243256362 1108 ABC-type Mn2+/Zn2+ transport systems, permease components P Zinc ABC transporter, permease protein 249301 1.31255033488807 2.8853843036441 0.958831991117416 - - - hypothetical protein 249302 1.37175598710366 3.22849219364394 1.10355203748765 - - - hypothetical protein 249303 1.27288599558153 2.99097342363964 1.03643462730969 - - - hypothetical protein 249304 1.28825711593057 2.98552265048814 1.03351024724354 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C pyruvate synthase beta subunit 249305 1.29602487596173 2.97394980306279 1.03133989690109 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C pyruvate synthase alpha subunit 249306 1.30970535631484 2.82095610633742 0.958506994821615 1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit C pyruvate synthase delta subunit 249307 1.31371024647837 3.04105939015128 1.06674116241983 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C pyruvate synthase gamma subunit 249308 1.29909133555722 3.00651567544693 1.0504683435049 42 tRNA-dihydrouridine synthase J NifR3-like protein 249309 1.25463562914637 2.90623222154082 0.96414126459798 681 Signal peptidase I U signal sequence peptidase 249310 1.29979551484451 3.16941051782852 1.09811680076737 1311 Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B L DNA polymerase II small subunit 249311 1.33893160568987 2.99901520386412 1.02633154699931 731 Fe-S oxidoreductases C Fe-S oxidoreductase 249312 1.29283851462464 2.93187112880241 1.02159774621235 1503 Peptide chain release factor 1 (eRF1) J Peptide Chain Release Factor 249313 1.33709081152027 3.06310631409884 1.06290021745293 18 Arginyl-tRNA synthetase J Arginyl-tRNA synthetase 249314 1.30150967945771 2.77770863968146 0.995543306954722 - - - hypothetical protein 249315 1.31560659547656 3.00088114932451 1.05620035317538 - - - conserved protein 249316 1.30052071617576 2.90088433986008 1.00479176698037 367 Asparagine synthase (glutamine-hydrolyzing) E conserved protein 249317 1.33586837142704 2.95561770465957 1.00215892874766 620 Methionine synthase II (cobalamin-independent) E 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 249318 1.26221864130142 2.83452063254116 0.985432256835891 620 Methionine synthase II (cobalamin-independent) E 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 249319 1.40727338304896 3.15437037695902 1.07852127921717 - - - conserved protein 249320 1.27502532403392 2.93487728937777 1.02657346013061 3269 Predicted RNA-binding protein, contains TRAM domain R conserved protein 249321 1.32357732744329 3.03494053156092 0.996193642972479 3269 Predicted RNA-binding protein, contains TRAM domain R conserved protein 249322 1.28234925597346 2.95592136131226 1.00601546660686 3269 Predicted RNA-binding protein, contains TRAM domain R conserved protein 249323 1.23792876297289 2.85438758674888 0.986987853192504 3269 Predicted RNA-binding protein, contains TRAM domain R putative methyltransferase 249324 1.25777684245093 3.01815977784459 1.04012742187436 - - - hypothetical protein 249325 1.29057511027674 2.97418711510767 1.0277832241684 1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component P ABC transporter, ATP-binding protein 249326 1.3157808917938 3.15520243145459 1.06862896074816 600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component P ABC transporter, permease protein 249327 1.23839878356971 2.79080905349601 0.973882064325383 715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components P putative aliphatic sulfonate binding protein precursor 249328 1.33783294703662 3.14071868928074 1.06663812725581 4800 Predicted transcriptional regulator with an HTH domain K Conserved hypothetical protein 249329 1.27295746771199 3.03378309972104 1.08488658488834 - - - hypothetical protein 249330 1.36292177484474 3.15290340252558 1.05983638055979 611 Thiamine monophosphate kinase H thiamin-monophosphate kinase 249331 1.27144680756081 2.91166898774142 1.00026710477233 1180 Pyruvate-formate lyase-activating enzyme O Ribonucleoside-triphosphate reductase activating enzyme 249332 1.27241804248282 2.83122423394953 0.998263589346766 1328 Oxygen-sensitive ribonucleoside-triphosphate reductase F Anaerobic ribonucleoside-triphosphate reductase 249333 1.31980299432815 2.9715653893542 0.973252207054665 695 Glutaredoxin and related proteins O Glutaredoxin-like protein 249334 1.35582186634547 3.14788383479879 1.07914837545438 468 RecA/RadA recombinase L DNA repair protein 249335 1.31015648476201 2.99137079942952 1.04306789306673 1260 Myo-inositol-1-phosphate synthase I Myo-inositol-1-phosphate synthase 249336 1.32214497698325 3.08527698418227 1.07744195538309 182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family J Archaeal protein translation initiation factor 2B subunit 1 249337 1.29559917145017 3.14041539822608 1.10559446726494 - - - hypothetical protein 249338 1.28791256103055 3.08735316205922 1.0366661835821 412 Dienelactone hydrolase and related enzymes Q hydrolase 249339 1.32640915683333 3.0566026795914 1.07498870851357 1193 Mismatch repair ATPase (MutS family) L DNA mismatch repair protein 249340 1.31462978017645 2.97335471286761 1.04651810326412 855 Polyphosphate kinase P Polyphosphate kinase 249341 1.35453867906045 3.08893809451904 1.07600740619759 248 Exopolyphosphatase FP Exopolyphosphatase 249342 1.30309225769694 2.88577800531663 1.0168634645571 5607 Uncharacterized conserved protein S hypothetical protein 249343 1.33173781334124 3.06057859616986 1.0640121229077 1474 Cdc6-related protein, AAA superfamily ATPase LO origin recognition complex subunit 249344 1.2667412080261 2.92965166164126 0.960559624621483 459 Chaperonin GroEL (HSP60 family) O Thermosome, alpha subunit 249345 1.2857218824203 2.96739809785353 1.02759391489213 443 Molecular chaperone O Chaperone protein 249346 1.2965470045952 3.06816266059367 1.04849190257954 484 DnaJ-class molecular chaperone with C-terminal Zn finger domain O Chaperone protein 249347 1.24033629270542 2.82375373613588 0.945406187483937 2043 Uncharacterized protein conserved in archaea S conserved protein 249348 1.28869546911131 2.8599064380899 1.01497714429731 2024 Phenylalanyl-tRNA synthetase alpha subunit (archaeal type) J Phenylalanyl-tRNA synthetase, alpha chain 249349 1.25511089812562 2.80310742487249 0.980295610058613 2178 Predicted RNA-binding protein of the translin family J Superfamily I DNA and RNA helicase 249350 1.38651949434828 3.49467902730272 1.13877858918295 1698 Uncharacterized protein conserved in archaea S conserved protein 249351 1.37029284631957 2.98495007184486 1.00936492923527 1645 Uncharacterized Zn-finger containing protein R hypothetical protein 249352 1.30007189058567 2.96389162655541 1.05707209402123 1111 ERCC4-like helicases L ATP-dependent RNA helicase, EIF-4A family 249353 1.29739406633703 2.87738694783939 1.01287417640268 423 Glycyl-tRNA synthetase (class II) J Glycyl-tRNA synthetase 249354 1.47681444048824 3.551740327352 1.12961070759952 - - - conserved protein 249355 1.33021774476341 3.27438482284577 1.08213190947813 1584 Predicted membrane protein S putative transcriptional regulator 249356 1.28924895947478 3.07696216124152 1.04031933977571 496 Predicted acid phosphatase R Survival protein 249357 1.17707087874534 2.57225375165124 1.03041529746026 - - - hypothetical protein 249358 1.2519203792288 2.83712630196744 0.993017690278572 2896 Molybdenum cofactor biosynthesis enzyme H Molybdenum cofactor biosynthesis protein A 249359 1.3166674255051 3.0552753382149 1.07677117131932 1797 Cobyrinic acid a,c-diamide synthase H Cobyrinic acid a,c-diamide synthase 249360 1.32836580318208 2.89732967964992 0.87058171968587 - - - conserved protein 249361 1.30682055578351 2.88486134052458 1.00303154638695 2219 Eukaryotic-type DNA primase, large subunit L conserved protein 249362 1.3187090773645 3.0915689836432 1.0686931947417 592 DNA polymerase sliding clamp subunit (PCNA homolog) L DNA polymerase sliding clamp 249363 1.2480361540741 2.73827827158279 0.941508528527083 1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS K DNA-directed RNA polymerase subunit M 249364 1.26293716468013 2.92882270580473 1.02991918462265 1051 ADP-ribose pyrophosphatase F MutT-like protein 249365 1.31352300754546 2.84190744900787 0.907794704145896 - - - hypothetical protein 249366 1.31227459516963 3.2074871031365 1.11401660599984 4083 Predicted membrane protein S hypothetical protein 249367 1.25398927806283 2.94601250943484 1.00349847921112 688 Phosphatidylserine decarboxylase I Phosphatidylserine decarboxylase 249368 1.33960925655048 3.26224313873628 1.13879014398576 1183 Phosphatidylserine synthase I CDP-diacylglycerol--serine O-phosphatidyltransferase 249369 1.32593730318585 3.03601729773087 1.0485288849408 2098 Uncharacterized protein conserved in archaea S conserved protein 249370 1.3071512240046 3.06852462072749 1.08532905535302 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E Histidinol-phosphate aminotransferase 249371 1.30013379902604 3.01539264051806 1.06293287646234 4992 Ornithine/acetylornithine aminotransferase E Acetylornithine aminotransferase 249372 1.25247607069365 2.95438893517531 1.01430173075794 4801 Predicted acyltransferase R conserved protein 249373 1.38048411512309 3.25292574071072 1.06130588365581 1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit O archaeosine tRNA-ribosyltransferase 249374 1.33588321247797 3.06840829834706 1.03414880928351 - - - hypothetical protein 249375 1.30403271989738 2.96883433325874 1.02099889730476 - - - hypothetical protein 249376 1.26592475377823 2.85916287942994 1.01475719714959 - - - hypothetical protein 249377 1.27252085133617 2.90780255896734 0.9700008130283 - - - hypothetical protein 249378 1.32200005887257 2.93267848565783 0.979155189635891 4033 Uncharacterized protein conserved in archaea S conserved protein 249379 1.31456300336316 3.01644005152145 1.02082368254992 4081 Uncharacterized protein conserved in archaea S conserved protein 249380 1.30587844421001 2.98864756442992 1.03128920889669 4033 Uncharacterized protein conserved in archaea S conserved protein 249381 1.28695801685242 2.95523340915114 1.00889186733215 150 Phosphoribosylaminoimidazole (AIR) synthetase F Phosphoribosylformylglycinamidine cyclo-ligase 249382 1.28903080833383 3.06331608118663 1.07288718601183 527 Aspartokinases E Aspartate kinase 249383 1.32145591137042 3.05029619263034 1.05671017058321 3635 Predicted phosphoglycerate mutase, AP superfamily G 3-phosphonopyruvate decarboxylase 249384 1.30557492245917 2.79813128999092 0.966272670454769 71 Molecular chaperone (small heat shock protein) O Small heat shock protein 249385 1.31464987436578 2.81650960685932 0.996437026964143 - - - hypothetical protein 249386 1.27481011620332 2.89206662790281 1.01075588532964 1478 Uncharacterized conserved protein S conserved protein 249387 1.31010311618243 3.01318861950688 1.00979835940078 1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain S hypothetical protein 249388 1.30633541952351 3.02328646593917 1.02039172820078 2131 Deoxycytidylate deaminase F dCMP deaminase 249389 1.35585142333264 3.32059576755963 1.09508361970565 341 Preprotein translocase subunit SecF U protein translocase subunit SecF 249390 1.25072467294232 3.00283127298938 1.06781908106045 342 Preprotein translocase subunit SecD U protein translocase subunit SedD 249391 1.33658167241109 3.10523000030946 1.05203787085961 470 ATPase involved in DNA replication L replication factor C subunit 249392 1.34788129413331 3.19272342826197 0.983637793176144 - - - conserved protein 249393 1.29613343918767 2.90125957404582 0.929465445736832 - - - conserved protein 249394 1.32146779019509 2.83966389807407 0.896266333272815 - - - Transposase 249395 1.32641137149076 2.94349259941172 0.897713274882092 3547 Transposase and inactivated derivatives L Transposase 249396 1.3872706977279 3.22424642034232 0.971758594547916 3547 Transposase and inactivated derivatives L Transposase 249397 1.41869903884781 3.34101336478691 1.10013184895478 - - - hypothetical protein 249398 1.29024501482402 3.09584014145453 1.12382194606502 841 Cation/multidrug efflux pump V hypothetical protein 249399 1.40928151183394 3.30319888182341 1.06606473786912 - - - Monomethylamine permease 249400 1.29920761988792 3.12770343623172 1.09135761288714 833 Amino acid transporters E Monomethylamine permease 249401 1.20420862255583 2.82042322332682 0.871466835222818 - - - Monomethylamine:corrinoid methyltransferase 249402 1.2900786711364 2.86013855423931 0.927065232827782 - - - Monomethylamine:corrinoid methyltransferase 249403 1.30931389410015 3.01525503884411 1.00713190858477 5012 Predicted cobalamin binding protein R Monomethylamine corrinoid protein 249404 1.25028574842495 2.84447474361865 1.00007539898997 407 Uroporphyrinogen-III decarboxylase H Methylcobalamin:coenzyme M methyltransferase 249405 1.26893788744186 2.8957112442669 1.02341105984733 3894 Uncharacterized metal-binding protein R conserved protein 249406 1.35687687529271 2.93895124596886 0.962424277744052 221 Inorganic pyrophosphatase C Inorganic pyrophosphatase 249407 1.27558897530232 3.00081362916915 1.0572054949583 - - - hypothetical protein 249408 1.3186539302932 2.98999572356973 1.0087394527778 458 Carbamoylphosphate synthase large subunit (split gene in MJ) EF hypothetical protein 249409 1.26755530760432 2.82985018876237 1.00842071570807 502 Biotin synthase and related enzymes H biotin synthetase 249410 1.29692091089411 3.03326348549753 1.0469560547188 17 Aspartyl/asparaginyl-tRNA synthetases J hypothetical protein 249411 1.35683495659951 3.16073564502431 1.11651651783998 - - - hypothetical protein 249412 1.28499504679444 2.98458828267147 1.03627613893381 - - - hypothetical protein 249413 1.39737213580511 3.14399372541307 1.03291021707774 1342 Predicted DNA-binding proteins R hypothetical protein 249414 1.42320387158103 3.30231871005311 1.05108742346097 - - - conserved protein 249415 1.26742810394813 2.90440663879949 1.02913570974682 731 Fe-S oxidoreductases C Fe-S oxidoreductase 249416 1.29648317314187 2.98767486499032 1.00164407320984 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 249417 1.36710995004829 3.03592558718853 1.0228685980446 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 249418 1.37433277869814 3.06263804032154 0.999185072800961 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 249419 1.33272357471978 3.05346076601193 1.02177339173208 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 249420 1.27191111340124 2.92682929086752 1.01742498173168 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 249421 1.28094964149574 2.95097373532003 1.01696395014456 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 249422 1.27349375775722 2.91942784265488 1.00192966752835 3482 Uncharacterized conserved protein S conserved protein 249423 1.29392208860778 3.0204963383373 1.04919492141585 1944 Uncharacterized conserved protein S conserved protein 249424 1.40535773081946 3.37410530116302 1.1214519175692 - - - hypothetical protein 249425 1.31355972430163 2.78709979996753 0.977791968686822 - - - conserved protein 249426 1.48224011731626 3.52392544666371 1.17210904452314 474 Cation transport ATPase P Cation-transporting ATPase 249427 1.31912150347132 2.9764159365814 0.938927590797828 - - - hypothetical protein 249428 1.31192024120663 3.07494254270374 1.07068045683917 2217 Cation transport ATPase P Copper-exporting ATPase 249429 1.25366272315706 3.01079977237319 0.999513661618876 - - - hypothetical protein 249430 1.31053025602937 3.16429297225169 1.09517793352769 2270 Permeases of the major facilitator superfamily R hypothetical membrane spanning protein 249431 1.40036336358936 2.99815967294974 0.949653234506775 - - - hypothetical protein 249432 1.37317657290745 3.03664242168756 0.909457366163471 - - - hypothetical protein 249433 1.36646949591424 3.2388996692968 1.04854008686468 - - - hypothetical protein 249434 1.49956194009921 3.4480116866775 1.08343182187889 3315 O-Methyltransferase involved in polyketide biosynthesis Q conserved protein 249435 1.28417346929242 2.89251177353107 0.994330563764826 16 Phenylalanyl-tRNA synthetase alpha subunit J Phenylalanyl-tRNA synthetase, alpha chain 249436 1.27903741128389 2.81900021434068 1.00054945744412 180 Tryptophanyl-tRNA synthetase J Tryptophanyl-tRNA synthetase 249437 1.35259054894154 3.11398682244786 1.02634644881856 - - - putative nucleotidyltransferase 249438 1.42057389597763 3.17596928166689 1.03042870414867 2445 Uncharacterized conserved protein S conserved protein 249439 1.30463526149816 2.97367080009183 1.04013067988894 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 249440 1.2802584413657 2.93092343278097 1.05073864972293 1601 Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain J putative translation initiation factor 2 beta subunit 249441 1.30362417513812 2.96897738500773 0.963498620142462 197 Ribosomal protein L16/L10E J LSU ribosomal protein L10AE 249442 1.32113242042386 3.03760317833803 1.01293972959781 4012 Uncharacterized protein conserved in archaea S Pyruvate formate-lyase activating enzyme 249443 1.25152484357787 2.97409444244703 0.996524568294571 521 Molybdopterin biosynthesis enzymes H Molybdenum cofactor biosynthesis protein B 249444 1.33543125131083 2.99899422422864 1.05540541791527 553 Superfamily II DNA/RNA helicases, SNF2 family KL SWF/SNF family helicase 249445 1.32296975455941 3.02316800070977 1.05251983357701 4279 Uncharacterized conserved protein S conserved protein 249446 1.33974847461594 3.17690251603191 1.08179015680842 - - - Iron-dependent repressor 249447 1.38115749389989 3.25915110391832 1.10305443418944 370 Fe2+ transport system protein B P hypothetical protein 249448 1.33183058322695 3.3804824734899 1.10959176156185 - - - Ferrous iron transport protein B 249449 1.2539008174564 2.76589004398438 0.99282022958778 4742 Predicted transcriptional regulator K conserved protein 249450 1.23268955223533 2.79367535681162 1.02150779140681 1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein J conserved protein 249451 1.29480479573102 2.93738089136124 1.0408185395871 13 Alanyl-tRNA synthetase J Alanyl-tRNA synthetase 249452 1.36651576087492 2.98345491120557 1.00535539781325 2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase J methyltransferase 249453 1.37645755003208 3.04213792225425 0.996541095303134 456 Acetyltransferases R hypothetical protein 249454 1.27772671401792 2.89908323976465 0.991711081257519 473 Isocitrate/isopropylmalate dehydrogenase CE 3-isopropylmalate dehydrogenase 249455 1.29586367472326 2.98462983609397 1.00319770076749 66 3-isopropylmalate dehydratase small subunit E 3-isopropylmalate dehydratase 249456 1.32255911691749 3.09521864680907 1.08724446114914 433 Predicted ATPase R putative nucleotidyltransferase 249457 1.36496574768894 3.09763280557395 1.02205159933981 4742 Predicted transcriptional regulator K conserved protein 249458 1.28088849244448 2.93117722039632 1.01973865653134 1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) R conserved protein 249459 1.27877944660304 2.99775009264043 1.04914503931725 - - - hypothetical transcriptional regulatory protein 249460 1.29554880059125 3.02914892585206 1.03189280786897 101 Pseudouridylate synthase J tRNA pseudouridine synthase A 249461 1.29205956137881 2.93871255298221 1.01234013718484 1041 Predicted DNA modification methylase L putative methyltransferase 249462 1.33033247416853 2.92550754517385 1.02404224935302 3377 Uncharacterized conserved protein S conserved protein 249463 1.33570307832666 3.0406318983169 1.04468714632658 - - - hypothetical protein 249464 1.23802148593599 2.87624347424971 1.01519626004289 24 Methionine aminopeptidase J Methionine aminopeptidase 249465 1.29317795369713 2.91731513106801 1.03417967695855 6 Xaa-Pro aminopeptidase E Xaa-Pro aminopeptidase 249466 1.3932417907477 3.05467171786459 1.04743436883383 - - - hypothetical protein 249467 1.31044574301724 3.05715794555858 1.03158911067784 1812 Archaeal S-adenosylmethionine synthetase E S-adenosylmethionine synthetase 249468 1.27054153526849 2.99906314713212 1.04921719924199 40 ATP phosphoribosyltransferase E ATP phosphoribosyltransferase 249469 1.26213660495374 3.04094554211457 1.04673215801286 106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase E Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 249470 1.31974797603154 2.98674131107167 1.03030413914993 131 Imidazoleglycerol-phosphate dehydratase E Imidazoleglycerol-phosphate dehydratase 249471 1.33428499786472 3.04508761103689 1.0264942657425 1526 Uncharacterized protein required for formate dehydrogenase activity C FdhD protein 249472 1.27830559596101 3.03154748503704 1.05539124240867 - - - hypothetical protein 249473 1.34202007527652 3.29484463552454 1.13178535024608 - - - hypothetical protein 249474 1.33866243804849 3.10250644642773 1.01018895234035 - - - hypothetical protein 249475 1.27230859843301 2.99244762387181 1.07737136875876 - - - hypothetical protein 249476 1.2563216387488 3.05613820098433 1.04191003581974 3430 Uncharacterized protein conserved in archaea S hypothetical protein 249477 1.29631075202429 3.04553196718543 1.02659162685555 - - - hypothetical protein 249478 1.31875064101263 3.08187898592808 1.02313289264474 - - - hypothetical protein 249479 1.35318762167859 3.1242055263042 1.04922774839589 - - - hypothetical protein 249480 1.29186838298872 3.08328068267236 1.08463189477395 2064 Flp pilus assembly protein TadC NU Transporter 249481 1.29410154851538 2.97824166312061 1.05891919858604 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU Type II secretion system protein 249482 1.31153031328801 3.07222488900693 1.05143228108714 520 Selenocysteine lyase E Cysteine desulfurase 249483 1.33116963944748 3.02886586337032 1.02893160404237 1772 Uncharacterized protein conserved in archaea S conserved protein 249484 1.3046718086404 2.90756684749848 0.960420548877607 1246 N-acetylglutamate synthase and related acetyltransferases E Amino-acid acetyltransferase 249485 1.27789229541851 2.85755929291797 0.973739313655447 1606 ATP-utilizing enzymes of the PP-loop superfamily R conserved protein 249486 1.32511698585466 3.12864748317987 1.10895548531385 1109 Phosphomannomutase G phosphoglucomutase 249487 1.33535465704775 3.08273010073788 1.07184485383497 1032 Fe-S oxidoreductase C Fe-S oxidoreductase 249488 1.32506501521645 3.14806251352017 1.0914220705946 750 Predicted membrane-associated Zn-dependent proteases 1 M Zinc metalloprotease 249489 1.25142325926454 2.92503947004152 1.03167557806689 1786 Uncharacterized conserved protein S conserved protein 249490 1.28315048325227 2.94567996354307 1.03058915613242 1679 Uncharacterized conserved protein S conserved protein 249491 1.28185712516802 2.99515145348984 1.03473045434681 43 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases H 4-hydroxybenzoate decarboxylase 249492 1.29278473837906 2.95625409140161 1.0041924028901 372 Citrate synthase C Citrate synthase 249493 1.29789412441997 3.02567997225668 1.07650653659736 1048 Aconitase A C Aconitate hydratase 249494 1.29900206656329 3.07109484498255 1.07288444579801 - - - hypothetical protein 249495 1.30614697210133 2.87650055448486 1.01366982700281 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R hypothetical protein 249496 1.30591527362896 2.91373445815641 1.04047039172089 714 MoxR-like ATPases R putative regulatory protein 249497 1.4212134581239 3.4830526972093 1.14407670001661 - - - hypothetical protein 249498 1.28551917053784 2.9744935502863 0.996907668267634 476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 H Molybdopterin biosynthesis MoeB protein 249499 1.29872232417668 2.91251073304084 1.02417955932163 - - - hypothetical protein 249500 1.3004247124349 3.19783367752328 1.10608465321995 235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases G L-fuculose phosphate aldolase 249501 1.26992428975862 3.14709348530537 1.09640492193878 558 Phosphatidylglycerophosphate synthase I CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 249502 1.2832090841649 2.79890872011509 0.992396011079028 1371 Uncharacterized conserved protein S conserved protein 249503 1.28804305441149 2.97374868905623 1.05660825103986 1690 Uncharacterized conserved protein S Replication factor C subunit 249504 1.25674152617717 2.8072635733102 0.964175800967843 - - - hypothetical protein 249505 1.2677435942655 2.93996051816599 0.983987585773088 1962 Tetrahydromethanopterin S-methyltransferase, subunit H H Tetrahydromethanopterin S-methyltransferase, subunit H 249506 1.29370013978346 2.92803750433741 1.00330955727828 4064 Tetrahydromethanopterin S-methyltransferase, subunit G H Tetrahydromethanopterin S-methyltransferase, subunit G 249507 1.40286487336087 3.33746079669843 1.11522551833211 4218 Tetrahydromethanopterin S-methyltransferase, subunit F H Tetrahydromethanopterin S-methyltransferase, subunit F 249508 1.32124352957059 3.12823106549149 1.05176888489466 4063 Tetrahydromethanopterin S-methyltransferase, subunit A H Tetrahydromethanopterin S-methyltransferase, subunit A 249509 1.33924658738875 3.34400964187538 1.07963098991766 4062 Tetrahydromethanopterin S-methyltransferase, subunit B H Tetrahydromethanopterin S-methyltransferase, subunit B 249510 1.33981443991186 3.31748308932901 1.09802955420539 4061 Tetrahydromethanopterin S-methyltransferase, subunit C H Tetrahydromethanopterin S-methyltransferase, subunit C 249511 1.26794614853876 3.26517619849341 1.09438499008966 4060 Tetrahydromethanopterin S-methyltransferase, subunit D H Tetrahydromethanopterin S-methyltransferase, subunit D 249512 1.36647391091488 3.34559590209242 1.11609779362408 4059 Tetrahydromethanopterin S-methyltransferase, subunit E H Tetrahydromethanopterin S-methyltransferase, subunit E 249513 1.23995497788761 2.8752542887449 1.00997111505768 1082 Sugar phosphate isomerases/epimerases G conserved protein 249514 1.27919752085396 3.13350949556379 1.09134275472829 591 Na+/proline symporter ER sodium/proline symporter 249515 1.3181351735272 3.02499732687147 1.01690713762816 2005 N-terminal domain of molybdenum-binding protein R putative molybdenum transport protein ModA 249516 1.2532412773095 2.79889763131488 0.992827767076545 1361 S-layer domain M hypothetical protein 249517 1.30481132829435 2.99329389938532 1.03219916549063 1361 S-layer domain M hypothetical protein 249518 1.30261236237881 3.08188981823927 1.08653423770014 1033 Predicted exporters of the RND superfamily R transporter, RND superfamily 249519 1.32332894605788 2.9003058627341 1.01883884446366 1378 Predicted transcriptional regulators K transcriptional regulator 249520 1.26371149529145 2.88444948875479 0.938296459921958 2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold R putative metal dependent hydrolase 249521 1.31866377047766 2.87302200420307 1.01547580827345 2023 RNase P subunit RPR2 J conserved protein 249522 1.22883170628694 2.77671391590531 0.981914519482428 1400 Signal recognition particle 19 kDa protein U Signal recognition particle SEC65 subunit 249523 1.23786715094356 3.08218220486086 1.0879833186497 - - - hypothetical protein 249524 1.26326986080522 2.89768881037348 0.98478618178372 - - - hypothetical protein 249525 1.25506314339026 3.05241349030261 1.0398875349115 - - - hypothetical protein 249526 1.29825492289225 3.01604746244145 1.00190354663225 2998 ABC-type tungstate transport system, permease component H ABC transporter tungsten-binding protein 249527 1.38433949214596 3.45177977393687 1.1383491736838 4662 ABC-type tungstate transport system, periplasmic component H tungsten transporter, permease protein 249528 1.29877113468321 3.00619049154913 1.03157497883543 3839 ABC-type sugar transport systems, ATPase components G tungsten transporter, ATP binding protein 249529 1.32844004658108 2.90876346277214 0.992218340686168 2191 Formylmethanofuran dehydrogenase subunit E C molybdenum-containing formylmethanofuran dehydrogenase isoenzyme I subunit E 249530 1.30127861850685 2.89862954619801 1.00031843663499 1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) C molybdenum formylmethanofuran dehydrogenase subunit 249531 1.28612544675019 2.97185960221013 1.01725271201267 1229 Formylmethanofuran dehydrogenase subunit A C molybdenum formylmethanofuran dehydrogenase subunit 249532 1.29632195119593 3.04419327862258 1.05887344153814 2218 Formylmethanofuran dehydrogenase subunit C C molybdenum formylmethanofuran dehydrogenase subunit 249533 1.32877582867524 3.19044079609811 1.0865550777076 1153 Formylmethanofuran dehydrogenase subunit D C molybdenum-containing formylmethanofuran dehydrogenase 249534 1.3391374085223 3.09607301221811 1.05552446226199 1029 Formylmethanofuran dehydrogenase subunit B C molybdenum formylmethanofuran dehydrogenase subunit 249535 1.45054661098244 3.17023934623811 0.995592004180473 4892 Predicted heme/steroid binding protein R conserved protein 249536 1.29663381633161 3.1084281828573 1.06760442718195 2968 Uncharacterized conserved protein S conserved protein 249537 1.28747900570345 2.93971449509477 1.00754017337973 - - - conserved protein 249538 1.41281432877579 3.03818582669147 0.904468153479259 - - - Transposase 249539 1.27440851725192 2.87777630815356 0.905896956524026 2230 Cyclopropane fatty acid synthase and related methyltransferases M conserved protein 249540 1.37909783583125 3.18786484058996 1.01172242915154 - - - conserved protein 249541 1.38045160540337 3.21419652399114 1.07288818201961 2014 Uncharacterized conserved protein S conserved protein 249542 1.29157044623752 2.91499174798024 1.01122469984056 157 Nicotinate-nucleotide pyrophosphorylase H Nicotinate-nucleotide pyrophosphorylase 249543 1.31358604463848 3.04248742057931 1.04705108047354 3839 ABC-type sugar transport systems, ATPase components G Molybdate ABC transporter, ATP-binding protein 249544 1.32645383707118 3.31356158424442 1.09437127300104 555 ABC-type sulfate transport system, permease component O Molybdate ABC transporter, permease protein 249545 1.27068459558516 2.90766724897771 1.01003028764959 725 ABC-type molybdate transport system, periplasmic component P Molybdate-binding protein 249546 1.2868592442026 2.86787336276469 0.985178647840327 2249 Putative NADPH-quinone reductase (modulator of drug activity B) R putative NAD(P)H oxidoreductase[quinone] 249547 1.28303131961092 2.92570214998076 1.02952302317247 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 249548 1.36775851978047 2.84443175055679 0.949034469683855 1359 Uncharacterized conserved protein S conserved protein 249549 1.30632086867773 2.98992049774863 1.03925320404796 778 Nitroreductase C NADPH-flavin oxidoreductase 249550 1.26559593543995 2.79414231280046 0.953490212754731 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 249551 1.37274840703418 3.04684667044853 1.01795834542261 1733 Predicted transcriptional regulators K transcriptional regulator, MarR family 249552 1.31072276975899 2.9912033339269 1.06226411254589 1199 Rad3-related DNA helicases KL DNA repair helicase 249553 1.30756914836331 3.36111649090034 1.12088840396077 3291 FOG: PKD repeat R surface layer protein B 249554 1.28895827051092 3.12890356389809 1.10696121552638 3291 FOG: PKD repeat R surface layer protein B 249555 1.27440878285889 2.89824675298043 1.01162829447004 3874 Uncharacterized conserved protein S conserved protein 249556 1.34593364556272 3.00786926388994 1.04369954880864 - - - conserved protein 249557 1.32003837979017 3.17753377534323 1.08967627881141 1907 Predicted archaeal sugar kinases R conserved protein 249558 1.31280119084439 3.05666972942166 1.05724476904254 1498 Protein implicated in ribosomal biogenesis, Nop56p homolog J putative RNA processing protein 249559 1.27582822718579 2.9209041084629 1.02046892435222 1889 Fibrillarin-like rRNA methylase J Fibrillarin 249560 1.30771774793955 3.02411425118222 0.998677299450715 - - - conserved protein 249561 1.33449912741334 3.37519809958312 1.1578878731086 4827 Predicted transporter R conserved protein 249562 1.30766513338631 3.03132641521663 1.05093891873039 811 Biopolymer transport proteins U integral membrane protein 249563 1.39225504496286 3.41226625960224 1.11882410885804 4744 Uncharacterized conserved protein S conserved protein 249564 1.35652021443411 3.31575082071244 1.08266464595434 428 Predicted divalent heavy-metal cations transporter P integral membrane protein 249565 1.29907446802675 2.82584651963156 0.872323989915762 - - - hypothetical protein 249566 1.25797579137219 2.9406757959512 1.05467011799339 1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases H Cobalamin biosynthesis protein 249567 1.29832365015691 3.02411614302762 1.06403289175563 1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases H Cobalamin biosynthesis protein CobN 249568 1.35281444946073 2.99029026948019 1.01710271366536 1720 Uncharacterized conserved protein S conserved protein 249569 1.27037453548962 2.78275386452036 0.946953909358267 2191 Formylmethanofuran dehydrogenase subunit E C tungsten formylmethanofuran dehydrogenase, subunit E 249570 1.29563032685178 2.99566120827938 0.994499951149456 4742 Predicted transcriptional regulator K conserved protein 249571 1.2757087302789 3.00762952282416 1.05932841730891 1184 Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family J Archaeal protein translation initiation factor 2B subunit 2 249572 1.29543813992488 2.8268793630085 0.772844177053918 456 Acetyltransferases R Acetyltransferase 249573 1.29252900370057 2.95854481323011 1.01924384076598 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 249574 1.33870175932295 3.28464165720092 1.14642863151646 4591 ABC-type transport system, involved in lipoprotein release, permease component M ABC transporter, permease protein 249575 1.28591707269245 2.98767004600492 1.03783947272715 - - - hypothetical binding protein of ABC transporter 249576 1.23150414816379 2.94955941669644 0.985377781827666 528 Uridylate kinase F Uridylate kinase 249577 1.3034637819828 3.04429607583736 1.0763726034437 - - - conserved protein 249578 1.34867328395046 3.00803570885353 1.04558264034678 1641 Uncharacterized conserved protein S conserved protein 249579 1.29047742167655 2.9134806796721 1.0090742093211 1309 Transcriptional regulator K transcriptional regulator, TetR family 249580 1.3198556648587 2.90966852709367 1.008730653076 1453 Predicted oxidoreductases of the aldo/keto reductase family R oxidoreductase, ALDO/KETO reductase family 249581 1.36352196228505 3.26011551621232 1.1363125874699 1691 NCAIR mutase (PurE)-related proteins R Phosphoribosylaminoimidazole carboxylase 249582 1.30616911928021 3.04688132156491 1.05075046894696 1641 Uncharacterized conserved protein S conserved protein 249583 1.29434661623693 3.04679066759092 1.06654763468788 136 Aspartate-semialdehyde dehydrogenase E Aspartate-semialdehyde dehydrogenase 249584 1.17806143353807 2.49866604197667 0.915372270907451 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C Ferredoxin 249585 1.2818645997711 2.79432790521244 0.973863310803096 - - - conserved protein 249586 1.31348242595601 3.02249931094458 1.06805470814088 523 Putative GTPases (G3E family) R divalent cation transport protein 249587 1.25402674055519 2.63018663341795 0.937817027586646 - - - conserved protein 249588 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 249589 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 249590 1.15207171678254 2.60039544584106 0.903030748393133 - - - conserved protein 249591 1.30577458904258 3.07534915682887 1.04115192748571 2516 Biotin synthase-related enzyme R conserved protein 249592 1.27848679614023 3.01321642044886 1.03531404443098 1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes G Fructose-bisphosphate aldolase 249593 1.24791944809653 2.83446950894529 0.989708116892106 717 Deoxycytidine deaminase F Deoxycytidine triphosphate deaminase 249594 1.28140282225695 3.03219290746357 1.0608394156245 5306 Uncharacterized conserved protein S conserved protein 249595 1.37539171399977 3.32164317250109 1.11327592476079 - - - conserved protein 249596 1.31244087419516 3.05442968894009 1.05652709415363 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 249597 1.33089438503559 2.98513102748851 1.01867859616885 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 249598 1.27183726747452 3.06956943655785 1.08511538476724 4591 ABC-type transport system, involved in lipoprotein release, permease component M ABC transporter, ATP-binding protein 249599 1.30445827944255 2.90951690257051 0.990393267169686 229 Conserved domain frequently associated with peptide methionine sulfoxide reductase O transcriptional regulator 249600 1.33265647457201 2.94606764563445 1.01404424211292 637 Predicted phosphatase/phosphohexomutase R Beta-phosphoglucomutase 249601 1.29113792853461 2.97788986284315 1.04422075413577 1819 Glycosyl transferases, related to UDP-glucuronosyltransferase GC glycosyltransferase 249602 1.42621408915634 3.49263530230702 1.12305050315428 - - - conserved protein 249603 1.42823166883023 3.33851834899293 1.02679766993331 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase 249604 1.34505587196735 3.20817211349707 1.02106155846242 110 Acetyltransferase (isoleucine patch superfamily) R putative acetyltransferase 249605 1.31163157970362 3.05854576306345 0.946434915265085 726 Predicted xylanase/chitin deacetylase G putative polysaccharide deacetylase 249606 1.42476001033884 3.31728401676977 0.99154987398422 438 Glycosyltransferase M glycosyltransferase 249607 1.3849002441532 3.33453735459049 0.999933675098806 4906 Predicted membrane protein S Conserved transmembrane protein 249608 1.40187076823816 3.47614726904838 1.08557314144186 - - - oligosaccharide repeat unit transporter 249609 1.32951561445368 2.99157672910479 0.908294691035998 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H methyltransferase 249610 1.31050002630922 3.11108495676303 0.936932353565576 - - - hypothetical protein 249611 1.36112450218511 3.44110006844139 1.14205493969744 - - - conserved protein 249612 1.24800530625001 2.8276357181873 0.739349238503435 - - - Methanol:corrinoid methyltransferase MtaB 249613 1.2832719508399 2.89678808749107 0.953478175651399 5012 Predicted cobalamin binding protein R Methanol corrinoid protein MtaC 249614 1.23436062545196 2.80310285663027 0.988344583669388 4742 Predicted transcriptional regulator K conserved protein 249615 1.32402822949539 3.03540718119896 1.01971859334798 4742 Predicted transcriptional regulator K conserved protein 249616 1.32144652055088 2.99797992678263 1.01724251347324 3663 G:T/U mismatch-specific DNA glycosylase L conserved protein 249617 1.22135635280468 2.57831146939662 0.966580244126157 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C Ferredoxin 249618 1.33301246107355 3.00993536678734 0.959295027880421 - - - conserved protein 249619 1.34027736366883 3.09451649522684 1.06598303036439 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyltransferase 249620 1.30896532765498 2.84816125973455 1.00240235719873 4715 Uncharacterized conserved protein S conserved protein 249621 1.31365562704075 3.01609417710089 1.05861247015164 665 Glycine/D-amino acid oxidases (deaminating) E oxidoreductase 249622 1.26692791488989 2.89645756430885 1.01976696694619 4639 Predicted kinase R putative serine/threonine protein phosphatase 249623 1.29085102525827 2.98210864538169 1.04846098054047 840 Methyl-accepting chemotaxis protein NT methyl-accepting chemotaxis protein 249624 1.38075177229662 3.45124548521969 1.07640485773475 - - - hypothetical protein 249625 1.3839934715375 3.26676577340089 1.11804084535594 2239 Mg/Co/Ni transporter MgtE (contains CBS domain) P MG2+ transporter MGTE 249626 1.33739108471412 2.95406641549334 1.0179594955555 4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V type I restriction-modification system restriction subunit 249627 1.39353955290566 3.08644692781672 1.02280829469171 - - - transcriptional regulatory protein, AsnC family 249628 1.31319067894682 2.91368666857255 0.975171963309461 - - - conserved protein 249629 1.39093259066662 3.03532017686639 0.975121795786542 2405 Predicted nucleic acid-binding protein, contains PIN domain R conserved protein 249630 1.34757496614196 3.10131477758342 0.993483397687449 - - - conserved protein 249631 1.41352419721244 3.06001896738341 0.90078515258637 - - - ATPase involved in DNA repair 249632 1.41201599202893 3.05432760741237 0.968857081968973 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 249633 1.37224052008347 3.04237126921041 1.00939024808771 2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared wi K ATP-dependent DNA helicase RecG 249634 1.29910804153282 2.88212864938967 0.948581691983812 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system specificity subunit 249635 1.28031857841226 3.0703267659611 1.05537443041582 - - - conserved protein 249636 1.29918385148946 2.92061762214451 1.04046087291068 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 249637 1.35452249482918 3.11471628677182 1.05140721047008 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H methyltransferase 249638 1.27164246444243 2.86904753333911 0.971405066331568 110 Acetyltransferase (isoleucine patch superfamily) R galactoside-O-acetyltransferase 249639 1.28781664533513 3.08742806159691 1.05783183028471 - - - hypothetical protein 249640 1.41708767879246 3.18930150753832 1.03608278351869 325 Predicted enzyme with a TIM-barrel fold R conserved protein 249641 1.32711180438812 3.19160855799407 1.0389187233741 2333 Predicted hydrolase (metallo-beta-lactamase superfamily) R conserved protein 249642 1.3102521667756 3.12394850226479 1.03546523480935 3391 Uncharacterized conserved protein S conserved protein 249643 1.28140240941836 3.04538327490557 1.05231315030662 1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases NOU conserved protein 249644 1.35117523854173 3.06505477904006 0.928487663413068 3547 Transposase and inactivated derivatives L Transposase 249645 1.2807326826651 2.92676785412939 1.00738838049436 2241 Precorrin-6B methylase 1 H Precorrin-6Y C5,15-methyltransferase [decarboxylating] 249646 1.29187290524548 3.09892373381932 1.07675393072135 1903 Cobalamin biosynthesis protein CbiD H CbiD protein 249647 1.33984028293301 3.03221848666889 1.06409224658442 323 DNA mismatch repair enzyme (predicted ATPase) L DNA mismatch repair protein 249648 1.27732890149639 2.92386038096423 1.02929814562345 249 Mismatch repair ATPase (MutS family) L DNA mismatch repair protein 249649 1.31822088135984 3.10351958927459 1.06542352642232 3594 Fucose 4-O-acetylase and related acetyltransferases G O-acetyl transferase 249650 1.33458815918414 3.32522612956664 1.14798413372701 558 Phosphatidylglycerophosphate synthase I CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 249651 1.29108956473001 2.91505123961836 0.996364954276334 247 Fe-S oxidoreductase C Iron-sulfur binding reductase 249652 1.27227396885456 2.9557944784094 1.0420915715369 5012 Predicted cobalamin binding protein R dimethylamine corrinoid protein 249653 1.23698185311582 2.85073343550302 0.95122776401405 5598 Trimethylamine:corrinoid methyltransferase H Trimethylamine:corrinoid methyltransferase 249654 1.22436979559837 2.77196521138421 0.952471025521783 5598 Trimethylamine:corrinoid methyltransferase H Trimethylamine:corrinoid methyltransferase MttB 249655 1.24203826375204 2.78287665686033 0.943308249710644 5012 Predicted cobalamin binding protein R dimethylamine corrinoid protein 249656 1.34078951021789 3.23057279634297 1.08527748475718 - - - Trimethylamine Permease 249657 1.24086227202662 2.7250544473287 0.904409899306436 - - - conserved protein 249658 1.27563616722994 2.92468596245921 0.959606113941918 - - - dimethylamine:corrinoid methyltransferase 249659 1.37133148304785 3.08723296560482 1.04850357183949 - - - dimethylamine:corrinoid methyltransferase MtbB 249660 1.26011421045588 2.92967282261173 0.987498973069736 3212 Predicted membrane protein S conserved protein 249661 1.30585864335268 2.98385154159663 1.05553210880468 1384 Lysyl-tRNA synthetase (class I) J Lysyl-tRNA synthetase 249662 1.31803199212606 2.98163560398728 1.03128376298231 2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase H conserved protein 249663 1.39945712551674 3.54172350881602 1.15554093754804 - - - conserved protein 249664 1.34557290932101 3.11081230609481 1.05470906944056 - - - conserved protein 249665 1.31827261038366 3.04746187366046 1.08060190461807 826 Collagenase and related proteases O protease 249666 1.30461073656135 3.04083734154036 0.997491974547541 702 Predicted nucleoside-diphosphate-sugar epimerases MG putative nucleoside-diphosphate-sugar epimerase 249667 1.32803955929249 2.83358347195711 0.975190567460596 - - - conserved protein 249668 1.23613815661407 2.63009528249476 0.940147079329889 1694 Predicted pyrophosphatase R conserved protein 249669 1.27349835324919 2.93466941242607 1.02633163961219 107 Imidazoleglycerol-phosphate synthase E Histidine biosynthesis protein 249670 1.32084418223304 3.05706879830134 0.979462407281699 1259 Uncharacterized conserved protein S conserved protein 249671 1.33903859609377 3.0123808763742 1.03487266263531 2518 Protein-L-isoaspartate carboxylmethyltransferase O Protein-L-isoaspartate O-methyltransferase 249672 1.27757292631206 2.89819936513952 1.00027539037165 1326 Uncharacterized archaeal Zn-finger protein R conserved protein 249673 1.28217483012375 3.02852367217776 1.0303875453528 1326 Uncharacterized archaeal Zn-finger protein R conserved protein 249674 1.37131934900134 3.10201623131154 1.07211685627732 1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon KH conserved protein 249675 1.29378117476347 2.99356232086344 1.01866345891668 108 3,4-dihydroxy-2-butanone 4-phosphate synthase H 3,4 dihydroxy-2-butanone 4-phosphate synthase 249676 1.29487958653602 3.1322772761328 1.07913221078489 53 Predicted Co/Zn/Cd cation transporters P Cobalt-zinc-cadmium resistance protein 249677 1.36280982138526 3.3114144087647 1.11173691243984 82 Chorismate synthase E Chorismate synthase 249678 1.32442652314106 2.94878382218182 1.02218627096056 - - - conserved protein 249679 1.33303472375453 3.24675297279734 1.03270292313151 - - - conserved protein 249680 1.34990904759324 3.1874872292492 1.02785937877776 - - - conserved protein 249681 1.32157951022197 2.94752942785859 1.00456520665519 4742 Predicted transcriptional regulator K transcriptional regulator, ArsR family 249682 1.29843428555645 2.95926314778263 0.990513079198569 2834 Outer membrane lipoprotein-sorting protein M conserved protein 249683 1.32343301666578 3.16963292795169 0.969389082785069 - - - conserved protein 249684 1.34461991226534 3.17394340233717 0.984630327449271 - - - hypothetical protein 249685 1.29475629771036 2.95792255791095 1.00341761576928 - - - conserved protein 249686 1.3512003846457 3.04244353721706 1.03752312227373 4742 Predicted transcriptional regulator K transcriptional regulator, ArsR family 249687 1.34284816769825 3.20196253213895 0.979685688448457 - - - hypothetical protein 249688 1.39913727123851 3.18151953632483 0.915445213102357 - - - conserved protein 249689 1.45623871764111 3.39848279689883 1.00514464206866 - - - hypothetical protein 249690 1.4297219415611 3.41977586788618 1.01008941403124 - - - conserved protein 249691 1.33689045366229 3.0064831523295 0.995557771259986 535 Predicted Fe-S oxidoreductases R Heme biosynthesis protein 249692 1.33296419825023 3.0033559593688 0.991518118751629 1522 Transcriptional regulators K Heme biosynthesis protein 249693 1.31009029935701 2.88314372628507 0.986625330792854 1522 Transcriptional regulators K Heme biosynthesis protein 249694 1.23778201470314 2.70963370367001 0.867955193210374 1943 Transposase and inactivated derivatives L Transposase 249695 1.36008052136963 3.06447965987661 0.953740785045788 675 Transposase and inactivated derivatives L Transposase 249696 1.35826813806158 3.16665821863543 1.01823102725188 - - - conserved protein 249697 1.33335019935905 3.01825501739649 1.03170374378079 4742 Predicted transcriptional regulator K transcriptional regulator, ArsR family 249698 1.42395114959246 3.57375686351925 1.10765680728525 - - - metalloproteinase 249699 1.43277633794144 3.40801886889586 1.03494327196035 - - - conserved protein 249700 1.46955864706738 3.3582170655687 0.950318718898591 - - - Transposase 249701 1.33173959750315 2.8276952970768 0.902183132193412 3436 Transposase and inactivated derivatives L Transposase 249702 1.32637517117833 3.00221677312132 1.03536411351492 535 Predicted Fe-S oxidoreductases R Heme biosynthesis protein 249703 1.45055856007376 3.37778763946761 1.10109398072835 1522 Transcriptional regulators K Heme biosynthesis protein 249704 1.28549682073922 2.82902033218069 0.983249536316954 1522 Transcriptional regulators K Heme biosynthesis protein 249705 1.3492313539187 3.19940013494296 1.05244571757717 1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) H Siroheme synthase 249706 1.30296327536554 2.91948466930475 1.02485817909115 373 Glutamyl-tRNA reductase H Glutamyl-tRNA reductase 249707 1.27878919186009 2.9932811511487 1.0371815746634 113 Delta-aminolevulinic acid dehydratase H Delta-aminolevulinic acid dehydratase 249708 1.28735887896014 2.98824087398122 1.0261272968289 1 Glutamate-1-semialdehyde aminotransferase H glutamate-1-semialdehyde 2,1-aminomutase 249709 1.30184042151046 3.060945548114 1.05696157548345 181 Porphobilinogen deaminase H Porphobilinogen deaminase 249710 1.35118634951831 3.25186097324481 1.12355947195773 167 Dihydroorotate dehydrogenase F Dihydroorotate dehydrogenase 249711 1.34157176945441 3.14550534977805 1.04316313154508 543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases HC Dihydroorotate dehydrogenase electron transfer subunit 249712 1.24640027174879 2.96157421105321 1.01997750024973 179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Q Fumarylacetoacetate hydrolase family protein 249713 1.31906541351842 2.93238187000088 1.02843944175115 3388 Uncharacterized protein conserved in archaea S conserved protein 249714 1.30726990176301 2.93636013067594 1.02234429209606 8 Glutamyl- and glutaminyl-tRNA synthetases J Glutamyl-tRNA synthetase 249715 1.25087871531576 2.89147731412082 1.00587594679047 - - - conserved protein 249716 1.31403587708057 3.15934893865741 1.07633981053088 1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-bin L Replication factor-A protein 1 249717 1.31943909734954 3.01545730827303 1.02729081332549 3390 Uncharacterized protein conserved in archaea S conserved protein 249718 1.28805577368093 3.0665703505255 1.07172177747737 111 Phosphoglycerate dehydrogenase and related dehydrogenases HE D-3-phosphoglycerate dehydrogenase 249719 1.25197177759463 2.86430114743924 0.997434838905029 3612 Uncharacterized protein conserved in archaea S conserved protein 249720 1.44043228490954 3.46628516349693 1.08684712668557 1727 Ribosomal protein L18E J LSU ribosomal protein L18E 249721 1.42516263180338 3.36347492383063 1.11294619780253 102 Ribosomal protein L13 J LSU ribosomal protein L13P 249722 1.24577540164573 2.96617515469464 1.05406967733654 103 Ribosomal protein S9 J SSU ribosomal protein S9P 249723 1.35027528576663 3.14053822214715 1.07479195234362 1644 DNA-directed RNA polymerase, subunit N (RpoN/RPB10) K DNA-directed RNA polymerase subunit N 249724 1.53898495824283 3.64484395302431 1.09083621267155 1758 DNA-directed RNA polymerase, subunit K/omega K DNA-directed RNA polymerase subunit K 249725 1.19483665697418 2.85512105420951 0.964596170767228 52 Ribosomal protein S2 J SSU ribosomal protein S2P 249726 1.31869971393269 3.04625164894292 1.02052566821335 1355 Predicted dioxygenase R conserved protein 249727 1.31472835193661 3.17982238845178 1.03487063840185 1577 Mevalonate kinase I Mevalonate kinase 249728 1.28745780248806 3.07780838965291 1.06148822737081 1608 Predicted archaeal kinase R Archaeal Kinase 249729 1.2752361219411 3.02158990919697 1.04987335994496 1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases C Isopentenyl-diphosphate delta-isomerase 249730 1.30550624119579 2.75340971232517 0.875134139281022 - - - hypothetical protein 249731 1.30815437778519 3.02163223079846 1.03432806311926 595 Predicted hydrolase of the metallo-beta-lactamase superfamily R Zn-dependent hydrolase 249732 1.31150130183169 3.01733089137336 1.03496920249553 142 Geranylgeranyl pyrophosphate synthase H Dimethylallyltransferase 249733 1.34616688161843 3.35063129041039 1.01009655821344 - - - hypothetical protein 249734 1.46927805923816 3.32386890403305 0.989816660201165 1943 Transposase and inactivated derivatives L Transposase 249735 1.27327645847277 2.87975629391563 1.00417990261214 574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase G Pyruvate, phosphate dikinase 249736 1.52850773913854 3.77134711589469 1.08979356834032 3277 RNA-binding protein involved in rRNA processing J hypothetical protein 249737 1.37357423514586 3.17425776667235 1.05772768709677 1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB K Transcription initiation factor IIB 249738 1.36788849327418 3.45997764890953 1.12518988191497 1280 Putative threonine efflux protein E conserved protein 249739 1.40322469544919 3.49131471550162 1.16456574289061 - - - hypothetical protein 249740 1.2916958109459 2.93790806059825 1.02545422302923 2520 Predicted methyltransferase R methyltransferase 249741 1.33247581943314 2.91149828900422 0.978544011448083 1225 Peroxiredoxin O Thiol-specific antioxidant protein 249742 1.32794131452431 3.10015011762493 1.0860179956979 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 249743 1.36822624308729 3.31287881601112 1.10587220986983 53 Predicted Co/Zn/Cd cation transporters P Cobalt-zinc-cadmium resistance protein 249744 1.32503882049882 3.15608644409634 1.10014247017317 412 Dienelactone hydrolase and related enzymes Q hypothetical protein 249745 1.33237730942883 3.02682294015172 0.97489435739063 1926 Predicted phosphoribosyltransferases R hypothetical protein 249746 1.28960874372366 2.9728866113841 1.0499591147146 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 249747 1.29499069173004 3.16475244953853 1.09774510785792 786 Na+/glutamate symporter E Sodium/glutamate symport carrier protein 249748 1.37969138771099 2.98295270349102 1.06151948447235 - - - hypothetical protein 249749 1.32897665638731 3.17795435281855 1.08933528915852 - - - hypothetical protein 249750 1.34357499865184 3.13866687766772 1.07988888325749 - - - hypothetical protein 249751 1.4870876986477 3.43697792061466 0.964986698842284 - - - Transposase 249752 1.35027523300376 2.85527078332441 0.904425034198443 3436 Transposase and inactivated derivatives L Transposase 249753 1.27354434124029 2.93474772667735 1.04139086387496 2013 Uncharacterized conserved protein S HTH DNA-binding protein 249754 1.24254868624441 2.72266961467669 0.962891357274265 - - - hypothetical protein 249755 1.37518926248698 3.19265412941874 1.06744885634301 4742 Predicted transcriptional regulator K conserved protein 249756 1.24492466206296 2.64686154826567 0.916759213490763 - - - conserved protein 249757 1.29234563297426 3.00680249581134 1.02376642217407 484 DnaJ-class molecular chaperone with C-terminal Zn finger domain O hypothetical protein 249758 1.37759159987167 3.15787777894158 1.0691961117491 - - - hypothetical protein 249759 1.37001945889456 2.99055526828251 1.06426992172722 1196 Chromosome segregation ATPases D hypothetical protein 249760 1.35503932471377 3.19296801541703 1.1243332697695 2006 Uncharacterized conserved protein S Iron-sulfur cluster-binding protein 249761 1.29589191214548 2.97581482998785 1.02889158759003 - - - conserved protein 249762 1.21309099993433 2.55836661748473 0.909711013391411 234 Co-chaperonin GroES (HSP10) O 10 kDa chaperonin 249763 1.28706356730602 2.93347609261871 1.03439840169153 459 Chaperonin GroEL (HSP60 family) O 60 kDa chaperonin 249764 1.2934407232903 2.99471171921597 1.0271940340473 - - - conserved protein 249765 1.31276742357319 3.17515164156918 1.09571991152183 1738 Uncharacterized conserved protein S Transporter 249766 1.26730678173596 2.5924209617837 0.904686991036782 - - - conserved protein 249767 1.32637847071953 3.04525738484261 1.04847353057968 436 Aspartate/tyrosine/aromatic aminotransferase E Aspartate aminotransferase 249768 1.26086380723975 2.75738573630292 0.960024387590239 - - - hypothetical protein 249769 1.27631779514002 2.69214399613023 0.966864393331562 1592 Rubrerythrin C Rubrerythrin 249770 1.2684070617301 2.82069398476241 1.00379703026182 1379 Uncharacterized conserved protein S conserved protein 249771 1.3002896889793 2.96961748447961 0.998790501871823 2047 Uncharacterized protein (ATP-grasp superfamily) R conserved protein 249772 1.3077125270766 2.900260060589 0.991607155447038 1093 Translation initiation factor 2, alpha subunit (eIF-2alpha) J protein translation initiation factor 2 subunit alpha 249773 1.23038933251019 2.85763895942255 1.01605974345588 2051 Ribosomal protein S27E J SSU ribosomal protein S27E 249774 1.32376249845839 2.75117033899789 0.904846431847562 1631 Ribosomal protein L44E J LSU ribosomal protein L44E 249775 1.32664578676058 2.95216440095916 0.997911768022733 1711 Uncharacterized protein conserved in archaea S conserved protein 249776 1.29742898197345 2.9032338830382 1.03741808585329 1467 Eukaryotic-type DNA primase, catalytic (small) subunit L DNA primase small subunit 249777 1.30947004832685 2.99764262897504 1.00524596610279 1262 Uncharacterized conserved protein S conserved protein 249778 1.33618007904312 2.98306291171223 1.04543615480556 1293 Predicted RNA-binding protein homologous to eukaryotic snRNP K conserved protein 249779 1.26946382447634 2.7306613095031 0.956915585013563 1293 Predicted RNA-binding protein homologous to eukaryotic snRNP K hypothetical protein 249780 1.36315743430242 3.06709201627856 1.04721574170544 1537 Predicted RNA-binding proteins R Cell division protein 249781 1.26442418168724 2.96013028479032 1.03943654862186 - - - conserved protein 249782 1.29859225865025 3.32609907194391 1.12698557066218 4089 Predicted membrane protein S conserved protein 249783 1.27137055397733 2.97482670404508 1.0163874270007 1624 Uncharacterized conserved protein S conserved protein 249784 1.41371665344529 3.04480375170912 0.906763764811353 - - - Transposase 249785 1.27515235969732 2.87526904540741 0.982607846196959 1514 2'-5' RNA ligase J tRNA nucleotidyltransferase 249786 1.28886939543602 2.92566214588674 0.984652601955648 470 ATPase involved in DNA replication L replication factor C subunit 249787 1.2885998871333 2.83470513631541 0.828302758604682 - - - hypothetical protein 249788 1.35861067236125 3.35334737765506 1.09181928181239 2426 Predicted membrane protein S putative small multi-drug export protein 249789 1.25055873289708 2.7926677981736 0.966555715429155 1245 Predicted ATPase, RNase L inhibitor (RLI) homolog R Ferredoxin 249790 1.53376176403467 3.43230104739977 1.11028621942564 2036 Histones H3 and H4 B DNA binding protein 249791 1.2511332373786 2.88400697092513 0.994072407197524 - - - methyltransferase 249792 1.30889317097063 3.00746038337536 1.04632423676187 5016 Pyruvate/oxaloacetate carboxyltransferase C Pyruvate carboxylase subunit B 249793 1.26691944400164 2.91288109911656 1.02810224385214 4770 Acetyl/propionyl-CoA carboxylase, alpha subunit I Pyruvate carboxylase, subunit A 249794 1.31436032761066 3.08133641369289 1.04051236935773 340 Biotin-(acetyl-CoA carboxylase) ligase H biotin--[acetyl-COA-carboxylase] synthetase 249795 1.29940770985165 3.13231591874332 1.01737211812614 - - - conserved protein 249796 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 249797 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 249798 1.32219281287872 2.81126770904992 0.995611386506203 1340 Uncharacterized archaeal coiled-coil protein S Phosphoserine phosphatase 249799 1.25985470668776 2.61886402414375 0.877599751000681 - - - conserved protein 249800 1.27206415195144 2.7733845574701 1.00087177761018 2412 Uncharacterized conserved protein S conserved protein 249801 1.33216801970912 3.01987968103604 1.08125855309977 1241 Predicted ATPase involved in replication control, Cdc46/Mcm family L cell division control protein 249802 1.28112296375451 3.04971874716973 1.01658486738786 565 rRNA methylase J RNA methylase 249803 1.18341573342892 2.55565476591644 0.980524100852816 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C Ferredoxin 249804 1.34612762438092 3.26774773357063 0.974920622448684 - - - conserved protein 249805 1.33354819541818 3.10917158714558 0.949363295007251 3420 Nitrous oxidase accessory protein P conserved protein 249806 1.50544949169074 3.62304251428733 1.04027136147492 - - - hypothetical protein 249807 1.29454209903541 2.95980897457896 1.01380216446599 1251 NAD(P)H-nitrite reductase C Sulfite reductase, assimilatory-type 249808 1.26730127293221 3.0689646807154 1.05605645085734 - - - Heterodisulfide reductase, subunit 249809 1.3071191009378 2.91018576372246 0.994783996153685 247 Fe-S oxidoreductase C Heterodisulfide reductase, subunit 249810 1.27947488158981 2.83985298255738 0.969501487416485 1852 Uncharacterized conserved protein S conserved protein 249811 1.30491937504155 3.03592390284693 1.03897058177565 1852 Uncharacterized conserved protein S conserved protein 249812 1.29334718149772 2.87569486143511 0.978646428326931 644 Dehydrogenases (flavoproteins) C hypothetical protein 249813 1.35324246473505 3.09647049643352 0.985559566871161 - - - hypothetical protein 249814 1.29053670756751 2.9984175662884 1.04786935177452 644 Dehydrogenases (flavoproteins) C Geranylgeranyl reductase 249815 1.59943416240956 3.87694192960117 1.12892537546944 - - - hypothetical protein 249816 1.27784064729201 2.94078897105106 1.0352528632475 4008 Predicted metal-binding transcription factor K hypothetical protein 249817 1.26120812726792 2.90853628173705 1.0130980718248 1767 Triphosphoribosyl-dephospho-CoA synthetase H conserved protein 249818 1.30519932247135 2.96494982769469 1.01349794352783 2457 Uncharacterized conserved protein S conserved protein 249819 1.26840532023636 2.93178294535208 0.985695542410319 1036 Archaeal flavoproteins C Archaeal flavoprotein 249820 1.29832756355949 3.02414911778409 1.05466058305124 4608 ABC-type oligopeptide transport system, ATPase component E Dipeptide/oligopeptide ABC transporter, ATP-binding protein 249821 1.34175299517711 3.14099151781767 1.08669979296059 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP Dipeptide/oligopeptide ABC transporter, ATP-binding protein 249822 1.32919738844426 3.22003550432929 1.12541011835982 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Dipeptide/oligopeptide ABC transporter, permease 249823 1.28500339969715 3.14431248132796 1.08655537928967 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Dipeptide/oligopeptide ABC transporter, permease 249824 1.23674561800709 2.81550403853475 1.00656672308393 747 ABC-type dipeptide transport system, periplasmic component E Dipeptide/oligopeptide binding protein 249825 1.27450438917043 2.85237074641165 0.986191852608877 613 Predicted metal-dependent phosphoesterases (PHP family) R conserved protein 249826 1.32988960751044 2.84501521139006 0.964127159444657 - - - conserved protein 249827 1.44593721929924 3.53015296223945 1.13169209616328 2814 Arabinose efflux permease G Transporter 249828 1.33516635536338 2.92489857638619 0.965306244197456 1846 Transcriptional regulators K transcriptional regulator, MarR family 249829 1.28839561043189 2.80599302551509 0.961868984469818 - - - conserved protein 249830 1.33281053025169 2.93462622169361 0.987919236859874 - - - conserved protein 249831 1.28292168666028 3.14079979824524 1.07673503545702 - - - hypothetical protein 249832 1.47413891084434 3.04766799037948 1.00141344039455 - - - conserved protein 249833 1.46907779181458 3.1382705819925 0.986618711667724 - - - conserved protein 249834 1.30078694757284 2.92075757377454 0.992717092733478 - - - conserved protein 249835 1.29184218745659 3.03606858152933 1.0650070071426 433 Predicted ATPase R conserved protein 249836 1.26478814624405 2.94212392618259 1.03796409986304 163 3-polyprenyl-4-hydroxybenzoate decarboxylase H Vanillate decarboxylase protein 249837 1.27004831115784 3.07994326852083 1.01725596030031 - - - conserved protein 249838 1.31991642051009 2.9560154727854 1.02587897796908 1078 HD superfamily phosphohydrolases R phosphohydrolase 249839 1.30498404507741 3.09423362730498 1.04164957822832 391 Uncharacterized conserved protein S methyltransferase 249840 1.25793544062412 2.86743226556968 0.98859458902621 5643 Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E R conserved protein 249841 1.34226723207797 3.24641406760215 1.08828301215201 503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins F Purine phosphoribosyltransferase 249842 1.32337173961978 3.04203340677093 1.06204190006792 1736 Diphthamide synthase subunit DPH2 J Diphthamide synthase subunit 249843 1.28022430116839 2.90687385175498 0.996317185542536 2263 Predicted RNA methylase J methyltransferase 249844 1.31494755976451 2.99295435919207 1.04950664131349 1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) J putative RNA-binding protein 249845 1.21896338217554 2.81292564710817 1.02570258062697 1761 DNA-directed RNA polymerase, subunit L K DNA-directed RNA polymerase subunit L 249846 1.28119825839249 2.96115920990527 1.04230212177331 1103 Archaea-specific pyridoxal phosphate-dependent enzymes R conserved protein 249847 1.30721493055461 2.78251181629937 0.982279685155748 - - - conserved protein 249848 1.2734052502567 2.8307675082482 1.00632829437301 4739 Uncharacterized protein containing a ferredoxin domain S conserved protein 249849 1.46862080292894 3.30169712053291 0.97954379858167 1943 Transposase and inactivated derivatives L Transposase 249850 1.29201276612105 2.87054744527521 1.0050991853521 19 Diaminopimelate decarboxylase E Diaminopimelate decarboxylase 249851 1.43093780475831 3.09863707169932 0.921962093082073 - - - Nonspecific acid phosphatase precursor 249852 1.43700307286772 3.32096532202175 0.980919860043076 - - - hypothetical protein 249853 1.36539825456358 3.05019792056709 1.01198927807827 5421 Transposase L Transposase 249854 1.51281484888237 3.55908967106473 1.11517018921425 3247 Uncharacterized conserved protein S conserved protein 249855 1.39808616491477 3.30365316769514 1.10843826258884 3264 Small-conductance mechanosensitive channel M conserved protein 249856 1.3555778913895 3.37807489723461 1.16160332386226 25 NhaP-type Na+/H+ and K+/H+ antiporters P Na(+)/H(+) antiporter 249857 1.37723515096543 3.08078968462125 1.04898640102937 3119 Arylsulfatase A and related enzymes P Arylsulfatase 249858 1.37750420342231 3.05006218860757 1.04201551557531 641 Arylsulfatase regulator (Fe-S oxidoreductase) R putative transcriptional regulator 249859 1.29386106926852 2.91559377733561 1.03889780390575 1796 DNA polymerase IV (family X) L DNA polymerase beta 249860 1.32040085943941 2.97460712955306 1.04080628136952 1793 ATP-dependent DNA ligase L ATP-dependent DNA ligase 249861 1.25054054179383 2.85261407055019 0.971039306628554 2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism Q Phenylacetic acid degradation protein 249862 1.27339681826115 2.96023044259226 1.02830963484664 - - - hypothetical protein 249863 1.33943420702772 3.18683313253557 1.06639944370606 - - - Potassium channel protein 249864 1.33137234440795 3.22955451959112 1.12814909375893 - - - hypothetical protein 249865 1.34824256575763 3.19120017801739 1.09688134789544 - - - hypothetical protein 249866 1.18464250103516 2.35502647151967 0.844442194564077 - - - hypothetical protein 249867 1.31846144848855 3.07654561730178 1.03048438070802 1247 Sortase and related acyltransferases M hypothetical protein 249868 1.34214593169921 3.04080347029337 1.05322005292418 1846 Transcriptional regulators K transcriptional regulator, MarR family 249869 1.38939255873882 3.3980179709168 1.08059320268718 607 Rhodanese-related sulfurtransferase P hypothetical protein 249870 1.41493813164477 3.49109283362211 1.11917277378579 - - - hypothetical membrane spanning protein 249871 1.2880973528534 2.76191531264967 0.957902868137167 - - - conserved protein 249872 1.30725818422849 3.01854432534323 1.03993975756857 1335 Amidases related to nicotinamidase Q Isochorismatase 249873 1.35310541195398 3.26137768642255 1.14319331132495 2020 Putative protein-S-isoprenylcysteine methyltransferase O hypothetical protein 249874 1.27252111236125 3.06732687566512 1.07499395680893 475 Kef-type K+ transport systems, membrane components P Glutathione-regulated potassium-efflux system protein 249875 1.26922787041514 2.98946398759454 1.02989621378103 424 Nucleotide-binding protein implicated in inhibition of septum formation D Maf protein 249876 1.3068179413044 2.92745844892095 1.00025945979165 215 Cysteinyl-tRNA synthetase J Cysteinyl-tRNA synthetase 249877 1.31715026412199 2.99952276403425 1.03821441821211 - - - hypothetical protein 249878 1.26249735403123 2.93828825532623 1.02637084162343 1750 Archaeal serine proteases R ATP-dependent protease La 249879 1.3128679495139 3.06351733142755 1.03118532024595 1407 Predicted ICC-like phosphoesterases R hypothetical protein 249880 1.32709477860661 3.00454991939871 1.0593864525886 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 249881 1.28690079115622 2.84138358340516 0.982355217537479 1190 Lysyl-tRNA synthetase (class II) J Lysyl-tRNA synthetase 249882 1.31845974674514 3.03503036209491 1.06982218760186 1201 Lhr-like helicases R ATP-dependent RNA helicase 249883 1.41200947445242 3.14843098782828 0.948386600815913 - - - hypothetical protein 249884 1.36844162564142 2.96407233470334 0.997230155335017 1598 Uncharacterized conserved protein S hypothetical protein 249885 1.3789822102304 3.11419941963781 1.05366571961655 1669 Predicted nucleotidyltransferases R nucleotidyltransferase 249886 1.37920863143406 2.83007025956387 0.941226037068971 - - - hypothetical protein 249887 1.32208647164181 2.80415607842867 0.923304828151376 - - - hypothetical protein 249888 1.37109967374117 2.92830372472179 1.01300500675482 1598 Uncharacterized conserved protein S hypothetical protein 249889 1.33009199021645 3.0760102200996 1.07740536548739 1724 Predicted periplasmic or secreted lipoprotein N hypothetical protein 249890 1.39544210333913 3.20723588159014 0.966102073578937 3339 Uncharacterized conserved protein S hypothetical protein 249891 1.30417105267436 3.0929652555816 1.06387052956599 - - - hypothetical protein 249892 1.25151077901817 3.12618254767986 1.10545660949755 3420 Nitrous oxidase accessory protein P Cell surface glycoprotein 249893 1.20559352370748 2.6331155727078 0.919888617795947 1247 Sortase and related acyltransferases M phosphinothricin acetyltransferase 249894 1.3041658516841 3.01175470494698 1.02442491791975 - - - hypothetical protein 249895 1.35409535206091 3.06959069876866 0.927664222992699 3547 Transposase and inactivated derivatives L Transposase 249896 1.28428295921135 3.01252671425681 1.06483391419446 642 Signal transduction histidine kinase T sensory transduction protein kinase 249897 1.32904802075478 3.11191787701219 1.08754914740806 407 Uroporphyrinogen-III decarboxylase H Methylcobalamin:coenzyme M methyltransferase 249898 1.31384464980095 3.2478262621206 1.106338691274 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER integral membrane protein 249899 1.32397830379535 2.94943379122125 1.00803997811849 4997 Uncharacterized conserved protein S hypothetical protein 249900 1.3071528583351 2.81388616914295 0.974474701338071 - - - Acetyltransferase 249901 1.25959737009167 2.91962281712046 1.00132600450656 823 Periplasmic component of the Tol biopolymer transport system U conserved protein 249902 1.33039902419901 2.85877830775823 0.999029283258187 1739 Uncharacterized conserved protein S hypothetical protein 249903 1.16234490661495 2.29083977690202 0.598690527120599 - - - hypothetical protein 249904 1.26377012899219 2.81178064502469 0.930674753499519 834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain ET Glutamine-binding protein 249905 1.36085422074825 3.36268839627217 1.129722123261 765 ABC-type amino acid transport system, permease component E Glutamine transporter, permease protein 249906 1.2855305614035 2.94535010919119 1.00006445989062 1126 ABC-type polar amino acid transport system, ATPase component E Glutamine transporter, ATP-binding protein 249907 1.29565273993657 3.05670758198529 1.06275945186742 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H polyprenyltransferase 249908 1.3197234363926 2.98370175841965 1.02168494106106 - - - conserved protein 249909 1.30144373181525 2.95422400799415 1.02290506979922 1533 DNA repair photolyase L Transporter 249910 1.22658866559569 2.6193613863078 0.936032321611822 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S hypothetical protein 249911 1.27119723003436 2.92587821169773 1.03288905940743 438 Glycosyltransferase M glycosyltransferase 249912 1.34955423433772 3.42568225238227 1.13962810014251 392 Predicted integral membrane protein S integral membrane protein 249913 1.33752834990204 3.03468432173129 1.04265669296708 1453 Predicted oxidoreductases of the aldo/keto reductase family R oxidoreductase, ALDO/KETO reductase family 249914 1.26144751223954 2.78541153592276 0.953334138719975 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H methyltransferase 249915 1.3308857530757 2.93312734908932 1.04219154871648 753 Catalase P Catalase 249916 1.31897398698968 2.92874067954031 1.0465779641519 - - - hypothetical protein 249917 1.32531823230477 3.22240572858307 1.06123098216687 53 Predicted Co/Zn/Cd cation transporters P Cobalt-zinc-cadmium resistance protein 249918 1.31455287564309 3.17142195394575 1.12193678758733 53 Predicted Co/Zn/Cd cation transporters P Cobalt-zinc-cadmium resistance protein 249919 1.28114131370698 2.89532747906691 1.0173960453616 822 NifU homolog involved in Fe-S cluster formation C NifU protein 249920 1.31074701585981 3.04747442720429 1.06641218298557 1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes E Cysteine desulfurase NifS 249921 1.33400471144081 2.96770647403394 1.01894951580956 2210 Uncharacterized conserved protein S hypothetical protein 249922 1.30374940932862 2.86203110113651 1.01356036342098 425 Predicted redox protein, regulator of disulfide bond formation O hypothetical transcriptional regulatory protein 249923 1.24441245343037 2.80703911938251 0.936355920990855 537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases FGR Hit-like protein 249924 1.36352906086489 3.29648840073436 1.08668559951351 4095 Uncharacterized conserved protein S hypothetical protein 249925 1.27617244190122 3.35232019131474 1.10239481317643 - - - conserved protein 249926 1.275782951072 2.98922740015794 1.05191524210044 1572 Uncharacterized conserved protein S hypothetical protein 249927 1.31386356057271 2.93106919693309 1.02939606324218 - - - conserved protein 249928 1.27556160523745 2.8542375400581 1.00027614955838 162 Tyrosyl-tRNA synthetase J Tyrosyl-tRNA synthetase 249929 1.28526875598761 2.88456499622532 0.976945888915006 4021 Uncharacterized conserved protein S hypothetical protein 249930 1.31061324493813 3.06346011471669 1.04384740672655 1873 Uncharacterized conserved protein S hypothetical protein 249931 1.24965429573235 2.94667009925189 0.997093578621328 39 Malate/lactate dehydrogenases C Malate dehydrogenase 249932 1.27102855651455 2.88443694315274 1.00796508348793 3359 Predicted exonuclease L hypothetical protein 249933 1.29977834196176 2.98507273095037 1.04111098331188 2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes GR hypothetical protein 249934 1.30375670305999 3.22271236999994 1.09718117226444 1693 Uncharacterized protein conserved in archaea S hypothetical protein 249935 1.26865903658263 2.90355011345404 1.00427962866499 608 Single-stranded DNA-specific exonuclease L Single-stranded-DNA-specific exonuclease recJ 249936 1.2701865426835 2.8612421804646 0.969042237273407 - - - conserved protein 249937 1.32724329621434 2.92990174062354 0.957064193300445 - - - hypothetical protein 249938 1.25117349228537 2.87759357954913 1.00797354529502 - - - conserved protein 249939 1.27201166920121 2.84190011463429 0.998219026074209 1243 Histone acetyltransferase KB histone acetyltransferase 249940 1.37561483716772 3.01309395232116 0.995686836832104 - - - conserved protein 249941 1.23281280003091 2.78545647208776 0.841686432909907 - - - conserved protein 249942 1.29676318374584 3.13481954085201 1.039933571463 - - - conserved protein 249943 1.26812388454063 2.90397309551971 1.01102665456666 2218 Formylmethanofuran dehydrogenase subunit C C tungsten formylmethanofuran dehydrogenase, subunit C 249944 1.24691168693397 2.87950255817913 0.963341914429979 1229 Formylmethanofuran dehydrogenase subunit A C tungsten formylmethanofuran dehydrogenase, subunit A 249945 1.27337285801543 2.96712522073727 1.04038486259153 1029 Formylmethanofuran dehydrogenase subunit B C tungsten formylmethanofuran dehydrogenase, subunit B 249946 1.22335136556639 2.71709112129409 0.985169636726717 1153 Formylmethanofuran dehydrogenase subunit D C tungsten formylmethanofuran dehydrogenase, subunit D 249947 1.33259508764271 3.04117067881198 1.06853508828602 2015 Alkyl sulfatase and related hydrolases Q Alkyl sulfatase 249948 1.27882373324651 3.1430886269477 1.09060116765501 3291 FOG: PKD repeat R conserved protein 249949 1.27675304733679 2.6600796482281 0.967506493914782 - - - hypothetical cytosolic protein 249950 1.35917261089927 2.77998938053671 0.914893613880681 - - - hypothetical cytosolic protein 249951 1.3071545623061 3.08601504679061 1.06260357147803 704 Phosphate uptake regulator P putative regulatory protein 249952 1.36586678402222 3.06908147713671 0.930418968725846 - - - hypothetical protein 249953 1.3045804301408 2.89416509162369 0.905630655911992 - - - conserved protein 249954 1.33607540563675 3.03201793312063 1.02988438390392 - - - hypothetical protein 249955 1.29293085206822 2.97624130799279 1.05252031711513 - - - hypothetical protein 249956 1.36060680890012 3.30380919694917 1.11541680898658 - - - hypothetical protein 249957 1.37905082117411 3.24197778581817 1.01473140695562 - - - hypothetical protein 249958 1.31017623256915 3.30756182640763 1.10935730385517 - - - ABC transporter, permease protein 249959 1.29702367404966 3.02263988516938 1.02573148420515 1131 ABC-type multidrug transport system, ATPase component V ABC transporter, ATP-binding protein 249960 1.30889285887007 3.27940384010872 1.12723155728887 619 ABC-type cobalt transport system, permease component CbiQ and related transporters P Cobalt transport protein 249961 1.28358674768836 2.99691358406037 1.05939237725526 1122 ABC-type cobalt transport system, ATPase component P Cobalt transport ATP-binding protein 249962 1.32137888702564 3.25999406864356 1.11935361751544 - - - conserved protein 249963 1.29057165731236 2.93671295524338 1.05500827647557 1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases H Cobalamin biosynthesis protein 249964 1.25147142062325 2.90662284211984 1.03706041978749 1520 FOG: WD40-like repeat S hypothetical protein 249965 1.27066158380138 3.04831562991497 1.07429772276799 - - - hypothetical protein 249966 1.31112112050687 3.05647133108169 1.04804176583351 - - - hypothetical protein 249967 1.27622402344485 3.00077783371278 1.064008978866 - - - conserved protein 249968 1.29472466547968 2.93143249454145 1.03538849096244 1239 Mg-chelatase subunit ChlI H Magnesium-chelatase subunit 249969 1.28919572330206 2.97450666061942 1.06495870892323 417 DNA polymerase elongation subunit (family B) L DNA polymerase delta catalytic subunit 249970 1.26513890667923 3.05072024293921 1.05381205089312 226 ABC-type phosphate transport system, periplasmic component P Phosphate-binding protein 249971 1.32641023899503 3.31429232251725 1.13993374087808 573 ABC-type phosphate transport system, permease component P Phosphate transporter, permease protein 249972 1.39394375263926 3.48277930215959 1.13470498648238 581 ABC-type phosphate transport system, permease component P Phosphate transporter, permease protein 249973 1.40790412268156 3.50552150646784 1.09468315093019 581 ABC-type phosphate transport system, permease component P Phosphate transporter, permease protein 249974 1.30568173574553 3.01316769157293 1.00785567152996 1117 ABC-type phosphate transport system, ATPase component P Phosphate transporter, ATP-binding protein 249975 1.28745688924067 2.96461577924094 0.989025002739435 704 Phosphate uptake regulator P Phosphate transport system protein 249976 1.31483170797988 3.02606046270104 1.04066372471214 44 Dihydroorotase and related cyclic amidohydrolases F Dihydroorotase 249977 1.28299077600909 2.90860188966741 0.981093134551186 1094 Predicted RNA-binding protein (contains KH domains) R putative RNA-binding protein 249978 1.31573574533274 2.91678206280632 1.00200989151719 1718 Serine/threonine protein kinase involved in cell cycle control TD Serine/threonine protein kinase 249979 1.29168842630726 2.97639639076192 1.01870568861677 361 Translation initiation factor 1 (IF-1) J translation initiation factor 1A 249980 1.29036608721244 2.94145210033701 1.03237398488304 1308 Transcription factor homologous to NACalpha-BTF3 K hypothetical protein 249981 1.22931636042338 2.72119194140304 0.967381117375702 316 Uncharacterized conserved protein S HesB protein 249982 1.30020746338501 2.89753617566829 1.01355810933171 - - - conserved protein 249983 1.28110786858837 3.01702433511126 1.05601980196384 3408 Glycogen debranching enzyme G conserved protein 249984 1.36944486756413 3.0306387211846 0.985742353581602 139 Phosphoribosyl-AMP cyclohydrolase E Phosphoribosyl-AMP cyclohydrolase 249985 1.33496864494177 3.12418785862526 1.08871505342877 1855 ATPase (PilT family) R twitching mobility (PilT) related protein 249986 1.36014455539466 3.32383075914247 1.12180051111319 - - - conserved protein 249987 1.3216244797193 3.42988537420371 1.13817447982025 - - - transporter, LysE family 249988 1.26532600884057 3.14906045669304 1.02653786452613 - - - conserved protein 249989 1.31798291949445 3.21022755590129 1.01576005184527 - - - conserved protein 249990 1.51387675482939 3.63081353774266 1.01140431522726 - - - hypothetical protein 249991 1.3164737050193 3.0589536226704 0.892692545666012 - - - hypothetical protein 249992 1.39833235673976 3.03490357413983 0.857247538868057 - - - hypothetical protein 249993 1.40173661549446 3.05610848203503 0.927718864232756 1413 FOG: HEAT repeat C hypothetical protein 249994 1.58265835390968 3.39203815092623 1.06520398239939 - - - conserved protein 249995 1.29995416509015 3.03006626611801 1.06228853247313 118 Glutamine amidotransferase E Amidotransferase hisH 249996 1.28571219172774 3.06235924697682 1.05223736452743 1973 Hydrogenase maturation factor O Hydrogenase expression/formation protein 249997 1.29241084988382 3.0520272764858 1.04907263129441 1030 Membrane-bound serine protease (ClpP class) O nodulation protein 249998 1.30500638978752 3.01090964913506 1.06879992223299 330 Membrane protease subunits, stomatin/prohibitin homologs O stomatin-like protein 249999 1.28256025736807 2.94677881347111 1.04312133998766 1107 Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain L conserved protein 250000 1.30734606108171 3.12080632597606 1.04917092063142 856 Orotate phosphoribosyltransferase homologs F Orotate phosphoribosyltransferase 250001 1.3707248068146 3.02433835189923 1.04811022681507 1439 Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module R conserved protein 250002 1.2807543329948 2.88849847996962 0.996819506055452 2043 Uncharacterized protein conserved in archaea S conserved protein 250003 1.18876160743741 2.71669583214234 0.930847544760973 - - - conserved protein 250004 1.35477958047712 3.26253347799676 1.11084299909546 2007 Ribosomal protein S8E J SSU ribosomal protein S8E 250005 1.3196346835984 3.0301225443378 1.01708141655231 1522 Transcriptional regulators K transcriptional regulatory protein, AsnC family 250006 1.29301708751597 3.02378380669517 1.07212094627769 436 Aspartate/tyrosine/aromatic aminotransferase E Aspartate aminotransferase 250007 1.31069121569384 2.83276374119737 0.988316763510845 3355 Predicted transcriptional regulator K archaeal transcriptional regulator 250008 1.29224174881699 2.88946866183304 1.00393274688168 1549 Queuine tRNA-ribosyltransferases, contain PUA domain J hypothetical protein 250009 1.32480917918353 2.95458665039015 1.014094427807 - - - conserved protein 250010 1.21479119565578 2.64701068220827 0.967934243427806 - - - conserved protein 250011 1.28410218188186 3.10382011990002 1.0435984812582 - - - Trimethylamine Permease 250012 1.2721667994948 2.83912984487216 1.0073953780588 5012 Predicted cobalamin binding protein R dimethylamine corrinoid protein 250013 1.26568303123672 2.89173529681707 0.9825462626939 5598 Trimethylamine:corrinoid methyltransferase H Trimethylamine:corrinoid methyltransferase 250014 1.22281448671758 2.84945016170173 0.971109574381524 5598 Trimethylamine:corrinoid methyltransferase H Trimethylamine:corrinoid methyltransferase 250015 1.30256573802944 2.93612262581388 0.987233657966945 - - - dimethylamine:corrinoid methyltransferase 250016 1.29203908270304 2.9645162791375 1.02922919941948 - - - dimethylamine:corrinoid methyltransferase 250017 1.33345395746573 3.00021317639189 1.0446480168428 5012 Predicted cobalamin binding protein R dimethylamine corrinoid protein 250018 1.28731713296905 2.75971296089617 0.918698677000452 - - - conserved protein 250019 1.30258528828724 2.97842131247634 1.03881475469919 719 ABC-type transport system involved in Fe-S cluster assembly, permease component O ABC transporter, ATP-binding protein 250020 1.33306002279138 3.10562458496167 1.04827252216746 396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component O ABC transporter, ATP-binding protein 250021 1.26606656731765 2.95581221364985 1.02017347679626 2266 GTP:adenosylcobinamide-phosphate guanylyltransferase H putative nucleotidyltransferase 250022 1.32896900833138 3.21880744825511 1.11797633113519 368 Cobalamin-5-phosphate synthase H Cobalamin [5'-phosphate] synthase 250023 1.29439475329717 2.93128296043879 1.01207562101285 1267 Phosphatidylglycerophosphatase A and related proteins I hypothetical protein 250024 1.33274941077262 3.20779908542677 1.09409755919706 1270 Cobalamin biosynthesis protein CobD/CbiB H CbiB protein 250025 1.25613111578129 2.83209602033322 0.991417505504061 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E histidinol-phosphate aminotransferase 250026 1.34301279612664 3.07100706835009 1.05732941933829 124 Histidyl-tRNA synthetase J Histidyl-tRNA synthetase 250027 1.39438365995387 3.37240895940975 1.07798218304886 - - - conserved protein 250028 1.30454120296479 2.98695403216674 1.0241900842592 - - - conserved protein 250029 1.28474476458857 3.0374417255385 1.01983970157145 - - - conserved protein 250030 1.29730164996835 3.0649730687651 1.01606392379391 - - - conserved protein 250031 1.2128236529277 2.77131148444666 0.957607353165602 184 Ribosomal protein S15P/S13E J SSU ribosomal protein S15P 250032 1.37727689911291 3.23503035346878 1.05937471232124 1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components PH Iron(III) dicitrate transport ATP-binding protein 250033 1.31826420692888 3.32200333459589 1.12493056224059 609 ABC-type Fe3+-siderophore transport system, permease component P Iron(III) dicitrate transport system permease protein 250034 1.29005304503627 2.98124825732552 1.0468793115102 614 ABC-type Fe3+-hydroxamate transport system, periplasmic component P Iron(III) dicitrate-binding protein 250035 1.27086208605094 2.95632955701467 1.01906883890591 157 Nicotinate-nucleotide pyrophosphorylase H nicotinate-nucleotide pyrophosphate carboxylating 250036 1.28146524252071 2.99661156000012 1.02654048627215 - - - conserved protein 250037 1.26851811326602 3.0473832381459 1.03997925861713 1712 Predicted dinucleotide-utilizing enzyme R putative dinucleotide-utilizing enzyme 250038 1.29604872743896 2.93525414659834 0.97800876308463 379 Quinolinate synthase H Quinolinate synthetase A 250039 1.2802058540699 2.91428913735457 1.00204451617853 - - - conserved protein 250040 1.34297374927966 3.29432372395901 1.11100574354402 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H 4-hydroxybenzoate octaprenyltransferase 250041 1.30714433528135 2.98755757568347 1.02649653444712 1812 Archaeal S-adenosylmethionine synthetase E S-adenosylmethionine synthetase 250042 1.32639647779819 2.93665468575706 1.01259416976985 1458 Predicted DNA-binding protein containing PIN domain R conserved protein 250043 1.25572544545234 2.72870647818227 0.898353558322497 - - - conserved protein 250044 1.24658676434362 2.78366023001866 0.971474647684476 3118 Thioredoxin domain-containing protein O Thioredoxin 250045 1.3251244568286 3.25623180814188 1.09374844145445 390 ABC-type uncharacterized transport system, permease component R ABC transporter, ATP-binding protein 250046 1.30208928275009 2.95374065748759 1.00169201198094 2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain V ABC transporter, ATP-binding protein 250047 1.24437865558487 2.90628248292327 1.00205458630264 1899 Deoxyhypusine synthase O deoxyhypusine synthase 250048 1.32507996109332 3.04205585411469 1.03348878102554 284 Orotidine-5'-phosphate decarboxylase F Orotidine 5'-phosphate decarboxylase 250049 1.33185399081649 3.07765160793317 1.01240474252493 1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) C CO dehydrogenase/acetyl-COA synthase gamma subunit 250050 1.30223019927871 2.99878165559437 0.991824981669817 2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein) C CO dehydrogenase/acetyl-COA synthase delta subunit 250051 1.32776398161422 3.0324853533425 1.02303933619863 3640 CO dehydrogenase maturation factor D Nitrogenase iron protein 250052 1.24421845440234 2.73382946063249 0.863133177300643 1614 CO dehydrogenase/acetyl-CoA synthase beta subunit C CO dehydrogenase/acetyl-COA synthase beta subunit 250053 1.26680117862821 2.96074531757744 0.995944139388469 1880 CO dehydrogenase/acetyl-CoA synthase epsilon subunit C CO dehydrogenase/acetyl-COA synthase epsiolon subunit 250054 1.32558498545744 2.98853256447948 0.976899317370068 1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit C CO dehydrogenase/acetyl-COA synthase alpha subunit 250055 1.41229302395637 3.11374376455162 1.01006540328589 1342 Predicted DNA-binding proteins R HTH DNA-binding protein 250056 1.3149483589666 2.97946355341236 1.04107859791174 3264 Small-conductance mechanosensitive channel M putative transport channel protein 250057 1.2866967858264 2.81046626654762 0.995748622296104 3640 CO dehydrogenase maturation factor D CODH nickel-insertion accessory protein 250058 1.29552516930851 2.99658312610353 1.04147763447732 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C Indolepyruvate oxidoreductase, subunit 250059 1.3116390804061 3.13823540900922 1.08022395890268 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C Indolepyruvate oxidoreductase, subunit 250060 1.28127846825312 3.07908716190465 1.03837829027402 5652 Predicted integral membrane protein S hypothetical protein 250061 1.27785585141539 3.16244782221178 1.07409243748032 472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase M UDP-N-Acetylglucosamine-1-phosphate transferase 250062 1.32122940579894 3.32115825905931 1.0756335026029 - - - hypothetical protein 250063 1.25341048240455 3.04395985001627 1.05060889381654 - - - conserved protein 250064 1.37682336626441 3.23404055724407 0.906362372546745 3594 Fucose 4-O-acetylase and related acetyltransferases G hypothetical protein 250065 1.40595419368301 3.159283766218 0.93049438612893 2120 Uncharacterized proteins, LmbE homologs S conserved protein 250066 1.37278694380685 3.34940600213154 1.03292377353104 2244 Membrane protein involved in the export of O-antigen and teichoic acid R Heteropolysaccharide repeat unit export protein 250067 1.37948095959609 3.21215554379819 0.955742495495195 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyltransferase 250068 1.35504800957706 3.13039804319965 0.990632777920979 - - - putative methyltransferase 250069 1.38339524352831 3.24356234367028 0.915818503534172 3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation G conserved protein 250070 1.34278368433759 3.02597923192785 0.888432938414537 438 Glycosyltransferase M putative glycosyltransferase 250071 1.34134987084528 3.00534753088257 0.931581664562477 438 Glycosyltransferase M putative glycosyltransferase 250072 1.37121419554451 3.09572152907959 0.924497647236619 438 Glycosyltransferase M glycosyltransferase 250073 1.42120329142435 3.43284717666583 1.04854991126342 - - - conserved protein 250074 1.30504744579621 2.98193747759207 0.979790357375299 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyltransferase 250075 1.33543760336263 3.00392369931979 1.00617785298647 1817 Uncharacterized protein conserved in archaea S conserved protein 250076 1.31329291918758 3.18198958877965 1.06258271624436 110 Acetyltransferase (isoleucine patch superfamily) R galactoside-O-acetyltransferase 250077 1.26804568111539 2.83947064779235 0.995522876067403 2348 Uncharacterized protein involved in methicillin resistance V hypothetical protein 250078 1.28143523565508 2.85048133823235 0.98965013543382 - - - hypothetical protein 250079 1.30359184301019 3.15999964832926 1.10527079563625 - - - hypothetical protein 250080 1.29187446852706 3.06487139287027 1.076304729566 501 Zn-dependent protease with chaperone function O protease HTPX-like protein 250081 1.39950723594222 3.33674409237073 1.03998265291165 - - - hypothetical protein 250082 1.30486396219635 3.11627824010762 1.11583619759392 4743 Predicted membrane protein S hypothetical protein 250083 1.31121087367226 3.50910753284386 1.14497139591745 - - - hypothetical protein 250084 1.35245348901447 3.37355561270155 1.07296712023894 - - - hypothetical protein 250085 1.31414061473624 3.17464851317755 1.06866363009091 - - - hypothetical protein 250086 1.30294460546622 3.08342443207999 1.03523673928408 - - - hypothetical protein 250087 1.31136140644175 3.1743736720322 1.10455890933689 2815 Uncharacterized protein conserved in bacteria S putative serine/threonine protein kinase 250088 1.31461682691554 3.01204546177712 1.01567816753547 - - - hypothetical protein 250089 1.30525640346143 3.08072960718869 1.02011864819909 87 Ribosomal protein L3 J LSU ribosomal protein L3P 250090 1.30766452229696 3.08103913058947 1.02851575862196 88 Ribosomal protein L4 J LSU ribosomal protein L4 250091 1.31932754088022 2.91059472249747 1.05316242772148 89 Ribosomal protein L23 J LSU ribosomal protein L23P 250092 1.30601598815208 3.0781614520415 1.03307713766163 90 Ribosomal protein L2 J LSU ribosomal protein L2P 250093 1.30544635639112 2.97016780204572 1.00115254185348 185 Ribosomal protein S19 J SSU ribosomal protein S19P 250094 1.29273917086658 2.95002746521632 1.01918666437331 91 Ribosomal protein L22 J LSU ribosomal protein L22P 250095 1.23118320763624 2.67515852025946 0.903924322355437 92 Ribosomal protein S3 J SSU ribosomal protein S3P 250096 1.3390091945426 3.0603087702285 1.10759232894274 255 Ribosomal protein L29 J LSU ribosomal protein L29P 250097 1.46787012572103 3.45813005515954 1.08888575643638 1588 RNase P/RNase MRP subunit p29 J Ribonuclease P protein subunit P29 250098 1.31934501392175 3.10087187841644 1.04331651857155 186 Ribosomal protein S17 J SSU ribosomal protein S17P 250099 1.31238112274631 2.98103601179963 1.04065737978097 93 Ribosomal protein L14 J LSU ribosomal protein L14P 250100 1.32718397263876 3.14944357754363 1.05882152339243 198 Ribosomal protein L24 J LSU ribosomal protein L24P 250101 1.25289570835378 2.94448351542059 0.990288535165829 1471 Ribosomal protein S4E J SSU ribosomal protein S4E 250102 1.29640649434172 3.0014882298394 1.01593935200172 94 Ribosomal protein L5 J LSU ribosomal protein L5P 250103 1.35233616865128 2.91070558889963 1.02792858797559 199 Ribosomal protein S14 J SSU ribosomal protein S14P 250104 1.31040283530796 3.08790601097451 1.02211750165381 96 Ribosomal protein S8 J SSU ribosomal protein S8P 250105 1.29371079847631 2.91659614931152 0.997966095470223 97 Ribosomal protein L6P/L9E J LSU ribosomal protein L6P 250106 1.30881990449662 2.98089238939482 1.02138000108683 1717 Ribosomal protein L32E J LSU ribosomal protein L32E 250107 1.3564559855467 3.08073072827058 1.02056529672223 2147 Ribosomal protein L19E J LSU ribosomal protein L19E 250108 1.38545515110408 3.24833448478815 1.07295005881982 256 Ribosomal protein L18 J LSU ribosomal protein L18P 250109 1.27200956582616 2.98295188769948 1.03421295207299 98 Ribosomal protein S5 J SSU ribosomal protein S5P 250110 1.29194086400146 2.85060713685954 1.00767403122778 1841 Ribosomal protein L30/L7E J LSU ribosomal protein L30P 250111 1.28927039054681 2.98046635594231 1.0051229526151 200 Ribosomal protein L15 J LSU ribosomal protein L15P 250112 1.34807511706024 3.30383218253512 1.14069648559693 201 Preprotein translocase subunit SecY U protein translocase subunit SecY 250113 1.23830615541241 2.7340778594019 0.976419797259718 563 Adenylate kinase and related kinases F Adenylate kinase 250114 1.29296009255527 3.10603432052598 1.08010625271596 41 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase F Phosphoribosylaminoimidazole carboxylase 250115 1.35723885123033 3.04451085556485 1.03851227057168 - - - conserved protein 250116 1.2074035386819 2.94710175613444 1.00682670232173 663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily R Carbonic anhydrase 250117 1.31465033160423 2.92062609793275 0.928841612498823 1422 Predicted membrane protein S hypothetical protein 250118 1.35331105105834 3.15309630493639 1.01791999659401 1102 Cytidylate kinase F Cytidylate kinase 250119 1.38662136606457 3.26253513183991 1.12421194840184 130 Pseudouridine synthase J tRNA pseudouridine synthase 250120 1.32374023249143 3.02946287415614 1.04241288495417 99 Ribosomal protein S13 J SSU ribosomal protein S13P 250121 1.25010644200836 2.84913074398559 0.94762789648771 522 Ribosomal protein S4 and related proteins J SSU ribosomal protein S4P 250122 1.30060045843378 3.10766726586174 1.06269440492119 100 Ribosomal protein S11 J SSU ribosomal protein S11P 250123 1.33913001571755 3.06704310874486 1.03793867499345 202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K DNA-directed RNA polymerase subunit D 250124 1.27694138164394 3.17672045735252 1.04414550539573 3391 Uncharacterized conserved protein S hypothetical protein 250125 1.46185818623124 3.5909911721049 1.02799855457685 - - - hypothetical protein 250126 1.32948210713507 3.07656606607566 1.01490236578624 663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily R hypothetical protein 250127 1.35876097540892 3.20754296824539 1.0078485645051 - - - hypothetical protein 250128 1.29632639519054 2.97346471354635 1.03988695302177 378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase OK Hydrogenase expression/formation protein 250129 1.30730082189991 2.97298599158398 1.03773533305313 298 Hydrogenase maturation factor O Hydrogenase expression/formation protein 250130 1.5236981430355 3.51782926820217 0.976296233087437 3415 Transposase and inactivated derivatives L Transposase 250131 1.30374888272303 3.02450930521115 0.985820487824839 - - - conserved protein 250132 1.3988418256457 3.01732210760835 0.905646478189587 - - - Transposase 250133 1.51374150925742 3.21630609416654 0.966177475200986 - - - Transposase 250134 1.313170391689 3.01563215823372 0.975291381881438 1740 Ni,Fe-hydrogenase I small subunit C F420-nonreducing hydrogenase II precursor 250135 1.24653654174372 2.96687675517526 0.984494294514595 374 Ni,Fe-hydrogenase I large subunit C F420-nonreducing hydrogenase II, large subunit 250136 1.3389342904633 3.14643376071005 1.08723128853411 2864 Cytochrome b subunit of formate dehydrogenase C F420-nonreducing hydrogenase II, subunit cytochrome B 250137 1.33496988857047 3.21429810669376 1.11088124494566 680 Ni,Fe-hydrogenase maturation factor C Hydrogenase expression/formation protein 250138 1.31403328247563 2.89271055571283 0.977793491251558 4891 Uncharacterized conserved protein S conserved protein 250139 1.40654950981391 3.32145066106361 1.10498334660685 - - - conserved protein 250140 1.30870552547667 2.9974085169688 1.05792604004518 1740 Ni,Fe-hydrogenase I small subunit C F420-nonreducing hydrogenase III precursor, small subunit 250141 1.32355324349553 3.13352771599 1.09059055025607 374 Ni,Fe-hydrogenase I large subunit C F420-nonreducing hydrogenase III, large subunit 250142 1.30561647450441 3.04038202284847 0.987207473522717 2864 Cytochrome b subunit of formate dehydrogenase C F420-nonreducing hydrogenase III, subunit cytochrome B 250143 1.28376371623698 2.83995175261783 1.02158585039307 642 Signal transduction histidine kinase T Two component system histidine kinase 250144 1.32544458502071 3.05780991357044 1.05425421165908 1617 Uncharacterized conserved protein S conserved protein 250145 1.24730364097471 2.72430841469901 0.926483951243443 518 GMP synthase - Glutamine amidotransferase domain F GMP synthase [glutamine-hydrolyzing] 250146 1.32630100029178 3.06629460071195 1.04108103126671 1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins G Fructose-1,6-bisphosphatase 250147 1.33774942270197 3.08796988404418 1.04345561456748 621 2-methylthioadenine synthetase J hypothetical protein 250148 1.21841872897731 2.75949858007961 0.964755692209784 - - - hypothetical protein 250149 1.37690561186227 3.18829647300132 1.06752595010395 2101 TATA-box binding protein (TBP), component of TFIID and TFIIIB K TATA-box binding protein 250150 1.28633998566969 3.04545194573543 1.09360921276875 - - - hypothetical protein 250151 1.32468652415555 3.14445757796605 0.901700583571177 - - - conserved protein 250152 1.33875478399649 3.09892085268524 1.01404104540293 - - - conserved protein 250153 1.30562306255243 3.08831953155348 1.03676497371589 - - - conserved protein 250154 1.28884348371067 2.71811031527848 0.919884804625302 1592 Rubrerythrin C Rubrerythrin 250155 1.32994450574081 3.16758831684474 1.05506363923074 - - - hypothetical protein 250156 1.37391033864361 3.05043682911109 0.882414346162677 - - - conserved protein 250157 1.34749162094437 2.90226478494894 0.93958887952922 3666 Transposase and inactivated derivatives L Transposase 250158 1.33386920728752 3.16544130844502 1.09246638261343 420 DNA repair exonuclease L DNA repair protein 250159 1.34559669004134 2.90134063639835 1.02822871896275 419 ATPase involved in DNA repair L DNA repair protein RAD50 250160 1.29620462304154 2.93175669781263 1.02959262471056 2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-depend C F420-dependent glucose-6-phosphate dehydrogenase 250161 1.28957641540358 2.78164298001492 0.955942301710309 - - - conserved protein 250162 1.28570429943869 2.70455302501715 0.944831888813702 - - - conserved protein 250163 1.42737873526986 3.18136731708444 1.05945570116206 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system specificity subunit 250164 1.3929396008355 3.10579923716987 1.00504765873711 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 250165 1.44545106320717 3.25543450885944 0.928403965362563 - - - hypothetical protein 250166 1.35579391288338 2.95677161190967 0.848720871827176 - - - hypothetical protein 250167 1.37275907280258 3.12838495232192 0.999871396385007 3943 Virulence protein R hypothetical protein 250168 1.37093927521815 3.0376604799453 1.00536255363127 3943 Virulence protein R hypothetical protein 250169 1.3505805278599 3.02165561869212 1.06058494418654 610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V hypothetical protein 250170 1.27847662808407 2.98597745546345 1.03610839039983 462 Phosphoribosylpyrophosphate synthetase FE Ribose-phosphate pyrophosphokinase 250171 1.36043407480142 3.21378998125033 1.07462904338273 315 Molybdenum cofactor biosynthesis enzyme H Molybdenum cofactor biosynthesis protein C 250172 1.29228220973811 2.71211142952666 0.990240215946135 - - - conserved protein 250173 1.2939585305107 3.06999741914701 1.07264596359175 63 Predicted sugar kinase G putative sugar kinase 250174 1.28437030790925 3.02760695803007 1.05537130475378 618 Exopolyphosphatase-related proteins R conserved protein 250175 1.28848135309631 3.09897612177462 1.09804269870965 1287 Uncharacterized membrane protein, required for N-linked glycosylation R Oligosaccharyl transferase 250176 1.4030953677155 3.3150414084223 1.02618322880424 - - - hypothetical protein 250177 1.37936740425762 3.3262144130379 0.915355564864257 1835 Predicted acyltransferases I conserved protein 250178 1.30207380499513 2.88531808170646 0.943557929397383 1216 Predicted glycosyltransferases R putative glycosyltransferase 250179 1.32132817645373 3.01458137251861 0.963103527269562 1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component GM Polysaccharide ABC transporter, ATP-binding protein 250180 1.48646620034731 3.646064476628 1.17658770786565 1682 ABC-type polysaccharide/polyol phosphate export systems, permease component GM Polysaccharide ABC transporter, permease protein 250181 1.33990478994855 3.15922428866109 1.07463167776246 1209 dTDP-glucose pyrophosphorylase M Glucose-1-phosphate thymidylyltransferase 250182 1.31275087824111 3.00393407405964 0.978027425875508 1215 Glycosyltransferases, probably involved in cell wall biogenesis M conserved protein 250183 1.33492156015765 2.98100265386744 1.01870270573215 438 Glycosyltransferase M Transposase 250184 1.34722358480717 3.09231410608325 1.03235408749486 2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase H hypothetical protein 250185 1.28347814047109 3.17424715784728 1.06920400789422 - - - hypothetical protein 250186 1.26163072327751 2.91159533144362 0.974114358658469 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase 250187 1.30655156723635 2.93226971277075 1.02572637201721 438 Glycosyltransferase M Galactosyltransferase 250188 1.29815014827352 3.0473919592397 1.06926775081729 463 Glycosyltransferases involved in cell wall biogenesis M Dolichyl-phosphate glucose synthetase 250189 1.33026614119314 3.11305682575785 1.0515149701474 655 Multimeric flavodoxin WrbA R Trp repressor binding protein 250190 1.35062303512682 3.17162373722215 1.09528676051852 3387 Glucoamylase and related glycosyl hydrolases G Glucoamylase 250191 1.39308662319543 3.25685689071748 1.07001349338074 3387 Glucoamylase and related glycosyl hydrolases G Glucoamylase 250192 1.29381586525778 2.82456091800242 0.974614019038131 - - - Acetyltransferase 250193 1.3139308922493 2.97413005206872 1.01260861320171 1473 Metal-dependent amidase/aminoacylase/carboxypeptidase R putative amidohydrolase 250194 1.29718976903402 2.93939126577016 1.04759772776845 1665 Uncharacterized protein conserved in archaea S conserved protein 250195 1.43994496497845 3.13039752484016 0.980130405605463 - - - Transposase 250196 1.41848330697386 3.18622632618551 0.945241958719231 - - - Transposase 250197 1.35670891339964 3.06836271391474 0.965232710616746 - - - Transposase 250198 1.24025508449985 2.9918580142196 1.04296801028037 3291 FOG: PKD repeat R conserved protein 250199 1.2920106992403 2.99676561541091 1.06583755958398 5316 Uncharacterized conserved protein S conserved protein 250200 1.33470369163286 3.08708468136678 1.07033312518503 - - - conserved protein 250201 1.28517254770434 2.82270856572029 0.978748954990268 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S conserved protein 250202 1.30941189754791 2.80233137863658 0.926675847032022 640 Predicted transcriptional regulators K transcriptional regulator, ArsR family 250203 1.36586678402222 3.06908147713671 0.930418968725846 - - - hypothetical protein 250204 1.3045804301408 2.89416509162369 0.905630655911992 - - - conserved protein 250205 1.34040004534551 3.10286354090116 1.02047624480346 3118 Thioredoxin domain-containing protein O conserved protein 250206 1.29779170716193 3.32373098590683 1.13175046292349 785 Cytochrome c biogenesis protein O Cytochrome c-type biogenesis protein CcdA 250207 1.34336713060181 3.04446825749029 0.971035194645888 640 Predicted transcriptional regulators K transcriptional regulator, ArsR family 250208 1.36171865498407 3.13496022549593 1.02008773178465 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H putative methyltransferase 250209 1.39392306537162 3.17290757828062 1.03449286710396 394 Protein-tyrosine-phosphatase T arsenate reductase 250210 1.4278466935061 3.55118755675025 1.15805936866629 701 Predicted permeases R conserved protein 250211 1.45273204654052 3.28916586064135 1.04378092869061 640 Predicted transcriptional regulators K transcriptional regulator, ArsR family 250212 1.31404937298253 2.76757198236295 0.958411815993413 640 Predicted transcriptional regulators K conserved protein 250213 1.34118542730226 3.28703603160893 1.07449136759482 701 Predicted permeases R conserved protein 250214 1.25218444078931 2.75125714953369 0.897873837337307 - - - hypothetical protein 250215 1.28311680371712 2.91527025116823 1.00696057936261 - - - conserved protein 250216 1.2126158168154 2.86374673298476 1.02845139907691 4063 Tetrahydromethanopterin S-methyltransferase, subunit A H Tetrahydromethanopterin S-methyltransferase, subunit A 250217 1.25943090086772 2.91310598994441 1.00669016560523 - - - conserved protein 250218 1.31694906560788 3.10983259113867 1.09017078684878 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ Dihydropyrimidinase 250219 1.2216625131034 2.78936255624713 0.938818471423347 - - - conserved protein 250220 1.34266719538615 3.06851111431891 0.982803980914301 - - - conserved protein 250221 1.35402589456206 3.01002414026714 1.01788584910032 2230 Cyclopropane fatty acid synthase and related methyltransferases M conserved protein 250222 1.31536250346987 2.89416216743781 1.01875436917341 - - - conserved protein 250223 1.28915739211095 2.78078336404724 1.02302694817282 - - - conserved protein 250224 1.29169806445086 3.03836682838216 1.03205098733939 2923 Uncharacterized protein involved in the oxidation of intracellular sulfur P conserved protein 250225 1.34214137939686 3.09690173593419 1.0540870015537 1553 Uncharacterized conserved protein involved in intracellular sulfur reduction P hypothetical protein 250226 1.43066849839698 3.20088360682723 1.04363647194005 4871 Uncharacterized protein conserved in archaea S conserved protein 250227 1.34506170172923 3.03230782452052 1.02900277518779 4871 Uncharacterized protein conserved in archaea S conserved protein 250228 1.3458809881278 3.1816892145703 1.04838014963355 51 Ribosomal protein S10 J SSU ribosomal protein S10P 250229 1.28863621444049 2.92224738109821 0.887065270269855 5256 Translation elongation factor EF-1alpha (GTPase) J protein translation elongation factor 1A 250230 1.25820508177517 2.88983983780509 0.96381136485811 480 Translation elongation factors (GTPases) J protein translation elongation factor 2 250231 1.29495429902918 2.97512806494339 0.990006079255916 49 Ribosomal protein S7 J SSU ribosomal protein S7P 250232 1.33894259219744 3.04973722361129 1.00879838160024 48 Ribosomal protein S12 J SSU ribosomal protein S12P 250233 1.38123955206541 3.08762976594595 1.01512690715954 195 Transcription elongation factor K NusA protein homolog 250234 1.28170848178806 2.99287804000652 0.993760778906566 1911 Ribosomal protein L30E J LSU ribosomal protein L30E 250235 1.30750954023227 3.00446866349233 1.04414282294 86 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K DNA-directed RNA polymerase subunit A'' 250236 1.29019454734094 2.94993770372706 1.01344487489405 86 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K DNA-directed RNA polymerase subunit A' 250237 1.28118268706795 2.95314786958032 1.04204808542328 85 DNA-directed RNA polymerase, beta subunit/140 kD subunit K DNA-directed RNA polymerase beta chain 250238 1.28090979952144 2.87092168380014 1.00379668993499 85 DNA-directed RNA polymerase, beta subunit/140 kD subunit K DNA-directed RNA polymerase beta chain 250239 1.39457930384236 3.06268016314519 1.01793470558516 2012 DNA-directed RNA polymerase, subunit H, RpoH/RPB5 K DNA-directed RNA polymerase subunit H 250240 1.34646333167093 2.98515606706658 1.0516729198131 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250241 1.34478256272782 3.00319023587263 1.06861130991586 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250242 1.33569848906948 2.9302915940571 1.03943578958659 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250243 1.26142412027228 2.88179061290391 1.01778880369125 499 S-adenosylhomocysteine hydrolase H Adenosylhomocysteinase 250244 1.29405497959619 2.95123417848265 1.04661052737766 402 Cytosine deaminase and related metal-dependent hydrolases FR Chlorohydrolase family protein 250245 1.28468902229368 2.91146961026136 1.02235115146694 1418 Predicted HD superfamily hydrolase R conserved protein 250246 1.30492295237958 3.06460520950644 1.0725407557447 1701 Uncharacterized protein conserved in archaea S hypothetical protein 250247 1.26165046282454 2.97370669351233 1.01901753568123 1829 Predicted archaeal kinase (sugar kinase superfamily) R conserved protein 250248 1.34526426376546 3.14629033381572 1.10068208104935 452 Phosphopantothenoylcysteine synthetase/decarboxylase H DNA/pantothenate metabolism flavoprotein 250249 1.43172858911396 3.65751357177087 1.13685619069642 - - - conserved protein 250250 1.39390628162732 3.16860458848377 1.04226151548454 - - - conserved protein 250251 1.36197928962431 3.12187016519636 1.0625163944425 1503 Peptide chain release factor 1 (eRF1) J conserved protein 250252 1.32905574457715 3.22975876801029 1.07653078820059 3619 Predicted membrane protein S hypothetical protein 250253 1.29789412977774 2.92819754065792 1.03065624316137 293 23S rRNA methylase J methyltransferase 250254 1.34072327176825 3.0617262081107 1.03760579604041 1387 Histidinol phosphatase and related hydrolases of the PHP family ER hypothetical protein 250255 1.45285056176686 3.47326001913828 1.04907400828001 860 N-acetylmuramoyl-L-alanine amidase M Cell surface protein 250256 1.45734834417782 3.21205346892548 1.0592645490611 1451 Predicted metal-dependent hydrolase R Zinc metalloprotease 250257 1.35528359482463 3.01588395381386 1.0198083485032 610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V type I restriction-modification system restriction subunit 250258 1.45017662275351 3.37150561702705 1.08676539820694 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 250259 1.37100537509235 3.0470922548549 1.01716549178111 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system specificity subunit 250260 1.29598655718044 3.13579147379068 1.08257268560264 3291 FOG: PKD repeat R surface layer protein B 250261 1.31583826928356 3.20017340698758 1.05097330676129 - - - conserved protein 250262 1.32028945107077 3.1660386405232 1.10218942574263 - - - conserved protein 250263 1.28332927023832 2.97252062997173 1.06511668337635 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU conserved protein 250264 1.25846547184009 2.94041284486281 1.03268273384492 4069 Uncharacterized protein conserved in archaea S hypothetical protein 250265 1.27429345113356 3.00736632796517 1.0560748677423 2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold R metal dependent hydrolase 250266 1.31807878082627 3.04023341624879 1.06038527022731 1151 6Fe-6S prismane cluster-containing protein C Carbon monoxide dehydrogenase 250267 1.2868892320417 2.96450737960771 1.05874926163975 3875 Uncharacterized conserved protein S conserved protein 250268 1.28344819001173 2.92598636762991 1.03969981092757 3875 Uncharacterized conserved protein S transcriptional regulator 250269 1.46862080292894 3.30169712053291 0.97954379858167 1943 Transposase and inactivated derivatives L Transposase 250270 1.30910951114318 3.2370739807037 1.13147662723167 591 Na+/proline symporter ER sodium/proline symporter 250271 1.2740454422326 3.00155848079007 1.05969948759019 252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D EJ L-asparaginase 250272 1.29721185548668 3.03317971196729 1.06774938444751 165 Argininosuccinate lyase E Argininosuccinate lyase 250273 1.30023208492004 2.98722060267013 1.03307340874649 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H methyltransferase 250274 1.27607599614874 3.14321379384473 1.09164895982927 3366 Uncharacterized protein conserved in archaea S hypothetical protein 250275 1.29280026733904 2.88628540277451 1.00414358794448 661 Predicted unusual protein kinase R ubiquinone biosynthesis protein 250276 1.21539290461894 2.65678323139285 1.06305083487427 - - - COP associated protein 250277 1.31781737617686 3.03709935287607 1.0505366126924 2864 Cytochrome b subunit of formate dehydrogenase C F420-nonreducing hydrogenase I, cytochrome B subunit 250278 1.24262528334435 2.95605770984298 0.991772575065893 374 Ni,Fe-hydrogenase I large subunit C F420-nonreducing hydrogenase I, large subunit 250279 1.32732776627512 3.0701048339984 1.00999606058655 1740 Ni,Fe-hydrogenase I small subunit C F420-nonreducing hydrogenase I precursor 250280 1.30669828566333 3.00565967196306 1.01649195834406 298 Hydrogenase maturation factor O Hydrogenase expression/formation protein 250281 1.30543160826725 3.02918797514148 1.02896640729754 409 Hydrogenase maturation factor O Hydrogenase expression/formation protein 250282 1.29411523499691 2.8553701544433 0.967116664948318 375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) R Hydrogenase expression/formation protein 250283 1.27853926006666 2.95590659697699 1.03275431481335 378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase OK Hydrogenase expression/formation protein 250284 1.28154896448698 3.06008088965128 1.07512841594161 309 Hydrogenase maturation factor O Hydrogenase expression/formation protein 250285 1.33324070488797 3.28401720150422 1.11166340196554 1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit CP Ech Hydrogenase, Subunit 250286 1.40385293276783 3.50911455074942 1.14532107678827 650 Formate hydrogenlyase subunit 4 C Ech Hydrogenase, Subunit 250287 1.32184254482146 3.0833895328199 1.03185513191259 3260 Ni,Fe-hydrogenase III small subunit C Ech Hydrogenase, Subunit 250288 1.5589012486928 3.4014674961866 1.05318259028642 - - - Ech Hydrogenase, Subunit 250289 1.29175076487053 2.99632952172803 0.991263923331948 3261 Ni,Fe-hydrogenase III large subunit C Ech Hydrogenase, Subunit 250290 1.41248722539813 3.18748383144277 0.980854928089186 1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) C Ech Hydrogenase, Subunit 250291 1.34918381373228 2.90089170401696 0.994705211146574 2608 Copper chaperone P COP associated protein 250292 1.31128911107416 3.17797423375028 1.12605986886775 2608 Copper chaperone P COP associated protein 250293 1.28437203336547 3.03696518325888 1.08046649778413 2217 Cation transport ATPase P Copper-exporting ATPase 250294 1.37340306100514 3.45552392192381 1.12194463406545 - - - conserved protein 250295 1.27755823829448 3.02241388532276 1.07983402196341 4895 Uncharacterized conserved protein S hypothetical protein 250296 1.31094691789806 3.19216780069807 1.09794813355556 2270 Permeases of the major facilitator superfamily R Uncharacterized permease 250297 1.27889530532999 2.91189175075317 0.984416536387654 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H SAM-dependent methyltransferases 250298 1.2896093048699 3.21643980541311 1.09690680883377 2076 Membrane transporters of cations and cationic drugs P Multidrug efflux pump 250299 1.56177954447272 3.74751790131073 1.09931632502679 - - - conserved protein 250300 1.52737017662546 3.68932182075982 1.11774568996916 - - - conserved protein 250301 1.34006076909084 3.09882581862796 1.08135318070866 361 Translation initiation factor 1 (IF-1) J translation initiation factor 1A 250302 1.45806848427221 3.34900280333131 1.08976867577783 - - - conserved protein 250303 1.30284044279634 3.00547834995472 1.02532630271834 - - - DNA-directed RNA polymerases I, II, and III, 7.3 kDa polypeptide 250304 1.22397482674651 2.73176968925643 1.003284585049 361 Translation initiation factor 1 (IF-1) J translation initiation factor 1A 250305 1.29119297714362 2.96779731778921 1.02683201008521 28 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome) EH Acetolactate synthase 250306 1.2972388615656 2.96689157343646 1.03671850348057 1012 NAD-dependent aldehyde dehydrogenases C Succinate-semialdehyde dehydrogenase [NADP+] 250307 1.33154755520282 3.0482074198153 0.969975997356205 - - - hypothetical protein 250308 1.35258832877604 3.16117564900556 1.03104130909811 3794 Plastocyanin C Copper-binding protein 250309 1.28822992997632 3.10408568243346 1.07206693453878 3794 Plastocyanin C Copper-binding protein 250310 1.34531606636587 2.89780490721696 0.948311104067433 3666 Transposase and inactivated derivatives L Transposase 250311 1.29422875127891 2.94842660781165 1.01488641921761 2242 Precorrin-6B methylase 2 H methyltransferase 250312 1.2914152406609 3.00498847871645 1.04028153146415 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ Ribosomal protein S6 modification protein 250313 1.24125680234601 2.66439139573356 0.930360479804869 3063 Tfp pilus assembly protein PilF NU O-linked N-acetylglucosamine transferase 250314 1.26027957986429 2.7235404129609 0.912421889355581 1011 Predicted hydrolase (HAD superfamily) R putative phosphatase 250315 1.25061012043721 2.70677633564478 0.947555358535136 3063 Tfp pilus assembly protein PilF NU O-linked N-acetylglucosamine transferase 250316 1.30443454051068 2.96868856959742 1.00334232271503 3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain T transcriptional regulator 250317 1.33591858899247 3.0601229729459 1.07064907283983 - - - conserved protein 250318 1.30358544426266 3.06170447104331 1.05367126409091 492 Thioredoxin reductase O Thioredoxin reductase 250319 1.39528676308041 3.16920257646258 0.985866340295852 - - - Thioredoxin 250320 1.3084798431316 3.02355348084228 1.01012288248177 1798 Diphthamide biosynthesis methyltransferase J Diphthine synthase 250321 1.32375644754296 2.89074105915937 0.975868519292414 1849 Uncharacterized protein conserved in archaea S conserved protein 250322 1.32559116288854 3.03891180774426 0.986415264688424 1885 Uncharacterized protein conserved in archaea S hypothetical protein 250323 1.22643802268487 2.88462715277376 1.02058267722207 524 Sugar kinases, ribokinase family G 6-phosphofructokinase 250324 1.27649664588548 2.95976232641562 1.04572196118902 2102 Predicted ATPases of PP-loop superfamily R conserved protein 250325 1.30685495698034 3.27592281345232 1.12020256290287 41 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase F Phosphoribosylaminoimidazole carboxylase, catalytic subunit 250326 1.30765398102469 3.02378865838413 1.08197631022882 1605 Chorismate mutase E chorismate mutase 250327 1.32323329249869 3.19383690612799 1.07385256612294 1685 Archaeal shikimate kinase EH Shikimate kinase 250328 1.33731354987247 3.10389097370698 1.07090195981905 704 Phosphate uptake regulator P conserved protein 250329 1.24338700194463 2.88083233541045 1.00912688506002 1100 GTPase SAR1 and related small G proteins R GTP-binding protein 250330 1.31217058474212 3.01701245615887 1.04229340198563 3365 Uncharacterized protein conserved in archaea S conserved protein 250331 1.38533084247926 3.09211737378751 0.980542299743494 - - - conserved protein 250332 1.28364793952771 3.03662734075911 1.04917523081144 794 Predicted sugar phosphate isomerase involved in capsule formation M hexulose-6-phosphate isomerase 250333 1.27800327912604 3.0125291285017 1.06645749382167 436 Aspartate/tyrosine/aromatic aminotransferase E Aspartate aminotransferase 250334 1.35689569857592 3.35812256932125 1.1229983861943 785 Cytochrome c biogenesis protein O Cytochrome c-type biogenesis protein 250335 1.31743680054418 3.03989523375055 1.06095432134912 1084 Predicted GTPase R GTP-binding protein 250336 1.28564473903588 2.95145586867543 1.01434930679961 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K conserved protein 250337 1.33543952593692 3.01825098479715 0.992954750250454 140 Phosphoribosyl-ATP pyrophosphohydrolase E Phosphoribosyl-ATP pyrophosphatase 250338 1.33308658121683 3.09391268171143 1.0666019117648 65 3-isopropylmalate dehydratase large subunit E 3-isopropylmalate dehydratase 250339 1.20814806939203 2.66824888105266 0.94818173062219 727 Predicted Fe-S-cluster oxidoreductase R conserved protein 250340 1.30906003034525 3.10513732046791 1.06348936096287 2150 Predicted regulator of amino acid metabolism, contains ACT domain R conserved protein 250341 1.37843616820847 3.17834400322139 1.07119773915802 - - - conserved protein 250342 1.25916240026435 2.9348652965321 1.00514241264382 1714 Predicted membrane protein/domain S hypothetical protein 250343 1.28532211027197 3.06462012079624 1.06134573433437 2237 Predicted membrane protein S Conserved transmembrane protein 250344 1.24125549535884 2.89774740479424 1.0143004604764 5 Purine nucleoside phosphorylase F 5'-methylthioadenosine phosphorylase 250345 1.25281747307754 2.86743114289526 1.00232773674567 1202 Superfamily II helicase, archaea-specific R ATP-dependent DNA helicase 250346 1.297185182608 2.97046508254751 1.01828438044861 - - - conserved protein 250347 1.4230619005182 3.32700485723118 1.0261072656231 - - - hypothetical protein 250348 1.29571770691414 3.05533737369086 1.02993108978216 1958 Small nuclear ribonucleoprotein (snRNP) homolog K Small nuclear riboprotein-like protein 250349 1.24008566562785 2.6370425744205 0.94763459135382 - - - conserved protein 250350 1.30576358439721 3.01209870009902 1.04356819362291 - - - conserved protein 250351 1.27940232928517 3.29704379362289 1.11791539575262 - - - hypothetical protein 250352 1.30725941713887 2.98565204550821 1.05065316412628 1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase R Cobalt transport ATP-binding protein 250353 1.28510805023842 3.19567761469172 1.06158321483585 619 ABC-type cobalt transport system, permease component CbiQ and related transporters P Cobalt transport protein 250354 1.29472435869603 3.15293035560298 1.09867198088917 823 Periplasmic component of the Tol biopolymer transport system U conserved protein 250355 1.39762324007251 3.11519864489105 1.01878709309068 3328 Transposase and inactivated derivatives L Transposase 250356 1.27292672688055 2.68507649140503 0.914823915621868 - - - hypothetical protein 250357 1.27629497020255 2.89698765996887 1.01349189803762 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ Long-chain-fatty-acid--CoA ligase 250358 1.28851846782659 3.10521347881708 1.07253826849163 824 Predicted thioesterase R conserved protein 250359 1.37401812132385 3.25386818789741 1.10850112828224 1476 Predicted transcriptional regulators K transcriptional regulator, MerR family 250360 1.2689283903791 2.94964887165832 1.01578533938317 1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family C NADH:flavin oxidoreductases 250361 1.31809131319729 3.20570747800076 1.11259472116309 755 ABC-type transport system involved in cytochrome c biogenesis, permease component O Heme exporter, protein C 250362 1.30552639626733 3.23594666358989 1.08440450624734 2386 ABC-type transport system involved in cytochrome c biogenesis, permease component O Heme exporter, protein B 250363 1.25503842668961 2.95409012061543 1.03651229712603 1131 ABC-type multidrug transport system, ATPase component V ABC transporter, ATP-binding protein 250364 1.25464059425051 2.70938017843434 0.961593133739617 225 Peptide methionine sulfoxide reductase O Peptide methionine sulfoxide reductase 250365 1.27200789352213 2.91522340148874 1.00953534713403 1881 Phospholipid-binding protein R hypothetical protein 250366 1.30821307446892 2.88658884494432 1.05098127575065 - - - conserved protein 250367 1.34563452700246 3.16402975050501 1.07599213192572 2006 Uncharacterized conserved protein S hypothetical protein 250368 1.3474160018633 3.10006852776557 1.08772391802658 3273 Uncharacterized conserved protein S Potassium channel protein 250369 1.2387870945263 3.24305287555218 1.13683006438296 1824 Permease, similar to cation transporters P Cation transporter 250370 1.33957840955051 3.43963094989528 1.1645479832345 1824 Permease, similar to cation transporters P Cation transporter 250371 1.31741261246867 3.05960652458314 0.88603060575973 - - - conserved protein 250372 1.32185042934635 3.14138499053566 1.05199171293361 - - - conserved protein 250373 1.446629316877 3.5772009961728 1.10976158998545 - - - conserved protein 250374 1.37515600723761 3.10369648207774 0.92507927185195 - - - conserved protein 250375 1.3426623826509 2.875628058285 0.956143916997162 - - - conserved protein 250376 1.4253067230762 3.37278416764485 1.03230273381737 1662 Transposase and inactivated derivatives, IS1 family L hypothetical protein 250377 1.43047678821062 3.16485357691064 0.967543793698787 - - - conserved protein 250378 1.31915286445109 2.91841492759453 0.943665308418982 - - - conserved protein 250379 1.45645813454338 3.50797255472041 1.0022354094413 - - - hypothetical protein 250380 1.45158515585137 3.05098877526639 0.971218833008334 - - - hypothetical protein 250381 1.29973580787176 2.9993300817282 1.06297202187559 - - - transcriptional regulatory protein, AsnC family 250382 1.30835447643644 2.97207219328111 1.03425221403737 1389 DNA topoisomerase VI, subunit B L Type II DNA topoisomerase VI, subunit B 250383 1.33161386584317 2.94437584207657 1.02746323919903 1697 DNA topoisomerase VI, subunit A L Type II DNA topoisomerase VI, subunit A 250384 1.33290793542578 3.02173480775576 1.05890231131083 187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit L DNA gyrase, subunit B 250385 1.28333795376557 2.89983759444304 1.0094788755584 188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit L DNA gyrase, subunit A 250386 1.41900318940278 3.1520344624798 0.953344197453238 326 Molecular chaperone, HSP90 family O Chaperone protein 250387 1.28137602711955 3.0648996922957 1.04395863947519 1988 Predicted membrane-bound metal-dependent hydrolases R conserved protein 250388 1.24133573519136 2.6660624285286 0.95217573671779 605 Superoxide dismutase P Superoxide dismutase 250389 1.30482917308515 3.0932238929989 1.08547448007975 1988 Predicted membrane-bound metal-dependent hydrolases R conserved protein 250390 1.2326651331379 2.91648118965751 1.00913180221865 1988 Predicted membrane-bound metal-dependent hydrolases R conserved protein 250391 1.27642556936199 2.92077820920377 0.988882187169906 412 Dienelactone hydrolase and related enzymes Q Dienelactone hydrolase 250392 1.30756500113084 3.05032381207537 1.04946524272369 407 Uroporphyrinogen-III decarboxylase H Methylthiol:coenzyme M methyltransferase 250393 1.24726735605771 2.83460496594556 0.963010239566112 5012 Predicted cobalamin binding protein R Methylthiol:coenzyme M methyltransferase 250394 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 250395 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 250396 1.35072566386488 3.248914877275 1.12592255901269 671 Membrane-associated phospholipid phosphatase I conserved protein 250397 1.24529105436571 2.80208306350857 0.940735297643867 214 Pyridoxine biosynthesis enzyme H putative pyridoxine biosynthesis protein 250398 1.35917895389179 3.13277964009069 1.05286589017109 311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis H Imidazoleglycerol-phosphate synthase 250399 1.44736729673257 3.15691424660245 0.963548400853079 - - - conserved protein 250400 1.40257305951514 3.10106446302876 1.0498157263524 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250401 1.35027523300376 2.85527078332441 0.904425034198443 3436 Transposase and inactivated derivatives L Transposase 250402 1.4870876986477 3.43697792061466 0.964986698842284 - - - Transposase 250403 1.31085088950258 2.77430433721293 0.981612103066229 3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase R hypothetical protein 250404 1.46862080292894 3.30169712053291 0.97954379858167 1943 Transposase and inactivated derivatives L Transposase 250405 1.26786260666071 3.09873537083326 1.04092008661411 - - - conserved protein 250406 1.35022703165043 3.12758587254207 1.03711655033873 3398 Uncharacterized protein conserved in archaea S transcriptional regulator, ArsR family 250407 1.3600334056639 3.21536797494572 0.947816876986422 - - - conserved protein 250408 1.36407892358168 3.16710971363986 0.926903583902528 2834 Outer membrane lipoprotein-sorting protein M conserved protein 250409 1.37139166325907 3.18959680668498 0.985463380328835 - - - conserved protein 250410 1.41173113416826 3.41720940697877 1.08956047307535 785 Cytochrome c biogenesis protein O conserved protein 250411 1.34842665118166 3.03692380289001 1.00281603478959 3398 Uncharacterized protein conserved in archaea S transcriptional regulator, ArsR family 250412 1.44665099413462 3.13836288946848 1.02417523085174 - - - Transposase 250413 1.27417292684946 2.69086059812037 0.89964146870119 - - - Transposase 250414 1.38833191240426 3.10788497199032 0.922950548043234 - - - conserved protein 250415 1.39762324007251 3.11519864489105 1.01878709309068 3328 Transposase and inactivated derivatives L Transposase 250416 1.32224363347819 3.08640290009294 0.922653683515401 - - - conserved protein 250417 1.39319844484761 3.31097044846365 1.03401266769093 785 Cytochrome c biogenesis protein O conserved protein 250418 1.41117734769115 3.52529626120883 1.06693994296882 2881 Uncharacterized protein conserved in archaea S conserved protein 250419 1.37544549114862 3.45579246874648 1.16995942399209 1682 ABC-type polysaccharide/polyol phosphate export systems, permease component GM ABC transporter, permease protein 250420 1.36509709647886 3.23155659937364 1.08893961660731 1131 ABC-type multidrug transport system, ATPase component V ABC transporter, ATP-binding protein 250421 1.26538514771839 3.05452704119309 1.07613606956445 1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase R Dipeptide/oligopeptide transporter, ATP-binding protein 250422 1.33406835234363 3.24018527850565 1.1017077159473 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Dipeptide/oligopeptide transporter, permease protein 250423 1.30387786040323 3.22526097250902 1.10992599294959 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Dipeptide/oligopeptide transporter, permease protein 250424 1.31814613462705 2.9859319084953 1.03145782389113 2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase H methyltransferase 250425 1.30195094721726 3.0235553808003 1.06042591042856 747 ABC-type dipeptide transport system, periplasmic component E Dipeptide/oligopeptide-binding protein 250426 1.41871318924238 3.54648878729085 1.13314426847435 - - - conserved protein 250427 1.28829986237196 2.970362632119 1.01427689961897 2125 Ribosomal protein S6E (S10) J SSU ribosomal protein S6E 250428 1.29446997936303 2.98008956373094 1.03190936804298 532 Translation initiation factor 2 (IF-2; GTPase) J protein translation initiation factor IF2 250429 1.32284512372573 3.13994211599587 1.04785670464855 105 Nucleoside diphosphate kinase F Nucleoside diphosphate kinase 250430 1.2726082057401 2.72431311776335 1.01291500999399 2075 Ribosomal protein L24E J LSU ribosomal protein L24E 250431 1.28567691510967 3.0350624657634 1.02260292411128 2053 Ribosomal protein S28E/S33 J SSU ribosomal protein S28E 250432 1.22224546197521 2.66209595497121 0.941815762300486 1358 Ribosomal protein HS6-type (S12/L30/L7a) J LSU ribosomal protein L7AE 250433 1.29732855500965 2.99922618031074 1.02358087348394 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 250434 1.30277293442076 3.16465681213153 1.09860565738121 1520 FOG: WD40-like repeat S hypothetical protein 250435 1.2909812789828 3.2749992452095 1.13004228836003 3391 Uncharacterized conserved protein S putative surface layer protein 250436 1.22440966242982 2.93334929587806 1.03657087202843 3420 Nitrous oxidase accessory protein P hypothetical protein 250437 1.28736370760959 2.90893916034865 0.979875818565681 1708 Predicted nucleotidyltransferases R nucleotidyltransferase 250438 1.30159490234976 2.9340552602775 0.996634538253483 2445 Uncharacterized conserved protein S hypothetical protein 250439 1.31098265838246 2.85283771789176 0.924989334137305 1670 Acetyltransferases, including N-acetylases of ribosomal proteins J Ribosomal-protein-alanine acetyltransferase 250440 1.36696953493873 3.17310213546506 1.03274894805972 1753 Uncharacterized conserved protein S hypothetical protein 250441 1.28625084618264 2.80318268373734 0.970597611325603 1670 Acetyltransferases, including N-acetylases of ribosomal proteins J Ribosomal-protein-alanine acetyltransferase 250442 1.32067787673118 3.3086161548018 0.978337904149026 - - - hypothetical protein 250443 1.34596380236114 3.24058533099535 1.07710965772813 2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R putative chloride channel 250444 1.22924492172657 2.7361376334595 0.919313983405221 - - - F420H2 dehydrogenase subunit 250445 1.29234585838844 3.15274832720604 1.07254956076189 1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N) C F420H2 dehydrogenase subunit 250446 1.3247363556484 3.2606299700296 1.11939045684066 1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M) C F420H2 dehydrogenase subunit 250447 1.29726245029774 3.18141151956959 1.09947198081577 1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit CP F420H2 dehydrogenase subunit 250448 1.38224633818384 3.33150150477149 1.1286379333451 713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) C F420H2 dehydrogenase subunit 250449 1.37066197808527 3.38402291391879 1.12428297948032 839 NADH:ubiquinone oxidoreductase subunit 6 (chain J) C F420H2 dehydrogenase subunit 250450 1.30483809174563 3.2035904358389 1.04763251026544 839 NADH:ubiquinone oxidoreductase subunit 6 (chain J) C F420H2 dehydrogenase subunit 250451 1.36388274772679 3.08361135677244 0.994157931022029 1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) C F420H2 dehydrogenase subunit 250452 1.30212439093247 3.17481474277583 1.12179364331639 1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H) C F420H2 dehydrogenase subunit 250453 1.2336163280939 2.83973877703852 0.976802798701494 649 NADH:ubiquinone oxidoreductase 49 kD subunit 7 C F420H2 dehydrogenase subunit 250454 1.29814590818643 2.94377462428868 1.04090395796296 852 NADH:ubiquinone oxidoreductase 27 kD subunit C F420H2 dehydrogenase subunit 250455 1.32691189578208 2.98189558235281 1.01177254142398 377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases C F420H2 dehydrogenase subunit 250456 1.29521596600139 3.12841256641418 1.04519925248643 838 NADH:ubiquinone oxidoreductase subunit 3 (chain A) C F420H2 dehydrogenase subunit 250457 1.31879547135799 2.89334097563388 1.05758503940678 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C putative ferredoxin 250458 1.26761574490569 2.9856572530358 1.05576218292123 1233 Phytoene dehydrogenase and related proteins Q putative oxidoreductase 250459 1.31353407808272 3.00983026397072 1.0395203294042 1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes HR Biotin synthase 250460 1.2990272764411 2.97115637182489 1.03947496401584 1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes HR Biotin synthase 250461 1.27474190130443 2.91504478176106 1.02091259867625 1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes HR Biotin synthase 250462 1.34115392158846 3.095062316951 1.04124007302341 1920 Uncharacterized conserved protein S hypothetical protein 250463 1.33181258386996 2.86676066749005 0.949787914552966 - - - conserved protein 250464 1.29305502240843 2.94616676787974 1.03239466618607 644 Dehydrogenases (flavoproteins) C Geranylgeranyl reductase 250465 1.31801082062711 3.27120688368582 1.14656705947255 168 Trk-type K+ transport systems, membrane components P Trk system potassium uptake protein 250466 1.29754498268898 2.98905575716736 1.04926391767796 569 K+ transport systems, NAD-binding component P Trk system potassium uptake protein 250467 1.32824901899215 3.23874827823285 1.11095128688268 168 Trk-type K+ transport systems, membrane components P Trk system potassium uptake protein 250468 1.27965827780342 2.98266903585959 1.05092535579439 569 K+ transport systems, NAD-binding component P Trk system potassium uptake protein 250469 1.30064948343304 2.96796026448061 1.04603646982927 484 DnaJ-class molecular chaperone with C-terminal Zn finger domain O Chaperone protein 250470 1.2595977323133 2.8447977391946 0.97466976201748 443 Molecular chaperone O Chaperone protein 250471 1.31726246445842 2.83472822491044 0.98627984631241 576 Molecular chaperone GrpE (heat shock protein) O GrpE protein 250472 1.29140190534604 2.9722446919453 0.919696000775137 - - - Transposase 250473 1.36384103630324 3.38380475463545 1.12322177863454 - - - Heat shock protein 250474 1.29140190534604 2.9722446919453 0.919696000775137 - - - Transposase 250475 1.35078584440611 3.13646226256593 1.08855173201986 1821 Predicted ATP-utilizing enzyme (ATP-grasp superfamily) R hypothetical protein 250476 1.34148609863858 3.08836318372618 1.05788720514219 1548 Predicted transcriptional regulator/sugar kinase KG hypothetical protein 250477 1.32941097632443 3.07870140905177 1.05765537358713 2054 Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases R 1-pyrroline-5-carboxylate synthetase 250478 1.29079202465873 2.8413443851396 1.06056747056892 2888 Predicted Zn-ribbon RNA-binding protein with a function in translation J hypothetical protein 250479 1.26881510770139 2.87172631227077 1.03579776326462 2092 Translation elongation factor EF-1beta J Archaeal protein translation elongation factor 1, subunit beta 250480 1.291866040536 2.81380405152763 0.98945021876234 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250481 1.32307922876081 2.90057518431663 1.01694041408296 784 FOG: CheY-like receiver T putative transcriptional regulator 250482 1.30774941814253 3.03958211589178 1.05324468654162 301 Thiamine biosynthesis ATP pyrophosphatase H Thiamine biosynthesis protein 250483 1.30216134597685 2.94074454154723 1.0374561224892 642 Signal transduction histidine kinase T Sensory transduction histidine kinases 250484 1.26731603100676 2.99792758890575 1.07672839241604 1161 Predicted GTPases R GTP-binding protein homolog 250485 1.32289778136784 3.07893301698701 1.01394051365146 - - - conserved protein 250486 1.31290752705134 3.12894713139902 0.957626199569556 - - - hypothetical protein 250487 1.25176842772244 2.97780034324949 1.06658536281829 589 Universal stress protein UspA and related nucleotide-binding proteins T Universal stress protein 250488 1.21318549112012 2.64988683117103 0.956685045720954 - - - hypothetical protein 250489 1.34247025184992 2.87452195929422 1.00325701431951 1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription KT Phage shock protein A 250490 1.26710011009648 2.85962526861745 0.998930452768013 1719 Predicted hydrocarbon binding protein (contains V4R domain) R hypothetical protein 250491 1.27419889447495 2.88834507165983 1.02331914519343 4044 Uncharacterized protein conserved in archaea S conserved protein 250492 1.3093733617567 2.870704906921 0.987635481536073 - - - hypothetical protein 250493 1.33688091703699 3.10589815978379 1.0631414520817 1867 N2,N2-dimethylguanosine tRNA methyltransferase J N2,N2-dimethylguanosine tRNA methyltransferase 250494 1.3666131672758 3.12974770660381 1.03304829329629 - - - hypothetical protein 250495 1.39762324007251 3.11519864489105 1.01878709309068 3328 Transposase and inactivated derivatives L Transposase 250496 1.22960015599224 2.85164300786501 1.01712972611659 - - - hypothetical protein 250497 1.30396796099571 3.25694135027018 1.12683640831483 3174 Predicted membrane protein S hypothetical protein 250498 1.25702315908061 2.81608499501089 0.95690930699736 2129 Predicted phosphoesterases, related to the Icc protein R hypothetical protein 250499 1.30806986760524 3.08657362645039 1.04358597989581 1901 Uncharacterized conserved protein S Conserved hypothetical protein 250500 1.3293947070456 2.98722345651561 1.04240400121642 1258 Predicted pseudouridylate synthase J Conserved hypothetical protein 250501 1.23006740647693 2.73834202491281 0.970043986534499 2139 Ribosomal protein L21E J LSU ribosomal protein L21E 250502 1.39999780932121 3.10672651479087 1.06052140162198 1460 Uncharacterized protein conserved in archaea S hypothetical protein 250503 1.29955488778408 2.94954898718461 1.0488716288375 1491 Predicted RNA-binding protein J Conserved hypothetical protein 250504 1.35630074241004 3.11705126008224 1.06164545667745 30 Dimethyladenosine transferase (rRNA methylation) J Dimethyladenosine transferase 250505 1.36825970039827 3.22349096711471 1.07363099007336 2890 Methylase of polypeptide chain release factors J Conserved hypothetical protein 250506 1.31027301212211 3.11333306680691 1.08245303885737 474 Cation transport ATPase P Cation-transporting ATPase 250507 1.26524280524659 2.85800726696372 1.01087161590361 2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding L phosphohydrolase 250508 1.48381368171032 3.35226316303119 0.938483685132306 - - - hypothetical protein 250509 1.3169100635265 2.96658271993898 0.98987088917344 - - - hypothetical protein 250510 1.32454082105645 3.05052798116711 1.00385007767107 - - - hypothetical protein 250511 1.41351576340223 3.09027194091033 0.997119253323325 1309 Transcriptional regulator K Conserved hypothetical protein 250512 1.36588146354826 3.16094756323718 1.02394331244409 1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain C putative ferredoxin 250513 1.37395052341517 3.32600261911119 0.959280045958367 - - - hypothetical protein 250514 1.38217697861109 2.92341352126226 0.90842567742449 - - - Conserved hypothetical protein 250515 1.53176496784865 3.15475688943869 0.953199705443726 - - - hypothetical protein 250516 1.33280166276988 2.84547528047061 0.91787958998694 4845 Chloramphenicol O-acetyltransferase V Acetyltransferase 250517 1.38081614716868 3.20818810815902 1.04312542433152 1357 Uncharacterized low-complexity proteins S hypothetical protein 250518 1.34576212089857 3.13420146959199 1.03887637834864 596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R putative hydrolase 250519 1.37958975383238 2.97141717519826 0.920026863954535 3153 Predicted acetyltransferase R Acetyltransferase 250520 1.52620451325338 3.46954113351882 1.04747023252515 - - - hypothetical protein 250521 1.36950066812807 3.14287952665554 1.06572621768655 513 Superfamily II DNA and RNA helicases LKJ ATP-dependent RNA helicase 250522 1.34225845968516 2.98879600287378 1.02340656218726 753 Catalase P Catalase 250523 1.47042158953103 3.21516083615963 0.925832042009366 - - - hypothetical protein 250524 1.43362046629591 3.16063189412203 0.966949623519393 - - - hypothetical protein 250525 1.43334028297102 3.18467161218519 0.881308043832613 - - - hypothetical protein 250526 1.30233643338856 3.06609765399421 1.0671979309784 1162 Predicted GTPases R Conserved hypothetical protein 250527 1.30547810629749 2.78892762697252 0.989408461848454 - - - hypothetical protein 250528 1.28035708153665 2.90574676387581 1.00377770243626 2768 Uncharacterized Fe-S center protein R Ferredoxin 250529 1.27034118871861 2.81492581028234 0.964234773521694 1504 Uncharacterized conserved protein S hypothetical protein 250530 1.26274335313531 2.86527807630435 0.988737025202985 1180 Pyruvate-formate lyase-activating enzyme O Pyruvate formate-lyase activating enzyme 250531 1.32043651878012 2.99754662798236 1.0112048935951 3640 CO dehydrogenase maturation factor D CODH nickel-insertion accessory protein 250532 1.28375362754018 2.97495891079704 1.03556037200207 747 ABC-type dipeptide transport system, periplasmic component E ABC transporter, periplasmic binding protein 250533 1.36242940042818 3.36921115035071 1.11784454360458 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP ABC transporter, permease protein 250534 1.3530691268096 3.29034356304992 1.1319152954326 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP ABC transporter, permease protein 250535 1.32608277285746 3.07270835175925 1.07302097052929 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP ABC transporter, ATP-binding protein 250536 1.35854779389929 3.17462333890755 1.05758053720489 4608 ABC-type oligopeptide transport system, ATPase component E ABC transporter, ATP-binding protein 250537 1.25881286392595 2.8691320930973 1.0048146437457 - - - methyltransferase 250538 1.26407409317859 2.67833249241245 0.95263796293688 1321 Mn-dependent transcriptional regulator K hypothetical protein 250539 1.35373744456029 3.17672809317666 1.01168474938134 - - - conserved protein 250540 1.27428024500306 3.14542131042644 1.07491278345223 - - - hypothetical protein 250541 1.31676737259706 3.15078927071239 1.10999519314612 370 Fe2+ transport system protein B P Ferrous iron transport protein B 250542 1.43930429724819 3.41915484400466 1.1300317530789 1918 Fe2+ transport system protein A P hypothetical protein 250543 1.39045629623463 3.22529075474035 1.06286112121886 1918 Fe2+ transport system protein A P Ferrous iron transport protein A 250544 1.35538773978052 3.0725204048025 0.92451933888601 3547 Transposase and inactivated derivatives L Transposase 250545 1.42125000024269 3.18473204686465 0.982683114420869 - - - hypothetical protein 250546 1.31475457398971 2.95789489965035 1.04002096095946 1180 Pyruvate-formate lyase-activating enzyme O Pyruvate formate-lyase activating enzyme-like protein 250547 1.31828001250142 2.96038065269304 1.02576071692348 1443 Isopentenyldiphosphate isomerase I hypothetical protein 250548 1.26046150309469 2.77453692789341 0.984071440106169 1826 Sec-independent protein secretion pathway components U Sec-independent protein translocase, protein 250549 1.30969039327633 2.74987402583254 1.00759237202032 1826 Sec-independent protein secretion pathway components U Sec-independent protein translocase, protein 250550 1.33756155828617 3.24959869148458 1.10783451621052 805 Sec-independent protein secretion pathway component TatC U Sec-independent protein translocase, protein 250551 1.29837245487312 3.26286273860552 1.13609820651001 805 Sec-independent protein secretion pathway component TatC U Sec-independent protein translocase, protein 250552 1.26254968282215 3.11930066973414 1.08088798253896 3391 Uncharacterized conserved protein S putative surface layer protein 250553 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 250554 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 250555 1.44038299326245 3.15414815631787 1.0321743185305 - - - Transposase 250556 1.28756332805646 3.29290345396043 1.1164205135566 - - - hypothetical protein 250557 1.28054425869062 2.90108871292107 1.0409957805445 1112 Superfamily I DNA and RNA helicases and helicase subunits L hypothetical protein 250558 1.36114892371845 3.41435006271431 1.16070058990315 2962 Predicted permeases R hypothetical protein 250559 1.36503914185454 2.99396750478547 1.03197888709774 4783 Putative Zn-dependent protease, contains TPR repeats R hypothetical protein 250560 1.3089844316613 2.96125314857738 1.03256781427882 1945 Uncharacterized conserved protein S hypothetical protein 250561 1.28008258488034 3.02898035878009 1.07557088639229 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ hypothetical protein 250562 1.30455103461686 3.05817926252055 1.04885604109349 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ hypothetical protein 250563 1.27964013969287 3.03224587236594 1.05540456578161 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ hypothetical protein 250564 1.38508626362174 2.8669471349606 0.990134233493783 - - - hypothetical protein 250565 1.2841641298305 3.01716830434695 1.01473217843968 2026 Cytotoxic translational repressor of toxin-antitoxin stability system JD conserved protein 250566 1.33943510689197 2.92301170770714 1.00344742031194 1451 Predicted metal-dependent hydrolase R Zinc metalloprotease 250567 1.18673808924032 2.60845388510298 0.8879656830425 - - - hypothetical protein 250568 1.24021780939042 2.68364469292243 0.918630970253561 - - - hypothetical protein 250569 1.29995125226951 2.73105032539041 0.990996374853024 - - - conserved protein 250570 1.3124837877808 2.94473028209359 0.92305652498531 2026 Cytotoxic translational repressor of toxin-antitoxin stability system JD conserved protein 250571 1.32658638774412 2.97364441213073 1.01706160682972 3177 Uncharacterized conserved protein S hypothetical protein 250572 1.37626090901441 3.10620356428519 0.964044170906499 2361 Uncharacterized conserved protein S nucleotidyltransferase 250573 1.33935838021934 3.06179346499512 0.978209891113546 1669 Predicted nucleotidyltransferases R nucleotidyltransferase 250574 1.41002329347166 3.12724622539164 1.03293534338045 1669 Predicted nucleotidyltransferases R nucleotidyltransferase 250575 1.29658545415027 2.90230073514483 0.968085937156179 4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V Type I restriction enzyme 250576 1.30346341504492 2.98816781359462 1.04115920746851 2509 Uncharacterized FAD-dependent dehydrogenases R hypothetical protein 250577 1.29223605396512 2.95229828170202 1.03859511990759 1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster R putative ATP-dependent helicase 250578 1.23630087386375 2.73231853884069 0.949353878158404 1704 Uncharacterized conserved protein S LemA protein 250579 1.31292322573792 3.11951881097807 1.09336957788671 4907 Predicted membrane protein S hypothetical protein 250580 1.30109248413467 2.94894440902688 1.03143193695298 4907 Predicted membrane protein S hypothetical protein 250581 1.43174393174637 3.34937617619383 1.04789708755772 1632 Ribosomal protein L15E J LSU ribosomal protein L15E 250582 1.33642703152519 2.93406992999225 1.00435300511661 1325 Predicted exosome subunit J hypothetical protein 250583 1.32036549385588 3.1189401140821 1.07990206317568 1603 RNase P/RNase MRP subunit p30 J hypothetical protein 250584 1.39194796975973 3.39353533848752 1.10035281182939 1369 RNase P/RNase MRP subunit POP5 J hypothetical protein 250585 1.27898781734376 2.88279280835043 1.02720806748524 638 20S proteasome, alpha and beta subunits O Proteasome, subunit-alpha 250586 1.37267991994587 3.08307787779579 1.06357343178492 1500 Predicted exosome subunit J hypothetical protein 250587 1.41001109821638 3.29484164894913 1.08610394108173 1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) J hypothetical protein 250588 1.31214934814777 2.74649274549845 0.965563202116974 689 RNase PH J Ribonuclease 250589 1.27323929697041 2.94026239435422 1.02523673728302 2123 RNase PH-related exoribonuclease J Ribonuclease 250590 1.3533010465846 3.13975652759864 1.12678120434602 1997 Ribosomal protein L37AE/L43A J LSU ribosomal protein L37AE 250591 1.35847546131634 2.86517769948371 1.0840552995222 1996 DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) K DNA-directed RNA polymerase subunit P 250592 1.3103311151556 3.03954446094942 0.996717600642244 2136 Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 dom JA conserved protein 250593 1.21695491265276 2.81747967302016 0.976169442549471 2892 Uncharacterized protein conserved in archaea S conserved protein 250594 1.29685048267987 2.94268130418145 1.05243834854016 3322 Predicted periplasmic ligand-binding sensor domain T hypothetical sensory transduction histidine kinase 250595 1.25596653522548 2.99044075302323 1.02474342737141 823 Periplasmic component of the Tol biopolymer transport system U conserved protein 250596 1.2689656081295 2.95122956489556 0.988472333367727 1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily R hypothetical protein 250597 1.2958171888877 3.00680792288717 1.05473851950205 281 Malic enzyme C NAD-dependent malic enzyme 250598 1.24070928518978 2.72505817113884 0.920689542598473 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H hypothetical protein 250599 1.29775610654406 3.06527809843757 1.0781732096763 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C putative pyruvate:ferredoxin oxidoreductase 250600 1.30383945085542 3.08310103971428 1.06769700552284 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C putative pyruvate:ferredoxin oxidoreductase 250601 1.32721035324486 3.0433234962239 1.01817577281713 1541 Coenzyme F390 synthetase H Coenzyme F390 synthetase 250602 1.3265075517505 3.14224088028633 1.08498042717592 3264 Small-conductance mechanosensitive channel M hypothetical protein 250603 1.25765388696745 2.87809970820976 1.02305619337337 2335 Secreted and surface protein containing fasciclin-like repeats M hypothetical protein 250604 1.34009074011003 3.31995340295168 1.12212058022157 - - - conserved protein 250605 1.31652287722427 2.99947738353035 1.0428844898941 598 Mg2+ and Co2+ transporters P Magnesium and cobalt transport protein CorA 250606 1.26990212008018 2.9357645128892 1.03442243329955 2430 Uncharacterized conserved protein S conserved protein 250607 1.318228733527 3.18285350717777 1.08592874174757 668 Small-conductance mechanosensitive channel M hypothetical protein 250608 1.28805738877522 2.94118784259819 1.01592517054078 1335 Amidases related to nicotinamidase Q hypothetical protein 250609 1.39402260700488 3.10845483084802 1.03097075220501 1977 Molybdopterin converting factor, small subunit H putative molybdopterin converting factor 250610 1.3118161203718 3.04143464939221 1.07289109679278 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase 250611 1.293973557906 2.84862852328802 1.01134658806489 3920 Signal transduction histidine kinase T sensory transduction protein kinase 250612 1.42243477699682 3.06997179149245 0.901317253036258 - - - Transposase 250613 1.27374214188228 3.00029799046844 1.03030073499797 2122 Uncharacterized conserved protein S hypothetical protein 250614 1.32314087969993 3.00165749310621 1.02595491184963 436 Aspartate/tyrosine/aromatic aminotransferase E Aspartate aminotransferase 250615 1.47063887068878 3.45174800022322 1.11283460998106 596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R hydrolase 250616 1.33451539216916 3.25608560523242 1.0624649880297 - - - hypothetical protein 250617 1.26483968717154 2.88964667446229 1.04490294427084 4090 Uncharacterized protein conserved in archaea S hypothetical protein 250618 1.26749598320282 2.92037365160099 0.98683503928418 3252 Methenyltetrahydromethanopterin cyclohydrolase H N5,N10-methenyltetrahydromethanopterin cyclohydrolase 250619 1.30254998669161 2.99717003732488 1.06191438374793 826 Collagenase and related proteases O hypothetical protein 250620 1.38785809521178 3.40181109509285 1.1193933024653 1835 Predicted acyltransferases I hypothetical protein 250621 1.31260018917888 2.95519030031309 0.993559025389809 1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 O Peptidyl-prolyl cis-trans isomerase 250622 1.28307122494423 2.96068766730019 1.0070361183253 864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-bin K transcriptional regulator 250623 1.26011555825212 2.82299265943471 0.910225316997669 456 Acetyltransferases R Acetyltransferase 250624 1.26423434424863 2.77688200616552 0.967361467278127 456 Acetyltransferases R Acetyltransferase 250625 1.28546350919707 3.13131121601642 1.09441418708274 530 Ca2+/Na+ antiporter P sodium-calcium exchanger protein 250626 1.28142687505873 3.10341129060605 1.08349840057445 3603 Uncharacterized conserved protein S hypothetical protein 250627 1.32709196416994 3.25803473912516 1.12172229218559 1115 Na+/alanine symporter E Na(+)-linked D-alanine glycine permease 250628 1.27690278465228 2.99386073058363 1.03942839977833 1361 S-layer domain M conserved protein 250629 1.30457347454356 3.09947599206554 1.06612100830747 4591 ABC-type transport system, involved in lipoprotein release, permease component M conserved protein 250630 1.29481897313851 2.92940910275294 0.995371253292439 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 250631 1.338932667901 3.09501360731693 1.0473105593096 - - - conserved protein 250632 1.26839001918372 2.8147213709919 0.975273408651071 714 MoxR-like ATPases R MoxR-like ATPase 250633 1.26562168719143 2.93459177463553 1.00655407557488 1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) R hypothetical protein 250634 1.31051581413378 3.10180006125294 1.07545077894008 - - - conserved protein 250635 1.28975025521786 3.0752474480874 1.08622380177563 - - - hypothetical protein 250636 1.27644138671957 3.10220337362551 1.10515406453334 628 Predicted permease R hypothetical protein 250637 1.30005664714812 2.81128442299672 1.0344598823043 - - - conserved protein 250638 1.30259387335998 2.96078837457635 0.98254287187346 - - - hypothetical protein 250639 1.32296246963157 2.99933837261262 1.05283479651732 - - - conserved protein 250640 1.27694060429451 2.85230713251675 0.984909137098352 4826 Serine protease inhibitor O Serine protease inhibitor 250641 1.31486107598169 2.90209008267569 1.00403863407762 - - - conserved protein 250642 1.23896729265005 2.38621677928852 0.987062358337653 - - - conserved protein 250643 1.57512510816076 3.53365879925961 1.04101238744586 - - - hypothetical protein 250644 1.3245951091183 2.89742602514858 0.959859735454795 5483 Uncharacterized conserved protein S conserved protein 250645 1.34684336402753 2.87738894469737 0.962170858968355 2026 Cytotoxic translational repressor of toxin-antitoxin stability system JD conserved protein 250646 1.35981112868357 2.86772509127414 0.859267348187705 - - - hypothetical protein 250647 1.41507564213085 3.19551790913323 1.04309188918942 4584 Transposase and inactivated derivatives L Transposase 250648 1.43535426219039 3.28109028190699 1.0707578392422 3344 Retron-type reverse transcriptase L reverse transcriptase 250649 1.26295837257684 2.60315946481301 1.01792155795332 - - - Transposase 250650 1.33853503384027 2.96497453032273 0.982607308007228 1484 DNA replication protein L Transposase 250651 1.37687120214938 3.05652275557522 0.993525012556023 5421 Transposase L Transposase 250652 1.42741458994452 3.13132848630883 0.837005767167631 - - - hypothetical protein 250653 1.37533171765344 3.09481648576078 0.902541935228087 1032 Fe-S oxidoreductase C hypothetical protein 250654 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 250655 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 250656 1.33104703762842 2.99801052568585 0.922877449883005 3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase R hypothetical protein 250657 1.42450037911303 3.29853921612864 0.965671413216483 1233 Phytoene dehydrogenase and related proteins Q hypothetical protein 250658 1.40916436469019 3.12999381589064 0.853561539956278 1244 Predicted Fe-S oxidoreductase R hypothetical protein 250659 1.48655011116932 3.31101597565428 1.0528582865186 4584 Transposase and inactivated derivatives L Transposase 250660 1.54971375608373 3.68876023588003 1.11138249186727 3344 Retron-type reverse transcriptase L reverse transcriptase 250661 1.51144680633226 3.32847885145195 1.0301030860429 1662 Transposase and inactivated derivatives, IS1 family L hypothetical protein 250662 1.50977604168181 3.42886429366285 0.996773076452362 3677 Transposase and inactivated derivatives L hypothetical protein 250663 1.3941100456324 3.10473307925708 0.996537755291593 3344 Retron-type reverse transcriptase L reverse transcriptase 250664 1.31766348988009 2.91188524920512 0.982721106916005 4584 Transposase and inactivated derivatives L Transposase 250665 1.28764176508487 2.84639587800077 0.95838637231126 1484 DNA replication protein L Transposase 250666 1.40632678313392 3.04367602400565 0.92404784320395 - - - hypothetical protein 250667 1.39057039206747 3.13941434519168 0.909501676367835 3593 Predicted ATP-dependent endonuclease of the OLD family L hypothetical protein 250668 1.39323298351982 3.17384551668371 1.00743567447569 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 250669 1.35178769363724 3.00972356298974 1.01663413547218 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system specificity subunit 250670 1.36105036750936 3.07755679260028 1.06333766535032 4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V type I restriction-modification system restriction subunit 250671 1.24032877016857 2.62406580794499 0.966245549931104 3937 Uncharacterized conserved protein S conserved protein 250672 1.24507085373101 2.77953893493207 0.941371598051828 - - - conserved protein 250673 1.26899094999132 2.67650025744335 0.918944271458219 - - - conserved protein 250674 1.31173424434187 2.96026566372863 1.01164189923875 - - - conserved protein 250675 1.27033560560926 2.8326638124899 0.956758240510752 - - - conserved protein 250676 1.32554143871232 3.07405602496339 1.01533168594711 2512 Uncharacterized membrane-associated protein/domain S conserved protein 250677 1.41725778928395 3.29086237113539 1.07465422998742 2061 ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase E conserved protein 250678 1.28846954796184 3.07360779009557 1.0680628925501 460 Homoserine dehydrogenase E Homoserine dehydrogenase 250679 1.32830363628269 3.08304825643012 1.06736619303129 1793 ATP-dependent DNA ligase L ATP-dependent DNA ligase 250680 1.33685452266432 3.06685471609671 1.05330727219505 218 Predicted GTPase R hypothetical protein 250681 1.27726897469599 2.90236018974192 0.988130373065406 608 Single-stranded DNA-specific exonuclease L conserved protein 250682 1.26468982534588 2.89385835862305 1.01644601615267 - - - conserved protein 250683 1.29600383416524 2.96093802191199 1.0235024395877 327 Uncharacterized conserved protein S hypothetical protein 250684 1.31739328495707 2.93650569272455 0.99119670088158 - - - conserved protein 250685 1.29382702942207 2.88163674458541 1.01717321266084 5010 Flp pilus assembly protein TadD, contains TPR repeats U hypothetical protein 250686 1.25059626078783 2.64893407828273 0.983437929465507 - - - conserved protein 250687 1.30775783531561 2.96330846252078 0.970599465507146 590 Cytosine/adenosine deaminases FJ hypothetical protein 250688 1.30279921265301 2.96820760610623 1.04517500062771 574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase G Phosphoenolpyruvate synthase 250689 1.29667753395639 2.75477767012582 1.06767482711884 - - - conserved protein 250690 1.34657655675033 2.97392640023911 0.935603555027497 1943 Transposase and inactivated derivatives L Transposase 250691 1.35908753142563 3.05558764975353 1.03059588419209 - - - hypothetical protein 250692 1.41639861066187 3.28444772395657 1.0097462626733 - - - conserved protein 250693 1.28783973226651 3.25946121244072 1.05213160099045 3391 Uncharacterized conserved protein S hypothetical protein 250694 1.32034656388466 2.92512455631191 0.956060708904845 1943 Transposase and inactivated derivatives L Transposase 250695 1.31798720873454 3.05368000819401 1.06715049388819 2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared wi K conserved protein 250696 1.29366990505698 3.21107065628437 1.1008249422187 2095 Multiple antibiotic transporter U Multiple antibiotic resistance protein 250697 1.35330186607184 2.9264585789094 1.00079997819911 - - - conserved protein 250698 1.30215812771296 2.84957340382011 1.02382488878556 610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V hypothetical protein 250699 1.32848935913808 2.9227123548053 0.990663611634781 - - - conserved protein 250700 1.47987646551703 3.33095820405089 1.09254293238852 - - - conserved protein 250701 1.30448286471933 2.86769403906151 0.979294556445577 - - - conserved protein 250702 1.36327618690356 2.88913603132713 0.999936001945434 - - - conserved protein 250703 1.37108580999796 2.96102345406365 0.998458906828957 - - - conserved protein 250704 1.40072486620164 3.15291674225127 1.01647388207345 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 250705 1.29820649022525 2.88690661543072 0.996008497025855 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system specificity subunit 250706 1.40296321627931 3.23880033490983 0.976696071169956 - - - hypothetical protein 250707 1.32248632493287 3.06484256473103 0.994680387185962 823 Periplasmic component of the Tol biopolymer transport system U hypothetical protein 250708 1.51778510026285 3.34446152237629 1.03260057570428 1051 ADP-ribose pyrophosphatase F hypothetical protein 250709 1.38830660342392 3.32327438373545 1.12957765304828 - - - conserved protein 250710 1.35140168251792 3.17416027227254 1.08403769167681 - - - conserved protein 250711 1.32660502982598 3.11077290329261 1.03906034518167 - - - conserved protein 250712 1.32275844997413 2.88706453529546 1.00388716884122 - - - hypothetical protein 250713 1.37582384597182 3.12918915646115 1.1024637992298 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250714 1.31256250048282 3.02191863156971 1.03244734380981 2195 Di- and tripeptidases E Aminoacyl-histidine dipeptidase 250715 1.35651469115884 3.23615267582474 1.0629692116419 2862 Predicted membrane protein S hypothetical protein 250716 1.35900233196308 3.21119087993737 1.04608529369257 4803 Predicted membrane protein S conserved protein 250717 1.3798547284266 3.47639723199726 1.1796324236097 628 Predicted permease R hypothetical protein 250718 1.39037423924429 3.00167541796518 0.916045169161078 - - - hypothetical protein 250719 1.29506282994162 2.91392615340674 0.877143195349784 5519 Superfamily II helicase and inactivated derivatives L conserved protein 250720 1.26206579813902 2.78927141486414 0.853517091349701 - - - hypothetical protein 250721 1.35761835880932 2.94847821719979 0.936566329090822 - - - hypothetical protein 250722 1.40880896727065 2.92135077144564 0.920088928881671 - - - hypothetical protein 250723 1.41557988146892 3.19357418195537 1.01004188679672 - - - hypothetical protein 250724 1.29635822994151 2.98762653921944 1.01586474840365 - - - hypothetical protein 250725 1.36936244827529 3.14824702596643 0.987600464255746 - - - hypothetical protein 250726 1.33878590014915 2.90373250528643 0.948174184996255 - - - hypothetical protein 250727 1.3079220697153 3.39489796611135 1.09285704934761 - - - hypothetical protein 250728 1.37222125843964 3.06397553190068 0.904140143439355 1961 Site-specific recombinases, DNA invertase Pin homologs L putative DNA recombinase 250729 1.26694403342966 2.4847777623609 0.878325970645877 - - - hypothetical protein 250730 1.34660230944458 2.99284844696672 1.01423348760538 - - - hypothetical protein 250731 1.39366961257756 3.0908996485417 1.00602159893417 - - - hypothetical protein 250732 1.42044882431048 3.11660401135166 0.968989051771042 - - - hypothetical protein 250733 1.4413863156472 3.25483473116792 1.07154365303505 4894 Uncharacterized conserved protein S conserved protein 250734 1.32082434725329 3.06557003211128 1.0782413788519 1454 Alcohol dehydrogenase, class IV C Iron-containing alcohol dehydrogenase 250735 1.29717964543324 3.03563813408359 1.06792235303574 3408 Glycogen debranching enzyme G Glycogen debranching enzyme 250736 1.35110725837847 3.117303600963 1.0387879270797 2152 Predicted glycosylase G conserved protein 250737 1.30229257472732 3.01443226719349 0.986348876518958 - - - conserved protein 250738 1.28280564350722 2.87355405677198 1.00099773256585 642 Signal transduction histidine kinase T Two component system histidine kinase 250739 1.45281946760558 3.59527161455308 1.09962351297644 - - - conserved protein 250740 1.55257676854208 3.85901018839447 1.19918362648506 2339 Predicted membrane protein S conserved protein 250741 1.55223238992812 3.49083498327278 1.00396630588097 - - - hypothetical protein 250742 1.36593318029954 3.23192823833139 1.04331502798589 1254 Acylphosphatases C Acylphosphatase 250743 1.29951451369315 3.00863129997025 1.04409992992188 53 Predicted Co/Zn/Cd cation transporters P Cobalt-zinc-cadmium resistance protein 250744 1.25841229119517 2.9257068011956 1.01494488700436 696 Phosphoglyceromutase G putative phosphoglycerate mutase 250745 1.28334886049008 2.91174167644185 1.0240071632859 1578 Uncharacterized conserved protein S hypothetical protein 250746 1.34997006937873 3.27057025360125 1.09117169801524 - - - conserved protein 250747 1.23684861488596 2.83858192519022 1.00880020854006 57 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase G Glyceraldehyde 3-phosphate dehydrogenase 250748 1.35791451766346 3.28753888327369 1.10708503295308 483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family G Suppressor protein SuhB homolog 250749 1.29518490186812 3.0533519738845 1.0525264941043 61 Predicted sugar kinase G hypothetical protein 250750 1.29285642574266 2.93310239259298 1.0279099301607 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase 250751 1.33322233346544 3.11451842820719 1.04448583442653 - - - conserved protein 250752 1.2647986876019 2.82993102236727 1.00579130664169 - - - conserved protein 250753 1.30739685816873 3.11954086642326 1.08896073268378 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C indolepyruvate ferredoxin oxidoreductase, subunit alpha 250754 1.30671969977207 3.0579525785576 1.06385996702882 1571 Predicted DNA-binding protein containing a Zn-ribbon domain R hypothetical protein 250755 1.31539692495478 3.01628511899051 1.01115841844809 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 250756 1.28364749167439 2.98958438125517 1.00385778502821 2003 DNA repair proteins L DNA repair protein 250757 1.29137995342119 2.95329291403813 1.00626682934105 314 Molybdopterin converting factor, large subunit H Molybdopterin converting factor, subunit 2 250758 1.34871662769497 3.00979527528725 1.00514553384028 746 Molybdopterin-guanine dinucleotide biosynthesis protein A H Molybdopterin-guanine dinucleotide biosynthesis protein 250759 1.28599238196556 2.92841515295843 1.01350736144307 5418 Predicted secreted protein S hypothetical protein 250760 1.30429565981543 3.21140751016085 1.11607817000056 - - - conserved protein 250761 1.29085077517357 2.92158442368315 1.02568227225245 37 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control D conserved protein 250762 1.28931202886971 2.90466669778811 1.01098436954105 1741 Pirin-related protein R Pirin 250763 1.33010173136776 3.32484913542542 1.1474571404731 1784 Predicted membrane protein S conserved protein 250764 1.46862080292894 3.30169712053291 0.97954379858167 1943 Transposase and inactivated derivatives L Transposase 250765 1.30113339477821 2.89211196157264 1.00543589133274 - - - conserved protein 250766 1.34006012748651 3.02945572844243 1.05205625831055 3063 Tfp pilus assembly protein PilF NU hypothetical protein 250767 1.30686421627156 2.81964308819449 0.967642635428754 3063 Tfp pilus assembly protein PilF NU hypothetical protein 250768 1.2887440873922 2.93141562431168 1.03465114871724 3640 CO dehydrogenase maturation factor D Carbon monoxide dehydrogenase accessory protein 250769 1.24788704484839 2.91769806768306 1.03290794977064 - - - conserved protein 250770 1.24596304313047 2.84690909122283 0.981666729523738 367 Asparagine synthase (glutamine-hydrolyzing) E Asparagine synthetase [glutamine-hydrolyzing] 250771 1.17206455448626 2.5122115907871 0.974857099634317 1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component F hypothetical protein 250772 1.24967011857548 2.86913381596776 1.00903222827557 47 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain F Phosphoribosylformylglycinamidine synthase 250773 1.28886619068895 2.91961076847278 0.973585220239124 1262 Uncharacterized conserved protein S conserved protein 250774 1.29522990945178 2.92520558623324 0.992575437614161 4742 Predicted transcriptional regulator K conserved protein 250775 1.30801917642665 2.87911516547482 0.971816705847687 4923 Uncharacterized conserved protein S conserved protein 250776 1.28040024178213 2.83332139787568 1.00299875570557 4127 Uncharacterized conserved protein S conserved protein 250777 1.28400212976807 2.94501708194101 1.02672176249059 72 Phenylalanyl-tRNA synthetase beta subunit J Phenylalanyl-tRNA synthetase, beta chain 250778 1.33205258402854 2.90288022224671 0.996633611498845 2102 Predicted ATPases of PP-loop superfamily R hypothetical protein 250779 1.30188920961544 2.90059768634744 1.0072044907227 164 Ribonuclease HII L Ribonuclease 250780 1.30123847932044 3.06155703693901 1.01066914051113 1237 Metal-dependent hydrolases of the beta-lactamase superfamily II R metal dependent hydrolase 250781 1.30040510524702 2.8296466858584 0.993058749929186 - - - conserved protein 250782 1.25731064357504 2.89670063154973 0.989238847695911 512 Anthranilate/para-aminobenzoate synthases component II EH Anthranilate synthase, component II 250783 1.27140177353112 2.92384509942423 1.0269201282664 147 Anthranilate/para-aminobenzoate synthases component I EH Anthranilate synthase, component I 250784 1.23743276234552 2.97208819694609 1.05419484198451 135 Phosphoribosylanthranilate isomerase E N-(5'-phosphoribosyl)anthranilate isomerase 250785 1.26887041414974 2.94648976504966 1.03766731346743 547 Anthranilate phosphoribosyltransferase E Anthranilate phosphoribosyltransferase 250786 1.27188564507933 2.9522062638862 1.02582402261644 159 Tryptophan synthase alpha chain E Tryptophan synthase, alpha chain 250787 1.28974540124115 2.95397536531033 1.01807380498327 133 Tryptophan synthase beta chain E Tryptophan synthase, beta chain 250788 1.35366838623896 3.13721543857237 1.07315644005541 134 Indole-3-glycerol phosphate synthase E Indole-3-glycerol phosphate synthase 250789 1.28403497218842 2.84638597145827 1.00268464014179 2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-depend C glucose-6-phosphate dehydrogenase [coenzyme F420 dependent] 250790 1.34173998587076 3.01858118303525 0.990111155034253 1878 Predicted metal-dependent hydrolase R hypothetical protein 250791 1.3410902659631 3.00834815904576 0.9653554381553 - - - conserved protein 250792 1.35390607574474 3.05862931693697 1.05831201432008 3408 Glycogen debranching enzyme G hypothetical protein 250793 1.25232192805471 2.97209067618799 1.02917610512248 - - - conserved protein 250794 1.2615831217371 2.82947537295213 0.95988734688508 652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family O Peptidyl-prolyl cis-trans isomerase 250795 1.3027305220995 3.01520423875342 1.05933732516657 209 Ribonucleotide reductase, alpha subunit F Ribonucleoside-diphosphate 250796 1.26670750616181 3.09933017748184 1.09228558497552 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER ABC-Type transporter, permease protein 250797 1.36910128422165 3.47040602280701 1.20258027551277 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER ABC-Type transporter, permease protein 250798 1.30447910376562 3.0520174369027 1.0654914495132 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 250799 1.32094478816688 2.97069416724912 1.03220850800143 1661 Predicted DNA-binding protein with PD1-like DNA-binding motif R hypothetical protein 250800 1.39906224365433 3.13776642425879 1.04394339459117 4738 Predicted transcriptional regulator K hypothetical protein 250801 1.28135555063283 2.92393482458177 1.03361090071229 148 Enolase G Enolase 250802 1.35117523854173 3.06505477904006 0.928487663413068 3547 Transposase and inactivated derivatives L Transposase 250803 1.37936655383845 3.02447012271125 0.959251814366612 - - - conserved protein 250804 1.30340516823366 3.01477844810935 1.06203336579902 714 MoxR-like ATPases R MoxR-like ATPase 250805 1.32330866534021 3.07827388638503 1.06816098665924 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R hypothetical protein 250806 1.31196362766774 3.04980544483966 1.04956559063852 28 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome) EH Acetolactate synthase 250807 1.25624564661234 2.74931929028082 0.952145440295048 3467 Predicted flavin-nucleotide-binding protein R 5-nitroimidazole antibiotic resistance protein 250808 1.41325994688507 3.25537993496483 0.908697245392021 - - - hypothetical protein 250809 1.28181759294203 3.10858026668987 1.07675021559061 - - - hypothetical protein 250810 1.2848346156229 2.83872999934054 0.923171692144274 2940 Proteins containing SET domain R hypothetical protein 250811 1.31092428056529 3.23165726173725 1.12775348836858 531 Amino acid transporters E Putrescine-ornithine antiporter 250812 1.31852655399613 3.24280322706499 1.1152542771191 531 Amino acid transporters E Amino acid permease 250813 1.28757516341287 2.79645407784581 0.954930920827732 - - - conserved protein 250814 1.3205722464985 3.30670200906214 1.1379687140884 730 Predicted permeases R hypothetical permease 250815 1.25629575957602 2.95194327648717 1.03175476577739 4591 ABC-type transport system, involved in lipoprotein release, permease component M ABC transporter, permease protein 250816 1.34177229312211 3.04706874770522 1.01136616116399 1846 Transcriptional regulators K transcriptional regulator, MarR family 250817 1.33630743696218 3.22097731848468 1.14031989053391 1033 Predicted exporters of the RND superfamily R Membrane protein related to SecD/SecF 250818 1.27921943276502 2.92789883861788 1.01833314183517 1846 Transcriptional regulators K hypothetical protein 250819 1.39312578482267 3.15896399482143 0.999317537618946 1378 Predicted transcriptional regulators K hypothetical protein 250820 1.29897076575988 3.1333226057676 1.09705124235663 628 Predicted permease R ABC transporter, permease protein 250821 1.30903842166164 2.94819370330185 1.01803720572346 1131 ABC-type multidrug transport system, ATPase component V ABC transporter, ATP-binding protein 250822 1.25652176795619 3.13808059223402 1.09245033529049 - - - hypothetical protein 250823 1.38622440020731 3.20619080896516 1.02290806927463 - - - Potassium channel protein 250824 1.24766384388912 2.92391778644599 1.00278835956356 4022 Uncharacterized protein conserved in archaea S hypothetical protein 250825 1.31879120358077 3.04993045735415 1.05409852442111 4746 Uncharacterized protein conserved in archaea S conserved protein 250826 1.32979322504477 2.97500556280192 1.03515876616855 - - - transcriptional regulator, ArsR family 250827 1.25322727712525 2.91867751462299 1.02704386395104 4022 Uncharacterized protein conserved in archaea S hypothetical protein 250828 1.37701182415837 3.08057580388799 1.10672732128695 - - - conserved protein 250829 1.27762981824966 3.08444882751069 1.04867138237041 - - - conserved protein 250830 1.36243741581661 3.13222691684969 1.06835808022113 - - - conserved protein 250831 1.32688089058922 3.06035229170446 1.0683685624148 - - - conserved protein 250832 1.26171278122564 2.82784589940501 0.953465327105495 1541 Coenzyme F390 synthetase H Coenzyme F390 synthetase/phenylacetyl-CoA Ligase 250833 1.45555161221991 3.51289791554328 1.07968633342535 - - - conserved protein 250834 1.33675583645622 3.23177572052489 1.05641360858546 2020 Putative protein-S-isoprenylcysteine methyltransferase O hypothetical protein 250835 1.3844989646406 3.34079354581654 1.06041710495454 - - - hypothetical protein 250836 1.33949513938979 3.11960591737738 1.06561328269826 3326 Predicted membrane protein S hypothetical protein 250837 1.37778461162289 2.9103015426999 1.01312635033489 1633 Uncharacterized conserved protein S methyltransferase 250838 1.31623619071277 3.06135918505258 1.06144256014672 2133 Glucose/sorbosone dehydrogenases G L-sorbosone dehydrogenase 250839 1.39721548262491 3.21855392390209 1.06028107991231 - - - conserved protein 250840 1.40539230559593 3.59674071545139 1.1852722266162 - - - hypothetical protein 250841 1.29345720042167 3.05016170862344 1.06626398226965 389 Nucleotidyltransferase/DNA polymerase involved in DNA repair L DNA polymerase IV 250842 1.26701240639133 3.04157981385802 1.04819237802535 628 Predicted permease R hypothetical protein 250843 1.30739020073971 2.97203386434574 1.00829058670236 616 Periplasmic serine proteases (ClpP class) OU hypothetical protein 250844 1.27680625967075 2.8515968291072 0.987726472877109 - - - tetratricopeptide repeat family protein 250845 1.26282111277497 2.87355476783571 0.974568740351842 2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains T Response regulator 250846 1.2874414025454 2.98139230703004 1.06405570582985 642 Signal transduction histidine kinase T Sensor histidine kinase/response regulator 250847 1.26581673859313 2.83261030328224 0.968533713475153 - - - conserved protein 250848 1.2701858862229 2.79147520556521 0.965985251564351 1801 Uncharacterized conserved protein S hypothetical protein 250849 1.24384604010995 2.80388779646764 0.969392336379029 - - - conserved protein 250850 1.3043602915024 2.96752044278544 1.00927162053559 739 Membrane proteins related to metalloendopeptidases M putative metalloendopeptidases 250851 1.27313020766885 2.81305668390434 0.988716482028496 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250852 1.27465541400893 2.81776559641268 1.01497862556754 - - - conserved protein 250853 1.30555960458132 2.92895465543749 1.00638013489103 2231 Uncharacterized protein related to Endonuclease III L Endonuclease III 250854 1.32029523924937 3.19464966897485 1.07979884592805 3431 Predicted membrane protein S hypothetical protein 250855 1.22784157473503 2.42839995987092 0.867294379869375 - - - hypothetical protein 250856 1.30328108063224 3.08907901240223 1.08415427862946 4591 ABC-type transport system, involved in lipoprotein release, permease component M ABC transporter, permease protein 250857 1.30809793430772 3.0491305364385 1.04595505624432 - - - ABC transporter, permease protein 250858 1.27172936205375 2.98564988700792 1.06345867746215 1361 S-layer domain M hypothetical protein 250859 1.23976721199123 2.81762562369113 0.983551035433622 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 250860 1.26897231269375 2.84715128847215 1.02015568323976 1476 Predicted transcriptional regulators K transcriptional regulator 250861 1.28202732254696 3.03526683087711 1.02281909277354 - - - hypothetical protein 250862 1.35064455542927 3.04643016098038 1.0347709604733 1741 Pirin-related protein R Pirin 250863 1.32509003919134 2.87598892612587 0.893686218433335 - - - conserved protein 250864 1.47303158780252 3.49294718121367 1.09205756265397 - - - conserved protein 250865 1.38294024006858 3.0148118662698 0.91884985833936 - - - conserved protein 250866 1.40576498481153 3.19189465294255 0.969671095132451 - - - Transposase 250867 1.45348972227049 3.15984342432437 0.97149382342748 - - - Transposase 250868 1.37440882427442 3.05135462212517 0.940329283389608 3666 Transposase and inactivated derivatives L Transposase 250869 1.43809441692702 3.12637448841814 0.970116843251659 - - - Transposase 250870 1.40576498481153 3.19189465294255 0.969671095132451 - - - Transposase 250871 1.46862080292894 3.30169712053291 0.97954379858167 1943 Transposase and inactivated derivatives L Transposase 250872 1.36770819564481 3.08200398444658 1.04234291442448 1741 Pirin-related protein R Pirin 250873 1.36015456563097 3.11509616406577 1.03179337528407 - - - hypothetical protein 250874 1.34073495423478 2.99622374650935 1.00096838861761 4079 Uncharacterized protein conserved in archaea S conserved protein 250875 1.29844119270529 2.98274147746531 1.04478840139119 1001 Adenine deaminase F Adenine deaminase 250876 1.40326811983175 3.22712054920591 1.03436225023984 1932 Phosphoserine aminotransferase HE Phosphoserine aminotransferase 250877 1.3115113076271 3.05102905545315 1.08732239182676 146 N-methylhydantoinase B/acetone carboxylase, alpha subunit EQ 5-oxoprolinase 250878 1.24461496897485 2.88647011410225 1.01523237091486 1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) R conserved protein 250879 1.2745429118556 2.979173533927 0.989885296697359 - - - conserved protein 250880 1.4163868535963 3.21746365345866 1.0642768324119 - - - hypothetical protein 250881 1.29312401337672 3.0372394991438 1.02077650210099 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R flavoredoxin 250882 1.26213209736875 2.77857985363546 0.966617853124727 1453 Predicted oxidoreductases of the aldo/keto reductase family R oxidoreductase, ALDO/KETO reductase family 250883 1.28552427797453 2.86251880488383 1.0001068139589 1453 Predicted oxidoreductases of the aldo/keto reductase family R oxidoreductase, ALDO/KETO reductase family 250884 1.30101294542495 2.96108303239458 0.961287502333529 599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit S hypothetical protein 250885 1.23913053907502 2.8917511358025 1.01048429913794 1670 Acetyltransferases, including N-acetylases of ribosomal proteins J Ribosomal-protein-alanine acetyltransferase 250886 1.29022299914864 2.94914473445048 1.02742692158844 - - - hypothetical protein 250887 1.33188383393116 3.20645122879603 1.03363961988519 - - - hypothetical protein 250888 1.26664306043471 2.91430249097221 0.993555431077803 3391 Uncharacterized conserved protein S hypothetical protein 250889 1.31896657738709 3.26884462410033 1.12653323781057 1295 Predicted membrane protein S Ribonuclease BN 250890 1.27585541061666 3.03656586862165 1.01496000532739 - - - hypothetical protein 250891 1.45929595926445 3.36289848878927 0.996407940603278 - - - hypothetical protein 250892 1.30772344768646 3.21275525206146 1.09770909119319 2244 Membrane protein involved in the export of O-antigen and teichoic acid R Heteropolysaccharide repeat unit export protein 250893 1.27897374256564 2.76032829382213 0.894393041949425 - - - hypothetical protein 250894 1.33585071895955 2.9051617279239 0.990367871440815 - - - hypothetical protein 250895 1.24948274184614 2.77949785431511 0.978646826154602 4198 Uncharacterized conserved protein S hypothetical protein 250896 1.32233818114202 3.0064726195868 1.03819157056784 607 Rhodanese-related sulfurtransferase P hydrolase 250897 1.41041081444898 3.23573877548351 1.05170537587969 - - - conserved protein 250898 1.26791047591505 2.93929413596441 1.01741785255004 1470 Predicted membrane protein S conserved protein 250899 1.34858993746485 2.92596171295596 0.898544206318828 - - - conserved protein 250900 1.23472809254764 2.90597148623065 1.0093153514918 432 Uncharacterized conserved protein S hypothetical protein 250901 1.47170114598985 3.37528972476978 0.996150167434837 1943 Transposase and inactivated derivatives L Transposase 250902 1.32922091023573 3.17357175307591 1.09484627006416 3291 FOG: PKD repeat R conserved protein 250903 1.26663595600705 2.98034079717115 1.0456337946408 - - - conserved protein 250904 1.34107465965527 3.0023405171804 0.928750053364632 1045 Serine acetyltransferase E Serine O-acetyltransferase 250905 1.36830064329745 3.07707792762199 0.966665065552726 - - - conserved protein 250906 1.31750275055806 3.07054161864293 1.08119124955962 1234 Metal-dependent hydrolases of the beta-lactamase superfamily III R metal dependent hydrolase 250907 1.28991391429441 3.08378907933899 1.01104989316189 - - - conserved protein 250908 1.29613166563487 2.94094000172262 1.04006465596709 662 Mannose-6-phosphate isomerase G Lipopolysaccharide N-acetylglucosaminyltransferase 250909 1.29859185142598 2.99037642265849 1.03232947988343 2152 Predicted glycosylase G conserved protein 250910 1.32025787858409 2.97410413398482 1.05570311198006 - - - Mannosyltransferase 250911 1.2636432826126 3.02431410513029 1.07496315375879 - - - hypothetical protein 250912 1.32298094081079 2.86016560333353 0.90080924077676 - - - conserved protein 250913 1.24154579340837 2.80176122309526 0.98031683033451 - - - conserved protein 250914 1.39586288508193 3.2334466846798 1.03046637222116 - - - hypothetical protein 250915 1.281798682286 3.02888206716715 1.00117976871252 - - - conserved protein 250916 1.24708506114824 2.76491224410634 0.976090376875475 - - - hypothetical protein 250917 1.30960419449547 2.87115112932743 1.01714817631095 2326 Uncharacterized conserved protein S conserved protein 250918 1.37916088903159 3.14283311262034 1.02249924425514 784 FOG: CheY-like receiver T transcriptional regulator 250919 1.31968912819624 2.95631827989341 0.974935244329516 784 FOG: CheY-like receiver T transcriptional regulator 250920 1.26029992414611 2.8550622217186 1.01507196481225 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250921 1.28677872942014 2.98589601766969 1.04999998849086 4742 Predicted transcriptional regulator K conserved protein 250922 1.40488317803489 3.12803684287674 1.02053510107358 3328 Transposase and inactivated derivatives L Transposase 250923 1.29565241925709 2.882972589462 1.00251523719858 4742 Predicted transcriptional regulator K conserved protein 250924 1.2697315941807 2.80445740495373 0.984039810701024 - - - hypothetical protein 250925 1.34259372782528 2.74758670923867 0.945077880686183 - - - hypothetical protein 250926 1.27526207790571 2.91569103840645 1.03307204719989 5012 Predicted cobalamin binding protein R dimethylamine corrinoid protein 250927 1.28526641204103 2.94768050069955 0.973402052243386 - - - dimethylamine:corrinoid methyltransferase 250928 1.37833541322819 3.10300068071151 1.05208185822766 - - - dimethylamine:corrinoid methyltransferase 250929 1.31679559096125 3.17934045408575 1.08241659392666 531 Amino acid transporters E Dimethylamine permease 250930 1.26844749564326 2.88010468128762 1.02877469113431 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250931 1.46815434457251 3.4075726578242 1.12107650584513 2248 Predicted hydrolase (metallo-beta-lactamase superfamily) R conserved protein 250932 1.29696578558861 2.93369163709159 1.02022148071827 60 Isoleucyl-tRNA synthetase J Isoleucyl-tRNA synthetase 250933 1.32642587708266 2.99760189617697 1.01422200227846 1634 Uncharacterized Rossmann fold enzyme R conserved protein 250934 1.28304297858049 2.82502669910132 0.945547439805235 - - - conserved protein 250935 1.28221521887825 2.7345133684117 0.928626130604494 - - - conserved protein 250936 1.31714256755967 2.85422554081621 1.00293297483152 - - - conserved protein 250937 1.29456427760167 2.8767526523223 1.0056576041013 1373 Predicted ATPase (AAA+ superfamily) R hypothetical protein 250938 1.33096062995808 2.99174253375489 1.0357240429625 1057 Nicotinic acid mononucleotide adenylyltransferase H hypothetical protein 250939 1.28191936157156 2.86135159252942 0.948384294484902 - - - hypothetical protein 250940 1.33382569467582 2.98550583498847 1.01544319852481 - - - hypothetical protein 250941 1.36158309814007 3.01126182658472 1.03317702403728 610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V type I restriction-modification system restriction subunit 250942 1.43541594079338 3.14168446111599 1.01006088526904 - - - hypothetical protein 250943 1.51064112438132 3.43633307560032 1.09880651398319 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 250944 1.50298469041293 3.30081929340105 1.06971223772154 4804 Uncharacterized conserved protein S hypothetical protein 250945 1.6157864191241 3.54057894776552 1.06251825584044 - - - hypothetical protein 250946 1.36795861115347 3.07188850396331 1.05765330753488 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system specificity subunit 250947 1.36398128937635 3.09571707206324 0.959861897430991 3467 Predicted flavin-nucleotide-binding protein R antibiotic resistance protein 250948 1.43100171647725 3.2578007533882 1.09415795855072 - - - putative NADH oxidase 250949 1.25179650688327 2.57436402887817 0.949056954463849 - - - putative ferredoxin 250950 1.33012840393089 2.94099271107978 1.00357123803685 - - - transcriptional regulator, ArsR family 250951 1.26827539725773 2.57021488032461 1.01981396954801 - - - hypothetical protein 250952 1.32817691482314 3.0245982168656 1.06743626042198 4548 Nitric oxide reductase activation protein P hypothetical protein 250953 1.34702762996726 3.03738448244011 1.02015433917008 714 MoxR-like ATPases R conserved protein 250954 1.26273761501414 2.82162998287166 0.993807973033153 1313 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins R Pyruvate formate-lyase activating enzyme 250955 1.33076523900826 3.07377170370773 1.02743630690551 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 250956 1.32924461896716 2.92009896655452 1.01433501413605 - - - hypothetical protein 250957 1.24776871649135 2.85137071881673 1.00362158349858 778 Nitroreductase C putative NADH oxidase 250958 1.29147691911597 2.87309761089607 0.986034106723782 588 Phosphoglycerate mutase 1 G Phosphoglycerate mutase 250959 1.33226538531947 2.98004357943933 1.02992186270139 248 Exopolyphosphatase FP conserved protein 250960 1.28886430046965 2.99297790858685 0.938918245148339 - - - hypothetical protein 250961 1.2809380060685 2.96206736767293 0.919453642135665 - - - hypothetical protein 250962 1.38895806124836 3.2590851149898 0.971704458795972 - - - hypothetical protein 250963 1.25397538765097 2.66688845910353 0.886319914385789 - - - Transposase 250964 1.41980958985439 3.29186862426624 1.0111563360118 3415 Transposase and inactivated derivatives L Transposase 250965 1.26396336857388 2.90139678679552 1.01747759962692 1061 DNA or RNA helicases of superfamily II KL DNA repair helicase 250966 1.26815631919829 2.77643654263922 0.981515429300945 3372 Uncharacterized conserved protein S hypothetical protein 250967 1.42787801517082 3.29732555071069 1.09508821345632 - - - hypothetical protein 250968 1.27209371199504 2.72033359276896 1.04141557981852 - - - conserved protein 250969 1.31669576183472 3.23755333770752 1.12164337228065 - - - conserved protein 250970 1.28930566705662 2.81467103698492 0.982986170656642 2153 Predicted acyltransferase R Acetyltransferase 250971 1.26807196360704 2.92997902682781 0.985673231839628 467 RecA-superfamily ATPases implicated in signal transduction T putative resolvase/recombinase 250972 1.2550340692572 2.79067612607213 0.989600175186039 3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain KT putative transcriptional regulator 250973 1.22831019045581 2.93406897129076 1.0182740149248 467 RecA-superfamily ATPases implicated in signal transduction T putative resolvase/recombinase 250974 1.31507694372989 3.13101201388932 1.10446774788325 750 Predicted membrane-associated Zn-dependent proteases 1 M Membrane metalloprotease 250975 1.28879918714624 2.94676700635823 1.04903275824594 1324 Uncharacterized protein involved in tolerance to divalent cations P Periplasmic divalent cation tolerance protein 250976 1.26104254901045 3.02125117796619 1.04246365657199 - - - hypothetical protein 250977 1.32971288930764 3.08683688834394 1.0612430067945 4069 Uncharacterized protein conserved in archaea S hypothetical protein 250978 1.36301314283661 3.30271767350001 1.13287929011917 4591 ABC-type transport system, involved in lipoprotein release, permease component M ABC transporter, permease protein 250979 1.31131183232913 3.13961029791242 1.08357533020729 - - - conserved protein 250980 1.3377385351153 3.3158985703782 1.125128721661 1470 Predicted membrane protein S hypothetical protein 250981 1.35012026106679 3.0911160975953 1.0776933021564 1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase R Cobalt transport ATP-binding protein 250982 1.35542188201406 3.30814182012811 1.09857519292318 619 ABC-type cobalt transport system, permease component CbiQ and related transporters P ABC transporter, permease protein 250983 1.28653831799995 2.99150296118592 1.05890714390516 - - - conserved protein 250984 1.24819326929839 2.89884447079679 1.03078653624138 1572 Uncharacterized conserved protein S conserved protein 250985 1.27039204523389 3.00572002786045 1.04502697883433 - - - conserved protein 250986 1.31921463144356 3.07570112651257 1.02665226441759 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 250987 1.26654114817475 2.95181058607714 1.02673695190035 - - - conserved protein 250988 1.26656307011036 2.97069760513113 1.01330511657863 1572 Uncharacterized conserved protein S conserved protein 250989 1.25789010551101 3.07993313677968 1.08671148385151 1572 Uncharacterized conserved protein S conserved protein 250990 1.34738718994126 3.20350408562307 1.07298906124693 - - - hypothetical protein 250991 1.26445029070976 3.13704000077895 1.01942271788317 3391 Uncharacterized conserved protein S hypothetical protein 250992 1.32068301885285 2.90119796358567 0.978330503087314 5421 Transposase L Transposase 250993 1.43629373487156 3.30268750123178 1.02944780237161 590 Cytosine/adenosine deaminases FJ Deoxycytidylate deaminase 250994 1.48518030757925 3.45139677728418 0.995162972486377 346 Lactoylglutathione lyase and related lyases E Lactoylglutathione lyase 250995 1.3800951754055 2.94193978185519 0.915166832678234 727 Predicted Fe-S-cluster oxidoreductase R conserved protein 250996 1.43087018551246 3.44478527300749 1.06814922025269 - - - hypothetical protein 250997 1.4419588350922 3.19513469612874 1.03971529951888 3369 Uncharacterized conserved protein S conserved protein 250998 1.40655725546291 3.35041097361407 1.1357417097756 - - - conserved protein 250999 1.41547267213233 3.46795096739462 0.956892629895775 - - - conserved protein 251000 1.40163946272399 3.402351207507 1.11011228894433 - - - hypothetical protein 251001 1.37451729304341 3.19629901057201 0.980537628837927 - - - hypothetical protein 251002 1.23778201470314 2.70963370367001 0.867955193210374 1943 Transposase and inactivated derivatives L Transposase 251003 1.36008052136963 3.06447965987661 0.953740785045788 675 Transposase and inactivated derivatives L Transposase 251004 1.39191052690643 3.20507502258271 0.916966724261009 - - - hypothetical protein 251005 1.33932597551928 3.44110077591957 1.02257375531752 - - - hypothetical protein 251006 1.43142471393217 3.24114545833984 1.00999246427347 - - - hypothetical protein 251007 1.46115693711393 3.36709632079086 1.03380565126246 1035 Coenzyme F420-reducing hydrogenase, beta subunit C Coenzyme F420 hydrogenase, beta subunit 251008 1.42864942344998 3.22042214984272 0.988404876668756 1941 Coenzyme F420-reducing hydrogenase, gamma subunit C Coenzyme F420 hydrogenase, gamma subunit 251009 1.35294338159335 3.11739296075002 1.06683532636361 680 Ni,Fe-hydrogenase maturation factor C Coenzyme F420 hydrogenase, delta subunit 251010 1.36980283383844 3.14865454562773 1.02877634381845 3259 Coenzyme F420-reducing hydrogenase, alpha subunit C Coenzyme F420 hydrogenase, alpha subunit 251011 1.35831254205357 3.01122222759843 0.976402385248629 - - - conserved protein 251012 1.29140190534604 2.97282289507148 0.920290069017239 - - - Transposase 251013 1.35456119675804 3.23579795446342 1.00111153213086 - - - hypothetical protein 251014 1.39895358194282 3.27322124804016 1.02394304099943 - - - glycosyltransferase 251015 1.33702027568315 2.9392633713849 0.977561061231199 438 Glycosyltransferase M glycosyltransferase 251016 1.29101303300957 2.98997890056575 1.05357221332249 - - - hypothetical protein 251017 1.31587884582026 3.05306590949013 1.05416579051375 673 Predicted dehydrogenases and related proteins R oxidoreductase 251018 1.32566193070604 2.94667501366664 0.943517501690471 1541 Coenzyme F390 synthetase H CapK protein 251019 1.41855970748603 3.19803220996443 0.945178415393515 2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) M conserved protein 251020 1.44090687352848 3.49316243539458 1.09676804978811 - - - conserved protein 251021 1.22857852192239 2.87113318991693 1.01593200230706 2333 Predicted hydrolase (metallo-beta-lactamase superfamily) R Competence-like protein 251022 1.33735297584573 2.95329291908217 1.04851469701481 - - - hypothetical protein 251023 1.29089670425451 2.84466574443032 0.97049414134674 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 251024 1.39212821329421 3.13233699848576 1.07197051161353 - - - conserved protein 251025 1.48033330766887 3.46505104252777 1.0670162121632 - - - hypothetical protein 251026 1.39051988142474 3.20660375792072 1.12532249037045 - - - hypothetical protein 251027 1.47051078233842 3.42440437441935 1.10549275447849 - - - hypothetical protein 251028 1.40745703903627 3.36310740570864 1.12814549053224 1404 Subtilisin-like serine proteases O calcium dependent protease 251029 1.43313387281085 3.43845059571076 1.15546782861376 - - - hypothetical protein 251030 1.46354583898826 3.40136429239087 1.10516420431684 - - - hypothetical protein 251031 1.32053121538501 3.05023504856749 1.07138757572433 1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain C fumarate hydratase, alpha subunit 251032 1.25735827892848 2.8351256608399 0.958650834121974 1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain C fumarate hydratase, beta subunit 251033 1.31214811364245 2.97131868673163 1.00103071286857 4742 Predicted transcriptional regulator K conserved protein 251034 1.54541123460858 3.63748627190236 1.09608143788305 474 Cation transport ATPase P Cation-transporting ATPase 251035 1.42051477984103 3.05525916979781 0.94544569305527 2326 Uncharacterized conserved protein S hypothetical protein 251036 1.42989074048884 3.55869523082298 1.20844525163495 - - - putative membrane transport protein 251037 1.3472924845738 3.494328839713 1.18752092588017 3247 Uncharacterized conserved protein S hypothetical protein 251038 1.28820852239781 3.04454426140572 1.09130915457409 4870 Cysteine protease O surface layer protein B 251039 1.27261728880879 2.82470025650786 0.975125089738139 2042 Uncharacterized conserved protein S RNase P RNA component 251040 1.29255836342723 2.982514475542 0.99106201473623 1611 Predicted Rossmann fold nucleotide-binding protein R hypothetical protein 251041 1.2839372535293 2.88645682828067 1.03512767011006 550 Topoisomerase IA L DNA topoisomerase I 251042 1.32016839906335 3.21901070663813 1.0873890656207 589 Universal stress protein UspA and related nucleotide-binding proteins T putative transcriptional regulator 251043 1.26244886725375 2.88421712235148 1.02738392520674 1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing J mRNA 3'-end processing factor 251044 1.40136706923464 3.40241244862363 1.1232307435406 - - - hypothetical protein 251045 1.34469140565745 3.04162581994656 1.07162970416347 2433 Uncharacterized conserved protein S hypothetical protein 251046 1.30468715652808 2.83540898933344 0.988819802774473 478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain T Serine/threonine protein kinase 251047 1.36533394862592 3.37459381651308 1.13758095346458 - - - hypothetical protein 251048 1.274063743916 2.70618577578676 0.867316839143991 - - - conserved protein 251049 1.26827237221998 2.86282382463028 0.977089125093773 693 Putative intracellular protease/amidase R Protease I 251050 1.27622768723658 2.99068505793925 1.04538068249863 626 Cystathionine beta-lyases/cystathionine gamma-synthases E Cystathionine gamma-synthase 251051 1.29687705637297 2.95073539511047 1.03338980297495 1488 Nicotinic acid phosphoribosyltransferase H Nicotinate phosphoribosyltransferase 251052 1.26096288411148 3.10184287296177 1.04777196551547 823 Periplasmic component of the Tol biopolymer transport system U hypothetical protein 251053 1.26293549972327 2.92846030339015 1.0262182951716 663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily R Carbonic anhydrase 251054 1.29787620538016 3.13235944071291 1.08352643390433 - - - hypothetical protein 251055 1.32213513976625 3.0950470158833 1.01572016982794 1413 FOG: HEAT repeat C Phycocyanin alpha-subunit phycocyanobilin lyase related protein, CpcE/NblB family 251056 1.29208827249286 2.92820555298885 1.00519165668105 - - - hypothetical protein 251057 1.39345307425917 3.31039572446796 1.09294785160757 4189 Predicted transcriptional regulator K transcriptional regulator 251058 1.29012370991212 2.92026948775411 1.02552367210045 - - - hypothetical protein 251059 1.30634001986476 2.91482034155897 1.01756028727184 2512 Uncharacterized membrane-associated protein/domain S hypothetical protein 251060 1.29812438769303 3.00871384779642 1.0029352309107 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter, ATP-binding protein 251061 1.29942089689301 3.15197327791795 1.0678586913169 1361 S-layer domain M hypothetical protein 251062 1.29030266393215 3.02745288702612 1.01383098922805 1361 S-layer domain M hypothetical protein 251063 1.30541144182835 3.23878417847359 1.13860760143729 577 ABC-type antimicrobial peptide transport system, permease component V ABC transporter, permease protein 251064 1.30093266252588 3.00160410064636 1.0626124214447 3322 Predicted periplasmic ligand-binding sensor domain T Two component system histidine kinase 251065 1.31704732868618 2.88152674359707 0.955491294312089 727 Predicted Fe-S-cluster oxidoreductase R hypothetical protein 251066 1.28443387626843 2.89741354032195 1.02457671622297 3322 Predicted periplasmic ligand-binding sensor domain T Two component system histidine kinase 251067 1.28394254074863 3.00262750020222 1.05453963475484 - - - conserved protein 251068 1.17327093438381 2.53619443464363 0.954448620992846 - - - hypothetical protein 251069 1.23612582580029 2.80033487945098 0.951462989316473 3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase R hypothetical protein 251070 1.3792710006562 3.26750844211632 1.07751093344959 590 Cytosine/adenosine deaminases FJ putative cytosine deaminase 251071 1.26954368533513 2.98057761475258 0.987033953346608 2335 Secreted and surface protein containing fasciclin-like repeats M hypothetical protein 251072 1.32329294083618 2.92335472762023 0.955916451697459 3871 Uncharacterized stress protein (general stress protein 26) R hypothetical protein 251073 1.27945609989192 2.9237886530379 1.01233377296526 2203 FOG: GAF domain T hypothetical protein 251074 1.28065897885696 2.93685045541094 1.02367733076151 58 Glucan phosphorylase G Glycogen phosphorylase 251075 1.29442924150437 2.78939753679053 0.978050918098331 4783 Putative Zn-dependent protease, contains TPR repeats R hypothetical protein 251076 1.32590513438508 3.28758310184519 1.11744731256921 - - - hypothetical protein 251077 1.31630843392791 3.26024904294738 1.06735960401543 - - - conserved protein 251078 1.29902084883728 2.83942159687729 1.00000509183534 1164 Oligoendopeptidase F E Oligoendopeptidase F 251079 1.29973338538835 3.01936054481903 1.04565320938143 - - - conserved protein 251080 1.26461801778929 2.77310295650413 0.961099650429404 3177 Uncharacterized conserved protein S hypothetical protein 251081 1.39445316375243 3.24382396521567 1.09963960042067 2453 Predicted protein-tyrosine phosphatase T hypothetical protein 251082 1.36684851302628 3.02847871840251 1.00123658822162 1846 Transcriptional regulators K transcriptional regulator, MarR family 251083 1.27425980626109 2.92514106617927 1.02821268629913 466 ATP-dependent Lon protease, bacterial type O ATP-dependent protease La 251084 1.30403072032773 2.90693546714981 1.00672398474447 655 Multimeric flavodoxin WrbA R iron-sulfur flavoprotein 251085 1.27277234665622 3.03041483600496 1.03213464740363 1487 Predicted nucleic acid-binding protein, contains PIN domain R hypothetical protein 251086 1.40019021340085 3.51393331633628 1.18404980195023 2814 Arabinose efflux permease G hypothetical protein 251087 1.31988549148264 3.03740708586328 1.04859430404393 596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R putative hydrolase 251088 1.31864148020349 3.19593113402279 1.07566778581099 1280 Putative threonine efflux protein E hypothetical protein 251089 1.30800077183684 2.90725274612809 0.827725835361169 - - - hypothetical protein 251090 1.40373871908441 3.1803656663302 0.995397479937151 1518 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 251091 1.34061882898745 3.15368661509633 1.02905917602863 - - - hypothetical protein 251092 1.31357694412661 2.91425871071466 0.989718773635611 - - - hypothetical protein 251093 1.37698059782337 3.34866745262306 1.06106468541785 - - - hypothetical protein 251094 1.39712007880969 3.11283046409566 1.05669582863381 - - - hypothetical protein 251095 1.32652902795713 3.23409820005649 1.13335341021308 534 Na+-driven multidrug efflux pump V hypothetical protein 251096 1.29858115796945 2.96351318875599 1.00964315698093 524 Sugar kinases, ribokinase family G Fructokinase 251097 1.37750655135278 3.32178549522985 1.05909195188649 - - - hypothetical protein 251098 1.27720504795029 2.85582960921593 0.991160347146698 - - - hypothetical protein 251099 1.30231153195933 3.12558396180572 1.08207161729897 501 Zn-dependent protease with chaperone function O protease HTPX 251100 1.24117729389422 2.81502962492561 0.978982128600239 1131 ABC-type multidrug transport system, ATPase component V ABC transporter, ATP-binding protein 251101 1.29040233574351 3.16403445576968 1.09251379561723 1511 Predicted membrane protein S ABC transporter, permease protein 251102 1.32066997092263 3.29431533568592 1.08185533491668 1280 Putative threonine efflux protein E transporter, LysE family 251103 1.30127797020319 2.84499462479637 0.979980826852904 2109 ATP:corrinoid adenosyltransferase H Cob(I)alamin adenosyltransferase 251104 1.28041376205622 3.05657571486361 1.06584777509352 1970 Large-conductance mechanosensitive channel M Large-conductance mechanosensitive channel 251105 1.42950307905843 3.27090704243831 1.06350614453344 4635 Flavodoxin CH Flavodoxin 251106 1.31986455365942 2.92426684303635 1.00002400762233 4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases V type I restriction-modification system restriction subunit 251107 1.37353734619804 3.05611794952721 0.992839038333742 732 Restriction endonuclease S subunits V type I restriction-modification system specificity subunit 251108 1.38328473592504 2.98263438751195 1.01358859828259 - - - hypothetical protein 251109 1.2604101654863 2.92428520209037 1.02350857485832 1199 Rad3-related DNA helicases KL hypothetical protein 251110 1.23910564791218 2.72988402439736 0.979198529396021 - - - hypothetical protein 251111 1.32052086329065 2.79032846188988 0.976864869773745 - - - hypothetical protein 251112 1.30234690248587 2.90851397737155 1.00971849556218 286 Type I restriction-modification system methyltransferase subunit V type I restriction-modification system specificity subunit 251113 1.2813705630114 2.86644192511927 0.990918825823649 708 Exonuclease III L Exodeoxyribonuclease III 251114 1.23362727103516 2.75965826696363 0.991037125679241 662 Mannose-6-phosphate isomerase G hypothetical protein 251115 1.25758785553813 2.81989295325909 0.997409080901101 2520 Predicted methyltransferase R methyltransferase 251116 1.28021651019976 2.88928409778821 0.957575221960286 - - - hypothetical protein 251117 1.26403103669809 2.90438691942166 0.950382847465241 - - - hypothetical protein 251118 1.2643067595334 2.98913392773864 1.02176181459949 - - - hypothetical protein 251119 1.27598991161447 2.94755722253519 0.977903368033424 - - - hypothetical protein 251120 1.37454574233578 3.07017272434456 1.0315501013496 - - - hypothetical protein 251121 1.30314903745353 2.84393208376465 0.950289774706104 1453 Predicted oxidoreductases of the aldo/keto reductase family R oxidoreductase 251122 1.32572983906371 3.0686666726521 1.07201609314747 1680 Beta-lactamase class C and other penicillin binding proteins V putative 6-aminohexanoate-dimer hydrolase 251123 1.39770464104085 3.07182636970277 0.930627805524976 326 Molecular chaperone, HSP90 family O hypothetical protein 251124 1.37599364844471 3.1313453314311 0.899910160936007 - - - hypothetical protein 251125 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 251126 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 251127 1.50846415293732 3.3811162846975 1.05277290628241 - - - hypothetical protein 251128 1.30056156047231 2.80207713135171 0.99764179264198 - - - conserved protein 251129 1.33659785431867 3.04406307302012 1.02084477586137 - - - conserved protein 251130 1.47815954156701 3.19428213151685 0.892027388540801 - - - hypothetical protein 251131 1.40187860776158 3.04066744923377 0.978138163688 - - - hypothetical protein 251132 1.32821678182662 2.97879553480577 0.995638066614092 5421 Transposase L Transposase 251133 1.26772166893858 2.9662002418034 0.860655787911396 3291 FOG: PKD repeat R conserved protein 251134 1.3241108323262 3.03186017591971 0.920708387895812 3291 FOG: PKD repeat R hypothetical protein 251135 1.32323163956562 2.97023284517601 1.03316856182014 4978 Transcriptional regulator, effector-binding domain/component KT transcriptional regulator, MerR family 251136 1.24196709426821 3.08303095739451 1.024286409228 3391 Uncharacterized conserved protein S hypothetical protein 251137 1.3688477767808 3.18424548287518 1.09017005329308 - - - putative methyltransferase 251138 1.39214570824427 3.03847488597565 1.04158658472982 - - - transcriptional regulator, ArsR family 251139 1.25433014593486 2.905900052626 1.02224835272316 - - - hypothetical protein 251140 1.29808703496649 3.04389896617748 1.08635220762008 - - - hypothetical protein 251141 1.32914821307169 3.09382907393786 1.05835823407388 - - - hypothetical protein 251142 1.30750478543854 3.00452552483914 0.999053891270681 3379 Uncharacterized conserved protein S hypothetical protein 251143 1.26892916183823 3.04774734312278 1.05780593271512 3291 FOG: PKD repeat R hypothetical protein 251144 1.24881394224181 2.73517692063289 0.940512587178447 1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain S transcriptional regulator 251145 1.29989377012764 2.89266455113297 1.01855888649883 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I putative acetyl-CoA synthetase 251146 1.37693887439578 2.92638122711274 1.01433334669049 - - - ketoisovalerate oxidoreductase subunit 251147 1.27035865458873 2.94384548774839 0.98867087346862 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C ketoisovalerate oxidoreductase subunit 251148 1.27223071535115 2.93377297181411 1.03425126567405 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C ketoisovalerate oxidoreductase subunit 251149 1.44606112562388 3.21967665083965 1.01792503523832 - - - conserved protein 251150 1.30588560164105 2.8966907638903 1.01510111829718 19 Diaminopimelate decarboxylase E Ornithine decarboxylase 251151 1.37099527283421 3.42165080773031 1.16258894164002 531 Amino acid transporters E Transporter 251152 1.31723014514443 2.97119569867088 1.01216430882588 426 Uncharacterized flavoproteins C Flavodoxin 251153 1.25241734278762 2.81231012001016 0.910529502146121 174 Glutamine synthetase E Glutamine synthetase 251154 1.39285881529771 3.4255453744836 1.12340300528311 - - - Potassium channel protein 251155 1.27245443833243 2.9171576165082 1.03044079601125 1650 Uncharacterized protein conserved in archaea S hypothetical protein 251156 1.48283302258428 3.81066020868007 1.20212663395211 - - - hypothetical protein 251157 1.304584346691 3.04024695696108 1.04139904249776 - - - hypothetical membrane spanning protein 251158 1.43796964042563 3.11259839579244 1.01131975591143 - - - hypothetical membrane associated protein 251159 1.31212930933289 3.21080271299071 1.11229359133542 534 Na+-driven multidrug efflux pump V DinF protein 251160 1.29340155311593 2.79860253465588 0.938972869818465 1846 Transcriptional regulators K transcriptional regulator, MarR family 251161 1.25002178090013 3.05109356908809 1.09103705024688 4872 Predicted membrane protein S hypothetical protein 251162 1.29538892147517 3.12630759308411 1.09348210280902 4872 Predicted membrane protein S hypothetical protein 251163 1.34133129157591 3.10406045058056 1.07180470542791 1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E hypothetical protein 251164 1.32898186438174 3.2718682322152 1.13000045987789 5006 Predicted permease, DMT superfamily R Transporter 251165 1.31759137045643 2.78008352626632 0.76504251390847 - - - hypothetical protein 251166 1.30739454589755 2.91579940013839 1.01732713556632 518 GMP synthase - Glutamine amidotransferase domain F conserved protein 251167 1.30509662245668 3.08314820472831 1.09272609726975 2898 Uncharacterized conserved protein S conserved protein 251168 1.27918926398091 3.06273046116915 1.0891889160817 4870 Cysteine protease O hypothetical protein 251169 1.28252344054561 3.11943579956508 1.09669441283516 534 Na+-driven multidrug efflux pump V conserved protein 251170 1.31603421543497 3.02978607872633 1.08314525520117 642 Signal transduction histidine kinase T Two component system histidine kinase 251171 1.38939242882749 3.16544351095318 1.01834464006932 3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain KT Response regulator receiver domain 251172 1.28609815501847 2.96092961615963 1.05849719403854 826 Collagenase and related proteases O protease 251173 1.30589655106896 2.76411442189346 0.79093914745772 640 Predicted transcriptional regulators K transcriptional regulator, ArsR family 251174 1.47104828527236 3.5565509247594 1.12196737325701 679 Predicted permeases R Transporter 251175 1.35421396025054 3.43073021050416 1.10523999946336 - - - Cation efflux protein 251176 1.32829762713837 3.26633127440619 1.06685468207559 53 Predicted Co/Zn/Cd cation transporters P Cation efflux protein 251177 1.30836358938998 2.98616056660016 1.02127631584892 1892 Uncharacterized protein conserved in archaea S hypothetical protein 251178 1.27294002652393 2.88056440777754 1.01027857004183 1151 6Fe-6S prismane cluster-containing protein C Prismane protein 251179 1.28536618124462 2.89000436448472 0.963527086391237 - - - Ferredoxin 251180 1.30999084184139 2.55174992891394 0.91394759787548 - - - conserved protein 251181 1.33575500648305 3.18699744192936 1.0877167203526 2512 Uncharacterized membrane-associated protein/domain S conserved protein 251182 1.31904931991164 2.85393843117995 0.935839118101423 - - - conserved protein 251183 1.38949557600525 3.19973483291142 1.0394209752841 - - - conserved protein 251184 1.34069381169066 3.07890079947423 1.01264793749027 - - - conserved protein 251185 1.32597748845632 3.27164464632592 1.12024625004493 2244 Membrane protein involved in the export of O-antigen and teichoic acid R Transporter 251186 1.28947581445682 2.83377144301874 1.01151151136128 - - - conserved protein 251187 1.33050821503628 2.98396349555553 1.00847952829475 - - - conserved protein 251188 1.35848105053256 3.13562384038216 1.02871347743739 1131 ABC-type multidrug transport system, ATPase component V ABC transporter, ATP-binding protein 251189 1.29930629341845 3.24899722938135 1.10041823011229 - - - ABC transporter, permease protein 251190 1.3088660599338 3.12615642798692 1.06043405679323 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR putative ketoreductase 251191 1.30990021551193 2.93755270048965 0.993593433355591 1926 Predicted phosphoribosyltransferases R conserved protein 251192 1.34616894017358 2.99615780280726 1.09170063423303 1926 Predicted phosphoribosyltransferases R conserved protein 251193 1.45348972227049 3.15984342432437 0.97149382342748 - - - Transposase 251194 1.40576498481153 3.19189465294255 0.969671095132451 - - - Transposase 251195 1.32883494937847 3.45658593896971 1.1797785434293 306 Phosphate/sulphate permeases P Phosphate permease 251196 1.29766779649774 2.94817203027912 1.00946723185993 1392 Phosphate transport regulator (distant homolog of PhoU) P conserved protein 251197 1.43800493674667 3.67168842238543 1.11905946494061 - - - hypothetical protein 251198 1.29428514541232 2.80015359124773 0.926252891029601 1476 Predicted transcriptional regulators K HTH DNA-binding protein 251199 1.29462109806751 3.07760547943851 1.10374847963739 2145 Hydroxyethylthiazole kinase, sugar kinase family H Hydroxyethylthiazole kinase 251200 1.29476211399668 2.98749517365108 1.05071777166945 352 Thiamine monophosphate synthase H Thiamin-phosphate pyrophosphorylase 251201 1.53477318048534 3.54339869680952 0.981970884976987 3415 Transposase and inactivated derivatives L Transposase 251202 1.39001808706666 3.05788033932242 0.924465254486984 - - - Transposase 251203 1.38969995123815 3.50201170853453 1.14736429150396 3247 Uncharacterized conserved protein S conserved protein 251204 1.31793479189359 2.82567908817284 0.968093937529848 - - - hypothetical protein 251205 1.37843853798227 3.09530848358301 1.04043092631904 641 Arylsulfatase regulator (Fe-S oxidoreductase) R putative transcriptional regulator 251206 1.38058976638476 3.46115446901304 1.15406927832873 3247 Uncharacterized conserved protein S hypothetical protein 251207 1.39508780851031 3.25178366738099 1.00825908675139 - - - hypothetical protein 251208 1.45551662422873 3.59093271067874 1.1562348357147 - - - hypothetical protein 251209 1.32801215100136 2.8956665703805 0.856141592103795 - - - hypothetical protein 251210 1.33989315084899 2.86375899548181 0.884958021683048 3436 Transposase and inactivated derivatives L Transposase 251211 1.4977073585506 3.4718415129341 1.00848375404606 - - - Transposase 251212 1.34764668136921 3.00320159354977 0.90205567889788 1357 Uncharacterized low-complexity proteins S conserved protein 251213 1.46500240790008 3.27256220794128 0.91572875036144 - - - hypothetical protein 251214 1.37543858320069 3.10387394065423 1.00365592277192 1518 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 251215 1.44860297861283 3.20442537562916 0.96635666107685 - - - hypothetical protein 251216 1.31463302389486 2.87787657330769 0.959335378411033 - - - hypothetical protein 251217 1.35799128123436 2.96669091133742 0.962164696024788 - - - hypothetical protein 251218 1.28873168049961 2.84174093482771 0.927286009654313 417 DNA polymerase elongation subunit (family B) L hypothetical protein 251219 1.34092311663941 3.02239473588474 0.903054865813681 - - - hypothetical protein 251220 1.22767920836793 2.69012507906532 0.917843500627309 - - - hypothetical protein 251221 1.32499945673059 3.10149111536827 1.06498633981559 - - - hypothetical protein 251222 1.24767611139136 2.79539873182071 0.978981503527989 4741 Predicted secreted endonuclease distantly related to archaeal Holliday junction resolvase F conserved protein 251223 1.31725521802478 3.01182119054089 1.0587866142637 - - - hypothetical protein 251224 1.22557227835753 2.93715694784735 1.0343065696473 3264 Small-conductance mechanosensitive channel M conserved protein 251225 1.31847226777245 3.23632202229777 1.02685318441812 2323 Predicted membrane protein S hypothetical protein 251226 1.30085548854793 3.0858621569411 1.06971815077566 668 Small-conductance mechanosensitive channel M conserved protein 251227 1.32674069102821 3.24001312202307 1.11004360988545 1296 Predicted branched-chain amino acid permease (azaleucine resistance) E Branched-chain amino acid transport protein 251228 1.22895710770775 2.98343318493707 1.03421764703011 1687 Predicted branched-chain amino acid permeases (azaleucine resistance) E Branched-chain amino acid transport protein 251229 1.29817543723114 2.86158940266083 0.984374794618169 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C Coenzyme F420 hydrogenase beta subunit 251230 1.29140190534604 2.9722446919453 0.919696000775137 - - - Transposase 251231 1.31892233583589 3.10270051695547 1.02500479283833 - - - hypothetical protein 251232 1.27996871295865 3.13662533784236 1.08593357247728 - - - conserved protein 251233 1.36992259689522 3.13484451837283 1.0127067621794 778 Nitroreductase C NADPH-flavin oxidoreductase 251234 1.31162301949133 3.061328419413 1.04064702662622 1045 Serine acetyltransferase E Serine O-acetyltransferase 251235 1.37563296456158 2.9442447853743 0.998065121274949 4802 Ferredoxin-thioredoxin reductase, catalytic subunit C Ferredoxin-thioredoxin reductase, catalytic chain 251236 1.29813682521667 2.91558001978611 1.03497354125111 695 Glutaredoxin and related proteins O Glutaredoxin 251237 1.35076408778205 3.32954986814305 1.13258852025696 2814 Arabinose efflux permease G putative transport protein 251238 1.35072705471039 2.65070422627518 0.835502828165729 - - - conserved protein 251239 1.26839494482282 2.95640991960171 1.0046605538259 1253 Hemolysins and related proteins containing CBS domains R hypothetical protein 251240 1.31696005520382 3.13552782388297 1.10825443916289 1253 Hemolysins and related proteins containing CBS domains R conserved protein 251241 1.30824268872727 3.0100377985507 1.05752625415856 - - - hypothetical protein 251242 1.33232072341667 3.08406798782681 1.04022069158135 693 Putative intracellular protease/amidase R protease I 251243 1.31151416673507 3.28378029615172 1.13150893440203 1836 Predicted membrane protein S hypothetical membrane spanning protein 251244 1.30952744401042 2.98102961165566 1.05237380285747 1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and re C Dihydrolipoamide dehydrogenase 251245 1.32468012336538 3.13904866376339 1.06799078459112 3291 FOG: PKD repeat R conserved protein 251246 1.32701383071059 3.0692377942635 1.07680974136052 2520 Predicted methyltransferase R SAM-dependent methyltransferases 251247 1.34508054000481 2.95404942455964 0.991363004916624 1199 Rad3-related DNA helicases KL putative ATP-dependent helicase 251248 1.3039970478445 2.97658422592188 1.00021477111608 221 Inorganic pyrophosphatase C putative inorganic pyrophosphatase 251249 1.26827718841866 2.84985902338752 1.01133604649492 641 Arylsulfatase regulator (Fe-S oxidoreductase) R transcriptional regulator 251250 1.40452065490262 3.30274708150803 1.10873057408445 1408 Predicted phosphohydrolases R conserved protein 251251 1.21784220299907 2.56789060544769 0.917529179584716 - - - hypothetical protein 251252 1.4705291578194 3.56052069231383 0.962361559391953 - - - hypothetical protein 251253 1.35756905359292 3.13508310550755 1.03730513856033 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R conserved protein 251254 1.28871211389871 2.8464383663855 0.994239587944928 556 Helicase subunit of the DNA excision repair complex L Excinuclease ABC, subunit B 251255 1.29489095541788 2.83514951836102 1.00117941337837 322 Nuclease subunit of the excinuclease complex L Excinuclease ABC, subunit C 251256 1.30146284593801 2.9637824097168 1.0511516834969 178 Excinuclease ATPase subunit L Excinuclease ABC, subunit A 251257 1.3346511259814 3.09337936402327 1.04580466585926 1553 Uncharacterized conserved protein involved in intracellular sulfur reduction P hypothetical protein 251258 1.31936724733959 3.04272281297572 1.03129356253019 1600 Uncharacterized Fe-S protein C Iron-sulfur cluster-binding protein 251259 1.3583400874202 3.14742898875025 0.88476666826355 1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restri V hypothetical protein 251260 1.28621677058828 2.90551559296474 1.04132479697736 3920 Signal transduction histidine kinase T hypothetical sensory transduction histidine kinase 251261 1.28201444308169 2.64294924432946 1.00588895437274 - - - hypothetical protein 251262 1.33448803806179 3.06546082367301 1.07241827983636 334 Glutamate dehydrogenase/leucine dehydrogenase E glutamate dehydrogenase 251263 1.48827370618727 3.42792537900062 1.10373066377327 334 Glutamate dehydrogenase/leucine dehydrogenase E glutamate dehydrogenase 251264 1.32012717523939 3.14164420981544 1.08249446702449 644 Dehydrogenases (flavoproteins) C hypothetical protein 251265 1.31434763145784 2.95964172469449 1.05690817282568 5270 PUA domain (predicted RNA-binding domain) J Phosphoadenosine phosphosulfate reductase 251266 1.36364463942394 3.11462003017423 1.01328088913699 - - - hypothetical protein 251267 1.29475993887628 2.94364155934344 0.965146136180558 - - - hypothetical protein 251268 1.28774103876397 3.10907515941936 1.07160502843103 628 Predicted permease R hypothetical protein 251269 1.31345971655516 2.94296056916648 1.01762658095934 441 Threonyl-tRNA synthetase J Threonyl-tRNA synthetase 251270 1.33125820067841 2.94022886426756 1.04923827092465 1061 DNA or RNA helicases of superfamily II KL putative DNA or RNA helicase of superfamily II 251271 1.35565653221065 3.42952711099972 1.10559893688457 - - - conserved protein 251272 1.27720914847419 2.83726751628996 0.980280729341946 4740 Predicted metalloprotease R conserved protein 251273 1.34915513418778 2.95428946271696 0.976212664117576 - - - conserved protein 251274 1.35263390956815 3.04013763150973 1.01233664305643 778 Nitroreductase C Ferredoxin 251275 1.377289711278 3.18651941097289 1.05834774156683 4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K transcriptional regulator, AraC family 251276 1.25483515222385 2.72504766481551 0.942850568895087 3153 Predicted acetyltransferase R Acetyltransferase 251277 1.4236648267002 3.09201672564659 0.874434106176413 3183 Predicted restriction endonuclease V 5-methylcytosine-specific restriction enzyme A 251278 1.41526820763217 3.48308114988444 1.12374274074092 - - - hypothetical protein 251279 1.34329801913897 3.16323195495775 1.00106181487309 135 Phosphoribosylanthranilate isomerase E N-(5'-phosphoribosyl)anthranilate isomerase 251280 1.30904934842931 2.83413113565074 0.969035818684608 - - - hypothetical protein 251281 1.40127630483588 3.10614316073328 1.00986362521493 - - - hypothetical protein 251282 1.40852936285359 3.14906756951293 1.03985806636244 4119 Predicted NTP pyrophosphohydrolase LR hypothetical protein 251283 1.24444096980751 3.04651490469124 1.08769033170819 3420 Nitrous oxidase accessory protein P conserved protein 251284 1.3266704589632 3.29812827872266 1.14962467179074 2814 Arabinose efflux permease G Transport protein 251285 1.33960024785143 3.29824674890162 1.11343217166432 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Oligopeptide transporter, permease protein 251286 1.33020214000353 3.30953957522414 1.1290612212795 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP Oligopeptide transporter, permease protein 251287 1.25997755563399 2.88076194081993 1.00455930624607 747 ABC-type dipeptide transport system, periplasmic component E Oligopeptide-binding protein OppA 251288 1.29184824036137 2.98278464629686 1.04246418626525 4608 ABC-type oligopeptide transport system, ATPase component E Oligopeptide transporter, ATP-binding protein 251289 1.32563238252398 3.10775765049162 1.05998181710419 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP Oligopeptide transporter, ATP-binding protein 251290 1.28163170082688 3.24741494653137 1.1224059599102 1301 Na+/H+-dicarboxylate symporters C permease, Na+/H+-dicarboxylate symporter 251291 1.28473300741952 3.00270458942843 1.06165548305062 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase 251292 1.27018445063615 2.8338770259527 1.01381488677214 437 Fe-S-cluster-containing hydrogenase components 1 C Ferredoxin 251293 1.23795421405903 2.67223788073357 0.941351057045577 518 GMP synthase - Glutamine amidotransferase domain F conserved protein 251294 1.29672577867258 2.98621087093573 1.02744021278872 546 Predicted phosphatases R Phosphoglycolate phosphatase 251295 1.30246215829129 2.86399346573389 0.992638049697191 5010 Flp pilus assembly protein TadD, contains TPR repeats U O-linked N-acetylglucosamine transferase 251296 1.32909865361021 3.0513259092605 1.05539532725561 1233 Phytoene dehydrogenase and related proteins Q conserved protein 251297 1.39462316391155 3.09415483743626 1.0176643723837 2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases PR putative ferredoxin 251298 1.32643236484807 3.22635564871704 1.06651963804363 - - - hypothetical protein 251299 1.21959442349754 2.79506136826886 0.949405267899349 5012 Predicted cobalamin binding protein R Monomethylamine corrinoid protein 251300 1.28284097366289 2.84409238740387 0.907430236483349 - - - Monomethylamine:corrinoid methyltransferase 251301 1.19928067639838 2.80888129153407 0.855554937320072 - - - Monomethylamine:corrinoid methyltransferase MtmB 251302 1.21758944231927 2.75778282446611 0.964810426930023 - - - conserved protein 251303 1.31887304270525 2.96469197682826 1.01951650500804 - - - hypothetical protein 251304 1.28503130163402 3.03947977295087 1.0475444625446 - - - hypothetical protein 251305 1.30276402209911 2.95273096788919 1.03432976237927 - - - hypothetical protein 251306 1.3049694571497 3.07096779772843 1.07973616824421 - - - conserved protein 251307 1.30663133902069 2.83024516481125 0.955239369517857 4783 Putative Zn-dependent protease, contains TPR repeats R conserved protein 251308 1.40576498481153 3.19189465294255 0.969671095132451 - - - Transposase 251309 1.45348972227049 3.15984342432437 0.97149382342748 - - - Transposase 251310 1.45233736218566 3.62797575743401 1.10119026144623 - - - hypothetical protein 251311 1.23804581641802 2.73684099893961 0.920950789764539 - - - hypothetical protein 251312 1.37276418210432 3.01376570515386 0.969124136206834 - - - conserved protein 251313 1.35469866506281 2.87220426445319 1.00602982458014 - - - hypothetical protein 251314 1.32283057600279 2.89537403531991 1.00560035470743 - - - hypothetical protein 251315 1.35987291970517 2.91265326174014 0.962345062960305 - - - hypothetical protein 251316 1.36718197067405 2.92836487377005 1.0906341118388 - - - hypothetical protein 251317 1.34354940370547 2.80628663340678 0.908881380027163 - - - hypothetical protein 251318 1.40876255008207 3.24685482093967 0.955461864827256 - - - conserved protein 251319 1.45238103865264 3.22322571820918 1.00062703697574 - - - hypothetical protein 251320 1.33935388311467 3.09207799129493 0.90674976329832 1336 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) L conserved protein 251321 1.37048012692169 3.08207982728089 0.930997710333834 - - - hypothetical protein 251322 1.32205408809743 2.95801093962507 0.937304814094812 1604 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) L hypothetical protein 251323 1.31910173866016 2.97263867276577 0.919434003367887 - - - hypothetical protein 251324 1.30638737226225 2.90172768578789 0.975607946235008 - - - conserved protein 251325 1.26730010965628 2.82716180777356 0.922517455890625 - - - hypothetical protein 251326 1.45755096803693 3.34271351606178 0.999369887776521 - - - hypothetical protein 251327 1.50130443362378 3.64533592070203 1.09776887312181 - - - hypothetical protein 251328 1.40138705377455 3.41521223740321 1.09309232490594 - - - hypothetical protein 251329 1.4307853259924 3.4369186075439 1.13577782398015 - - - hypothetical protein 251330 1.44360381926694 3.33328686663925 1.01703912694902 - - - hypothetical protein 251331 1.4070470789704 3.21857582323461 1.07243494407501 - - - hypothetical protein 251332 1.50511733328871 3.58558383983234 1.19134930190583 - - - hypothetical protein 251333 1.42046715269496 3.49251273949828 1.09129465133417 - - - hypothetical protein 251334 1.42271368819239 3.51783924085327 1.11378000030069 - - - hypothetical protein 251335 1.83398264787374 4.04884353834542 0.989509824935662 - - - hypothetical protein 251336 1.279137339655 2.79400743736666 0.949291351772718 - - - conserved protein