Troponin Elevation in the Elderly Patient With Hip Fracture - Full Text View

Sponsored by:	Sheba Medical Center
Information provided by:	Sheba Medical Center
ClinicalTrials.gov Identifier:	NCT00647309

Purpose

Elevated troponin is powerful and independent adverse prognostic marker in patient with ACS. However, non specific (non cardiac) troponin elevation is a common finding among hospitalized patients and worse prognosis too.

The aim of this study is examine the prevalence of incidental cardiac troponin rise in a group of patient aged 65 and over admitted to geriatric department with hip fracture, and influence of troponin elevation on outcomes like ACS, death, motor and cognitive function.

Condition
Hip Fracture

MedlinePlus related topics: Fractures Hip Injuries and Disorders Hip Replacement Rehabilitation

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Correlation Between Troponin Level and Rehabilitation Outcome in Elderly Patient With Hip Fracture

Further study details as provided by Sheba Medical Center:

Primary Outcome Measures:

all cause mortality, motor and cognitive function [ Time Frame: one year ] [ Designated as safety issue: No ]

Biospecimen Retention: Samples With DNA

Biospecimen Description:

whole blood

Estimated Enrollment:	100
Study Start Date:	April 2008
Estimated Study Completion Date:	February 2011
Estimated Primary Completion Date:	February 2010 (Final data collection date for primary outcome measure)

Groups/Cohorts
1
2

Detailed Description:

data collection will include epidemiological data (age, gender, living arrangement, basic functional status, fracture date, surgery date, surgery type, length of stay) as well as previous comorbidities. in addition, routine blood tests and baseline ECG will be recorded.

troponin levels will be studied within 24 hours from admission, and 24 hours following surgery. in case of elevated troponin levels, ECG will be repeated, and echocardiography together with a cardiologist evaluation will be carried out.

data regarding in-hospital complications, motor and cognitive function (by FIM scale) and lab will be recorded. after discharge. followup will be recorded every 3 months, up to 1 year period, recoding the above mentioned data.

Eligibility

Ages Eligible for Study:	65 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

patients aged 65 years and over with hip fracture

Criteria

Inclusion Criteria:

Age 65 and over with hip fracture

Exclusion Criteria:

None

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00647309

Locations

Israel
Sheba Medical Center, Geriatric Rehabilitation dept	Recruiting
Ramat Gan, Israel, 52621
Contact: Arad Marina, MD 973-3-5305108 aradm@post.tau.ac.il
Principal Investigator: arad marina, MD
Sub-Investigator: Adunsky Abraham, MD

Sponsors and Collaborators

Sheba Medical Center

Investigators

Principal Investigator:

Marina Arad, MD

Sheba Medical Center

More Information

Responsible Party:	Sheba Medical Center ( Marina Arad MD )
Study ID Numbers:	SHEBA-08-5096-MA-CTIL
Study First Received:	March 26, 2008
Last Updated:	October 22, 2008
ClinicalTrials.gov Identifier:	NCT00647309
Health Authority:	Israel: Israeli Health Ministry Pharmaceutical Administration

Study placed in the following topic categories:

Hip Fractures
Femoral Fractures
Fractures, Bone

Wounds and Injuries
Disorders of Environmental Origin
Leg Injuries

Additional relevant MeSH terms:

Hip Injuries

ClinicalTrials.gov processed this record on February 11, 2009