1 Ryan FJ., Lederberg J. Reverse-mutation and adaptation in leucineless Neurospora Proc. Nat. Acad. Sci. U.S. 32: 163-173. (1946) 3 Lederberg J., Tatum E.L. Detection of biochemical mutants of microorganisms. J. Biol. Chem. 165: 381-382. (1946) 4 Lederberg J., Tatum E.L. Novel genotypes in mixed cultures of biochemical mutants of bacteria Cold Spring Harbor Symp. Quant. Biol. 11: 113-114. (1946) 5 Lederberg J. A nutritional concept of cancer. Science 104: 428. (1946) 6 Tatum E.L., Lederberg J. Gene recombination in the bacterium Escherichia coli. J. Bacteriol. 53: 673-684. (1947) 7 Lederberg J., Tatum E.L. Gene recombination in Escherichia coli. Nature 158: 558. (1946) 8 Lederberg J. The nutrition of Salmonella. Arch. Biochem. 13: 287-290. (1947) 9 Lederberg J. Gene recombination and linked segregations in Escherichia coli Genetics 32: 505-525 (1947) . 9b Historical retrospective: Genetics 117: 1-4 (1987). 9 a. Lederberg, J. Genetic Recombination in Escherichia coli. Ph.D. dissertation, Yale University, 1947 v. + 47pp., 9 tables, 1 fig., unpublished typescript, 4to. 10 Giles N.H. Jr., Lederberg E.M. Induced reversions of biochemical mutants in Neurospora crassa Am. J. Bot. 35: 150-157. (1948) 11 Lederberg J. Problems in microbial genetics. Heredity 2: 145-198 (1948) 12 Lederberg J. Gene control of beta-galactosidase in Escherichia coli. Abstract, Genetics 33: 617-618. (1948) \" (== Q/12) Rec. GSA 17:46 13 Lederberg E.M. The mutability of several lac- mutants of Escherichia coli Genetics 33: 617. (1948) \" (== Q/13) 14 Lederberg J. Detection of fermentative variants with tetrazolium. J. Bacteriol. 56: 695. (1948) 15 Lederberg J., Zinder N.D. Concentration of biochemical mutants of bacteria with penicillin. J. Am. Chem. Soc. 70: 4267-4268. (1948) . 15a Lederberg, J. .. Current Contents LS/30 (33) 17 Aug. 1987 p. 16. Davis, B.D. p. 17 16 Lederberg J. Aberrant heterozygotes in Escherichia coli. Proc. Nat. Acad. Sci. U.S. 35: 178-184. (1949) 17 Lederberg J. Bacterial variation. Ann. Rev. Microbiol. 3: 1-22. (1949) 18 Doudoroff M., Hassid W.Z., Putman E.W., Potter,A.L., Lederberg J. Direct utilization of maltose by Escherichia coli. J. Biol. Chem. 179: 921-934. (1949) 19 Lederberg J. Isolation and characterization of biochemical mutants of bacteria Meth. in Med. Res. 3: 5-22 (1950) 20 Lederberg J. The selection of genetic recombinations with bacterial growth inhibitors. J. Bacteriol. 59: 211-215. (1950) 21 Lederberg J. The Beta-D-galactosidase of Escherichia coli, Strain K-12 J. Bacteriol. 60: 381-392. (1950) 22 Zelle M.R., Lederberg J. Single-cell isolations of diploid heterozygous Escherichia coli. J. Bacteriol. 61: 351-355. (1951) 23 Lederberg J. Streptomycin-resistance: A genetically recessive mutation J. Bacteriol. 61: 549-550. (1951) 24 Lederberg J. Prevalence of Escherichia coli strains exhibiting genetic recombination. Science 114: 68-69. (1951) 25 Lederberg J., Lederberg E.M., Zinder N.D., Lively, E.R. Recombination analysis of bacterial heredity. Cold Spring Harbor Symp. Quant. Biol. 16: 413-443. (1951) 26 Lederberg J. Genetic Studies with Bacteria. in (L.C. Dunn, ed.) Genetics in the 20th Century MacMillan, New York 263-289. (1951) (Symposium at Genetics Jubilee, Cleveland, Sept. 1950) 26.a Lederberg J. (ed.) Papers in microbial genetics: bacteria and bacterial viruses Univ. Wisconsin Press, 303 pp. (1951) 26.b Lederberg J. Inheritance, variation and adaptation. in (C.N. Werkman and P.W. Wilson eds.) in Bacterial Physiology Academic Press, N.Y., Chap. 3: 67-100 (1951) 27 Lederberg J., Lederberg E.M. Replica plating and indirect selection of bacterial mutants J. Bacteriol. 63: 399-406. (1952) .ig 28 lysogenicity abstract; see Q/16 .. 29 Zinder N.D., Lederberg J. Genetic exchange in Salmonella. J. Bacteriology 64: 679-699. (1952) 30 Lederberg E.M. Allelic relationships and reverse mutation in Escherichia coli Genetics 37: 469-483. (1952) \"* kw mutability Lac 31 Lederberg J., Cavalli-Sforza L.L., Lederberg E.M. Sex compatibility in Escherichia coli. Genetics 37: 720-730. (1952) 32 Lederberg E.M., Lederberg J. Genetic studies of lysogenicity in Escherichia coli. Genetics 38: 51-64. (1953) 33 Lederberg J. Cell genetics and hereditary symbiosis. Physiol. Rev. 32: 403-430. (1952) 34 Cavalli-Sforza L.L., Lederberg J., Lederberg E.M. An infective factor controlling sex compatibility in Bacterium coli J. Gen. Microbiol. 8: 89-103. (1952) 35 Lederberg J., Tatum E.L. Sex in bacteria: genetic studies, 1945-1952. Science 118: 169-175. (1953) 36 Bernstein A., Lederberg J. Agglutination of motile Salmonellas by acridines. J. Bacteriol. 69: 142-146. (1955) 37 Stocker B.A.D., Zinder N.D., Lederberg J. Transduction of flagellar characters in Salmonella. J. Gen. Microbiol. 9: 410-433. (1953) 38 Lederberg J., Edwards P.R. Serotypic recombination in Salmonella. J. Immunol. 71: 232-240. (1953) 39 Lederberg J. "Genetics and microbiology" in Symposium on Perspectives and Horizons in Microbiology. June 1955, Rutgers Univ. Press, Chap. 3, pp. 24-39. (1955) 40 Cavalli-Sforza L.L., Lederberg J. Genetics of resistance to bacterial inhibitors in Symp. on growth inhibition & chemotherapy International Congress of Microbiology (1953) Rome. 108-142 .ig 41 Was Genetics and Chemotherapy, with Luca. abandoned. See P64 .. 42 Lederberg J. Some biological aspects of bacterial genetics. Proc. 2nd Nat. Cancer Conf., Cincinnati, Vol. 2, 114-751 (1952) 43 Lederberg J. A simple method for isolating individual microbes. J. Bacteriol. 68: 258-259. (1954) 44 Nelson T.C., Lederberg J. Postzygotic elimination of genetic factors in Escherichia coli Proc. Nat. Acad. Sci. U.S. 40: 415-419. (1954) 45 Lederberg J. Recombination mechanisms in bacteria. J. Cell. Comp. Physiol., suppl. 2, 45: 75-108. (1955) 46 Lederberg J. Bacterial protoplasts induced by penicillin. Proc. Nat. Acad. Sci. U.S. 42: 574-577. (1956) 47 Lederberg J. Prospects for the genetics of somatic and tumor cells. Ann. N.Y. Acad. Sci. 63: 662-665. (1956) 48 Lederberg J., Lederberg E.M. "Infection and Heredity" in Cellular Mechanisms in Differentiation and Growth Sym. Soc. Growth and Development (D. Rudnick Ed.) Princeton Univ. Press 101-124. (1956) 49 Lederberg J. Linear inheritance in transductional clones. Genetics 41: 845-871. (1956) 50 Lederberg J. Mechanism of action of penicillin. J. Bacteriol. 73: 144. (1957) 51 Lederberg J. "Comments on gene-enzyme relationship" in Enzymes: Units of Biological Structure and Function. Ford Hospital Intl. Symp. (O.H. Gaebler, Ed.) Academic Press, N.Y. (1956) 52 Nelson T.C. Sexual competence in Escherichia coli. J. Cell and Comp. Physiol. 48: 271-292. (1956) 53 Cavalli-Sforza L.L., Lederberg J. Isolation of preadaptive mutants in bacteria by sib selection. Genetics 41: 367-381. (1956) * kw indirect selection. 53a Cavalli-Sforza L.L. Indirect selection and the origin of resistance. Ciba Fn. Symposium on Drug Resistance in Micro-Organisms. pp 30-40, (1957); J & A Churchill Ltd., London * kw JL discussion: INH acetylation polymorphism * kw arguments with Hinshelwood 54 Morse M.L., Lederberg E.M., Lederberg J. Transduction in Escherichia coli K-12. Genetics 41: 142-156. (1956) 55 Lederberg J. Genetic recombination in bacteria. Science 122: 920. (1955) 56 Lederberg J. Genetic transduction. American Scientist 44: 264-280. (1956) 56b Lederberg J. Restoring bacterial toxigenicity. Science 173:104-105. (1971) 57 Lederberg J. Conjugal pairing in Escherichia coli. J. Bacteriol. 71: 497-498. (1956) 58 Morse M.L., Lederberg E.M., Lederberg J. Transductional heterogenotes in Escherichia coli. Genetics 41: 758-779. (1956) 59 Bradley S.G., Lederberg J. Heterokaryosis in Streptomyces. J. Bacteriol. 72: 219-225. (1956) 60 Lederberg J., Iino T. Phase variation in Salmonella. Genetics 41: 743-757. (1956) 61 Rotman B. A simplified device for continuous growth of microorganisms J. Bacteriol. 70: 485-486. (1955) 62 Skaar P.D. A binary mutability system in Escherichia coli. Proc. Nat. Acad. Sci. U.S. 42: 245-249. (1956) 63 Lederberg J. Concluding discussion in McElroy W.D., Glass B. Eds Symposium on The Chemical Basis of Heredity. John Hopkins Press, Baltimore, pp 752-754. (1956) .ig 64 ms. for Book on Bacterial Recombination, (1957) abandoned. Cf P41 .. 65 Iino T., Lederberg J. Transductional analysis of phase variation in Salmonella. Kagaku 26: 575 (1956) Tokyo (in Japanese) 66 Morse M.L. Transduction and Transformation. Symp. on Subcellular Particles & neoplastic Process. (1957) Ann. N.Y. Acad.Sci. 68:324-334.. 67 Skaar P.D., Richter A., Lederberg J. Correlated selection for motility and Sex-incompatibility in Escherichia coli K-12. Proc. Nat. Acad. Sci. U.S. 43: 329-333. (1957) 68 Rotman B. On the mechanism of sonic lysis of bacteria. J. Bacteriol. 72: 827-830. (1957) 69 Lederberg J. Viruses, genes and cells. Bact. Rev. 21: 133-139. (1957) . Also, Texas Rep. Biol. Med., 15(3):811-826 (1957) and Gazzetta Sanitaria, #6, 1959 70 Lederberg J., St Clair J. Protoplasts and L-type growth of Escherichia coli. J. Bacteriol. 75: 143-160. (1958) 71 Wright R.E., Lederberg J. Extranuclear transmission in yeast heterokaryons. Proc. Natl. Acad. Sci. U.S. 43: 919-923. (1957) 72 Lederberg J. Sibling recombinants in zygote pedigrees of Escherichia coli Proc. Natl. Acad. Sci. 43: 1060-1065. (1957) 73 Rotman B. Regulation of enzymatic activity in the intact cell: The Beta-D-galactosidase of Escherichia coli. J. Bacteriol. 76: 1-14. (1958) 74 Lederberg J., Holloway B.W., Lederberg E.M., et al. Symposium on Bacterial and Viral Genetics Aust. J. Sci. 20: 71-76. Canberra (1957) 75 Lederberg J. Bacterial Reproduction Harvey Lectures 53: 69-82. (1958) 76 Nossal G.J.V., Lederberg J. Antibody production by single cells. Nature 181: 1419-1420. (1958) 77 Lederberg J., Cowie D.B. Moondust [The study of this covering layer by space vehicles may offer clues to the biochemical origin of life] Science 127: 1473-1475. (1958) 78 Lederberg J. Genetic approaches to somatic cell variation: summary comment J. Cell. Comp. Physiol. 52 suppl. 1:383-402. (1958) \"KW:epinucleic ; somatic cell genetics; do embryology on embryos 80 Lederberg J. Genes and antibodies. Science 129: 1649-1653. (1959) \"Also published: \"Stanford Med. Bull. 19:53-61 (1961) with postscript 3/61 \" J. NIH Res. 6:72-80 1994 with commentary by Norman Klinman \" and interview by Keith Haglund and Christine Grammes. \" See also P-279; T-62 81 Lederberg J. A view of genetics. Les Prix Nobel en 1958: 170-189. (1959) \"Also published: Science 131:269-276 (1960) \"Stanford Medical Bull. 17:120-132 (1959) \"Angewandte Chemie 71: 473-480 (1959) \" Ergebnisse und Probleme der Genetik \"Lecture was given 29 May 1959. 82a Lederberg J. Biochemistry of Human Genetics. Ciba Foundation Symposium. (1959). extensive comments transcribed. (Naples May, 1959). 82b. Lederberg, J. Cellular Aspects of Immunity. Ciba Foundation Symposium. (1960). extensive comments transcribed. (Royaumont, 1959). 83 Lederberg J. Genetics of bacteria and viruses. Six filmed lecs. in ser. "Genetics", Herskowitz I.H. ED. McGrawHill, N.Y. (1960) 84 Lederberg J. Bacterial genes. Triangle 5: 107-113. (1961) 85 Lederberg E.M. Genetic and Functional aspects of galactose metabolism in Escherichia coli K-12. in Microbial Genetics, 10th Sym. Soc. Gen. Microbiol., Great Britain, 115-131. (1960) 86 Hirota Y. The effect of acridine dyes on mating type factors in Escherichia coli. Proc. Natl. Acad. Sci. U.S. 46: 57-64. (1960) 87 Lederberg J. Exobiology: approaches to life beyond the earth. Science 132: 393-400. (1960) .ig also Space Research. Proc. 1st Intl. Space Science Symposium Exobiology: experimental approaches to life beyond the earth. H.K. Bijl, ed. Amsterdam: North Holland 1960 pp 1153- 1170. COSPAR The Search for Life beyond the Earth. New Scientist 7:386-88. in Science in Space. The biological sciences and space research. Space Science Board, NAS 1960 JL & K Hartline also in Goldsmith,D. Quest for extraterrestrial life. Univ. Science Books. 1980 also in ExtraTerrestrial Life, NAS 1966 .. 89 Sneath P.H.A., Lederberg J. Inhibition by periodate of mating in Escherichia coli K-12 Proc. Natl. Acad. Sci. U.S. 47: 86-90. (1961) 90 Nester E.W., Lederberg J. Linkage of genetic units of Bacillus subtilis in DNA transformation. Proc. Natl. Acad. Sci. U.S. 47: 52-55. (1961) 91 Lederberg J. Approaches to life beyond the earth. Film, Origin of Life, Produced by Office of Life Science National Aeronautics and Space Admin. (1961) 92 Novick A., Lederberg J. Challenges to Biology. Bull. Atomic Scientists 17:203-206. (1961) 94.a Iino T. Stabilizer of antigenic phases in Salmonella abortusEqui. Genetics 46: 1465-1469. (1961) 94.b Iino T. Anomalous homology of flagellar phases in Salmonella. Genetics 46: 1471-1474. (1961) 94.c Lederberg J. A duplication of the H1 (Flagellar antigen) In Salmonella Genetics 46: 1475-1481. (1961) 95 Moffat S., Shneour E.A., Lederberg J. (epilogue) Life Beyond the Earth. = Vistas of Science 11, Nat. Sci. Teachers Assn. Scholastic Book Services, N.Y. (1961) 96 Orskov F., Orskov I. The Fertility of Escherichia coli antigen test strains in crosses with K-12. Acta Path. et Microbiologica Scand. 51: 280-290. (1961) 97 Makela P.H., Lederberg J., Lederberg E.M. Patterns of sexual recombination in enteric bacteria. Genetics 47: 1427-1439. (1962) 98 Cook A., Lederberg J. Recombination studies of lactose nonfermenting mutants in Escherichia coli K-12. Genetics 47: 1335-1353. (1962) 99 Iino T., Lederberg J. "Genetics of Salmonella" in The World Problem of Salmonellosis. Dr. W. Junk (Pub.), Van Oye R. (Ed.) The Hague, Holland. pp. 111-142. (1964) 100 Sagan C., Lederberg J. Microenvironments for life on Mars. Proc. Nat. Acad. Sci. U.S. 48: 1473-1475. (1962) 101 Richardson C.C., Schildkraut C.L., Aposhian H.V., Kornberg,A.H., Bodmer,W., and Lederberg, J. Studies on the replication of DNA by Escherichia coli polymerase. in Sym. Informational Macromolecules (Inst. Microbiology Rutger U.) Academic Press. p 13-26. (1963) 102 Lederberg J. "Biological Future of Man" in: Wolstenholme G. (Ed.) Man and His Future Ciba Found. Sym. 1962, 263-273. J. A. Churchill Ltd. London; Little Brown Co. Boston (1963) 103 Makela P.H. Hfr-males in Salmonella abony. Genetics 48: 423-429. (1963) 104 Nester E.W., Ganesan A.T., Lederberg J. Effects of mechanical shear on genetic activity of Bacillus subtilis DNA. Proc. Nat. Acad. Sci. U.S. 49: 61-68. (1963) 105 Nester E.W., Schafer M., Lederberg J. Gene linkage in DNA transfer: a cluster of genes concerned with aromatic biosynthesis in Bacillus subtilis. Genetics 48: 529-553. (1963) 106 Lederberg J. Molecular biology, eugenics and euphenics. Nature 198: 428-429. (1963) 107 Ganesan A.T., Lederberg J. Physical and biological studies on transforming DNA. J. Mol. Biol. 9: 683-695. (1964) 108 Levinthal E.C., Hundley L., Lederberg J. Multivator: a biochemical laboratory for Martian experiments. in Life Sciences and Space Research II. 4th Intl. Space Science Sympos., 1963 Florkin M. & Dollfus A. (Eds.) North Holland Publishing Co., Amsterdam. (1964) 110 Lederberg J. A crisis in evolution. New Scientist 21: 212-213. (1963) repr. in Calder 1983 Update: New dreams for old. NS 144 (1947): 51-52. 1994. 10/15/94 111 Lederberg J. Life beyond the earth. Stanford Today, Winter (1963) 112 Lederberg E.M., Cavalli-Sforza L.L., Lederberg J. Interaction of streptomycin and a suppressor for galactose- fermentation in E. coli K-12. Proc. Nat. Acad. Sci. U.S. 51: 678-682. (1964) 113 Lederberg J. Computation of Molecular Formulas for Mass Spectrometry. Holden-Day, Inc., San Francisco (1964) 114 Lederberg J. Tables and an algorithm for calculating functional groups of organic molecules in high resolution mass spectrometry. NASA Sci. & Tech. Aerospace Rpt. STAR No. N64-21426. (1964) 115 Lederberg J. Calculation of molecular formulas in high-resolution mass spectrometry. in: Structure Elucidation of Natural Products by Mass Spectrometry, v. 2 (Budzikiewicz,H. Djerassi,C., Williams,D.H. eds) Holden-Day Inc. S.F., (1964) 116 Pfeiffer J.E. A visit with Joshua Lederberg. THINK, May-June. (1964) 117 Lederberg J., Wightman M. Calculation of upper limit of hydrogens of an organic formula for analysis for mass spectra. Anal. Chem. 36:2365. (1964) 118 Lederberg J. Classification of Polycyclic Systems as "Polycenes". withdrawn (1964) 119 Lederberg J., Wightman M. A subalgol program for calculation of molecular compositional formulas from mass spectral data. NASA Sci. & Tech. aerospace Rpt. STAR No. N66-11689 (1964) 120 Lederberg J. Topological mapping of organic molecules. Proc. Nat. Acad. Sci. U.S. 53: 134-139. (1965) 121 Lederberg J. Signs of Life: criterion system of exobiology Nature 207: 9-13. (1965) 122 Ganesan A.T., Lederberg J. A cell membrane bound fraction of bacterial DNA. Biochem. Biophys. Res. Com. 18: 824-835. (1965) 123 Aplin R.T., Budzikiewicz H., Horn H.S., Lederberg J. Application of a logarithmic transfer response circuit to the recording of mass spectra and especially peaks from metastable ions. Anal. Chem. 37: 776-777. (1965) 124 Lederberg J. DENDRAL-64. A system for computer construction, enumeration & notation of organic molecules as tree structures and cyclic graphs. Part I. Notational algorithm for tree structures. NASA CR-57029. STAR No. N65-13158. (1964) 125 Lederberg J. Coded inputs and computed displays of chemical structure withdrawn (1965) 126 Lederberg J. DENDRAL-64. Part II. Topology of cyclic graphs. NASA CR-68898. STAR No. N66-14074. (1965) 127 Lederberg J. Systematics of organic molecules, graph topology and Hamilton circuits. A general outline of the DENDRAL system. NASA CR-68899. STAR No. N66-14075. (1965) 128 Lederberg J. Hamilton circuits of convex trivalent polyhedra (up to 18 vertices). Am. Math Monthly 74:522-527 (1965) 129 Lederberg J. Planetary exploration and biological research withdrawn (1965) 130 Halpern B., Westley J.W., von Wredenhagen I., Lederberg J. Optical resolution of D,L amino acids by gas chromatography and mass spectrometry. Biochem. Biophys. Res. Com. 20: 710-714. (1965) 131 Lederberg J. Computers and the life sciences. Book review, Science 150: 1576-1577. (1965) 132 Lederberg J. Interview, Science Talks, BBC, London. (1965) \" 133 Lederberg J. \" Canonical description and algorithmic test of isomorphism of cyclic graphs. \" Comm. ACM. withdrawn. (1966) 134 Lederberg J. Online computation of molecular formulas from mass number. NASA CR-95977; Accession # x68-18613. (1966) 135 Lederberg J. Experimental genetics and human evolution. Amer. Naturalist 100: 519-531. (1966) \" also Bull Atom. Sci. 22(8):4-11. (1966) \" also pp. 670-688 in Schwarz, R. (ed.) \" Menschliche Existenz und Moderne Welt \" Berlin: Gruyter (1967) \" kw algeny 136 Lederberg J. The utility of anticipation. The Pharos, July (1966) 29(3): pp. 89,93. 137 Lederberg J. Introductory remarks in Current Topics in Developmental Biology. in: Vol. I, Monroy A. & Moscona A.A. (Eds.) Academic Press, New York. (1966) 138 Lanyi J.K., Lederberg J. A fluorescent Method for the detection of excreted ribonuclease around bacterial colonies. J. Bact. 92:1469-1472. (1966) 139 Lederberg J. The microbe as a model of evolution. IMPACT Unesco, withdrawn (1966) 140 Lederberg J. "L'Exobiologie". Encyclopedie de l'espace. Editions Rombaldi, Paris. (1966) 141 Bodmer W., Lederberg J. Census data for studies of genetic demography. Proc. III Int. Congress of Human Genetics John Hopkins Press, Baltimore. p 459-471. (1967), Crow J.F., Neel J.V. (Eds.) 142 Lederberg J. Planetary Exploration and Biological Research. Impact of Space Exploration on Society. Am. Astronautical Society. p. 155-158. (1966) rem: Vol. 8, Sci. Tech. Series. 144 Lederberg J. Biology and the Rational Animal. The Sciences , New York Academy of Sciences 7: 28-32. (1967) 145 Lederberg J. Eutechnics: a motif for technology. Technology Week, 20: 4: 49-55. (1967) 145B -- reprinted in polemic, Literaturn. Gazeta, Moscow: #20 May 15, 1969. 146 Halpern B., Westley J.W., Anderson P., Lederberg J. Demonstration of the stereospecific action of microorganisms in soil by gas liquid chromotography. Anal. Biochem. 17:179-182. (1966) 147 Lederberg J. Some problems of instant medicine. Biomedical research: its side effects and challenges. Stanford M.D., October, 13-17 (1967) and Saturday Review May 6 (1967) 148 Sagan C., Levinthal E.C., Lederberg J. Contamination of Mars. Science 159: 1191-1196. (1967) 149 Halpern B., Westley J.W., Levinthal E.C., Lederberg J. The Pasteur Probe: an assay for molecular asymmetry in Life Sciences and Space Research (COSPAR). COSPAR p. 239-249. (1967) rem: Florkin M.,Dollfus A. (Eds.) 150 Lederberg J., Feigenbaum E.A. Mechanization of inductive inference in organic chemistry in: Formal Representation of Human Judgement. Kleinmuntz B. (Ed.) John Wiley & Sons, NY p. 187-218. (1968) 151. Lederberg, J., 1969. "Topology of Molecules" in The Mathematical Sciences (COSRIMS) with George A.W. Boehm), MIT Press, p. 37-51. 152. Lederberg, J., 1967. A geneticist looks at contraception and abortion. Colloq. on The Changing Mores of Biomedical Research. Annals of Internal Medicine, (Am. Coll Physicians) Vol. 67, No. 3, Pt. II, Suppl. 7:25-27. 153. Lederberg, J., 1968. "Haldane's Biology and Social Insight" in Haldane and Modern Biology. (K.R. Dronamraju, ed.), The Johns Hopkins Press, Baltimore, p. 219-231. 154. Lederberg, J., 1969. "Francis J. Ryan" in University on the Heights. (Wesley First, ed.), Doubleday and Co., Inc. Garden City, New York, p.105-109. 155. Lederberg, J., 1970. DENDRAL III. Interim Report to NASA. Grant NsG 81-60, 9/28/70 (revised from 3/13/68 report). 156. Lederberg, J., 1968. Science and Man. SAM columns from Washington Post Doubleday & Co. (book intended, but project dropped) 157. Lederberg, J., 1971. "The Gene" in 1971 Encyclopedia Americana. Revised 1988 158. Lederberg, J., 1969. "Genetics" in Encyclopaedia Britannica 1969 Yearbook of Science and the Future, p. 318-321. 159. Lederberg, J., 1970. "Tomorrow's Babies" in Proceedings of the 6th World Congress on Fertility and Sterility. Tel Aviv, May 20-27, 1968. The Israel Academy of Sciences and Humanities, Jerusalem. 160. Levinthal, E.C., J. Lederberg, and C. Sagan, 1968. "Relationship of Planetary Quarantine to Biological Search Strategy" in Life Sciences and Space Research. North Holland, Amsterdam, p. 136-145. 161. Lederberg, J., 1969. "Health in the World of Tomorrow". PAHO/WHO Lectures on the Biomedical Sciences, 1968. Pan American Health Organization, Scientific Publication No. 175. 162. Lederberg, J., et al. 1968. "Summation and Perspective" in Image Processing in Biological Science. (Diane M. Ramsey, ed.), UCLA Forum in Medical Sciences, No. 9, p. 219-242. 163. Lederberg, J., 1969. Book Review. JBS: The Life and Work of J.B.S. Haldane, by R.W. Clark in Book World (Washington Post), 1/5/69. 164. Lederberg, J., G.L. Sutherland, B.G. Buchanan, E.A. Feigenbaum, A.V. Robertson, A.M. Duffield, and C. Djerassi, 1969. Applications of artificial intelligence for chemical inference. I. The number of possible organic compounds. Acyclic structures containing C, H, O, and N. J. Am. Chem. Soc. 91:2973-76. 165. Lederberg, J., G.L. Sutherland, B.G. Buchanan, E.A. Feigenbaum, A.V. Robertson, A.M. Duffield, and C. Djerassi, 1969. Applications of artificial intelligence for chemical inference. II. Interpretation of low resolution mass spectra of ketones. J. Am. Chem. Soc. 91:2977-2981. 166. Lederberg, J., 1970. "Humanics and Genetic Engineering" in Encyclopaedia Britannica 1970 Yearbook of Science and the Future. 166a. Lederberg, J., 1969. Genetic engineering: controlling man's building blocks. Today's Health 47:25, November 1969. 167. Lederberg, J., 1969. Mars through a crystal ball. Applied Optics 8:1269-1270. .ig 168. [Lederberg, J., 1969. See Terry lectures 1989 P272 Silliman Lectures. Yale University, April-May 1969. 1. DNA and the nature of man. Answer to GG Simpson 4/28/69 2. The direction of human evolution: goals, techniques, policies 4/30/69 3. Prometheus Perplexed: Untrammeled science and the freedom of the person 5/2/69 project never completed] .. 169. Lederberg, J., 1969. Racial alienation and intelligence. Harvard Ed. Rev. 39:611-615, Summer 1969. 170. DENDRAL BOOK. W.H. Freeman & Co. (to be published) Project superseded by p255 171. Schroll, G. A.M. Duffield, C. Djerassi, B.G. Buchanan, G.L. Sutherland, E.A. Feigenbaum, and J. Lederberg, 1969. Applications of artificial intelligence for chemical inference. III. Aliphatic ethers diagnosed by their low-resolution mass spectra and nuclear magnetic resonance data. J. Am. Chem. Soc. 91:7440-7445. 172. Lederberg, J., 1969. Book Review. The Black Death by Philip Ziegler, in Book World (Washington Post), June 15, 1969. 173. Ciferri, O., S. Barlati and J. Lederberg, 1970. Uptake of synthetic polynucleotides by competent cells in Bacillus subtilis. J. Bact. 104:684-688. 173a. Barlati, S. and O. Ciferri, 1970. Incorporation of 5-methyl- and 5-hydroxy-tryptophan into the protein of Bacillus subtilis. J. Bact. 101:166-172. Barlati, S., 1970. Incorporation of uridine into Bacillus subtilis and SPP1 bacteriophage deoxyribonucleic acid. J. Bact. 101:330-332. Majerfeld, I., S. Barlati and O. Ciferri, 1970. Tryptophanless death in Bacillus subtilis. J. Bact. 101:350-354. Barlati, S. and I. Majerfeld, 1970 Partial characterization of the factor responsible for tryptophanless death in Bacillus subtilis. J. Bact. 101:355-360. Barlati, S., 1970. Polyribosomes from Bacillus subtilis during amino acid starvation in the presence and in the absence of actinomycin. J. Bact. 101:925-930. 174. Masursky, H. et al. (incl. J. Lederberg), 1970. Television Experiment for Mariner Mars 1971. Exobiology: Search for evidence of life or biologic habitats. Icarus 12:10-45. 175. Lederberg, J., G.L. Sutherland, B.G. Buchanan, and E.A. Feigenbaum, 1969. A heuristic program for solving a scientific inference problem: summary of motivation and implementation. Stanford AI Memo AIM-104. 175a. Buchanan, B., G. Sutherland, and E.A. Feigenbaum, 1969. Heuristic DENDRAL: a program for generating explanatory hypotheses in organic chemistry in Machine Intelligence IV (B. Meltzer and D. Michie, eds.), Edinburgh University Press, p. 209-254. 175b. Buchanan, B., G. Sutherland, and E.A. Feigenbaum, 1970. Rediscovering some problems of artificial intelligence in the context of chemistry in Machine Intelligence V (B. Meltzer and D. Michie, eds.), Edinburgh University Press, p. 253-280. 175c. Feigenbaum, E.A., Lederberg, J. and Buchanan,B., 1968 Heuristic DENDRAL: a program for generating explanatory hypotheses in organic chemistry . Proc. Hawaii Intl. Conference on System Sciences IEEE Group on Information Theory University of Hawaii Press 176. Lederberg, J., 1969. Biological warfare and the extinction of man. Stanford M.D. 8:15-18, Fall 1969. 176a. Lederberg, J., 1971. "Technology and Peace: the role of biological research" in Peaceful Change in Modern Society (E. Berkeley Tompkins, ed.), Hoover Institution Press, p. 71-85. 177. Lederberg, J., 1970. "Orthobiosis: The Perfection of Man" in Nobel Symposium XIV The Place of Value in a World of Facts, held in Stockholm, Sweden, 9/69 (Arne Tiselius and Sam Nilsson, eds.), John Wiley & Sons, In., New York, p.29-58. 178. Lederberg, J., 1970. "From Prometheus to Frankenstein" in Scientific Proceedings in Summary Form, 123rd Annual Meeting of the American Psychiatric Association, San Francisco, California, May/11-15, 1970. 178b. Lederberg, J., 1970. "In Search of the Environment", reported in Bull. Am. Acad. Arts & Sci. 24:14-22, 10/70. 179. Lederberg, J., 1970. "Human Implications of Biological Discovery" in Toward Century 21 (C.S. Wallia, ed.) Basic Books, New York, p.39-52. 180. Buchs, A., A.M. Duffield, G. Scholl, C. Djerassi, A.B. Delfino, B.G. Buchanan, G.L. Sutherland, E.A. Feigebaum, and J. Lederberg, 1970. Applications of artificial intelligence for chemical inference. IV. Saturated amines diagnosed by their low resolution spectra and nuclear magnetic resonance spectra. J. Chem. Soc. 92:6831-6838. 181. Sheikh, Y.M., A. Buchs, A.B. Delfino, G. Scholl, A.M. Duffield, C. Djerassi, B.G. Buchanan, G.L. Sutherland, E.A. Feigenbaum, and J. Lederberg, 1970. Applications of artificial intelligence for chemical inference. V. An approach to the computer generation of cyclic structures. Differentiation between all the possible isomeric ketones of composition C6H10O. Org. Mass Spec. 4:493-501. 182. Buchs, A., A.B. Delfino, A.M. Duffield, C. Djerassi, B.G. Buchanan, E.A. Feigenbaum, and J. Lederberg, 1970. Applications of artificial intelligence for chemical inference. VI. Approach to a general method of interpreting low resolution mass spectra with a computer. Helvitia Chimica Acta 53:1394-1417. 183. Lederberg, J., 1971. "Food Additives" in The Social Responsibility of the Scientist. (Martin Brown, ed.), The Free Press - A Division of the Macmillan Co., New York, p.119-130. 184. Epstein, Samuel and Marvin Legator (eds.), foreword by Joshua Lederberg, 1971. in Mutagenicity of Pesticides - Concepts and Evaluation. MIT Press, Cambridge, Mass. 185. (see 174). 186. Feigenbaum, E.A., B.G. Buchanan, J. Lederberg, 1971. On generality and problem solving: a case using the DENDRAL program in Machine Intelligence 6, (B. Meltzer and D. Michie, eds.), Edinburgh University Press, p.165-190. 187. Hunn, G. and J. Lederberg, 1971. Genetic Counselor, in Machine Intelligence 6, (B. Meltzer and D. Michie, eds.), Edinburgh University Press, p.191-203. 188. Lederberg, J., 1971. Genetic engineering, or the amelioration of genetic defect. Pharos 34:9-12, January 1971. 188a. Lederberg, J., 1970. Genetic engineering and the amelioration of genetic defect. Bio-Science 20:1307-1310, December 1970. 189. Lederberg, J., 1971. Human values in a technological society. Technology as diabolism. Dimensions 5:9-15, Winter 1971. 190. Lederberg, J., 1972. "Cell Fusion and the New Genetics" in 1972 Science Year of the World Book Encyclopedia, p.191-203. 191. Buchanan, B. and J. Lederberg, 1971. "The Heuristic DENDRAL Program for Explaining Empirical Data" in Proceedings of the IFIP Congress 71, Ljubljana, Yugoslavia, North Holland Publ. Co., Amsterdam, The Netherlands, p.91-100. 192. Reynolds, W.E., V.A. Bacon, J.C. Bridges, T.C. Coburn, J. Lederberg, E.C. Levinthal, E. Steed, R.B. Tucker, 1970. A computer operated mass spectrometer system. Analytical Chem. 42:1122-1129. 193. J. Lederberg, J., 1971. "Molecular Genetics" in Encyclopaedia Britannica 1971 Yearbook of Science and Future, p.304-307. 193b. J. Lederberg, 1972. "Molecular Genetics" in Encyclopaedia Britannica 1972 Yearbook of Science and Future. 193c. Lederberg, J., 1973. "Molecular Genetics" in Encyclopaedia Britannica 1973 Yearbook of Science and Future. 193d. Lederberg, J., 1974. "Molecular Genetics" in Encyclopaedia Britannica 1974 Yearbook of Science and Future. 194. Lederberg, J., 1972. "Use of Computer to Identify Unknown Compounds: The Automation of Scientific Inference" in Biochemical Applications of Mass Spectrometry, (G.R. Waller, ed.), John Wiley & Sons, New York, p.193-207. 195. Lederberg, J., 1971. "Biomedical Frontiers: Genetics" in The Challenge of Life - Biomedical Progress and Human Values, Roche Jubilee Symposium 8/31-9/3/71, F. Hoffmann-La Roche & Co., Ltd., Basle, Switzerland, p.15-25. [also disc. 39-42, 47-60, 140-142, 212-214 Also in Experientia 17:Suppl. 231-245 (1972) 195a. Lederberg, J., 1972. Options for genetic therapy. Medical Dimensions, p.16, March 1972. 196. Lederberg, J., 1972. The freedom and the control of science - notes from the ivory tower. Southern California Law Review 45:596-614. 197. Lederberg, J., 1972. The control of chemical and biological weapons. Stanford J. International Studies 7:22-44. 198. Lederberg, J., 1973. "Research: The Promethean Dilemma" in Hippocrates Revisited - A Search for Meaning, (R.J. Bulger, ed.), MEDCOM, New York, Chapter 16, pp. 159-165. 199. Epstein, Samuel (ed.), J. Lederberg, M. Legator, E. Carroll, J. Blaine (assoc. eds.), 1971. "Drugs of Abuse - Their Genetic and Other Chronic Nonpsychiatric Hazards", The MIT Press, Cambridge, Mass. 200. Buchs, A., A. Delfino, C. Djerassi, A. Duffield, B. Buchanan, E. Feigenbaum, J. Lederberg, G. Scholl, G. Sutherland, 1971. Application of artificial intelligence for chemical inference. VII. The application of artificial intelligence in the interpretation of low-resolution mass spectra. Advances in Mass Spectrometry 7:314-318. 201. Smith, D.H., B.G. Buchanan, R.S. Engelmore, A.M. Duffield, A. Yeo, E.A. Feigenbaum, J. Lederberg, C. Djerassi, 1972. Application of artificial intelligence for chemical inference. VIII. An approach to the computer interpretation of the high resolution mass spectra of complex molecules. Structure elucidation of estrogenic steroids. J. Am. Chem. Soc. 94:5962-5971. 202. Masursky, Harold et al. (incl. J. Lederberg), 1972. Mariner 9 television reconnaissance of Mars and its satellites: preliminary results. Science 175:294-305. 203. Lederberg, J., 1972. Pneumococcal transformation. Letter to the Editor of Nature, in reply to H.V. Wyatt (Nature 1/14/72). Nature 239:234, 9/22/72. 204. Buchanan, B.G., E.A. Feigenbaum, and J. Lederberg, 1971. A heuristic programming study of theory formation in science. Proceedings of the Second International Joint Conference on Artificial Intelligence, Imperial College, London (9/71). Also: Stanford AI Project Memo No. 145. 205. Lederberg, J., 1972. Rapid calculation of molecular formulas from mass values. J. Chem. Ed. 49:613. 206. Lederberg, J., 1972. "Biological Innovation and Genetic Intervention" in Challenging Biological Problems - Directions Toward Their Solution (American Institute of Biological Sciences 25th Anniversary Volume), John A. Behnke, ed., Oxford University Press, New York, p. 7-27. .ig (Adapted from a presentation to the Jubilee Symposium of Hoffmann-La Roche & Co., Ltd., held in Basel, Switzerland, 9/71 (latter portion of essay only). 206a. Lederberg, J., 1973. The perfection of man. Stanford M.D. 12:12-21, Spring 1973. .. 207. Klein, H.P., J. Lederberg, A. Rich, 1972. Biological experiments: the Viking Mars Lander. Icarus 16:139-146. 208. Patton, W., V. Bacon, A.M. Duffield, B. Halpern, Y. Hoyano, W. Pereira, J. Lederberg, 1972. Chlorination studies. I. The reaction of aqueous hypochlorous acid with cytosine. Biochem. Biophys. Res. Comm. 48:880-883. 208a. Pereira, W., Y. Hoyano, R. Summons, V. Bacon, A. Duffield, 1973. Chlorination studies. II. The reaction of aqueous hypochlorous acid with alpha-amino acids and dipeptides. Biochim. Biophys. Acta 313:170-180. 208b. Hoyano, Y., R. Summons, W. Pereira, A. Duffield. Chlorination studies. III. (dead issue - not published). 208c. Hoyano, Y., V. Bacon, R. Summons, W. Pereira, B. Halpern, A. Duffield, 1973. Chlorination studies. IV. The reaction of aqueous hypochlorous acid with pyrimidine and purine bases. Biochem. Biophys. Res. Comm. 53:1195-1199. .ig 209. Lederberg, J. Memoir on the Discovery of Genetic Recombination in Bacteria. (in preparation). -- SUPERSEDED by p/266,9 but see B209 directory Use folder for pre/postmature discovery .. 210. Smith, D., B. Buchanan, W. White, E. Feigenbaum, J. Lederberg, 1973. Applications of artificial intelligence for chemical inference. X. INTSUM. A data interpretation and summary program as applied to the collected mass spectra of estrogenic steroids. Tetrahedron 29:3117. 211. Sagan, C. et al. (incl. J. Lederberg), 1972. Variable features on Mars: preliminary Mariner 9 television results. Icarus 17:346-372. 212. Lederberg, J., 1974. "A System-analytic Viewpoint" in How Safe is Safe? - The Design of Policy on Drugs and Food Additives. Academy Forum. National Academy of Sciences, Washington, D.C., p. 66-94. 213. Masinter, L., N. Sridharan, J. Lederberg, D.H. Smith, 1974. Application of artificial intelligence for chemical inference. XII. Exhaustive generation of cyclic and acyclic isomers. J. Am. Chem. Soc. 96:7702-7714. 214. Lederberg, J., 1973. The genetics of human nature. Social Res. 40:375-406. 215. Lederberg, J., 1974. Prediction tables for doublets in high resolution mass spectrometry of organic molecules (not published). [MOLTAB notes] 216. Masinter, L.M., N.S. Sridharan, R.E. Carhart, D.H. Smith, 1974. Applications of artificial intelligence for chemical inference. XIII. The labeling of objects having symmetry. J. Am. Chem. Soc. 96:7714-7723. 217. Lederberg, J., 1972. Intervention: the promulgation of the good. Paley lecture at Cornell Medical Center, New York, 5/8/72 (not published). 218. Lederberg, J. article on Genetics & Psychiatry (promised for The American J. of Psychiatry). 219. Simek, J.W. and J. Lederberg, 1976. Systematic generation of acyclic structural isomers of organic compounds. J. Chem. Education (withdrawn). 220. Lederberg, J. and C. Sagan, 1974. The prospects for life on Mars: a post Mariner 9 assessment (not published). 221. Lederberg, J., 1972. "Genetic Predisposition to Hepatitis" in Hepatitis and Blood Transfusion, (G.N. Vyas, H.A. Perkins and R. Schmid, eds.), Grune and Stratton, New York, pp. 89-93. 222. Sagan, C., J. Veverka, P. Fox, R. Dubisch, R. French, P. Gierasch, L. Quam, J. Lederberg, E. Levinthal, R. Tucker, B. Eross, 1973. Variable features on Mars, 2, Mariner 9 global results. J. Geophys. Research 78:4163-4196. 223. Harris-Warrick, R.M., Y. Elkana, S.D. Ehrlich and J. Lederberg, 1975. Electrophoretic separation of B. subtilis genes (EcoRI/agarose gel electrophoresis). Proc. Nat. Acad. Sci. USA 72:2207-2211. 224. Dromey, R.G., B.B. Buchanan, D.H. Smith, J. Lederberg and C. Djerassi, 1975. Applications of artificial intelligence for chemical inference. XIV. A general method for predicting molecular ions in mass spectra. J. Org. Chem. 40:770-774. 225. Carhart, R.E., D. Smith, H. Brown and C. Djerassi, 1975. Applications of artificial intelligence for chemical inference. XVII. An approach to computer-assisted elucidation of molecular structure. J. Am. Chem. Soc. 97:5755-5762. 226. Bursztyn, H., V. Sgaramella, O. Ciferri and J. Lederberg, 1975. Transfectability of rough strains of Salmonella typhimurium. J. Bact. 124:1630-1634. 227. Sgaramella, V., S.D. Ehrlich, H. Bursztyn and J. Lederberg, 1976. Biological activity and molecular structure of DNA. I. Enhancement of transfecting activity of bacteriophage P22 DNA upon exonucleolytic erosion. J. Mol. Biol. 105:587-602. 228. Ehrlich, S.D., V. Sgaramella, and J. Lederberg, 1976. Biological activity and molecular structure of DNA. II. Bacteriophage T7 DNA transfects CaCl2-treated E. coli cells and is activated by erosion with lambda exonuclease. J. Mol. Biol. 105:603-609. 229. Lederberg, J., 1975. DNA Splicing: Will Fear Rob Us of Its Benefits? A.M.A. PRISM 3:33-37, November 1975. 229b. DNA research: uncertain peril and certain promise. pp. 56-60 in Watson, J.D. and J. Tooze, The DNA story: a documentary history of gene cloning. (San Francisco: Freeman, 1981.\" This version is from my uneditted ms. of \" #229. 230. Carhart, R.E., D.H. Smith, H. Brown and N.S. Sridharan, 1975. Applications of artificial intelligence for chemical inference. XVI. Computer generation of vertex-graphs and ring systems. J. Chem. Inform. Comp. Sci. 15:124-130. 231. Smith, Dennis, 1975. Applications of artificial intelligence for chemical inference. XVIII. The scope of structural isomerism. J. Chem. Inf. Comp. Sci. 15:203-207. 232. Dromey, R.G., M.J. Stefik, T.C. Rindfleisch and A.M. Duffield, 1976. Extraction of mass spectra free of background and neighboring component contributions from gas chromatography/mass spectrometry data. Anal. Chem. 48:1368-1375. 233. Shih, K. and J. Lederberg, 1976. Effects of chloramine on Bacillus subtilis DNA. J. Bact. 125:934-945. 234. Levinthal, E.C., R.E. Carhart, S.M. Johnson and J. Lederberg, 1975. When computers talk to computers. Industrial Research p. 35-42, November 15, 1975. 235. Buchanan, B.G., D.H. Smith, W.C. White, R. Gritter, E.A. Feigenbaum, J. Lederberg and C. Djerassi, 1976. Applications of artificial intelligence for chemical inference. XXII. Automatic rule formation in mass spectrometry by means of the meta-DENDRAL program. J. Am. Chem. Soc. 98:6168-6178. 236. Sagan, Carl and Joshua Lederberg, 1976. The prospects of life on Mars: pre-Viking assessment. Icarus 28:291-300. 237. Shih, K. and J. Lederberg, 1976. Chloramine mutagenesis in B. subtilis. Science 192:1141-1143. 238. Smith, D.H., J.P. Konopelski and C. Djerassi, 1976. Applications of artificial intelligence for chemical inference. XIX. Computer generation of ion structures. Org. Mass Spectrometry 11:86-100. 239. Carhart, R.E., S.M. Johnson, D.H. Smith, B.G. Buchanan, R.G. Dromey and J. Lederberg, 1975. Networking and a collaborative research community: a case study using the DENDRAL programs. pp. 192-217 in Peter Lykos (ed.) Computer Networking and Chemistry, ACS Symposium Series, No. 19. American Chemical Society. Washington. \" re SUMEX 240 Ehrlich S.D., Bursztyn-Pettegrew H., Stroynowski I., Lederberg J. Cloning of the thymidylate synthetase gene of the phage phi-3-T. Proceedings of the 10th Miles International Symposium (1976) in "Recombinant Molecules: impact on science and society" (R.F. Beers and E.G. Bassett, eds) Raven Press, NY 1977 241 Ehrlich S.D., Bursztyn-Pettegrew H., Stroynowski I., Lederberg J. Expression of the thymidylate synthetase gene of the B. subtilis bacteriophage phi-3-T in E. coli. Proc. Nat. Acad. Sci. 73:4145-4149 (1976). 242 Klein H.P., Lederberg J., Rich A., Oyama V.I., Levin G.V. The Viking Mission search for life on Mars. Nature (1976) 262:24-27 243 Klein H.P., Horowitz N.H., Levin G.V., Oyama V.I., Lederberg J., Rich A., Hubbard J.S., Hobby G.L., Straat P.A., Berdahl B.J., Carle G.C., Brown F.S., Johnson R.D. The Viking biological investigations: preliminary results. Science (1976) 194:99-105 244 Smith, D.H. and R.E. Carhart Structural isomerism of mono- and sesquiterpenoid skeletons. Tetrahedron (1976) 32:2513-2519 245 Lederberg, J. and H. Zuckerman From schizomycetes to bacterial sexuality - a case study of dis- continuity in science [unpublished] 246 Ehrlich, S.D. Replication and expression of plasmids from Staphylococcus aureus in Bacillus subtilis. Proc. Nat. Acad. Sci. (1977) 74:1680-1682 247 Lederberg, J. Foreword to Essays of an Information Scientist by E. Garfield ISI Press, PA, (1977), pages xi-xi Cf. Q-66 248 Mitchell, T.M. and G. M. Schwenzer Application of artificial intelligence for chemical inference XXV. A computer program for automated empirical 13C NMR formation 1977. 249 Chi, Ning-Yen W., S. D. Ehrlich, and J. Lederberg Functional Expression of Two Bacillus subtilis Chromosomal Genes in Escherichia coli. J. Bacteriology (1978), 133(2):816-821. 250 Ehrlich, S.D., V. Sgaramella, and J. Lederberg T4 Ligase joins flush-ended DNA duplexes generated by restriction endonucleases. In H.J. Vogel (ed) Nucleic Acid-Protein Recognition Academic Press, N.Y. (1977), pp. 261-268. 251 Harris-Warrick, R.M. and J. Lederberg Interspecies transformation in Bacillus I: Sequence heterology as the major barrier. J. Bacteriology (1978), 133(3):1237-1245. 251a Harris-Warrick, R.M. and J. Lederberg Interspecies transformation in Bacillus II: Mechanism of heterologous intergenote transformation. J. Bacteriology (1978), 133(3):1246-1253. 252 Sgaramella, V. and S. D. Ehrlich Use of the T4 Polynucleotide ligase in the joining of flush-ended DNA segments generated by restriction endonucleases. Eur. J. Bioch. (1978), 86(2):53l-537. 253 Lederberg, J. Digital communications and the conduct of science: The new literacy. Proc. of the IEEE (1978), 66(11):1314-1319. .ig also Human Systems Management. 1:29-37 (1980). .. 254 Elkana, Y., J. Lederberg, R.K. Merton, A. Thackray, and H. Zuckerman. (eds) Introduction in Toward a Metric of Science: The Advent of Science Indicators. John Wiley & Sons, (1978). 255 Lindsay, R.K., B.G. Buchanan, E. A. Feigenbaum and J. Lederberg Applications of Artificial Intelligence for Organic Chemistry: The Dendral Project. McGraw-Hill Book Co., (1980).; later Kaufmann 256 Feitelson, J.S. and J. Lederberg. Crude lysates of Staphylococcus aureus can transform Bacillus subtilis. J. General Microbiol., (1979), 116:545-547. 257 Lederberg, J. "Genetics" in Biology in Profile. Pergamon Press, (1981), pp. 101-105. 258 Lederberg, J. Comparative Toxicology, Environmental Health and National Productivity. Am. J. Med. (editorial), (1980). 259 Lederberg, J. Network New York. How does the scientific community communicate? The Sciences (Pub. by NYAS), (1980), pp. 6-8. 260 Lederberg, J. A Challenge for Toxicologists Regulatory Toxicol. and Pharmacol., (1981), 1:110-112. 261 Stroynowski, I.T. Distribution of Bacteriophage phi-3T Homologous Deoxyribonucleic Acid Sequences in Bacillus subtilis 168, Related Bacteriophages, and Other Bacillus Species. J. Bacteriology, 148:91-100, 1981. 262 Stroynowski, I.T. Integration of the Bacteriophage phi-3T-coded Thymidylate Synthetase Gene into the Bacillus subtilis Chromosome. J. Bacteriology, 148:101-108, 1981. 263 Lederberg, J. "Cycles and Fashions in Biomedical Research." pp. 202-216 in "Academic Medicine, present and future", Bowers, J.Z., and King, E.. E. (eds) (Conference held 25-27 May, 1982) Rockefeller Archive Ctr., North Tarrytown, N.Y. (1983) .ig with 1984 addendum on Limits to reductive explanation per Laplace. .. 264 Lederberg, J. Harnessing biomedical research to health needs. World Health Forum [WHO] 5(1):60-61 1984. 265 Lederberg, J. Toward a More Perfect Union: Science and Medicine. Proceedings of The National Health Constitutional Convention. Hahnemann University, October 24, 1983, Philadephia, Pa. 266. Lederberg, J. Forty Years of Genetic Recombination in Bacteria. A Fortieth Anniversary Reminiscence. Nature, 324:627-628 (1986) 267. Zuckerman, H. A. & Lederberg, J. Forty Years of Genetic Recombination in Bacteria. Postmature Scientific Discovery? Nature, 324:629-631 (1986) .ig erratum N 327: cited a few places! .. 268. Lederberg, J. Edward Lawrie Tatum. Biographical Memoirs, National Academy of Sciences. 59: 357-386 (1990). .ig See also 268.anb American National Biography; revised extract .. 268a Annual Review of Genetics, 13:1-5 (1979). Yearbook, Amer. Phil. Soc. (1977). 269. Lederberg, J. Genetic Recombination in Bacteria: A Discovery Account. Ann. Rev. Genet. 21:23-46 (1987) .ig also "The impact of basic research in genetic recombination. A personal account by Joshua Lederberg. Part 1. The Search for a Sexual Stage in Bacteria. Current Contents LS 31(24):4-17 (1988) 6/13. Part 2. A discovery recounted and evaluated. Current Contents LS 31(25):3-14 (1988) 6/20. . also pp. 893-915 in pt. 1, P273 . and "A tribute to my mentors." pp. 354-358 in Brandwein, P.F., Passow, A.H. (eds.) Gifted young in science: potential through performance. Nat Science Teachers Assn, Washington, 1989. .. 270. Lederberg, J. How DENDRAL was conceived and born. In ACM Conference on the History of Medical Informatics. pp. 5-24. Association for Computing Machinery, N.Y., 1987. . Held: NLM 11/5/87; (also SU KSL 87-54 8/87) also 14-44 in Blum, B.I. and Duncan, K. (eds). A history of medical informatics. ACM Press & Addison Wesley New York 1990. . see also discussion 45-47, 71-73, 111. 271. Lederberg, J. 1988 The Second Century of Louis Pasteur. a global agenda for biomedical research. pp. 19-30 in M. Schwartz (ed.) Molecular Biology and Infectious Diseases. Colloque du Centenaire de l'Institut Pasteur. 5-9 Oct. 1987 Paris Elsevier: Amsterdam. 271a. "Scientists must challenge today's common wisdom". The Scientist. July 11, 1988. 272 Terry lectures, Yale. -- to be given 1989. Apr 6 7 13 14 273 Excitement & Fascination of Science. Vol. III parts 1,2. compiled by Lederberg,J. 1990. Palo Alto, CA: Annual Reviews, Inc. v.1 1297 pp. + index pt. 2 1301-2338. 273a Introduction: Reflections on scientific biography. by JL pp. xvii-xxiv. . Also reprinted in Current Contents, 1990 #5 1/29/90 ; and EG Essays v. 13 274 Sputnik 1957-1987 The Scientist, 10/5/87 also published as "Sputnik + 30", Jour. Genetics (Indian. Acad. Sci.) 66:217-220 1987 275 Biomedical Science, Infectious Disease, and the unity of humankind. "Nobel" colloquium, Paris, Jan 1988. Mitterand-Wiesel JAMA 260 (5): 684-685 (1988) 8/5 .ig also Current Contents #21 3-5 (1989) May 22. .. 276 Bacterial Variation since Pasteur; Rummaging in the attic: antiquarian ideas of transmissible heredity, 1880-1940. ASM News 58(5): 261-265 (1992). .ig Bacterial Variation from Pasteur to Jacob. Colloque Histoire de l'Institut Pasteur June 1988 Publication abandoned 8/91 -- submitted to Burian,Pitt @VPI Accepted for ASM Newsletter 6/92 .. 277 JL: Does scientific progress come from projects or people? Reflections on the Project grant system. 11/9/87 NASULGC Reprinted in Current Contents (LS), 32(48): 4-12 (1989) 278 JL: Pandemic as a natural evolutionary phenomenon. New School Conference on Plagues. 1/88 Social Research 55 (3): 342-357 1988 . also pp 21-28 in: Mack, Arien (ed). In Time of Plague. The History and Social Consequences of Lethal Epidemic Disease. New York: NY University Press, 1991. . also pp. 3-20. "La pandemia come fenomeno evoluzionistico naturale" in Donghi, P. (ed) "La Medicina di Darwin" Bari: Laterza & figli, 1998 (Biblioteca di Cultura Moderna Laterza, BCM 1143). .also pp. 19-33 in "Human immunodeficiency viruses. Biology, Immunology and Molecular Biology. Nita Saksena, ed. Medical Systems SpA: Genoa, Italy. 279 The ontogeny of the clonal selection theory of antibody formation: Reflections on Darwin and Ehrlich: Ann. NYAS 546:175-187. 1988 280 [was Some provocative questions for cancer research] A biologist poses some questions about cancer. pp. 137-140 in Fortner,JG and Rhoads, JE (eds.) Accomplishments in Cancer Research 1987. 1987 Prize Year. General Motors Cancer Research Foundation. Phila. Lippincott 1988. [10/29/87 GM - Fortner symposium] 281 The Social Function of the Scientist. 1989 pp. 510-514 "1939 J.D. Bernal's The Social Function of Science 1989" H. Steiner ed. Akademie-Verlag Berlin. 282 History of Microbiology, 1930-1950. Enciclopedia Italiana "vicennium" Cf. revision for Encyclopedia of Microbiology [P-291 ] 283 Plasmid (1952-1997). Plasmid 1:1-9 (1998) . -- SEE SAM-320; T-16 284 ASM contribution: ?? Salmonella 157A Gene. Enc. Americana 1988: done 4/12/88 285 JL Retrospection on P27 See P/27x Replica plating and indirect selection of bacterial mutants; Isolation of preadaptive mutants in bacteria by sib selection. Genetics 121:395-399. (1989) 286 JL 1993. Genetic Maps -- fruit flies, people, bacteria, and molecules. A tribute to Morgan and Sturtevant. pp. 26-49. in The Biological Century. Friday evening talks at the Marine Biological Laboratory. Edited by R. B. Barlow, J. Dowling and G. Weissmann. Cambridge Mass: Harvard Univ. Press \" was SAM/300. 8/15/88 talk. 287 Buchanan, B.G., Feigenbaum, E.A. and Lederberg, J. Invited comments: On Gray's interpretation of the Dendral project and programs: myth or mythunderstanding? Chemometrics and Intelligent Laboratory Systems, 5:33-35, 1988. .ig cf: Gray, N.A.B. Dendral and meta-dendral -- the myth and the reality. Chemometrics and Intelligent Laboratory Systems, 5:33-35, 1988. Gray, N.A.B. Response to comments by Buchanan, Feigenbaum and Lederberg. Chemometrics and Intelligent Laboratory Systems, 5:33-35, 1988. .. 288 T/8 emerging viruses. Washington 5/1/89 revised 12/89 VIRUSES AND HUMANKIND: INTRACELLULAR SYMBIOSIS AND EVOLUTIONARY COMPETITION in Morse, S. (Oxford Univ. Press) dupl. as P-295 289 Lindsay, Robert K., Buchanan, Bruce G., Feigenbaum, Edward A. and Lederberg, Joshua. Dendral: A Case Study of the First Expert System for Scientific Hypothesis Formation. Artificial Intelligence 61(2): 209-261, 1993. 290 JL. The gene (H. J. Muller 1947). Genetics 129:313-316 (1991). also reprinted, with preface by E. Garfield, in Current Contents 34(7): 3-11 (1992). \"Perspective for Genetics. Was T/10 291 JL (Ed. in chief). Encyclopedia of Microbiology. 4 vols. Academic Press San Diego 1992 was T/14 291b. History of Microbiology, Milton Wainright and JL. pp. 419-437 292 JL 1993 What the double helix (1953) has meant for basic biomedical science. A personal commentary. JAMA 269(15): 1981-1985. \" was T-46. Also in P-299 \" also pp. 15-26, in The philosophy and history of \" molecular biology: new perspectives. S. Sarkar, ed/. \" Kluwer: Dordrecht 293 JL Crowded at the summit: emergent infections and the global food chain. ASM News 59(4): 162-163 (1993). \" was T-47 also: "AIDS pandemic provokes alarming reassessments of infectious disease." The Scientist. July 12, 1993. p. 11 and: "Emerging infections: microbial threats to health." Trends in Microbiology. 1(2):43-44 (1993). . 293b JL Emerging infections: private concerns and public responses. ASM News 60(5): 233. 1994. 294 JL The anti-expert system: hypotheses an AI program should have seen through. pp 459-463. in L. Hunter ed. Artificial Intelligence and Molecular Biology AAAI Press, Menlo Park CA 1993 .ig also Foreword, ix-x AAAI - AI & Mol Biol. - Stanford SU March 27-29 1990 Was T-15 .. 295 JL Viruses and Humankind: Intracellular Symbiosis and Evolutionary Competition. pp 3-9. in Morse, Stephen S.(ed). Emerging Viruses. NY: Oxford University Press, 1993. [[[ See P-288 \" was T-31 296 JL- Continuing confusion. [re social status and sex ratio] Nature 1993 2:8. \" was T-51 297 JL 1994 The transformation of genetics by DNA: An anniversary celebration of Avery, MacLeod and McCarty, 1944. Genetics 136(2): 423-426. \" was T-12.gen also, Honoring Avery, Macleod, and Mccarty - The Team That Transformed Genetics SCIENTIST 1994, Vol 8, Iss 4, pp 11+ 298 Jon Wolff & JL. 1994 A history of gene transfer and therapy. pp. 3-25 in Gene Therapeutics: Methods and applications of direct gene transfer. Jon A. Wolff, ed. Boston: Birkhaueser 1994 . Human Gene Therapy. 5:469-480 1994 was T-45 : 299 JL: Greetings, in Chambers, D.A. ed. DNA: the Double Helix. Perspective and Prospective at 40 years. Ann. NYAS 758:176-179 1995 .ig 40th Anniv of Watson and Crick 1953 @ Chicago. was T-54 .. 300 JL. See TX-5 Stanford Symposium "Notes on systematic hypothesis generation, and application to disciplined brainstorming" 1995 AAAI Symposium March 27, 1995 [NA] Technical Report SS-95-03 301a JL. JAMA 275: 243-245 1/17/ 1996 Infection emergent [T-84] 301b JL. JAMA 276: 417-418 8/7/96 Infectious disease -- a threat to global health and security. [T-93] 301c Annette Flanagin and JL. JAMA 276: 419-420 8/7/96. The threat of biological weapons == prophylaxis and mitigation. [T-93] Call for Papers. 301d JL. JAMA 278: 435-436 8/6/97. Infectious Disease and biological weapons : prophylaxis and mitigation. . "Biological Weapons: Limiting the Threat" MIT Press 1998 302 JL Smaller Fleas ... ad infinitum: Therapeutic bacteriophage redux. PNAS 93:3167-3168 (1996) 303 JL and others. was T-26 London 10/16/89 RSM symposium on creativity and discovery in medical science. cf Roy Soc Med; O'Reilly; McNaughton Published Creativity Research Journal, (1994). 7(3-4):223-224 . Booth C Lederberg J Introductions to the Meeting of the Royal-Society-of-Medicine. CREATIVITY RES J 1994;7(3-4):223-224 . Douglas B, Gruber H, Holmes F, Huxley A, Sela M, Lederberg J, Waelsch S, Booth C, Blumberg B, Aspects of Scientific Discovery - Aesthetics and Cognition - CREATIVITY RES J 1994;7(3-4):407-411 304 JL. D-Lib Magazine, May 1996 ISSN 1082-9873 URL=: http://www.dlib.org Options for the Future Symposium on electronic publishing, ICSU/UNESCO February 22, 1996 Paris, France also by ICSU "Electronic publishing in science", D Shaw and H Moore, eds. ICSU press, 1996; also: www.lmcp.jussieu.fr/icsu/information/proc_0296/; www.grainger.uiuc.edu/ .ig perhaps by Daedalus Cf Gordon Conference 1997; Peter Goldie - Lightbinders .. 305 JL Genetic recombination in Escherichia coli: Disputation at Cold Spring Harbor, 1946-1996. Genetics 144:439-443 (1996) \" Was T-85 306 Some early stirrings (1950 ff) of concern about environmental mutagens. Env Mol Mutagenesis 30:3-10 (1997). (Env Mutagen Soc., Minneapolis, Apr 20 1997) \" See T/99 306.tape Videotape of my address 307** New School of Social Research. Technology and Culture. Jan 17 1997 Arien Mack T-100 JL Science and technology; Biology and Biotechnology Social Research: 64:1157-1161 308** Infectious Disease as an Evolutionary Paradigm [Emerging Infectious Diseases * Volume 3 * Number 4 * October - December 1997] pp 417-423 . This text is also available online - URL: ftp://ftp.cdc.gov/pub/EID/vol3no4/ascii/lederber.txt http://www.cdc.gov/ncidod/EID/eid.htm 309** Emerging Infections: An evolutionary perspective. March 8, 1998. International Conference on EID Emerging Infectious Diseases, 4(3): 366-371 (1998) http://www.cdc.gov/ncidod/EID/vol4no3/lederberg.htm 310** The future of infectious disease. PP. 5-14 in Singhal, RA and Sood, O.P. (eds) Drug Resistance: mechanisms and management. Rambaxy Science Foundation, 4th Annual Symposium. New Delhi Nov. 1997 New Delhi: Communicore 311** Lederberg, J. Escherichia coli. pp. 230-232 in Instruments of Science. An Historical Encyclopedia Robert Bud and Deborah Jean Warner, editors. New York: Garland Publishing, Inc., 1998 .. was T-67 312** The future of infectious diseases. Journal of Urban Health, 75: 463-470. (NYAM symposiumn June 5 1995)