Biography:
Publications
Guo, H. B.; Guo, H. Histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 8797-8802.
Xu, Q.#; Guo, H. B.#; Wlodawer, A.; Nakayama, T.; Guo, H. The QM/MM molecular dynamics and free energy simulations of the acylation reaction catalyzed by the serine carboxyl peptidase kumamolisin-As. Biochemistry 2007, 46, 3784-3792. # indicates the authors who contributed equally to the work.
Guo, H. B.; Wlodawer, A.; Nakayama, T.; Xu, Q.; Guo, H. Catalytic role of proton transfers in the formation of a tetrahedral adduct in a serine carboxyl peptidase. Biochemistry 2006, 45, 9129-9137.
Guo, H. B.; Wlodawer, A.; Guo, H. A general acid-base mechanism for the stabilization of a tetrahedral adduct in a serine-carboxyl peptidase: A computational study. J. Am. Chem. Soc. 2005, 127, 15662-15663.
Guo, H. B.; Rao, N.; Xu, Q.; Guo, H. Origin of tight binding of a near-perfect transition-state analog by cytidine deaminase: Implications for enzyme catalysis. J. Am. Chem. Soc. 2005, 127, 3191-3197.
Guo, H. B.; Beahm, R. F.; Guo, H. Stabilization and destabilization of the Cδ–H…O=C hydrogen bonds involving proline residues in helices. J. Phys. Chem. B 2004, 108, 18065-18072.
Guo, H. B.; Zhang, F.; Wu, G. S.; Sun, F.; Pu, S.; Mai, X.; Qi, G. Multi-wavelength optical storage of diarylethene PMMA film. Opt. Mater. 2003, 22, 269-274.
Zhang, F.; Guo, H. B.; Pu, S.; Sun, F.; Zhou, X.; Yuan, P.; Xu, D.; Qi, G. Diaryethene materials for photon mode optical storage. Proc. (Review article). SPIE 2002, 4930, 93-104.
Guo, H. B.; Zhang, F.; Tang, Y.; Zhao, F.; Wu, G. S. Novel nondestructive readout method for rewritable storage systems of diarylethene photochromic molecules. Proc. SPIE 2001, 4085, 158-161.
Guo, H. B.; Zhou, X. G. Several laws in parabolic motions. Phys. Bull. (China) 1993, Iss. 9, 24-27.
Education:
- 01/2008~ Postdoctoral research associate, Oak Ridge National Lab, with Prof. Jeremy C. Smith.
- 12/2003-12/2007. Postdoctoral research associate, University of Tennessee, Knoxville, with Prof. Hong Guo.
- 09/1997-01/2003. Ph.D. in Physical Chemistry: Tsinghua University, Beijing, China. Advisor: Prof. Guo-Shi Wu.
- 09/1993-07/1997. B.S. in Chemistry: Tsinghua University, Beijing, China.
