Cancer Genome Anatomy Project

Protein Motifs & Non-Synonymous cSNP Subsitution Prediction Acc: NM_004333.2   766 aa

To view SNPs in 3D Structures Click on the below

	Model	PfamID	Domain	From	To	AA Prediction
						SNP	%Score	LogE	Deleterious
	Pkinase	PF00069.15	1-1	457	714
	SNPID:  2417553					V600E	-0.3494	0.3010
	Pkinase_Tyr	PF07714.6	1-1	457	714
	SNPID:  2417553					V600E	0.0000	0.0000

* Deleterious substitutions are predicted using LogE threshold >=1.0. For additional information please click here

Motifs:  2

Solid : Single domain	Striped : Shared domain	Red : Predicted Intolerant	Blue : Predicted Tolerant	Gray : Not Analyzed