Chirgwin K, Feldman J, Augenbraun M, Landesman S, Minkoff H; National Conference on Human Retroviruses and Related Infections.
Program Abstr Second Natl Conf Hum Retrovir Relat Infect Natl Conf Hum Retrovir Relat Infect 2nd 1995 Wash DC. 1995 Jan 29-Feb 2; 151.
State University of New York, Brooklyn, NY.
Objective: To assess the relationship between venereal warts, HIV status and degree of immuno deficiency, adjusting for sexual risk behavior. Methods: 253 HIV-infected and 658 HIV-negative women were studied at 6 mo intervals regarding the presence of venereal warts, other lab-confirmed STDs, T- cells, and sexual behavior. Results: The incidence of venereal warts was significantly higher in HIV-infected women (age-adjusted incidence rate ratio 11.6, 95% CI 4.0- 37.8, p less than 0.001). This increased incidence persisted after adjusting for high-risk sexual behavior and other STDs. The incidence was increased even in HIV-infected women with only minimal immunodeficiency (CD4 greater than 500/mm3). Conclusion: The association between HPV-related disease and HIV may be due to common behavioral risk factors for acquisition or to HIV-related immunodeficiency. These data suggest that the association of venereal warts with HIV is due to a higher risk of progression to clinical disease rather than increased rates of acquisition. The increased risk of warts occurs early, preceding most other opportunistic infections.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Condylomata Acuminata
- Female
- HIV
- HIV Infections
- HIV Seronegativity
- HIV Seropositivity
- Humans
- Incidence
- Papillomaviridae
- Risk Factors
- Risk-Taking
- Sexual Behavior
- Sexually Transmitted Diseases
- immunology
Other ID:
UI: 102213503
From Meeting Abstracts