Pest Management & Biological Control Research Unit

Education:

B.S. Biochemistry, Kansas State University 1995

Ph.D. Biochemistry, Kansas State University 2003

Research Interests:

My research interests include understanding various molecular, biochemical and physiological functions in insects, including Bt mode-of-action and receptor function, insecticide/Bt resistance, digestive biochemistry and physiology, immunity, and parasitoid/host interactions. My current interest involves the study of properties and function of Bt-binding cadherin receptor proteins from various insects, including the cotton pest insect Pectinophora gossypiella (pink bollworm).  I am also active in understanding the digestive physiology and water transport proteins in other cotton pests, including Lygus hesperus and Bemisia tabaci.

Fabrick, J.A. and Tabashnik, B.E. 2007. Binding of Bacillus thuringiensis toxin Cry1Ac to multiple sites of cadherin in pink bollworm.  Insect Biochem. Mol. Biol. 37(2): 97-106.

Dennehy, T.J., DeGain, B.A., Harpold, V.S., Brown, J.K., Morin, S., Fabrick, J.A., Byrne, F.J., Nichols, R.L. 2006. New challenges to management of whitefly resistance to insecticides in Arizona. The University of Arizona, College of Agriculture Vegetable Report, Series P-144. Available online: http://cals.arizona.edu/pubs/crops/az1382/.

Tabashnik, B.E., Biggs, R.W., Fabrick, J.A., Gassmann, A.J., Dennehy, T.J., Carriere, Y., Morin, S. 2006.  High-level resistance to Bt toxin Cry1Ac and cadherin genotype in pink bollworm.  J. Econ. Entomol. 99(6): 2125-2131.

Tabashnik, B.E., Fabrick, J.A., Henderson, S., Biggs, R.W., Yafuso, C.M., Nyboer, M.E., Manhardt, N.M., Coughlin, L.A., Sollome, J., Carriere, Y., Dennehy, T.J., Morin, S. 2006.  DNA screening reveals pink bollworm resistance to Bt cotton remains rare after a decade of exposure.  J. Econ. Entomol. 99(5): 1525-1530.

Fabrick, J.A., Baker, J.E., and Kanost, M.R. 2004.  Innate immunity in a Pyralid moth: Functional evaluation of domains from a beta-1,3-glucan recognition protein.  J. Biol. Chem. 279(25): 26605-26611.

Morin, S., Henderson, S., Fabrick, J.A., Carrière, Y., Dennehy, T.J., Brown, J.K., Tabashnik, B.E. 2004.  DNA-based detection of Bt resistance alleles in pink bollworm.  Insect Biochem. Mol. Biol. 34: 1225-1233.

Fabrick, J.A., Baker, J.E., and Kanost, M.R. 2003.  cDNA cloning, purification, properties, and function of a beta-1,3-glucan recognition protein from a pyralid moth, Plodia interpunctella.  Insect Biochem. Mol. Biol. 33: 579-594.

Baker, J.E. and Fabrick, J.A. 2002.  Unusual responses of Indianmeal moth larvae to envenomation and parasitization by a braconid ectoparasitoid.  J. Entomol. Sci.  37(4): 370-374.

Fabrick, J.A., Behnke, C., Czapla, T., Bala, K., Rao, A.G., Kramer, K.J., and Reeck, G.R. 2002.  Effects of a potato cysteine proteinase inhibitor on midgut proteolytic enzyme activity and growth of the southern corn rootworm, Diabrotica undecimpunctata howardi (Coleoptera: Chrysomelidae).  Insect Biochem. Mol. Biol. 32(4): 405-415.

Perez-Mendoza, J., Dowell, F.E., Broce, A.B., Throne, J.E., Wirtz, R.A., Xie, F., Fabrick, J.A., and Baker, J.E. 2002.  Chronological age-grading of house flies by using near-infared spectroscopy.  J. Med. Entomol. 39(3): 499-508.

Yu, X.Q., Zhu, Y., Ma, C., Fabrick, J.A., and Kanost, M.R. 2002.  Pattern recognition proteins in Manduca sexta plasma.  Insect Biochem. Mol. Biol. 32(10): 1287-1293.