| Proc Natl Acad Sci U S A. 1970 November; 67(3): 1390–1397. | PMCID: PMC283364 |
Influence of Mercuric Ions on the Phosphorescence and Photochemistry of DNA *R. O. Rahn, M. D. C. Battista, and L. C. Landry BIOLOGY DIVISION, OAK RIDGE NATIONAL LABORATORY, OAK RIDGE, TENNESSEE 37830 Abstract Partial mercuration of DNA, such that roughly one mercuric ion is bound for every two thymine residues, results in an enhancement of the phosphorescence by a factor of ten and a small enhancement of the photosteady thymine dimer yield. Complete mercuration of DNA [one Hg(II) added per momoner unit] results in quenching of the phosphorescence intensity and an inhibition of thymine dimer production. The enhancement of the phosphorescence is interpreted in terms of a heavy-atom effect caused by the preferential binding of Hg(II) to the thymine residues. The quenching of both the thymine phosphorescence and the rate of thymine dimerization upon complete mercuration is probably due to energy transfer from thymine to another base, presumably adenine, which when mercurated acts as an energy trap. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (891K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. These references are in PubMed. This may not be the complete list of references from this article. - KATZ, S. The reversible reaction of Hg (II) and double-stranded polynucleotides. A step-function theory and its significance. Biochim Biophys Acta. 1963 Feb 26;68:240–253. [PubMed]
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