Curriculum Vitae

 

 

 

MARK STORK GEORGE, M.D.

 

 

 

OFFICE ADDRESS:           Room 502 North, Department of Psychiatry

                                                MUSC, IOP, 67 President Street

                                                Charleston, SC 29425-0720

                                                Telephone: (843) 792-7750

                                                FAX: (843) 792-5702

                                                E-mail: georgem@musc.edu

                                               

PROFESSIONAL LICENSURE:

 

   Diplomate, Neurology, (Board Certification #36575), American Board of Psychiatry and Neurology

            (November, 1992).                                     

 

   Diplomate, Psychiatry, (Board Certification #38811), American Board of Psychiatry and Neurology

            (January, 1994).

      

   South Carolina State Board of Medical Examiners #13093

 

   Limited License, General Medical Council, United Kingdom, (1990-1991)

 

 

EDUCATION: 

 

  1980                              A.B.  (1980) (Philosophy, cum laude), Davidson College, Davidson, NC

 

  1980 - 1981    South Carolina College (The Honors College), University of South Carolina, Columbia,S.C. (Pre-medical courses in biology, physics, chemistry)

 

  1985                M.D. (1985) Medical University of South Carolina (MUSC),  Charleston, SC

 

 

PROFESSIONAL EXPERIENCE:

 

 2000 - present              University Distinguished Professor (Awarded by MUSC Board of Trustees, 9/01),

                                        Departments of Psychiatry, Radiology and Neurology,

                                        Medical University of South Carolina (MUSC) (With tenure, 1997).

  2000 - present             Director, MUSC Center for Advanced Imaging Research (CAIR)

  2000 – present            Director, Specialty Division, MUSC Psychiatry Department

  1996 - present             Director, Brain Stimulation Laboratory, MUSC

  1996 - present             Director, Psychiatric Neuroimaging, Ralph H. Johnson VA Medical Center, Charleston

  2002- present              Adjunct Professor of Psychology, College of Liberal Arts, University of South Carolina

  2003- present              Statewide Co-director and MUSC Director, SC Statewide Brain Imaging Center of Excellence

 

  1999 - 2000                  Professor, Departments of Psychiatry, Radiology and Neurology

  1995 - 2000                  Director, Functional Neuroimaging Research Division, Psychiatry Department, MUSC.

  1995 - 1998                  Associate Professor, Departments of Psychiatry, Radiology and Neurology

  1995 - 1997                  Adjunct Professor/ Visiting Scientist, Biological Psychiatry Branch, NIMH.

  1991 - 1995                  Senior Staff Fellow, Biological Psychiatry Branch, National Institute of Mental Health,

                                        Bethesda, MD

  1990 - 1991                  Visiting Research Fellow, Raymond Way Neuropsychiatry Research Group, Institute of                                          Neurology, Queen Square, London, England

  1990 - 1991                  Senior Registrar (Honorary), The National Hospital for Neurology and Neurosurgery,

                                        Queen Square, London

  1990 - 1991                  Trainee, Institute of Nuclear Medicine, University College of London and Middlesex School of Medicine, London

  1989 - 1991                  Clinical Instructor, Neurology and Psychiatry, MUSC

  1989 - 1990                  Chief Resident, Neurology, MUSC

  1986 - 1990                  Resident, Combined Neurology and Psychiatry Program, MUSC

  1985 - 1986                  Intern (Medicine, Neurology and Psychiatry), MUSC

 

 

SUPPLEMENTAL TRAINING:

 

            Advanced Cardiac Life Support - approved, Charleston, S.C., September, 1989.

Nuclear Medicine 'Core of Knowledge' - Royal College of Nuclear Medicine, Course Given at the Royal Free Hospital, London, October, 1990.

Statistics 500M - Statistics for Biomedical Scientists, Fall, 1991, Foundation for Advanced Education in the Sciences, Inc.(FAES), NIH    Biochemistry 533M - The Molecular and Cellular Basis of Intercellular                 Communication, Fall, 1992, FAES, NIH

            Computers 319 - Introduction to UNIX, Fall, 1992, FAES, NIH

 

 

OTHER WORK EXPERIENCE:

 

  1982 - 1983    (Summers)  Salmon Fisherman based in Kodiak, Alaska  

  1980 - 1981    Graduate Assistant, USC Philosophy Department

  1976 - 1979    Staff Writer for The Davidson Update, Davidson NC

  1977 - 1979    (Summers) Staff Writer for The State Newspaper, Columbia SC

1976   (Summer) Runway Striper, The S.C. Aeronautics Commission

 

MEMBERSHIPS, PROFESSIONAL ORGANIZATIONS:

 

            Alpha Omega Alpha (elected 3/00)

            Academy of Psychosomatic Medicine, American Academy of Neurology

            American Association for the Advancement of Science

            American Association for the Study of Headache

            American College of Neuropsychopharmacology (ACNP) (Full Member, 1999)

            American Medical Association, American Neuropsychiatric Association

            American Psychiatric Association, Association for Academic Psychiatry

            Behavioral Neurology Society, British Neuropsychiatry Association (visiting)

            Charleston County Medical Society, International Society for the History of Neurosciences

            International Society for Neuroimaging in Psychiatry, Society of Biological Psychiatry

            Society for Neuroscience, South Carolina Medical Society

            South Carolina Psychiatric Association, Southern Association for Research in Psychiatry

 

SCIENTIFIC, EDITORIAL AND MEDICAL ADVISORY BOARDS:

 

            Member, American Psychiatric Association, Council on Research,

                          Committee on Research Training (1994-2001).

            Member, American Psychiatric Association, Council on Research, Committee on ECT and other

                       Electromagnetic Brain Treatments  (2001- present).

            Chairperson, The rTMS Depression Consortium (6/96 - present)

            The International Autistic Research Organisation (U.K.)(1991 - present).

 

            Editor, North America, Human Psychopharmacology: Clinical and Experimental (1995 - 1999).

 

            Guest Editor:                  Psychiatric Annals, 1994: 24,12

                                                      'The Emerging Neuroanatomy of Depression'

                                                     CNS Spectrums 1997:2

                                                      'Transcranial Magnetic Stimulation - A Neuropsychiatric Tool for the 21st Century'

                                                     Primary Psychiatry 1998: 5

                                                     “Advances in Brain Imaging: What the Primary Psychiatrist Needs to Know”

                                                     Epilepsy and Behavior, 2001

                                                     “Neurostimulation and Neuropsychiatric Disorders”

                                                     Journal of ECT, 2002

                                                     “Advances in Brain Stimulation”

 

            Editorial Board:              Biological Psychiatry

                                                     Current Review of Mood Disorders

                                                     CNS Spectrums: The International Journal  of Neuropsychiatric Medicine   

 

            Industry Advisory Boards:      

                                                     Cyberonics Depression Scientific Advisory Board (6/01  - present)

                                                     Cyberonics Neuroscience Advisory Board (11/01 – present)

                                                     Neuronetics Depression Advisory Board (9/01 – present)

                                                     Depression Clinical Trial Steering Committee Member, Neuronetics (2003-present)                         

                                                    

                                                    

REVIEWER, JOURNALS:

 

            American Journal of Psychiatry; Anxiety and Depression; Archives of General Psychiatry; Brain; Biological Psychiatry; Bipolar Disorders: An International Journal of Psychiatry and Neurosciences; Convulsive Therapy; Depression and Anxiety; Human Psychopharmacology: Clinical and Experimental; International Journal of Neuropsychopharmacology;  Clinical Neurophysiology; Journal of Abnormal Psychology; Journal of Affective Disorders, Journal of Nervous and Mental Disease; Journal of Neuroimaging; Journal of Neuropsychiatry and Clinical Neurosciences; Journal of Theoretical Biology; Neurology; Neuropsychiatry, Neuropsychology and Behavioral Neurology; Neuroscience; Psychiatry Research; Psychological Medicine; Psychosomatics; Radiology; Science; Schizophrenia Research; The European Journal of Neuroscience; Trends in Cognitive Neuroscience.

 

REVIEWER, GRANTS:

 

            Ad Hoc Reviewer: The Ontario Mental Health Foundation, VA Merit Reviews, National Institute on Drug Abuse, National Institute of Mental Health, NINDS, National Science Foundation, Human Frontiers in Science Program, Canada Medical Research Council, UK MRC.

 

PUBLICATIONS

 

Letters:

 

 1.        George MS: Neuroscience and Psychiatry. Am J Psychiatry 1987;        144(8):1103.

 

 2.        George MS, Melvin JA, Mossman D: Mental illness and creativity. Am J Psychiatry  1988; 145(8):908.

 

 3.        Lydiard RB, George MS: Fluoxetine-related anorgasmy. So Med J 1989; 82(7):933-34.

 

 4.        George MS, Brewerton TD, Cochrane C: Trichotillomania and bulimia. N Engl J Med 1990;      322(7):470-471.

 

 5.        George MS, Pickett JB, Kohli H, Allison MA, Pritchard P: Paroxysmal Dystonic Reflex Choreoathetosis after minor closed head injury. The Lancet 1990; 336:1134-1135.

 

 6.        George MS, Kellner CH, Scott T, Malcolm R: Septum Pellucidum in schizophrenia (reply).  J Neuropsychiatry Clin Neurosci 1990; 2(4):462.

 

 7.        Kellner CH, Burns C, Bernstein C, Monroe R, George MS: Safe administration of ECT in a patient with a calcified frontal mass.  J Neuropsychiatry Clin Neurosci 1991; 3(3):353-354.

 

 8.        George MS, Post RM, Ketter T, Marengall L, Pazzaglia P: Alpidem as an antidepressant: clarification.  J Clin Psychiatry, 1992; 53(2):68.

 

 9.        Kellner CH, George MS, Burns C, Bernstein H, Rubey R, Custer J, Brewerton T: Human equivalent of canine acral lick. The Lancet 1992; 339:553.

 

10.       George MS, Trimble MR: Dystonia associated with fluvoxamine.  J Clin Psychopharm 1993; 13:220-221.

 

11.       George MS, Trimble MR: A fluvoxamine-induced frontal lobe syndrome in an obsessive compulsive patient. J Clin Psychiatry 1992; 53(10):379.

 

12.       Brewerton TD, George MS, Harden RN: Migraine and the eating disorders. Psychiatry Res 1993; 46;201-202.

 

13.       Ketter TA, Andreason PJ, George MS, Lee C, Gill DS, Parekh PI, Willis MW, Herscovitch P, Post RM:            Reply to Sarvay SM re: Procaine and Anterior Paralimbic CBF changes. Archives of General Psychiatry    1997:54, 8:764-765.

 

14.          George MS, Wassermann EM, Williams WE, Kimbrell TA, Little JT, Hallett M, Post RM: Reply to re: Mood Improvements Following Daily Left Prefrontal Repetitive Transcranial Magnetic Stimulation in Patients with Depression. American Journal of Psychiatry 1999: 156,4: 669-670.

 

15.          Anton R, George MS, Myrick H, Drobes D: Reply to re: Activation of Prefrontal Cortex and Anterior Thalamus in Alcoholic Subjects on Exposure to Alcohol-Specific Cues. Archives  2001, In Press.

 

16.          Kimbrell TA, Ketter TA, George MS, Little JT, Benson BE, Willis MW, Herscovitch P, Post RM: Reply to ‘Regional cerebral glucose utilization in patients with a range of severities of unipolar depression. Biol Psychiatry 2002, In Press.

 

Articles:

 

1987 

 

 1.        George MS, Taylor R, Seay AR, Hogan EL: Sydenham's Chorea: A disease on the increase?  J South Carolina Med Assoc 1987;83:523-527.

 

1989

 

 2.        George MS, Kellner CH, Fossey M:  Obsessive-compulsive disorder in a patient with MS. J Nerv Ment Dis 1989;177:304-5.

 

 3.        George MS, Scott T, Kellner CK, Malcolm R: Abnormalities of the septum pellucidum in schizophrenia: Two case reports and a discussion. J Neuropsychiatry Clin Neurosci 1989;1:385-390.                

 

 4.        George MS, Lydiard RB: Case report: Inability to walk as a symptom of panic disorder. Neuropsychiatry, Neuropsychol Behav Neurol 1989;2(3):219-223.

 

1990

 

 5.        George MS:  Doing a combined residency. JAMA 1990;263:1628.

 

 6.        George MS, Mcleod-Bryant S, Lydiard RB, Kurent JE, Zealberg J: Panic attacks and agoraphobia associated with a giant right cerebral arteriovenous malformation.  Neuropsychiatry, Neuropsychol Behav Neurol 1990;3(3):206-212.

                                                          

 7.        George MS, Gross JA, Hogan EL, Kurent J, Plyler J, Perot PL: Establishing brain death in South Carolina: A clinician's guide. J South Carolina Med Assoc 1990;86(7):385-388.

 

 8.        Brewerton TD, George MS:  The seasonal variation of migraine.  Headache 1990;30(8):511-513.

 

1991

 

 9.        George MS: Establishing brain death: The potential role of nuclear medicine in the search for a reliable confirmatory test. Eur J Nuclear Med 1991;18:75-77.

 

10.       Ring HA, George MS, Costa DC, Ell PJ: The use of neuropsychiatric activation procedures with single photon emission tomography: a review. Eur J Nuclear Med 1991;18:133-141.

 

11.       George MS: Obsessive Compulsive Disorder. Int Clin Psychopharmacol 1991;6:57S-68S.

 

12.       George MS, Lydiard RB: Speed of onset of action of the newer antidepressants: fluoxetine and buproprion. Int Clin Psychopharmacol, 1991, 6:209-217.

 

 

1992

 

13.       George MS, Melvin JA, Kellner CH: Obsessive-compulsive symptoms in neurologic disease: A review.  Behav Neurol 1992;5:19-30.

 

14.           George MS, Trimble MR: The changing 19th century view of epilepsy as reflected in the West Riding

           Lunatic Asylum Medical Reports, 1871-1877, vols 1-6. Neurology 1992;42:246-249.

 

15.       George MS: Early theories about the etiology of cerebral palsy: William Little and Sigmund Freud. J Hist Neurosci 1992;1:29-37.

 

16.       George MS, Ballenger JC: The neuroanatomy of panic disorder: The role of the right parahippocampal region. J Anxiety Disord, 1992;6:181-188.

 

17.       George MS, Ring HA, Costa DC, Kouris K, Ell PJ: Demonstration of Human Motor Cortex Activity Using SPECT.  J Neural Transm, 1992, 87,3:231-236.

 

18.       George MS, Costa DC, Kouris K, Ring HA, Ell PJ: Cerebral Blood Flow Abnormalities in Adults with Infantile Autism. J Nerv Ment Dis, 1992, 180, 7:413-417.

 

19.       Ring HA, Trimble MR, Costa DC, George MS, Verhoeff P, Ell PJ: Effect of vigabatrin on striatal dopamine receptors: Evidence in humans for interactions of GABA and dopamine systems. J Neurol, Neurosurg, Psychiatry, 1992, 55:758-761.

 

20.       George MS, Trimble MR, Costa DC, Robertson MM, Ell PJ: Elevated Frontal Cerebral Blood Flow in Gilles de la Tourette Syndrome (GTS): A 99Tcm-HMPAO SPECT Study. Psychiatry Research - Neuroimaging, 1992, 45:143-151. 

 

1993

 

21.       George MS, Trimble MR, Ring HA, Sallee FR, Robertson MM: Obsessions in Obsessive-Compulsive Disorder (OCD) With and Without Gilles de la Tourette Syndrome (GTS). Am J Psychiatry, 1993, 150: 93-97.

 

22.       George MS: A New Look at Obsessive-Compulsive Disorder and Gilles de la Tourette Syndrome. Clinical      Advances in the Treatment of Psychiatric Disorders., 1993, 7:1-12.*

 

23.       Brewerton TD, George MS: Is Migraine Related to the Eating Disorders?  Int J Eating Disord 1993, 14:75-79.

 

24.       Scott TF, Price TR, George MS, Brillman J, Rothfus W: Midline Cerebral Malformations and   Schizophrenia. J Neuropsychiatry and Clinical Neurosciences 1993, 5:287-293.

 

25.       George MS, Brewerton TD, Harden RN: Bulimia nervosa in outpatients with migraine. J Nervous Mental        Disease 1993, 181;11:704-706. 

 

26.       George MS, Ketter TA, Gill D, Haxby JV, Ungerleider L, Herscovitch P,            Post RM: Brain Regions            Involved in Recognizing Facial Emotion or Identity: An O15 PET study. J Neuropsychiatry and Clinical   Neuroscience 1993, 5;4:384-394.

 

27.       Post RM, Ketter TA, Pazzaglia PJ, George MS, Marangell LB, Denicoff K: New Developments in the Use        of Anticonvulsants as Mood Stabilizers.Neuropsychobiology, 1993, 27:132-137.

 

28.           George MS, Ketter TA, Post RM: SPECT and PET Imaging in Mood Disorders. J Clin Psych 1993,      54[11,suppl]:6-13.

 

29.       George MS, Trimble MR, Robertson MM: Fluvoxamine and Sulpiride in Comorbid Obsessive-Compulsive Disorder and Gilles de la Tourette Syndrome. Human Psychopharmacology: Clinical and Experimental 1993, 8:327-334.

 

30.       Pazzaglia PJ, Post RM, Ketter TA, George MS, Marangell LB: Preliminary controlled trial of nimodipine           in ultra-rapid cycling affective dysregulation. Psychiatry Research  1993, 49:257-272.

 

1994  

 

31.       George MS: Reanimating the Face: Early Writings by Duchenne and Darwin on the Neurology of Facial         Emotion Expression. J Hist Neurosciences 1994, 2:21-33.

 

32.       George MS, Rosenstein D, Rubinow DR, Kling MA, Post RM: CSF magnesium in affective illness: lack           of correlation with clinical course or treatment. Psychiatry Research 1994, 51: 139-146.

 

33.       George MS, Kellner CH, Bernstein H, Goust JM: A Magnetic Resonance         Imaging Investigation into        Mood Disorders in Multiple Sclerosis: A Pilot Study. The Journal of Nervous and Mental Disease 1994, 182,       7: 410-412.        

 

34.       George MS, Guidotti A, Rubinow D, Pan B, Mikalauskas K, Post RM: CSF Neuroactive Steroids in     Affective Disorders: pregnenolone, progesterone and DBI. Biological Psychiatry 1994, 35: 775-780.

 

35.       George MS, Ketter TA, Parekh PI, Rosinsky N, Ring H, Casey BJ, Trimble MR, Horwitz B, Herscovitch P, Post RM: Regional Brain Activity When Selecting a Response Despite Interference: An H215O PET study of the Stroop and an Emotional Stroop. Human Brain Mapping 1994, 1:194-209.

 

36.       George MS, Ketter TA, Parekh P, Gill DS, Huggins T, Marangell L, Pazzaglia PJ, Post RM: Spatial        Ability in Affective Illness:             Differences in Regional Brain Activation During a Spatial Matching Task        (H215O PET). Neuropsychiatry, Neuropsychology and Behavioral Neurology 1994, 7: 143-153.

 

37.       Marangell L, George MS, Bissette G, Pazzaglia PJ, Huggins T, Post RM: Increased CSF thyrotropin-releasing hormone in affective disorder patients treated with carbamazepine. Arch Gen Psych              1994, 51: 625-628.

 

38.       George MS, Lydiard RB: Social Phobia Secondary to Physical Disability: A review of benign essential            tremor and stuttering. Psychosomatics 1994, 35:520-523.

 

39.       George MS, Ketter TA, Post RM: Prefrontal Cortex Dysfunction in Clinical Depression. Depression 1994,       2:59-72.

 

40.       George MS, Wassermann E: Rapid-rate Transcranial Magnetic Stimulation (rTMS) and ECT (editorial).           Convulsive Therapy 1994, 10(4): 251-253.

 

41.       George MS: An Introduction to the Emerging Neuroanatomy of Depression. Psychiatric Annals 1994,            24,12: 635-636.

 

42.       Ketter TA, George MS, Ring HA, Pazzaglia PJ, Marangell L, Kimbrell TA, Post RM: Primary Mood     Disorders: Structural and Resting Functional      Studies. Psychiatric Annals 1994, 24, 12: 637-642.

 

43.       George MS, Ketter TA, Post RM: Activation Studies in Mood Disorders.        Psychiatric Annals 1994, 24,12:    648-652.

 

44.       George MS, Robertson MM, Costa DC, Ell PJ, Trimble MR, Pilowsky L, Verhoeff NPLG: Dopamine     Receptor Availability in Tourette's Syndrome. Psych Res - Neuroimaging 1994,55:193-203.

 

1995

 

45.       George MS, Ketter TA, Parekh PI, Horwitz B, Herscovitch P, Post RM: Regional Brain Activity During            Transient Self-induced Sadness or Happiness in Healthy Women.  American Journal of Psychiatry 1995,152:             341-351.

 

46.       Parekh P, Spencer J, George MS, Gill D, Ketter TA, Horwitz, B, Andreason P, Herscovitch P, Post RM:            Procaine-Induced Increases in Limbic rCBF Correlate Positively with Increases in Occipital and Temporal          EEG Fast Activity. Brain Topography 1995,7:209-216.

 

47.       George MS, Malloy L, Slate SO, Uhde TW: A Pilot MRI Study of Brain Size in Nervous Pointer Dogs.             Anxiety, 1995, 1: 129-133.

 

48.       George MS, Wassermann EM, Williams WA, Callahan A, Ketter TA, Basser P, Hallett M, Post RM:   Daily Repetitive Transcranial Magnetic Stimulation (rTMS) Improves Mood in Depression. NeuroReport   1995, 6, 14:1853-1856.

 

49.       Pazzaglia PJ, George MS, Post RM, Rubinow DR, Davis C: Nimodipine Increases CSF Somatostatin in             Affectively Ill Patients. Neuropsychopharmacology 1995; 13: 75-83. 

 

50.       Ketter TA, Jenkins JB, Schroeder DH, Pazzaglia PJ, Marangell LB, George MS, Callahan AM, Hinton               ML, Chao J, Post RM: Carbamazepine But Not Valproate Induces Buproprion Metabolism. J Clin      Psychopharm 1995, 15: 327-333.

 

51.       George MS: Emotion and the Brain. Clinical Advances in the Treatment of Psychiatric Disorders 1995;            9,6:14-16.*

 

52.       Ketter TA, Flockhart DA, Post RM, Denicoff K, Pazzaglia PJ, Marangell LB, George MS, Callahan AM:           The Emerging Role of Cytochrome P450 3A in Psychopharmacology. J Clin Psychopharmacology   1995;15,6:387-398.

 

53.       George MS: The Clinical Use of SPECT in Depressive Disorders. Journal of Clinical Psychiatry 1995; 56:         542-544.

           

54.       Schuckit MA, Jobst KA, George MS, VanHeertum RL: Difficult Differential Diagnoses in Psychiatry -             The Clinical Use of SPECT. Journal of Clinical Psychiatry 1995; 56:539.

 

1996

55.   Post RM, Weiss SR, Leverich GS, George MS, Frye M, Ketter TA: Developmental Psychobiology of

           Cyclic Affective Illness: Implication for Early Therapeutic Intervention. In, Chichetti D. and Tucker D. (eds)

           Development and Psychopathology.1996; 8:273-305. 

 

56.       George MS, Wassermann EM, Williams W, Steppel J, Pascual-Leone A, Basser P, Hallett M, Post RM:           Changes in Mood and Hormone Levels After Rapid- Rate Transcranial Magnetic Stimulation (rTMS) of the              Prefrontal Cortex. J Neuropsychiatry and Clinical Neuroscience 1996; 8:172-180.

 

57.       George MS, Parekh PI, Rosinsky N, Ketter TA, Kimbrell TA, Heilman K, Herscovitch P, Post RM:       Understanding Emotional Prosody Activates Right Hemisphere Regions. Archives of Neurology 1996;              53:665-670.

 

58.       Ketter TA, Andreason PJ, George MS, Herscovitch P, Post RM: Anterior Paralimbic Mediation of      Procaine-induced Emotional and Psychosensory Experiences. Archives of General Psychiatry 1996;53:59-

           69.

 

59.       Ketter TA, George MS, Kimbrell TA, Benson BE, Post RM: Functional Brain Imaging, Limbic               Function, and Affective Disorders. The Neuroscientist 1996; 2,1:55-65.

 

60.       Poltorak M, Wright R, Hemperly JJ, Frye M, George MS, Pazzaglia PJ, Jerrels S, Post RM, Freed WJ: Increased Neural Cell Adhesion Molecule in              the CSF of Patients with Mood Disorder. J Neurochemistry      1996; 66:1532-1538.

 

61.       George MS, Ketter TA, Parekh PI, Herscovitch P, Post RM: Gender Differences in rCBF During Transient      Self-induced Sadness or Happiness. Biological Psychiatry 1996;40:859-871.

 

62.       George MS, Wassermann EM, Post RM: Repetitive Transcranial Magnetic Stimulation (rTMS): A      Neuropsychiatric Tool for the Twenty-First Century. J Neuropsychiatry Clin Neurosci 1996;8:373-382.

 

63.       Samii A, Wassermann EM, Ikoma K, Mercuri B, George MS, O'Falon A, Dale JK, Straus SE, Hallett     M: Decreased Post-Exercise Facilitation of Motor Evoked Potentials in Patients with Chronic Fatigue        syndrome or Depression. Neurology 1996; 47:1410-1414.

 

64.       Post RM, Ketter TA, Pazzaglia PJ, Denicoff K, George MS, Callahan A, Leverich G, Frye M: Rational polypharmacy in the bipolar affective disorders. Epilepsy Research - Supplement. 1996; 11:153-80.

 

1997

 

65.       George MS, Post RM, Ketter TA, Kimbrell TA, Speer AM: Neural Mechanisms of Mood Disorders.   Current Review of Mood and Anxiety Disorders. 1997; 1:71- 83.

 

66.       Ketter TA, George MS, Kimbrell TA, Brenson BA, Post RM. Functional Brain Imaging in Mood and Anxiety Disorders.Current Review of Mood and Anxiety Disorders. 1997; 1:96-112.

 

67.       George MS: TMS: An Issue Worthy of a Single Focus. CNS Spectrums. 1997;2, 1:17-18.

 

68.       George MS, Speer AM, Wassermann EM, Kimbrell TA, Williams WA, Kellner CH, Risch SC, Stallings            L, Post RM: Repetitive TMS as a Probe of Mood in    Health and Disease. CNS Spectrums.1997;2,1:39-44.

 

69.        Martin JD, George MS, Greenberg BD, Wassermann EM, Schlaepfer TE, Murphy DL, Hallett M, Post

         RM: Mood Effects of Prefrontal Repetitive High-Frequency TMS in Healthy Volunteers. CNS        

         Spectrums.1997;2,1:53-54.

 

70.       George MS, Ketter TA, Parekh PI, Rosinsky N, Ring HA, Pazzaglia PJ, Marangell L, Post RM: Blunted            Left Cingulate Activation in Mood Disorder Subjects During a Response Interference Task (The Stroop). J

            Neuropsychiatry Clin Neurosci. 1997; 9:55-63.

 

71.       Marangell LB, Ketter TA, George MS, Pazzaglia PJ, Callahan AM, Parekh P, Andreason PJ, Horwitz B,            Herscovitch P, Post RM. Thyrotropin-Stimulating Hormone Inversely Correlates With Brain Activity in   Mood Disorders. American Journal of Psychiatry. 1997; 154,2:224-230.

 

72.           Callahan AM, Frye MA, Marangell LB, George MS, Ketter TA, L'Herrou T, Post RM. Comparative Antidepressant Effects of Intravenous and Intrathecal Thyrotropin-Releasing Hormone: Confounding Effects of Tolerance and Implications for Therapeutics. Biological Psychiatry 1997; 41:264-272. 

 

73.       Post RM, Weis SRB, Ketter TA, Denicoff KD, George MS, Frye MA, Smith MA, Leverich GS. The      Kindling Model: Implications for the Etiology and Treatment of Mood Disorders. Current Review of Mood              and Anxiety Disorders 1997; 113-126.

 

74.     Marangell LB, George MS, Callahan AM, Ketter TA, Pazzaglia PJ, L'Herrou TA, Leverich GS, Post RM

         Effects of Intrathecal Thyroptropin-Releasing Hormone (Protirelin) in Refractory Depressed Patients.

         Archives of General Psychiatry. 1997; 54:214-222.

 

75.       George MS, Vincent DJ, Roberts DR, Bohning DE, Patel S, Vera C, Cure J, Horton J, Young J:               Presurgical Mapping of Regional Brain Activity using Echoplanar BOLD fMRI. Advances in Clinical               Research 1997 (Picker White    Papers)*.

 

76.       Greenberg BD, George MS, Dearing J, Benjamin J, Schlaepfer T, Altemus M, Wassermann EM, Hallett            M, Murphy DL. Effect of Prefrontal Repetitive Transcranial Magnetic Stimulation (rTMS) in Obsessive        Compulsive Disorder: A preliminary study. American Journal of Psychiatry 1997;     154:867-869.

 

77.       Bohning DE, Pecheny AP, Epstein CM, Speer AM, Vincent DJ, Dannals W, George MS: Mapping     transcranial magnetic stimulation (TMS) fields in vivo with MRI. Neuroreport 1997; 8: 2535-2538.

 

78.       Fox P, Ingham R, George MS, Mayberg H, Ingham J, Roby J, Martin C, Jerabek P: Imaging Human      Intra-Cerebral Connectivity by PET During TMS. NeuroReport 1997; 8: 2787-2791.

 

79.       George MS, Ketter TA, Parekh P, Gill DS, Marangell L, Pazzaglia PJ, Herscovitch P, Post RM:               Depressed Subjects Have Abnormal Right Hemisphere Activation During Facial Emotion Recognition. CNS      Spectrums 1997; 2,10:45-55.

 

80.       George MS, Wassermann EM, Williams WE, Kimbrell TA, Little JT, Hallett M, Post RM: Mood           Improvements Following Daily Left Prefrontal Repetitive Transcranial Magnetic Stimulation in Patients             with Depression: A placebo-controlled crossover trial. American Journal of Psychiatry 1997; 154:1752-1756.

 

81.       Post RM, Kimbrell TA, McCann U, Dunn RT, George MS, Weiss SR: [Are convulsions necessary for the antidepressant effect of electroconvulsive therapy: outcome of repeated transcranial magnetic stimulation]. [French] Encephale. 23 Sep N03:27-35. 1997 June.    

 

82.       Roberts DR, Vincent DJ, Speer A, Bohning DE, Cure J, Young J, George MS: Multi-modality Mapping            of Motor Cortex: Comparing Echoplanar BOLD fMRI and Transcranial Magnetic Stimulation. J Neural              Transmission. 1997; 104 (8-9): 833-843.

 

83.       Worthington C, Vincent DJ, Bryant AE, Roberts DR, Vera CL, Ross DA, George MS: Comparison of Functional Magnetic Resonance Imaging for Language Localization an Intracarotid Speech Amytal Testing in Presurgical Evaluation for Intractable Epilepsy: Preliminary Results. Stereotactic and Functional Neurosurgery 1997; 69:197-201.

 

84.       Post RM, Kimbrell TA, Frye M, George MS, Mccann U, Little J, Dunn R, Li H, Weiss SRB:      Implications of Kindling and Quenching for the Possible Frequency Dependence of rTMS. CNS    Spectrums.1997;2,1:55-60.

 

Articles, 1998:

 

85.       Bohning DE, Lorberbaum JP, Shastri A, Nahas Z, George MS: Structural Brain Imaging (CT and MRI) in Primary Psychiatry. 1998; 5(3): 46- 51.

 

86.       Nahas Z, George MS, Lorberbaum JP, Risch SC: SPECT and PET in Neuropsychiatry. Primary              Psychiatry. 1998; 5(3): 52 - 59.

 

87.       Lorberbaum JP, Bohning DE, Shastri A, George MS: Functional Magnetic Resonance Imaging (fMRI) for the Psychiatrist. Primary Psychiatry. 1998; 5(3): 60 - 71.

 

88.           George MS, Speer AM, Molloy M, Nahas Z, Teneback CC, Risch SC, Arana GW, Ballenger JC, Post RM: Low frequency daily left prefrontal rTMS improves mood in bipolar depression: a placebo-controlled case report. Human Psychopharmacology: Clinical and Experimental. 1998; 13:271- 275.

 

89.       George MS, Huggins T, McDermut W, Parekh PI, Rubinow D, Post RM: Abnormal Facial Emotion      Recognition in Depression: Serial testing in an ultra-rapid-cycling patient. Behavior Modification. 1998;   22,2: 192-204.

 

90.       George MS: Why Would You Ever Want To?: Toward Understanding the Antidepressant Effect of rTMS.    (Editorial) Human Psychopharmacology: Clinical and Experimental 1998; 13: 307-313.

 

91.       Pridmore S, Filho JAF, Nahas Z, Liberatos C, George MS: Motor Threshold in Transcranial Magnetic              Stimulation: a comparison of a neurophysiological and a visualization of movement method. The Journal of             ECT 1998; 14: 25-27.

 

92.       Bohning DE, Shastri A, Nahas Z, Lorberbaum JP, Andersen SW, Dannels W., Vincent DJ, George MS: Echoplanar BOLD fMRI of Brain Activation Induced by Concurrent Transcranial Magnetic Stimulation (TMS). Investigative Radiology 1998; 33(6):336-340.

 

93.       Wassermann EM, Wedegaertner FR, Ziemann U, George MS, Chen R: Crossed Reduction of Motor Cortex Excitability by 1 Hz Transcranial Magnetic Stimulation. Neurosci Lett 1998; 250(3):141-144.

 

94.          George MS: Advances in Brain Imaging; An Overview of What the Primary Psychiatrist Needs to Know. Primary Psychiatry  1998; 5(3): 37-45.

 

95.       Pazzaglia PJ,  Post RM,  Ketter TA,  Callahan AM,  Marangell LB,  Frye MA,  George MS,  Kimbrell    TA,  Leverich GS,  Coralocatelli G, Luckenbaugh D: Nimodipine monotherapy and Carbamazepine           Augmentation in Patients with Refractory recurrent Affective Illness.  Journal of Clinical   Psychopharmacology 1998; 18(5):404-413.

 

Articles 1999:

 

96.       George MS, Teneback C, Bloomer CW, Horner M, Anton RF: Using Neuroimaging to Understand Alcohol’s Brain Effects. CNS Spectrums: The International Journal of Neuropsychiatric Medicine 1999; 4(1): 88-92.

 

97.       Hamner MB, Lorberbaum JP, George MS: The Potential Role of the Anterior Cingulate Cortex in PTSD: Review and Hypothesis. Depression and Anxiety 1999; 9: 1-14.

 

98.       Nahas Z, Bohning DE, Molloy M, Oustz JA, Risch SC, George MS: Safety and Feasibility of Repetitive Transcranial Magnetic Stimulation in the Treatment of Anxious Depression in Pregnancy. J Clin Psychiatry 1999; 60:50-52.

 

99.       Bohning DE, Shastri A, Blumenthal KM, Nahas Z, Lorberbaum J, Roberts D, Teneback C, Vincent DJ, George MS. A Combined TMS/fMRI Study of Intensity-Dependent TMS over Motor Cortex. Biological Psychiatry 1999; 45: 385-394.

 

100.     Hamner MB, Ulmer HC, Horne DN, George MS, Arana GW: Procaine Administration and Decreased Behavioral Responsivitiy in PTSD: A Pilot Study. Human Psychopharmacology: Clinical and Experimental 1999; 14: 105-111.

 

101.     George MS,  Lisanby SH, Sackeim HA,: Transcranial Magnetic Stimulation: Applications in Neuropsychiatry (Invited News and Reviews). Archives Of General Psychiatry 1999; 56:300-311.

 

102.     George MS, Stallings LE, Speer AM, Spicer KM, Cheng KT, Molloy M, Risch SC, Vincent DJ, Bohning DE: Prefrontal rTMS Reduces Relative Perfusion Locally and Trans-Synaptically.  Human Psychopharmacology: Clinical and Experimental 1999; 14:161-170.

 

103.     George MS, Teneback CC, Malcolm RJ, Moore J, Stallings LE, Spicer KM, Anton RF, Ballenger JC: Multiple Previous Alcohol Detoxifications Are Associated with Decreased Amygdala and Paralimbic Function in the Post-Withdrawal Period.  Alcoholism: Clinical and Experimental Research 1999; 23, 6: 1077-1084.

 

104.     George MS, Nahas Z, Lomarev M, Bohning DE, Kellner CH: How knowledge of regional brain dysfunction in depression will enable new somatic treatments in the next millenium. CNS Spectrums: The International Journal of Neuropsychiatric Medicine 1999; 4, 7: 53-61.

 

105.     Adinoff B, Devous MD, Best S, George MS, Alexander D, Payne K: SPECT following Intravenous Procaine in Cocaine Addiction. Annals of the New York Academy of Science 1999: 807-810.

 

106.        Frye MA, Gary KA, Marangell LB, George MS, Callahan AM, Little JT, Huggins T, Cora-Locatelli G, Osuch EA, Winokur A, Post RM: CSF TRH Gender Differences: Implications for Neurobiology and Treatment of Depression. J Neuropsychiatry and Clinical Neuroscience 1999; 11: 349-353.

 

107.     Kimbrell TA, George MS, Parekh PI, Ketter TA, Podell DM, Danielson AL, Repella JD, Benson BE, Willis MW, Herscovitch P, Post RM: Regional Brain Activity During Transient Self-Induced Anxiety and Anger in Healthy Adults. Biological Psychiatry 1999; 46:454-465.

 

108.     Shastri A, George MS, Bohning DE: Performance of a System for Interleaving Transcranial Magnetic Stimulation with Steady State Magnetic Resonance Imaging.Transcranial Magnetic Stimulation (supplement)to Electroencephalography and Clinical               Electrophysiology. Editors: W. Paulus, M. Hallett, P.M. Rossini, J.C. Rothwell. 1999, 55-64.

 

109.     George MS, Avery D, Nahas Z, Molloy M, Oliver NC, Risch SC, Arana GW: rTMS Studies of Mood and        Emotion. Transcranial Magnetic Stimulation (supplement)to Electroencephalography and Clinical    Electrophysiology. Editors: W. Paulus, M. Hallett, P.M. Rossini, J.C. Rothwell. 1999, 304-314.

 

110.     Teneback CC, Nahas Z, Speer AM, Molloy M, Stallings LE, Spicer KM, Risch SC, George MS:            Two Weeks of Daily Left Prefrontal rTMS Changes Prefrontal Cortex and Paralimbic Activity in Depression. J Neuropsychiatry and Clinical Neurosciences 1999; 11: 426-435.

 

111.     Ketter TA, Kimbrell TA, George MS, Willis MW, Benson BE, Danielson A, Frye MA, Herscovitch P, Post RM: Baseline Cerebral Hypermetabolism Associated with Carbamazepine Response, and Hypometabolism with Nimodipine Response in Mood Disorders. Biological Psychiatry 1999; 46:1364-1374.

 

112.     George MS, Nahas Z, Kozel FA, Goldman J, Molloy M, Oliver NC: Improvement of Depression Following Transcranial Magnetic Stimulation. Current Psychiatry Reports 1999, 1: 114-124.

 

113.     Lorberbaum JP, Newman JD, Dubno JR, Horwitz AR, Nahas Z, Teneback CC, Bloomer CW, Bohning DE,        Vincent D, Johnson MR, Emmanuel N, Brawman-Mintzer O, Book SW, Lydiard RB, Ballenger JC, George               MS: Feasibility of Using fMRI to Study Mothers Responding to Infant Cries. Depression and Anxiety 1999; 3:99-104.

 

114.     Kimbrell TA, Little JT, Dunn RT, Frye MA, Greenberg BD, Wassermann EM, Repella JD, Danielson AL, Willis MW, Benson BE, Speer AM, Osuch E, George MS, Post RM: Frequency Dependence of Antidepressant Response to Left Prefrontal Repetitive Transcranial Magnetic Stimulation (rTMS) as a Function of Baseline Cerebral Glucose Metabolism. Biological Psychiatry 1999; 46:1603-1613.

 

115.     Nahas Z, Molloy M, Hughes PL, Oliver N, Arana GW, Risch SC, George MS: Repetitive Transcranial              Magnetic Stimulation: Perspectives for Application in the Treatment of Bipolar and Unipolar Disorders.       Bipolar Disorders: An International Journal of Psychiatry and Neurosciences.  1999; 2: 73-80.

 

Articles,  2000:

 

116.     George MS, Sackeim HA, Rush AJ, Marangell LB, Nahas Z, Husain MM, Lissanby SH, Burt T, Goldman J , Ballenger JC. Vagus Nerve Stimulation: A new tool for brain research and therapy. Biological Psychiatry 2000; 47:287-295.

 

117.     Rush AJ, George MS, Sackim HA, Marangell LB, Husain M, Giller C, Nahas Z, Haines S, Simson RK, Goodman R, Burt T. Vagus Nerve Stimulation (VNS) for Treatment-Resistant Depressions: A Multicenter Study. Biological Psychiatry 2000; 47:276-286. 

 

118.     George MS: New Methods of Brain Stimulation (ECT, MST, TMS, VNS and DBS) Are Improving OCD           Research and Therapy (From the 4th IOCDC Plenary Lecture). CNS Spectrums 2000; 5,6: 12-17.

 

119.     Kozel FA, Nahasz, deBrux C, Molloy M, Lorberbaum JP, Bohning DE, Risch SC, George MS: How Coil-Cortex Distance Relates to Age, Motor Threshold and Antidepressant Response to Repetitive

            Transcranial Magnetic Stimulation.  J Neuropsychiatry and Clin Neurosciences. 2000; 12,3: 376-384.

 

120.     Little JT, Kimbrell TA, Wassermann EM, Grafman J, Figueras S, Dunn RT, Danielson A, Rupella J, Huggins T, George MS, Post RM. Cognitive Effects of 1 and 20 Hz Repetitive Transcranial Magnetic Stimulation in Depression:Preliminary Report. Neuropsychiatry,Neuropsychology and Behavioral Neurology. 2000; 13(2):119-24.

 

121.     Bohning DE, Shastri A, Wassermann EM, Ziemann U, Lorberbaum JP, Nahas Z, Lomarev MP, George            MS: BOLD-fMRI Response to Single-Pulse Transcranial Magnetic Stimulation (TMS). Journal Of Magnetic     Resonance Imaging 2000; 11: 569-574.

 

122.     Goldman J, Nahas Z, George MS: What is Transcranial Magnetic Stimulation? Harvard Mental Health Letter 2000; 17: 8.

 

123.     George MS, Nahas Z, Speer AM, Molloy M, Oliver NC, Li X, Arana GW, Risch SC, Ballenger JC: A Controlled Trial of Daily Left Prefrontal Cortex TMS for Treating Depression (Priority Communication). Biological Psychiatry 2000; 48 (10): 962-970.

 

124.     Osuch EA, Ketter TA, Kimbrell TA, George MS, Benson BE, Willis MW, Herscovitch P, Post RM:     Regional Cerebral Metabolism Associated with Anxiety Symptoms in Affective Disorder Patients.Biological             Psychiatry 2000; 48 (10): 1020-1023.

 

125.     Bohning DE, Shastri A,  McGavin L, McConnell KA, Nahas Z, Lorberbaum J, Roberts DR, Bloomer C,             Vincent DJ, George MS: Motor cortex brain activity induced by 1-Hz transcranial magnetic stimulation is              similar in location and level to that for volitional movement. Inv Radiology 2000; 35:676-683.

 

126.     Nahas Z, DeBrux C, Chandler V, Lorberbaum JP, Speer AM, Molloy MA, Liberatos C, Risch SC, George MS: Lack of Significant Changes on Magnetic Resonance Scans Before and After 2 Weeks of Daily Left Prefrontal Repetitive Transcranial Magnetic Stimulation for Depression. J ECT 2000; 16:380-390.

 

127.     Nobler MS, Teneback CC, Nahas Z, Bohning DE, Shastri A, Kozel A, George MS: Structural and Functional Neuroimaging of ECT and TMS. Depression and Anxiety 2000; 12: 144-156.

 

128.       George MS, Nahas Z, Bohning DE, Lomarev M, Denslow S, Osenbach R, Ballenger JC: Vagus Nerve Stimulation (VNS): A New Form of Therapeutic Brain Stimulation. CNS Spectrums 2000; 5 :43-52.

 

129.       George MS, Sackheim H, Marangell L, Husain M, Nahas Z, Lisanby S, Ballenger JC, Rush A: Vagus Nerve Stimulation A Potential Therapy for Resistant Depression? The Psychiatric Clinics of North America 2000; 4: 757-783.

 

Articles,  2001:

 

130.     Bohning DE, George MS, Epstein CM: Deconvolution of transcranial magnetic stimulation (TMS) maps. J. Neural Transmission 2001; 108: 35-52.

 

131.     Ketter TA, Kimbrell TA, George MS, Dunn RT, Speer AM, Benson BE, Willis MW, Danielson AL, Frye MA, Herscovitch P, Post RM: Effects of Mood and Subtype on Cerebral Glucose Metabolism in Treatment-Resistant Bipolar Disorders. Biological Psychiatry 2001; 49: 97-109.

 

132.       Adinoff B, Devous MD, Best SM, George MS, Alexander D, Payne JK. Limbic Responsiveness to Procaine in Cocaine Addicted Subjects. American Journal of Psychiatry 2001; 158: 390-398.

 

133.     McConnell KA, Nahas Z, Kozel FA, Lorberbaum JP, Shastri A, Bohning DE, George MS: The TMS Motor Threshold Depends on the Distance from Coil to Underlying Cortex: A Replication in Healthy Adults. Biological Psychiatry 2001; 49: 454-459.

 

134.     Sackeim HA, Keilp JG, Rush AJ, George MS, Marangell LB, Dormer JS, Burt T, Lisanby SH, Husain M, Collum M, Oliver NC, Zboyan H: The Effects of Vagus Nerve Stimulation on Cognitive Performance in Patients with Treatment-Resistant Depression. Neuropsychiatry, Neuropsychology and Behavioral Neurology 2001; 14:53-62.

 

135.     George MS, Anton RF,  Bloomer C, Teneback C, Drobes D, Lorberbaum JP, Nahas Z,Vincent DJ:         Activation of Prefrontal Cortex and Anterior Thalamus in Alcoholic Subjects on Exposure to Alcohol-Specific Cues. Arch Gen Psych 2001; 58:345-352. 

 

136.        Chae JH, Nahas Z, Li XB, George MS: Transcranial Magnetic Stimulation in Psychiatry: Research and

          Therapeutic Applications. International Review of Psychiatry 2001; 13:18-23.

 

137.        Risch SC, McGurkin S, Horner MD, Nahas Z, Owens SD, Molloy M, Gilliard C, Christie S, Markowitz JS, DeVane CL, Mintzer J, George MS: A Double-blind Placebo-controlled Case Study of the Use of Donepezil to Improve Cognition in a Schizoaffective Disorder patient: Functional MRI Correlates. Neurocase 2001; 7: 105-110.

 

138.     Shastri A, Lomarev MP, Nelson S, George MS, Holzworth MR, Bohning DE: A Low-cost System for Monitoring Skin Conductance During Functional MRI. Journal of Magnetic Resonance Imaging. 2001(14): 187-193.

 

139.     George MS: Summary and Future Directions of Therapeutic Brain Stimulation:Neurostimulation and Neuropsychiatric Disorders. In a supplement to Epilepsy and Behavior entitled, Neurostimulation and Neuropsychiatric Disorders (Schachter, Schmidt, George, eds). 2001 (2): S95-S100.         .

 

140.        Nahas Z, Li X, Chae J-H, Oliver NC, Anderson B, Kapp B, George MS: TMS in Depression. In a supplement to Epilepsy and Behavior entitled, Neurostimulation and Neuropsychiatric Disorders (Schachter, Schmidt, George, eds). 2001 (2): S21-S29.

 

141.        Marangell LB, Rush AJ, George MS, Georges D, Sackeim HA: A Review of Vagus Nerve Stimulation for Treatment-Resistant Depression. In a supplement to Epilepsy and Behavior entitled, Neurostimulation and Neuropsychiatric Disorders (Schachter, Schmidt, George, eds). 2001 (2): S6-S10.

 

142.        Bohning DE, Lomarev MP, Denslow S, Nahas Z, Shastri A,  George MS: Vagus Nerve Stimulation (VNS) Synchronized BOLD-fMRI. Investigative Radiology 2001;36: 470-479.

 

143.        Mann K, Agartz I,  Harper C, Shoaf S, Rawlings RR, Momenan R, Hommer DW,  Pfefferbaum A,  Sullivan EV, Anton RF, Drobes DJ, George MS, Bares R, Machulla HJ, Mundle G, Reimold M,  Heinz A: Neuroimaging in alcoholism: Ethanol and brain damage. Alcoholism: Clinical & Experimental Research. 2001. 25(5 Suppl 1):104S-109S

 

144.        Sackeim HA, Rush AJ, George MS, Marangell LB, Husain MM, Nahas Z, Johndon CR, Seifman S, Giller C, Haines S, Simpson RK, Goodman RR: Vagus Nerve Stimulation (VNS) for Treatment-Resistant Depression: Efficacy, Side Effects and Predictors of Outcome. Neuropsychopharmacology. 2001 (25);5:713-728.

 

145.        Nahas Z, Lomarev M, Roberts DR, Shastri A, Lorberbaum JP, Teneback C, McConnell K, Vincent DJ, Li

         X,George MS, Bohning DE: Unilateral Left Prefrontal TMS produces Intensity-Dependent Bilateral Effects   

         as Measured by Interleaved BOLD fMRI. Biological Psychiatry 2001 (50); 9: 712-721.

 

146.     Goodnick PJ, Rush AJ, George MS, Marangell LB, Sackeim HA: Commentary; Vagus Nerve Stimulation in Depression. Expert Opinion in Pharmacotherapy. 2001; 2 (7): 1061-1063.

 

147.     Pridmore S, Khan UA, Reid P, George MS: Transcranial Magnetic Stimulation in Depression: An Overview. German Journal of Psychiatry 2001: 4 (3): 43-50.

 

148.     Nahas Z, Teneback CC, Speer AM, Molloy M, Stallings L, Kozel FA, Spicer KM, George MS: Brain Effects of TMS Delivered Over Prefrontal Cortex in Depressed Adults: Role of Stimulation Frequency and Coil–Cortex Distance J Neuropsychiatry Clin Neurosci 2001 13: 459-470.

 

Articles, 2002:

 

149.     Kimbrell TA, Ketter TA, George MS, Little JT, Benson BE, Willis MW, Herscovitch P, Post RM. Regional Cerebral Glucose Utilization in Patients with a Range of Severities of Unipolar Depression. Biological Psychiatry 2002; 51: 237-252.

 

150.     Marangell LB, Rush AJ, George MS, Sackeim HA, Johnson CR, Husain MM, Nahas Z, Lisanby SH: Vagus Nerve Stimulation (VNS) for Major Depressive Episodes: Longer-term Outcome. Biological Psychiatry  2002; 51:280-287.

 

151.     Lorberbaum JP, Newman JD, Horwitz AR, Dubno JR, Lydiard RB, Brown KJ, Hamner MB, Arana GW, Ballenger JC, George MS: Examining the Brain Regions Involved in Social Attachment: The ThalamoCingulate Gyrus Activates in Mothers Listening to Infant Cries. Biological Psychiatry 2002; 51: 431-445.

 

152.     Willis MW, Ketter TA, Kimbrell TA, George MS, Herscovitch P, Danielson AL, Benson BE, Post RM: Age, sex and laterality effects on cerebral glucose metabolism in healthy adults. Psychiatry Research: Neuroimaging 2002; 114:  23-27.

 

153.     Lomarev M, Denslow S, Nahas Z, Chae J-H, George MS, Bohning DE: Vagus Nerve Stimulation (VNS)

            Synchronized BOLD fMRI Suggests That VNS In Depressed Adults Has Frequency And/Or Dose Dependent Effects At Rest And During A Simple Task. Journal of Psychiatric Research 2002; 36:219-227.

 

154.     George MS: New Methods of Minimally Invasive Brain Modulation as Therapies in Psychiatry: TMS, MST, VNS and DBS. Chinese Medical Journal (Taipei) Chung Hua i Hsueh Tsa Chih 2002; 65:349-360.

 

155.     George MS, Nahas Z, Bohning DE, Kozel FA, Anderson B, Chae J, Lomarev M, Denslow S, Li X, Mu C: Vagus Nerve Stimulation: A Research Update. Neurology (supplement entitled ‘VNS, 5 Years After Approval’) 2002: 59: S56-S61.

 

156.     Kozel FA, George MS: Meta-Analysis of Left Prefrontal Repetitive Transcranial Magnetic Stimulation (rTMS) to Treat Depression. Journal of Psychiatric Practice  2002; 8: 270-275.

 

157.     Kimbrell TA, Dunn RT, George MS, Danielson AL, Willis MW, Repella JD, Benson BE, Herscovitch P, Post RM, Wassermann EM. Left prefrontal-repetitive transcranial magnetic stimulation (rTMS) and regional cerebral glucose metabolism in normal volunteers. Psychiatry Research: Neuroimaging 2002; 115(3): 101-113.

 

158.     George MS: Advances in Brain Stimulation: Guest Editorial. The Journal of ECT 2002; 18 (4):169. 

 

159.     George MS, Nahas Z, Kozel FA, Li X, Denslow S, Yamanakka K, Mishory A, Foust MJ, Bohning DE. Mechanisms and State of the Art of Transcranial Magnetic Stimulation. The Journal of ECT. 2002; 18(4): 170-181.

 

160. George MS, Nahas Z, Li X, Kozel FA, Anderson B, Yamanaka K: Potential New Brain Stimulation Therapies in Bipolar Illness: Transcranial Magnetic Stimulation (TMS) and Vagus Nerve Stimulation (VNS). in a special volume of Clinical Neuroscience Research  (2002; 256-265. (Robert M. Post, ed), entitled Depression in Bipolar Illness: The Stepchild.

 

161.     George MS, Nahas Z, Li X, Kozel FA, Anderson B, Yamanaka K, Chae J-H, Foust MJ: Novel Treatments of Mood Disorders Based on Brain Circuitry (ECT, MST, TMS, VNS, DBS). Seminars in Clinical Neuropsychiatry 2002;7(4):293-294.

 

Articles, 2003:

 

162.        Frye MA, Pazzalia PJ, George MS, Luckenbaugh D, Vanderham E, Davis CL, Rubinow DR, Post RM: Low CSF Somatostatin Associated with Treatment Response to Nimodipine in Patients with Affective Illness. Biological Psychiatry 2003; 53(2):180-183.

 

163.        Nahas Z, Kozel FA, Li X, Anderson B, George MS: Left Prefrontal Transcranial Magnetic Stimulation (TMS) Treatment of Depression in Bipolar Affective Disorder: A pilot study of acute safety and efficacy. Bipolar Disorders 2003; 5 (1):40-47.

 

164.        Pridmore S, Khan U, Rosa MA, George MS: Information for assistants of repeated transcranial magnetic stimulation (TMS). International Journal of Mental Health Nursing 2003;12:22-29.

 

165.        George MS, Rush AJ, Sackeim HA, Marangell L: Vagus Nerve Stimulation (VNS) Utility in Neuropsychiatric Disorders. International Journal of Neuropsychopharmacology 2003; 6: 73-83.

 

166.        McConnell KA, Nahas Z, Shastri A, Teneback C, Lorberbaum JP, Lomarev M, Vincent DJ, Bohning DE, George MS: BOLD fMRI response to direct stimulation (transranial magnetic stimulation) of the motor cortex shows no decline with age. J Neural Transmission 2003; 110:495-507.

 

167.        Bohning DE, Shastri A, Lomarev MP, Loberbaum JP, Nahas Z, George MS: BOLD-fMRI Response versus Transcranial Magnetic Stimulation (TMS) Pulse Train Length: Testing for Linearity. Journal of Magnetic Resonance Imaging 2003; 17(3): 279-290.

 

168.        George MS, Nahas Z, Kozel FA, Li X, Yamanaka K, Mishory A, Bohning DE: Mechanisms and State of the Art of Trancranial Magnetic Stimulation. CNS Spectrums 2003; 8(7): 496-514.

 

169.        Belmaker RH, Fitzgerald P, George MS, Lisanby SH, Pascual-Leone A, Schlaepfer TE, Wassermann EM: Managing the Risks of Repetitive Transcranial Magnetic Stimulation. CNS Spectrums 2003; 8(7): 489.

 

Articles, (In Press):

 

1.             Bohning DE, Denslow S, Bohning PA, Walker JA, George MS: TMS coil positioning/holder system for MR image-guided TMS interleaved with fMRI. Clinical Neurophysiology (In Press, 6/03)

 

2.             Davey K, Epstein CM, George MS, Bohning DE:  Modeling the Effects of Electrical Conductivity of the Head on the Induced  Electrical Field in the Brain During Magnetic Stimulation. Clinical Neurophysiology (In Press 5/03).

 

4.         Roberts DR, Kelley W, Carroll JS, Haines SJ, George MS: Reproducibility of Functional MRI Activation in Clinical Practice. Applied Radiology (In Press, 10/02).

 

5.         Nahas Z, George MS, Molloy M, Gilliard C, Horner MD, Owens SD, McGruk, S, Palecko S, Markowitz JS, DeVane L, Risch SC: Augmenting an Atypical Antipsychotic with a Cognitive Enhancer (Donepezil) Improves Prefrontal Activity in Schizophrenia Patients: A Double-blind Placebo Controlled BOLD fMRI Study. NeuroCase (In Press 10/02).

 

6.         Chae JH, Nahas Z, Lomarev M, Denslow S, Lorberbaum JP, Bohning DE, George MS: A Review of Functional Neuroimaging Studies of Vagus Nerve Stimulation (VNS). Journal of Psychiatric Research (in Press 11/02).

 

7.         Kozel FA, Revell LJ, Lorberbaum JP, Shastri A, Nahas Z, Horner MD, Elhai JD, Bohning DE, George MS: Regional Brain Correlates of Deception: a Pilot fMRI Study in Healthy Young Men. J Neuropsychiatry and Clinical Neurosciences  (In Press 12/02).

 

8.         Kozel FA, George MS, Simpson, KN: Decision Analysis of Cost Effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) versus Electroconvulsive Therapy (ECT) for Treatment of Non-psychotic Severe Depression. CNS Spectrums (In Press, 33/02).

 

9.              George MS: Tickling the brain: The emerging new science of electrical brain stimulation. Scientific American, in an issue on frontiers in neuroscience. (In press 4/03).

 

10.           Li XB, Nahas Z, Lomarev M, Denslow S, Shastri A, Bohning DE, George MS: Prefrontal Cortex TMS Does Not Change Local Diffusion: An MRI Study in Patients With Depression. Cognitive and Behavioral Neurology. (In Press 5/03).

 

11.           Bohning DE, Denslow S, Bohning PA, Lomarev M, George MS: Interleaving TMS with fMRI. EEG and Clinical Neurophysiology (Supplement) (In Press 6/03).

 

12.           Myrick H, Anton R, Li X, Henderson S, Drobes D, Veronin K, George MS: Differential Brain Activity in Alcoholics and Social Drinkers to Alcohol Cues: Relationship to Craving. Neuropsychopharmacology (In Press, 7/03).

 

Articles, (Submitted and Under Review):

 

1.         Chae JH, Nahas Z, Wassermann EM, Li X, Sethuraman G, Gilbert DL, Sallee FR, George MS: A Pilot Study Using rTMS to Probe the Functional Neuroanatomy of Tics in Tourette Syndrome. Neuropsychiatry, Neuropsychology and Behavioral Neurology (Submitted 12/01).

 

2.         Najib A, Lorberbaum JP, Kose S, Bohning DE, George MS: Regional Brain Activity in Women Grieving A Romantic Relationship Breakup. American Journal of Psychiatry (Submitted 9/02).

 

3.         Nahas Z, Li X, Kozel FA, Mirski D, Memoun M, Miller K, Yamanaka K, Anderson B, Chae J, Bohning DE, Mintzer J, George MS: Safety and Possible Beneficial Effects of Distance-Adjusted Prefrontal TMS in Geriatric Depression. Journal of Clinical Psychiatry (submitted 5/02).

 

4.         Lomarev M, Denslow S, George MS, Bohning DE: A Direct Comparison Of The Local And Regional Brain Effects (BOLD fMRI) Of TMS-Induced Compared To Volitional Movement. Neuroimage (submitted 9/02).

 

5.         Conway CR, Chibnall JT, Fletcher JW, Filla-Taylor J, Grossberg GT, Li X, George MS: Vagus Nerve Stimulation Increases Limbic/Paralimbic Activity in Treatment-Resistant Depressed Patients. Biological Psychiatry (Submitted 8/01/02).

 

6.         Chae JH, Nahas Z, Lomarev M, Denslow S, Bohning DE, George MS: Changes in Brain Activity over 10 Weeks of Vagus Nerve Stimulation (VNS) in Patients with Major Depression. Psychiatry Research – Neuroimaging. (Submitted 8/02).

 

7.              Li X, Teneback CC, Nahas Z, Kozel FA, Large C, Cohn J, Bohning DE, George MS: Interleaved TMS/fMRI Demonstrates that Lamotrigine Inhibits Cortical and Enhances Limbic Excitability in Healthy Young Men. Neuropsychopharmacology  (Submitted 8/02).

 

8.              Roberts DR, Kelley W, Carroll J S, Ramsey P, Funke FW, Koola JD, Horner MD, George MS: Motor Cortex BOLD fMRI Activation Correlates with Cortical Excitability Measured by Transcranial Magnetic Stimulation. Radiology (Submitted 7/03).

 

9.              Denslow S, Lomarev M, George MS, Bohning DE: TMS-Induced versus Volitionally-Induced BOLD Response in the Motor Cortex: High Resolution Comparison of Location, Intensity and Repeatability. Cogn and Behavioral Neurology (Submitted 4/03).

 

10.           Bedwell JS, Horner MD, Yamanaka K, Li X, Myrick H, Nahas Z, George MS: Brain Networks Involved with Subcomponent Cognitive Processes of Verbal Working Memory. NeuroImage (Submitted 5/03).

 

11.           Li X, Nahas Z, Anderson B, Kozel FA, George MS: Can rTMS be used as a maintenance treatment for bipolar depression? Depression and Anxiety (Submitted 6/03).

 

12.           Yamanaka K, Nahas Z, Horner MD, Li X, Anderson B, George MS: A Preliminary Study Suggesting that Image-Guidance Improves the Ability of TMS to Interact with Cognitive Circuits. Psychiatry Research (Submitted 10/02).

 

13.           Mu Q, Bohning DE, Nahas Z, Walker J, Anderson B, Denslow S, Lomarev M, Moghadam P, Chae J, George MS: Pulse-Width Dependent Acute Effects of Vagus Nerve Stimulation in Patients with Depression Using fMRI. Biological Psychiatry (Submitted 8/03).

 

 

 

           

 

 

Book Chapters:

 

 1.        George MS, Ashwal S: Jean Martin Charcot. In, The Founders of Child Neurology (S. Ashwal,ed.) (San Francisco: Norman Publishing, 1990) 182-189.

 

 2.        George MS: Neuropathology of Parkinson's Disease. Unit 1 in the monograph, Parkinson's Disease Learning System. (Chapel Hill NC: Health Sciences Consortium, 1989) (Somerset Pharmaceuticals).

 

 3.        Morton WA, George MS: Diagnosis and treatment of Parkinson's Disease. Unit 2 in the monograph, Parkinson's Disease Learning System (Chapel Hill, NC: Health Sciences Consortium, 1989) (Somerset Pharmaceuticals).

 

 4.        Post RM, Weiss SRB, Ketter TA, George MS, Clark M, Rosen J: The temporal lobes and affective disorders. In The Temporal Lobe and Limbic System: Basic and Clinical Perspectives (T. Bolwig, M. Trimble (eds.)) Wrightson Biomedical Publishing Limited, England (1992; 247-265).

 

 5.        Post RM, George MS, Ketter TA, Denicoff K, Leverich G, Mikalauskas K: Mechanisms underlying cycle accelerations in affective disorders: Implications for long-term treatment. In (S. Montgomery, ed.) Psychopharmacology of Depression. Oxford: Oxford University Press (1994) 141-169.

 

 6.        George MS: The Contributions of PET and SPECT Toward a Psychopharmacologic Neuroanatomy of Obsessive-compulsive Disorder. In Human Psychopharmacology: Methods and Measures (Vol 4) I. Hindmarch, P.D. Stonier (Eds.) Chichester: John Wiley and Sons 1993 (pp.99-122).

 

 7.        George MS: Neuroactivation studies using SPECT: The current status.In Braindiagnosis with Radionuclides: Current status and future aspects G.S. Limouris, S.K. Shukla (Eds.) Athens: Mediterra 1992.

 

8.         George MS, Kouris K, Ring HA, Costa DC, Ell PJ: Imaging Human Motor Cortex Activation With HMPAO SPECT. In Braindiagnosis with Radionuclides: Current status and future aspects G.S. Limouris, S.K. Shukla (Eds.) Athens: Mediterra 1992.

 

9.         George MS: New Directions in Obsessive-Compulsive Disorder. In Current Approaches to Psychiatry,           Duphar, 1992.

 

10.       Post RM, Ketter TA, Pazzaglia PJ, Denicoff K, Marangell L, George MS: Anticonvulsants in Refractory          Mood Disorders.In Refractory Depression:  Current Strategies and Future Directions. W.A. Nolan, J. Zohar,

            S.P.Roose and J.D. Asterdam (Eds.) Chichester: John Wiley and Sons, 1994 (pp.97-113).

 

11.       Post RM, Ketter TA, George MS: Psychiatric Syndromes and the Limbic System. American Academy of        Neurology Symposium, 'The Limbic System in Neurology and Psychiatry' April 26, 1993, New York, N.Y.

 

12.       George MS, Ketter TA, Kimbrell TA, Post RM: Brain Imaging. In Mania: Clinical and Research Perspectives. P.J. Goodnick (Ed.) American Psychiatric Press: Washington, DC, 1997, Chapter 11, 191-241.

 

13.       Ketter TA, Post RM, Denicoff K, Pazzaglia PJ, Marangell LB, George MS, Callahan AM: Carbamazepine         in the Treatment of Mania. in Mania: Clinical and Research Perspectives. P.J. Goodnick (Ed.) American     Psychiatric Press: Washington, DC, 1997, Chapter 13, 263-301.

 

14.       George MS, Ketter TA, Post RM: What Functional Imaging Studies Have Revealed About the Brain Basis    of Mood and Emotion. In Advances in  Biological Psychiatry, 2nd Ed. J. Panksepp (Ed.). JAI Press: Greenwich, Conn. 1996 Chapter 3, 63-113.

 

15.       George MS, Greenberg BD: Obsessive-Compulsive Behavior. In Epilepsy: A Comprehensive Textbook. J       Engel, TA Pedly (eds). Raven Press, NY 1997, Volume 3, Chapter 269, 2791- 2796.

 

16.       Post RM, Weiss SRB, Ketter TA, Denicoff KD, George MS, Frye M, Leverich GR. Kindling:   Implications for the Etiology and Treatment of Mood Disorders.In Current Review of Mood Disorders. A.        John Rush (ed.) Current Medicine, Philadelphia, PA (In Press).

 

17.       Ketter TA, George MS, Kimbrell TA, Willis MW, Benson BE, Post RM: Neuroanatomical Models and            Brain Imaging Studies. In Joffe RT, Young LT (eds) Bipolar Disorder: Neurobiology and Clinical        Applications. Marcel Dekker, Inc., New York, 1995 (In Press). 

 

18.       Post RM, Ketter TA, Denicoff K, Pazzaglia PJ,  Marangell LB, Callahan AM, George MS, Frye MA: The Place of anticonvulsant therapy in bipolar illness. In Psychopharmacology (1996) 128:115-129.

 

19.       George MS, Ketter TA, Kimbrell TA, Speer AM, Lorberbaum J, Liberatos CC, Nahas Z, Post RM:       Neuroimaging Approaches to the Study of Emotion. In The Neuropsychology of Emotion (J. Borod Ed.).     Oxford University Press, 1998, (In Press).

 

20.       Ketter TA, Bench CJ, George MS, Kimbrell TA, Post RM: Structural and Functional Brain Imaging in Resistant Mood Disorders. In Textbook of Refractory Mood Disorders. (M. Hornig-Rohan, JD Amsterdam, A  Nierenberg (Eds.)). Cambridge University Press, Cambridge, 1997.

 

21.       George MS, Speer AM, Bohning DE, Risch SC, Vincent DJ, Upadhyaya V, Kellner CH, Arana GW,     Ballenger JC: New Methods for Understanding How the Brain Regulates Mood: Serial Perfusion fMRI and            Transcranial Magnetic Stimulation. In Neuroimaging in Psychiatry, Rauch and Dougherty (eds), APA Press,           1998.

 

22.       George MS, Nahas Z, Speer AM, Kimbrell TA, Wassermann EM, Teneback CC, Molloy M, Bohning DE, Risch SC, Post RM: Transcranial Magnetic Stimulation: A New Method for Investigating the Neuroanatomy of Depression. In New Models of Depression, K. Ebmeier D. Ebert(eds), Karger, Basel; Advances in Biological Psychiatry, 19, 1998 vol 19 pp 94-122. 

 

23.       George MS, Nahas Z, Speer AM, Lorberbaum J, Wassermann EM, Teneback CC, Molloy M, Bohning DE, Risch SC, Post RM: Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Depression: Placebo-Controlled Clinical Trials and Combinations with Neuroimaging. In Magnetic Fields: Recent Advances in Diagnosis and Therapy. Prato (ed).

 

24.       George MS, Nahas Z, Lorberbaum JP, Bohning DE, Shastri A, Speer AM, Wassermann EM, Greenberg BD, Risch SC: Mood and Emotion. In Handbook of Magnetic Stimulation. Pascual-Leone, Davey, Wassermann, Rothwell (eds.), Arnold Publishers, 1998.

 

25.       George MS, McConnell KA, Lorberbaum J, Greenshields A, Bohning DE, Mintzer J: (George et al., 2000)In Textbook of Geriatric Neuropsychiatry (2nd Edition), American Psychiatric Press, Inc. Coffey and Cummings (Eds). 2000. pp. 267-284

 

26.          George MS, Belmaker RH: Historical Overview. In Transcranial Magnetic Stimulation in Neuropsychiatry.  American Psychiatric Press, Inc, (George and Belmaker (Eds). 1999.

 

27.       George MS, Nahas Z, Bohning DE, Shastri A, Teneback C, Roberts DR, Speer AM, Lorberbaum JP,   Vincent DJ, Owens SD, Kozel FA, Molloy M,  Risch SC: Trancranial Magnetic Stimulation and        Neuroimaging. In Transcranial Magnetic Stimulation in Neuropsychiatry.  American Psychiatric Press, Inc,    (George and Belmaker (Eds). 1999.

 

28.       George MS, Sallee FR, Nahas Z, Oliver NC, Wassermann EM: Transcranial Magnetic Stimulation (TMS)        as a Research Tool in Tourette Syndrome and Related Disorders. In Tourette Syndrome and Associated     Disorders. (Advances in Neurology) (Cohen, Goetz, Jankovic (eds)). 2001, pp 225-235.

 

29.       George MS, Lorberbaum JP, (MacLean P): Sexual Function in the Human Brain. In Encyclopedia of the Human Brain. Academic Press, 2002. pp. 355-365.

 

30.       George MS, Bohning DE: Measuring Brain Connectivity with Functional Imaging and Transcranial Magnetic Stimulation (TMS). In, Neuropsychopharmacology, Fifth Generation of Progress. Lipincott, Williams and Wilkins,Chapter 30, pp. 393-410, 2002.

 

31.       George MS: The Challenge of Deconvolving the Obsessive Compulsive Disorder Spectrum into Its Component Diseases. In Obsessive-Compulsive Disorder. Part of the World Psychiatry Association Series - Evidence and Experience in Psychiatry, Vol. 4, John Wiley and Sons, New York, 2000, pp. 244-246.

 

32.       George MS, Sackeim HA, Marangell LB, Husain MM, Nahas Z, Lisanby SH, Ballengjer JC, Rush AJ: Vagus Nerve Stimulation; A Potential Therapy for Resistant Depression. In Psychiatric Clinics of North America; Deoressuib; Recent Develoopments and Innovative Treatments (A. Nierenberg, ed). Volume 23 (4): Philadelphia, WB Saunders, December 2000, p757-783.

 

33.       George MS, Chae J-H, ,Nahas Z, Li X, Najib A, Lomarev M, Denslow S, Oliver NC, Bohning DE: Transcranial Magnetic Stimulation (rTMS) for the Treatment of Depression: Current Knowledge and Future Directions, in Psychiatric Clinics of North America; Annual of Drug Therapy, Volume 8: Philadelphia, WB Saunders, 2001; pp.31-54.

 

34.       George MS, Nahas Z, Li X, Chae J-H, Oliver NC, Najib A, Anderson B: New Depression Treatment Strategies: What Does the Future Hold for Therapeutic Uses of Minimally Invasive Brain Stimulation? A chapter in the American Psychiatric Press Review of Psychiatry (Volume 20). Within a section on ‘Treatment of Resistant Depression’, John Greden (Ed). 2000, chapter 5, pp. 103-142.

 

35.       Hamner MB, Lorberbaum JP, George MS: Limbic System. In The Corsini Encyclopedia of Psychology     and Behavioral Science, 3rd Edition, volume 2. (Craighead WE, Nemeroff CB, eds). 2001, Wiley, New York: 

                  884-887.

 

36.          Rush AJ, George MS, Sackeim HA, Marangell LB, Husain MM, Nahas Z, Burt T, Johnson C: Vagus Nerve Stimulation, in Psychiatric Clinics of North America; Annual of Drug Therapy, Volume 8: Philadelphia, WB Saunders, 2001; pp.55-87.

 

37.          George MS, Kozel FA. Other Antidepressant Therapies – Light Therapy, ECT, TMS, VNS. in Advances in the Management and Treatment of Depression. Thase and Potokar (Editors), Martin Dunitz Publishing, 2002.

 

38.         George MS, Nahas Z, Bohning DE, Kozel FA, Anderson B, Chae J, Li X, Mu C. Potential Mechanisms of Action of VNS for Depression. In Vagus Nerve Stimulation (2nd Ed), Schachter and Schmidt (Eds), Martin Dunitz Publisher. 2002.

 

 

39.         George MS, Nahas Z, Lisanby SH, Schlaepfer T, Kozel FA, Greenberg BD. Transcranial Magnetic Stimulation. In Neurosurgery Clinics of North America  Volume 14/Number 2 (Rezai, Rasmussen and Greenberg, eds). Harcourt, 2003, 283-301.

 

40.          George MS, Myrick H, Li X, Anton R. Assessing the Brain Sequelae of Alcoholism using Brain Imaging. in Alcoholism: A Practical Handbook, Johnson, Ruiz and Galanter (eds), Lippincott, Williams and Wilkins, 2003.

 

41.          George MS, Nahas Z, Kozel FA, Li X, Yamanaka K, Mishory A, Hill S, Bohning DE: Repetitive Transcranial Magnetic Stimulation (rTMS) for Depression and Other Indications. In Bioelectromagnetic Medicine, P. Rosch, M Markov (eds), Marcel Dekker.

 

42.          George MS, Nahas Z, Kozel FA, Li X, Yamanaka K, Mishory A, Hill S, Bohning DE: Potential Therapeutic Uses of TMS in Psychiatric Disorders. In Magnetic Stimulation in Clinical Neurophysiology, Hallett, Chokroverty (eds), Butterworth-Heineman.

 

43.          Kose S, George MS: Functional Magnetic Resonance Imaging Investigations in Mood Disorders. In: Soares JC, ed, Brain Imaging in Affective Disorders, ed,  New York: Marcel Decker, Inc,  2003: 119-157.

 

44.          George MS: Transcranial magnetic stimulation and vagus nerve stimulation: new approaches to antidepressant treatment. In Den Boer, ter Horst, George (eds), Current and Future Developments in Psychopharmacology. Benecke NI, Amsterdam, The Netherlands.

 

 

 

 

Books:

 

 

 

Written:

 

George MS, Ring HA, Costa DC, Ell PJ, Kouris K, Jarritt P: Neuroactivation and Neuroimaging with SPET.    London: Springer-Verlag, 1991.

 

 

 

Edited:

 

George MS, Belmaker RH (eds.): Transcranial Magnetic Stimulation in Neuropsychiatry.  American Psychiatric         Press, Inc, 2000.       

 

JA den Boer, GJ ter Horst, MS George (eds): Current and Future Developments in Psychopharmacology.

Elsevier Press, Inc. 2003
Selected Abstracts for National and International Presentations:

 

 1.        Hill EG, George MS: The 'therapeutik method of headach' in the Seventeenth Century. Neurology 1987;36:219.

 

 2.        George MS: The Debate About the Etiology of Cerebral Palsy, Sigmund Freud vs. William Little. Who was correct? Neurology 1988;.

   

 3.        George MS, Brewerton TD: A Study of the Seasonal Variation of Migraine. Headache 1989;29,5:232.

 

 4.        George MS, Brewerton TD: Seasonal Variation of Migraine. Biological Psychiatry (30) 1990;27:54A.

 

 5.        George MS, Trimble MR: The Changing 19th Century View of Epilepsy as Reflected in the West Riding Lunatic Asylum Medical Reports, Vols 1-6, 1871-1876. Neurology 1991;41(s):335(#771S).

 

 6.        George MS, Costa DC, Kouris K, Ring H, Ell PJ: 99Tcm-HMPAO SPET Abnormalities in Infantile Autism. Nuclear Medicine Communications (12) 1991; 4:275.

 

 7.        Ring HA, George MS, Costa DC, Kouris K, Ell PJ: First Demonstration of Parietal Lobe Activation with Single Photon Emission Tomography (SPET). Nuclear Medicine Communications (12) 1991; 4:273.

 

 8.        Brewerton TD, George MS: Is Migraine Related to the Eating Disorders? Biological Psychiatry Annual Meeting, May 1991, New Orleans, LA.

 

 9.        Ring HA, George MS, Costa DC, Kouris K, Ell PJ: A Demonstration of Parietal Lobe Activation with SPET. American Psychiatric Association New Research Program and Abstracts 1991; NR 35:57.

 

10.       George MS, Robertson MM, Costa DC, Ell PJ: D2 Receptor Activity in Tourette Syndrome (GTS). American Psychiatric Association 144th Annual Meeting New Research Program and Abstracts 1991; NR33:56.

 

11.       George MS, Costa DC, Kouris K, Ring HA, Trimble MR, Ell PJ: HMPAO SPECT Abnormalities in Infantile Autism. American Psychiatric Association 144th Annual Meeting New Research Program and Abstracts 1991; NR 104:73.

 

12.       George MS, Robertson MM, Costa DC, Trimble MR, Ell PJ: HMPAO SPECT Scans of Co-Morbid OCD/GTS Patients. American Psychiatric Association 144th Annual Meeting New Research Program and Abstracts 1991: NR34:57.

 

13.       George MS, Costa DC, Robertson MM, Trimble MR, Ell PJ: HMPAO SPECT Imaging of Patients with Gilles de la Tourette Syndrome and Obsessive-Compulsive Disorder. Biological Psychiatry 1991; 29:442S-443S.

 

14.       George MS, Trimble MR, Robertson MM: A pharmacologic (5HT vs D2) probe of patients with comorbid OCD and Gilles de la Tourette Syndrome. Biological Psychiatry 1991; 29: 444S.

 

15.       Kellner CH, George MS, Goust, JM, Bernstein H: An MRI Investigation into Mood Disorders in Multiple Sclerosis Patients. Biological Psychiatry 1991;29: 564S.

 

16.       Ring H, George M, Ell P, Costa DC, Trimble M: A Parietal activation task with Single Photon Emission Tomography (SPECT). Biological Psychiatry 1991;29: 270S.

 

17.       Costa DC, George MS, Ell PJ, Verhoeff NPGL, Robertson MM: D2 Dopamine receptor studies in patients with Gilles de la Tourette Syndrome. European Congress of Nuclear Medicine, September 1991, Vienna, Austria.

 

18.       George MS, Costa DC, Robertson MM, Ell PJ: Frontal Lobe abnormalities in Gilles de la Tourette Syndrome Patients (GTS) with Obsessive-Compulsive Disorder. European Congress of Nuclear Medicine, September 1991, Vienna, Austria.  

 

19.       George MS, Jones M, Post RM, Mikaluskas K, Leverich G: The Longitudinal course of affective illness: mathematical models involving chaos theory. Society of Biological Psychiatry Annual Meeting, April 1992, Washington, DC, Abstract #58, Biol Psychiatry 1992;31:86-87A.

 

20.       George MS: Neuroimaging Studies of OCD, part of a symposium on The Neurology of OCD, APA 1992 Annual Meeting, Washington, DC, Abstract # 2D, 1992 CME Syllabus & Proceedings Summary:19.

 

    21.   George MS, Moriarty J, Trimble MR, Robertson MM: Trial of Fluvoxamine and Sulpiride in the Treatment of Co-morbid Obsessive-Compulsive Disorder and Gilles de la Tourette Syndrome. Abstract # P-19, 149. 18th Collegium Internationale Neuro-Psychopharmacologicum Congress, in Clinical Neuropharmacology 1992;15: sB, 313B.

 

    22.   Post RM, Ketter TA, Pazzaglia PJ, George MS, Marangell L, Weiss SRB: Receptor, Ion Channel and Neuropeptide Targets for Drug Development: Implications From the Anticonvulsant Model. American College of Neuropsychopharmacology 1992.

 

    23.   George MS, Post RM, Jones M, Mikalauskas K, Leverich G, Pazzaglia PJ: Chaos-Derived Models of the Course of Affective Illness. American College of Neuropsychopharmacology 1992

 

    24.   George MS: SPECT and PET Imaging in Primary Mood Disorders, part of a symposium on SPECT Imaging in Psychiatry: A New Look at Depression, APA 1993 Annual Meeting, San Francisco, CA.

 

    25.   Post RM, George MS, Pazzaglia PJ, Weiss SRB: Routes to Rapid Cycling: Possible Pathophysiologic Mechanisms, part of a symposium on Rapid Cycling Mood Disorders, APA 1993 Annual Meeting, San Francisco, CA.

 

    26.   George MS: Reanimating the Face: Early writings by Duchenne and Darwin on the neurology of facial emotion expression, 1993 AAN, Neurology 43, A283, 501S, New York, NY.

 

    27.   George MS, Ketter TA, Gill D, Herscovitch P, Post RM: The neuroanatomy of facial emotion recognition. 146th Annual Meeting of the American Psychiatric Association, May 22-27, 1993, San Francisco, CA.

            NR 16, p. 63.

 

    28.   Ketter TA, Andreasen PJ, George MS, Herscovitch P, Post RM: Paralimbic rCBF increases during procaine induced psychosensory and emotional experiences, Biological Psychiatry 1993 Annual Meeting, San Francisco, CA. Biol Psychiatry 1993:33:66A (#107).

 

    29.   George MS, Guidotti A, Rubinow D, Mikalauskas K, Post, RM: CSF Neurosteroids in affective disorders: pregnelone, progesterone and DBI. Biological Psychiatry 1993 Annual Meeting, San Francisco, CA Biol Psychiatry 1993:33:67A (#112).

 

   30.    George MS, Ketter TA, Gill D, Marangell LB, Pazzaglia PJ, Post RM: Blunted CBF with Emotion Recognition in Depression. 146th Annual Meeting of the American Psychiatric Association, May 22-27, 1993, San Francisco, CA. NR 114, p. 88.

 

   31.    Ketter TA, Andreasen PA, George MS, Pazzaglia PJ, Marangell LB, Post RM: Blunted CBF response to procaine in mood disorders. 146th Annual Meeting      of the American Psychiatric Association, May 22-27, 1993, San Francisco, CA.

 

   32.    Ketter TA, Andreasen PA, George MS, Marangell LB, Pazzaglia PJ, Post RM: Reduced resting frontal lobe CBF in mood disorders. 146th Annual Meeting of the American Psychiatric Association, May 22-27, 1993, San Francisco, CA.

 

   33.    Pazzaglia PJ, Post RM, Ketter TA, George MS, Marangell LB: Nimodipine in affective illness. 146th Annual Meeting of the American Psychiatric Association, May 22-27, 1993, San Francisco, CA.

 

   34.    Parekh P, Spencer J, George MS, Gill DS, Ketter TA, Post RM: Human rCBF Correlates of EEG Before and After IV Procaine. #501.9, M-46, p.239 Society for Neuroscience 1993, Washington, DC.

 

   35.    Post RM, Pazzaglia PJ, Ketter TA, George MS, Marangell L: Carbamazepine and Nimodipine in Refractory Bipolar Illness: Efficacy and Mechanisms. 1st International Congress on Hormones, Brain and Neuropsychopharmacology, Sept. 13-17, 1993, Rhodes, Greece.

 

   36.    George MS, Ketter TA, Post RM: Brain imaging in mania. 147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA.

 

   37.    George MS (Chair) symposium entitled, 'The Emerging Neuroanatomy of Depression.'147th Annual Meeting of the American Psychiatric Association,       May 22-26, 1994, Philadelphia, PA.

 

   38.    George MS: Introduction to the Neuroanatomy of Depression. 147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA.

 

   39.    Ketter TA, George MS, Pazzaglia PJ, Marangell LB, Andreasen PJ, Post RM: PET Activation Studies in Mood Disorders. 147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA.

 

   40.    George MS, Ketter TA, Parekh PI, Ring HA, Rosinsky N, Pazzaglia PJ, Marangell L, Post RM: Differences in performance and regional brain activation in controls and mood-disordered subjects while performing a classic and emotional Stroop. American College of Neuropsychopharmacology 1993.

 

   41.    Post RM, Pazzaglia PJ, Ketter TA, Marangell L, George MS: Efficacy of the L-type Calcium Channel Blocker Nimodipine in Recurrent Affective Disorders. American College of Neuropsychopharmacology 1993.

 

42.           George MS, Ketter TA, Post RM: An Overview of Brain Activation Studies in Mood Disorders. Biological Psychiatry 1994, Philadelphia, PA.

 

   43.    George MS, Ketter TA, Parekh PI, Post RM: Regional Blood Flow Correlates of Transient Self-induced Sadness or Happiness. Biological Psychiatry 1994, Philadelphia, PA.

 

   44.    Kelly A, Moriarty J, George MS: Fluvoxamine vs Clomipramine in OCD: a multi-center, randomized, double-blind study. XIX CINP Congress, Washington, D.C. 1994, Neuropsychopharmacology, Vol. 10, #O-27-47, 13S.

 

   45.    Post RM, Leverich GS, Ketter TA, Denicoff K, Marangell L, George MS, Pazzaglia PJ, Callahan A, Weiss SRB: The Empirical and Theoretical    Rationales for Lifetime Prophylaxis in Bipolar Affective Illness. XIX CINP Congress, Washington, D.C. 1994, 

 

   46.    Ketter TA, George MS, Andreason PJ, Horwitz BJ, Herscovitch P, Post RM: Positive Correlations Between Procaine-Induced Paralimbic rCBF Increases and Psychosensory and Emotional Experiences. XIX CINP Congress, Washington, D.C. 1994 Neuropsychopharmacology, Vol. 10, #O-84-107, 28S.

 

47.       Ketter TA, George MS, Andreason PJ, Herscovitch P, Post RM: Blunted Paralimbic Resting and Procaine-Activated rCBF in Healthy Females Compared to Males. Biological Psychiatry 1994, Philadelphia, PA.

 

  48.     Pazzaglia PJ, George MS, Post RM, Rubinow DR, Davis C: Increased CSF Somatostatin in Affectively Ill Patients Treated with Nimodipine. XIX CINP Congress, Washington, D.C. 1994. Neuropsychopharmacology, Vol. 10 #P-58-192, 142S.

           

   49.    Marangell L, George M, Callahan A, Pazzaglia P, Ketter T, Post R:        Intrathecal Thyrotropin-Releasing Hormone in the Treatment of Affective Disorders: Preliminary Results of a Clinical Trial. XIX CINP Congress, Washington, D.C. 1994. Neuropsychopharmacology, Vol. 10, #P-174-35, 221S.

 

   50.    Ketter TA, George MS, Andreason PJ, Marangell LB, Pazzaglia PJ, Callahan AM, Parekh P, Herscovitch P, Post RM: Carbamazepine Decreases Regional Cerebral Glucose Metabolism in Affective Disorders and Has Complex Relationships with Mood State. XIX CINP Congress, Washington, D.C. 1994.

                Neuropsychopharmacology, Vol. 10, #O-225-326, 83S.

 

   51.    George MS, Ketter TA, Davis CL, Rubinow DR, Andreason PJ, Pazzaglia PJ, Marangell LB, Callahan AM, Herscovitch P, Horwitz B, Post RM: CSF Somatostatin Correlates with Regional Cerebral Metabolism in Mood-Disorder Subjects. XIX CINP Congress, Washington, D.C. 1994 Neuropsychopharmacology, Vol. 10, P-117-101, 178S.

 

   52.    George MS, Ketter TA, Parekh PI, Horwitz B, Herscovitch P, Cloninger CR, Post RM: Personality Traits Correlate with Resting rCBF. 147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA. New Research #450.

 

   53.    Ketter TA, George MS, Andreason PJ, Parekh P, Pazzaglia PJ, Marangell LB, Callahan AM, Cohen RM, Herscovitch P, Post RM: CMRglu in Unipolar versus Bipolar Depression. 147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA. 

 

54.           Ketter TA, George MS, Andreason PJ, Horwitz B, Parekh P, Pazzaglia PJ, Marangell LB, Callahan  

          AM, Cohen RM, Herscovitch P, Post RM: Depression and Frontal rCMRglu Correlate Inversely.

          147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA.

 

   55.    Greenberg BD, Hoehn-Saric R, George MS, Rubenstein C, Altemus M, Keuler D, Wang L, Murphy DL: Symptom Activation and rCBF in OCD. 147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA. 

 

   56.       Marangell L, Ketter TA, George MS, Pazzaglia PJ, Callahan AM, Andreason PJ, Parekh PI, Horwitz B, Herscovitch P, Post RM: Thyroid Indices and Cerebral Metabolism in Mood Disorders. 147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA. 

 

   57.    Callahan AM, Ketter TA, George MS, Marangell LB, Pazzaglia PJ, Andreason PJ, Parekh PI, Horwitz B, Herscovitch P, Post RM: Cholesterol and Cerebral Metabolism in Mood Disorders.147th Annual Meeting of the American Psychiatric Association, May 22-26, 1994, Philadelphia, PA. 

 

   58.    Post RM, Ketter TA, Denicoff K, Pazzaglia PJ, Marangell L, George MS, Callahan A: Anticonvulsants in Bipolar Illness: State of the Art. Pittsburgh Bipolar Conference, 1994.

  

   59.    George MS, Ketter TA, Parekh PI, Herscovitch P, Post RM: Gender Differences in rCBF During Transient Self-induced Sadness or Happiness. American Neuropsychiatric Association Annual Scientific Meeting. Newport, R.I. July 23, 1994.

 

   60.    George MS: The Clinical Use of SPECT in Depressive Disorders. 148th Annual Meeting of the American Psychiatric Association, May, 1995, Miami, FL. 

 

   61.    Ketter TA, George MS, Parekh PI, Pazzaglia PJ, Marangell LB, Callahan AM, Kimbrell T, Frye MA, Herscovitch P, Post RM: PET Imaging and Psychotropic Response Prediction. 148th Annual Meeting of the American Psychiatric Association, May, 1995, Miami, FL. 

 

   62.    Ketter TA, Pazzaglia PJ, George MS, Marangell LB, Callahan AM, Kimbrell T, Frye MA, Parekh P, Andreason PJ, Herscovith P, Post RM: Baseline Cerebral Hypometabolism May Predict Response to Nimodipine in Mood Disorders. American College of Neuropsychopharmacology 1994, p.149.

 

   63.    George MS, Wassermann EM, Williams W, Steppel J, Pascual-Leone A, Hallet M, Post RM: Rapid Transcranial Magnetic Stimulation (rTMS) in Different Prefrontal Regions Produces Subtle, Sub-Clinical Divergent Mood Changes in Healthy Volunteers. American College of Neuropsychopharmacology 1994, p. 169.

 

64.           George MS, Parekh PI, Rosinsky NI, Ketter TA, Kimbrell TA, Heilman K, Post RM: Right Hemisphere Activation When Listening for Emotional Prosody: An O15 PET Study in Healthy Volunteers. 1995 AAN, Seattle, WA, Neurology 45, 817S, A389.

 

65.           Samii A, Ikoma K, Mercuri B, George MS, Hallet M, Wasserman EM: Decreased Post-Exercise Facilitation 

           of Motor Evoked Potentials in Depressed Patients. 1995 AAN, Seattle, WA, Neurology 45, 807S, A386.

 

66.           Williams W, Steppel J, George MS, Wassermann EM, Pascual-Leone A, Hommer DW, Linnoila M, Hallett M, Post RM: Rapid Transcranial Magnetic Stimulation (rTMS) in Prefrontal Cortex: Mood and Neuroendocrine Effects. 1995 AAN, Seattle WA, Neurology 45, 68P, A178.

 

67.           George MS, Mathe AA, Frye MA, Davis CL, Pazzaglia PJ, Rubinow DL, Jerrels S, Post RM: CSF CGRP   

           Correlates with Neuropeptides in Controls but not Affective Illness. Biological Psychiatry 1995, Miami, FL.

 

 68.       Frye M, Mathe AA, George MS, Pazzaglia PJ, Jerrels S, Post RM: CSF Neuropeptide Y in Mood Disorders and Treatment with Carbamazepine. Biological Psychiatry 1995, Miami, FL.

 

   69.       Kimbrell TA, George MS, Parekh PI, Ketter TA, Herscovitch P, Post RM:      Regional Brain Activity During Self-Induced Anger and Anxiety. Biological Psychiatry 1995, Miami, FL.

 

70.         Mathe AA, George MS, Frye MA, Post RM: Elevated Concentrations of CSF CGRP Might be a Trait    

          Marker of Major Depression. Biological Psychiatry 1995, Miami, FL.

 

71.       Callahan AM, Frye MA, Marangell LB, George MS, Ketter TA, Kimbrell TA, L'Herrou TL, Pazzaglia PJ, Post RM: Differential Mood and Endocrine Effects of Intravenous Vs. Intrathecal TRH. Biological 

          Psychiatry 1995, Miami, FL. 

 

72.           Greenberg BD, George MS, Dearing J, Benjamin J, Altemus M, Karp B, Wassermann ES, Hallett M,

            Murphy DL: Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on Mood, Anxiety and    

            Obsessive Compulsive Symptoms in OCD. New Research Posters and Abstracts, NR 508, p191, 148th 

            Annual Meeting of the American Psychiatric Association, May, 1995, Miami, FL.

 

  73.       George MS, Wassermann ES, Williams WA, Kimbrell TA, Pazzaglia PJ, Callahan A, Frye M, Ketter TA, Hallett M, Post RM: Differential Prefrontal Lobe Rapid Transcranial Magnetic Stimulation (rTMS) in Depression: Preliminary Observations. New Research Posters and Abstracts, NR 313, p139, 148th

              Annual Meeting of the APA, May, 1995, Miami, FL.

 

74.     George MS, Kimbrell TA, Parekh PI, Ketter TA, Pazzaglia PJ, Callahan AM, Frye M, Marangell L,  

 Herscovitch P, Post RM: Actively Depressed Subjects Have Difficulty Inducing, and Blunted Limbic rCBF  Activation During, Transient Sadness. New Research Posters and Abstracts, NR 167, p 99, 148th Annual 

          Meeting of the APA, May, 1995, Miami, FL.

 

75.          George MS, Parekh PI, Willis M, Lalonde F, Ketter TA, Post RM: An fMRI Study of Transient Sadness in Healthy Adult Women - Brain Activity Due to Mood State versus the Effort of Changing Mood. New Research Posters and Abstracts, NR 522, p195, 148th Annual Meeting of the APA, May, 1995.

 

76.          Poltorak M, Wright R, Frye M, George MS, Pazzaglia PJ, Post RM, Hemperly JJ, Jerrels S, Freed WJ: Increased CSF N-CAM in Patients with Bipolar and Unipolar Mood Disorder. New Research Posters and Abstracts, NR 287, p 132, 148th Annual Meeting of the APA, May, 1995, Miami, FL.

 

77.          Devous MD, Thisted RA, Jagust WJ, George MS, Van Heertum RL, Morgan GF: Meta Analysis of SPECT Brain Imaging in Dementia. The Society of Nuclear Medicine 42nd Annual Meeting. Minneapolis MN, June 1995.

 

78.          Wassermann EM, George MS, Williams W, Post RM, Hallett M: Motor performance in depression improves following repetitive transcranial magnetic stimulation (rTMS) of prefrontal cortex. American Neurological Association, October, 1995, Washington, DC.

 

79.         George MS, Wassermann EM, Williams WA, Callahan A, Basser P, Hallett M: Chronic Daily Left Prefrontal Repetitive Transcranial Magnetic Stimulation (rTMS) Improves Mood in Depression. American Neurological Association, October 22-25, 1995, Washington, DC.

 

80.          Samii A, Wassermann EM, Ikoma K, Mercuri B, O'Fallon A, Dale J, George MS, Strauss S, Hallett M: Decreased Post-Exercise Facilitation of Motor Evoked Potentials in Patients with Chronic Fatigue Syndrome and Depression. American Neurological Association, October 22-25, 1995,

                Washington, DC.

 

81.         Greenberg BD, George MS, Wassermann EM, Williams WA, Dearing J, Steppel J, Hallett M, Post RM: Repetitive transcranial magnetic stimulation (rTMS) of Prefrontal Cortex: Mood and Anxiety Effects in Health and Disease. American Neuropsychiatric Association 7th Annual Meeting. October 16, 1995, Pittsburgh, Pennsylvania. J Neuropsychiatry and Clinical Neurosciences 7,3:P15; 402-403.

 

82.          Ketter TA, Kimbrell TA, George MS, Post RM: PET Studies of Illness Heterogeneity and Baseline Markers of Therapeutic Responses in Refractory Depression. Third International Conference in Refractory Depression.       October, 1995.

 

83.          George MS, Ketter TA, Williams W, Wasserman E. Kimbrell TA, Post RM: Multimodal Approaches to Unravelling the Functional Neuroanatomy of Depression - PET, fMRI and Transcranial Magnetic Stimulation Studies in Depressed Subjects and Healthy Controls. American College of Neuropsychopharmacology 1995. p 65.

 

84.         George MS, Ketter TA, Kimbrell TA, Post RM: Brain Imaging in Women with Respect to Mood and Depression. Part of a Scientific Symposium on the Biology of Depression in Women (Dan Oren, chair). 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.

 

85.         George MS, Kimbrell TA, Ketter TA, Post RM: Transient Sadness in Depression and Health. Part of a Scientific Symposium on Functional Neuroimaging in Psychiatry (Jose Pardo, chair). 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.

 

86.         George MS, Williams WA, Wassermann EM, Post RM: rTMS as a Probe of Mood in Health and Disease. Part of a Scientific Symposium on Transcranial Magnetic Stimulation: A Neuropsychiatric Tool for the 21st Century. (Mark George, chair). 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.

 

87.         Greenberg BD, George MS, Dearing J, Wassermann EM, Schlaepfer T, Post RM, Murphy DL. rTMS as a  probe in Obsessive-Compulsive Disorder. Part of a Scientific Symposium on Transcranial Magnetic Stimulation: A Neuropsychiatric Tool for the 21st Century. (Mark George, chair). 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.

 

88.         Ketter TA, George MS, Kimbrell TA, Stein RM, Frye MA, Cora-locatelli G, Post RM: Anterior Paralimbic Dysfunction in Mood Disorders. Part of a Scientific Symposium on 'New Development of PET Imaging in Psychiatry'. (Marc Laruelle, chair). 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.

 

89.         George MS, Ketter TA, Mathe AA, Kimbrell TA, Frye M, Willis M, Benson B, Little JT, Stein R, Post RM: Mapping Neurochemistry onto Neuroanatomy: Correlations Between Resting rCBF and CSF Monoamine Metabolites. American College of Neuropsychopharmacology 1995, p.226.

 

90.         Ketter TA, George MS, Kimbrell TA, Stein RM, Willis MW, Little JT, Frye MA, Cora-Locatelli G, Benson BE, Herscovitch P, Post RM: Assessment of PET Data in Individual Patients with Mood Disorders. American College of Neuropsychopharmacology 1995, p.230.

 

91.         Ketter TA, Kimbrell TA, George MS, Stein RM, Willis MW, Benson BE, Frye MA, Cora-locatelli G, Post RM: Baseline Hypermetabolism May Predict Carbamazepine Response, and Hypometabolism Nimodipine Response in Mood Disorders. CINP, Australia, 1996.

 

92.         Frye MA, Mathe AA, Gary KA, George MS, Huggins T, Cora-Locatelli G, Pazzaglia PJ, Davis C, Rubinow D, Winokur A, Post RM. CSF Neuropeptide Dysregulation in Patients with Affective Disorder. Biological Psychiatry 1996,39:596. New York, NY.

 

93.         Ketter TA, George MS, Kimbrell TA, Stein RM, Willis MW, Benson BE, Frye MA, Cora-locatelli G, Post RM: Prefrontal and anterior paralimbic dysfunction in primary and secondary mood disorders: Evidence of common neural substrates. 8th Congress of the Association of European Psychiatrists. London, July 7-12, 1996.

 

94.          Beale MD, Kellner C, Gordan B, Spicer K, George MS: Ictal Brain SPECT in Patients Undergoing ECT. 1996 Association of Convulsive Therapy Scientific Program Abstract, May, New York, NY.

 

95.         Callahan AM, Marangell LB, Frye MA, George MS, Ketter TA, L'Herou T, Pazzaglia PJ, Post RM: Comparative Mood and Endocrine Effects of Intravenous vs Intrathecal TRH. American College of Neuropsychopharmacology 1995, p.153.

 

96.        Greenberg BD, George MS, Benjamin J, Dearing J, Wassermann EM, Schlaepfer TE, Post RM, Murphy DL: Repetitive Transcranial Magnetic Stimulation as a probe in obsessive-compulsive disorder. American College of Neuropsychopharmacology 1995, p.156.

 

97.          George MS: Rapid Transcranial Magnetic Stimulation (rTMS) - A Potential New Neuropsychiatric Treatment.  Part of a scientific program on 50 years of Somatic treatments in psychiatry.  Biological Psychiatry 1996;39:512. New York, NY.

 

98.        Kimbrell TA, Ketter TA, George MS, Stein RS, Danielson A, Willis M, Post RM: Anterior Paralimbic Hypometabolism in Patients with Unipolar Depression in Remission.  New Research Poster and Abstracts # 462, 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.p. 196.

 

99.               Kimbrell TA, Willis MW, Ketter TA, George MS, Andreason PJ, Stein RS, Danielson A, Benson B, Post RM: Increased Basal Ganglia, Thalamic and Anterior Cingulate Metabolism in Women Compared to Men. New Research Poster and Abstracts #463, 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.p. 196.

 

100.        Frye MA, Kimbrell TA, Mathe AA, George MS, Ketter TA, Willis M, Stein R,  Danielson A, Post RM: Neuroimaging Neuropeptide Correlation: CGRP and FDG PET. New Research Poster and Abstracts, 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.

 

101.       Dearing JE, George MS, Greenberg BE, Wassermann EM, Schlaepfer TE, Post RM: Effects of Prefrontal rTMS on Mood and Anxiety in Healthy Volunteers: A Replication Study. New Research Poster and Abstracts NR 182, 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY. p. 116.

 

102.      George MS, Wassermann EM, Williams WA, Kimbrell TA, Little JT, Hallett M, Post RM: Daily Left Prefrontal rTMS in Outpatient Depression: Initial     results of a double-blind placebo controlled trial. New Research Poster and Abstracts #768, 149th Annual Meeting of the American Psychiatric Association, May, 1996, New York, NY.p. 280-281.

 

103.       Vincent DJ, Halford J, Steedman J, Wright AC, Webb J, Pecheny A, Bohning DE, Frey D, Cure J, Horton J, Young J, Dannels WR, George MS: An Initial Clinical Study Using Echoplanar BOLD fMRI to Determine Language Location by Hemisphere. 2nd International Conference on Functional Mapping of the Human Brain, June 17-21, 1996, Boston, MA.

 

104.       Bohning DE, Wright AC, Pecheny AC, George MS: Repeatability of Spin label-based In-vivo Perfusion Maps. 2nd International Conference on Functional Mapping of the Human Brain, June 17-21, 1996, Boston, MA.

 

105.       George MS, Kimbrell TA, Ketter TA, Post RM: Transient Sadness in Depression and Health. X World Congress of Psychiatry, Aug 23-28, 1996, Madrid, Spain.

 

106.        Sallee FR, Vrindavanam NS, George MS, Hamamdzic SA, Ma JX: The Functional Effect of the Second Transmembrane Leucine Zipper Motif of the Dopamine Transporter. Neuroscience 1996, Washington, DC.

 

107.      Vincent DJ, Bryant AE, Roberts DR, Halford JJ, Worthington WC, Vera CL, George MS: Preliminary Results of Multimodality Presurgical Evaluation for Intractable Epilepsy. Society For Neuroscience 1996, Washington, DC.

 

108.      George MS, Wassermann EM, Kimbrell T, Speer AM, Stallings L, Roberts D, Vincent D, Beale M, Cheng K, Spicer K: An Overview of Initial Studies Combining Conventional Functional Imaging (PET, SPECT, fMRI) with Transcranial Magnetic Stimulation (TMS) to Actively Probe Brain-Behavior Relationships. J Neuropsychiatry Clin Neuroscience, 1997;9:131, poster 6.

 

109.       Speer AM, Risch SC, Sallee FR, Beale MD, Kellner CH, Ballenger JC, George MS: Mood Effects of Lateralized Prefrontal Repetitive Transcranial Magnetic Stimulation (rTMS) in Healthy Controls: The Importance of Frequency. J Neuropsychiatry Clin Neuroscience, 1997;9:154,P85.

 

110.       Greenberg BD, Dearing J, George MS, Wassermann EM, Grafman J, Kimbrell T, Jacobsen F, Post RM, Murphy DL: Repetitive Transcranial Magnetic Stimulation (rTMS) of Prefrontal Cortex in Depression: Effects of a Single rTMS Session. J Neuropsychiatry Clin Neurosc. 1997;9:143,#P43.

 

111.       George MS, Wassermann EM, Speer AM, Kimbrell TA, Stallings L, Vincent DJ,         Roberts DR, Epstein CM: Beyond Functional Imaging: Combining Functional         Imaging (SPECT, PET, fMRI) with Transcranial Magnetic Stimulation (TMS)         to Actively Probe Brain-Behavior Relationships. 150th Annual Meeting of          the American Psychiatric Association, May, 1997, San Diego, Cal.Paper #    46, p. 19.

 

112.        Ketter TA, George MS, Kimbrell TA, Little JT, Post RM: Brain Imaging in Bipolar Disorders. 150th Annual Meeting of the American Psychiatric Association, May, 1997, San Diego, Cal.

 

113.      Ketter TA, George MS, Kimbrell TA, Little JT, Frye MA, Cora-locatelli G, Post RM: Preliminary Evidence of Prefrontal and Anterior Paralimbic Baseline Markers of Psychotropic Responses in Mood Disorders.American         College of Neuropsychopharmacology 1996, San Juan, PR.

 

114.      Ketter TA, Kling MA, George MS, Kimbrell TA, Lefter L, Willis MW, Benson BE, Herscovitch P, Post RM: Relationships Between Procaine-Induced Increases in CBF and Cortisol, ACTH, and Prolactin in Healthy Volunteers.          American College of Neuropsychopharmacology 1996, San Juan, PR.

           

115.      George MS, Cloninger CR, Kimbrell TA, Willis M, Parekh PI, Danielson A, Ketter TA, Herscovitch P, Post RM: Toward the Neurobiological Basis of Temperament: PET Studies of Cloninger's Tridimensional Scale in Healthy Adults.American College of Neuropsychopharmacology 1996, San Juan, PR.

 

116.      Wassermann EM, Kimbrell TA, George MS, Danielson AL, Herscovitch P, Hallet M, Post RM: Local and distant changes in cerebral glucose metabolism during repetitive transcranial magnetic stimulation. 1997 Meeting of the American Academy of Neurology. Neurology

 

117.      Vincent DJ, Roberts DR, Speer AM, Bohning DE, George MS: Merging Methodologies: Mapping Motor Cortex with Echoplanar BOLD fMRI and        Transcranial Magnetic Stimulation. International Society for Magnetic Resonance in Medicine Fifth Scientific Meeting, April, 1997, Vancouver, BC.

 

118.      Stallings LE, Speer AM, George MS, Spicer K, Cheng KT: Neurolite SPECT Imaging as a Predictor of Treatment Response to Repetitive Transcranial Magnetic Stimulation. 44th Annual Meeting of the Society of Nuclear Medicine June 1997, San Antonio, TX.

 

119.      Speer AM, Upadhyaya V, Bohning DE, Vincent DJ, George MS: New Windows into Bipolar Illness: Serial Perfusion MRI Scanning in Rapid Cycling Bipolar Patients. 150th Annual Meeting of the American Psychiatric Association, May, 1997, San Diego, Cal NR 168, p. 111.

 

120.      Stallings LE, Speer AM, Spicer KM, Cheng KT, George MS: Combining SPECT and Repetitive Magnetic Stimulation (rTMS) - Left Prefrontal Stimulation            Decreases Relative Perfusion Locally in a Dose-Dependent Manner. 3rd International Conference on Functional Mapping of the Human Brain (May 1997). Neuroimage 1997;5,4:S521.

 

121.      George MS, Speer AM, Stallings LE, Bohning DE, Roberts DR, Vincent DJ, Epstein CM, Wassermann EM, Kimbrell TA: Beyond Functional Imaging: Combining Functional Imaging (SPECT, PET, fMRI) with Transcranial Magnetic Stimulation (TMS) to Actively Probe Brain-Behavior Relationships. 3rd International Conference on Functional Mapping of the Human Brain (May 1997).Neuroimage 1997;5,4:S519.

 

122.           Vincent DJ, Dubno JR, Horwitz AR, George MS: An Auditory fMRI Study Comparing Passive and Active Listening to Speech. 3rd International Conference on Functional Mapping of the Human Brain (May 1997). Neuroimage 1997;5,4:S189.

 

123.       Bohning DE, Pecheny AP, Epstein CM, Speer AM, Vincent DJ, George MS: In-Vivo Three Dimensional Transcranial Magnetic Stimulation (TMS) Field Mapping with MRI. 3rd International Conference on Functional Mapping of the Human Brain (May 1997).Neuroimage 1997;5,4:S522.

 

124.      Bohning DE, Speer AM, Pecheny AP, Vincent DJ, George MS: Acetazolamide-induced perfusion changes measured with MR spin-labeling. 3rd International Conference on Functional Mapping of the Human Brain (May 1997).Neuroimage 1997;5,4:S380.

 

125.      Bohning DE, Epstein CM, Vincent DJ, George MS: Deconvolution of transcranial magnetic stimulation (TMS) maps. 3rd International Conference on Functional Mapping of the Human Brain (May 1997). Neuroimage 1997;5,4:S520.

 

126.      Wassermann EM, Weegartner F, George MS, Chen R: Decreased Excitability in the Unstimulated Hemisphere After 1 Hz Repetitive Transcranial Magnetic Stimulation. International Clinical Neurophysiology Meeting, Florence, Italy 1997.

 

127.      Adinoff B, Devous MD, George MS, Best S, Alexander D: SPECT Following IV Procaine in Cocaine Addiction. CPDD 1997.

 

128.      Kimbrell TA, Wassermann EM, George MS, Dunn R, Danielson AL, Benson BE, Post RM: Regional Decreases in Glucose Metabolism with Prefrontal Transcranial Magnetic Stimulation (TMS): a new technique for tracing functional brain networks. Neuroscience 1997.

 

129.       Fox PT, Ingham R, George MS, Mayberg HS, Ingham J, Roby J, Martin C, Jerabek P: Imaging Human Intra-Cerebral Connectivity by PET/TMS.Neuroscience 1997.

 

130.       George MS, Speer AM, Stallings L, Wassermann EM, Kimbrell TA, Epstein C, Risch SC, Post RM: Combining TMS with Functional Imaging. Biol Psychiatry 1997; 41:76S #261.

 

131.         Kimbrell TA, George MS, Danielson AL, Dunn RT, Benson BE, Little JT, Herscovitch P, Hallett M, Post RM, Wassermann EM: Changes in Cerebral Metabolism during Transcranial Magnetic Stimulation. Biol Psychiatry 1997; 41: 108S, # 374.  

 

132.        Frye MA, Kimbrell TA, Willis MW, Ketter TA, George MS, Pazzaglia PJ, Dunn RT, Luckenbaugh D, Huggins T, Little JT, Vanderham L, Danielson A, Benson B, Davis C, Rubinow D, Post RM: Low CSF Somatostatin and Cerebral Hypometabolism in Depression. Biol Psychiatry 1997; 41: 32S, #111.

 

133.         Frye MA, Pazzaglia PJ, Luckenbaugh D, Kimbrell TA, Little JT, Dunn RT, George MS, Huggins T, Vanderham L, Leverich GS, Davis C, Rubinow DR, Post RM: Baseline CSF Somatostatin Predictive of Nimodipine Treatment Response. Biol Psychiatry 1997; 41: 33S, #112.

 

134.        George MS, Bohning DE, Shastri A, Nahas Z, Lorberbaum J, Vincent DJ, Roberts DR, Lawandales CC, Speer AM, Risch SC, Ballenger JC: Initial   Studies Combining Transcranial Magnetic Stimulation (TMS) with MRI. American College of Neuropsychopharmacology 1997, Kamuela, Hawaii. 

 

135.         Vincent DJ, Chandler VM, Roberts DR, George MS : Presurgical Mapping of Motor Cortex Using     

             Functional MRI. 98Th Annual American Roentgen Ray Society Meeting, San Francisco, April 26, 1998. 

 

136.         Risch SC, Hamner M, Speer A, Schenckler J, Molloy M, DeVane CL, George MS: Preliminary MRI  

Volumetric Studies of Caudate Volume Before and After Atypical Antipsychotics in Schizophrenia Patients. American College of Neuropsychopharmacology 1997, Kamuela, Hawaii.

 

137.         Brewerton TD, Nahas Z, Molloy M, Risch SC, George MS: Transcranial Magnetic Stimulation (rTMS) in  a  Woman with Major Depression and Bulimia Nervosa. Eighth New York International Conference on            

            Eating Disorders.

 

138.          Bohning DE, Shastri A, Nahas Z, Lorberbaum JP, Danels WR, Vincent DJ, George MS: Interleaved                 Transcranial Magnetic Stimulation (TMS) and fMRI. International Society for Magnetic Resonance in   Medicine Sixth Scientific Meeting, Sydney Australia, April 1998.

 

139.     Vincent DJ, Bryant AE, Worthington WC, Chandler VM. Roberts DR, Wagner MT, Vera CL, George MS: When can fMRI replace the Wada Test for Language Localization? International Society for Magnetic            Resonance in Medicine Sixth Scientific Meeting, Sydney Australia, April 1998.

 

140.     Lorberbaum JP, Newman JD, Horwitz AR, Dubno JR, Nahas Z, Teneback C, Johnson MR, Lydiard RB,            Ballenger JC, MacLean PD, George MS: Functional MRI of Mothers Responding to Infant Cries.   Biological Psychiatry 1998; 43, 85: 25s, #80.

 

141.        Nahas Z, Speer AM, Lorberbaum JP, Molloy M, Liberatos C, Risch SC, George MS: Safety of rTMMRI scans before and after 2 weeks of daily left prefrontal rTMS for Depression. Biological Psychiatrty 43, 85: 95s, #316.

 

142.     Nahas Z, Speer AM, Molloy M, Arana GW, Risch SC, George MS: Preliminary Results Concerning the          Roles of Frequency and Intensity in the Antidepressant Effect of Daily Left Prefrontal rTMS. Biological Psychiatry 1998; 43, 85: 94s, #315.

 

143.     Nahas Z, Stallings LE, Speer AM, Teneback C, Vincent DJ, Bohning DE, Spicer KM, Cheng KT, Molloy         M, Risch SC, George MS: Perfusion SPECT Studies of rTMS Effects on Blood Flow in Health and Depression. Biological Psychiatry 1998; 43, 85: 19s, #63.

 

144.     George MS, Teneback CC, Moore J, Stallings LE, Anton R, Malcolm R: Effect of Past Detoxification History on Human Brain Activity in the Immediate Post-Detoxification Period as Determined by SPECT Scanning. 1998 Research Society on Alcoholism Annual Scientific Meeting. Hilton Head Island, SC June 20, 1998. Alcoholism: Clinical and Experimental Research.

 

145.     Speer AM, Stallings LA, Nahas Z, Lorberbaum JP, Teneback CC, Molloy M, Risch SC, Bohning DE, Ballenger JC, Luckenbaugh D, Wassermann EM, Kimbrell TA, Post RM, George MS. Lack of Autonomic and Cognitive Side Effects of Daily Left Prefrontal rTMS: Preliminary Data. 1998 Annual Meeting of the American Psychiatric Association, Toronto, Canada.

 

146.     Sackeim H (Chair), George MS, (Co-chair), Belmaker RH, Grunhaus L, Pascual-Leone A: Symposium: Antidepressant Effects of rTMS: Who, How and Why. Biological Psychiatry 1998; 43, 85: 75s.

 

147.     George MS, Nahas Z, Speer AM, Avery D, Molloy M, Risch SC, Lorberbaum JP, Bohning DE,

            Post RM: How Does TMS Improve Depression: Current Hints About the Role of Intensity, Frequency,           Location and Dose. Biological Psychiatry 1998; 43, 85: 76s, #253.

 

148.     Bohning DE, Shastri A, Nahas Z, Lorberbaum JP, Andersen SW, Dannels WR, Haxthausen EU, Vincent DJ, George MS: Transcranial Magnetic Stimulation (TMS) During fMRI. 4th International Conference on Functional Mapping of the Human Brain (June 1998).Neuroimage 1998.; 7, 4: S685.

 

149.     Vincent DJ, Ross DA, George MS: Language Lateralization: Development and Preliminary fMRI Testing        of a New Semantic Model. 4th International Conference on Functional Mapping of the Human Brain (June          1998).Neuroimage 1998; 7, 4: S146.

 

150.     Vincent DJ, Bryant AE, Worthington WC, Chandler VM, Roberts DR, Vera CL, Patel SJ, Bohning DE, George MS: When can fMRI replace Wada for Language Localization? Two years experience. 4th International Conference on Functional Mapping of the Human Brain (June 1998).Neuroimage 1998; 7, 4: S147.

 

151.     Shastri A, Bohning DE, George MS: Interleaving Transcranial Magnetic Stimulation with Steady State Magnetic Resonance Imaging of the Brain. 4th International Conference on Functional Mapping of the Human Brain (June 1998).Neuroimage 1998; 7, 4: S686.

 

152.     Lorberbaum JP, Newman JD, Dubno JR, Horwitz AR, Nahas Z, Teneback C, Johnson MR, Lydiard RB, Ballenger JC, George MS: Feasibility of Using fMRI to Study Mothers Responding to Infant Cries. 4th International Conference on Functional Mapping of the Human Brain (June 1998).Neuroimage 1998; 7, 4: S907.

 

153.     Nahas Z, Stallings LE, Speer AM, Teneback C, Vincent DJ, Bohning DE, Spiner KM, Cheng KT, Molloy M, Risch SC, George MS: Two Weeks of Daily Left Prefrontal rTMS Further Reduces Prefrontal and Cingulate Blood Flow in Depressed Patients. 4th International Conference on Functional Mapping of the Human Brain (June 1998).Neuroimage 1998; 7, 4: S929.

 

154.     George MS, Bohning DE, Shastri A, Nahas Z, Lorberbaum JP, Speer AM, Vincent DJ: Using Functional         Imaging to Understand the Neurobiological Effects of TMS. College Internationale          Neuropsychopharmacology July 12-16, 1998 Glasgow, Scotland

 

155.     Frye MA, Gary KA, Little JT, Kimbrell TA, Huggins T, Dunn RT, George MS, Osuch E, Speer AM, Callahan AM, Cora-Locatelli G, Vanderham E, Winokur A, Post RM: Gender Differences in CSF TRH. 1998 Annual Meeting of the American Psychiatric Association, Toronto, Canada.

 

156.     Frye MA, Klee GG, Little JT, Kimbrell TA, Huggins T, Dunn RT, George MS, Cora-Locatelli G, Osuch E, Speer AM, Roddy D, Vanderham E, Post RM: Positive Relationship of Thyroid Indices and Severity of Depression. 1998 Annual Meeting of the American Psychiatric Association, Toronto, Canada.

 

157.     George MS, Bohning DE, Nahas Z, Shastri A, Lorberbaum J, Vincent DJ: COMBINING rTMS AND    fMRI TO UNDERSTAND MECHANISMS. Part of a symposium on ‘Mechanisms of the Psychotropic   Effect of Repetitive Transcranial Magnetic Stimulation’ Ulf Ziemann and Goran Hajak, Chairs; XI World Congress of Psychiatry, Hamburg, Germany, August 6-11, 1999

 

158.     Mirski D, Greenshields AJ, Mintzer J, Lawrence H, Speer AM, Nahas Z, Bohning DE, Liberatos C, George      MS: Perfusion Studies of Patients with Alzheimer' Disease. American Association of Geriatric Psychiatry     Annual Meeting, San Diego1998.

 

159.     George MS, Bohning DE, Nahas Z, Shastri A, Lorberbaum JP, Speer AM, Vincent DJ, Roberts D, Stallings LE, Teneback C, Blumenthal K: Functional Neuroimaging Studies of TMS: SPECT, PET and fMRI. 11Th Congress of the European College of Neuropsychopharmacology, Paris, France, November, 1998.

 

160.     George MS, Nahas Z, Bohning DE, Shastri A, Lorberbaum J, McConnell K, Vincent DJ: Using fMRI to Understand TMS Effects on Prefrontal Cortex.  1999 Annual Meeting of the American Psychiatric Association, Washington, DC.

 

161.     Nahas Z, Blumenthal K, Risch SC, Molly M, Christie S, Arana GW, George MS: Does One Day of Left Prefrontal rTMS Modify Mood or Facial Affect (Negative Symptoms) in Schizophrenia? 1999 Annual Meeting of the American Psychiatric Association, Washington, DC.

 

162.        George MS, Nahas Z, Speer AM, Liberatos C, Upadhyaya V, Bohning DE, Shastri A, Risch SC: Ser Perfusion MRI Scanning In Rapid Cycling Bipolar Disorder. American College of  Neuropsychopharmacology (ACNP) Panel Presentation as part of a symposiom on ‘The Neuropathology of Bipolar Disorder’ Dec. 1998,   Las Croabas, PR.

 

163.     Anton RF, Teneback C, Bloomer C, Drobes D, Nahas Z, Lorberbaum J, Vincent DJ, George MS:           Neuroanatomical Correlates of Cue-Induced Alcohol Craving, American College of   Neuropsychopharmacology (ACNP) Poster, Dec. 1998, Las Croabas, PR.

 

164.     Risch SC , Nahas Z, Molloy M, Owens SD, Hamner M, DeVane CL, George MS:  An MRI Volumetric              Study Of Caudate Volume Before And After Atypical Antipsychotics In Schizophrenia Patients. American        College of Neuropsychopharmacology (ACNP) Poster, Dec. 1998, Las Croabas, PR.

 

165.     George MS, Shastri A, McConnell KA, Nahas Z, Lorberbaum JP, Roberts DR, Teneback C, Vincent DJ,           McGavin L, Bohning DE: A Combined TMS/fMRI Study Of Intensity-Dependent TMS Over Motor Cortex.            American College of Neuropsychopharmacology (ACNP) Poster, Dec. 1998, Las Croabas, PR.

 

166.     Vincent DJ, Roberts DR, Ross DA, George MS: Language Localization for Presurgical Planning for Epilepsy Patients: fMRI, WADA and Paradigm Testing. 1998 International Symposium on Functional Neuroimaging in the Epilepsies, November, 1998, Atlanta, GA.

 

167.     Roberts DR, Vincent DJ, Ross DA, George MS: Language Localization for Presurgical Planning for Epilepsy Patients: A Case Study Using fMRI and Wada. 1998 International Symposium on Functional Neuroimaging in the Epilepsies, November, 1998, Atlanta, GA.

 

168.     Nahas Z, Speer AM, Molloy M, Oliver NC, Arana GW, Ballenger JC, Risch SC, George MS: Role Of   Stimulation Frequency In The Antidepressant Effect Of Left Prefrontal rTMS. Biological Psychiatry 1999:    45: 79S, #256.

 

169.     Nahas Z, McConnell K, Collins S, Molloy M, Oliver NC, Risch SC, Christie S, Arana GW, George MS:             Could Left Prefrontal rTMS Modify Negative Symptoms And Attention In Schizophrenia? Biological         Psychiatry 1999;45:37s, #120.

 

170.     Teneback C, Nahas Z, Speer AM, Molloy M, Stallings LE, Vincent DJ, Bohning DE, Spicer KM, Cheng KT, Risch SC, George MS: Baseline Paralimbic Activity Declines with Depression Severity and Is

            Associated with rTMS Response. Biological  Psychiatry 1999; 45: 132S, #428.

 

171.     Kozel A, Nahas Z, DeDrux C, Molloy M, Lorberbaum JP, Risch SC, George MS: Scalp to prefrontal     cortex distance increases with age and might influence the antidepressant effect of left prefrontal rTMS.      American Psychiatric Association 1999 Annual Meeting. Washington, DC. New Research Program and              Abstracts p. 112, #NR 181.

 

172.     Ketter TA, Kimbrell TA, George MS, Dunn RP, Speer AM, Willis MW, Benson BE, Danielson A, Frye MA, Herscovitch P, Post RM: Effects of mood state, illness subtype and course on cerebral glucose metabolism in bipolar disorders. Third International Conference on Bipolar Disorder. Pittsburgh, PA. June 17-19, 1999.

 

173.     Bohning DE, Shastir A, Wassermann EM, Ziemann U, Lorberbaum J, Nahas Z, Lomarev MP, George               MS: BOLD-fMRI Response to Single Pulse Transcranial Magnetic Stimulation (TMS). American           Association Of Physicists in Medicine. 1999.

 

174.     Shastri A, Lomarev M, George MS, Bohning DE: A Method for Acquiring Skin Conductance Measurements During Functional Magnetic Resonance Imaging. American           Association Of Physicists in Medicine. 1999.

 

175.     Adinoff B, Devous MD, George MS, Best S, Alexander D, Payne K: IV Procaine and Limbic Activation (SPECT) in Cocaine Addicts. Biological Psychiatry 1999;45:53S, #169.

 

176.     Hamner MB, Ulmer HG, Horne DF, George MS, Arana GW: Procaine Administration in PTSD: A Pilot Study of Tolerability. Biological Psychiatry 1999;45: 90S, #295.

 

177.     George MS, Insel T, Leckman J, Lorberbaum, Baxter LR, Schlaepfer T, MacLean PA: The Limbic System in Complex Mammalian Behaviors: Studies Stemming for the Life Work of Dr. Paul MacLean. Biological Psychiatry 1999;45: 97S, #316.

 

178.     Osuch EA, Ketter TA, Kimbrell TA, George MS, Benson SE, Willis MW, McCann U, Post RM: Regional Cerebral Metabolism Unique to Anxiety Symptoms in Affective Disorder Patients. Biological Psychiatry 1999;45: 129S, #417.

 

179.     Risch SC, Nahas Z, Hamner MB, Molloy M, Devane CL, Owens SD, George MS: MRI Volumetric Studies of Atypical Antipsychotics. American Psychiatric Association 1999 Annual Meeting. Washington, DC. New Research Program and Abstracts p. 133, #NR 248.

 

180.        George MS, Nahas Z, Lorberbaum JP, Shastri A, McConnell KA, Roberts DR, Teneback C, Vincent DJ, Lomarev M, Bohning DE:  New Findings from Interleaved Transcranial Magnetic Stimulation and  

           Functional MRI. American College of Neuropsychopharmacology (ACNP) Poster, Dec. 1999, Mexico.

           

181.     Rush AJ, George MS,  Marangell LB, Sackeim HA, Husain MM, Nahas Z, Lisanby SH, Burt T, Giller C,           Haines S, Simpson RK, Goodman RR:  A Pilot Study Of Vagus Nerve Stimulation (Vns™) For Treatment-             Resistant Depressions. American College of Neuropsychopharmacology (ACNP) Poster, Dec. 1999,           Mexico.

 

182.     Risch SC, Nahas Z, Horner MD, McGurk SR, Molloy M, Goldman J, Gilliard C, Owens SD, Christie S, Markowitz JS, DeVane CL, Mintzer J, George MS: Donepezil Augmentation of Antipsychotics in             Schizophrenia: Cognitive and fMRI Effects. American College of Neuropsychopharmacology (ACNP)           Mexico.

 

183.     Lorberbaum JP, George MS, Johnson MR, Emmanuel NP, Book SW, Mintzer O, MortonA, Nahas Z,   Bohning DE, Vincent D, Shastri A, Hamner M, Arana GW,  Ballenger JC, Lydiard RB. Feasibility of using        fMRI in Social Phobics undergoing a Public Speaking Task. Biological Psychiatry 1999; 45:8s, #429.

 

184.     Goldman J, Horner M,Nahasz, Palecko S, Kelly S, Devane CL, George MS, Risch SC: Donepezil Augmentation for Cognitive Impairment in Euthymic Patients. Biological Psychiatry 2000 (abstract).

 

185.     Lorberbaum JP, Emmanuel NP, Mintzer O, Kapp R, Crawford M, Morton A, Johnson MR, Book SW, Hamner M, Nahasz, Arana GW, Ballenger JC, Lydiard RB, George MS: Changes in Anxiety after Prefrontal rTMS in Patients with GAD. Biological Psychiatry 2000 (abstract).

 

186.     Lorberbaum JP, Newman JD, Horwitz AR, Dubno JR, Hamner M, Bohning DE, Shastri A, Ballenger JC, Lydiard RB, George MS: Activating Brain Regions Involved In Social Attachment. Biological Psychiatry 2000 (abstract).

 

187.     Lomarev M, Shastri A, Ziemann U, Wassermann EM, McConnell KA, Nahas Z, Lorberbaum JP, Vincent         DJ, George MS, Bohning DE: Can Interleaved TMS and fMRI Demonstrate Changes In an Activated              Circuit? Biological Psychiatry 2000 (abstract).

 

188.     Nahas Z, Oliver NC, Johnson M, Molloy M, Hughes PL, Ballenger JC, Risch SC, George MS: Feasibility and Efficacy of Left Prefrontal rTMS as a Maintenance Antidepressant. Biological Psychiatry 2000 (abstract).

 

189.     George MS, Nahas Z, Oliver NC,Molloy M, Kozel FA, Lorberbaum JP, Lomarev M, Li X: Recent Advances in TMS as an Antidepressant. Part of a symposium on ‘An Update on New Somatic Treatments for Depression’ (M. George Chair). Biological Psychiatry 2000 (abstract).

 

190.     Rush AJ, George MS, Marangell LB, Sackeim HA, Husain MM, Nahas Z, Burt T, Giller C, Haines S, Simpson RK, Goodman RR: Vagus Nerve Stimulation For Treatment-Resistant Depression. Part of a symposium on ‘An Update on New Somatic Treatments for Depression’ (M. George Chair). Biological Psychiatry 2000 (abstract).

 

191.     Bohning DE, Shastri A, Lomarev MP, Nahas Z, Lorberbaum JP, Denslow S, George MS:  Interleaved Transcranial Magnetic Stimulation  (TMS) and Bold fMRI as a New Tool to Image and Test Brain Circuits    and Behavior. Part of a symposium on ‘ Beyond Correlational Imaging: Combining Funcational Imaging           with Brain Stimulation as New Neuroscience Tools’ (M George, Chair). American College of    Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico.

 

192.     George MS, Nahas Z, Lomarev M, Denslow S, Oliver NC, Shastri A, Bohning DE: Using Interleaved Vagus Nerve Stimulation (VNS) and BOLD fMRI to Examine Regional Brain Effects in Depressed Adults. Part of a symposium on ‘ Beyond Correlational Imaging: Combining Funcational Imaging          with Brain Stimulation as New Neuroscience Tools’ (M George, Chair). American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico.

 

193.     Marangell LM, George MS, Hussain MM, Johnson CR, Nahas Z, Burt T, Sackeim HA, Rush AJ: Long-           term experience with vagus nerve stimulation (VNS) for the             treatment of resistant depressions. Poster,        American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico (p. 164).

 

194.     Nahas Z, Risch SC, Horner MD, Markowitx JS, Li X, Lorberbaum JP, McGurk S, Devane L, George MS: Augmenting an Atypical Antipsychotic with a Cognitive Enhancer (Donepezil) Improves Regional Brain Activity in Schizophrenia Patients: A Double-Masked Placebo Controlled BOLD phMRI Study. Poster, American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico (p. 136).

 

195.     Adinoff B, Devous MD, Best SM, George MS, Alexander D. Payne JK: Orbitofrontal Dysfunction in Cocaine Addiction: SPECT Following IV Procaine. Part of a symposium on ‘ Addiction as a Disease of the Orbitofrontal Cortex’ (R. Anton, Chair). American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico.

 

196.     Anton RF, Moak DH, Latham PK, Drobes DJ, George MS: Similarities Between Addiction and Obsessive Compulsive Traits: Brain and Behavioral Features. Part of a symposium on ‘ Addiction as a Disease of the Orbitofrontal Cortex’ (R. Anton, Chair). American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico.

 

197.     Kozel FA, Revell L, Lorberbaum JP, Shastri A, Nahas Z, Bohning DE, George MS: Regional Brain Correlates of Deception: A Pilot fMRI Study in Healthy Young Adults. Poster, American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico (p. 138).

 

198.     Risch SC, Nahas Z, Horner MD, McGurk SR, Goldman J, Palecko S, Molloy M, Christie S, Markowitz JS, DeVane CL, Mintzer J, George MS: Donepezil Augmentation of Antipsychotics in Schizophrenia: Cognitive and fMRI Effects. Poster, American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico (p. 200).

 

199.     Sackeim HA, Rush AJ, George MS, Marangell LB. Burt T, Hussain MM, Nahas Z, John CR: Vagus Nerve Stimulation (VNS) in Outpatients With Treatment-Resistant Depression. Poster, American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico (p. 311).

 

200.     Lorberbaum JP, George MS, Johnson MR, Emmanuel NP, Mintzer O, Book SW, Morton A, Crawford-Cisa M, Kapp R, Hamner MB, Ballenger JC, Lydiard RB: Brain Activity in Social Phobics Undergoing a Public Speaking Task. Poster, American College of Neuropsychopharmacology (ACNP) 39th Annual Meeting, Dec. 12, 2000, San Juan, Puerto Rico (p. 319).

 

201.     Nahas Z, Risch SC, Horner MD, Markowitz JS, LI X, Lorberbaum JP, McGurk S, DeVane CL, George   MS: Augmenting an Atypical Antipsychotic with a Cognitive Enhancer (Donepezil) Improves Regional       Brain Activity in Schizpohrenia Patients: A Double-Blind Placebo Controlled Bold phMRI Study. In      Biological Psychiatry 2001, 49: #100, 29S.

 

202.     Marangell LB, Rush AJ, George MS, Johnson CR, Nahas Z, Husain MM, Burt T, Sackeim HA: Long- Term Expreience with Vagus Nerve Stimulation (VNS) for Treatment Resistant Depression. In Biological    Psychiatry 2001, 49: #322, 93S.  

 

203.     Husain MM, Sackheim HA, Rush AJ, George MS, Marangell LB, Burt T, Nahas Z, Johnson CR:          Expanded Acute Expreience with Vagus Nerve Stimulation (VNS) in the Treatment of Resistant Depression.          In Biological Psychiatry 2001, 49: #357,103S.

 

204.     Chae JH, Oliver NC, Nahas Z, Li X, Benjamin B, Sallee FR, George MS: Does Transcranial Magnetic   Stimulation (TMS) Over Motor or Prefrontal Cortex Modify Tics in Patients with Tourette’s Syndrome? A      Pilot Study. In Biological Psychiatry 2001, 49: #394, 13S.

 

205.     Nahas Z, Denslow S, Lomarev M, Oliver NC, Shastri A, Bohning DE, George MS: Interleaved Vagus Nerve Stimulation (VNS) and fMRI in Depression: A New Investigative Technology. In Biological               Psychiatry 2001, 49: #522, 152S.

 

206.     Teneback CC, George MS, Li X, Nahas Z, Kozel FA, Large C, Cohn J, Bohning DE: Lamotrigine Increases The TMS Motor Threshold And, Using Interleaved TMS/fMRI, Inhibits The BOLD Response To TMS Over Motor And Prefrontal Cortex. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Dec. 9, 2001, Waikoloa,Hawaii.

 

207.     George MS, Rush AJ, Sackeim HA, Marangell LB, Nahas Z, Husain MM, Lisanby SH, Martinez JM: Vagus Nerve Stimulation (Vns) Continues To Show Therapeutic Benefit For Chronic Or Recurrent Treatment Resistant Depression Up To Two Years After Implant. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Dec. 9, 2001, Waikoloa,Hawaii.

208.     George MS, Nahasz, Li X, Chae JH, Kozel FA: The Role of rTMS in Treatment Resistant Depression. In a Panel: Treatment Resistant Depression: The Role of Innovative Treatments. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Dec. 10, 2001, Waikoloa,Hawaii.

 

209.     Upadhyaya VH, Brady KT, Lorberbaum JP, Back S, George MS: Using BOLD fMRI And A Public Speaking Task In Patients With Social Phobia And Alcoholism To Understand How Alcohol Affects Social Anxiety Circuits - A Pilot Study. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Dec. 10, 2001, Waikoloa,Hawaii.

 

210.     Nahas Z, Chae JH, Lomarev M, Denslow S, Anderson B, Kapp RM, Bohning DE, George MS: Serial Interleaved Vagus Nerve Stimulation (VNS) And Functional MRI In Treatment Resistant Depression Patients Enrolled In A Double-Blind Placebo Controlled VNS Study. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Dec. 10, 2001, Waikoloa,Hawaii.

 

211.     Lorberbaum JP, Newman JD, Horwitz AR, Dubno JR, Lydiard RB, Hamner MB, Bohning DE, George MS: The Functional Neuroanatomy of Human Maternal Behavior. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Dec. 12, 2001, Waikoloa,Hawaii.

 

212.     Chae JH, Lomarev M, Denslow S, Nahas Z, Min SK, George MS, Bohning DE: Vagus Nerve Stimulation (VNS) Synchronized BOLD fMRI Suggests That VNS In Depressed Adults Has Frequency And/Or Dose Dependent Effects At Rest And During A Simple Task. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Dec. 12, 2001, Waikoloa,Hawaii.

 

213.     Denslow S, Bohning DE, Lomarev MP, George MS: BOLD Activation in Motor Cortex Induced by TMS and Volitional Movement: Repeatability and Comparison of Location Assessed by Interleaved TMS/fMRI. International Society for Magnetic Resonance in Medicine (ISMRM).

 

214.     George MS, Nahas Z, Li X, Chae JH, Lomarev M, Bohning DE: Multimodality Imaging and Novel Treatments for Mood Disorders. Biol Psyhciatry 2002; 51:8S #23.

 

215.     Conway CR, Chibnall JT, Fletcher J, Li X, George MS: Changes in Brain Metabolism in Response to Long-Term Vagus Nerve Stimulation (VNS) for Depression and Relationship to Clinical Response. Biol Psychiatry 2002; 51:8S #126.

 

216.     Najib A, Lorberbaum JP, Kose S, Nahas Z, Bohning DE, George MS: Regional Brain Activity in Women Grieving A Romantic Relationship Breakup. Biol Psychiatry 2002; 51:8S # 254.

 

217.     Kozel FA, Revell LJ, Lorberbaum JP, Shastri A, Smith A, Nahas Z, Nadeau B, Bohning DE, George MS: Regional Brain Correlates of Electrodermal Activity: A Pilot fMRI Study  in Healthy Young Men. Biol Psychiatry 2002; 51:8S # 255.

 

218.     Li X, Tang J, Wu Z, Zhao G, George MS, Lui C: Cerebral Hypoperfusion and Laterality and Psychopathology in Chinese Patients with Schizophrenia. Biol Psychiatry 2002; 51:8S # 343.

 

219.     Nahas Z, Chae JH, Lomarev M, Denslow S, Anderson B, Kapp R, Bohning DE, George MS: Vagus Nerve Stimulation and fMRI in Treatment-Resistent Depression. Biol Psychiatry 2002; 51:8S #448.

 

220.     Conway CR, Chibnall JT, Fletcher J, Li X, George MS: Changes in Regional Cerebral Blood Flow in Response to Acute Vagus Nerve Stimulation (VNS) in Depressed Patients and Prediction of Clinical Response. Biol Psychiatry 2002; 51:8S #544.

 

221.     Li X, Teneback CC, Nahas Z, Kozel FA, Large C, Cohn J, Bohning DE, George MS: Lamotrigine Inhibits the Functional Magnetic Resonance Imaging Response to Transcranial Magnetic Stimulation in Healthy Adults. Biol Psychiatry 2002; 51:8S #567.

 

GRANT FUNDING:

 

FUNDED GRANTS (Past)

 

MUSC and UK Fellowship -Ciba-Geigy Grant, $5,000; Solvay-Duphar Grant $1,000; MUSC Resident Grant $2,000.

 

NIMH Intramural Grant Funding - 4 years of full-time support within the NIMH, DIRP, Bethesda, MD. Principal investigator on numerous projects involving mood disorders and emotion regulation using cerebrospinal fluid, brain imaging and transcranial magnetic stimulation.

 

Co-investigator (5% - 5,000/year) - Pergolide in Children with Tourette's Syndrome, F.R. Sallee PI. $428,336/ 3 years. Funded through the FDA, Orphan Drug Grant. Funded to begin 7/95.

 

Co-investigator - Limbic Sensitivity in Cocaine Addiction, Bryon Adinoff, PI.  $274,738, R21 National Institute on Drug Abuse (NIDA) Funding began 11/95.

 

Co-investigator - Phase II, Eight-week, Double-blind, Placebo-controlled Pilot Study Evaluating the Toleration, Safety and Efficacy of Oral Ziprasidone (Cp-88,059-1) in Children and Adolescents with Tourette's Syndrome. Pfizer Pharmaceuticals. Floyd R. Sallee, PI. Start Date 5/96.

 

Principal Investigator - MR Spectroscopy measurements of NAA and MI in Probable Alzheimer's Disease Patients Before and After Treatment with Milameline or Placebo. Small Grant ($24,000) Parke-Davis.

 

Consultant - The Patrick and Catherine Weldon Donaghue Medical Research Foundation - Connecticut, - Dennis Charney,MD and Nash Boutros, MD co-principal investigators. Transcranial Magnetic Stimulation and Treatment

of Depression.

 

Co-investigator - Parke-Davis protocol #979-15 A 52 week, randomized, double-blind, placebo-controlled, multicenter study of milameline in patients with probable Alzheimer's disease with extended open label treatment. J. Mintzer, MD MUSC PI. Start 7/96.

 

Principal Investigator - ($60,000 over two years) - A Dose Finding Study of Left Prefrontal Rapid Transcranial Magnetic Stimulation (rTMS) to Treat Depression'. 1996 NARSAD Young Investigator Award. Start Date 6/96.

 

Principal Investigator (10% salary for 2 years) Serial fMRI Perfusion Scans in Rapid-cycling Bipolar Affective Disorder Subjects: A pilot study using a novel non-invasive tool to longitudinally examine regional brain activity changes as a function of mood and disease progression. ($150,000 over two years).Stanley Foundation 1996 Research Awards. Start Date 7/96.

 

Principal Investigator - Neurolite SPECT Imaging of rCBF as a Predictor of Response to Antidepressant Activity (Transcranial Magnetic Stimulation). ($60,000 of radiotracer) Dupont Pharma. CG #96028 1997-99.

 

Principal Investigator (M. George) Neotonus : A Multi-Site Clinical Trial of rTMS in the Treatment of Unipolar Depression 4/98-4/99            5% Effort  $80,000

 

Principal Investigator - Fast MRI Brain Scanning in Alcoholism, $25,000/year x 4 years - $75,000, part of a $1.7 million NIAAA Center Grant, James C. Ballenger, PI, Raymond F. Anton, and Carrie Randall, Coordinators. 2/95 - 2/99.

 

Principal Investigator - Volumetric and functional MRI scanning in    schizophrenia patients before and after treatment with risperidone. Janssen Pharmaceutica. ($58,750) 8/96 - 8/99.

 

Principal investigator - Volumetric and Functional (Perfusion) MRI scanning in schizophrenia patients before, during and after treatment with Olanzepine:Using Imaging to Document Speed of Response. Eli Lilly $46,000 direct costs (Funded 4/97).

 

Principal Investigator (M George, PI) NARSAD Independent Investigator Award. Combining TMS with Echoplanar BOLD fMRI to Determine Optimum Treatment Parameters for Depression. 9/89-9/00. $100,000.

 

Co-investigator - NARSAD (M. Beale, PI)  rTMS Following a Single ECT: Antidepressant and Cognitive Effects 6/98 - 5/00 5% Effort $60,000.                         

 

Co-investigator - MUSC Foundation for Research Development - IDEAS Grant (D. Bohning, PI) Phased-Solenoid Array Coil for Deep Focused Transcranial Stimulation. 1997-78 - $30,000. 

 

Principal Investigator - Prefrontal Transcranial Magnetic Stimulation for the Treatment of Depression in Bipolar Affective Disorder: A Pilot Study of Acute Efficacy and Preventive Maintenance. ($150,000 over two years).Stanley Foundation 1998 Research Awards. Start Date 10/98.

 

Co-investigator (Mark Hamner, PI) VA Merit Neuroimaging in PTSD: Using IV Procaine and SPECT to Investigate Limbic Function 7/98 - 7/00 10% Effort $120, 000 annual         

 

Co-investigator - Non-neuroleptic treatments of childhood Tourette's Syndrome. F.R. Sallee, PI. NIMH RO1 (10% salary over 5 years). (Funded  3/97).  $1,385,000 over 5 years.

 

Co-investigator - RO1 DA11434-01A1 Limbic Sensitivity in Cocaine Addiction Bryon Adinoff, MD PI. NIDA, Funded 2/6/97 3 years $250,000/year. 20% effort. (M. George PI of Subcontract - 11,000/year).           

 

Principal Investigator -Using Interleaved Transcranial Magnetic Stimulation (TMS) BOLD fMRI to measure cortical excitability and MRS glutamate over motor and prefrontal cortex in normal volunteers before and during treatment with lamotrigine.  Glaxo/SmithKline - $146,000 (5/01-10/03).

 

Principal Investigator - Defense Related Applications of Transcranial Magnetic Stimulation (TMS):

Current Knowledge and a Focused, Applied Pilot Study – Defense Advanced Research Projects Agency (DARPA) - $300,000 (6/01 – 6/02).

 

Principal Investigator (M. George, PI) Cyberonics, Inc. DO1 - A Study of Vagus Nerve Stimulation in Patients with Depression: A Pilot and Efficacy Study  5/98-5/99 10% Effort  $240,000

 

Principal Investigator - The Functional Neuroanatomy of Borderline Pesonality Disorder: integrated fMRI and TMS studies testing dysfunctional circuits and developing a new treatment ($450,000 over 3 years). Swiss Foundation for Research in Personality Disorders. 1/00-1/03.

 

Co-Principal Investigator (With DE Bohning, PhD) - Vagal Nerve Stimulation Synchronized fMRI - VNS/fMRI (Cyberonics), $100,000 over one year (3/00-3/01).

 

Co-Principal Investigator (With DEB),Vagal Nerve Stimulation Synchronized fMRI - VNS/fMRI (Charles A. Dana Foundation for the Neurosciences). $100,000 total (2 years).

 

Co-investigator - Using Left Prefrontal TMS to Treat Schizophrenia Patients with Comorbid Major Depression.  (Z. Nahas PI). Neotonus. Start 1/00 - $60,000 over two years.

 

Co-Principal investigator - Volumetric and functional MRI scanning in depression,social phobia and obsessive-compulsive disorder before and after treatment with fluvoxamine. Solvay-Duphar, $20,000 (Funded 4/97).

 

Co-Investigator - Methodology for Interleaved TMS and fMRI. Daryl E. Bohning, PhD, PI. NIMH R21. $212,681 Direct Costs over 3 years. Start 6/99. 5% effort.

 

Consultant - Swiss National Scientific Research Grants - T. Schlaepfer, MD, PI. Effect of Rapid Transcranial Magnetic Stimulation on Refractory Major Depression. Submitted 9/95, funding to begin 6/96. 7 years duration. 

 

FUNDED GRANTS (Current)

 

Principal Investigator -  Phase 1: An Initial Efficacy Test and Determination of the Optimum Dose of a New AMPAkine Compound, CX516, on Measures of Sleepiness and Performance in Sleep-Deprived Adult Volunteers. Phase II: A Test for Replication, Coupled with BOLD fMRI to Determine the Regional Brain Activity Changes that CX516 Produces While Improving Sleep-Deprived Performance . Defense Advanced Research Projects Agency (DARPA) - $275,000 over 1 year (start 4/03).

 

Principal Investigator – Creating a Man-Portable TMS System to Improve War-fighter Performance. Defense Advanced Research Projects Agency (DARPA)  - $6,700,000 over 5 years. (Start 6/02).

 

Principal Investigator - NIH, NINDS, RO1- AG40956 Mood Effects of Deep Brain Stimulation in Parkinson’s Disease: A Combined DBS and MRI Study. $1,441,050 over three years. 10% Effort (Funding starts 12/00).

 

Principal Investigator - A Long-Term, Prospective, Multicenter Study to Compare the Clinical, Quality of Life, Health Care Utilization and Productivity Outcomes of the NeuroCybernetic Prosthesis (NCP®) System to Standard-of-Care Treatment in Patients with Depression.  Cyberonics, Inc.- $52,000 (Start 1/01).

 

Principal Investigator - A Multicenter, Pivotal, Safety and Efficacy Study of Vagal Nerve Stimulation Delivered by the  NeuroCybernetic Prosthesis (NCP®) System in Patients with Treatment Resistant  Depression (Cyberonics, inc). $407, 000 over three years (Start 8/00).

 

Principal Investigator - A Safety and Efficacy Multi-site Study of Vagus Nerve Stimulation (VNS™)  using the NeuroCybernetic Prosthesis (NCP®) System in Patients with Refractory Anxiety Disorders ($300,000 over three years)(start 11/00).

 

Co-Principal Investigator – (With Prof. Gordon Baylis, USC, Columbia), Using Functional Magnetic

Resonance Imaging (MRI) and Evoked Potentials (EP) to Understand Dysfunctional Attentional Networks in Young Adults with Attention Deficit Disorder. (MUSC, $50,000/year over three years. Sponsor: SC Research Collaboration (Start 6/02).

 

Co-Investigator - Using fMRI to Develop New Treatments for Alcoholism, $100,000/year x 4 years, part of a $1.7 million/year NIAAA Center Grant Renewal, James C. Ballenger, PI, Raymond F. Anton, and Carrie Randall, Coordinators. 1/01-1/04.

 

Co-Investigator - (Z Nahas, PI) Prefrontal rTMS For Negative Symptoms Of Schizophrenia ($350,000 over three years:  NIMH) start 1/03.

 

Consultant - Transcranial Magnetic Stimulation Treatment of Depression - David Avery, PI - R01, NIMH, $1,008,696 over three years (funded 2/00).

 

Co-investigator/mentor - An fMRI Study of Healthy Mothers Hearing Infant Cries. - J Lorberbaum, PI. R01, NIH, $459,632 over 3 years. 5%Effort. (Start 10/00).

 

Mentor - Hugh Myrick, PI - Training in Functional Imaging and Alcohol Withdrawal. NIAAA (K award) starts 7/00, $695,250 over 5 years (Start 7/00).

 

Mentor - Jeff Lorberbaum, MD - VA National Award for Research Training in PTSD (Start 6/00, three years).

 

Mentor – F. Andrew Kozel, MD - VA National Award for Research Training in PTSD (Start 6/01, three years).

 

Co-I (L.Key, PI).- Clinical Research Curriculum Award (CRCA) (to provide a broad-based, multidisciplinary, clinical research training program at the Medical University of South Carolina (MUSC)), NIH - $300,000.

 

 Co-investigator - Functional Imaging of the Human Brain in Health and Disease: Clinical and Research Applications.  Academic Equipment Grant, Sun Microsystems. D.J. Vincent, PI. $155,700 (Start 5/01).

 

 

GRANT FUNDING: Grants Submitted and Under Review

 

Director, Imaging Core, SC Alzheimer’s Disease Research Center. NIH, NIA.

 

Mentor (Kozel, PI) – Investigating the Neurocircuitry of Geriatric Depression. NIMH K23. $880,932 over 5 years (Submitted 6/1/03).

 

Mentor (Nahaz, PI) – Training in Deep Brain Stimulation (DBS) and Rodent Antidepressant-Screen Models. NIMH K08. $814,431 over 5 years (Submitted 6/1/03).

 

Co-Investigator (Bohning, PI) –3.0T Evolution of Interleaved TMS/fMRI Methodology  NIBIB, $2,163,832 over 5 years (Submitted 3/25/03).

 

Co-investigator (Cameron, PI) – Near Real-Time Processing of fMRI Data. NIH, NIBIB, $3,565,677 over 5 years (Submitted 3/25/03).

 

Overall Study Chairman and PI – Optimization of TMS for Depression: Coordinating Center Grant. NIMH 1.6 million over 5 years (Submitted 2/03).

 

Co-Investigator  (Nahas Z, local PI)- Optimization of TMS for Depression:  MUSC Clinical Site Grant NIMH 1.25 million over 5 years (Submitted 2/03).

 

MUSC PI and Overall Co-Investigator – (James Leckman, MD, PI, Yale) NIMH Conte Center Application. The Neural Origins of Tics, Habits and Stereotypies. NIMH Conte Center 15% effort, $1,265,000 over 5 years.

 

Co-Investigator – (Chris Rorden, PhD, PI, University of Nottingham) Synergistic Techniques for Imaging Stroke: Perfusion, Functional, Diffusion Tensor and Conventional MRI. 5% effort, NINDS. $439,620 over 4 years.

 

Principal Investigator – A Randomized Multi-Center Study of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Refractory Depression Compared to A Sham Treatment. NeuroNetics, LLC.

 

Co-investigator – (D. Roberts, PI) Human Cerebral Cortex Plasticity in Response to Long-Term Microgravity Exposure.  NASA Space Life Sciences - $342,310 over 2 years (submitted 9/01).

 

Principal-Investigator (Site) – Investigation of the neural network plasticity underlying action observation using single and paired pulse transcranial magnetic stimulation (TMS), repetitive TMS and functional MRI. International, multisite collaboration. $1,600,000 DM over 3 years: Volkswagen  (submitted 6/01).

Mentor (D. Roberts, PI) – MUSC Intramural Grants - Human Cerebral Cortex Plasticity in Response to Lower Limb Immobilization (Submitted 8/01).

 

Co-investigator. DR Roberts, MD (PI). Sponsor:  National Aeronautics and Space Administration (NASA)

Title: Human Cerebral Cortex Plasticity in Response to Microgravity Exposure 4 % effort  Period: April 1, 2002 – May 30, 2004 Direct Costs:  235,706 (Submitted 8/02)         

 

Co-investigator and Imaging Core Director– R. Booze, PhD (USC) overall PI. NIH-NCRR. The SC Center of Biomedical Research Excellence in Neurodevelopmental Disorders. 5 years, Direct Costs: 554,779 (Submitted 2/03).

 

 

 

 

 Patents and Invention Disclosures:

 

1) MR-Guided/MR-Compatible Pneumo-Mechanical TMS Coil Positioner TMS – with Daryl Bohning, PhD, Invention Disclosure, Filed  5/17/02. US Provisional Patent # 60/381,411.

 

2) System and Method of Using Synchronized Vagus Nerve Stimulation and funtional MRI to Determine the Optimum Individual Settings of VNS as Therapy. with Daryl Bohning, PhD and Ziad Nahas, MD. Filed 5/3/02. US Provisional Patent # 60/377,692

 

3) System and Method of Detecting Deception by fMRI. With F. A. Kozel, MD. Invention Disclosure filed 12/20/01. Provisional Patent # 60/341,137.

 

4) Methods and System of Using Transcranial Magnetic Stimulation to Enhance Cognitive Performance. With Daryl E. Bohning, PhD. Invention Disclosure filed 3/25/02. #19113.0093U1, provisional 60/367,520.

 

5) System and Method of Inhibiting the Ability to Decieve Using Functional Magnetic Resonance Imaging- guided TMS. With F.A. Kozel. Invention Disclosure filed 12/02/01.  Provisional 60/381,411.

 

6) Method and System of Using Interleaved TMS and fMRI to Assess the Regional Brain Effects of CNS active Compounds. With Daryl Bohning and Ziad Nahas. Filed 7/02.

 

 

Book and Chapter Reviews, published commentary:

 

Animal models of depression by Koob GF, Ehlers CL, Kupfer DJ (eds). Neurology 1990.

 

Emotions and the dual brain by Gainotti G, Caltagirone C (eds.) Neurology 1990:40,10:1640.

 

The triune brain in evolution: Role in paleocerebral functions, by Maclean, PD. Neuropsychiatry, Neuropsychology and Behavioral Neurology 1992:5,1:68-69.

 

Brainstem mechanisms of behavior by  Klemm, Robert P. Vertes (eds.). Neuropsychiatry, Neuropsychology and Behavioral Neurology 1992:5,1:67-68.

 

Delirium: Acute confusional states by Lipowski ZJ. Neurology 1991;41:614.

 

Current and future trends in anticonvulsant, anxiety and stroke therapy by Meldrum BS and Williams M (eds). Neuropsychiatry, Neuropsychology and Behavioral Neurology 1992:5,1: 72-73.

 

Lateral Asymmetries and Hemispheric Specialization by Anke Bouma. Neurology 1991.

 

Foundations of the Neuron Doctrine by Gordon M. Shepherd. Neurology 1992; 42:1258-59.

           

            Anxiety in the Elderly: Treatment and Research by Carl Salzman, Barry D.        Lebowitz (eds). American          Journal of Psychiatry 1993; 150:1264.

           

            Biological Psychiatry (Vols 1 and 2) by G. Racagni, N. Brunello, T. Fukuda (eds). American Journal of Psychiatry 1993; 150:1558.

 

            Hypnosis in the Treatment of Depressions: Strategies for Change by Michael Yapko. Neurology       1993;43:1275.

 

            Aging and Neuropsychological Assessment by Asenath La Rue. Neurology 1993;43:1868.

           

            Psychological Aspects of Depression by I.H. Gotlib, C.L. Hammen. American Journal of Psychiatry    1994;151:140.

 

            Brain Activation by Per E. Roland. American Journal of Psychiatry 1994; 151:1515.

           

            Neurobiology of Cingulate Cortex and Limbic Thalamus by B.A. Vogt, M. Gabriel (eds). Neurology 1994;        44:2425-2526.

 

            Feminist Perspectives on Eating Disorders by P. Fallon. J Nervous and Mental Disease 1955; 183, 4:   275-276.

 

            Seminars in Basic Neurosciences by G. Morgan, S. Butler (eds). American Journal of Psychiatry 1995;             152,4:          639-640.

           

            The Neurology of Thinking by D. Frank Benson. Neurology 1995; 45: 1244.

 

            Textbook of Geriatric Neuropsychiatry by C.E.Coffey, J Cummings (eds). American Journal of Psychiatry       1996; 153, 435.

 

            "Evidence & Experience in Psychiatry" Volume 4, Chapter 5: OCD Spectrum. By Eric Hollander, M.D.,             Jennifer Rosen, B.S. World Psychiatric Association, 2000

 

Functional MRI: An Introduction to Methods. Eds Peter Jezzard, Paul N. Matthews, Stephen M. Smith, Oxford Medical Publications, 2002. Published in Radiology, 2002. …

 

Invited and Named Lectures, Visiting Professorships:

 

May, 1998 - Pfizer Visiting Professorship Award - UC Davis

 

Plenary Speaker, 4th International Conference on OCD, St. Thomas, VI, Feb, 2000. “Research and Clinical Adances in Brain Stimulation Techniques”.

 

Plenary Session, Annual Meeting of the Chinese Medical Association, Taipai, Taiwan, June, 2001: “Minimally Invasive Brain Stimulation.”

 

Guest Speaker, Human Systems Conference 2001, Exploring the Human Frontier. The International Conference on Technologies for Human Factors and Psycho-Social Adaptation in Space and Terrestrial Applications. June, 2001, Houston, TX. “Transcranial Magnetic Stimulation as a Treatment for Depression and Potential Tool on Long-Range Missions”

 

12th Annual Samuel Guze Memorial Lecture, Washington Univeristy (St.Louis) Psychiatry Department, November 6, 2001

 

Visiting Professor, University of Groningen, Holland (July, 2001)– Department of Biological Psychiatry. Gave several lectures on gender differences in brain activity with respect to emotion, as well as lectures on TMS and VNS.

 

Plenary Lecture, Annual Danish Psychiatric Association Meeting, March 2, 2003.

 

Keynote Address, 36th Annual Meeting of the Royal Australian and New Zealand College of Psychiatrists (RANZCP), Hobart, Australia, May 17, 2003 – Title: Tickling the Brain: An overview of new technologies for treating depression.

AWARDS, ACTIVITIES AND HONORS:

 

High School:

 

Eagle Scout, Newspaper co-editor, soccer and cross-country team captain, president of the high school Honor Society, treasurer of the S.C. chapter of the National Honor Society, Boys State delegate.

 

College:

 

            Charles Dana and Joseph McConnell Honor Scholar

            National Honor Society Scholarship Recipient

            Member, Debate Team

            Member, Newspaper Staff

            Cum Laude graduate

 

Internship and Residency:

            Teaching

            Nominated, 1986 MUSC Golden Apple Award.

            Recipient, 1987 House Officers Excellence Award.

            Recipient, 1988-89 Psychiatry Golden Apple Award.

            Recipient, 1989 Association For Academic Psychiatry/Mead Johnson Fellowship in Academic Psychiatry.

 

            Administration                                       

            Neurology representative, MUSC Executive Housestaff Committee, 1988-89.

            Housestaff representative, MUSC Risk Management Committee, 1988-89.       

            Chief Resident, Neurology, 1989-90.                       

Recipient, 1989-90 American Medical Association/Burroughs Wellcome Leadership Program for Resident Physicians.

S.C. Delegate, Interim Meeting, American Medical Association Resident Physician Section, Dec. 1-2, 1989.

            S.C. Delegate, Annual Meeting, American Medical Association Resident Physician Section, June 23-25,         1990.

 

            Academic

            Best Poster Presentation, American Association for the Study of Headache, 31st Annual Scientific Meeting,     June 16-19, 1989. "A Study of the Seasonal Variation of Migraine."

            1989 -  The Benjamin C. Riggs Award for Best Resident Paper.

            1989 -  The Upjohn Young Investigators Award.

            1990 -  The Benjamin C. Riggs Award for Best Resident Paper.

 

 

Fellowship Training

 

            American College of Neuropsychopharmacology (ACNP)/Mead Johnson Travel Awardee, ACNP Annual     Meeting, San Juan Puerto Rico, December, 1992

 

            NIMH Award for Excellence in Clinical Care and Research, 1993

 

            American Neuropsychiatric Association Young Investigator Award, 1995

 

MUSC Faculty - Awards

 

            1996                    NARSAD Young Investigator Award

            1997                    Southern Association for Research in Psychiatry Outstanding Young Investigator Award

            1998                    Pfizer Visiting Professorship Award - UC Davis

            1998                    NARSAD Independent Investigator Award

            1998                   Finalist, Glasgow College International Neuropsychopharmacology (CINP) Young Scientist Award

            2000                    Member, SC Alpha Chapter of Alpha Omega Alpha (AOA), the National Honor Medical                                         Society

                                        Circle of Excellence Award for Outstanding Teaching in the Doctoring Curriculum I Course

                                        Honorable Mention, NARSAD Gerald Klerman Award for Clinical Research

            2003                    Circle of Excellence Award for Outstanding Teaching in the Doctoring Curriculum I Course

 

MUSC Faculty - Committees

 

            1999-2000          Member, Ad Hoc Committee to Integrate Research with the New MUH Hospital ‘Authority                        Status’

            1997-2000          Member, MUSC Institutional Review Board (IRB)

            1997-2000          Member, Ad Hoc Task Force on Feasibility of PET Imaging at MUSC

            1997-1998          Member, Search Committee for Neurology Chairman

            1999-2001          MUSC College of Medicine Faculty Senate

            1996-2001          Member, Undergraduate Medical School Curriculum Committee

            2000-2001          Member, Neuroscience Course Curriculum Change Committee--

            2001-2002          Chairman, MUSC Psychiatry Grand Rounds Committee

            2001-2002          Member, Radiology Department Chairman Search Committee

            2000-2002          Member, MUSC Pychiatry Department Management Team

 

            1998-present     Member, MUSC Institutional Review Board (IRB) 1

            2000-present     Faculty Advisor, Joint Neurology and Psychiatry Residency

            2001-present     Director, Specialty Division, MUSC Psychiatry

                         

 

HOBBIES:

 

            Sailing, windsurfing, hiking, golf, canoeing.     

 

MEMBERSHIPS, CIVIC ORGANIZATIONS:

 

            Sierra Club

            The National Wildlife Federation

            The Nature Conservancy

            Sunrise Presbyterian Church

            Participant, Renaissance Weekend, 1997, 1998, 1999

            Room Father - Miss Irene’s 3 year old class, O’Quinn School 2000-01