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Our Science – Merino Website

Maria J. Merino, M.D.

Selected Publications

1)  Toro JR, Wei M, Glenn GM, Weinreich M, Toure O, Vocke C, Turner M, Choyke P, Merino MJ, Pinto PA, Steinberg SM, Schmidt LS, Linehan WM.
BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dube syndrome: a new series of 50 families and a review of published reports.
J. Med. Genet. 45: 321-31, 2008.
[Journal]
2)  Baloch ZW, LiVolsi VA, Asa SL, Rosai J, Merino MJ, Randolph G, Vielh P, DeMay RM, Sidawy MK, Frable WJ.
Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science Conference.
Diagn. Cytopathol. 36: 425-37, 2008.
[Journal]
3)  Gril B, Palmieri D, Bronder JL, Herring JM, Vega-Valle E, Feigenbaum L, Liewehr DJ, Steinberg SM, Merino MJ, Rubin SD, Steeg PS.
Effect of Lapatinib on the Outgrowth of Metastatic Breast Cancer Cells to the Brain.
J. Natl. Cancer Inst. 2008.
[Journal]
4)  Nickerson ML, Jaeger E, Shi Y, Durocher JA, Mahurkar S, Zaridze D, Matveev V, Janout V, Kollarova H, Bencko V, Navratilova M, Szeszenia-Dabrowska N, Mates D, Mukeria A, Holcatova I, Schmidt LS, Toro JR, Karami S, Hung R, Gerard GF, Linehan WM, Merino M, Zbar B, Boffetta P, Brennan P, Rothman N, Chow WH, Waldman FM, Moore LE.
Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors.
Clin. Cancer Res. 14: 4726-34, 2008.
[Journal]
5)  Layfield LJ, Abrams J, Cochand-Priollet B, Evans D, Gharib H, Greenspan F, Henry M, LiVolsi V, Merino M, Michael CW, Wang H, Wells SA.
Post-thyroid FNA testing and treatment options: a synopsis of the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference.
Diagn. Cytopathol. 36: 442-8, 2008.
[Journal]
6)  Mutter GL, Bergeron C, Deligdisch L, Ferenczy A, Glant M, Merino M, Williams AR, Blithe DL.
The spectrum of endometrial pathology induced by progesterone receptor modulators.
Mod. Pathol. 21: 591-8, 2008.
[Journal]
7)  Yang Y, Padilla-Nash HM, Vira MA, Abu-Asab MS, Val D, Worrell R, Tsokos M, Merino MJ, Pavlovich CP, Ried T, Linehan WM, Vocke CD.
The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dube gene pathway.
Cancer Genet. Cytogenet. 180: 100-9, 2008.
[Journal]
8)  Signoretti S, Bratslavsky G, Waldman FM, Reuter VE, Haaga J, Merino M, Thomas GV, Pins MR, Libermann T, Gillespie J, Tomaszewski JE, Compton CC, Hruszkewycz A, Linehan WM, Atkins MB.
Tissue-based research in kidney cancer: current challenges and future directions.
Clin. Cancer Res. 14: 3699-705, 2008.
[Journal]
9)  Huang H, Abraham J, Hung E, Averbuch S, Merino M, Steinberg SM, Pacak K, Fojo T.
Treatment of malignant pheochromocytoma/paraganglioma with cyclophosphamide, vincristine, and dacarbazine: recommendation From a 22-Year Follow-up of 18 Patients.
Cancer. 2008.
[Journal]
10)  Filie AC, Asa SL, Geisinger KR, Logani S, Merino M, Nikiforov YE, Clark DP.
Utilization of ancillary studies in thyroid fine needle aspirates: a synopsis of the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference.
Diagn. Cytopathol. 36: 438-41, 2008.
[Journal]
11)  Mai PL, Korde L, Kramer J, Peters J, Mueller CM, Pfeiffer S, Stratakis CA, Pinto PA, Bratslavsky G, Merino M, Choyke P, Linehan WM, Greene MH.
A possible new syndrome with growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case report.
Journal of medical case reports. 1: 9, 2007.
[Journal]
12)  Begnami MD, Quezado M, Pinto P, Linehan WM, Merino M.
Adenoid cystic/basal cell carcinoma of the prostate: review and update.
Arch. Pathol. Lab. Med. 131: 637-40, 2007.
[Journal]
13)  Powell DJ, Felipe-Silva A, Merino MJ, Ahmadzadeh M, Allen T, Levy C, White DE, Mavroukakis S, Kreitman RJ, Rosenberg SA, Pastan I.
Administration of a CD25-directed immunotoxin, LMB-2, to patients with metastatic melanoma induces a selective partial reduction in regulatory T cells in vivo.
J. Immunol. 179: 4919-28, 2007.
[Journal]
14)  Zbar B, Glenn G, Merino M, Middelton L, Peterson J, Toro J, Coleman J, Pinto P, Schmidt LS, Choyke P, Linehan WM.
Familial renal carcinoma: clinical evaluation, clinical subtypes and risk of renal carcinoma development.
J. Urol. 177: 461-5; discussion 465, 2007.
[Journal]
15)  Grubb RL, Franks ME, Toro J, Middelton L, Choyke L, Fowler S, Torres-Cabala C, Glenn GM, Choyke P, Merino MJ, Zbar B, Pinto PA, Srinivasan R, Coleman JA, Linehan WM.
Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer.
J. Urol. 177: 2074-9; discussion 2079-80, 2007.
[Journal]
16)  Rodriguez-Canales J, Hanson JC, Tangrea MA, Erickson HS, Albert PS, Wallis BS, Richardson AM, Pinto PA, Linehan WM, Gillespie JW, Merino MJ, Libutti SK, Woodson KG, Emmert-Buck MR, Chuaqui RF.
Identification of a unique epigenetic sub-microenvironment in prostate cancer.
J. Pathol. 211: 410-9, 2007.
[Journal]
17)  Linehan WM, Pinto PA, Srinivasan R, Merino M, Choyke P, Choyke L, Coleman J, Toro J, Glenn G, Vocke C, Zbar B, Schmidt LS, Bottaro D, Neckers L.
Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics.
Clin. Cancer Res. 13: 671s-679s, 2007.
[Journal]
18)  Horak CE, Mendoza A, Vega-Valle E, Albaugh M, Graff-Cherry C, McDermott WG, Hua E, Merino MJ, Steinberg SM, Khanna C, Steeg PS.
Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2.
Cancer Res. 67: 11751-9, 2007.
[Journal]
19)  Palau MA, Thu Pham T, Barnard N, Merino MJ.
Primary synovial sarcoma of the kidney with rhabdoid features.
Int. J. Surg. Pathol. 15: 421-8, 2007.
[Journal]
20)  Merino MJ, Torres-Cabala C, Pinto P, Linehan WM.
The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome.
Am. J. Surg. Pathol. 31: 1578-85, 2007.
[Journal]
21)  Stegmann BJ, Sinaii N, Liu S, Segars J, Merino M, Nieman LK, Stratton P.
Using location, color, size, and depth to characterize and identify endometriosis lesions in a cohort of 133 women.
Fertil Steril. 2007.
[Journal]
22)  Palmieri D, Bouadis A, Ronchetti R, Merino MJ, Steeg PS.
Rab11a dfferentially modulates epidermal growth factor-induced proliferation and motility in immortal breast cells.
Breast Cancer Res Treat. 2006.
In Press. [Journal]
23)  Remon C, Quiros PL, Perez Banasco V, Toran D, Tejuca F, Merino MJ, Guerrero J, Ruiz A, Paez MC, Martinez E, Espigares MJ, Gonzalez L, Martin G, Castro P, Fernandez E.
[Report of the Andalusian registry of patients with end stage renal disease in treatment with peritoneal dialysis: period 1999-2004].
Nefrologia. 26: 45-55, 2006.
[Journal]
24)  Palau MA, Merino MJ, Quezado M.
Corticotropin-producing pulmonary gangliocytic paraganglioma associated with Cushing's syndrome.
Hum. Pathol. 37: 623-6, 2006.
[Journal]
25)  Castillo M, Sanjuán A, Pérez N, Zanón G, Bons N, Vilanova M, Vanrell JA, Merino MJ, Fernández PL.
Fibrous Histiocytoma-like Spindle-Cell Proliferation in the Nipple After Body-Piercing.
Int. J. Surg. Pathol. 14: 89-93, 2006.
[Journal]
26)  Schinstine M, Filie AC, Torres-Cabala C, Abati A, Linehan WM, Merino M.
Fine-needle aspiration of a Xp11.2 translocation/TFE3 fusion renal cell carcinoma metastatic to the lung: report of a case and review of the literature.
Diagn. Cytopathol. 34: 751-6, 2006.
[Journal]
27)  Torres-Cabala C, Bibbo M, Panizo-Santos A, Barazi H, Krutzsch H, Roberts DD, Merino MJ.
Proteomic identification of new biomarkers and application in thyroid cytology.
Acta Cytol. 50: 518-28, 2006.
[Journal]
28)  Bakalov VK, Anasti JN, Calis KA, Vanderhoof VH, Premkumar A, Chen S, Furmaniak J, Smith BR, Merino MJ, Nelson LM.
Autoimmune oophoritis as a mechanism of follicular dysfunction in women with 46,XX spontaneous premature ovarian failure.
Fertil. Steril. 84: 958-65, 2005.
[Journal]
29)  Pavlovich CP, Grubb RL, Hurley K, Glenn GM, Toro J, Schmidt LS, Torres-Cabala C, Merino MJ, Zbar B, Choyke P, Walther MM, Linehan WM.
Evaluation and management of renal tumors in the Birt-Hogg-Dube syndrome.
J Urol. 173: 1482-6, 2005.
[Journal]
30)  Schmidt LS, Nickerson ML, Warren MB, Glenn GM, Toro JR, Merino MJ, Turner ML, Choyke PL, Sharma N, Peterson J, Morrison P, Maher ER, Walther MM, Zbar B, Linehan WM.
Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dube syndrome.
Am J Hum Genet. 76: 1023-33, 2005.
[Journal]
31)  Isaacs JS, Jung YJ, Mole DR, Lee S, Torres-Cabala C, Chung YL, Merino M, Trepel J, Zbar B, Toro J, Ratcliffe PJ, Linehan WM, Neckers L.
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability.
Cancer Cell. 8: 143-53, 2005.
[Journal]
32)  Vocke CD, Yang Y, Pavlovich CP, Schmidt LS, Nickerson ML, Torres-Cabala CA, Merino MJ, Walther MM, Zbar B, Linehan WM.
High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dube-associated renal tumors.
J Natl Cancer Inst. 97: 931-5, 2005.
[Journal]
33)  Beaty MW, Quezado M, Sobel ME, Duray P, Merino MJ.
Loss of heterozygosity on chromosome 1 and 9 and hormone receptor analysis of metastatic malignant melanoma presenting in breast.
Int J Surg Pathol. 13: 9-18, 2005.
[Journal]
34)  Palmieri D, Halverson DO, Ouatas T, Horak CE, Salerno M, Johnson J, Figg WD, Hollingshead M, Hursting S, Berrigan D, Steinberg SM, Merino MJ, Steeg PS.
Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer.
J Natl Cancer Inst. 97: 632-42, 2005.
[Journal]
35)  Wei MH, Toure O, Glenn GM, Pithukpakorn M, Neckers L, Stolle C, Choyke P, Grubb R, Middelton L, Turner ML, Walther MM, Merino MJ, Zbar B, Linehan WM, Toro JR.
Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer.
J Med Genet. 2005.
[Journal]
36)  Li-Ning-T E, Ronchetti R, Torres-Cabala C, Merino MJ.
Role of chromogenic in situ hybridization (CISH) in the evaluation of HER2 status in breast carcinoma: comparison with immunohistochemistry and FISH.
Int. J. Surg. Pathol. 13: 343-51, 2005.
[Journal]
37)  Lebowitz PF, Eng-Wong J, Swain SM, Berman A, Merino MJ, Chow CK, Venzon D, Zia F, Danforth D, Liu E, Zujewski J.
A phase II trial of neoadjuvant docetaxel and capecitabine for locally advanced breast cancer.
Clin Cancer Res. 10: 6764-9, 2004.
[Journal]
38)  Potlog-Nahari C, Feldman AL, Stratton P, Koziol DE, Segars J, Merino MJ, Nieman LK.
CD10 immunohistochemical staining enhances the histological detection of endometriosis.
Fertil Steril. 82: 86-92, 2004.
[Journal]
39)  Schmidt LS, Nickerson ML, Angeloni D, Glenn GM, Walther MM, Albert PS, Warren MB, Choyke PL, Torres-Cabala CA, Merino MJ, Brunet J, Bérez V, Borràs J, Sesia G, Middelton L, Phillips JL, Stolle C, Zbar B, Pautler SE, Linehan WM.
Early onset hereditary papillary renal carcinoma: germline missense mutations in the tyrosine kinase domain of the met proto-oncogene.
J Urol. 172: 1256-61, 2004.
[Journal]
40)  Killian JK, Merino M, Bondy C, Bakalov V, Chow C.
MRI of angiolipoma of the breast in Turner's syndrome.
AJR. American journal of roentgenology. 183: 1843-4, 2004.
[Journal]
41)  Killian JK, Merino M, Bondy C, Bakalov V, Chow C.
MRI of angiolipoma of the breast in Turner's syndrome.
AJR. American journal of roentgenology. 183: 1843-4, 2004.
[Journal]
42)  Bertheau P, Steinberg SM, Cowan K, Merino MJ.
Breast cancer in young women: clinicopathologic correlation.
Semin Diagn Pathol. 16: 248-56, 1999.
[Journal]
43)  Bertheau P, Steinberg SM, Cowan K, Merino MJ.
Breast cancer in young women: clinicopathologic correlation.
Semin Diagn Pathol. 16: 248-56, 1999.
[Journal]
44)  Zambrano NR, Lubensky IA, Merino MJ, Linehan WM, Walther MM.
Histopathology and molecular genetics of renal tumors toward unification of a classification system.
J. Urol. 162: 1246-58, 1999.
[Journal]
45)  Zambrano NR, Lubensky IA, Merino MJ, Linehan WM, Walther MM.
Histopathology and molecular genetics of renal tumors toward unification of a classification system.
J. Urol. 162: 1246-58, 1999.
[Journal]
46)  Sanz-Ortega J, Bryant B, Sanz-Esponera J, Asenjo JA, Saez MC, Torres A, Balibrea JL, Sobel ME, Merino MJ.
LOH at the APC/MCC gene (5Q21) is frequent in early stages of non-small cell lung cancer.
Pathol. Res. Pract. 195: 677-80, 1999.
[Journal]
47)  Sanz-Ortega J, Bryant B, Sanz-Esponera J, Asenjo JA, Saez MC, Torres A, Balibrea JL, Sobel ME, Merino MJ.
LOH at the APC/MCC gene (5Q21) is frequent in early stages of non-small cell lung cancer.
Pathol. Res. Pract. 195: 677-80, 1999.
[Journal]
48)  Gnant MF, Berger AC, Huang J, Puhlmann M, Wu PC, Merino MJ, Bartlett DL, Alexander HR, Libutti SK.
Sensitization of tumor necrosis factor alpha-resistant human melanoma by tumor-specific in vivo transfer of the gene encoding endothelial monocyte-activating polypeptide II using recombinant vaccinia virus.
Cancer Res. 59: 4668-74, 1999.
[Journal]
49)  Gnant MF, Berger AC, Huang J, Puhlmann M, Wu PC, Merino MJ, Bartlett DL, Alexander HR, Libutti SK.
Sensitization of tumor necrosis factor alpha-resistant human melanoma by tumor-specific in vivo transfer of the gene encoding endothelial monocyte-activating polypeptide II using recombinant vaccinia virus.
Cancer Res. 59: 4668-74, 1999.
[Journal]
50)  Zujewski J, Pai L, Wakefield L, Giusti R, Dorr FA, Flanders C, Caruso R, Kaiser M, Goodman L, Merino M, Gossard M, Noone MA, Denicoff A, Venzon D, Cowan KH, O'Shaughnessy JA.
Tamoxifen and fenretinide in women with metastatic breast cancer.
Breast Cancer Res. Treat. 57: 277-83, 1999.
[Journal]
51)  Zujewski J, Pai L, Wakefield L, Giusti R, Dorr FA, Flanders C, Caruso R, Kaiser M, Goodman L, Merino M, Gossard M, Noone MA, Denicoff A, Venzon D, Cowan KH, O'Shaughnessy JA.
Tamoxifen and fenretinide in women with metastatic breast cancer.
Breast Cancer Res. Treat. 57: 277-83, 1999.
[Journal]
52)  Krebs PA, Albuquerque A, Quezado M, Bryant B, Sobel ME, Merino MJ, Otis CN.
The use of microsatellite instability in the distinction between synchronous endometrial and colonic adenocarcinomas.
Int. J. Gynecol. Pathol. 18: 320-4, 1999.
[Journal]
53)  Krebs PA, Albuquerque A, Quezado M, Bryant B, Sobel ME, Merino MJ, Otis CN.
The use of microsatellite instability in the distinction between synchronous endometrial and colonic adenocarcinomas.
Int. J. Gynecol. Pathol. 18: 320-4, 1999.
[Journal]
54)  Maiman M, Watts DH, Andersen J, Clax P, Merino M, Kendall MA.
Vaginal 5-fluorouracil for high-grade cervical dysplasia in human immunodeficiency virus infection: a randomized trial.
Obstetrics and gynecology. 94: 954-61, 1999.
[Journal]
55)  Maiman M, Watts DH, Andersen J, Clax P, Merino M, Kendall MA.
Vaginal 5-fluorouracil for high-grade cervical dysplasia in human immunodeficiency virus infection: a randomized trial.
Obstetrics and gynecology. 94: 954-61, 1999.
[Journal]
56)  Sanjuan X, Bryant BR, Sobel ME, Merino MI.
Clonality Analysis of Benign Parathyroid Lesions by Human Androgen Receptor (HUMARA) Gene Assay.
Endocr. Pathol. 9: 293-300, 1998.
[Journal]
57)  Sanjuan X, Bryant BR, Sobel ME, Merino MI.
Clonality Analysis of Benign Parathyroid Lesions by Human Androgen Receptor (HUMARA) Gene Assay.
Endocr. Pathol. 9: 293-300, 1998.
[Journal]
58)  Bates SE, Bakke S, Kang M, Robey RW, Zhai S, Thambi P, Chen CC, Patil S, Smith T, Steinberg SM, Merino M, Goldspiel B, Meadows B, Stein WD, Choyke P, Balis F, Figg WD, Fojo T.
A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma.
Clin Cancer Res. 10: 4724-33, 2004.
[Journal]
59)  Torres-Cabala C, Panizo-Santos A, Krutzsch HC, Barazi H, Namba M, Sakaguchi M, Roberts DD, Merino MJ.
Differential expression of S100C in thyroid lesions.
Int J Surg Pathol. 12: 107-15, 2004.
[Journal]
60)  Warren MB, Torres-Cabala CA, Turner ML, Merino MJ, Matrosova VY, Nickerson ML, Ma W, Linehan WM, Zbar B, Schmidt LS.
Expression of Birt-Hogg-Dube gene mRNA in normal and neoplastic human tissues.
Mod Pathol. 17: 998-1011, 2004.
[Journal]
61)  Linehan WM, Vasselli J, Srinivasan R, Walther MM, Merino M, Choyke P, Vocke C, Schmidt L, Isaacs JS, Glenn G, Toro J, Zbar B, Bottaro D, Neckers L.
Genetic basis of cancer of the kidney: disease-specific approaches to therapy.
Clin Cancer Res. 10: 6282S-9S, 2004.
[Journal]
62)  Ronnett BM, Kajdacsy-Balla A, Gilks CB, Merino MJ, Silva E, Werness BA, Young RH.
Mucinous borderline ovarian tumors: points of general agreement and persistent controversies regarding nomenclature, diagnostic criteria, and behavior.
Hum Pathol. 35: 949-60, 2004.
[Journal]
63)  Sanz-Ortega J, Hernández S, Saez MC, Sierra E, Sanz-Ortega G, Torres A, Balibrea JL, Sanz-Esponera J, Merino MJ.
3p21, 5q21, 9p21 and 17p13.1 allelic deletions are potential markers of individuals with a high risk of developing adenocarcinoma in Barrett's epithelium without dysplasia.
Hepatogastroenterology. 50: 404-7, 2003.
[Journal]
64)  Stratton P, Winkel C, Premkumar A, Chow C, Wilson J, Hearns-Stokes R, Heo S, Merino M, Nieman LK.
Diagnostic accuracy of laparoscopy, magnetic resonance imaging, and histopathologic examination for the detection of endometriosis.
Fertil Steril. 79: 1078-85, 2003.
[Journal]
65)  Toro JR, Glenn G, Hou L, Duray P, Clark B, Merino M, Zbar B, Linehan M, Turner ML.
Facial papules, spontaneous pneumothorax, and renal tumors.
J Am Acad Dermatol. 48: 111-4, 2003.
[Journal]
66)  Palacios J, Sarrió D, García-Macias MC, Bryant B, Sobel ME, Merino MJ.
Frequent E-cadherin gene inactivation by loss of heterozygosity in pleomorphic lobular carcinoma of the breast.
Mod Pathol. 16: 674-8, 2003.
[Journal]
67)  Gourgiotis L, Sarlis NJ, Reynolds JC, VanWaes C, Merino MJ, Pacak K.
Localization of medullary thyroid carcinoma metastasis in a multiple endocrine neoplasia type 2A patient by 6-[18F]-fluorodopamine positron emission tomography.
J Clin Endocrinol Metab. 88: 637-41, 2003.
[Journal]
68)  Toro JR, Nickerson ML, Wei MH, Warren MB, Glenn GM, Turner ML, Stewart L, Duray P, Tourre O, Sharma N, Choyke P, Stratton P, Merino M, Walther MM, Linehan WM, Schmidt LS, Zbar B.
Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America.
Am J Hum Genet. 73: 95-106, 2003.
[Journal]
69)  Toro JR, Nickerson ML, Wei MH, Warren MB, Glenn GM, Turner ML, Stewart L, Duray P, Tourre O, Sharma N, Choyke P, Stratton P, Merino M, Walther MM, Linehan WM, Schmidt LS, Zbar B.
Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America.
Am J Hum Genet. 73: 95-106, 2003.
[Journal]
70)  Vasselli JR, Shih JH, Iyengar SR, Maranchie J, Riss J, Worrell R, Torres-Cabala C, Tabios R, Mariotti A, Stearman R, Merino M, Walther MM, Simon R, Klausner RD, Linehan WM.
Predicting survival in patients with metastatic kidney cancer by gene-expression profiling in the primary tumor.
Proc Natl Acad Sci U S A. 100: 6958-63, 2003.
[Journal]
71)  Vasselli JR, Shih JH, Iyengar SR, Maranchie J, Riss J, Worrell R, Torres-Cabala C, Tabios R, Mariotti A, Stearman R, Merino M, Walther MM, Simon R, Klausner RD, Linehan WM.
Predicting survival in patients with metastatic kidney cancer by gene-expression profiling in the primary tumor.
Proc Natl Acad Sci U S A. 100: 6958-63, 2003.
[Journal]
72)  Danforth DN, Cowan K, Altemus R, Merino M, Chow C, Berman A, Chaudhry U, Shriver C, Steinberg SM, Zujewski J.
Preoperative FLAC/granulocyte-colony-stimulating factor chemotherapy for stage II breast cancer: a prospective randomized trial.
Ann Surg Oncol. 10: 635-44, 2003.
[Journal]
73)  Yang JC, Sherry RM, Steinberg SM, Topalian SL, Schwartzentruber DJ, Hwu P, Seipp CA, Rogers-Freezer L, Morton KE, White DE, Liewehr DJ, Merino MJ, Rosenberg SA.
Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer.
J Clin Oncol. 21: 3127-32, 2003.
[Journal]
74)  Pak H, Gourgiotis L, Chang WI, Guthrie LC, Skarulis MC, Reynolds JC, Merino MJ, Schrump DS, Libutti SK, Alexander HR, Sarlis NJ.
Role of metastasectomy in the management of thyroid carcinoma: the NIH experience.
J Surg Oncol. 82: 10-8, 2003.
[Journal]
75)  Collins MT, Sarlis NJ, Merino MJ, Monroe J, Crawford SE, Krakoff JA, Guthrie LC, Bonat S, Robey PG, Shenker A.
Thyroid carcinoma in the McCune-Albright syndrome: contributory role of activating Gs alpha mutations.
J Clin Endocrinol Metab. 88: 4413-7, 2003.
[Journal]
76)  Abraham J, Bakke S, Rutt A, Meadows B, Merino M, Alexander R, Schrump D, Bartlett D, Choyke P, Robey R, Hung E, Steinberg SM, Bates S, Fojo T.
A phase II trial of combination chemotherapy and surgical resection for the treatment of metastatic adrenocortical carcinoma: continuous infusion doxorubicin, vincristine, and etoposide with daily mitotane as a P-glycoprotein antagonist.
Cancer. 94: 2333-43, 2002.
[Journal]
77)  Gillespie JW, Best CJ, Bichsel VE, Cole KA, Greenhut SF, Hewitt SM, Ahram M, Gathright YB, Merino MJ, Strausberg RL, Epstein JI, Hamilton SR, Gannot G, Baibakova GV, Calvert VS, Flaig MJ, Chuaqui RF, Herring JC, Pfeifer J, Petricoin EF, Linehan WM, Duray PH, Bova GS, Emmert-Buck MR.
Evaluation of non-formalin tissue fixation for molecular profiling studies.
Am J Pathol. 160: 449-57, 2002.
[Journal]
78)  Yu J, Steiner FA, Muench JP, Gourgiotis L, Skarulis MC, Altemus RM, Libutti SK, Merino MJ, Sarlis NJ.
Juxtathyroidal neck soft tissue angiosarcoma presenting as an undifferentiated thyroid carcinoma.
Thyroid. 12: 427-32, 2002.
[Journal]
79)  Stratton P, Winkel CA, Sinaii N, Merino MJ, Zimmer C, Nieman LK.
Location, color, size, depth, and volume may predict endometriosis in lesions resected at surgery.
Fertil Steril. 78: 743-9, 2002.
[Journal]
80)  Otis CN, Krebs PA, Albuquerque A, Quezado MM, San Juan X, Sobel ME, Merino MJ.
Loss of heterozygosity of p53, BRCA1, VHL, and estrogen receptor genes in breast carcinoma: correlation with related protein products and morphologic features.
Int J Surg Pathol. 10: 237-45, 2002.
[Journal]
81)  McCarthy NJ, Yang X, Linnoila IR, Merino MJ, Hewitt SM, Parr AL, Paik S, Steinberg SM, Hartmann DP, Mourali N, Levine PH, Swain SM.
Microvessel density, expression of estrogen receptor alpha, MIB-1, p53, and c-erbB-2 in inflammatory breast cancer.
Clin Cancer Res. 8: 3857-62, 2002.
[Journal]
82)  Nickerson ML, Warren MB, Toro JR, Matrosova V, Glenn G, Turner ML, Duray P, Merino M, Choyke P, Pavlovich CP, Sharma N, Walther M, Munroe D, Hill R, Maher E, Greenberg C, Lerman MI, Linehan WM, Zbar B, Schmidt LS.
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome.
Cancer Cell. 2: 157-64, 2002.
[Journal]
83)  Wulfkuhle JD, Sgroi DC, Krutzsch H, McLean K, McGarvey K, Knowlton M, Chen S, Shu H, Sahin A, Kurek R, Wallwiener D, Merino MJ, Petricoin EF, Zhao Y, Steeg PS.
Proteomics of human breast ductal carcinoma in situ.
Cancer Res. 62: 6740-9, 2002.
[Journal]
84)  Pavlovich CP, Walther MM, Eyler RA, Hewitt SM, Zbar B, Linehan WM, Merino MJ.
Renal tumors in the Birt-Hogg-Dube syndrome.
Am J Surg Pathol. 26: 1542-52, 2002.
[Journal]
85)  Zbar B, Alvord WG, Glenn G, Turner M, Pavlovich CP, Schmidt L, Walther M, Choyke P, Weirich G, Hewitt SM, Duray P, Gabril F, Greenberg C, Merino MJ, Toro J, Linehan WM.
Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dube syndrome.
Cancer Epidemiol Biomarkers Prev. 11: 393-400, 2002.
[Journal]
86)  Gourgiotis L, Al-Zubaidi N, Skarulis MC, Papanicolaou DA, Libutti SK, Alexander HR, Merino MJ, Sarlis NJ.
Successful outcome after surgical management in two cases of the.
Endocr Pract. 8: 259-65, 2002.
[Journal]
87)  Danforth DN, Aloj L, Carrasquillo JA, Bacharach SL, Chow C, Zujewski J, Whatley M, Galen B, Merino M, Neumann RD.
The role of 18F-FDG-PET in the local/regional evaluation of women with breast cancer.
Breast Cancer Res Treat. 75: 135-46, 2002.
[Journal]
88)  Sanz-Ortega J, Saez MC, Sierra E, Torres A, Balibrea JL, Hernando F, Sanz-Esponera J, Merino MJ.
3p21, 5q21, and 9p21 allelic deletions are frequently found in normal bronchial cells adjacent to non-small-cell lung cancer, while they are unusual in patients with no evidence of malignancy.
J Pathol. 195: 429-34, 2001.
[Journal]
89)  Bates S, Kang M, Meadows B, Bakke S, Choyke P, Merino M, Goldspiel B, Chico I, Smith T, Chen C, Robey R, Bergan R, Figg WD, Fojo T.
A Phase I study of infusional vinblastine in combination with the P-glycoprotein antagonist PSC 833 (valspodar).
Cancer. 92: 1577-90, 2001.
[Journal]
90)  Schmidt LS, Warren MB, Nickerson ML, Weirich G, Matrosova V, Toro JR, Turner ML, Duray P, Merino M, Hewitt S, Pavlovich CP, Glenn G, Greenberg CR, Linehan WM, Zbar B.
Birt-Hogg-Dube syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2.
Am J Hum Genet. 69: 876-82, 2001.
[Journal]
91)  Simsir A, Palacios D, Linehan WM, Merino MJ, Abati A.
Detection of loss of heterozygosity at chromosome 3p25-26 in primary and metastatic ovarian clear-cell carcinoma: utilization of microdissection and polymerase chain reaction in archival tissues.
Diagn Cytopathol. 24: 328-32, 2001.
[Journal]
92)  Lawrence JA, Adamson PC, Caruso R, Chow C, Kleiner D, Murphy RF, Venzon DJ, Shovlin M, Noone M, Merino M, Cowan KH, Kaiser M, O'Shaughnessy J, Zujewski J.
Phase I clinical trial of alitretinoin and tamoxifen in breast cancer patients: toxicity, pharmacokinetic, and biomarker evaluations.
J Clin Oncol. 19: 2754-63, 2001.
[Journal]
93)  Chico I, Kang MH, Bergan R, Abraham J, Bakke S, Meadows B, Rutt A, Robey R, Choyke P, Merino M, Goldspiel B, Smith T, Steinberg S, Figg WD, Fojo T, Bates S.
Phase I study of infusional paclitaxel in combination with the P-glycoprotein antagonist PSC 833.
J Clin Oncol. 19: 832-42, 2001.
[Journal]
94)  Lei JY, Middleton LP, Guo XD, Duray PH, McWilliams G, Linehan WM, Merino MJ.
Pigmented renal clear cell carcinoma with melanocytic differentiation.
Hum Pathol. 32: 233-6, 2001.
[Journal]
95)  Smallridge RC, Castro MR, Morris JC, Young PR, Reynolds JC, Merino MJ, Sarlis NJ.
Renal metastases from thyroid papillary carcinoma: study of sodium iodide symporter expression.
Thyroid. 11: 795-804, 2001.
[Journal]
96)  Rodrigues RG, Panizo-Santos A, Cashel JA, Krutzsch HC, Merino MJ, Roberts DD.
Semenogelins are ectopically expressed in small cell lung carcinoma.
Clin Cancer Res. 7: 854-60, 2001.
[Journal]
97)  Stratton P, Hartog B, Hajizadeh N, Piquion J, Sutherland D, Merino M, Lee YJ, Nieman LK.
A single mid-follicular dose of CDB-2914, a new antiprogestin, inhibits folliculogenesis and endometrial differentiation in normally cycling women.
Hum Reprod. 15: 1092-9, 2000.
[Journal]
98)  Sanjuan X, Sobel ME, Yang J, Merino MJ.
Alveolar soft part sarcoma: the role of prognostic markers.
Ann Diagn Pathol. 4: 135-42, 2000.
[Journal]
99)  Sanz-Ortega J, Steinberg SM, Moro E, Saez M, Lopez JA, Sierra E, Sanz-Esponera J, Merino MJ.
Comparative study of tumor angiogenesis and immunohistochemistry for p53, c-ErbB2, c-myc and EGFr as prognostic factors in gastric cancer.
Histol Histopathol. 15: 455-62, 2000.
[Journal]
100)  Kleer CG, Bryant BR, Giordano TJ, Sobel M, Merino MJ.
Genetic Changes in Chromosomes 1p and 17p in Thyroid Cancer Progression.
Endocr Pathol. 11: 137-143, 2000.
[Journal]
101)  Otis CN, Krebs PA, Quezado MM, Albuquerque A, Bryant B, San Juan X, Kleiner D, Sobel ME, Merino MJ.
Loss of heterozygosity in P53, BRCA1, and estrogen receptor genes and correlation to expression of p53 protein in ovarian epithelial tumors of different cell types and biological behavior.
Hum Pathol. 31: 233-8, 2000.
[Journal]
102)  Conley B, O'Shaughnessy J, Prindiville S, Lawrence J, Chow C, Jones E, Merino MJ, Kaiser-Kupfer MI, Caruso RC, Podgor M, Goldspiel B, Venzon D, Danforth D, Wu S, Noone M, Goldstein J, Cowan KH, Zujewski J.
Pilot trial of the safety, tolerability, and retinoid levels of N-(4-hydroxyphenyl) retinamide in combination with tamoxifen in patients at high risk for developing invasive breast cancer.
J Clin Oncol. 18: 275-83, 2000.
[Journal]
103)  Middleton LP, Palacios DM, Bryant BR, Krebs P, Otis CN, Merino MJ.
Pleomorphic lobular carcinoma: morphology, immunohistochemistry, and molecular analysis.
Am J Surg Pathol. 24: 1650-6, 2000.
[Journal]
104)  Kleer CG, Giordano TJ, Merino MJ.
Squamous cell carcinoma of the thyroid: an aggressive tumor associated with tall cell variant of papillary thyroid carcinoma.
Mod Pathol. 13: 742-6, 2000.
[Journal]
105)  Cardiff RD, Anver MR, Gusterson BA, Hennighausen L, Jensen RA, Merino MJ, Rehm S, Russo J, Tavassoli FA, Wakefield LM, Ward JM, Green JE.
The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting.
Oncogene. 19: 968-88, 2000.
[Journal]

This page was last updated on 9/29/2008.