Plasmodium species |
Stages found in blood |
Appearance of Erythrocyte (RBC) |
Appearance of Parasite |
P. falciparum Images |
Ring Images |
normal;
multiple infection of RBC more common than in other species; Maurer's
clefts (under certain staining conditions) |
delicate
cytoplasm; 1 to 2 small chromatin dots; occasional appliqué (accolé) forms |
Trophozoite Images |
normal;
rarely, Maurer's clefts (under certain staining conditions) |
seldom
seen in peripheral blood; compact cytoplasm; dark pigment |
Schizont Images |
normal;
rarely, Maurer's clefts (under certain staining conditions) |
seldom
seen in peripheral blood; mature = 8 to 24 small merozoites; dark pigment, clumped in one
mass |
Gametocyte Images |
distorted
by parasite |
crescent
or sausage shape; chromatin in a single mass (macrogametocyte) or diffuse
(microgametocyte); dark pigment mass |
P. vivax Images |
Ring Images |
normal
to 1.25×, round; occasionally fine Schüffner's dots; multiple infection of
RBC not uncommon |
large
cytoplasm with occasional pseudopods; large chromatin dot |
Trophozoite
Images |
enlarged
1.5
to 2×; may be distorted; fine Schüffner's dots |
large
amoeboid cytoplasm; large chromatin; fine, yellowish-brown pigment |
Schizont Images |
enlarged
1.5
to
2×; may be distorted; fine Schüffner's dots |
large,
may almost fill RBC; mature = 12 to 24 merozoites; yellowish-brown, coalesced pigment |
Gametocyte
Images |
enlarged
1.5
to 2×; may be distorted; fine Schüffner's dots |
round
to oval; compact; may almost fill RBC; chromatin compact, eccentric (macrogametocyte) or
diffuse (microgametocyte); scattered brown pigment |
P. ovale Images |
Ring Images |
normal
to 1.25×, round to oval; occasionally Schüffner's dots; occasionally fimbriated;
multiple infection of RBC not uncommon |
sturdy
cytoplasm; large chromatin |
Trophozoite
Images |
normal
to 1.25×; round to oval; some fimbriated; Schüffner's dots |
compact
with large chromatin; dark-brown pigment |
Schizont Images |
normal
to 1.25×, round to oval, some fimbriated, Schüffner's dots |
mature
= 6 to 14 merozoites with large nuclei, clustered around mass of dark-brown pigment |
Gametocyte
Images |
normal
to 1.25×; round to oval, some fimbriated; Schüffner's dots |
round
to oval; compact; may almost fill RBC; chromatin compact, eccentric (macrogametocyte) or
more diffuse (microgametocyte); scattered brown pigment |
P.
malariae Images |
Ring
Images |
normal to 0.75× |
sturdy
cytoplasm; large chromatin |
Trophozoite Images |
normal
to 0.75×; rarely, Ziemann's stippling (under certain staining conditions) |
compact
cytoplasm; large chromatin; occasional band forms; coarse, dark-brown pigment |
Schizont
Images |
normal
to 0.75×; rarely, Ziemann's stippling (under certain staining conditions) |
mature
= 6 to 12 merozoites with large nuclei, clustered around mass of coarse, dark-brown pigment;
occasional rosettes |
Gametocyte
Images |
normal
to 0.75×; rarely, Ziemann's stippling (under certain staining conditions) |
round
to oval; compact; may almost fill RBC; chromatin compact, eccentric (macrogametocyte) or
more diffuse (microgametocyte); scattered brown pigment |
P. knowlesi
Images |
Ring
Images |
normal to 0.75×; multiple infection not uncommon. |
delicate cytoplasm; 1 to 2 prominent chromatin dots; occasional appliqué (accolé) forms |
Trophozoite
Images |
normal
to 0.75×; rarely, Sinton and Mulligan's stippling (under certain staining conditions) |
compact
cytoplasm; large chromatin; occasional band forms; coarse, dark-brown pigment |
Schizont
Images |
normal
to 0.75×; rarely, Sinton and Mulligan's stippling (under certain staining conditions) |
mature = up to 16 merozoites with large nuclei, clustered around mass of coarse, dark-brown pigment;
occasional rosettes; mature merozoites appear segmented |
Gametocyte
Images |
normal
to 0.75×; rarely, Sinton and Mulligan's stippling (under certain staining conditions) |
round
to oval; compact; may almost fill RBC; chromatin compact, eccentric (macrogametocyte) or
more diffuse (microgametocyte); scattered brown pigment |