National Toxicology Program

Selected information from two of the National Library of Medicine's databases: ChemIDPlus¹ and HSDB².

Names (NTP)

• DEHP
• Di(2-ethylhexyl) phthalate
• 1,2-BENZENEDICARBOXYLIC ACID, BIS (2-ETHYLHEXYL)ESTER (9CI)
• 1,2-BENZENEDICARBOXYLIC ACID, BIS(2-ETHYLHEXYL)ESTER (9CI)
• DEHP
• DI (2-ETHYLHEXYL) PHTHALATE (TRANSGENIC MODEL EVALUATION)
• Transgenic model evaluation (Di(2-ethylhexyl) phthalate)

Structure

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Chemical Properties²

Property	Description
Color/Form	Colorless, oily liquid.
Odor	SLIGHT ODOR Slight odor. Odorless
Taste	None found
Boiling Point	230 DEG C @ 5 MM HG
Melting Point	-55 deg C
Molecular Weight	390.56
Corrosivity	None found
Critical Temperature & Pressure	None found
Density/Specific Gravity	0.9861 @ 20 DEG C/20 DEG C
Disassociation Constants	None found
Heat of Combustion	-15,130 BTU/LB= -8410 CAL/G= -352X10+5 JOULES/KG
Heat of Vaporization	None found
log P (octanol-water)	log Kow= 7.60
pH	None found
Solubilities	LESS THAN 0.01% IN WATER @ 25 DEG C Soluble in blood and fluids containing lipoproteins MISCIBLE WITH MINERAL OIL & HEXANE In water, 0.285 mg/l at 24 deg C. Slightly soluble in carbon tetrachloride.
Spectral Properties	INDEX OF REFRACTION: 1.4836 @ 20 DEG C/D Intense mass spectral peaks: 149 m/z (100%), 57 m/z (32%), 167 m/z (29%), 71 m/z (21%) IR: 2526 (Coblentz Society Spectral Collection) NMR: 9392 (Sadtler Research Laboratories Spectral Collection) MASS: 2-708 (Archives of Mass Spectral Data, John Wiley & Sons, New York)
Surface Tension	LIQUID SURFACE TENSION: EST 15 DYNES/CM= 0.015 N/M @ 20 DEG C LIQUID-WATER INTERFACIAL TENSION: EST 30 DYNES/CM= 0.03 N/M @ 20 DEG C.
Vapor Density	16.0 (air=1)
Vapor Pressure	7.23X10-8 mm Hg at 25 deg C /from experimentally-derived coefficients/
Relative Evaporation Rate	None found
Viscosity	81.4 CENTIPOISES @ 20 DEG C
Other Properties	POUR POINT: -46 DEG C; 8.20 LB/GAL @ 20 DEG C 1 PPM= APPROX 15.94 MG/CU M 4.3 Relative dielectric constant (@ 60 Hz, 100 deg C); 0.5% Dissipation factor (@ 60 Hz, 100 deg C); 42 kV dielectric strength (ASTM D 877); 25 ul/min Gas absorption coefficient (ASTM D 2300) Vapor pressure = 9.75X10-6 mm Hg @ 25 deg C

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Uses²

• For Bis(2-ethylhexylphthalate) (USEPA/OPP Pesticide Code: 295200) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./
  
• The active ingredient is no longer contained in any registered pesticide products ... "cancelled."
  
• ... IN PLASTICIZING A VARIETY OF POLYMERIC MATERIALS: NATURAL RUBBER, SYNTHETIC RUBBER ... CELLULOSE ACETATE BUTYRATE, ETHYL CELLULOSE, NITROCELLULOSE, POLYMETHYL METHACRYLATE, POLYVINYL BUTYRAL, POLYSTYRENE, & POLYVINYLIDINE CHLORIDE.
  
• Plasticizer manufacture; plastics manufacture & recycling, processing; organic pump fluid
  
• PLASTICIZER FOR POLYVINYL CHLORIDE RESINS **PEER REVIEWED**
  
• PLASTICIZER FOR VINYL CHLORIDE COPOLYMER RESINS **PEER REVIEWED**
  
• PLASTICIZER FOR OTHER RESINS & SYNTHETIC RUBBERS **PEER REVIEWED**
  
• COMPONENT OF DIELECTRIC FLUIDS IN ELECTRICAL CAPACITATORS **PEER REVIEWED**
  
• SOLVENT-EG, FOR ERASABLE INK **PEER REVIEWED**
  
• ACARICIDE FOR USE IN ORCHARDS **PEER REVIEWED**
  
• INERT INGREDIENT IN PESTICIDE FORMULATIONS **PEER REVIEWED**
  
• VACUUM PUMP OIL **PEER REVIEWED**
  
• TESTING AGENT FOR AIR FILTRATION SYSTEMS **PEER REVIEWED**
  
• Plasticizer for ... chlorinated rubber
  
• Used widely in insect repellant formulations, cosmetics, rubbing alcohol, liquid soap, detergents, decorative inks, lacquers, munitions, industrial and lubricating oils, defoaming agents during paper and paperboard manufactures, and as pesticide carriers. /Phthalic Esters/
  
• Photographic film, wire and cable, adhesives
  
• As plasticizer in flexible vinyl products. As a replacement for PCBs in dielectric fluids for elctric capacitors.
  
• Plasticizer (polyvinyl chloride, rubber, adhesives, PVA emulsion paints, lacquers); non-reactive epoxy resin diluent.
  
• Plasticizer; also used as an insulating fluid in electrical transformers and pressure-sensitive printing.
  

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Superlist Classes¹

• ATSDR Profile Priority List, rank : 76
  
• Overall Carcinogenic Evaluation: Group 3
  
• Reasonably anticipated to be a carcinogen
  
• Reportable Quantity (RQ) = 100 lb
  
• TWA 5 mg/m3; Confirmed animal carcinogen with unknown relevance to humans
  
• TWA 5 mg/m3
  

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Notes (Sources: NTP,HSDB,RTECS,MESH)¹

• None found

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Other Registry Numbers¹

• 126639-29-0
  
• 137718-37-7
  
• 205180-59-2
  
• 40120-69-2
  
• 50885-87-5
  
• 8033-53-2
  
• 275818-89-8
  
• 109630-52-6
  
• 607374-50-5
  

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Synonyms (Sources: NTP, HSDB,RTECS,MESH)¹

• 4-09-00-03181 (Beilstein Handbook Reference)
• AI3-04273
• Bis(2-ethylhexyl) 1,2-benzenedicarboxylate
• Bisoflex 81
• Bisoflex DOP
• BRN 1890696
• Compound 889
• DEHP
• Di(2-ethylhexyl) orthophthalate
• Di(2-ethylhexyl) phthalate
• Di(2-ethylhexyl)orthophthalate
• Di(2-ethylhexyl)phthalate
• Dioctyl phthalate
• Ergoplast FDO
• Ergoplast FDO-S
• Ethylhexyl phthalate
• Eviplast 80
• Eviplast 81
• Fleximel
• Flexol DOP
• Flexol Plasticizer DOP
• Good-rite GP 264
• Hatcol DOP
• Hercoflex 260
• HSDB 339
• Jayflex DOP
• Kodaflex DOP
• Mollan O
• NCI-C52733
• Nuoplaz DOP
• Octoil
• Palatinol AH
• Pittsburgh PX-138
• Platinol AH
• Platinol DOP
• RC Plasticizer DOP
• RCRA waste number U028
• Reomol D 79P
• Reomol DOP
• Sicol 150
• Staflex DOP
• Truflex DOP
• Vestinol AH
• Vinicizer 80
• Witcizer 312

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Links to Additional Information¹

• PubMed Cancer
• CCRIS
• DART
• EINECS
• EMIC
• GENETOX
• Haz-Map
• Household Products
• HSDB
• IRIS
• ITER
• PubMed
• MeSH Heading
• MeSH
• PubMed Toxicology
• TOXLINE
• TOXMAP
• TRI2000
• TRI2001
• TRI2002
• TRI2003
• TRI2004
• TRI95
• TRI96
• TRI97
• TRI98
• TRI99
• WebWISER
• PubChem
• TRI2005

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Footnotes

¹ Source: the National Library of Medicine's ChemIDPlus, 10/28/2007.

² Source: the National Library of Medicine's Hazardous Substance Database, 10/28/2007.