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Title The level of maternal methemoglobin during pregnancy in an air-polluted environment
Creator/Author Mohorovic, L. [Obstetrics& Gynaecology Primary Care, Labin (Croatia)]
Publication Date2003 Dec 01
OSTI IdentifierOSTI ID: 20436307
Other Number(s)ISSN 0091-6765; EVHPAZ ; TRN: 000300147
Resource TypeJournal Article
Resource RelationEnvironmental Health Perspectives ; VOL. 111 ; ISSUE: 16 ; PBD: Dec 2003
Subject01 COAL, LIGNITE, AND PEAT; 20 FOSSIL-FUELED POWER PLANTS ; FOSSIL-FUEL POWER PLANTS; COAL; WOMEN; PREGNANCY; BIOLOGICAL MARKERS; PRECURSOR; GLOBINS; AIR POLLUTION; CORRELATIONS; SULFUR DIOXIDE; CONCENTRATION RATIO; BLOOD; URINE; HEALTH HAZARDS
Description/Abstract The objective was to determine if a correlation could be established between the ground-level concentrations of sulfur dioxide and methemoglobin concentrations in pregnant women when a coal-powered thermoelectric power plant was in operation ('dirty' period) and when it was closed ('clean' period). The location of the power plant, Plomin 1, in Labin, Croatia, was taken into consideration. Blood and urine samples of each pregnant woman in the study were tested three times in the clean period (n= 138) and three times in the dirty period (n= 122), with 1 month between each test. A correlation was found between the increase in mean values of methemoglobin and the ground-level concentration of SO{sub 2} on corresponding dates during the dirty period (r= 0.72, p< 0.01). In the clean period, the negative mean value of methemoglobin was significant (r= -0.60, p{<=} 0.05), whereas in the dirty period, the positive mean value of methemoglobin was significant (r= 0.73, p{<=} 0.01). The increase of maternal methemoglobin could be a useful biomarker to determine when the health of pregnant women is threatened by toxic substances in the environment.
Country of PublicationUnited States
LanguageEnglish
Formatpage(s) 1902-1905
System Entry Date2004 Mar 22

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