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UGID:240424     UniGene Hs.445387     Homo sapiens (human)   RPS6KA3
Insulin-stimulated protein kinase 1 (ISPK-1) (RPS6KA3)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_683747.1 ribosomal protein S6 kinase polypeptide 3 M. musculus 100.0 739
NP_004577.1 ribosomal protein S6 kinase, 90kDa, polypeptide 3 H. sapiens 100.0 739
NP_001092407.1 ribosomal protein S6 kinase, 90kDa, polypeptide 3 B. taurus 100.0 739
XP_548888.2 PREDICTED: similar to ribosomal protein S6 kinase polypeptide 3 isoform 3 C. lupus familiaris 100.0 710
XP_001491765.2 PREDICTED: similar to ribosomal protein S6 kinase polypeptide 3 E. caballus 99.9 701
XP_001363055.1 PREDICTED: similar to ribosomal protein S6 kinase 2 M. domestica 99.6 739
XP_001513942.1 PREDICTED: similar to ribosomal protein S6 kinase polypeptide 3 O. anatinus 99.6 697
NP_001084222.1 Rsk-2 X. laevis 96.7 736
NP_997951.1 ribosomal protein S6 kinase polypeptide 3 D. rerio 93.7 731
NP_001021602.1 RSK-pNinety (RSK-p90 kinase) homolog family member (rskn-1) C. elegans 74.9 728
NP_523437.2 RPS6-protein kinase-II CG17596-PA D. melanogaster 72.3 762
NP_187484.1 ATPK19 (ARABIDOPSIS THALIANA PROTEIN KINASE 19); kinase A. thaliana 54.2 321
XP_330633.1 hypothetical protein N. crassa 53.4 429
XP_001693559.1 ribosomal protein S6 kinase C. reinhardtii 51.0 316
NP_015121.1 cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk3p; Tpk2p S. cerevisiae 45.7 328

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; mammary gland; intestine; bone; thyroid; mouth; pharynx; liver; uncharacterized tissue; lung; skin; prostate; ear; muscle; embryonic tissue; kidney; bone marrow; bladder; testis; placenta; eye; uterus; brain; pancreas; vascular; lymph node; stomach; connective tissue; esophagus; trachea; spleen; thymus; epididymis; cervix; ascites; ovary; blood; heart; adrenal gland; ganglia; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp22.2-p22.1
UniSTS entry: Chr X (n/a)
UniSTS entry: Chr Y D10S275
UniSTS entry: Chr X (n/a)
UniSTS entry: Chr X RH36312
UniSTS entry: Chr X A010B08
UniSTS entry: Chr X G33067
UniSTS entry: Chr X RH69875
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AB102662.1 Homo sapiens RPS6KA3 mRNA, partial cds P
NM_004586.2 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3), mRNA PA
AB208933.1 Homo sapiens mRNA for ribosomal protein S6 kinase, 90kDa, polypeptide 3 variant protein P
BC096301.1 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 3, mRNA (cDNA clone MGC:116978 IMAGE:40007452), complete cds P
BC096303.1 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 3, mRNA (cDNA clone MGC:116981 IMAGE:40007456), complete cds P
BC096302.3 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 3, mRNA (cDNA clone MGC:116979 IMAGE:40007453), complete cds P
AK022869.1 Homo sapiens cDNA FLJ12807 fis, clone NT2RP2002316
AK313932.1 Homo sapiens cDNA, FLJ94572, Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 3(RPS6KA3), mRNA P
AK294373.1 Homo sapiens cDNA FLJ56618 complete cds, highly similar to Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) P
AK296775.1 Homo sapiens cDNA FLJ56653 complete cds, highly similar to Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) P
BC015451.1 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 3, mRNA (cDNA clone IMAGE:4429357), with apparent retained intron PA
L07599.1 Homo sapiens ribosomal protein S6 kinase 3 (RPS6KA3) mRNA, partial cds P
U08316.1 Human insulin-stimulated protein kinase 1 (ISPK-1) mRNA, complete cds P

EST sequences (300)

AA906056.1 Clone IMAGE:1505579 mixed 3' read
AA906057.1 Clone IMAGE:1505581 mixed 3' read
R18031.1 Clone IMAGE:125028 mixed 5' read P
AI050776.1 Clone IMAGE:1664013 skin 3' read
BX108073.1 Clone IMAGp998C101163_;_IMAGE:488769 uterus A
CB157416.1 Clone L17N670205n1-9-C10 liver 5' read A
CB163538.1 Clone L17N670205n1-32-D10 liver 5' read P
CB108591.1 Clone L3SNU475-28-G01 liver 5' read
AI278229.1 Clone IMAGE:1879425 mixed 3' read
R33668.1 Clone IMAGE:136281 placenta 3' read
AI242997.1 Clone IMAGE:1848148 mixed 3' read A
AI309736.1 Clone IMAGE:1913801 kidney 3' read
AI344677.1 Clone IMAGE:1917568 kidney 3' read
AI368015.1 Clone IMAGE:1934946 mixed 3' read A
AI475476.1 Clone IMAGE:2149006 mixed 3' read A
AI623484.1 Clone IMAGE:2229046 pancreas 3' read
AI624766.1 Clone IMAGE:2231424 uterus 3' read
AI561193.1 Clone IMAGE:2211033 uterus 3' read
AF117656.1 Clone tianoc3-adr1.9 ovary A
R56992.1 Clone F0072 heart 5' read
AI761980.1 Clone IMAGE:2384187 kidney 3' read A
AL048274.1 Clone DKFZp586P1723 uterus
AI865235.1 Clone IMAGE:2411771 lymph node 3' read
Z19300.1 Clone 12C02 muscle
F00326.1 Clone B6H05 muscle
F01225.1 Clone B6H05 muscle P
CB957495.1 Clone IMAGE:30352709 mixed 5' read
CB990523.1 Clone IMAGE:30346616 placenta 5' read
CB992581.1 Clone IMAGE:30339845 placenta 5' read P
CB996662.1 Clone IMAGE:30335805 placenta 5' read P
AI955671.1 Clone IMAGE:2509606 pancreas 3' read A
AI969458.1 Clone IMAGE:2563099 skin 3' read PA
CD300712.1 Clone IMAGE:30375642 brain 5' read
BX474710.1 Clone DKFZp686M05171 muscle 5' read P
BX474748.1 Clone DKFZp686B22172 muscle 5' read P
AW023360.1 Clone IMAGE:2487356 ear 5' read
BX480089.1 Clone DKFZp686J09216 muscle 5' read P
BX485774.1 Clone DKFZp686I23248 muscle 5' read A
CD687677.1 pharynx P
CD702649.1 pharynx P
AW068580.1 Clone NHTBC_cn21c06 bone
AW068581.1 Clone NHTBC_cn21c06 bone P
AW070210.1 Clone IMAGE:2567816 mixed 3' read
AW073800.1 Clone IMAGE:2575210 mixed 3' read
CF124225.1 prostate 5' read
CF136261.1 Clone IMAGE:3091545 lymph node 5' read P
CF141302.1 Clone IMAGE:3098760 prostate 5' read P
AW167169.1 Clone IMAGE:2633823 uterus 3' read
CF593856.1 Clone IMAGE:30528897 placenta 5' read
AW298782.1 Clone IMAGE:2732642 uncharacterized tissue 3' read A
AW364152.1 kidney
AW364746.1 kidney P
AW377227.1 intestine P
AW377242.1 intestine P
AW377369.1 intestine P
AW380725.1 mouth
D12184.1 Clone s306 liver 3' read A
R74017.1 Clone IMAGE:156808 mammary gland 5' read
AW753193.1 intestine
AW772017.1 Clone IMAGE:3032758 kidney 3' read
BX951732.1 Clone DKFZp781E0815 uncharacterized tissue 5' read P
CK905714.1 Clone IMAGE:5636992 pancreas 3' read A
AW874118.1 Clone IMAGE:3126088 thyroid 3' read
AW945626.1 lung
AW945627.1 lung
AW951032.1 uncharacterized tissue
CN286124.1 embryonic tissue 5' read P
CN286125.1 embryonic tissue 5' read P
CN286126.1 embryonic tissue 5' read P
CN286127.1 embryonic tissue 5' read P
CN286128.1 embryonic tissue 5' read P
CN286129.1 embryonic tissue 5' read P
CN286130.1 embryonic tissue 5' read P
CN286131.1 embryonic tissue 5' read P
AW956844.1 uncharacterized tissue
AW960697.1 uncharacterized tissue
CN360234.1 embryonic tissue 5' read
CN360235.1 embryonic tissue 5' read
CN372448.1 embryonic tissue 5' read
BE080427.1 mammary gland
CR740391.1 Clone IMAGp998G015520_;_IMAGE:2231448 uterus 3' read A
BP239123.1 Clone HEP05786 liver 5' read P
BP241399.1 Clone HEP14725 liver 5' read P
BP242348.1 Clone HEP16892 liver 5' read P
BP243706.1 Clone HEP21215 liver 5' read P
BP243756.1 Clone HEP21342 liver 5' read P
BP236746.1 Clone HCR08386 vascular 5' read P
BP237065.1 Clone HCR09139 vascular 5' read P
BP341438.1 Clone STM02462 stomach 5' read P
BP255649.1 Clone HRC09570 kidney 5' read P
BP255692.1 Clone HRC09659 kidney 5' read P
BP258791.1 Clone HRT04578 heart 5' read P
BP265273.1 Clone JTH00420 thyroid 5' read P
BP293018.1 Clone LNG09967 lung 5' read P
BP383198.1 Clone kaia3117 intestine 5' read P
CV317972.1 placenta
CV572755.1 Clone od28d02 eye 5' read
CV574698.1 Clone oe27f03 eye 5' read
AW600242.1 lung 5' read
AW600243.1 lung 5' read
BE501621.1 Clone IMAGE:3151189 skin 3' read
BE502112.1 Clone IMAGE:3151060 skin 3' read
H37993.1 Clone IMAGE:191626 mixed 5' read P
H38216.1 Clone IMAGE:191626 mixed 3' read
BE550377.1 Clone IMAGE:3219509 uncharacterized tissue 3' read
AV655344.1 Clone GLCEFD09 liver 3' read P
BP389314.1 Clone hbt11161 pancreas 3' read
BE766392.1 brain
AV684171.1 Clone GKCCKF01 liver 5' read
AV690707.1 Clone GKCCJA03 liver 5' read
AV692140.1 Clone GKCCFC08 liver 5' read
BE873831.1 Clone IMAGE:3886461 lung 5' read
DN998658.1 Clone TC111006 bone marrow 5' read P
BE892200.1 Clone IMAGE:3920334 skin 5' read
R95841.1 Clone IMAGE:199198 mixed 3' read
AV706801.1 Clone ADBDRG07 adrenal gland 5' read P
BF028703.1 Clone IMAGE:3996010 bladder 5' read P
BF037623.1 Clone IMAGE:3864721 ovary 5' read A
BF106112.1 Clone IMAGE:4042958 lung 5' read P
CR989571.1 Clone RZPDp9017B1239 uncharacterized tissue 5' read P
CT001432.1 Clone RZPDp9016D1712 uncharacterized tissue 5' read P
CT002007.1 Clone RZPDp9016L1431 uncharacterized tissue 5' read P
AU127899.1 Clone NT2RP2002316 testis 5' read
H53111.1 Clone IMAGE:202467 mixed 3' read
H53217.1 Clone IMAGE:202467 mixed 5' read
BF210725.1 Clone IMAGE:4097353 bone marrow 5' read
BF240449.1 Clone IMAGE:4099633 bone marrow 5' read P
T29607.1 lung 5' read P
H55921.1 Clone IMAGE:204148 mixed 3' read
H60202.1 Clone IMAGE:207615 mixed 3' read
H60249.1 Clone IMAGE:207615 mixed 5' read
H61901.1 Clone IMAGE:204148 mixed 5' read P
BF671064.1 Clone IMAGE:4291965 muscle 5' read
H66157.1 Clone IMAGE:234009 mixed 3' read
DA278059.1 Clone BRCOC2005524 brain 5' read
BF691895.1 Clone IMAGE:4333460 skin 5' read
H67666.1 Clone IMAGE:211202 mixed 3' read
BF694445.1 Clone IMAGE:4246085 muscle 5' read
DA686961.1 Clone NT2NE2005324 5' read P
DA620221.1 Clone JCMLC2001602 uncharacterized tissue 5' read P
DA538252.1 Clone FEKID2001028 kidney 5' read P
BF858054.1 prostate P
DA656310.1 Clone MESAN2011948 kidney 5' read P
DA592743.1 Clone HLUNG2015263 lung 5' read P
DA548473.1 Clone HCASM2006821 vascular 5' read P
DA674881.1 Clone NETRP2005723 blood 5' read P
DA597095.1 Clone HSYRA2001372 connective tissue 5' read P
AU141308.2 Clone THYRO1000375 thyroid 5' read P
DA531594.1 Clone FEBRA2024914 brain 5' read P
AU150294.1 Clone NT2RP2002316 testis 3' read A
DA759141.1 Clone NT2RP8007376 testis 5' read P
DA994625.1 Clone SYNOV4007494 connective tissue 5' read
DA811977.1 Clone OVARC1000454 ovary 5' read
DA997390.1 Clone T1ESE2001268 uncharacterized tissue 5' read
DA997666.1 Clone T1ESE2001647 uncharacterized tissue 5' read P
DA886180.1 Clone PUAEN2006457 vascular 5' read P
DA931725.1 Clone SPLEN2000789 spleen 5' read
DB016659.1 Clone TESOP2006025 esophagus 5' read P
DA746684.1 Clone NT2RP7011756 testis 5' read P
DA747664.1 Clone NT2RP7012877 testis 5' read
DA865964.1 Clone PROST2000482 prostate 5' read P
BF477754.1 Clone IMAGE:3676988 prostate 3' read A
H79716.1 Clone IMAGE:240213 mixed 5' read P
H79717.1 Clone IMAGE:240213 mixed 3' read
H80153.1 Clone IMAGE:233532 mixed 3' read
BF573892.1 Clone IMAGE:4271233 muscle 5' read
BF575732.1 Clone IMAGE:4290660 muscle 5' read
H81503.1 Clone IMAGE:230619 mixed 5' read P
H81773.1 Clone IMAGE:249262 skin 5' read
H81774.1 Clone IMAGE:249262 skin 3' read
BF790725.1 Clone IMAGE:4338230 muscle 5' read
DB263280.1 Clone UTERU2021614 uterus 5' read
DB381877.1 Clone THYRO1000375 thyroid 3' read
DB225352.1 Clone TRACH3017209 trachea 5' read P
DB163504.1 Clone THYMU3044837 thymus 5' read
BF743971.1 mammary gland
BF744284.1 mammary gland
BF745779.1 mammary gland
DB371246.1 Clone OVARC1000454 ovary 3' read
DB103608.1 Clone THYMU2003412 thymus 5' read
BF770869.1 epididymis
DW411712.1 liver
BG033625.1 Clone IMAGE:4403412 mammary gland 5' read P
H95748.1 Clone IMAGE:243039 mixed 5' read
BF994372.1 placenta P
BF965602.1 Clone IMAGE:4364562 bone 5' read
BF901416.1 blood P
BG166919.1 Clone IMAGE:4447156 kidney 5' read
BG179530.1 Clone IMAGE:4429357 prostate 5' read P
DB523354.1 Clone H013079H02 testis 3' read
N25223.1 Clone IMAGE:270209 skin 3' read
BG283507.1 Clone IMAGE:4520088 prostate 5' read
N39400.1 Clone IMAGE:270209 skin 5' read
D79840.1 Clone GEN-336C07 vascular 5' read
BG484167.1 Clone IMAGE:4617908 lung 5' read
BG498334.1 Clone IMAGE:4666418 prostate 5' read A
D30964.1 lung 5' read
BG537955.1 Clone IMAGE:4688217 lung 5' read
D31173.1 lung 5' read
D31252.1 lung 5' read
N52371.1 Clone IMAGE:246042 mixed 3' read
BG213093.1 connective tissue P
BG680701.1 Clone IMAGE:4751876 skin 5' read P
BG775542.1 Clone IMAGE:4761421 prostate 5' read P
BG775815.1 Clone IMAGE:4761421 prostate 3' read
BI091953.1 Clone IMAGE:4998272 placenta 5' read P
N76084.1 Clone IMAGE:295446 mixed 3' read
BJ989813.1 Clone hkmt-0393 liver 5' read P
BJ989814.1 Clone hkmt-0393 liver 3' read
BI255416.1 Clone IMAGE:5122872 cervix 5' read
AL597277.1 Clone DKFZp313C0912 uncharacterized tissue 5' read
AL599191.1 Clone DKFZp313P2324 uncharacterized tissue 5' read
DC359827.1 Clone HSYRA2005342 connective tissue 5' read P
DC378457.1 Clone PEBLM2004262 blood 5' read P
DC308670.1 Clone BRACE3026280 brain 5' read P
DC364877.1 Clone NB9N42001114 uncharacterized tissue 5' read P
DC424616.1 Clone PLACE1005988 placenta 5' read
DC427394.1 Clone PLACE1005988 placenta 3' read
DC418988.1 Clone TRACH3037374 trachea 5' read P
DC400936.1 Clone TESTI4011274 testis 5' read P
DC417118.1 Clone TRACH3019209 trachea 5' read P
DC410324.1 Clone THYMU3038037 thymus 5' read
DC391617.1 Clone SPLEN2036751 spleen 5' read P
DC390576.1 Clone SPLEN2023459 spleen 5' read P
DC368810.1 Clone NT2RI2025872 5' read P
DC403239.1 Clone TESTI4037866 testis 5' read P
DC415447.1 Clone TRACH3001846 trachea 5' read
DC372286.1 Clone NT2RP8003059 testis 5' read P
DC346096.1 Clone CTONG2010306 mouth 5' read P
DC357434.1 Clone HHDPC2000633 skin 5' read P
DC346356.1 Clone CTONG2014175 mouth 5' read P
DC317473.1 Clone BRAMY3007835 brain 5' read P
DC316310.1 Clone BRAMY2041080 brain 5' read P
BI820949.1 Clone IMAGE:5175310 mixed 5' read
W00439.1 Clone IMAGE:291178 skin 5' read
BI869651.1 Clone IMAGE:5403266 liver 5' read
BI857074.1 Clone IMAGE:5392453 mammary gland 5' read P
BI857169.1 Clone IMAGE:5392577 mammary gland 5' read
BM008007.1 Clone IMAGE:5451058 spleen 5' read P
BM014472.1 Clone IMAGE:5416355 mammary gland 5' read
BM511977.1 Clone IMAGE:5636992 pancreas 3' read A
BM512217.1 Clone IMAGE:5636992 pancreas 5' read
BM542179.1 Clone IMAGE:5539806 skin 5' read A
BM667935.1 Clone UI-E-DW0-agm-d-01-0-UI eye 3' read A
BM697290.1 Clone UI-E-DW0-agm-d-01-0-UI eye 5' read P
BM749137.1 Clone S11SNU1-5-A07 ascites 5' read P
BM753520.1 Clone S10SNU1-15-G02 ascites 5' read P
BM768599.1 Clone S14K402-9-A06 stomach 5' read A
BM787166.1 Clone S11SNU1-20-H08 ascites 5' read P
BM821568.1 Clone S20T665307-12-H10 stomach 5' read
BM833607.1 Clone S20T665307-47-C04 stomach 5' read
BM834578.1 Clone S11SNU1-68-C02 ascites 5' read P
BM834712.1 Clone S20T665307-44-H04 stomach 5' read
BM837850.1 Clone S9SNU601-76-C01 ascites 5' read
BG487432.1 pharynx 3' read A
BQ082753.1 Clone S14K402-57-A07 stomach 5' read
BQ277561.1 Clone IMAGE:5810903 mixed 5' read P
BQ345250.1 brain P
BQ356808.1 thyroid
BQ427696.1 Clone IMAGE:6156546 uterus 5' read
BQ719759.1 Clone IMAGE:6184757 ganglia 5' read P
AA045847.1 Clone IMAGE:488769 uterus 3' read A
AA046164.1 Clone IMAGE:488769 uterus 5' read
BU155630.1 Clone IMAGE:6164638 skin 5' read
BU188572.1 Clone IMAGE:6147519 skin 5' read P
C16055.1 Clone 202E08 vascular 5' read
C06096.1 Clone hbc5523 pancreas A
BU608357.1 Clone UI-CF-FN0-aew-l-16-0-UI lung 3' read A
BU623612.1 Clone UI-H-FG1-bgg-p-05-0-UI bone 3' read A
BU620678.1 Clone UI-H-FL1-bfx-m-12-0-UI bone 3' read A
BU618685.1 Clone UI-H-FH1-bfk-h-19-0-UI bone 3' read A
BU679117.1 Clone UI-CF-DU1-abd-i-06-0-UI lung 3' read A
AA300361.1 testis 5' read
D12009.1 Clone s141 liver
AA312007.1 blood 5' read
AA314380.1 intestine 5' read P
AA317826.1 eye 5' read
T70588.1 Clone IMAGE:108334 mixed 3' read
T70852.1 Clone IMAGE:108334 mixed 5' read P
AA348592.1 brain 3' read
AA348593.1 brain 5' read
CA843287.1 Clone IMAGE:6548539 pancreas 3' read A
AA366787.1 pancreas 5' read
T79934.1 Clone IMAGE:114989 mixed 3' read
AA383923.1 thyroid 5' read
CA942825.1 Clone IMAGE:6607193 pancreas 5' read
AA448668.1 Clone IMAGE:786086 embryonic tissue 3' read
T87455.1 Clone IMAGE:114989 mixed 5' read P
AA491466.1 Clone IMAGE:839794 eye 3' read
AA470521.1 Clone IMAGE:772079 prostate
AA574022.1 Clone IMAGE:916651 prostate
AA578676.1 Clone IMAGE:1028341 intestine 3' read
AA640167.1 Clone IMAGE:1117648 prostate 3' read A
AA677160.1 Clone IMAGE:454299 mixed 3' read
AA719391.1 Clone 1292776 testis 3' read
AA721569.1 Clone IMAGE:1235297 uncharacterized tissue
AA771907.1 Clone 1359137 parathyroid 3' read A
AA777547.1 Clone IMAGE:448424 mixed 3' read A
AA827987.1 Clone IMAGE:1420702 intestine 3' read
AA858312.1 Clone IMAGE:1323553 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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