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There are a total of 37 record(s) matching your query.
Sorted by: Date Added To NTRS in Descending order
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Experiment K305: Quantitative analysis of selected bone parameters. Supplement 1: Effects of weightlessness on osteoblast differentiation in rat molar periodontium
Author(s): Roberts, W. E.; Mozsary, P. G.; Morey-Holton, E.
Abstract: The morphometric analysis of periodontal ligament (PDL), the osteogenic interface between tooth and bone, is described. Immediately post-flight, PDL width and total cell number were decreased. Frequency distributions of ...
NASA Center: Ames Research Center
Publication Year: 1981
Added to NTRS: 2004-11-03
Accession Number: 81N32833; Document ID: 19810024290
Effects of Spaceflight on Bone: The Rat as an Animal Model for Human Bone Loss
Author(s): Halloran, B.; Weider, T.; Morey-Holton, E.
Abstract: The loss of weight bearing during spaceflight results in osteopenia in humans. Decrements in bone mineral reach 3-10 after as little as 75-184 days in space. Loss of bone mineral during flight decreases bone strength and ...
NASA Center: Ames Research Center
Publication Year: 1999
Added to NTRS: 2004-11-03
Document ID: 20000020526
The role of 1,25-dihydroxyvitamin D in the inhibition of bone formation induced by skeletal unloading
Author(s): Halloran, B. P.; Bikle, D. D.; Wronski, T. J.; GLOBUS. R.; Levens, M. J.; Morey-Holton, E.
Abstract: Skeletal unloading results in osteopenia. To examine the involvement of vitamin D in this process, the rear limbs of growing rats were unloaded and alterations in bone calcium and bone histology were related to changes in ...
NASA Center: Ames Research Center
Publication Year: 1983
Added to NTRS: 2004-11-03
Accession Number: 85N29522; Document ID: 19850021210; Report Number: NAS 1.15:87480, NASA-TM-87480
Bone loss during simulated weightlessness - Is it glucocorticoid mediated
Author(s): Bikle, D. D.; Halloran, B. P.; Cone, C. M.; Morey-Holton, E.
Abstract: Elevating the hindquarters of a rat by the tail unweights the hind limbs but maintains normal weight-bearing by the forelimbs. This maneuver leads to a decrease in bone mass and calcium content in the unweighted bones (e.g., ...
NASA Center: Ames Research Center
Publication Year: 1985
Added to NTRS: 2004-11-03
Accession Number: 86A30423; Document ID: 19860045685
Animal models for simulating weightlessness
Author(s): Morey-Holton, E.; Wronski, T. J.
Abstract: NASA has developed a rat model to simulate on earth some aspects of the weightlessness alterations experienced in space, i.e., unloading and fluid shifts. Comparison of data collected from space flight and from the head-down ...
NASA Center: Ames Research Center
Publication Year: 1982
Added to NTRS: 2004-11-03
Accession Number: 82A40749; Document ID: 19820057214
The salutary effect of dietary calcium on bone mass in a rat model of simulated weightlessness
Author(s): Bikle, D. D.; Globus, R.; Halloran, B. P.; Morey-Holton, E.
Abstract: Whether supplementation of dietary calcium reduces the differences in bone mass of unweighed limbs and normally weighted limbs, and whether parathyroid hormone (PTH) and 1,25-dihydroxyvitamin D (1,25(OH)2D) respond ...
NASA Center: Ames Research Center
Publication Year: 1985
Added to NTRS: 2004-11-03
Accession Number: 85N26073; Document ID: 19850017762
Experiment K305: Quantitative analysis of selected bone parameters
Author(s): Wrongski, T. J.; Morey-Holton, E.; Cann, C. E.; Arnaud, C. D.; Baylink, D. J.; Turner, R. T.; Jee, W. S. S.
Abstract: The skeletal alterations induced by space flight were determined to be a reduced rate of periosteal bone formation in tibial and humeral diaphyses, a decreased trabecular bone volume, and an increased fat content of the bone ...
NASA Center: Ames Research Center
Publication Year: 1981
Added to NTRS: 2004-11-03
Accession Number: 81N32832; Document ID: 19810024289
Skeletal Alterations in Rats During Space Flight
Author(s): Wronski, T. J.; Morey-Holton, E.; Jee, W. S. S.
Abstract: Male Wistar rats were placed in orbit for an 18.5 day period aboard the Soviet Cosmos 1129 biological satellite. The skeletal changes which occurred during space flight were a reduced rate of periosteal bone formation in the ...
NASA Center: Ames Research Center
Publication Year: 1981
Added to NTRS: 2004-11-03
Document ID: 19980211164; Report Number: NAS 1.15:207536, NASA/TM-1981-207536
Increased Renal Solute Excretion in Rats Following Space Flight
Author(s): Wade, Charles E.; Moore, A. L.; Morey-Holton, E.
Abstract: Following space flight a diuresis, due to an increase in free water clearance, has been suggested in humans. To assess the effects of space flight on renal function, rats were flown in space for 14 days. Rats were divided ...
NASA Center: Ames Research Center
Publication Year: 1995
Added to NTRS: 2004-11-03
Document ID: 20020024705
Effects of simulated weightlessness on bone mineral metabolism
Author(s): Globus, R. K.; Bikle, D. D.; Morey-Holton, E.
Abstract: It is pointed out that prolonged space flight, bedrest, and immobilization are three factors which can produce a negative calcium balance, osteopenia, and an inhibition of bone formation. It is not known whether the effects ...
NASA Center: Ames Research Center
Publication Year: 1984
Added to NTRS: 2004-11-03
Accession Number: 85A41325; Document ID: 19850059174
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