Curriculum Vitae

Transmissible Spongiform Encephalopathies Advisory Committee

Name:	Bernardino Ghetti
Citizenship:	------- ------------------------------------------
Date of Birth:	-----------------
Place of Birth:	--------------
Personal Data:	------------------------- ----------------------------- ---------------------
Home Address:	--------------------------- --------------------------------- --------------------------
Office Address:	Indiana University School of Medicine Department of Pathology and Laboratory Medicine Division of Neuropathology 635 Barnhill Drive A138 Indianapolis, Indiana 46202-5120 Telephone: (317) 274-7818 Facsimile: (317) 274-4882 Email: bghetti@iupui.edu
Present Academic Rank:	Distinguished Professor, March 1, 1997

Education

Liceo Classico "G. Galilei", Pisa, Italy ---------

Degree: Maturità Classica ----

University of Pisa Medical School, Pisa, Italy ----------

Institute of Anatomy, intern student 1959-1962
Institute of Medical Pathology, intern student 1962-1963
Institute of Psychiatry, intern student 1963-1966
Dissertation for Doctorate in Medicine (February 23, 1966) 1966

University of Pisa Medical School, Institute of Psychiatry and Institute of Mental and Nervous Diseases

Specialization in Mental and Nervous Diseases 1966-1969

University of Naples Medical School, Naples Italy

Department of Neurology, Postdoctoral Fellow in

Neuropathology (Visiting Fellow) 1968-1970

Albert Einstein College of Medicine, Yeshiva University, Bronx, N.Y.

Research Fellow, Department of Pathology (Neuropathology) 1970-1973

Albert Einstein College of Medicine and Bronx Municipal Hospital

Department of Pathology

Resident in Pathology 1973-1975
Resident in Neuropathology 1975-1976

Academic Appointments

University of Pisa Medical School, Pisa, Italy

Postdoctoral Fellow 1966-1970
Eligible for a position of Assistant Professor of Psychiatry 1970
(Bulletin of Italian Department of Education, April 30, 1970)

University of Naples, Naples, Italy

Postdoctoral Fellow & Visiting Fellow 1968-1970

Albert Einstein College of Medicine, Bronx, NY

Research Fellow, Department of Pathology (Neuropathology) 1970-1973
Instructor, Department of Pathology (Neuropathology) 1973
Clinical Fellow, Department of Pathology 1973-1975
Clinical Fellow, Department of Pathology (Neuropathology) 1975-1976

Indiana University School of Medicine, Indianapolis, IN

Assistant Professor of Pathology 1976-1977
Assistant Professor of Pathology and Psychiatry, 1977-1978
Associate Professor of Pathology and Psychiatry, 1978-1983
Associate Professor of Pathology, Graduate Faculty 1980-1983
Professor of Pathology and Psychiatry, 1983-1991
Professor of Pathology, Graduate Faculty 1983-present
Associate Director Graduate Program in Medical Neurobiology 1983-2000
Professor of Pathology, Psychiatry, Medical and Molecular Genetics 1991-1993
Professor of Pathology and Laboratory Medicine, Psychiatry Medical and Molecular Genetics 1993-present
Distinguished Professor of Pathology and Laboratory Medicine, Psychiatry, Medical and Molecular Genetics, and Neurology 1997-present
Chancellor’s Professor, Indiana University-Purdue University at Indianapolis

Administrative Positions

Indiana University School of Medicine, Indianapolis, IN

Director, Electron Microscopy Laboratory, Division of Neuropathology 1976-present
Associate Director Division of Neuropathology, Department of Pathology 1989-1993
Director, Indiana Alzheimer Disease Center (NIA) 1991-present
Leader, Administrative Core (IADC) 1991-present
Leader, Neuropathology Core (IADC) 1991-present
Director, Division of Neuropathology
Department of Pathology and Laboratory Medicine 1993-present
Leader, Neuropathology Core, Emory University Alzheimer Disease Research Center 2005-present

Hospital Appointments

Clarian Health Partners (IU, Methodist and Riley Hospitals)
Wishard Memorial Hospital
Veterans Administration Hospital
Clarian West Hospital
Clarian North Hospital

Consultanships

Consultant for Neuropathology of Aging and Degenerative Diseases: -------------- ----------------------------------------------------- 1980-present
Member of site visit team for the National Institute of Aging (NIA) 1984
Member of the Alzheimer Disease Research Center Ad Hoc Review Committee (NIA) 1984
Member of the Small Grant Review Ad Hoc Committee (NIA) 1984
Member of the Neurological Disorders Program Project Review B Committee (NINCDS) 1985-1989
Member of site visit team for the Neurological Disorders Program Project Review B Committee (NINCDS) 1985-1989
Consultant for the Indiana Federation of Alzheimer's Family Group 1986-1991
Ad Hoc Member of the Pathology A Study Section, PHS Division of Research Grants, NIH 1987
Consultant for the Arizona Disease Control Research Commission 1987
Member of the External Advisory Committee Alzheimer Research Center, University of Kentucky (Lexington) 1987-2001
Reviewer for the National Science Foundation 1988
Consultant for the Commonwealth of Virginia 1989, 1990
Member of the National Institutes of Health Reviewers Reserve 1989-1993
Ad Hoc Member of the Neurological Disorders Program Project Review B Committee (NINCDS) 1989
Member of Special Review Committee of the Neurological Disorders Program Project Review B Committee (NINCDS) 1990
Chairman of site visit team for the Neurological Disorders Program Project Review A Committee (NINCDS) 1990
Ad Hoc Member of the Neurological Disorders Program Project Review A Committee (NINCDS) 1990
Member of site visit team for the Neurological Disorders Program Project Review B Committee (NINCDS) 1991
Member of the NINDS/NIA Ad Hoc Review Committee on Alzheimer Disease 1991
Member of the International Scientific Advisory Committee Third International Conference on Alzheimer's Disease and Related Disorders 1991-1992
Member of the External Advisory Committee Alzheimer Research Center, New York University, New York, NY 1993-present
Member of the International Scientific Advisory Committee Fourth International Conference on Alzheimer's Disease and Related Disorders 1993-1994
Member of Site Visit Team National Institute of Aging (NIA) 1993
Member of Site Visit Team National Institute of Child Health and Human Development (NICHD); Mental Retardation Research Committee 1994
Chairman of site visit team for the National Institute on Aging 1994
Member of the International Scientific Advisory Committee Fifth International Conference on Alzheimer's Disease and Related Disorders 1995-1996
Member of Review Panel International Human Frontier Science Program - Research Grants 1997-present
Member of Review Panel, Medical Research Council, London, UK 1997-present
Member of the International Scientific Advisory Committee Sixth International Conference on Alzheimer's Disease and Related Disorders 1997-1998
Member of the Working Group on Medicine and Biotechnology (Brain and Behavior) of the World Federation of Scientists 1997-1998
Member of the Permanent Monitoring Panel on Transmissible Spongiform Encephalopathies and on Brain and Behavior of the World Federation of Scientists 1998-1999
Member of the Permanent Monitoring Panel on Medicine and Biotechnology of the World Federation of Scientists 1998-present
Chairman, Permanent Monitoring Panel on Brain and Behavior of the World Federation of Scientists 1999-present
Member of the Permanent Monitoring Panel on Transmissible Spongiform Encephalopathies 1999-present
Member of the Alzheimer Disease Research Scientific Review Committee, American Health Assistance Foundation (AHAF) 1998-present
Member of the Program Committee for the Seventh International Conference on Alzheimer's Disease and Related Disorders 1998-2000
Member of the Advisory Panel for Neurodegenerative Diseases, International Congress of Neuropathology 2000, Birmingham, UK 1999-2000
Member of the Special Emphasis Panel for Alzheimer Disease Core Center Application Review (NIA) 1999
Member of the Special Emphasis Panel for Alzheimer Disease Research Center Application Review (NIA) 1999
Member of the Site Visit Team (NIA) 1999
Member of the Scientific Advisory Committee for the Eighth International Conference on Alzheimer’s Disease and Related Disorders 2000-2002
Member of the Scientific Committee of the 7^th European Congress of Neuropathology, Neuropathology 2002 2001-2002
Member of the Program Committee of the International Congress of Neuropathology 2003 2001-2003
Member of the Scientific Advisory Committee for the Nineth International Conference on Alzheimer’s Disease and Related Disorders 2002-2004
Member of the National Cell Repository for Alzheimer’s Disease Advisory Committee (NIA) 2002-present
Member of the Medical Advisory Council for the Association for Frontotemporal Dementias 2003-present
Member of the Special Emphasis Panel for Alzheimer Disease Research Center Application Review (NIA) 2003
Member of the External Scientific Advisory Board of the Massachusetts Alzheimer's Disease Research Center 2004-2009
Member of the External Scientific Advisory Committee of the Johns Hopkins University Alzheimer's Disease Research Center 2004-2009
Member of the External Scientific Committee of BrainNet Europe 2004-present
Member of Transmissible Spongiform Encephalopathy Advisory Committee of the Food and Drug Administration 2006-present

Specialty Board Status

Specialist in Mental and Nervous Diseases (Italy) 1969
American Board of Pathology: Board Certification in Neuropathology 1982

Licensure

License to Practice Medicine, Italy 1966
Education Council for Foreign Medical Graduates (ECFMG) Examination, January 24, 1973, Certificate No. ------------
FLEX examination, December 7-9, 1976 1976
Medical Licensing Board of Indiana, February 10, 1977 License No. ----- 1977

Professional Societies

International Society of Neuropathology 1977 - Present
American Association of Neuropathologists 1977 - Present
Society for Neuroscience 1977 - Present
European Neuroscience Association
International Brain Research Organization 1977 - Present
Association for Research in Nervous and Mental Diseases Present
American Society for Cell Biology 1981 - Present
New York Academy of Science 1983 - Present
American Academy of Neurology 1991 - Present
World Federation of Neurology, Research Group on Dementia (Associate Member) 1990 - Present
Italian Society of Psychiatry 1966 - 1998
Italian Association of Neuropathology, Section of the Italian Society of Neurology 1969 - Present
British Brain Research Association 1977 - Present
European Brain and Behavior Society 1977 - Present
Indiana Neurological Association Present
World Federation of Scientists 1997 - Present
American Association for the Advancement of Science 1993 - Present
American Society for Neural Transplantation Present
American Neurological Association 2002 - Present

Offices

President, Indianapolis Chapter Society for Neuroscience 1981-1983
Member of the Program Committee of the American Association of Neuropathologists 1986-1989
Treasurer, Indianapolis Chapter Society for Neuroscience 1986-1990
Member of the Awards Committee American Association of Neuropathologists 1995-1996
Chairman of the International Congress Committee American Association of Neuropathologists 1995-1997
Councilor of the American Association of Neuropathologists to the International Society of Neuropathology 1995-2001
President Elect, American Association of Neuropathologists 1995-1996
Member of the Executive Council American Association of Neuropathologists 1995-2001
President of the American Association of Neuropathologists 1996-1997
Co-Director, National Prion Disease Pathology Surveillance Center Sponsored by the American Association of Neuropathologists 1996-present
Chairman of the Nominating Committee American Association of Neuropathologists 1997-1998
Member of the Executive Committee International Society of Neuropathology 1997-present
Member of the Nominating Committee American Association of Neuropathologists 1998-2001
Vice-President of the International Society of Neuropathology 2000-2003
President Elect, International Society of Neuropathology 2005-2006
President, International Society of Neuropathology 2006-2010
Member of the International Advisory Board, Neuropathology and Applied Neurobiology 2007-present

Honors

Silver Medal of the University of Pisa, for M.D. degree "cum laude" 1966
Specialization in Mental and Nervous Diseases "cum laude" 1969
Listed in: Who is Who in Frontier of Science and Technology 1984
Who is Who in the World 1984
Who is Who in the Midwest 1984
Personalities of the West and Midwest 1985
Personalities of America 1985
Who is Who in America 1986-present
Selected abstract for communication to Science Writers at the Annual Meeting by the Public Committee of the Society for Neuroscience 1986
Honorable Mention, Weil Award for best paper on experimental Neuropathology, 63^rd Annual Meeting of the American Association of Neuropathologists 1987
Invited neuroscientist at the meeting "Le Scienze Neurologiche Italiane nel mondo" Montedison Progetto Cultura Milano, Italy (November ) 1987
Silver Anniversary Medal of the University of Pisa 1990
Honorable Mention, Moore Award for best paper on clinicopathologic correlation, 67^th Annual Meeting of the American Association of Neuropathologists 1991
Kenneth M. Campione Visiting Professor of Neurology, Northwestern University Medical School, Chicago, IL Department of Neurology (November 12) 1991
Javits Neuroscience Investigator Award 1992-1999
Irwin Research Scholar, Indiana University-Purdue University 1995-1997
Moore Award for best paper on clinicopathologic correlation 71^st Annual Meeting of the American Association of Neuropathologists 1995
President Elect of the American Association of Neuropathologists, 1995-1996
Honorable Mention, Moore Award for best paper on clinicopathologic correlation 72^nd Annual Meeting of the American Association of Neuropathologists 1996
President of the American Association of Neuropathologists 1996-1997
Distinguished Professor of Pathology and Laboratory Medicine, Psychiatry, Medical and Molecular Genetics and Neurology, Indiana University School of Medicine 1997-present
Moore Award for best paper on clinicopathologic correlation 74^th Annual Meeting of the American Association of Neuropathologists 1998
American Academy of Neurology, Potamkin Prize Winner 1999
Honorable Mention, Weil Award for best paper on experimental neuropathology, 75^th Annual Meeting of the American Association of Neuropathologists 1999
Moore Award for best paper on clinicopathologic correlation 77^th Annual Meeting of the American Association of Neuropathologists 2001
Elected Active Member, American Neurological Association 2002
Honorable Mention, Weil Award for best paper on experimental Neuropathology, 78^th Annual Meeting of the American Association of Neuropathologists 2002
Award for Meritorious Contribution to Neuropathology, American Association of Neuropathologists 2003
Who is Who in Medicine and Healthcare 2004
Honorary doctorate in medicine, University of Siena, Italy 2005
“Saul R. Korey Lecture”, 81^st Annual Meeting of the AANP, Arlington, VA 2005
President of the International Society of Neuropathology 2006-2010
“Alfred Meyer Lecture”, Annual Meeting of the British Neuropathological Society, London 2007
Chancellor’s Professor, IUPUI 2007

Course Assignments In Present Rank

Course #C603, General Pathology for medical students, 195 enrolled.
Lecture: Neurobiology of Aging. Laboratory: gross and microscopic pathology; lst term (30 students) (40 hours).
Course #X601, Introduction to Medicine. Laboratory: gross and microscopic Pathology; 2^nd and 3^rd terms (30 students) (32 hours)
Course #C604, Systemic Pathology: Lectures and Laboratories in Neuropathology, 3^rd term (195 enrolled) (26 hours).
Course #X602, General Pathology for Medical Students. Lectures in Neuropathology. (Bloomington campus of I.U.) 2^nd term (25 students) (3 hours)
Course VMI 531, Human Pathology II Lectures in Neuropathology. (Purdue Campus of I.U.), Spring semester (12 students) (3 hours)
Course #93CA870, Electron Microscopy in Neuropathology;
Course #93CA880, Neurobiology and Neuropathology of Aging and Dementia;
Course #93CA890, Experimental Neuropathology. Senior elective courses. (Course Director)
Course #D505, Medical Neurobiology, 195 enrolled. 3 lectures, 3^rd term (3 hours).
Course #F724, Physiology of Nervous System, 15 enrolled. 3 lectures, Spring semester.
Course #N800, Research in Medical Neurobiology, 1 graduate student. 45 credit hours (Summer 1985-Spring 1987).
Chairman of the Advisory and Dissertation Research Committees supervising the graduate training of ---. ---------(Ph.D. candidate) 1986-1987.
Member of the Dissertation Research Committee supervising the graduate training of Ph.D. candidates: -- ------ 1988-90, ---------------- 1988-1993, --------------- 1988-1990, ------------ (Ph.D. candidates).
Chairman of the Dissertation Research Committees supervising the graduate training of ---------------. 1990-1993.
Chairman of the Advisory and Dissertation Research Committees supervising the graduate training of --------- 1990-1996, (M.S. candidate).

Clinical Teaching In Present Rank

Diagnostic ultrastructural studies of brain, nerve and skin biopsies (frequently with senior medical students and/or residents).
Checking out cases in the Division of Neuropathology (surgical specimens, brain, nerve and skin biopsies).
Participation in the training of Pathology, Psychiatry and Neurology residents and senior medical students.
Review the neuropathology in autopsies (with Pathology residents).
Lectures on neuropathology and experimental neuropathology for Neurology, Psychiatry, and Pathology residents.
Clinicopathological correlations in dementia, Indiana Alzheimer Disease Center (Faculty, fellows and residents).

Teaching In Postgraduate & Continuing Education Courses In Present Rank

Ball State University, Department of Nursing, January 1983
Ball State University, Department of Nursing, September 1983
Indiana University, Department of Continuing Education, April 1984
Purdue University, Department of Continuing Education, April 1984
Ball State University, Department of Continuing Education, October 1984
Indiana University, Division of Continuing Education, December 1993
College of American Pathologists, April 1998
American Academy of Neurology, April 2005

Attendance At Postgraduate & Continuing Education Courses In Present Rank

57^th, 58^th, 59^th, 60^th, 62^nd, 64^th, 65^th, 66^th, 67^th, 68^th, 69^th, 70^th, 71^st, 72^nd, 73^rd, 74^th, 75^th, 76^th, 77^th, 78^th, 79^th, 80^th , 81^st, and 82^nd annual meetings of the American Association of Neuropathologists, Inc., 1982 - 2004 for over 432 category I credit hrs.
22^nd Annual Meeting of the Frank B. Walsh Society 11 category-I credit hrs.
Meeting of College of American Pathologists, 1998, 3 category-I credit hrs.
VII National Alzheimer Disease Education Conference., 1998, 8 category-I credit hrs.
VIII International Symposium on Amyloidosis, 1998, 22.5 category-I credit hrs.
VII International Conference on Alzheimer Disease and Related Disorders, 2000
International Symposium on Neurodegeneration, 2001, 5.25 category-I credit hrs.
VIII International Conference on Alzheimer Disease and Related Disorders, 2002, 28 category 1 credits
7^th and 8^th International Congress of Parkinson’s Disease and Movement Disorders, 2002 & 2004, 34.5 category 1 credits.
55^th, 56^th, 57^th and 58^th annual meetings of the American Academy of Neurology, 2003 - 2006, 73.50 category 1 credits
129^th annual meeting of the American Neurological Association, 2004.
35^th annual meeting of the Society for Neuroscience, 2004.

Service

Indiana University-Purdue University at Indianapolis

Member of the Laboratory Animal Care and Use Committee 1989-1998
Representative to IUPUI Faculty Council 1995-1997
Member of the Glenn W. Irwin, Jr., Research Award Committee 1997-1999
Member of the Chancellor Professorship Committee 2001-2003, 2004

Indiana University School of Medicine

Member of the Biomedical Research Committee 1984-1989
Member of the Committee of the Student Research Program in Academic Medicine 1987-1989
Member of the Committee for the Future Development of the
Medical Science Program I.U. Bloomington 1988
Member of the Search and Screen Committee for the Chair of the Department of Anatomy 1988
Member of the Animal care subcommittee 1989-1994
Member of the Committee to establish a transgenic-mouse facility 1989-1994
Member of the Program Committee for the Second Biennial Medical School Scientific Session 1991
Member of the Pathology/LARC Veterinarian Search Committee, 1990-1991
Member of the Search and Screen Committee for the Chair of the Department of Neurology 1993
Member of the Committee of the Student Research Program in Academic Medicine 1995-1998
Member of the Research Goals Committee for Basic Research 1997
Member of the Search and Screen Committee for the Head and Librarian for Ruth Lilly Medical Library 1998-1999

Department of Pathology:

Chairman of the Research Committee 1977-1978
Member of the Electron Microscopy Committee 1977-1978
Chairman of the Seminar & Postgrad. Education Committee 1979-1985
Chairman of the Research Subcomm. of the Space Committee 1981
Member of the Safety Committee 1981-1982
Member of the Promotion and Tenure Committee 1983-1985, 1988-1990; 1999-2000; 2001-2002
Member of the Electron Microscopy Committee 1985
Member of the Research Committee 1985-1987
Member of the Search and Screen Committee for the Director of the Pediatric Pathology Division 1988
Chairman of the Search and Screen Committee for two Faculty positions for the Laboratory of Cellular and Molecular Neuropathology 1988-1990
Director, Division of Neuropathology, 1993-present
Member of the Research Committee 1995-1998
Member of the Seminar Committee 1995-1998
Member of the Executive Committee 1998-present
Member of the Compensation Committee 1998-2000
Member of the Research Committee 1999-present

Department of Psychiatry:

Member of the Medical Neurobiology Committee 1983-2000
Member of the Study Committee to review the program of the Institute of Psychiatric Research 1985
Member of the Research Committee 1987-1993

Student service:

Informal counseling

Community service:

Contact Neuropathologist for the Alzheimer's Association, formerly, Association for Alzheimer's and Related Diseases 1982-1991
Diagnostic service in Neuropathology to families

Membership of Editorial Boards and Editorial Activity
Previous Editorial Board Memberships:

Journal of Neural Transplantation 1990-1995
Journal of Neuropathology and Experimental Neurology, 1992-1995
Amyloid 1997-1999
The Italian Journal of Neurological Sciences, 1995-2002

Current Editorial Board Memberships:

Brain Research Bulletin 1996-present
Brain Pathology 2001-present
Neuropathology 2003-present
Current Alzheimer Research 2003-present
Neurodegenerative Diseases 2003-present

Referee Activity:

Brain Research (Guest Referee)
Journal of Neurobiology
Brain Research Bulletin
Neurobiology of Aging
Experimental Aging Research
Journal of Neurochemistry
Cell and Tissue Research
Journal of Neuropathology and Experimental Neurology
Laboratory Investigation
Proceedings of the National Academy of Science U.S.A.
Neurology
Journal of Neural Transplantation
Experimental Brain Research
Anatomy and Embryology
Trends in Neurosciences
Journal of the Neurological Sciences
Genomics
Nature Genetics
Science
Journal of Neuroscience
European Journal of Neuroscience
Nature Medicine
Annals of Neurology
Archives of Neurology
American Journal of Pathology
Experimental Neurology
Italian Journal of Neurological Sciences
Modern Pathology
Journal of Neurology
Molecular Brain Research
Journal of Histochemistry and Cytochemistry
Archives Italiennes de Biologie

Grants, Fellowships And Awards

Fellowship of the University of Pisa, June-Dec. 1966.
Fellowship of the Italian Department of Education, Jan.-Dec. 1968.
Fellowship of the University of Pisa, July 1968-June 1970.
Fellowship of the Italian National Council for Research, CNR, June 1970-May 1971.
Fellowship of the Italian National Council for Research, June-Dec. 1971.
Fellowship of the North Atlantic Treaty Organization (NATO) June 1972-May 1973.
Grant # PHS S01 RR 5371, Neuropathology: Degeneration and aging of the brain. Biomedical research support grant, for the period 7/1/76 to 6/30/77. ($6,000).P.I.
Grant # PHS R01 NS 04607 13. Title: Study of diffuse degenerative CNS diseases. USPHS Grant for the period January 1975 through December 31, 1977, (last two years of a 13-year project conceived by Dr. Wolfgang Zeman and his collaborators). Dr. Zeman left the University and the project in 1976; Dr. Ghetti replaced Dr. Zeman as Principal Investigator. ($45,000 per year).
Grant # PHS S07 RR 05371. Title: A model for aging and degenerative CNS diseases. Biomedical research support grant, for the period 9/1/77 to 11/30/79. ($7,900). P.I.
American Cancer IN-46R Grant. Title: Experimental maytansine encephalopathy. American Cancer Society Institutional grant, for the period 7/1/77 to 6/30/78. ($-----). P.I.
American Cancer IN-46S. Title: Neurocytologic changes induced by the antimitotic maytansinoids. American Cancer Society Institutional grant, for the period 7/1/78 to 6/30/79. ($-----). Faculty Sponsor.
American Cancer IN-46-T. Title: Cell pathology secondary to the (chemical or) pharmacological derangement of the regulatory mechanisms of the tubulin-microtubule system. American Cancer Society Institutional grant, for the period 7/1/79 to 6/30/80. ($-----). Faculty Sponsor.
Grant PHS R0l NS14426 (-01, -02, -03). Title: Selective neuronal loss and its sequelae: A model. For the period 12/1/79 to 11/30/82, extended to 11/30/83. ($110,109). P.I.
Biomedical Research Committee PDP-IU. Title: Chronic encephalomyelopathy with neurofibrillary degeneration in adult rabbits. For the period 3/1/82 to 2/28/83. ($------). P.I.
American Cancer Society IN-46-V. Title: Protection of neuronal microtubules against toxic effect of anti-tubulin agents by Lithium ions. American Cancer Society Institutional grant, for the period 7/1/81 to 6/30/82. ($----). Faculty Sponsor.
Grant PHS 1R03 AG04252-01. Title: Neuronal loss in experimental aluminum toxicity. For the period 8/1/83 to 7/31/84. ($15,000). P.I.
Grant NIMH-T32-MH17107. (Training Grant). Title: Neurobiological aspects of mental disorders. For the period 12/1/82 to 11/30/86. ($200,640). J. N. Hingtgen, P.I.
Grant PHS 2R01 NS14426 (-04, -05, -06). Title: Selective neuronal loss and its sequelae: A model. For the period 12/01/83 to 11/30/86 ($77,000/year). Extended to 6/30/1987 with an additional award of $15,000. P.I.
Grant PHS 1R03 AG05310-01. Title: Aluminum, neurotoxicity and gene expression. For the period 1/1/85 to 12/31/85. ($15,000). C. H. Lee, P.I.
Epilepsy Foundation of America. Title: Molecular mechanism of aluminum toxicity in relation to epilepsy. For the period 3/1/85 to 2/28/86. ($------). C. H. Lee, P.I.
Grant PHS 1R03 A#05563-001. Title: Role of amyloid proteins in Alzheimer's disease. For the period 4/1/85 to 3/31/86, extended to 11/30/86. ($15,000). P.I.
Eli Lilly and Company. Title: Effects of nerve growth factor on the survival of transplanted cerebellar nerve cells in mutant mice with neurodegenerative disorders. For the period 9/13/85 to 9/12/86. ($-----). P.I.
The Association for the Advancement of Mental Health Research and Education. Title: Relationship of genotype to number of substantia nigra neurons in weaver mutants. For the period 2/19/86 to 2/18/87. ($-----). P.I.
The Association for the Advancement of Mental Health Research and Education. Title: Sequence of developmental abnormalities leading to substantia nigra deficit in weaver mutant mice. For the period 6/1/86 to 5/31/87. ($-----). L. C. Triarhou, P.I.
Biomedical Research Committee Type II Grant. Title: Selective neuronal loss and its sequelae. For the period 12/1/86 to 11/30/87. ($-----). P.I.
The Association for the Advancement of Mental Health Research and Education. Title: Preliminary biochemical and molecular analyses of the cerebellum of pcd (Purkinje cell degeneration) mutant mice. For the period 12/1/86 to 9/1/87. ($-----). S. R. Dlouhy, P.I.
Grant PHS R01 NS 14426 (-07 through -011). Title: Selective neuronal loss and its sequelae: A model. For the period 7/1/87 to 6/30/92. ($130,000/year). P.I.
Fraternal Order of Eagles. Title: Alzheimer Research. For the period of 8/1/88 to 7/31/89. ($-----). P.I.
The Association for the Advancement of Mental Health Research and Education. Title: Molecular Genetics of Gerstmann-Sträussler-Scheinker Disease. For the period 8/1/88 to 7/30/89. ($-----). P.I.
The Association for the Advancement of Mental Health Research and Education. Title: Construction of cDNA libraries in normal and Purkinje cell degeneration mutant mice. For the period 9/1/89 to 8/31/90. ($-----). K. Graber, P.I.
Eli Lilly and Company. Title: Neurobiology of the weaver mutant mouse. For the period 10/1/89 to 9/30/90. ($------). P.I.
Biomedical Research Committee Type II Grant. Title: Molecular biology of granule cells in weaver mutant mice. For the period 10/1/89 to 9/30/90. ($------). M. E. Hodes, P.I.
The Association for the Advancement of Mental Health Research and Education. Title: The development of substantia nigra cells from weaver mutant mice. For the period 6/1/90 to 7/1/90. ($-----). C. Hingtgen, P.I.
Biomedical Research Committee Type II Grant. Title: Neurobiology of the Weaver mutant mouse. For the period 8/1/90 to 11/30/90. ($-----). P.I.
Biomedical Research Committee Type II Grant. Title: Genetic studies of a unique syndrome of ataxia, presenile dementia and Parkinsonian signs. For the period 11/1/90 to 10/31/91. ($------). S. R. Dlouhy, P.I.
Program Project Grant 1 P01 NS 276131. Title: Neurobiology of the Weaver Mutant Mouse. For the period 1/1/91 to 12/31/95. ($-------/year). P.I.
American Health Assistance Foundation. Title: PrP Amyloidosis with Alzheimer changes. For the period 4/1/91 to 3/31/92. ($------). P.I.
Grant PHS R01 AG09956. Title: "The Dementias: Indianapolis-Ibadan comparative prevalence". For the period 7/1/91 to 6/30/95. ($682,513/year). H. H. Hendrie, P.I.
Grant PHS R01 NS 29822 (-01 through -03). Title: "Biology of Hereditary PrP Amyloidosis with Tangles". For the period 7/1/91 to 11/30/94. ($411,550/year). P.I.
Grant 1 P30 AG 10133 (-01 through -03). Title: Indiana Alzheimer Disease Core Center. For the period 9/30/91 to 6/30/93. ($-------/year). P.I.
Grant 1 P30 AG 10133 (-03 through -05). Title: Indiana Alzheimer Disease Core Center. For the period 9/30/93 to 6/30/96. ($---------/year). P.I.
Alzheimer's Association PRG-91-158. Title: "Hereditary dominant dementias with amyloid plaques and neurofibrillary tangles. For the period 12/1/91 to 11/30/92. ($------/year). P.I.
Alzheimer's Association PRG-91-159. Title: "Amyloid precursor protein (APP) and Alzheimer's disease". For the period 12/1/91 to 11/30/92. ($------/year). M. D. Benson, P.I.
Grant PHS R01 AG10608. Title: "Amyloid precursor protein (APP) and Alzheimer's disease". For the period 7/1/92 to 6/30/95. ($198,589/year). M. D. Benson, P.I.
Grant PHS R01 AG 10297. Title: "ß-Amyloid gene promoter". For the period 5/01/92 to 4/30/95. ($95,187/year). D. K. Lahiri, P.I.;
Grant PHS R01 NS 14426 (-12 through -18). Title: Selective neuronal loss and its sequelae: A model. For the period 7/1/92 to 6/30/99. ($380,000/year). P.I. (Extended to 6/30/02 with no additional funds.)
Grant PHS R01 NS 29822 (-04 through -06). Title: "Biology of Hereditary PrP Amyloidosis with Tangles". For the period 12/1/94 to 11/30/97. ($560,591/year). P.I.
Irwin Research Scholarship, Indiana University-Purdue University. For the period 7/1/95 to 6/30/97. ($------).
Moore Award for best paper on clinicopathologic correlation, 71^st Annual Meeting of the American Association of Neuropathologists, 1995. ($---)
Grant 2 P30 AG 10133 (-06 through -10). Title: Indiana Alzheimer Disease Core Center. For the period 7/1/96 to 6/30/01. ($ ---------/year). P.I.
Eli Lilly and Company. Title: Characterization of the PDAPP X APOE (Knockout) Strain of Mice (PDApoE) For the period 12/01/96 to 11/30/97. ($-------). P.I.
Grant NIH. Title: "Biology of chromosome 17-linked dementia with tauopathy". For the period 4/1/98 to 3/31/01. ($304,208/year). P.I.: J. Murrell
Alzheimer Association (Temple Award). Title: Effect of ApoE and TTR genes on amyloid ß deposition and amyloidogenesis. For the period 1/1/98 to 12/31/99. ($-------/year). P.I. (Extended to 12/31/01 with no additional funds.)
American Health Assistance Foundation. Title: “Transgenic Mice Expressing a Prion Protein with an Insertional Mutation”. For the period 4/1/00 to 3/31/02. Co-P.I., P.I. D. Harris
Grant 1 R01 NS40975 (01 through 05). Title: “Murine Transgenic Models of Prion Diseases. For the period 1/15/01 to 11/30/05. Subcontract $------/year. P.I. of subcontract, P.I. D. Harris
Grant NIH PHS R01 NS 40314 (years 1-5) Title: IGF-I Therapy for Hereditary Cerebellar Ataxia. For the period 4/1/01 to 03/31/06 ($362,063/year). P.I. Wei-hua Lee.
Grant NIH PHS P30 AG 10133 (years 11-15) Title: Indiana Alzheimer Disease Center. For the period 7/1/01 to 6/30/06 ($1,545,854/year). P.I.
Grant NIH U01 AG 16976 Title: Atypical Dementia: From Neuropathology to Molecular Etiology. Supplement to the IADC 7/1/00 to 6/30/02. Principal Investigator. $92,500 /year.
Grant NIH U24 AG21886-01S1 National Cell Repository for Alzheimer’s Disease. For the Period 07/01/01 to 06/30/06. P.I. Tatiana Foroud
Grant NIH P30 AG 10133 Late Onset Alzheimer’s Disease: Supplement to the IADC 07/01/02 – 06/30/05. P.I. $150,000/year.
Grant NIH P30 AG 10133 Minority Supplement (Jeanne Dickens) to the IADC 07/01/01 – 06/30/04. P.I.. $167,252/year.
Grant NIH P30 AG 10133 Minority Supplement (Leticia Miravalle) to the IADC 12/01/03 – 06/30/06. P.I. $60,000/year.
Grant NIH R01 NS 37167. Title: Parkinson Disease Collaborative Study of Genetic Linkage. For the period 12/01/03 to 11/30/08. $1,652,000/year. P.I. Tatiana Foroud.
Grant NIH P50 AG 025688. Title: Emory Alzheimer Disease Research Center. For the period 6/1/2005 to 4/30/2010. $1,400,380/year. P.I. Allan Levey.
Grant NIH R01 NS 050227. Title: Ferritin Induced Neurodegeneration. For the period 7/01/2005 to 6/30/2010. $ 231,250/year. P.I. Ruben Vidal
Grant NIH PHS P30 AG 10133 (years 16-20) Title: Indiana Alzheimer Disease Center. For the period 7/1/06 to 6/30/11 $1,406,269/year. P.I.
Grant NIH U24 AG21886-01S1 National Cell Repository for Alzheimer’s Disease. For the Period 07/01/06 to 06/30/11. $625,271, P.I. Tatiana Foroud

Invited Addresses

International Symposium on the Physiology and Pathology of Dendrites, Max Planck Institute for Psychiatry, Munich, Federal Republic of Germany, September 1974.
University of Milano School of Medicine, Department of Pharmacology, Milano, Italy, September 1974.
Albert Einstein College of Medicine, Department of Pathology, Bronx, NY, December 1977.
Eli Lilly Research Laboratories, Indianapolis, IN, April 1978.
International Symposium on Peripheral Neuropathies, University of Milan, Milan, Italy, June 1978.
University of Pisa School of Medicine, Department of Neurology, Pisa, Italy, July 1978.
University of Florence School of Medicine, Department of Pharmacology, Florence, Italy, July 1978.
Meeting on "Aging of the Brain and Dementia" (Satellite meeting of the VII International Meeting of the International Society for Neurochemistry), Florence, Italy, August 1979.
University of Pisa School of Medicine, Department of Physiology, Pisa, Italy, September 1979.
Fidia Research Laboratories, Abano Terme, Italy, October 1980.
University of Pisa School of Medicine, Department of Physiology, Pisa, Italy, October 1980.
Institute for Basic Research in Mental Retardation. Staten Island, N.Y., November 1980.
"Workshop on Axoplasmic Transport", Schloss Elmau, Federal Republic of Germany, April 1981.
University of Rome School of Medicine, Department of Neurology, Rome, Italy, March 1982.
Conference on "The Aging of the Brain", Mantua, Italy, March 1982.
Neurological Institute "C. Besta", Milan, Italy, July 1983.
University of Maryland School of Medicine, Department of Pathology, Baltimore, MD, November 1983.
University of Michigan School of Medicine, Department of Psychiatry, Ann Arbor, MI, January 1984.
Wayne State University School of Medicine, Department of Pathology, Detroit, MI, January 1984.
Purdue University, Neuroscience Program, West Lafayette, IN, May 1984.
Elmhurst Memorial Hospital, Elmhurst, IL, September 1984.
Indiana Academy of Science, Bloomington, IN, September 1985.
Oklahoma Medical Research Foundation, Oklahoma City, OK, March 1986.
Ball State University, Department of Gerontology, Muncie, IN, April 1986.
Conference on "Trace Metals, Aging and Alzheimer Disease", Bethesda, MD, September 1986.
Butler University, Department of Biological Sciences, Indianapolis, IN, November 1986.
Neurological Institute "C. Besta", Milan, Italy, April 1987.
International Symposium on "New Trends in Aging Research", Sirmione, Italy, April 1987.
Cornell University Medical College, Burke Rehabilitation Center, White Plains, NY, May 1987.
Institute for Basic Research in Developmental Disabilities, Staten Island, NY, July 1987.
The Albany Medical College, Albany Medical Center, Department of Neurology, Albany, NY, July 1987.
Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, October 1987.
Meeting "Le Scienze Neurologiche Italiane nel mondo" Montedison Progetto Cultura, Milano, Italy, November 1987.
I.N.S.E.R.M., V-106, Histologie Normale et Pathologique Du System Nerveux, Hopital De La Salpetriere, Paris, France, November 1987.
Purdue University, Department of Biological Sciences, Lafayette, IN, January 1988
Neurological Institute "C. Besta", Milan, Italy, February 1988.
University of Connecticut, Department of Physiology and Neurobiology, Storrs, CT, March 1988.
Symposium "New Frontiers in Neuroscience: Neural Tissue Grafts and CNS Repair", Center for Neuroscience, College of Medicine, Univ. Tennessee, Memphis, TN, May 1988.
Indiana University School of Medicine, Northwest Center for Medical Education, Department of Physiology and Biophysics, Gary, IN, October 1988.
Symposium "Molecular Neurobiology, The Aging Process and Neurodegenerative Diseases", Indianapolis, IN, November 1988.
University of North Carolina School of Medicine, Department of Pathology, Chapel Hill, NC, February 1989.
Michigan State University, Neuroscience Program, East Lansing, MI, April 1989.
New York University Medical Center, Department of Pathology, New York, NY, May 1989.
Catholic University, School of Medicine, Department of Neurology, Rome, Italy, July 1989.
University of Siena School of Medicine, Institute of Neurological Sciences, Siena, Italy, July 1989.
Neurological Institute "C. Besta", Milan, Italy, August 1989.
Welborn Baptist Hospital, Evansville, IN, November 1989.
University of Pisa School of Medicine, Department of Pharmacology, Pisa, Italy, May 1990.
University of California School of Medicine, Department of Neurology, San Francisco, CA, June 1990.
Meeting "Dopamine '90. Dopaminergic systems and their regulations, Satellite Meeting of the XIth International Congress of International Union of Pharmacology. Como, Italy, July 1990.
Neurological Institute "C. Besta", Milan, Italy, January 1991.
2^nd National Parkinson Foundation "International Conference on Parkinson's Research", Miami Beach, FL, January 1991.
Cornell University, School of Art and Science, Department of Biology, Section of Neurobiology and Behavior, Ithaca, NY, April 1991.
University of Chicago, Department of Pharmacological and Physiological Sciences, Chicago, IL, May 1991.
Indianapolis Chapter Society for Neuroscience, Indianapolis, IN, May 1991.
University of Pittsburgh School of Medicine, Department of Pathology, Pittsburgh, PA, August 1991.
Conference "Prion diseases in humans and animals". London, England, September 2-4, 1991.
International Symposium "Monoaminergic cerebellar systems and ataxia". Lyon, France, September 11-12, 1991.
University of Pisa School of Medicine, Institute of Neurology, Pisa, Italy, October 28, 1991.
Kenneth M. Campione Visiting Professor of Neurology, Northwestern University Medical School, Department of Neurology, Chicago, IL, November 12, 1991.
Baylor College of Medicine, Department of Pathology, Houston, TX, February 3, 1992.
Baylor College of Medicine, Department of Neurology, Houston, TX, February 3, 1992.
IV Course sponsored by the Mariani Foundation and the Istituto Nazionale Carlo Besta on "Dystonia of childhood onset", Venezia, March 11-13, 1992.
Medical Research Council, Laboratory of Molecular Biology, Cambridge, England, March 18, 1992.
Institute for Basic Research in Developmental Disabilities, Staten Island, NY, April 20, 1992.
Third International Conference on Alzheimer Disease, Abano Terme, Italy, July 11-13, 1992.
"Verein für Psychiatrie und Neurologie" Wien, Austria, October 19, 1992.
XI Course of the Italian Society of Neurology, Bergamo, Italy, October 19-22, 1992.
31^st Annual Meeting of the American College of Neuropsychopharmacology, San Juan, Puerto Rico, December 14-18, 1992.
Meeting of the Future Technology Committee of the American College of Pathology, Snowbird, Utah, February 17-19, 1993.
First International Symposium "Transmissible and non transmissible neurodegenerative disorders: current update", Ocho Rios, Jamaica, February 28-March 5, 1993.
American College of Pathology, Seminar Series: New discoveries in the molecular pathology of neurological disease. Meeting of the American College of Pathology, Chicago, IL, March 30, 1993.
Neurological Institute "C. Besta", Milan, Italy, June 22, 1993.
American College of Pathology, Seminar Series: New discoveries in the molecular pathology of neurological disease. Meeting of the American College of Pathology, Orlando, FL, September, 1993.
Symposium "Research on mental retardation and dementia. The contributions of Robert D. Terry. NYS Institute for Basic Research, Staten Island, NY, November 6, 1993.
Symposium "State-of-the-art in Pathology and Laboratory Medicine: A course honoring Carleton D. Nordschow, M.D., Ph.D.. Indianapolis, IN, December 3, 1993.
"Third International Conference on Aluminum and Health", Miami, FL, February 6-10, 1994
Saint Louis University Medical Center, Department of Anatomy and Neurobiology, St. Louis, MO, February 23, 1994
Neurological Institute "C. Besta", Milan, Italy, May 25, 1994.
Symposium "Alzheimer 1994", Bergamo, Italy, May 26-28, 1994
University of Torino School of Medicine, Department of Neurology, Torino, Italy, June, 22-23, 1994
University of Pisa School of Medicine, Department of Neurology, Pisa, Italy, June 28, 1994
Medical Research Council, Laboratory of Molecular Biology, Cambridge, England, July 4, 1994.
Fourth International Conference on Alzheimer Disease and Related Disorders, Minneapolis, MN, July 29 - August 3, 1994.
Laboratory of Central Nervous Studies, Basic Neuroscience Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, Bethesda, MD, August 10, 1994
University of Pennsylvania School of Medicine, Department of Pathology and Laboratory Medicine, Philadelphia, PA, November 8, 1994
University of Louisville School of Medicine, Department of Anatomical Sciences and Neurobiology, Louisville, KY, March 13, 1995
Visiting Professor, Washington University School of Medicine, Department of Neurology, St. Louis, MO, April 18-19, 1995
VI Congress of the "Società Italiana di Neuroscienze", Milano, Italy, June 25-28, 1995
Fourth Joint American Society for Cell Biology/European Molecular Biology Organization Conference, Cambridge, England, August 5-10, 1995
Workshop "Molecular Biology of Prions and Pathology of Prion Diseases". The Banbury Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., November 5-8, 1995.
University of Washington School of Medicine, Department of Pathology, Seattle, WA, February 12, 1996.
"Mesencephalic dopaminergic cell cultures" sponsored by the National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD, March 11-12, 1996.
"Seminario Internacional de Encephalopatias Espongiformes" sponsored by the National Academy of Medicine and the National Academy of Agronomy and Veterinary Medicine, Buenos Aires, Argentina, April 29, 1996.
978^th Meeting of the Keio Medical Society, Keio University School of Medicine, Tokyo, Japan, July 22, 1996.
"Prion Disease Symposium" at National Institute on Health, Tokyo, Japan, July 23, 1996.
Fifth International Conference on Alzheimer Disease and Related Disorders, Osaka, Japan, July 24-29, 1996.
Satellite Symposium on Prion Diseases, Osaka, Japan, July 29, 1996.
"Prions, Brain Diseases in Animals and Humans", NATO Advanced Research Workshop, Erice, Italy, August 19-23, 1996.
Conference on chromosome 17-linked dementias, Michigan Alzheimer Disease Research Center, Ann Arbor, Michigan, October 4-6, 1996.
Maudsley Hospital, Institute of Psychiatry, Department of Neuropathology, London, England, October 21, 1996.
University of Siena School of Medicine, Institute of Neurological Sciences, Siena, Italy, October 31, 1996.
C.N.R. Institute of Biophysics, Pisa, Italy, November 4, 1996.
Department of Pathology, University of California, Department of Pathology, Irvine, California, December 2, 1996.
Visiting Professor, at the University of Oklahoma, Health Science Center, Oklahoma City, OK, March 19, 1997.
Keynote Speaker, XXXIII Congresso Associazione Italiana Di Neuropatologia, Pisa, Italy, June 2, 1997.
Presidential Address, 73^rd Annual Meeting of the American Association of Neuropathologists, Pittsburgh, PA, June 15, 1997.
22^nd Session of the International Seminars on Planetary Emergencies, Erice, Italy, August 19-24, 1997.
Plenary Lecture, XIII International Congress of Neuropathology, Perth, Australia, September 7-12, 1997.
Visiting Scientist, MRC Cambridge Center for Brain Repair, University of Cambridge, Cambridge, England, March 12, 1998.
Institute of Neurology, Queen Square, University College London, London, England, March 13, 1998.
College of American Pathologists, Los Angeles, CA, April 4-8, 1998.
European Concerted Action on Transmissible Spongiform Encephalopathies, Baden, Austria, May 15-17, 1998.
6^th International Conference on Alzheimer's Disease and Related Disorders, Amsterdam, Netherlands, July 18-23, 1998.
College of Physicians & Surgeons Biomedical Sciences Symposium on "Advances in Neurodegenerative Disease", Arden House, Harriman, New York, July 31-August 2, 1998.
Keynote speaker, VIII International Symposium on Amyloidosis, Rochester, MN, August 7-11, 1998
International Seminars On Planetary Emergencies, Erice, Italy, August 19-24, 1998
Keynote speaker, XXII International Congress of the International Academy of Pathology, Nice, France, October 18-23, 1998
Alzheimer Disease Directors Meeting, Los Angeles, CA, November 7, 1998
14^th Course of the Italian Society of Neurology, Pisa, Italy, November 10-14, 1998.
Visiting Professor, Cognitive Neurology and Alzheimer Disease Center, Northwestern University Medical School, Alzheimer Disease Seminars, Chicago, IL, March 25, 1999
Potamkin Award Speaker, American Academy of Neurology, Toronto, Ontario, Canada, April 20, 1999
Invited speaker, IBC's Eight Annual Conference on Alzheimer's Disease, Boston, MA, May 20, 1999
Invited speaker, University of Rome "La Sapienza", Department of Experimental Medicine and Pathology, Rome, Italy, May 31 1999.
European Second Concerted Action Scientific meeting on Transmissible Spongiform Encephalopathies: Update on Neuropathology and Phenotypic Variation, Baden, Austria, June 4-6, 1999.
Keynote speaker, 12th Summer Symposium, Alzheimer Association Greater Cincinnati Chapter, August 6, 1999
International Seminars On Planetary Emergencies, Erice, Italy, August 19-24, 1999
Invited speaker, Neurogenetics Department Imperial College School of Medicine, St. Mary's Campus,"Evolution of our understanding of Gerstmann-Sträussler-Scheinker Disease" London, England, August 26, 1999.
Invited speaker, Alzheimer 2000 Update sulle Demenze, Arezzo, Italy, October 29-30, 1999.
Invited speaker, Ninth Meeting of the International Study Group on the Pharmacology of Memory Disorders Associated with Aging, “Progress in hereditary tauopathies: a mutation in the Tau gene (G389R) causes a Pick disease-like syndrome”, Zurich, Switzerland, February 18-20, 2000.
Keynote speaker, Indiana University School of Medicine Scientific Session, March 31, 2000.
Invited speaker, Meeting the French Society of Neuropathology, Toulouse, France, May 20, 2000.
Invited speaker, Concerted Action Human Transmissible spongiform encephalopathies (prion diseases), Baden, Austria, May 28, 2000.
Invited speaker, 76^th Annual Meeting of the American Association of Neuropathologists Hindlimb paralysis and cerebellar PrP deposits in transgenic mice over-expressing wild-type PrP. June 7, 2000.
Invited speaker, University of Pisa, Department of Neuroscience, Pisa, Italy, June 15, 2000.
Invited speaker, Alzheimer’s disease vs. other degenerative dementias: from biology to treatment. University of Perugia, Department of Neuroscience, Perugia, Italy, June 17, 2000.
Visiting Professor, Department of Psychiatric Research, Zurich, Switzerland June 21, 2000.
Keynote Lecturer, World Alzheimer Congress, Alzheimer Association, Washington, D.C. July 9-13, 2000.
Visiting Professor, Department of Neurology and Alzheimer Disease Center, Mayo Clinic, Rochester, MN. October 23-24, 2000.
Grand Rounds, Department of Pathology and Laboratory Medicine, Indianapolis, IN. November 14, 2000.
Visiting Professor, University of Florence, Florence, Italy. March 26, 2001.
Invited Speaker, National Council for Research, Pisa, Italy. March 28, 2001.
Invited Speaker, Joint Meeting of the German and Hungarian Societies of Neuropathology, Budapest, Hungary. March 30, 2001.
Invited Speaker, Emory University, Atlanta, GA. April 12, 2001.
Visiting Professor, New York University School of Medicine, New York, NY. April 19, 2001.
Visiting Professor, State University of New York, Brooklyn, NY. April 20, 2001.
Invited Speaker, Oregon Health Sciences University, Portland, OR. June 27, 2001.
Invited Speaker, World Federation of Scientists, Erice, Italy. August 24, 2001.
Invited Speaker, Indiana University School of Medicine, Indianapolis, IN. January 24, 2002.
Invited Speaker, Nothwestern University School of Medicine, Chicago, IL. March 14, 2002.
Invited Speaker, Mayo Clinic, Jacksonville, FL. April 19, 2002.
Invited Speaker, 7^th European Congress of Neuropathology “Neuropathology 2002”, Helsinki, Finland. July 14, 2002.
Invited Speaker, 7^th European Congress of Neuropathology “Neuropathology 2002”, Helsinki, Finland. July 16, 2002.
Invited Speaker, 8^th International Conference on Alzheimer Disease and Related Disorders “Alzheimer 2002”, Stockholm, Sweden, July 22, 2002.
Invited Speaker, World Federation of Scientists, Erice, Italy. August 24, 2002.
Invited Speaker, Symposium of the Society for Experimental Neuropathology, New York, NY. October 13, 2002.
Invited Speaker, Scientific Meeting of the Human Transmissible Spongiform Encephalopathies: The Neuropathology Network (Prionet) Baden, Austria. November 3, 2002.
Invited Speaker, Movement Disorder Society, Miami, FL, November 12, 2002.
Invited Speaker, International Conference on Cerebral Amyloid Angiopathy, Newcastle upon Tyne, UK, December 4, 2002.
Invited Speaker, Yale University, February 27, 2003
Invited Speaker, 39^th Annual Meeting of the Italian Association of Neuropathology, Siena, Italy, June 9, 2003
Invited Speaker, Special Course, 39^th Annual Meeting of the Italian Association of Neuropathology, Siena, Italy, June 10, 2003
Invited Speaker, From Prion to Prion Diseases: Pathogenesis, Diagnosis, Treatment. Troina, Italy October 18, 2003
Invited Speaker, Scientific Meeting of the Human Transmissible Spongiform Encephalopathies: The Neuropathology Network (Prionet) Baden, Austria. November 2, 2003
Visiting Professor, University of Colorado, Denver, CO. January 21, 2004
Visiting Professor, University of Pisa, Pisa, Italy June 4, 2004
Visiting Professor, University of Pisa, Pisa, Italy June 5, 2004
Visiting Professor, University of Pisa, Pisa, Italy June 7, 2004
Visiting Professor, University of Pisa, Pisa, Italy June 8, 2004
Visiting Professor, University of Pisa, Pisa, Italy June 9, 2004
Visiting Professor, University of Genova, Genova, Italy June 10, 2004
Invited Speaker, World Federation of Scientists, Erice, Italy. August 21, 2004
Visiting Professor, University of Pisa, Pisa, Italy November 12, 2004
Visiting Professor, University of Pisa, Pisa, Italy November 15, 2004
Visiting Professor, Harvard University, McLean Hospital, Belmont, MA January 3, 2005
Invited Speaker Laurea Honoris Causa, University of Siena, Siena, Italy January 21, 2005
Visiting Professor, University of Siena, Siena, Italy January 24, 2005
Invited Speaker, Rush University School of Medicine, Chicago, IL February 3, 2005
Invited Speaker, Indiana University School of Medicine, Indianapolis, IN March 3, 2005
Invited Speaker, American Academy of Neurology, Miami, FL April 10, 2005
Invited Speaker, 46^th Annual Meeting of the Japanese Society of Neuropathology, Utsunomiya, Japan May 13, 2005
Invited Speaker, Keio University, Tokyo, Japan May 16, 2005
Invited Speaker, Nagoya University, Nagoya, Japan May 17, 2005
Invited Speaker, Kyoto Prefectural University, Kyoto, Japan May 18, 2005
Invited Speaker, Kanazawa University, Kanazawa, Japan May 20, 2005
Invited Speaker, Brain Research Institute, Niigata University, Niigata, Japan May 23, 2005
Invited Speaker, Tokyo Institute of Psychiatry, Tokyo, Japan May 24, 2005
Invited Speaker, 46^th Annual Meeting of the Japanese Neurological Society, Kagoshima, Japan May 26, 2005
Invited Speaker, “Saul R. Korey Lecture”, 81^st Annual Meeting of the American Association of Neuropathologists, Arlington, VA June 11, 2005
Invited Speaker, 8^th European Congress of Neuropathology, Amsterdam, The Netherlands June 27, 2005
Invited Speaker, University of Verona, Verona, Italy June 30, 2005
Invited Speaker, University of Verona, Verona, Italy July 7, 2005
Invited Speaker, 7^th Annual Meeting of the Udall Centers of Excellence for Parkinson’s Disease Research, Boston, MA September 21, 2005
Visiting Professor, University of Rochester, Rochester, NY September 30, 2005
Invited Speaker, Columbia University, New York, NY December 8, 2005
Invited Speaker, State University of New York Downstate Medical Center, Brooklyn, NY March 6, 2006
Invited Speaker, Emory University Atlanta, GA March 17, 2006
Invited Speaker, Prion Science: Beginning of the End, or just End of the Beginning? Baden, Austria, May 21, 2006
Invited Speaker, Greater Cincinnati Chapter of the Alzheimer’s Association, Cincinnati, OH, June 27, 2006
Invited Speaker, CJD Foundation, Washington D.C., July 8, 2006
Invited Speaker, 5^th International Conference on Frontotemporal Dementias, San Francisco, CA, September 6, 2006
Invited Speaker, Prion 2006: Strategies, advances and trends towards protection of society, Torino, Italy, October 5, 2006
Invited Speaker, University of Cincinnati, Cincinnati, OH, November 16, 2006 (3 presentations)
Invited Speaker, British Neuropathological Society, Alfred Meyer Lecture, January 10, 2007
Visiting Lecturer, University of Cincinnati School of Medicine, February 28, 2007 (2 presentations)
Invited Speaker, Eighth International Conference AD/PD 2007, March 15, 2007
Invited Speaker, National Institutes on Health, NIAID, Rocky Mountain Laboratories, April 19, 2007.
Invited Speaker, Wright-Patterson Medical Center, May 10, 2007
Invited Speaker, CJD Foundation, Washington D.C., July 7, 2007
Invited Speaker, World Federation of Scientists, Erice, Italy. August 19, 2007
Invited Speaker, Two Tasks for the 21^st Century: Treating and Preventing Alzheimer’s Disease, Erice, Italy. August 25, 2007
Invited Speaker, XXXVIII Congress Italian Society of Neurology, October 15, 2007
Invited Speaker, University of Pisa, Pisa, Italy October 17, 2007

Invited Speaker, University of Verona, Verona, Italy June 30, 2005

Meeting Organization

Symposium on Neuropsychiatric Disorders, Permanent Monitoring Panel on Brain and Behavior, World Federation of Scientists, Erice, Italy. August 24-25, 2002.
Symposium: “The Crisis of Losing Minds: The Epidemic of Alzheimer’s Disease in the 21^st Century”, Permanent Monitoring Panel on Brain and Behavior, World Federation of Scientists, Erice, Italy. August 24, 2007

Bibliography

Papers

Cassano, G.B.; Ghetti, B.; Gliozzi, E.; and Hansson, E.: Autoradiographic distribution study of "Short-Acting" and "Long-Acting" barbiturates: S35-Thiopentone and C14-Phenobarbitone. British Journal of Anaesthesia, 39:11-20, 1967.
Cassano, G.B.; Placidi, G.F.; and Ghetti, B.: Studio comparativo della distribuzione fetale di alcuni farmaci psicotropi ed ipnotici. Rivista di Neurobiologia, 13:105-114, 1967.
Ghetti, B.; Cassano, G.B.; Amaducci, L.; and Pepeu, G.: Studio della distribuzione nel topo e dell' incorporazione nel cervello di ratto della P32-Fosfoserina e del P32-Fosfato, Quaderni di Acta Neurologica, 26:160-165, 1967.
Gliozzi, E.; Ghetti, B.; and Cassano, G.B.: Rapporto tra distribuzione e proprietà farmacodinamiche dello S35-Tiopental e del C14-Fenobarbital. Quaderni di Acta Neurologica, 26:166-170, 1967.
Castrogiovanni, P.; Ghetti, B.; and Cassano, G.B.: Valore e significato dello "studio pilota" nella psicofarmacologia clinica (sperimentazione clinica del P4657 B: tiotixene). Quaderni di Acta Neurologica, 26:171-176, 1967.
Pardera, G.; and Ghetti, B.; Rilievi clinici sulla validità dell'impiego precoce dell'ESK terapia nelle psicosi amenziali. Neopsichiatria, 34:31-41, 1968.
Bertolino, A.; Fiore, C.; Morcaldi, L.; Pinto, L.; Ghetti, B.; and Guazzi, G.C.: La teleangectasia universale, congenita, eritematosa di Bloom associata ad areflessia osteo-tendinea ed oligofrenia: studio del primo caso italiano. Rassegna Internazionale di Clinica e Terapia, 49:1331-1347, 1968.
Guazzi, G.C.; Ghetti, B.; Bertolino, A.; Fiore, C.; Del Vecchio, M.; and Striano, S.: Epilessia mioclonica giovanile con macchia rosso ciliegia al fondo dell'occhio: studio genetico e clinico. Folia Neuro Psychiatrica, 11:737-758, 1968.
Cassano, G.B.; Gliozzi, E.; and Ghetti, B.: The relationship between dynamic features of the brain distribution of C14-Chlordiazepoxide and motor behaviour changes in mice. IN: A. Cerletti and F. J. Bové (Eds.), The present status of psychotropic drugs, Excerpta Medica International Congress Series, Vol. 180:342-346, Excerpta Medica Foundation, Amsterdam, 1969.
Ghetti, B.; Gliozzi, E.; and Cassano, G.B.: Placental transfer and foetal distribution of psychoactive and hypnotic drugs. IN: A. Cerletti and F. J. Bové (Eds.), The present status of psychotropic drugs, Excerpta Medica International Congress Series, Vol. 180:349-352, Excerpta Medica Foundation, Amsterdam, 1969.
Ghetti, B.; Devoto, A.; Castrogiovanni, P.; and Cassano, G.B.: Un nuovo derivato tioxantenico: il tiotixene (P-4657B) studio pilota pluricentrico. Neopsichiatria, 35:1-13, 1969.
Cassano, G.B.; Viola, P.L.; Ghetti, B.; and Amaducci, L.: The distribution of inhaled mercury (Hg203) vapors in the brain of rats and mice. Journal of Neuropathology and Experimental Neurology, 28:308-320, 1969.
Fiore, C.; Ghetti, B.; Bertolino, A.; Fazzi, R.; and Guazzi, G.C.: Atassia-teleangectasia di M.me Louis-Bar: studio del primo caso italiano. Rassegna Internazionale di Clinica e Terapia, 50:589-601, 1970.
Guazzi, G.C.; Ghetti, B.; Del Vecchio, M.; and Striano, S.: Studio genetico di una famiglia di epilessia-mioclonica con macchia rosso ciliegia al fondo dell'occhio. Bollettino della Società Italiana di Biologia Sperimentale, 46:452-455, 1970.
Ghetti, B.; Cecio, A.; De Masi, R.V.; and Guazzi, G.C.: Studio istologico ed istochimico della biopsia epatica di una paziente di 29 anni affetta da epilessia-mioclonia con macchia rosso-ciliegia al fondo dell'occhio. Bollettino della Società Italiana di Biologia Sperimentale, 46:455-457, 1970.
Cecio, A.; Ghetti, B.; De Masi, R.V.; and Guazzi, G.C.: Studio ultrastrutturale della biopsia epatica di una paziente di 29 anni affetta da epilessia-mioclonia con macchia rosso-ciliegia al fondo dell'occhio. Bollettino della Società Italiana di Biologia Sperimentale, 46:457-459, 1970.
Ghetti, B.; Guazzi, G.C.; De Masi, R.V.; and Cecio, A.: Epilessia mioclonica giovanile con macchia rosso-ciliegia al fordo dell'occhio. Studio istologico ed ultrastrutturale della biopsia epatica. Acta Neurologica, 25:252-260, 1970.
Guazzi, G.C.; Ventruto, V.; Del Vecchio, M.; Fazzi, G.R.; Ghetti, B.; Salvati, G.; Vertucci, P.; and Bianchi, A.: Studio genetico ed immunologico di due famiglie con atassia-telangectasia di M.me Louis-Bar. Acta Neurologica, 25:551-577, 1970.
Ghetti, B.; Amati, A.; Turra, M.V.; Pacini, A.; Del Vecchio, M.; and Guazzi, G.C.: Werdnig-Hoffmann-Wohlfart-Kugelberg-Welander disease: nosological unity and clinical variability in intrafamilial cases. Acta Geneticae Medicae et Gemellologiae, 20:43-58, 1971.
Del Vecchio, M.; Amati, A.; Cedrola, C.; Cerillo, A.; Ghetti, B.; Signorelli, C.; and Guazzi, G.C.: Studio genetico di due famiglie (23 soggetti) affette da malattia di von Recklinghausen and eredità autosomica dominante. Acta Neurologica, 26:319-360, 1971.
Bravaccio, F.; Paolozzi, C.; Amati, A.; Del Vecchio, M.; Ghetti, B.; Tripaldelli, B.; and Guazzi, G.C.: Atrofia cerebellare tardiva con areflessia osteotendinea ed oftalmoplegia progressiva ad eredità dominante autosomica. Studio longitudinale in 6 generazioni di una famiglia. Acta Neurologica, 26:261-374, 1971.
Castrogiovanni, P.; Placidi, G.F.; Maggini, C.; Ghetti, B.; and Cassano, G.B.: Clinical investigation of doxepine in depressed patients. Pilot open study controlled double blind trial versus imipramine, and all-night polygraphic study. Pharmakopsychiatrie, Neuropsychopharmakologie, 4:170-181, 1971.
Raine, C.S.; Ghetti, B.; and Shelanski, M.L.: On the association between microtubules and mitochondria within axons. Brain Research, 34:389-393, 1971.
Ghetti, B.; and Wisniewski, H.M.: On degeneration of terminals in the cat striate cortex. Brain Research, 44:630-635, 1972.
Ghetti, B.; Horoupian, D.S.; and Wisniewski, H.M.: Transsynaptic response of the lateral geniculate nucleus and the pattern of degeneration of the nerve terminals in the rhesus monkey after eye enucleation. Brain Research, 45:31-48, 1972.
Wisniewski, H.M.; Ghetti, B.; and Horoupian, D.S.: The fate of synaptic membranes of the degenerating optic nerve terminals and their role in the pathomechanism of transsynaptic changes. Journal of Neurocytology, 1:297-310, 1972.
Guazzi, G.C.; Ghetti, B.; Barbieri, F.; and Cecio, A.: Myoclonus-epilepsy with cherry-red spot in adult: a peculiar form of mucopolysaccharidosis. A clinical, genetical, chemical and ultrastructural study. Acta Neurologica, 28:542-549, 1973.
Horoupian, D.S.; Ghetti, B.; and Wisniewski, H.M.: Retrograde transneuronal degeneration of optic fiber terminals in lateral geniculate nucleus of rhesus monkey. Brain Research, 49:257-275, 1973.
Wisniewski, H.M.; Ghetti, B.; and Terry, R.D.: Neuritic (senile) plaques and filamentous changes in aged rhesus monkey. Journal of Neuropathology and Experimental Neurology, 32:566-584, 1973.
Kristensson, K.; Ghetti, B.; and Wisniewski, H.M.: Study on the propagation of Herpes Simplex virus (type 2) into the brain after intraocular injection. Brain Research, 69:189-201, 1974.
Cook, R.D.; Ghetti, B.; and Wisniewski, H.M.: The pattern of Wallerian degeneration in the optic nerve of newborn kittens: an ultrastructural study. Brain Research, 75:261-275, 1974.
Korthals, J.K.; Wisniewski, H.M.; Ghetti, B.; and Cook, R.D.: The fate of the axon and its terminal in the Pacinian corpuscle following sciatic nerve section. Journal of Neurocytology, 3:385-403, 1974.
Ghetti, B.; Horoupian, D.S.; and Wisniewski, H.M.: Acute and long-term transneuronal response of dendrites of lateral geniculate neurons following transection of the primary visual afferent pathway. IN: G. W. Kreutzberg (Ed.), Physiology and Pathology of Dendrites, Advances in Neurology, Vol. 12:401-424, Raven Press, New York, NY, 1975.
Ghetti, B.; and Ochs, S.: On the relation between microtubule density and axoplasmic transport in nerves treated with Maytansine in vitro. IN: N. Canal and G. Pozza (Eds.) Peripheral Neuropathies, Developments in Neurology, Vol. 1:177-186, Elsevier North Holland Biomedical Press, Amsterdam, 1978.
Ghetti, B.: Induction of neurofibrillary degeneration following treatment with maytansine in vivo. Brain Research, 163:9-19, 1979.
Maggi, A.; Schmidt, M.J.; Ghetti, B.; and Enna, S.J.: Effect of aging on neurotransmitter receptor binding in rat and human brain. Life Science, 24:367-374, 1979.
Schmidt, M.J.; and Ghetti, B.: Exaggerated norepinephrine-stimulated ac-cumulation of cyclic AMP in vitro in cerebellar slices from pcd mutant mice following Purkinje cell loss. Journal of Neural Transmission, 48:49-56, 1980.
Schmidt, M.J.; Truex, L.L.; Ghetti, B.; and Routtenberg, A.: Cyclic AMP-dependent protein kinase activity in human brain across age. Journal of Neurochemistry, 35:261-265, 1980.
Kim, S.U.; Tomonaga, M.; and Ghetti, B.: Neurofibrillary degeneration in cultured adult mouse neurons induced by maytansine. Acta Neuropathologica (Berl), 52:161-164, 1980.
Ghetti, B.: Experimental studies on neurofibrillary degeneration, IN: L. Amaducci, A. N. Davison, and P. Antuono (Eds.), Aging of the Brain and Dementia, Aging, Vol. 13:183-198, Raven Press, New York, NY, 1980.
Ghetti, B.; Truex, L.; Sawyer, B.; Strada, S.; and Schmidt, M.J.: Exaggerated cyclic AMP accumulation and glial cell reaction in the cerebellum during Purkinje cell degeneration in pcd mutant mice. Journal of Neuroscience Research, 6:789-801, 1981.
Routtenberg, A.; Morgan, D.; Conway, R.; Schmidt, M.J.; and Ghetti, B.: Human brain protein phosphorylation in vitro: cyclic AMP stimulation of electrophoretically-separated substrates. Brain Research, 222:323-333, 1981.
Ghetti, B.; Fuller, R.W.; Sawyer, B.D.; Hemrick-Luecke, S.K.; and Schmidt, M.J.: Purkinje cell loss and the noradrenergic system in the cerebellum of pcd mutant mice. Brain Research Bulletin, 7:711-714, 1981.
Schmidt, M.J.; Sawyer, B.D.; Perry, K.W.; Fuller, R.W.; Foreman, M.M.; and Ghetti, B.: Dopamine deficiency in the weaver mutant mouse. Journal of Neuroscience, 2:376-380, 1982.
Ghetti, B.; Alyea, C.; Norton, J.; and Ochs, S.: Effects of vinblastine on microtubule density in relation to axoplasmic transport. IN: D. Weiss (Ed.), Axoplasmic Transport, 322-327, Springer-Verlag, New York, Wien, 1982.
Schwartz, J.P.; Ghetti, B.; Truex, L.; and Schmidt, M.J.: Increase of a nerve growth factor-like protein in the cerebellum of pcd mutant mice. Journal of Neuroscience Research, 8:205-211, 1982.
Bugiani, O.; and Ghetti, B.: Progressing encephalomyelopathy with muscular atrophy, induced by aluminum powder. Neurobiology of Aging, 3:209-222, 1982.
Gambetti, P.; Shecket, G.; Ghetti, B.; Hirano, A.; and Dahl, D.: Neurofibrillary changes in human brain. An immunocytochemical study with neurofilament antisera. Journal of Neuropathology and Experimental Neurology, 42:69-79, 1983.
Bugiani, O.; and Ghetti, B.: Effects of experimental prolonged exposure to Aluminum on the nervous system. IN: D. Samuel, et al (Eds.), The Aging of the Brain, Aging Vol. 22:271-275, Raven Press, New York, NY, 1983.
Vaccarino, F.M.; Ghetti, B.; Wade, S.E.; Rea, M.A.; and Aprison, M.H.: Loss of Purkinje cell-associated benzodiazepine receptors spares a high affinity subpopulation: A study with pcd mutant mice. Journal of Neuroscience Research, 9:311-323, 1983.
Ghetti, B.; and Gambetti, P.: Comparative immunocytochemical charac-terization of neurofibrillary tangles in experimental maytansine and aluminum encephalopathies. Brain Research, 277:388-393, 1983.
Azzarelli, B.; Muller, J.; Ghetti, B.; Dyken, M.; and Conneally P.M.: Cerebellar plaques in familial Alzheimer's disease (Gerstmann-Sträussler-Scheinker Variant?). Acta Neuropathologica (Berl), 65:235-246, 1985.
Ghetti, B.; Musicco, M.; Norton, J.; and Bugiani, O.: Nerve cell loss in the progressive encephalopathy induced by aluminum powder: A morphologic and semiquantitative study of the Purkinje cell. Neuropathology and Applied Neurobiology 11:31-53, 1985.
Sato, Y.; Kim, S.U.; and Ghetti, B.: Induction of neurofibrillary tangles in cultured mouse neurons by maytanprine. Journal of the Neurological Sciences, 68:191-203, 1985.
Bugiani, O.; Brancaccio, D.; and Ghetti, B.: Progressive dialytic encepha-lopathy and the problem of aluminum neurotoxicity. Clinical Nephrology, 24(Suppl. 1): 20-25, 1985.
Vaccarino, F.M.; Ghetti, B.; and Nurnberger, J.I.: Residual benzodiazepine (BZ) binding in the cortex of pcd mutant cerebella and qualitative BZ binding in the deep cerebellar nuclei of control and mutant mice: An autoradiographic study. Brain Research, 343:70-78, 1985.
Triarhou, L.C.; Norton, J.; Bugiani, O.; and Ghetti, B.: Ventral root axonopathy and its relation to the neurofibrillary degeneration of lower motor neurones in aluminum-induced encephalomyelopathy. Neuropathology and Applied Neurobiology, 11:407-430, 1985.
Felten, D.L.; Felten, S.Y.; Perry, K.W.; Fuller, R.W.; Nurnberger, J.I.; and Ghetti, B.: Noradrenergic innervation of the cerebellar cortex in normal and Purkinje cell degeneration (pcd) mice: Evidence for long term survival following loss of the two major cerebellar cortical neuronal populations. Neuroscience, 18:783-793, 1986.
Triarhou, L.C; and Ghetti, B.: Monoaminergic nerve terminals in the cerebellar cortex of Purkinje cell degeneration mutant mice: Fine structural integrity and modification of cellular environs following loss of Purkinje and granule cells. Neuroscience, 18:795-807, 1986.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Transplantation of ventral mesencephalic anlagen to hosts with genetic nigrostriatal dopamine deficiency. Proceedings of the National Academy of Science, USA, 83:8789-8793, 1986.
Ghetti, B.; and Bugiani, O.: "Aluminum's disease and Alzheimer's disease. Neurobiology of Aging, 7:536-537, 1986.
Gupta, M.; Felten, D.L; and Ghetti, B.: Selective loss of monoaminergic neurons in weaver mutant mice an immunocytochemical study. Brain Research, 402:379-382, 1987.
Ghetti, B.; Perry, K.W.; and Fuller, R.W.: Norepinephrine metabolism in the cerebellum of the Purkinje cell degeneration (pcd) mutant mouse. Neurochemistry International, 10:39-47, 1987.
Triarhou, L.C.; Norton, J.; and Ghetti, B.: Anterograde transsynaptic degeneration in the deep cerebellar nuclei of "Purkinje cell degeneration" (pcd) mutant mice. Experimental Brain Research, 66:577-588, 1987.
Ghetti, B.; Norton, J.; and Triarhou, L.C.: Nerve cell atrophy and loss in the inferior olivary complex of "Purkinje cell degeneration" (pcd) mutant mice. The Journal of Comparative Neurology, 260:409-422, 1987.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Transplantation of cerebellar anlagen to hosts with genetic cerebellocortical atrophy. Anatomy and Embryology, 176:145-154, 1987.
Hofstetter, J.R.; Vincent, I.; Bugiani, O.; Ghetti, B.; and Richter, J.A.: Aluminum induced decreases in choline acetyltransferase, tyrosine hydroxylase, and glutamate decarboxylase in selected regions of rabbit brain. Neurochemical Pathology, 6:177-193, 1987.
Low, W.C., Triarhou, L.C.; and Ghetti, B.: Cerebellar transplants into mutant mice with Purkinje and granule cell degeneration. IN: E.C. Azmitia and A. Björklund (Eds.), Cell and Tissue Transplantation into the Adult Brain. Annals of the New York Academy of Sciences, New York, 495:740-744, 1987.
Kaseda, Y.; Ghetti, B.; Low, W.C.; Richter, J.A.; and Simon, J.R.: Dopamine D2 receptors increase in the dorsolateral striatum of weaver mutant mice. Brain Research, 422:178-181, 1987.
Triarhou, L.C.; and Ghetti, B.: Neuroanatomical substrate of behavioural impairment in weaver mutant mice. Experimental Brain Research, 68:434-435, 1987.
Low, W.C.; Triarhou, L.C.; Kaseda, Y.; Norton, J.; and Ghetti, B.: Functional innervation of the striatum by ventral mesencephalic grafts in mice with inherited nigrostriatal dopamine deficiency. Brain Research, 435:315-321, 1987.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Synaptic investment of striatal cellular domains by grafted dopamine neurones in mice with genetic mesostriatal dopamine deficiency. Naturwissenschaften, 74:591-593, 1987.
Triarhou, L.C.; and Ghetti, B.: Therapeutic prospects in Parkinson disease: Insights from experimental models of intracerebral transplantation. Acta Medica Hellenica, 53:359-364, 1987.
McBride, W.J.; and Ghetti, B.: Changes in the contents of glutamate and GABA in the cerebellar vermis and hemispheres of the Purkinje cell degeneration (pcd) mutant. Neurochemical Research, 13:121-125, 1988.
Triarhou, L.C.; Norton, J.; and Ghetti, B.: Mesencephalic dopamine cell deficit involves areas A8, A9 and A10 in weaver mutant mice. Experimental Brain Research, 70:256-265, 1988.
Triarhou, L.C.; and Ghetti, B.: Prospectives for repair in Parkinson disease: Insights from experimental models of dopamine neuron grafting. Federazione Medica, 41:149-154, 1988.
Triarhou, L.C.; Norton, J. and Ghetti, B.: Synaptic connectivity of tyrosine hydroxylase immunoreactive nerve terminals in the striatum of normal, heterozygous and homozygous weaver mutant mice. Journal of Neurocytology, 17:221-232, 1988.
Triarhou, L.C.; Low, W.C.; Norton, J.; and Ghetti, B.: Reinstatement of synaptic connectivity in the striatum of weaver mutant mice following transplantation of ventral mesencephalic anlagen. Journal of Neurocytology, 17:233-243, 1988.
Mendelsohn, L.G.; Smith, M.C.; Lucaites, V.L.; Kerchner, G.A.; and Ghetti, B.: Autoradiographic localization of insulin-like growth factor II receptors in cerebellar cortex of weaver and Purkinje cell degeneration mutant mice. Brain Research, 458:361-366, 1988.
Ghetti, B.; Perry, K.W.; and Fuller, R.W.: Serotonin concentration and turnover in cerebellum and other brain regions of pcd mutant mice. Brain Research, 458:367-371, 1988.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Layer-specific innervation of the dopamine-deficient frontal cortex in weaver mutant mice by grafted mesencephalic dopaminergic neurones". Cell and Tissue Research, 254:11-15, 1988.
Bugiani, O.; and Ghetti, B.: Seizures in experimental encephalomyelopathy induced by aluminum. Possible mechanisms and correlates with human pathology. IN: G. Broggi (Ed.), The Rational Basis of the Surgical Treatment of Epilepsies, Current Problems in Epilepsy, Volume 5:143-147. John Libbey, London, England, 1988.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Genetic mesotelencephalic dopamine deficiency in weaver mutant mice: Reinstatement of neuronal connectivity by solid grafts of foetal mesencephalon. IN: G. Pepeu, B. Tomlinson, and C.M. Wischik (Eds.), New Trends in Aging Research, Fidia Research Series, Vol. 15: 183-192, Liviana Press, Padova, 1988.
Giaccone, G.; Tagliavini, F.; Street, J.S.; Ghetti, B.; and Bugiani, O.: Progressive supranuclear palsy with hypertrophy of the olives. An immunocytochemical study of the cytoskeleton of argyrophilic neurons. Acta Neuropathologica (Berl), 77:14-20, 1988.
Chang, A.C.; Triarhou, L.C.; Alyea, C.J.; Low, W.C.; and Ghetti, B.: Developmental expression of polypeptide PEP-19 in cerebellar cell suspensions transplanted into the cerebellum of pcd mutant mice. Experimental Brain Research, 76:639-645, 1989.
Doucet, G.; Brundin, P.; Seth, S.; Murata, Y.; Strecker, R.E.; Triarhou, L.C.; Ghetti, B.; and Björklund, A.: Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: A quantitative radioautographic study of [3H]dopamine uptake. Experimental Brain Research, 77:552-568, 1989.
Bugiani, O.; Giaccone, G.; Frangione, B.; Ghetti, B.; and Tagliavini, F.: Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system. Neuroscience Letters, 103:263-268, 1989.
Triarhou, L.C.; and Ghetti, B.: The dendritic dopamine projection of the substantia nigra: phenotypic denominator of weaver gene action in hetero- and homozygosity. Brain Research, 501:373-381, 1989.
Farlow, M.R.; Yee, R.D.; Dlouhy, S.R.; Conneally, P.M.; Azzarelli, B.; and Ghetti, B.: Gerstmann-Sträussler-Scheinker disease: I. Extending the clinical spectrum. Neurology, 39:1446-1452, 1989.
Ghetti, B.; Tagliavini, F.; Masters, C.L.; Beyreuther, K.; Giaccone, G.; Verga, L.; Farlow, M.R.; Conneally, P.M.; Dlouhy, S.R.; Azzarelli, B.; and Bugiani, O.: Gerstmann-Sträussler-Scheinker disease: II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family. Neurology, 39:1453-1461, 1989.
Triarhou, L.C.; Brundin, P.; Doucet, G.; Norton, J.; Björklund, A.; and Ghetti, B.: Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: Ultrastructural relationships of dopaminergic dendrites and axons issued from the graft. Experimental Brain Research 79:3-17, 1990.
Bugiani, O.; and Ghetti, B.: Aluminum encephalopathy: experimental vs human. IN: M.E. DeBroe and J.W. Coburn (Eds.)., Aluminum and renal failure, pp. 109-125, Kluwer Academic Publishers, Dordrecht, The Netherlands, 1990.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Dopamine neuron grafting to the weaver mouse neostriatum. IN: S. Dunnett and S.-J. Richards (Eds.), Neural transplantation: From molecular basis to clinical application. Progress in Brain Research, Vol. 82:187-195, Elsevier, Amsterdam, The Netherlands, 1990.
Ghetti, B.; Triarhou, L.C.; Alyea, C.J.; Low, W.C.; and Chang, A.C.: Timing of neuronal replacement in cerebellar degenerative ataxia of Purkinje cell type. IN: S. Dunnett and S.J. Richards (Eds.), Neural transplantation: From molecular basis to clinical application. Progress in Brain Research, Vol. 82:197-202, Elsevier, Amsterdam, The Netherlands, 1990.
Giaccone, G.; Tagliavini, F.; Verga, L.; Frangione, B.; Farlow, M.R.; Bugiani, O.; and Ghetti, B.: Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease. Brain Research, 530:325-329, 1990.
Bugiani, O.; Giaccone, G.; Verga, L.; Pollo, B.; Ghetti, B.; Frangione, B.; and Tagliavini, F.: Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits. Neuroscience Letters, 119:56-59, 1990.
Kaseda, Y.; Ghetti, B.; Low, W.C.; Norton, J.; Brittain, H.; Richter, J.A.; and Simon, J.R.: Age-related changes in striatal dopamine D2 receptor binding in weaver mutant mice and effects of ventral mesencephalic grafts. Experimental Brain Research, 83:1-8, 1990.
Ghetti, B.; Triarhou, L.C.; Alyea, C.J.; Dlouhy, S.R.; and Karn, R.C.: Unique cerebellar phenotype combining granule and Purkinje cell loss: morphological evidence for weaver*pcd double mutant mice. Journal of Neurocytology, 20:27-38, 1991.
Tagliavini, F.; Prelli, F.; Ghiso, J.; Bugiani, O.; Serban, D.; Prusiner, S.B.; Farlow, M.R.; Ghetti, B.; and Frangione, B.: The amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11-Kd degradation product of PrP that starts at position 58 of the cDNA-deduced PrP sequence. EMBO Journal, 10:513-519, 1991.
Giaccone, G.; Tagliavini, F.; Verga, L.; Frangione, B.; Farlow, M.R.; Bugiani, O.; and Ghetti, B.: Indiana kindred of Gerstmann-Sträussler-Scheinker syndrome: neurofibrillary tangles and neurites of plaques with Prp amyloid share antigenic determinants with those of Alzheimer disease. IN: K. Iqbal, D.R.C. McLachlan, B. Winblad, H.M. Wisniewski (Eds.), Alzheimer's disease: basic mechanisms, diagnosis and therapeutic strategies, pp. 207-211, John Wiley and Sons Ltd., Chichester, England, 1991.
Bugiani, O.; Verga, L.; Tagliavini, F.; Pollo, B.; Ghetti, B.; Frangione, B.; Giaccone, G.: Synaptic alterations in preamyloid deposits. IN: K. Iqbal, D. R. C. McLachlan, B. Winblad, H. M. Wisniewski (Eds.), Alzheimer's disease: basic mechanisms, diagnosis and therapeutic strategies, pp. 329-331, John Wiley and Sons Ltd., Chichester, England, 1991.
Bugiani, O.; Constantinidis, J.; Ghetti, B.; Bouras, C.; and Tagliavini, F.: Asymmetric cerebral atrophy in Alzheimer's disease. Clinical Neuropathology, 10:55-60, 1991.
Triarhou, L.C.; and Ghetti, B.: Stabilisation of neurone number in the inferior olivary complex of aged "Purkinje cell degeneration" (pcd) mutant mice. Acta Neuropathologica (Berl), 81:597-602, 1991.
Ghetti, B.; Tagliavini, F.; Masters, C.L.; Beyreuther, K.; Giaccone, G.; Verga, L.; Farlow, M.R.; Conneally, P.M.; Dlouhy, S.R.; Azzarelli, B.; and Bugiani, O.: Gerstmann-Sträussler-Scheinker disease: II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family. Neurology, 39:1453-1461, 1989. IN: K. M. Brinkhous, F. G. Dalldorf, R. D. Langdell, W. W. McLendon (Eds.), Year Book of Pathology and Clinical Pathology, pp. 206-209, Mosby Year Book, St. Louis, MO, 1991.
Murrell, J.; Farlow, M.R.; Ghetti, B.; and Benson, M.D.: A mutation in the amyloid precursor protein (APP) associated with hereditary Alzheimer's disease. Science, 254:97-99, 1991.
Simon, J.R.; Yu, H.; Richter, J.A.; Vasko M.R.; and Ghetti, B.: In vitro release of endogenous dopamine from the striatum of the weaver mutant mouse. Journal of Neurochemistry, 57:1478-1482, 1991.
Farlow, M.R.; Tagliavini, F., Bugiani, O.; and Ghetti, B.: Gerstmann-Sträussler-Scheinker disease. IN: P.J. Vinken, G.W. Bruyn, H. L.Klawans (Eds.), J.M.B.V. de Jong (Co-Ed.), Handbook of Clinical Neurology, Vol. 16, pp. 619-633, Elsevier Science Publishers B.V., Amsterdam, The Netherlands, 1991.
Triarhou, L.C.; and Ghetti, B.: Serotonin immunoreactivity in the cerebellum of two neurological mutant mice and the corresponding wild type genetic stocks. Journal of Chemical Neuroanatomy, 4:421-428, 1991.
Wei, J.; Hofstetter, R.J.; Dlouhy, S.; Ghetti, B.; Nurnberger, J.Jr.; and Hodes, M.E.: Screening and isolating specific expressed mRNA from mouse cerebellum: subtractive hybridization. Chinese Journal of Genetics, 18:59-68, 1991.
Yee, R.D.; Farlow, M.R.; Suzuki, D.A.; Betelak, K.F.; and Ghetti, B.: Abnormal eye movements in Gerstmann-Sträussler-Scheinker disease. Archives of Ophthalmology, 110:68-74, 1992.
Ghetti, B.; Murrell, J.; Benson, M.D.; and Farlow, M.R.: Spectrum of amyloid ß-protein immunoreactivity in hereditary Alzheimer disease with a guanine to thymine missense change at position 1,924 of the APP gene. Brain Research, 571:133-139, 1992.
Ghetti, B.; and Triarhou, L.C.: Degeneration of mesencephalic dopamine neurons in weaver mutant mice. IN: P. Spano, G.N. Woodruff, G.L. Gessa (Eds.), Dopamine '90; Dopaminergic systems and their regulation. Proceedings of the Satellite Meeting of the XIth International Congress of Pharmacology. Como, Italy, July 8-11, 1990. Neurochemistry International, 20, Suppl., 305S-307S, 1992.
Dlouhy, S.R.; Hsiao, K.; Farlow, M.R.; Foroud, T.; Conneally, P.M.; Johnson, P.; Prusiner, S.B.; Hodes, M.E.; and Ghetti, B.: Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene. Nature Genetics, 1:64-67, 1992.
Hsiao, K.; Dlouhy, S.R.; Farlow, M.R.; Cass, C.; Da Costa, M.; Conneally, P.M.; Hodes, M.E.; Ghetti, B.; and Prusiner, S.B.: Mutant Prion Protein in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Nature Genetics, 1:68-71, 1992.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Intraparenchymal grafting of cerebellar cell suspensions to the deep cerebellar nuclei of pcd mutant mice, with particular emphasis on re-establishment of a Purkinje cell cortico-nuclear projection. Anatomy and Embryology, 185:409-420, 1992.
Simon, J.R.; and Ghetti, B.: Topographic distribution of dopamine uptake, choline uptake, cholineacetyltransferase and GABA uptake in the striata of the weaver mutant mouse. Neurochemical Research, 17:431-436, 1992.
Richter, J.A.; Stotz E.H.; Ghetti, B.; and Simon, J.R.: Comparison of alterations in tyrosine hydroxylase, dopamine levels and dopamine uptake in the striatum of the weaver mutant mouse. Neurochemical Research, 17:437-441, 1992.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Serotonin fiber innervation of cerebellar cell suspensions intraparenchimally grafted to the cerebellum of pcd mutant mice. Neurochemical Research, 17:475-482, 1992.
Ghetti, B.; and Triarhou, L.C.: The Purkinje cell degeneration mutant: a model to study the consequences of neuronal degeneration. IN: A. Plaitakis (Ed.), Cerebellar degenerations: clinical neurobiology, pp. 159-181, Kluwer Academic Publishers, Boston, Mass., 1992.
Farlow, M.R.; Ghetti, B.; Benson, M.D.; Farrow, J.S.; Van Nostrand, W.E.; and Wagner, S.L.: Low cerebrospinal-fluid concentrations of soluble amyloid ß-protein precursor in hereditary Alzheimer's disease. The Lancet, 340:453-454, 1992.
Giaccone, G.; Verga, L.; Bugiani, O.; Frangione, B.; Serban, D.; Prusiner, S.B.; Farlow, M.R.; Ghetti, B.; and Tagliavini, F.: Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Proceedings of the National Academy of Science, USA, 89:9349-9353, 1992.
Ghetti, B.; Bugiani, O.; Farlow, M.R.; and Bugiani, O.: La malattia di Gerstmann-Sträussler-Scheinker. IN: M. Carreras, C.A. Defanti, F. Cornelio, and A. Federico (Eds.), XI Corso di aggiornamento della Società Italiana di Neurologia, Bergamo, 20-23 ottobre 1992, pp. 337-349, Monduzzi Editore, Bologna, Italy, 1992.
Ghetti, B.; Tagliavini, F.; Hsiao, K.; Dlouhy, S.R.; Yee, R.; Giaccone, G.; Conneally, P.M.; Hodes, M.E.; Bugiani, O.; Prusiner, S.B.; Frangione B.; and Farlow, M.R.: Indiana variant of Gerstmann-Sträussler-Scheinker disease. IN: S.B. Prusiner, J. Collinge, B. Powell, and B. Anderton (Eds.), Prion diseases of human and animals, chapter 16, pp. 153-166, Ellis Horwood, London, 1992
Ghetti, B.; and Triarhou, L.C.: Combined degeneration of cerebellar granule cells and of midbrain dopamine neurons in the weaver mutant mouse. IN: F. Hefti and W.J. Weiner (Eds.), Progress in Parkinson's disease Research; Proceedings of the Second International Conference of the National Parkinson Foundation, chapter 23, pp. 375-388, Futura Publishing Co., Inc., Mount Kisko, N.Y., 1992.
Triarhou, L.C.; Low, W.C.; Doucet, G.; Brundin, P.; Björklund, A. and Ghetti, B.: The weaver mutant mouse as a model for intrastriatal grafting of fetal dopamine neurons. IN: F. Hefti and W.J. Weiner (Eds.), Progress in Parkinson's disease Research; Proceedings of the Second International Conference of the National Parkinson Foundation, chapter 24, pp. 389-400 Futura Publishing Co., Inc., Mount Kisko, N.Y., 1992.
Bugiani, O.; Giaccone, G.; Verga, L.; Pollo, B.; Frangione, B.; Farlow, M. R.; Tagliavini, F.; and Ghetti, B.: ß-PP participates in PrP-amyloid plaques of Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Journal of Neuropathology and Experimental Neurology, 52:64-70, 1993.
Ghetti, B.; Triarhou L.C.; and Fuller, R.W.: Cerebellar monoamines in the "Purkinje cell degeneration" mutant mouse. IN: P. Trouillas and K. Fuxe (Eds.), Serotonin, the cerebellum, and ataxia, chapter 22, pp. 297-306, Raven Press, Ltd., New York, N.Y., 1993.
Stotz, E.H.; Triarhou, L.C.; Ghetti, B.; and Simon, J.R.: Serotonin content is elevated in the dopamine deficient striatum of the weaver mutant mouse. Brain Research, 606:267-272, 1993.
Simon, J.R.; and Ghetti, B.: Is there a significant somatodendritic uptake of dopamine in the substantia nigra? Evidence from the weaver mutant mouse. Neurochemistry International, 22:471-477, 1993.
Solà, C.; Mengod, G.; Ghetti, B.; Palacios, J.M.; and Triarhou L.C.: Regional distribution of the alternatively spliced isoforms of ßAPP RNA transcript in the brain of normal, heterozygous and homozygous weaver mutant mice as revealed by in situ hybridization histochemistry. Molecular Brain Research, 17:340-346, 1993.
Ghetti, B.; Farlow, M.R.; Murrell, J.; and Benson, M.D.: Guanine to thymine missense change at codon 717 of the APP gene: further characterization of an Alzheimer phenotype. IN: B. Corain, K. Iqbal, M. Nicolini, B. Winblad, H.M. Wisniewski, P. Zatta (Eds.), Alzheimer's disease: advances in clinical and basic research, pp. 227-234, John Wiley and Sons Ltd., Chichester, England, 1993.
Kambouris, M.; Sangameswaran, L.; Dlouhy, S.R.; Hodes, M.E.; Ghetti, B.; and Triarhou L.C.: Cellular distribution of the RNA transcripts of a newly discovered gene in the brain of normal, weaver, Purkinje cell degeneration and reeler mutant mice as evidenced by in situ hybridization histochemistry. Molecular Brain Research, 18:321-328, 1993.
Zeldenrust, S.R.; Murrell, J.; Farlow, M.; Ghetti, B.; Roses, A.D.; and Benson, M.D.: RFLP Analysis for APP-717 mutations associated with Alzheimer's disease. Journal of Medical Genetics, 30:476-478, 1993.
Tagliavini, F.; Giaccone, G.; Prelli, F.; Verga, L.; Porro, M.; Trojanowski, J.Q.; Farlow, M.R.; Frangione, B.; Ghetti, B.; and Bugiani, O.: A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Brain Research, 616:325-328, 1993.
Solà, C.; Mengod, G.; Low, W.C.; Norton, J.; Ghetti, B.; Palacios, J.M. and Triarhou L.C.: Regional distribution of amyloid ß-protein precursor, growth-associated phosphoprotein-43 and microtubule associated protein 2 messenger RNAs in the nigrostriatal system of normal and weaver mutant mice and effects of ventral mesencephalic grafts. European Journal of Neuroscience, 5:1442-1454, 1993.
Tagliavini, F.; Prelli, F.; Verga, L.; Giaccone, G.; Sarma, R.; Gorevic, P.; Ghetti, B.; Passerini, F.; Ghibaudi, E.; Forloni, G; Salmona, M.; Bugiani, O.; and Frangione, B.: Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro. Proceedings of the National Academy of Science, USA, 90:9678-9682, 1993.
Liepnieks, J.J.; Ghetti, B.; Farlow, M.R.; Roses, A.D.; and Benson, M.D.: Characterization of amyloid fibril ß-peptide in familial Alzheimer's disease with APP 717 mutations. Biochemical and Biophysical Research Communications, 197:386-392, 1993.
Vogelweid, C.M.; Verina, T.; Norton, J.; Harruff, R.; and Ghetti, B.: Hypospermatogenesis is the cause of infertility in the male weaver mutant mouse. Journal of Neurogenetics, 9:89-104, 1993.
Richter, J.A.; Ghetti, B.; and Simon, J.: Dopamine-depleting effects of MPTP and Reserpine in weaver mutant mice. Molecular and Chemical Neuropathology, 20:219-228, 1993.
Chang A.C.; Ghetti, B: Embryonic cerebellar graft development during acute phase of gliosis in the cerebellum of pcd mutant mice. Chinese Jounal of Physiology, 36:141-149, 1993.
Simon, J.R.; Richter, J.A.; and Ghetti, B.: Age-dependent alterations in dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse. Journal of Neurochemistry, 62:543-548, 1994.
Farlow, M.R.; Murrell, J.; Ghetti, B.; Unverzagt, F.; Zeldenrust, S.; and Benson, M.D.: Clinical characteristics in a kindred with early onset Alzheimer's disease and their linkage to a G to T change at position 2149 of the amyloid-precursor protein gene. Neurology, 44:105-111, 1994.
Monari, L.; Chen, S.G.; Brown, P.; Parchi, P.; Petersen, R.B.; Nikol, J.; Gray, F.; Cortelli, P.; Montagna, P.; Ghetti, B.; Goldfarb, L.G.; Gajdusek, D.C.; Lugaresi, E.; Gambetti, P.; and Autilio-Gambetti, L.: Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Different prion proteins determined by a DNA polymorphism. Proceedings of the National Academy of Science, USA, 91:2839-2842, 1994.
Ghetti, B.; Tagliavini, F.; Giaccone, G.; Bugiani, O.; Frangione, B.; Farlow, M.R.; and Dlouhy, S.R.: Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Molecular Neurobiology, 8:41-48, 1994
Simon, J.; and Ghetti, B.: The weaver mutant mouse as a model of nigrostriatal dysfunction. Molecular Neurobiology, 9:183-189, 1994.
Farlow, M.R.; Ghetti, B.; Dlouhy, S.R.; Giaccone, G.; Bugiani, O.; Tagliavini, F.; and Wagner, S.: Cerebrospinal fluid levels of amyloid ß-protein precursor are low in Gerstmann-Sträussler-Scheinker, Indiana kindred. Neurology, 44:1508-1510, 1994.
Kambouris, M.; Ghetti, B.; Dlouhy, S. R.; Triarhou L.C.; Sangameswaran, L.; Luo, F.; and Hodes, M.E.: Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library. Molecular Brain Research, 25:183-191, 1994.
Kambouris, M.; Sangameswaran, L.; Triarhou L.C.; Kozak, C.; Dlouhy, S.R.; Ghetti, B.; and Hodes, M.E.: Molecular characterization of a novel cDNA from murine cerebellum, developmental expression, and distribution in brain. Molecular Brain Research, 25:192-199, 1994.
Stotz, E.H.; Palacios, J.M.; Landwehrmeyer, B.; Norton, J.; Ghetti, B.; Simon, J.R.; and Triarhou, L.C.: Alterations in dopamine and serotonin uptake systems in the striatum of the weaver mutant mouse. Journal of Neural Transmission, 97:51-64, 1994.
Bayer, S.A.; Triarhou, L.C.; Thomas, J.D.; and Ghetti, B.: Correlated quantitative studies of the neostriatum, nucleus accumbens, substantia nigra, and ventral tegmental area in normal and weaver mutant mice, Journal of Neuroscience, 14:6901-6910, 1994.
Triarhou, L.C.; Stotz, E.H.; Low, W.C.; Norton, J.; Ghetti, B.; Landwehrmeyer, B.; Palacios, J.M.; and Simon, J.R.: Studies on the striatal dopamine uptake system of weaver mutant mice and effects of ventral mesencephalic grafts. Neurochemical Research, 19:1349-1358, 1994.
Hodes, M.E.; Dlouhy, S.R.; Wei, J.J.; Wang, Y.; Sangameswaran, L.; Lazar, V.; Triarhou, L.C.; and Ghetti, B.: cDNA approaches to isolation of the mouse mutant weaver gene. Neurochemical Research, 19:1359-1362, 1994.
Wei, J.; Dlouhy, S.R.; Zhu, J; Ghetti, B.; and Hodes, M.E.: Analysis of region-specific library constructed by sequence-independent amplification of microdissected fragments surrounding weaver (wv) gene on mouse chromosome 16. Somatic Cell and Molecular Genetics, 20:401-408, 1994.
Tagliavini, F.; Prelli, F.; Porro, M.; Rossi, G.; Giaccone, G.; Farlow, M.R.; Dlouhy, S.R.; Ghetti, B.; Bugiani, O.; and Frangione, B.: Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish Kindreds) express only PrP peptides encoded by the mutant allele. Cell, 79:695-703, 1994.
Verina, T.; Tang, X.; Fitzpatrick, L.; Norton, J.; Vogelweid, C.; and Ghetti, B.: Degeneration of Sertoli and spermatogenic cells in homozygous and heterozygous weaver mice. Journal of Neurogenetics, 9:251-265, 1995.
Triarhou, L.C.; Solà, C.; Mengod G.; Low, W.C.; Garcia-Ladona F.J.; Ghetti, B.; Landwehrmeyer, B.; Ghetti, B.; and Palacios, J.M.: Ventral mesencephalic grafts in the neostriatum of the weaver mutant mouse: structural molecule and receptor studies. Cell Transplantation,4:39-48, 1995.
Richter, J.A.; Bare, D.J.; Yu, H; Ghetti, B.; and Simon, J.R.: Dopamine transporter-dependent and independent endogenous dopamine release from weaver mouse striatum in vitro. Journal of Neurochemistry, 64:191-198, 1995.
Ghetti, B.; Dlouhy, S.R.; Giaccone, G.; Bugiani, O.; Frangione, B.; Farlow, M.R.; and Tagliavini, F.: Gerstmann-Sträussler-Scheinker disease and the Indiana Kindred. Brain Pathology, 5:61-75, 1995
Suzuki, K.; Parker, C.C.; Pentchev, P.G.; Katz, D.; Ghetti B.; D'Agostino, A.N.; and Carstea, E.D.: Neurofibrillary tangles in Niemann-Pick disease type C. Acta Neuropathologica, 89:227-238, 1995
Richter, J.A.; Brenneman, M.G.; Dlouhy, S.R.; and Ghetti, B.: Dopaminergic parameters in the striatum and substantia nigra of seven strains of mice: higher density in striatum of cast compared to BALB mice. Neurochemical Research, 20:395-400, 1995
Young, K.; Jones, C.K.; Piccardo, P.; Lazzarini, A.; Golbe, L.I.; Zimmerman, T.R.; Dickson, D.W.; Vinters, H.; Hodes, M.E.; Dlouhy, S.; and Ghetti, B.: Gerstmann-Sträussler-Scheinker disease with mutation at codon 102 and methionine at codon 129 of the PRNP in previously unreported patients. Neurology, 45:1127-1134, 1995
Lee, W-H.; Wang, G-M.; Lo, T.; Triarhou, L.C.; and Ghetti, B.: Altered IGFBP5 gene expression in the cerebellar external germinal layer of weaver mutant mice. Molecular Brain Research, 30:259-268, 1995.
Stotz-Potter, B. Ghetti, B.; and Simon, J.R.: Endogenous serotonin release from the dopamine deficient striatum of the weaver mutant mouse. Neurochemical Research, 20:821-826, 1995.
Bayer, S.A.; Wills, K.V.; Triarhou, L.C.; and Ghetti B.: Time of neuron origin and gradients of neurogenesis in the mouse midbrain dopaminergic neurons. Experimental Brain Research, 105:191-199, 1995.
Bayer, S.A.; Wills, K.V.; Triarhou, L.C.; Thomas, J.D.; and Ghetti B.: Systematic differences in time of midbrain dopaminergic neuron origin between normal mice and homozygous weaver mutants. Experimental Brain Research, 105:200-208, 1995.
Bayer, S.A.; Wills, K.V.; Triarhou, L.C.; Verina, T.; Thomas, J.D.; and Ghetti B.: Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice. Proceedings of the National Academy of Sciences, USA 92:9237-9140, 1995.
Bare, D.J.; Ghetti, B.; and Richter, J.A.: The tyrosine kinase inhibitor genistein increases endogenous dopamine release from normal and weaver mutant mouse striatal slices. Journal of Neurochemistry, 65:2096-2104, 1995.
Migheli, A.; Attanasio, A.; Lee, W.-H.; Bayer, S.A.; and Ghetti, B.: Detection of apoptosis in weaver cerebellum by electron microscopic in situ end-labeling of fragmented DNA. Neuroscience Letters, 199:53-56, 1995.
Piccardo, P.; Ghetti, B.; Dickson, D.W.; Vinters, H.V.; Giaccone, G.; Bugiani, O.; Tagliavini, F.; Young, K.; Dlouhy, S.R.; Seiler, C.; Jones, C.; Lazzarini, A.; Golbe, L.I.; Zimmerman, T.R.; Perlman, S.L.; McLachlan, D.C.; St George-Hyslop, P.H.; and Lennox, A.: Gerstmann-Sträussler-Scheinker disease (P102L): amyloid deposits are best recognized by antibodies directed to epitopes in PrP region 90-165. Journal of Neuropathology and Experimental Neurology, 54:790-801, 1995.
Ghetti, B.; Piccardo, P.; Spillantini, M.G.; Ichimiya, Y.; Porro, M.; Perini, F.; Kitamoto, T.; Tateishi, T.; Seiler, C.; Frangione, B.; Bugiani, O.; Giaccone, G.; Prelli, F.; Goedert, M.; Dlouhy, S.R.; and Tagliavini, F.: Vascular Variant of Prion Protein Cerebral Amyloidosis with τ-Positive Neurofibrillary Tangles: The Phenotype of the Stop Codon 145 Mutation in PRNP. Proceedings of the National Academy of Sciences, USA 93:744-748, 1996.
Lippa, C.F.; Saunders, A.; Smith, T.W.; Swearer, J.M.; Drachman, D.A.; Ghetti, B.; Nee, L.; Pulaski-Salo, D.; Dickson, D.; Robitaille, Y.; Bergeron, C.; Crain, B.; Benson, M.D.; Farlow, M.; Hyman, B.T.; St. George-Hyslop, P.; Roses, A.D.; and Pollen, D.A.: Familial and sporadic Alzheimer's disease: Neuropathology cannot exclude a final common pathway. Neurology, 46:406-412, 1996.
Ghetti, B.; Piccardo, P.; Frangione, B.; Bugiani, O.; Giaccone, G.; Young, K.; Prelli, F.; Farlow, M.R.; Dlouhy, S.R.; and Tagliavini, F.: Prion protein amyloidosis. Brain Pathology, 6:127-145, 1996.
Wei, J.; Dlouhy, S.R.; Hara, A.; Ghetti, B.; and Hodes, M.E.: Cloning a cDNA for carbonyl reductase (Cbr) from mouse cerebellum: murine genes that express Cbr map to chromosomes 16 and 11. Genomics, 34:147-148, 1996.
Tagliavini, F.; Prelli, F.; Giaccone, G.; Forloni, G.; Salmona, M.; Piccardo, P.; Ghetti, B.; Frangione, B.; and Bugiani, O.: Methods for studying prion protein amyloids. IN: H.F. Baker and R.M. Ridley (Eds.), Methods in Molecular Medicine: Prion Diseases, pp. 265-284, Humana Press, Totowa, N.J. 1996.
Parchi, P.; Castellani, R.; Capellari, S.; Petersen, R.B.; Young, K.; Chen, S.G.; Dickson, D.W.; Sima, A.A.F.; Trojanowski, J.Q.; Farlow, M.; Ghetti, B.; and Gambetti, P.: Molecular basis of phenotypic variability in sporadic Creutzeldt-Jakob disease: A novel classification. Annals of Neurology, 39:767-778, 1996.
Ghetti, B.; Piccardo, P.; Frangione, B.; Bugiani, O.; Giaccone, G.; Young, K.; Prelli, F.; Farlow, M.R.; Dlouhy, S.R.; and Tagliavini, F.: Prion Protein Hereditary Amyloidosis: Parenchymal and Vascular. Seminars in Virology, 7:189-200, 1996.
Perini, F.; Vidal, R.; Ghetti, B.; Tagliavini, F.; Frangione, B.; and Prelli, F.: Soluble PrP 27-30 is a normal prion protein fragment released by platelets. Biochemical and Biophysical Research Communications, 223:572-577, 1996.
Tong, Y.; Wei, J.; Zhang, S.; Strong, J.A.; Dlouhy, S.R.; Hodes, M.E.; Ghetti, B.; and Yu, L.: The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2. FEBS Letters, 390:63-68, 1996.
Wei, J.; Hodes, M.E.; Wang, Y.; Feng, Y.; Ghetti, B.; and Dlouhy, S.R.: Direct cDNA selection with DNA microdissected from mouse chromosome 16: Isolation of novel clones and construction of a partial transcription map of the C3-C4 region. Genome Research, 6:678-687, 1996.
Wei, J.; Dlouhy, S.R.; Zhu, J.; Wang, Y.; Fitzpatrick, L.; Ghetti, B.; and Hodes, M.E.: Linkage mapping of microdissected clones from distal mouse chromosome 16. Somatic Cell and Molecular Genetics, 22:227-232, 1996.
Bayer, S.A.; Wills, K.V.; Wei, J.; Feng, Y.; Dlouhy, S.; Hodes, M.E.; Verina, T.; and Ghetti B.: Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain. Developmental Brain Research, 96:130-137, 1996.
Piccardo, P.; Seiler, C.; Dlouhy, S.R.; Young, K.; Farlow, M.R.; Prelli, F.; Frangione, B.; Bugiani, O.; Tagliavini, F.; and Ghetti, B.: Protease K resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker Disease (Indiana kindred). Journal of Neuropathology and Experimental Neurology, 55:1157-1163, 1996.
Tagliavini, F.; Prelli, F.; Salmona, M.; Ghetti, B.; Giaccone, G.; Bugiani, O.; Frangione, B.; and Forloni, G.: Chemicophysical properties and biological activities of synthetic prion protein (PrP) peptides and their relationship to human cerebral PrP amyloidosis. IN: L. Court and B. Dodet (Eds.), Transmission Subacute Spongiform Encephalopathies: Prion Diseases, Elsevier, Paris, 323-327, 1996.
Cervenakova, L.; Brown, P.; Piccardo, P.; Cummings, J.L.; Nagle, J.; Vinters, H.V.; Kaur, P.; Ghetti, B.; Chapman, J.; Gajdusek, D.C.; Goldfarb, L.G.: 24-Nucleotide deletion in the PRNP gene: Analysis of associated phenotypes. IN: L. Court and B. Dodet (Eds.), Transmission Subacute Spongiform Encephalopathies: Prion Diseases, Elsevier, Paris, 433-444, 1996.
Verina, T.; Norton, J.; Sorbel, J.; Triarhou, L.; Richter, J.; Laferty, D.; and Ghetti, B.: Atrophy and loss of dopaminergic mesencephalic neurons in heterozygous weaver mice. Experimental Brain Research, 113:5-12, 1997.
Unverzagt, F.W.; Farlow, M.R.; Norton, J.; Dlouhy, S.R.; Young, K.; and Ghetti, B.: Neuropsychological function in patients with Gerstmann-Sträussler-Scheinker disease from the Indiana Kindred (F198S). Journal of the International Neuropsychological Society, 3:169-178, 1997.
Zhang, W.; Ghetti, B.; and Lee, W-H.: Decreased IGF-I gene expression during the apoptosis of Purkinje cells in the pcd mice. Developmental Brain Research, 98:164-176, 1997.
Young, K.; Clark, H.B.; Piccardo, P.; Dlouhy, S.R.; and Ghetti, B.: Gerstmann-Sträussler-Scheinker disease with the PRNP P102L mutation and valine at codon 129. Molecular Brain Research, 44:147-150, 1997.
Young, K.; Clark, H.B.; Piccardo, P.; Dlouhy, S.R.; and Ghetti, B.: Phenotypic variants of P102L Gerstmann-Sträussler-Scheinker disease. IN: K. Iqbal, B. Winblad, T. Nishimura, M. Takeda, H. M. Wisniewski, (Eds.), Alzheimer's disease: Biology, Diagnosis and Therapeutics, pp. 125-130, John Wiley and Sons Ltd., Chichester, England, 1997.
Spillantini, M.G.; Goedert, M.; Crowther, R.A.; Murrell, J.R.; Farlow, M.R.; and Ghetti, B.: Characterization of familial multiple system tauopathy with presenile dementia. IN: K. Iqbal, B. Winblad, T. Nishimura, M. Takeda, H.M. Wisniewski, (Eds.), Alzheimer's disease: Biology, Diagnosis and Therapeutics, pp. 213-223, John Wiley and Sons Ltd., Chichester, England, 1997.
Tagliavini, F.; Prelli, F.; Salmona, M.; Giaccone, G.; Ghetti, B.; Bugiani, O.; Frangione, B.; and Forloni, G.: PrP peptides and pathogenesis of prion diseases. IN: K. Iqbal, B. Winblad, T. Nishimura, M. Takeda, H.M. Wisniewski, (Eds.), Alzheimer's disease: Biology, Diagnosis and Therapeutics, pp. 491-495, John Wiley and Sons Ltd., Chichester, England, 1997.
Park, D.; Boldt, H.C.; Massicotte, S.J.; Akang E.E.U.; Roos, K.L.; Bodnar, A.; Pless, J.; Ghetti, B.; and Pascuzzi, R.M.: Subacute sclerosing pan-encephalitis manifesting as viral retinitis: Clinical and histopathologic findings. American Journal of Ophthalmology, 123:533-542, 1997.
Simon, J.R.; Bare, D.J.; Ghetti, B.; and Richter, J.A.: A possible role for tyrosine kinase in the regulation of the neuronal dopamine transporter in mouse striatum. Neuroscience Letters, 224:201-205, 1997.
Spillantini, M.G.; Goedert, M.; Crowther, R.A.; Murrell, J.R.; Farlow, M.R.; and Ghetti, B: Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proceedings of the National Academy of Science, USA 94:4113-4118, 1997.
Won, L.; Ghetti, B.; Heller, B.; and Heller, A.: In vitro evidence that the reduction in mesencephalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction. Experimental Brain Research, 115:174-179, 1997.
Ghetti, B.; Tagliavini, F.; Dlouhy, S.R.; Piccardo, P.; Young, K.; Yee, R.D.; Hutchins, G.D.; Giaccone, G.; Prelli, F.; Frangione, B.; Unverzagt, F.; Bugiani, O.; and Farlow, M.R.: The natural history of Gerstmann-Sträussler-Scheinker disease in the Indiana kindred. In: Rossi, A. and Annunziata, P. (Eds.), Libro Giubilare: Professor Gian Carlo Guazzi, Università di Siena, Pp 315-331, 1997.
Ghetti, B.; Piccardo, P.; Frangione, B.; Bugiani, O.; Giaccone, G.; Young, K.; Prelli, F.; Farlow, M.R.; Dlouhy, S.R.; and Tagliavini F: Hereditary Prion Protein Amyloidosis. IN: Encefalopatias Espongiformes En Animales Y En El Hombre. Seminario International, Series 22, Academia National de Agronomia y Veterinaria, pp 57-63, Buenos Aires, Argentina, 1996.
Piccardo, P.; Seiler, C.; Dlouhy, S.R.; Young, K.; Farlow, M.R.; Prelli, F.; Frangione, B.; Bugiani, O.; Tagliavini F,; and Ghetti, B.: Prion protein isoforms in PrP gene (PRNP) mutation F198S. IN: Encefalopatias Espongiformes En Animales Y En El Hombre. Seminario International, Series 22, Academia National de Agronomia y Veterinaria, pp 64-69, Buenos Aires, Argentina, 1996
Wei, J.; Dlouhy, S.R.; Bayer, S.; Piva, R.; Verina, T.; Wang, Y.; Feng, Y.; Hodes, M.E.; Dupree, B.; and Ghetti, B.: In situ hybridization analysis of Girk2 expression in the developing CNS in normal and weaver mice. Journal of Neuropathology and Experimental Neurology, 56:762-771, 1997.
Foster, N.L.; Wilhelmsen, K.; Sima, A.A.F.; Jones, M.Z.; D'Amato, C.; and Gilman, S.: Participants of the Chromosome 17-Related Dementia Conference: Frontotemporal dementia and Parkinsonism linked to chromosome 17: A consensus. Annals of Neurology, 41:706-715, 1997
Bales, K.R.; Verina, T.; Dodel, R.C.; Du Y.; Altstiel, L.; Bender, M.; Hyslop, P.; Johnstone, E.M.; Little, S.P.; Cummins, D.J.; Piccardo, P.; Ghetti, B.; and Paul, S.M.: Lack of apolipoprotein E dramatically reduces amyloid ß-peptide deposition. Nature Genetics, 17:263-264, 1997.
Migheli, A.; Piva, R.; Wei, J.; Attanasio, A.; Casolino, S.; Hodes, M.E.; Dlouhy, S.R.; Bayer, S.; and Ghetti, B.: Diverse cell death pathways result from a single missense mutation in weaver mouse. American Journal of Pathology, 151:1629-1638, 1997.
Murrell, J.R.; Koller, D.; Foroud, T.; Goedert, M.; Spillantini, M.G.; Edenberg, H.J.; Farlow, M.R.; and Ghetti, B.: Familial multiple-system tauopathy with presenile dementia localized to chromosome 17. American Journal of Human Genetics, 61:1131-1138, 1997.
Mayeux, R.; Saunders, A.M.; Shea, S.; Mirra, S.; Evans, D.; Roses, A.D.; Hyman, B.; Crain, B.; Tang, M-X.; Phelps, C.H.; and Alzheimer's Disease Centers Consortium on APOE and Alzheimer's Disease: Utility of the APOE genotype in the diagnosis of Alzheimer's disease. New England Journal of Medicine, 338:506-511, 1998.
Brown, P.; Cervenakova, L.; McShane, L.; Goldfarb, L.G.; Bishop, K.; Bastian, F.; Kirkpatrick, J.; Piccardo, P.; Ghetti, B.; and Gajdusek, D.C.: Creutzfeldt-Jakob disease in a husband and wife. Neurology, 50:684-688, 1998.
Spillantini, M.G.; Bird, T.D.; and Ghetti, B.: Frontotemporal dementia and Parkinsonism linked to chromosome 17: A new group of tauopathies. Brain Pathology, 8:387-402, 1998.
Ghetti, B.; Tagliavini, F.; Dlouhy, S.R.; Piccardo, P.; Young, K.; Yee, R.D.; Hutchins, G.D.; Giaccone, G.; Prelli, F.; Frangione, B.; Unverzagt, F.; Bugiani, O.; and Farlow, M.R.: Clinical, pathological, and molecular characterization of Gerstmann-Sträussler-Scheinker disease in the Indiana Kindred (PRNP F198S). In: Morrison, D.R.O. (Ed.), Prions and Brain Diseases in Animals and Humans, Pp 269-278, 1998.
Tagliavini, F.; Giaccone, G.; Prelli, F.; Frangione, B.; Salmona, M.; Forloni, G.; Ghetti, B.; and Bugiani, O.: PrP peptides as a tool to investigate the pathogenesis of prion protein amyloidosis. In: Morrison, D.R.O. (Ed.), Prions and Brain Diseases in Animals and Humans, Pp 285-289, 1998.
Parchi, P.; Gambetti, P.; Piccardo, P.; and Ghetti, B.: Human Prion Diseases. In: Kirkham, N. and Lemoine, N.R. (Eds.), Progress in Pathology, Chapter 3, Vol 4, Pp 39-77, Churchill Livingstone, Edinburgh, U.K., 1998.
Piccardo, P.; Langeveld, J.P.M.; Hill, A.F.; Dlouhy, S.R.; Young, K.; Wells, G.A.H.; Giaccone, G.; Rossi, G.; Bugiani, M.; Bugiani, O.; Meloen, R.H.; Collinge, J.; Tagliavini, F.; and Ghetti, B.: An antibody raised against a conserved sequence of the prion protein recognizes pathologic isoforms in human and animal prion diseases, including vCJD and BSE. American Journal of Pathology, 152:1415-1420, 1998.
Spillantini, M.G.; Murrell, J.R.; Goedert, M.; Farlow, M.R.; Klug, A.; and Ghetti, B.: Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proceedings of the National Academy of Science, USA 95:7737-7741, 1998.
Ghetti, B.; Piccardo, P.; Frangione, B.; Bugiani, O.; Giaccone, G.; Young, K.; Prelli, F.; Farlow, M. R.; Dlouhy, S.R.; and Tagliavini, F.: Phenotypic heterogeneity of hereditary prion protein amyloidoses. In: Goebel, K. (Ed.), International Seminar on Nuclear War and Planetary Emergencies, 22^nd Session, Pp. 66-84, 1998.
Wei, J.; Hodes, M.E.; Piva, R.; Feng, Y.; Wang, Y.; Ghetti, B.; and Dlouhy, S.R.: Characterization of murine Girk2 transcript isoforms: structure and differential expression. Genomics, 51:379-390, 1998.
Piccardo, P.; Dlouhy, S.R.; Lievens, P.M.J.; Young, K.; Bird, T.D.; Nochlin, D.; Dickson, D.W.; Vinters, H.V.; Zimmerman, T.R.; Mackenzie, I.R.A.; Kish, S.J.; Ang, L-C.; De Carli, C.; Pocchiari, M.; Brown, P.; Gibbs, C.J.; Gajdusek, D.C.; Bugiani, O.; Ironside, J.; Tagliavini, F.; and Ghetti, B.: Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity. Journal of Neuropathology and Experimental Neurology, 57:979-988, 1998.
Lippa, C.F.; Fujiwara, H.; Mann, D.M.A.; Giasson, B.; Baba, M.; Schmidt, M.L.; Nee, L.E.; O'Connell, B.; Pollen, D.A.; St. George-Hyslop, P.; Ghetti, B.; Nochlin, D.; Bird, T.D.; Cairns, N.J.; Lee, V.M.-Y.; Iwatsubo, T.; and Trojanowski, J.Q.: Lewy bodies contain altered a-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. American Journal of Pathology, 153:1365-1370, 1998.
Jimenez-Heute, A.; Lievens, P.M.J.; Vidal, R.; Piccardo, P.; Ghetti, B.; Tagliavini, F.; Frangione, B.; and Prelli, F.: Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. American Journal of Pathology, 153:1561-1572, 1998.
Fox, A.P.; Dlouhy, S.; Ghetti, B.; Hurley, J.H.; Nucifora, P.G.; Nelson, D.J.; Won, L.; and Heller, A.: Altered responses to potassium in cerebellar neurons from weaver heterozygote mice. Experimental Brain Research, 123:298-306, 1998.
Schwartz, N.B.; Szabo, M.; Verina, T.; Wei, J.J.; Dlouhy, S.R.; Won, L.; Heller, A.; Hodes, M.E.; and Ghetti, B.: Hypothalamic-pituitary-gonadal axis in the mutant weaver mouse. Neuroendocrinology, 68:374-385, 1998.
Salanova, M.; Markand, O.; Worth, R.; Smith, R.; Wellman, H.; Hutchins, G.; Park, H. M.; Ghetti, B.; and Azzarelli, B.: FED-PET and volumetric MRI in temporal lobe epilepsy (TLE) relationship to febrile seizures and hippocampal sclerosis. Acta Neuropathological Scandinavica, 98:146-153, 1998.
Chiesa, R.; Piccardo, P.; Ghetti, B.; and Harris, D.A.: Neurological illness in transgenic mice expressing a prion protein with an insertional mutation. Neuron, 21:1339-1351, 1998.
Tagliavini, F.; Salmona, M.; Forloni, G.; Malesani, P.; Giaccone, G.; Canciani, B.; McArthur, R.; Lansen, J.; Piccardo, P.; Dlouhy, S.R.; Ghetti, B.; Frangione, B.; Prelli, F.; and Bugiani, O.: Prion diseases: PrP peptides, pathogenesis and treatment perspectives. In: Harris, D.A. (Ed.), Prions: Molecular and Cellular Biology, Horizon Scientific Press, Norfolk, U.K, pp 125-138, 1999.
Young, K.; Piccardo, P.; Dlouhy, S.; Bugiani, O.; Tagliavini, F.; and Ghetti, B.: The Human Genetic Prion Diseases. In: Harris, D.A. (Ed.), Prions: Molecular and Cellular Biology, Horizon Scientific Press, Norfolk, U.K., pp 139-175, 1999.
Piccardo, P.; Langeveld, J.P.M.; Hill, A.F.; Dlouhy, S.R.; Young, K.; Giaccone, G.; Rossi, G.; Bugiani, M.; Bugiani, O.; Meloen, R.H.; Collinge, J.; Tagliavini, F.; and Ghetti, B.: An antibody recognizing prion protein residues 100-108 detects pathologic isoforms in human and animal prion diseases. In: SAGPya (Ed.), Proceeding 2^nd meeting of the Argentine Scientific Advisory Committee on Bovine Spongiform Encephalopathy. SENASA, pp 34-37, 1998.
Goedert, M.; Crowther, R.A.; Jakes, R.; Hasegawa, M.; Smith, M.J.; Murrell, J.R.; Ghetti, B.; and Spillantini, M.G.: Filamentous tau protein and -synuclein deposits in neurodegenerative diseases. IN: K. Iqbal, D.F. Swaab, B. Winblad, H.M. Wisniewski, (Eds.), Alzheimer's Disease and Related Disorders: Etiology, Pathogenesis and Therapeutics, John Wiley and Sons Ltd., Chichester, England, pp 245-258, 1999.
Chiesa, R.; Piccardo, P.; Ghetti, B.; and Harris, D A.: A transgenic mouse model of a familial prion disease with an insertional mutation. IN: K. Iqbal, D.F. Swaab, B. Winblad, H.M. Wisniewski, (Eds.), Alzheimer's Disease and Related Disorders: Etiology, Pathogenesis and Therapeutics, John Wiley and Sons Ltd., Chichester, England, pp 569-280, 1999.
Mirra, S.S.; Murrell, J.R.; Gearing, M.; Spillantini, M.G.; Goedert, M.; Crowther, R.A.; Levey, A.I.; Jones, R.; Green, J.; Shoffner, J.M.; Wainer, B.H.; Schmidt, M.L.; Trojanowski, J.Q.; and Ghetti, B.: Tau pathology in a family with dementia and a P301L mutation in tau. Journal of Neuropathology and Experimental Neurology, 58:335-345, 1999.
Bugiani, O.; Murrell, J.R.; Giaccone, G.; Hasegawa, M.; Ghigo, G.; Tabaton, M.; Morbin, M.; Primavera, A.; Carella, F.; Solaro, C.; Grisoli, M.; Savoiardo, M.; Spillantini, M.G.; Tagliavini, F.; Goedert, M.; and Ghetti, B.: Frontotemporal dementia and corticobasal degeneration in a family with a Pro301Ser mutation in tau. Journal of Neuropathology and Experimental Neurology, 58:667-677, 1999.
Delisle, M-B.; Murrell, J.; Richardson, R.; Trofatter, J.A.; Rascol, O.; Soulages, X.; Mohr, M.; Calvas, P.; and Ghetti, B.: A mutation at codon 279 (N279K) in exon 10 of the tau gene causes a tauopathy with dementia and supranuclear palsy. Acta Neuropathologica, 98:62-77, 1999.
Varani, L.; Hasegawa, M.; Spillantini, M.G.; Smith, M.J.; Murrell, J.R.; Ghetti, B.; Klug, A.; Goedert, M. and Varani, G.: Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proceedings of the National Academy of Science, USA, 96:8229-8234, 1999.
Gambetti, P.; Petersen, R.B.; Parchi, P.; Chen, S.G.; Capellari, S.; Goldfarb, L.; Gabizon, R.; Montagna, P.; Lugaresi, E.; Piccardo, P.; and Ghetti, B.: Inherited Prion Diseases. IN: Prion Biology and Diseases, Cold Spring Harbor Laboratory Press, NY. Pp 509-583, 1999.
Parchi, P.; Giese, A.; Capellari, S.; Brown, P.; Schulz-Schaefer, W.; Windl, O.; Zerr, I.; Budka, H.; Kopp, N.; Piccardo, P.; Poser, S.; Rojiani, A.; Streichemberger, N.; Julien, J.; Vital, C.; Ghetti, B.; Gambetti, P.; and Kretzschmar, H.: Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Annals of Neurology, 46:224-233, 1999.
Migheli A.; Piva, R.; Casolino, S.; Atzori, C.; Dlouhy, S.R.; and Ghetti, B.: A cell cycle alteration precedes apoptosis of granule cell precursors in the weaver mouse cerebellum. American Journal of Pathology, 155:365-373, 1999.
Ghetti, B; Giaccone, G; Piccardo, P.; Dlouhy, S.R.; Bugiani, O.; and Tagliavini, F.: Human hereditary prion protein amyloidosis. IN: Kyle, R. A. and Gertz, M.A. (Eds.), Amyloid and Amyloidosis. Proceedings of the VIII International Symposium on Amyloidosis, Parthenon Publishing. Pp 459-463, 1999.
Piccardo, P.; Dlouhy, S.R.; Lievens, P.M.J.; Bugiani, O.; Tagliavini, F.; and Ghetti, B.: Prion protein heterogeneity in Gerstmann-Sträussler-Scheinker P102L. IN: Kyle, R. A. and Gertz, M.A. (Eds.), Amyloid and Amyloidosis. Proceedings of the VIII International Symposium on Amyloidosis, Parthenon Publishing. Pp 464-466, 1999.
Ghetti, B.; Spillantini, M.G.; Murrell, J.; Crowther, R.A.; Farlow, M.R.; and Goedert, M.: Hereditary multiple system tauopathies with dementia. In: R. Ragaini (Ed.), International Seminar on Nuclear War and Planetary Emergencies, 23^rd Session, Pp. 40-45, 1999.
Ghetti, B.; and Gambetti, P.: Human Prion Diseases. In Mattson, M. P. (Ed.), Advances in Cell Aging and Gerontology, Volume 3: Genetic Aberrancies and Neurodegenerative Disorders, Chapter 5, Jai Press Inc., Greenwich, CT. pp 135-187, 1999.
Broome, J.D.; Wills, K.V.; Lapchak, P.A.; Ghetti, B.; Camp, L.L.; and Bayer, S.A.: Glial cell line-derived neurotrophic factor protects midbrain dopamine neurons from the lethal action of the weaver gene: a quantitative immunocytochemical study. Developmental Brain Research, 116:1-7, 1999.
Ghetti, B.; Murrell, J.R.; and Spillantini, M.G.: Mutations in the Tau gene cause frontotemporal dementia. Brain Research Bulletin, 50:471-472, 1999.
Zhang, W.; Ghetti, B.; Yang, X.L.and Lee, W-H.: Alteration of IGF system gene expression during the postnatal development of pcd mice. Journal of Endocrinology, 163:191-198, 1999.
Murrell, J.R.; Spillantini, M.G.; Zolo, P.; Guazzelli, M.; Smith, M.J.; Hasegawa, M.; Redi, F.; Crowther, R.A.; Pietrini, P.; Ghetti, B.; and Goedert, M.: Tau gene mutation G389R causes a tauopathy with abundant Pick body-like inclusions and axonal deposits. Journal Neuropathology Experimental Neurology, 58:1207-1226, 1999.
Bales, K.R.; Verina, T.; Cummins, D.J.; Du, Y.; Dodel, R.C.; Saura, J.; Fishman, C.E.; DeLong, C.A.; Piccardo, P.; Ghetti, B.; Paul, S.M.: Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer's disease. Proceedings of the National Academy of Science, USA, 96:15233-15238, 1999.
Ghetti, B.; Murrell, J.; Zolo, P.; Spillantini, M.G.; and Goedert, M.: Progress in hereditary tauopathies: a mutation in tau gene (G389R) causes a Pick disease-like syndrome. In: J.H. Growdon, R.J. Wurtman, S. Corkin, R.M. Nitsch (Eds), Molecular Genetics of Dementia, Proceedings of the Nineth Meeting of the International Study Group on the Pharmacology of Memory Disorders Associated with Aging, Zurich, Switzerland, pp 65-77, 2000.
Goedert, M.; Ghetti, B.; and Spillantini, M.G.: Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP–17): Their relevance for understanding the neurodegenerative process. Proceedings of the Nineth Meeting of the International Study Group on the Pharmacology of Memory Disorders Associated with Aging, Zurich, Switzerland, pp 91-101, 2000.
Ghetti, B.; Piccardo, P.: Prion Protein Amyloidoses. In: Grateau, G.; Benson, M.D.; Delpech, M.: (Eds.), Les Amyloses. Medecine-Sciences Flammarion, Paris France. pp 523-545, 2000.
Harkins, A.B.; Dlouhy, S.; Ghetti, B.; Won, L.; Heller, B.; Heller, A. and Fox, A.P.: Elevated intracellular calcium levels may lead to neuronal cell death in weaver homozygote mice. Journal of Physiology, 524:447-455, 2000.
Chiesa, R.; Drisaldi, B.; Quaglio, E.; Migheli, A.; Piccardo, P.; Ghetti, B.; Harris, D.A.: Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a prion protein insertional mutation. Proceedings of the National Academy of Science, USA, 97:5874-5579, 2000.
Vidal, R.; Calero, M.; Piccardo, P.; Farlow, M.R.; Unverzagt, F.W.; Mendez, E.; Jimenez-Huete, A.; Beavis, R.; Gomez-Tortosa, E.; Ghiso, J.; Hyman, B.T.; Frangione, B.; Ghetti, B.: Senile dementia associated with Aß angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-4 allele. Acta Neuropathologica, 100:1-12, 2000.
Murrell, J.R.; Hake, A.M; Quaid, K.A.; Farlow, M.R.; Ghetti, B.: Early onset Alzheimer disease caused by a new mutation (V717L) in the APP gene. Archives of Neurology, 57:885-7, 2000.
Russo, C.; Schettini, G.; Saido, T.C.; Hulette, C.; Lippa, C.; Lannfelt, L.; Ghetti, B.; Gambetti, P.; Tabaton, M.; and Teller, J.K.: Presenilin 1 mutations in Alzheimer’s disease. Nature, 404:531-532, 2000.
Bugiani, O.; Giaccone, G.; Piccardo, P.; Morbin, M.; Tagliavini, F.; and Ghetti, B.: Neuropathology of Gerstmann-Sträussler-Scheinker disease. Microscopy Research and Technique, 50:10-15, 2000.
Parchi, P.; Zou, W.; Wang, W.; Brown, P.; Capellari, S.; Ghetti, B.; Kopp, N.; Schulz-Schaeffer, W.J.; Kretzschmar, H.A.; Head, M.W.; Ironside, J.W.; Gambetti, P.; and Chen, S.G.: Genetic influence on the structural variations of the abnormal prion protein. Proceedings of the National Academy of Science, USA, 97:10168-100072, 2000.
Ghetti, B.; Murrell, J.R.; Zolo, P.; Spillantini, M.G.; and Goedert, M.: Progress in hereditary tauopathies: A new mutation in tau gene (G389R) causes a Pick disease-like syndrome. IN: J.H. Growdon, R.J. Wurtman, S. Corkin, and R.M. Nitsch (Eds.) The Molecular Basis of Dementia. Annals of the New York Academy of Science 920:52-62, 2000.
Goedert, G.; Ghetti, B.; and Spillantini, M.G.: Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurodegenerative process. IN: J.H. Growdon, R.J. Wurtman, S. Corkin, and R.M. Nitsch (Eds.) The Molecular Basis of Dementia. Annals of the New York Academy of Science, 920:74-83, 2000.
Martí-Clua, J.; Wills, K.V.; Ghetti, B.; and Bayer S.A.: The weaver gene has no effect on the generation patterns of mesencephalic dopaminergic neurons. Developmental Brain Research, 122:165-172, 2000.
Martí-Clua, J.; Wills, K.V.; Ghetti, B.; and Bayer S.A.: The weaver gene continues to target late-generated dopaminergic neurons in the midbrain areas at P90. Developmental Brain Research, 122:173-181, 2000.
Harris, D.A.; Chiesa, R.; Drisaldi, B.; Quaglio, E.; Migheli, A.; Piccardo, P.; and Ghetti, B.: A transgenic model of a familial prion disease. Archives of Virology, Suppl. 16:103-112, 2000.
Takao, M.; Benson, M.D.; Murrell, J.R.; Yazaki, M.; Piccardo, P.; Unverzagt, F.W.; Davis, R.L.; Holohan, P.D.; Lawrence, D.A.; Richardson, R.; Farlow, M.R.; and Ghetti, B.: Neuroserpin mutation S52R causes neuroserpin accumulation in neurons and is associated with progressive myoclonus epilepsy. Journal of Neuropathology and Experimental Neurology, 59:1070-1086, 2000.
Lippa, C.F.; Swearer, J.M.; Kane, K.J.; Nochlin, D.; Bird, T.D.; Ghetti, B.; Nee, L.E.; Pollen, D.A.; and Brachman, D.A.: Familial Alzheimer’s disease: site of mutation influences clinical phenotype. Annals of Neurology, 48:376-379, 2000.
Delisle, M.B.; Uro-Coste, E.; Murrell, J.R.; Rascol, O.; and Ghetti, B.: Neurodegenerative disease associated withi a mutation of codon 279 (N279K) in exon 10 of tau protein. Bulletin de la Académie Nationale de Médecine, 184:799-809, 2000.
Quaid, K.A.; Murrell, J.R.; Hake, A.M.; Farlow, M.R.; and Ghetti, B. Early onset Alzheimer disease: counseling and predictive testing in a sibship. Journal of Genetic Counseling, 9:327-341, 2000.
Ghetti, B.; Murrell, J.R.; Spillantini, M.G.; Zolo, P.; Redi, F.; Guazzelli, M.; Smith, M.J. Hasegawa, M.; Crowther, R.A.; Pietrini, P.; and Goedert M.: Progress in hereditary tauopathies: a new mutaiton in the Tau gene (G389R) causes a Pick disease-like syndrome. IN: R. Ragaini (Ed.), International Seminar on Nuclear War and Planetary Emergencies, 24^th Session, Pp. 135-151, 2000.
Ghetti, B.; Piccardo, P.; Frangione, R.; Vidal, R.; and Ghiso, J.: Neuropathology and genetics of prion protein and British cerebral amyloid angiopathies. IN: M.M. Verbeek, R.M.W. de Waal and H.V. Vinters (Ed.) Cerebrovascular amyloidosis (CAA) in Alzheimer’s Disease and Related Disorders. 237-247, 2000.
Levy, E.; Sastre, M.; Kumar, A.; Gallo, G.; Piccardo, P.; Ghetti, B.; and Tagliavini, F.: Codeposition of cystatin C with amyloid-ß protein in the brain of Alzheimer's disease patients. Journal of Neuropathology and Experimental Neurology, 60:94-104, 2001.
Yazaki, M.; Liepnieks, J.J.; Murrell, J.R.; Takao, M.; Guenther, B.; Piccardo, P.; Farlow, M.R.; Ghetti, B.; and Benson, M.D.: Biochemical characterization of a neuroserpin variant associated with hereditary dementia. American Journal of Pathology, 158:227-233, 2001.
Tagliavini, F.; Lievens, P.M.; Tranchant, C.; Warter, J.M.; Mohr, M.; Giaccone, G.; Perini, F.; Rossi, G.; Salmona, M.; Piccardo, P.; Ghetti, B.; Beavis, R.C.; Bugiani, O.; Frangione, B.; and Prelli, F.: A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Straussler-Scheinker disease A117V. Journal of Biological Chemistry, 276:6009-6015, 2001.
Harris, D.A.; Chiesa, R.; Migheli, A.; Piccardo, P.; and Ghetti, B.: Cellular and transgenic models of familial prion diseases. IN: H.F. Baker (Ed.) Molecular Pathology of the Prions, Humana Press, Totowa. 2001.
Chiesa, R.; Pestronk, A.; Schmidt, R.E.; Tourtellotte, W.G.; Ghetti, B.; Piccardo, P.; and Harris, D.A.: Primary myopathy and accumulation of prp(sc)-like molecules in peripheral tissues of transgenic mice expressing a prion protein insertional mutation. Neurobiology of Disease. 8:279-88, 2001.
Farlow, M.R..; Murrell, J.R.; Unverzagt, F.W.; Phillips, M.; Takao, M.; Hulette, C.; and Ghetti, B. Familial Alzheimer’s Disease with Spastic Paraparesis Associated with a Mutation at Codon 261 of the Presenilin 1 Gene. . IN: K. Iqbal, S.S.Sisodia, B. Winblad, (Eds.), Alzheimer’s Disease: Advances in Etiology, Pathogenesis and Therapeutics, John Wiley and Sons Ltd., Chichester, England,pp 53-60, 2001.
Piccardo P.; Liepnieks J.J.; William A.; Dlouhy S.R.; Farlow M.R.; Young K.; Nochlin D.; Bird T.D.; Nixon R.R.; Ball M.J.; DeCarli C.; Bugiani O.; Tagliavini F.; Benson M.D.; and Ghetti B.: Prion proteins with different conformations accumulate in Gerstmann-Sträussler-Scheinker disease caused by A117V and F198S mutations. American Journal of Pathology, 158: 2201-2207, 2001.
Russo, C.; Schettini, G.; Saido, T.C.; Hulette, C.; Lippa, C.; Lannfelt, L.; Ghetti, B.; Gambetti, P.; Tabaton, M.; and Teller, J.K.: Molecular consequences of presenilin-1 mutations (reply). Nature 411:655, 2001.
Ringman, J.M.; Jain, V.; Murrell, J.; Ghetti, B.; and Cochran, E.J.: Human Gene Mutations: Gene Symbol: PSEN1, Disease: Alzheimer disease. Human Genetics, 109:242, 2001.
Marti, J.; Wills, K.V.; Ghetti, B.; and Bayer, S.A.: Evidence that the loss of Purkinje cells and deep cerebellar nuclei neurons in homozygous weaver is not related to neurogenetic patterns. International Journal of Developmental Neuroscience, 19:599-610, 2001.
Panegyres, P.K.; Toufexis, K.; Kakulas, B.A.; Brown, P.; Ghetti, B.; Piccardo, P.; and Douhy, S.R.: A new mutation [G131V] linked to Gerstmann-Sträussler-Scheinker disease. Archives of Neurology, 58:1899-1902, 2001.
Cataldo, A.; Rebeck, G.W.; Ghetti, B.; Hulette, C.; Lippa, C.; Van Broeckhoven, C.; Van Duijn, C.; Cras, P.; Bogdanovic, N.; Bird, T.; Peterhoff, C.; and Nixon, R.: Endocytic disturbances distinguish among subtypes of Alzheimer’s disease and related disorders. Annals of Neurology, 50:661-665, 2001.
Takao, M.; Ghetti, B.; Murrell, J.R.; Unverzagt, F.W.; Giaccone, G.; Tagliavini, F.; Bugiani, O.; Piccardo, P.; Hulette, C.; Crain, B.J.; Farlow, M.R.; and Heyman, A.: Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures. Journal of Neuropathology and Experimental Neurology, 60:1137-1152, 2001.
Atzori, C.; Ghetti, B.; Piva, R.; Srinivasan, A.N.; Zolo, P.; Delisle, M.B.; Mirra S.S.; and Migheli, A.: Activation of JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. Journal of Neuropathology and Experimental Neurology, 60:1190-1197, 2001.
Taratuto, A.L.; Piccardo, P.; Reich, E.G.; Chen, S.G.; Sevlever, G.; Schultz, M.; Luzzi, A.A.; Rugiero, M.; Abecasis, G.; Endelman, M.; Garcia, A.M.; Capellari, S.; Xie, Z.; Lugaresi, E.; Gambetti, P.; Dlouhy, S.R.; and Ghetti, B.: Insomnia associated with thalamic involvement in E200K Creutzfeldt-Jakob disease. Neurology, 58:362-367, 2002.
Marti, J.; Wills, K.V.; Ghetti, B.; and Bayer, S.A. Regional differences in the purkinje cells settled pattern: a comparative autoradiographic study in control and homozygous weaver mice. Experimental Neurology, 175:168-181, 2002.
Moehlmann, T.; Winkler, E.; Xuefeng, X.; Edbauer, D.; Murrell, J.; Capell, A.; Kaether, C.; Zheng, H.; Ghetti, B.; Haass, C.; and Steiner, H.: Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on A42 production. Proceedings of the National Academy of Science, U.S.A, 99:8025-8030, 2002.
Tsuboi, Y.; Uitti, R.J.; Delisle, M-B.; Ferreira, J.J.; Brefel-Courbon, C.; Rascol, O.; Ghetti, B.; Murrell, J.R.; Hutton, M.; Baker, M.; and Wszolek Z.K.: Clinical features and disease haplotypes of individuals with the N279K Tau gene mutation: A comparison of the Pallidopontonigral degeneration kindred and a French family. Archives of Neurology, 59:943-950, 2002.
Takao, M.; Ghetti, B.; Hayakawa, I.; Ikeda, E.; Fukuuchi, Y.; Miravalle, L.; Piccardo, P.; Murrell, J.R.; Glazier, B.S.; and Koto, A.: A novel mutation (G217D) in the Presenilin 1 gene (PSEN1) in a Japanese family: presenile dementia and parkinsonism are associated with cotton wool plaques in the cortex and striatum. Acta Neuropathol (Berl), 104:155-70, 2002.
Marti, J.; Wills, K.U.; Ghetti, B.; and Bayer, S.A.: A combined immunohistochemical and autoradiographic method to detect midbrain dopaminergic neurons and determine their time of origin. Brain Research Protocols, 9:197-205, 2002.
Davis, R.L.; Shrimpton, A.E., Carrell, R.W.; Lomas, D.A.; Gerhard, L.; Baumann, B.; Lawrence, D.A.; Yepes, M.; Kim, T.S.; Ghetti, B.; Piccardo, P.; Takao, M.; Lacbawan, F.; Muenke, M.; Sifers, R.N.; Bradshaw, C.B.; Kent, P.F.; Collins, G.H.; Larocca, D.; and Holohan, P.D.: Association between conformational mutations in neuroserpin and onset and severity of dementia. The Lancet, 359:2242-2247, 2002.
Adamec, E.; Murrell, J.R.; Takao, M.; Hobbs, W.; Nixon, R.A.; Ghetti, B.; and Vonsattel, J.P.: P301L tauopathy. Confocal immunofluorescence study of perinuclear aggregation of the mutated protein. Journal of the Neurological Sciences, 200:85-93, 2002.
Zhong, J.; Deng, J.; Ghetti, B.; and Lee, W.H.: Inhibition of insulin-like growth factor I’s activity contributes to the premature apoptosis of cerebellar granule neuron in weaver mutant mice: an in vitro analysis. Journal of Neuroscience Research, 70:36-45, 2002.
Ogunniyi, A.; Akang, E.E.U.; Gureje, O.; Takao, M.; Piccardo, P.; Baiyewu, O.; Hall, K.S.; Ghetti, B.; and Hendrie, H.C.: Dementia with Lewy bodies in a Nigerian: A case report. International Psychogeriatrics, 14:211-218, 2002.
Piccardo, P.; Ghetti, B.; Tagliavini, F.; and Bugiani, O.: Structural Variations of abnormal prion protein in Gerstmann-Sträussler-Scheinker disease. IN: R. Ragaini (Ed.), International Seminar on Nuclear War and Planetary Emergencies, 26^th Session, Pp. 457-465, 2002.
Allen, B.; Ingram, E.; Takao, M.; Smith, M.J.; Jakes, R.; Virdee, K.; Yoshida, H.; Holzer, M.; Craxton, M.; Emson, P.C.; Atzori, C.; Migheli, A.; Crowther, R.A.; Ghetti, B.; Spillantini, M.G.; and Goedert, M.: Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. Journal of Neuroscience, 9340-9351, 2002.
Tsuboi, Y.; Baker, M.; Hutton, M.L.; Uitti, R.J.; Rascol, O.; Delisle, M.B.; Soulages, X.; Murrell, J.R.; Ghetti, B.; Yasuda, M.; Komure, O.; Kuno, S.; Arima, K.; Sunohara, N.; Kobayashi, T.; Mizuno, Y.; and Wszolek, Z.K.: Clinical and genetic studies of families with the tau N279K mutation (FTDP-17). Neurology, 59:1791-1793, 2002.
Vidal, R.; Delisle, M.B.; Rascol, O.; and Ghetti, B.: Hereditary Ferritinopathy. Journal of the Neurological Sciences, 207:110-111, 2003.
Ghetti, B.; Tagliavini, F.; Takao, M.; Bugiani, O.; and Piccardo, P.: Hereditary Prion Protein Amyloidoses. IN: B. Ghetti, P. Piccardo (Eds.), Clinics in Laboratory Medicine: Prion Diseases. Elsevier Science (USA), Philadelphia, PA, pp. 65-85, 2003.
Harris, D.A.; Chiesa, R.; Drisaldi, B.; Quaglio, E.; Migheli, A.; Piccardo, P.; and Ghetti, B.: A Murine Model of a Familial Prion Disease. IN: B. Ghetti, P. Piccardo (Eds.), Clinics in Laboratory Medicine: Prion Diseases. Elsevier Science (USA), Philadelphia, PA, pp. 175-186, 2003.
Ghetti, B.; Takao, M.; Yazaki, M.; Farlow, M.R.; Unverzagt, F.W.; Piccardo, P.; Murrell, J.R.; and Benson, M.D. Neuropathology at the crossroad of neuropsychiatry and genetics: new insights into neuroserpin encephalopathy. IN: R. Ragaini (Ed.), International Seminar on Nuclear War and Planetary Emergencies, 27^th Session, Pp. 550-567, 2003.
Ghetti, B.; Tagliavini, F.; Bugiani, O.; and Piccardo, P.: Gerstmann-Sträussler-Scheinker disease. IN: D. Dickson (Ed.) Neurodegeneration. The Molecular Pathology of Dementia and Movement Disorders, ISN Neuropath Press, Basesl, Pp. 318-325., 2003.
Ghetti, B.; Hutton, M.; and Wszolek, Z.K.: Frontotemporal dementia and Parkinsonism linked to chromosome 17 associated with Tau gene mutations (FTDP-17T). IN: D. Dickson (Ed.) Neurodegeneration. The Molecular Pathology of Dementia and Movement Disorders, ISN Neuropath Press, Basel, Pp. 86-102, 2003.
Chiesa, R.; Piccardo, P.; Quaglio, E.; Drisaldi, B.; Si-Hoe, S.L.; Takao, M.; Ghetti, B.; and Harris, B.A.: Molecular distinction between pathogenic and infectious properties of the prion protein. Journal of Virology, 77:7611-7622., 2003.
Powers, J.M.; Byrne, N.P.; Ito, M.; Takao, M.;, Yankopoulou, D.; Spillantini, M.G.; and Ghetti, B.: A novel leukoencephalopathy associated with tau deposits in white matter glia. Acta Neuropathologica, 106:181-187, 2003.
Tofaris, G.K.; Razzaq, A.; Ghetti, B.; Lilley, K.S.; and Spillantini, M.G.: Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function. Journal of Biological Chemistry, 2003 278:44405-44411.
De Michele, G.; Pocchiari, M.; Petraroli, R.; Manfredi, M.; Caneve, G.; Coppola, G.; Casali, C.; Sacca, F.; Piccardo, P.; Salvatore, E.; Berardelli, A.; Orio, M.; Barbieri, F.; Ghetti, B.; and Filla, A.: Variable phenotype in a P102L Gerstmann-Sträussler-Scheinker Italian family. Canadian Journal of Neurological Sciences, 30:233-236, 2003.
Roher, A.E.; Kokjohn, T.A.; Esh, C.; Weiss, N.; Childress, J.; Kalback, W.; Luehrs, D.C.; Lopez, J.; Brune, D.; Kuo, Y.M.; Farlow, M.; Murrel,l J.; Vidal, R.; and Ghetti, B.: The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates. Journal of Biological Chemistry, 279:5829-5836, 2004.
Notari, S.; Capellari, S.; Giese, A.; Westner, I.; Baruzzi, A.; Ghetti, B.; Gambetti, P.; Kretzschmar, H.A.; and Parchi, P.: Effects of different experimental conditions on the PrPSc core generated by protease digestion: Implications for strain typing and molecular classification of CJD. Journal of Biological Chemistry, 279:16797-16804, 2004.
Kong Q,; Surewicz W.K.; Petersen R.B.; Zou W.; Chen S.G.; Gambetti P.: Inherited Prion Diseases. In: Prusiner SB (ed), Prion Biology and Disease, 2^nd edition, Chapter 14, Pp 673-776. Cold Spring Harbor Laboratory Press, 2004.
Vitali, A.; Piccini, A.; Borghi, R.; Fornaro, P.; Siedlak, S.L.; Smith, M.A.; Gambetti, P.; Ghetti, B.; and Tabaton, M.: Soluble amyloid beta-protein is increased in frontotemporal dementia with tau gene mutations. Journal of Alzheimers Disease, 6:45-51, 2004.
Vidal, R.; Ghetti, B.; Takao, M.; Brefel-Courbon, C.; Uro-Coste E.; Glazier, B.S.; Siani, V.; Benson, M.D.; Calvas, P.; Miravalle, L.; Rascol, O.; and Delisle, M.B.: Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the Ferritin Light Polypeptide gene. Journal of Neuropathology and Experimental Neurology, 63:363-380, 2004.
Takao, M.; Ghetti, B.; Yoshida, H.; Piccardo, P.; Narain, Y.; Murrell J.R.; Vidal, R.; Glazier, B.S.; Jakes, R.; Tsutsui, M.; Spillantini, M.G.; Crowther, R.A.; Goedert, M.; and Koto, A.: Early-onset dementia with Lewy bodies. Brain Pathology, 14:137-147, 2004.
Vidal, R.; Delisle, M.B.; and Ghetti, B.: Neurodegeneration caused by proteins with an aberrant carboxyl-terminus. Journal of Neuropathology and Experimental Neurology. 63:787-800, 2004.
Barmada, S.; Piccardo, P.; Yamaguchi, K.; Ghetti, B.; and Harris, D.A.: GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice. Neurobiology of Disease, 16:527-37, 2004.
Woodruff, B.K.; Baba, Y.; Hutton, M.L.; Wszolek, Z.K.; Tsuboi, Y.; Kobayashi, T.; Ghetti, B.; Arima K.; Yasuda, M.; and Rascol, O.: Haplotype-phenotype correlations in kindreds with the N279K mutation in the tau gene. Archives of Neurology. 61:1327, 2004.
Takao, M.; and Ghetti, B.: Alzheimer's disease asscoiated with cotton wool plaques. Shinkei Kenkyu no Shinpo 48:451-466, 2004.
Chiesa, R.; Piccardo, P.; Dossena, S.; Nowoslawski, L.; Roth, K.A.; Ghetti, B.; and Harris, D.A.: Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease. Proceedings of the National Academy of Science, USA 102:238-243, 2005.
Boeve, B.; Tremont-Lukats, I.W.; Waclawik, A.J.; Murrell, J.R.; Hermann, B.; Jack, C.R.; Shiung, M.M.; Smith G.E.; Knopman, D.S.; Nair, A.R.; Lindor, N.; Koppikar, V.; and Ghetti, B.: Longitudinal Characterization of Two Siblings with frontotemporal dementia associated with the S305N Tau mutation. Brain 128:752-772, 2005.
Stewart, R.S.; Piccardo, P.; Ghetti, B.; and Harris, D.A.: Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein. Journal of Neuroscience. 25:3469-77, 2005.
Gemignani, A.; Pietrini, P.; Murrell, J.R.; Glazier, B.S.; Zolo, P.; Guazzelli, M.; and Ghetti, B. Slow wave and REM sleep mechanisms are differently altered in hereditary Pick disease associated with the Tau G389R mutation. Archives Italiennes de Biologie. 143:65-79, 2005.
Zaidi, S.I.; Richardson, S.L., Capellari, S.; Song, L.; Smith, M.A., Ghetti, B.; Sy, M.S.; Gambetti, P.; and Petersen, R.B.: Characterization of the F198S prion protein mutation: Enhanced glycosylation and defective refolding. Journal of Alzheimer’s Disease, 7:159-171, 2005.
Baba, Y.; Baker, M.C.; Uitti, R. J.; Hutton, M.L.; Dickson, D. W.; Farrer, M.; Putzke, J.D.; Woodruff, B. K.; Ghetti, B.; Murrell, J. R.; Boeve, B. F.; Petersen, R. C.; Verpillat, P.; Brice, A.; Delisle, M.B.; Rascol, O.; Arima, K.; Dysken, M. W.; Yasunda, M. Kobayashi, T.; Sunohara, N.; Komure, O.; Kuno, S.; Sperfeld, A. D.; Stoppe, G.; Kohlhase, J.; Pickering-Brown, S.; Neary, B.; Bugiani, O.; and Wszolek, Z.K.: The effect of tau genotype on clinical features in FTDP-17. Parkinsonism and Related Disorders. 11:205-208, 2005.
Ghetti, B.; Piccardo, P.; Bugiani, O.; Forloni, G.; Morbin, M.; Salmona, M.; and Tagliavini, F.: Hereditary prion protein amyloidoses. IN: D. R. Brown (Ed), Neurodegeneration and Prion Diseases, Springer, Chapter 4, Pg 83-109, 2005.
Ghetti, B.; Miravalle, L.; Yamaguchi, K.; Epperson, F.; Murrell, .J.R.; Perkins, T.; Hui, S.; Glazier, B.S.; Farlow, M.R.; Piccardo, P.; Dlouhy, S.: Role of the polymorhpism at codon 129 of the Prion Protein gene in the phenotypic expression of Gerstmann-Sträussler-Scheinker disease associated with the F198S mutation. IN: R. Ragaini (Ed.), International Seminar on Nuclear War and Planetary Emergencies, 32^nd Session, Pp. 133-136, 2005.
Yamaguchi, K.; Cochran, E.J.; Murrell, J.R.; Polymeropoulos, M.H.; Shannon, K.M.; Crowther, R.A.; Goedert, M.; and Ghetti, B.: Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the α-synuclein gene. Acta Neuropathologica 110:298-305, 2005.
Ringman, J.M.; Diaz-Olavarrieta, C.; Rodriguez, Y.; Chavez, M.; Fairbanks, L.;Paz, F.; Varpetian, A; Chaparro Maldonado, A; Macias-Islas, M.A.; Murrell, J.; Ghetti, B.; and Kawas, C.H.: Neuropsychological function in non-demented carriers of Presenilin 1 mutations. Neurology 65:552-558, 2005.
Miravalle, L.; Calero, M.; Takao, M.; Roher, A.E.; Ghetti, B.; and Vidal, R.: Amino-terminally truncated Aβ peptide species are the main component of cotton wool plaques. Biochemistry. 44:10810-21, 2005.
Petersen, R.B.; Siedlak, S. L.; Lee, H-G.; Kim, Y-S.; Nunomura, A.; Tagliavini, F.; Ghetti, B.; Cras, P.; Moreira P. I.; Castellani, R. J.; Guentchey, M.; Budka, H.; Ironside, J. W.; Gambetti, P.; Smith, M. A.; and Perry, G.: Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathologica 110:232-238. 2005.
Esh, C.; Patton, L.; Kalback, W.; Kokjohn, T.A.; Lopez, J.; Brune, D.; Newell, A.; Beach, T.; Schenk, D.; Games, D.; Paul, S.; Bales, K.; Ghetti, B.; Castano, E.; Roher, A.E.: Altered APP processing in PDAPP (Val717-Phe) transgenic mice yields extended-length Aβ peptides. Biochemistry 44:13807-19, 2005.
Castellani R.J.; Siedlak, S.L.; Fortino A.E; Perry, G.; Ghetti, B.; Smith, M.A.. Chitin-like polysaccharides in Alzheimer’s disease brains. Current Alzheimer Research 2:419-23, 2005.
Delobel, P.; Lavenir, I.; Ghetti, B.; Holzer, M.: Goedert, M.: Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. American Journal of Pathology 168:878-87, 2006.
Baba, Y.; Ghetti, B.; Baker, M. C.; Uitti, R. J.; Hutton, M. L.; Yamaguchi, K.; Bird, T.; Lin, W.; DeLucia, M. W.; Dickson, D. W.; and Wszolek, Z. K.: Hereditary diffuse leukoencephalopathy with spheroids: clinical, pathologic and genetic studies of a new kindred. Acta Neuropathologica 111:300-311, 2006.
Tofaris, G.K.; Garcia-Reitbock, P.; Humby, T.; Lambourne, S.L. O’Connell, M.; Ghetti, B.; Gossage, H.; Emson, P.C., Wilkinson, L.S.; Goedert, M.; Spillantini, M.G.: Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein (1-120): implications for Lewy body disorders. Journal of Neuroscience 26:3942-3950, 2006.
Ringman, J.M.; Rodriguez, Y.; Diaz-Olavarrieta, C.; Chavez, M.; Thompson, M.; Fairbanks, L.; Paz, F.; Varpetian, A.; Chaparro, H.; Macias-Islas, M.A.; Murrell, J.; Ghetti, B.; Kawas, C.: Performance on MMSE sub-items and education level in presenilin-1 mutation carriers without dementia. International Psychogeriatrics 29:1-10, 2006.
Colucci ,M.; Moleres, F.J.; Xie, Z.L.; Ray-Chaudhury, A.; Gutti, S.; Butefisch, C.M.; Cervenakova, L.; Wang, W.; Goldfarb, L.G.; Kong, Q.; Ghetti, B.; Chen S.G.; Gambetti P.: Gerstmann-Straussler-Scheinker: a new phenotype with 'curly' PrP deposits. Journal of Neuropathology and Experimental Neurology 65:642-51, 2006.
Shiarli, A.M.; Jennings, R.; Shi, J.; Bailey, K.; Davidson, Y.; Tian, J.; Bigio, E.H.; Ghetti, B.; Murrell, J.R.; Delisle, M-B.; Mirra, S.; Crain, B.; Zolo, P.; Arima, K.; Iseki, E.; Murayama, S.; Kretzchmar, H.; Neumann, M.; Lippa, C.; Halliday, G.; Mackenzie, J.; Khan, N.; Ravid, R.; Wszolek, Z.; Iwatsubo, T.; Pickering-Brown, S.M.; Mann, D.M.: Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer’s disease. Neuropathology and Applied Neurobiology 32:374-87, 2006.
Moroncini, G.; Mangieri, M.; Morbin, M.; Mazzoleni, G.; Ghetti, B.; Gabrielli, A.; Williamson, R.A.; Giaccone, G.; and Tagliavini, F.: Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody. Neurobiology of Disease 23:717-24.
Schweitzer, K.; Decker, E.; Zhu, L.; Miller, R.E.; Mirra, S.S.; Spina, S.; Ghetti, B.; Wang, M.; and Murrell, J.R. Aberrantly regulated proteins in frontotemporal dementia. Biochemistry and Biophysics Research Communication 22:465-72, 2006.
Murrell, J.R.; Ghetti, B.; Cochran, E.; Macias-Islas, M.A.; Medina, L.; Varpetian, A.; Cummings, J.L.; Mendez, M.F.; Kawas, C.; Chui, H.; and Ringman, J.M.: The A431E Mutation in PSEN1 causing familial Alzheimer’s disease originating in Jalisco state, Mexico: An additional fourteen families. Neurogenetics 7:277-9, 2006.
Wszolek Z.K.; Tsuboi Y.; Ghetti B.; Pickering-Brown S.; Baba Y.; Cheshire W.P.: Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Orphanet Journal of Rare Disease 9:30, 2006
Radde, R.; Bolmont, T.; Kaeser, S.A.; Coomaraswamy, J.; Lindau, D.; Stoltze, L.; Calhoun, M.E.; Jaggi, F.; Wolburg, H.; Gengler, S.; Haass, C.; Ghetti, B.; Czech, C.; Holscher, C.; Mathews, P.M.; and Jucker, M.: Aβ-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep 7:940-6, 2006.
Spillantini, M.G.; Murrell, J.R.; Goedert, M.; Farlow, M.; Klug, A.; and Ghetti, B.: Mutations in the Tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia. Journal of Alzehimer’s Disease 9:373-80, 2006.
Ghetti, B.; and Goebel, H.H.: Frontotemporal dementia: the post-tau era. Neurology 67:560-1, 2006.
Huey, E.D.; Grafman, J.; Wassermann, E.M.; Pietrini, P.; Tierney, M.C.; Ghetti, B.; Spina, S.; Baker, M.; Hutton, M.; Elder, J.W.; Berger, S.L.; Heflin, K.A.; Hardy, J.; and Momeni, P. Characteristics of frontotemporal dementia patients with a Progranulin mutation. Annals of Neurology 60:374-80, 2006.
Ghetti, B.: Neurodegeneration and Hereditary Dementias: 40 Years of Learning. Journal of Alzheimer’s Disease 9:45-52, 2006.
Ghetti, B.; Spina, S.; Hutton, M.; Wszoleck, Z.K.: Demenza frontotemporale e parkinsonismo con linkage al cromosoma 17 e mutazioni del gene Tau (FTDP-17T). In: G.L. Mancardi, F. Tagliavini, G. Vita, (eds.) Trattato di Neuropatologia. Torino: Contatto & Archimedica Editori, 625-661, 2006.
Ghetti, B. Bugiani, O.; Spina, S.; Tagliavini, F.; Piccardo, P.: Malattia di Gerstmann-Sträussler- Scheinker. In: G.L. Mancardi, F. Tagliavini, G. Vita, eds. Trattato di Neuropatologia. Torino: Contatto & Archimedica Editori, 663-683, 2006.
Goedert, M.; Spillantini, M.G.; Ghetti, B.; Crowther, R.A.; and Klug, A.: The Alzheimer tangle – 100 years on. In: M. Jucker, K. Beyreuther, C. Haass, R. Nitsch, Y. Christen, (eds.) Alzheimer: 100 years and beyond. Springer-Verlag, Berlin Germany, 2006.
Spina, S.; Murrell, J.R.; Yoshida, H.; Ghetti, B.; Bermingham, N.; Sweeney, B.; Dlouhy, S.R.; Crowther, R.A.; Goedert, M.; Keohane, C.: The novel Tau mutation G335S: clinical, neuropathological and molecular characterization. Acta Neuropathologica 113:461-470. Epub December 22, 2006.
Spina, S.; Murrell, J.R.; Huey, E.D.; Wassermann, E.; Pietrini, P.; Baraibar, M.A.; Barbeito, A.G.; Troncoso, J.C.; Vidal, R.; Ghetti, B.; Grafman, J. Clinicopathological features of frontotemporal dementia with Progranulin sequence variation. Neurology 68:820-827. Epub January 3, 2007.
Di Fede G.; Giaccone G.; Limido L.; Mangieri M.; Suardi S.; Puoti G.; Morbin M.; Mazzoleni G.; Ghetti B.; Tagliavini F. The epsilon isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Straussler-Scheinker disease. J Neuropathol Exp Neurol 66:124-30, 2007.
Baba Y.; Baker M.C.; Le Ber I.; Brice A.; Maeck L.; Kohlhase J.; Yasuda M.; Stoppe G.; Bugiani O.; Sperfeld A.D.; Tsuboi Y.; Uitti R.J.; Farrer M.J.; Ghetti B.; Hutton M.L.; Wszolek Z.K. Clinical and genetic features of families with frontotemporal dementia and parkinsonism linked to chromosome 17 with a P301S tau mutation. J Neural Transm. Epub February 23, 2007.
Piccardo P.; Manson J.C.; King D.; Ghetti B.; Barron RM. Accumulation of prion protein in the brain that is not associated with transmissible disease. Proc Natl Acad Sci U S A. 104:4712-7 Epub March 6, 2007.
Ghetti B.; Goedert M. SYMPOSIUM: Tau Protein and Neurodegeneration. Brain Pathology 17:56.
Goedert, M.; Ghetti, B.: Alois Alzheimer: His Life and Times. Brain Pathology 17:57-62, 2007.
Piccini, A.; Zanusso, G.; Borghi, R.; Noviello, C.; Monaco, S.; Russo, R.; Damonte, G.; Armirotti, A.: Gelati, M.; Giordano, R.; Zambenedetti, P.; Russo, C.; Ghetti, B.; and Tabaton, M. A presenilin 1 S170F mutation is associated with a novel Alzheimer’s disease molecular phenotype. Archives of Neurology 64:738-745, 2007.
Li A.; Piccardo P.; Barmada S.J.; Ghetti B.; Harris D.A. Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice. EMBO J. 26:2777-85. Epub May 17, 2007.
Marti J, Santa-Cruz MC, Bayer SA, Ghetti B, Hervas JP. Generation and survival of midbrain dopaminergic neurons in weaver mice. Int J Dev Neurosci. 2007 Aug;25(5):299-307. Epub 2007 May 17.
Ingelsson M, Ramasamy K, Russ C, Freeman SH, Orne J, Raju S, Matsui T, Growdon JH, Frosch MP, Ghetti B, Brown RH, Irizarry MC, Hyman BT. Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains. Acta Neuropathol 2007 Aug 25; Epub.
Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, Wood EM, Yu CE, Josephs K, Sorenson E, Womack KB, Weintraub S, Pickering-Brown SM, Schofield PR, Brooks WS, Van Deerlin VM, Snowden J, Clark CM, Kertesz A, Boylan K, Ghetti B, Neary D, Schellenberg GD, Beach TG, Mesulam M, Mann D, Grafman J, Mackenzie IR, Feldman H, Bird T, Petersen R, Knopman D, Boeve B, Geschwind DH, Miller B, Wszolek Z, Lippa C, Bigio EH, Dickson D, Graff-Radford N, Hutton M. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. Lancet Neurol. 2007 Sep 6; Epub.
Filley CM, Rollins YD, Alan Anderson C, Arciniegas DB, Howard KL, Murrell JR, Boyer PJ, Kleinschmidt-Demasters BK, Ghetti B. The Genetics of Very Early Onset Alzheimer Disease. Cogn Behav Neurol. 2007 Sep;20(3):149-156.

Abstracts

Ghetti, B.; Amati, A.; Turra, M.V.; Pacini, A.; Del Vecchio, M.; and Guazzi, G. C.: La malattia di Werdnig-Hoffmann-Wohlfart-Kugelberg-Welander. Unicità nosologica e diversità delle forme cliniche anche intrafamiliari. Rivista di Anatomia Patologica e di Oncologia, 36:19, 1970.
Guazzi, G.C.; Cecio, A.; Ghetti, B.; Del Vecchio, M.; and Striano, S.: Una mucopolisaccaridosi peculiare: epilessia-mioclonica dell'adulto con macchia rosso-ciliegia al fondo dell occhio. (Studio genetico, clinico, biologico ed ultrastrutturale). Rivista di Anatomia Patologica e di Oncologia, 36:20, 1970.
Ghetti, B.; Horoupian, D.; and Wisniewski, H.: Neuronal response to deafferrentation (simian lateral geniculate body as a model). Journal of Neuropathology and Experimental Neurology, 31:168, 1972.
Ghetti, B.; and Wisniewski, H.M.: Fate of synaptic membranes during degeneration of optic nerve terminals in the lateral geniculate nucleus. Journal of Cell Biology, 55:84a, 1972.
Cook, R.D.; Ghetti, B.; and Wisniewski, H.M.: The response of oligodendroglia to optic nerve transection in young and adult cats and monkeys. Journal of Cell Biology, 55:50a, 1972.
Ghetti, B.; Wisniewski, H.M.; Cook, R.D.; and Schaumburg, H.: Changes in the CNS after acute and chronic acrylamide intoxication. American Journal of Pathology, 70:78a, 1973.
Horoupian, D.S.; Ghetti, B.; and Wisniewski, H.M.: Retrograde transneuronal degeneration of optic nerve terminals EM study. Journal of Neuropathology and Experimental Neurology, 32:160, 1973.
Wisniewski, H.M.; Ghetti, B.; and Terry, R.D.: Neuritic (senile) plaques and neurofibrillar filamentous changes in aged rhesus monkeys. Journal of Neuropathology and Experimental Neurology, 32:160, 1973.
Schaumburg, H.H.; Spencer, P.S.; Wisniewski, H.M.; Ghetti, B.; and Cook, R.D.: Experimental acrylamide neuropathy a light microscopic, ultrastructural and clinical study. Journal of Neuropathology and Experimental Neurology, 32:170, 1973.
Ghetti, B.; Kristensson, K.; and Wisniewski, H.M.: Transfer of herpes simplex virus in the optic system. Journal of Neuropathology and Experimental Neurology, 33:174, 1974.
Cook, R.D.; Ghetti, B.; and Wisniewski, H.M.: Wallerian degeneration of kitten optic nerves. Journal of Neuropathology and Experimental Neurology, 33:185, 1974.
Wisniewski, H.M.; Ghetti, B.; Spencer, P.S.; and Terry, R.D.: Neuritic (senile) plaque an expression of a cortical form of axonal dystrophy. Journal of Neuropathology and Experimental Neurology, 33:187, 1974.
Horoupian, D.S.; Ghetti, B.; and Wisniewski, H.M.: Response of lateral geniculate nucleus of the rhesus monkey to ipsilateral occipital lobectomy. E.M. Study. Journal of Neuropathology and Experimental Neurology, 33:188, 1974.
Korthals, J.; Wisniewski, H.M.; Ghetti, B.; and Cook, R.D.: Pattern of Wallerian degeneration in nerve fibers of the Pacinian corpuscle. Journal of Neuropathology and Experimental Neurology, 33:189, 1974.
Schmidt, M.J.; and Ghetti, B.: Studies on the cyclic AMP system in human brain during aging. Society for Neuroscienoce Abstracts, 3:118, 1977.
Ghetti, B.; and Ochs, S.: Maytansine-induced block of axoplasmic transport and microtubule loss. Society for Neuroscience Abstracts, 3:30, 1977.
Lacey, D.J.; and Ghetti, B.: Dendritic hippocampal abnormalities in a case of partial Trisomy of the first chromosome: a Golgi study. Neurology, 28:385, 1978.
Ghetti, B.; and Ochs, S.: On the relation between microtubule density and axoplasmic transport in nerves treated with maytansine. Abstracts of International Symposium on Peripheral Neuropathies, Milan, June 26-28, 1978, in Ricerca Scientifica ed educazione permanente Suppl. 5:4, 1978, and in Muscle and Nerve, 1:503, 1978.
Ghetti, B.; Alyea, C.J.; and Muller, J.: Studies on the Purkinje cell degeneration (pcd) mutant: Primary pathology and transneuronal changes. Abstracts of the VIIIth International Congress of Neuropathology, Journal of Neuropathology and Experimental Neurology, 37:617, 1978.
Ghetti, B.: Effects of some maytansinoids on the central nervous system neurons. Society for Neuroscience Abstracts, 4:331, 1978.
Schmidt, M.J.; Ghetti, B.; Maggi, A.; and Enna, S.J.: Studies of receptor binding and cyclic AMP synthesis in the brains of young and old humans post-mortem. Society for Neuroscience Abstracts, 4:520, 1978.
Ghetti, B.: Maytansine induced neurofibrillary degeneration. Journal of Neuropathology and Experimental Neurology, 38:314, 1979.
Schmidt, M.J.; Truex, L.L.; Sawyer, B.D.; and Ghetti, B.: Neurochemical studies on the cerebellum of the Purkinje cell degeneration (pcd) mutant. Journal of Neuropathology and Experimental Neurology, 38:339, 1979.
Ghetti, B.; Alyea, C.J.; and Muller, J.: The Purkinje cell degeneration mutant (pcd): a model for selective neuronal loss and its sequelae. Abstracts of the meeting on Aging of the Brain and Dementia, satellite meeting of the VII International Meeting of the International Society for Neurochemistry, 1979.
Ghetti, B.: Experimental studies on neurofibrillary degeneration. Abstracts of the meeting on Aging of the Brain and Dementia, satellite meeting of the VII International Meeting of the International Society of Neurochemistry, 1979.
Ghetti, B; Alyea, C.J.; and Muller, J: Granule cell degeneration in the cerebellum of the Purkinje cell degeneration (pcd) mutant mouse. Society for Neuroscience Abstracts, 5:100, 1979.
Truex, L.L.; Ghetti, B.; and Schmidt, M.J.: Cyclic nucleotides and beta-adrenergic binding in the cerebellum of pcd (Purkinje cell degeneration) mutant mice during Purkinje and granule cell degeneration. Society for Neuroscience Abstracts 5:418, 1979.
Azzarelli, B.; Muller, J.; Ghetti, B.; Dyken, M.; and Conneally, P.M.: A familial parkinson-dementia-ataxia syndrome with Kuru-like plaques in the cerebellum. Journal of Neuropathology and Experimental Neurology, 39:330, 1980.
Ghetti, B.; Sawyer, B.; Hemrick, S.; Fuller, R; and Schmidt, M.: Catecholamine concentration in the cerebellum of Purkinje cell degeneration (pcd) mutant mice. Journal of Neuropathology and Experimental Neurology, 39:355, 1980.
Patel, V.; Pullarkat, R.; Goebel, H.; Siegismund, G.; Ghetti, B.; and Muller, J.: Docosahexaenoic acid in infantile (Santavuori-Haltia) and late infantile (Jansky-Bielschowsky) ceroid lipofuscinosis. Journal of Neuropathology and Experimental Neurology, 39:381, 180.
Sawyer, B.D.; Hemrick-Luecke, S.; Schmidt, M.J.; Fuller, R.W.; and Ghetti, B.: Catecholamine and cyclic nucleotide concentrations in the cerebellum of pcd mutant mice. Society for Neuroscience Abstracts, 6:442, 1980.
Ghetti, B.: The Maytansinoids, A New Class of Tubulin Binding Agents. Effects on the Neuronal Cytoskeleton and the Axoplasmic Transports. Session 6, Workshop on Axoplasmic Transport, Schloss Elmau, Federal Republic of Germany, April 27-May 2, 1981.
Ghetti, B.; Autilio-Gambetti, L; and Gambetti, P.: Immunocytochemical characterization of the neurofibrillary tangles in maytansine encephalopathy. Journal of Neuropathology and Experimental Neurology, 40:313, 1981.
Kim, S.U.; Sato, Y,; and Ghetti, B.: Experimental neurofibrillary egeneration in cultured neurons induced by maytansinoids. Annals of Neurology, 10:68, 1981.
Schmidt, M.J.; Sawyer, B.D.; Perry, K.W.; Fuller, R.W.; Foreman, M.M.; and Ghetti, B.: Evidence for dopamine deficiency in the weaver mouse. Society for Neuroscience Abstracts, 7:208, 1981.
Ghetti, B.; and Bugiani, O.: Aluminum (Al) powder induces a slowly progressing encephalomyelopathy in adult rabbits. Journal of Neuropathology and Experimental Neurology, 41:360, 1982.
Sato, Y.; Kim, S.U.; and Ghetti, B.: Neurofibrillary tangle formation in cultured neurons. Journal of Neuropathology and Experimental Neurology, 41:341, 1982.
Bugiani, O.; and Ghetti, B.: A slowly progressing encephalomyelopathy induced in adult rabbits by aluminum powder. Abstracts of the IXth International Congress of Neuropathology, Page 32, Vienna, September 5-10, 1982.
Ghetti, B.; Alyea, C.; Hillman, D.; and McBride, W.: Pcd (Purkinje cell degeneration) mutant mouse: Morphometric and neurochemical analysis of the cerebellum after the Purkinje cell (PC) loss. Abstracts of the IXth International Congress on Neuropathology, Page 69, Vienna, September 5-10, 1982.
Vaccarino, F. M.; Ghetti, B.; Rea, M. A.; and Aprison, M. H.: Benzodiazepine receptors are not exclusively located on Purkinje cells: A study with the PCD mutant mouse. Society for Neuroscience Abstracts, 8:11, 1982.
Ghetti, B.; and Bugiani, O.: Cerebellar atrophy in aluminum encephalopathy. Journal of Neuropathology and Experimental Neurology, 42:331, 1983.
Ghetti, B.; Goheen, M.; and Bugiani, O.: Progressive deterioration of the cerebellar circuitry in aluminum encephalomyelopathy. Society for Neuroscience Abstracts, 9:273, 1983.
Triarhou, L.C.; Norton, J.; Bugiani, O.; and Ghetti, B.: Encefalopatia sperimentale da alluminio. L'assonopatia delle radici anteriori in rapporto con la degenerazione neurofibrillare dei motoneuroni spinali. Proceedings of the XXI Meeting of the Neuropathology Section of the Italian Society of Neurology, Page 27; (Siena, Italy, June 29-July 2, 1985).
Bugiani, O.; Tagliavini, F.; Bouras, C.; Costantinidis, J.; and Ghetti, B.: Dominanza emisferica e placche senili nella malattia di Alzheimer. Proceedings of the XXI Meeting of the Neuropathology Section of the Italian Society of Neurology, Page 49 (Siena, Italy, June 29 - July 2, 1985).
Ghetti, B.; Goheen, M.; and Bugiani, O.: Ultrastructural study of the Purkinje cell degeneration in aluminum encephalopathy. Annals of Neurology, 18:143, 1985.
Triarhou, L.C.; Alyea, C. and Ghetti, B.: Ultrastructure of monoamine-containing fibers in the cerebellar cortex of pcd mutant mice. Annals of Neurology, 18:145, 1985.
Triarhou, L.C.; Norton, J.; Alyea, C. and Ghetti, B.: A quantitative study of the granule cells in the Purkinje cell degeneration (pcd) mutant. Annals of Neurology, 18:146, 1985.
Felten, D.L.; Felten, S.Y.; Nurnberger, J.I. and Ghetti, B.: Lasting reorganization of noradrenergic fibers in the cerebellar cortex of Purkinje cell degeneration (pcd) mice. Annals of Neurology, 18:145, 1985.
Triarhou, L.C.; Norton, J.; Bugiani, O. and Ghetti, B.: Ventral root axonopathy associated with the neurofibrillary degeneration of lower motor neurons in experimental aluminum encephalomyelopatny. Society for Neuroscience Abstracts, 11:155, 1985.
Ghetti, B.; Felten, S.Y.; Nurnberger, J.I.; Costanzo, M.; Perry, K.; Fuller, R.W.; Alyea, C.J. and Felten, D.L.: Persistence of noradrenergic fibers in the cerebellar cortex of Purkinje cell degeneration (pcd/pcd) mutant mice following degeneration of Purkinje cells and granule cells. Society for Neuroscience Abstracts, 11:830, 1985.
Vincent, I.; Hofstetter, J.R.; Ghetti, B.; Richter, J. and Shea, P.: Effects of aluminum in vivo on neurotransmitter-synthesizing enzymes in rabbits. Society for Neuroscience Abstracts, 11:634, 1985.
Perry, K.W.; Fuller, R.W.; and Ghetti, B.: Norepinephrine turnover in cerebellum and other brain regions of pcd mutant mice. Society for Neuroscience Abstracts, 11:1209, 1985.
Low, W.C.; Triarhou, L.C.; and Ghetti, B.: Cerebellar transplant into mutant mice with Purkinje cell degeneration. Abstracts of the Conference on Cell and Tissue Transplantation into the Adult Brain. The New York Academy of Sciences, New York, 1986.
Bugiani, O.; Constantinidis, J.; Ghetti, B.; Bouras, C.; and Tagliavini F.: Asymmetric cerebral atrophy in Alzheimer disease. The Italian Journal of Neurological Sciences, 7:282, 1986.
Tagliavini, F.; Bouras, C.; Ghetti, B.; Constantinidis, J.; and Bugiani, O.: Intracortical distribution of senile plaques in the angular gyrus of Alzheimer patients. The Italian Journal of Neurological Sciences, 7:282, 1986.
Ghetti, B.; Goheen, M.; and Bugiani, O.: Ultrastructural study of Purkinje cell degeneration in aluminum encephalopathy. The Italian Journal of Neurological Sciences, 7:290, 1986.
Triarhou, L.C.; and Ghetti, B.: Monoaminergic nerve terminals survive the loss of their target Purkinje cells in the cerebellar cortex of Purkinje cell degeneration (pcd) mutant mice. Journal of Neuropathology and Experimental Neurology, 45:373, 1986.
Ghetti, B.; and Triarhou, L.C.: Nerve cell atrophy and loss in the inferior olivary complex of Purkinje cell degeneration (pcd) mutant mice. Journal of Neuropathology and Experimental Neurology, 45:363, 1986.
Bugiani, O.; Constantinidis, J.; Ghetti, B.; Bouras, C.; and Tagliavini, F.: Asymmetric cerebral atrophy in Alzheimer's disease. Journal of Neuropathology and Experimental Neurology, 45:342, 1986.
Tagliavini, F.; Bouras, C.; Ghetti, B.; Constantinidis, J.; and Bugiani, O.: Alzheimer's Disease (AD): Absence of side-to-side and patient-to-patient differences in the intracortical distribution of senile plaques (SP) in the angular gyrus. Journal of Neuropathology and Experimental Neurology, 45:361, 1986.
Triarhou, L.C.; Ghetti, B.; and Low, W.C.: Purkinje and granule cell survive in cerebellar grafts implanted into hosts with genetically-determined Purkinje or granule cell degeneration. Annals of Neurology, 20:138, 1986.
Ghetti, B.; Low, W.C.; and Triarhou, L.C.: Cerebellar transplants in mice with inherited Purkinje and granule cell loss. Abstracts of the X International Congress of Neuropathology, Stockholm, Page 11, 1986.
Ghetti, B.; Norton, J.; and Triarhou, L.C.: Anterograde transneuronal atrophy and loss in the deep cerebellar nuclei of 'Purkinje cell degeneration' mutant mice. Abstracts of the X International Congress of Neuropathology, Stockholm, Page 385, 1986.
Triarhou, L.C; Norton, J.; and Ghetti, B.: Morphometric analysis of the inferior olivary complex in pcd mutant mice. Neuroscience Letters, Suppl., 26:111, 1986.
Triarhou, L.C.; Low, W.C.; and Ghetti B.: Intracerebral grafting of embryonic substantia nigra into a genetic model of nigrostriatal degeneration. Abstracts of the IVth Congress of the International Society of Greek Neuroscientists, Patras, P. 14, 1986.
Triarhou, L.C.; Ghetti, B.; and Low, W.C.: Analysis of genetic and epigenetic components in the phenotypic expression of neurological mutations by means of cerebellar transplantation. Abstracts of the IVth Congress of the International Society of Greek Neuroscientists, Patras, P. 21, 1986.
Ghetti, B.; Triarhou, L.C.; and Low, W.C.: Transplantation of cerebellar grafts into adult 'Purkinje cell degeneration' (pcd) and weaver mutant mice. Society for Neuroscience Abstracts, 12:1291, 1986.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Reinnervation of the dopamine depleted striatum of adult weaver mutant mice by grafted mesencephalic dopaminergic neurons. Society for Neuroscience Abstracts, 12:1477, 1986.
Norton, J.; Triarhou, L.C.; and Ghetti, B.: Nerve cell atrophy and loss in the deep cerebellar nuclei of 'Purkinje cell degeneration' (pcd) mutant mice. Society for Neuroscience Abstracts, 12:982, 1986.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Dopaminergic mesencephalic grafts into the striatum of weaver (wv/wv) mutant hosts may compensate for the genetically determined loss of substantia nigra neurons. Journal of Cell Biology, 103:234a, 1986.
Low, W.C.; Kaseda, Y.H.; Triarhou, L.C.; Norton, J.; and Ghetti, B.: Improvement of locomotor coordination with transplants containing dopamine nerve cells in mutant mice with nigrostriatal dopamine deficiency. Federation Proceedings, 46:144, 1987.
Ghetti, B.; Triarhou, L.C.; and Low, W.C.: Genetically determined deficit of the mesencephalic dopamine cell system: Compensatory reinnervation of the dorsal neostriatum by neural grafts. Abstracts of the International Symposium on New Trends in Aging Research, Sirmione, Pg. 65, 1987.
Giaccone, G.; Tagliavini, F.; Street, J.S.; Ghetti, B.; and Bugiani, O.: Progressive supranuclear palsy (PSP): olivary neurons after deafferentiation contain phosphorylated neurofilaments (P-NF), tangles do not. The Italian Journal of Neurological Sciences, 8:194, 1987.
Triarhou, L.C.; Low, W.C.; Kaseda, Y.H.; Norton, J.; and Ghetti, B.: Long-term survival of ventral mesencephalic grafts reinnervating the neostriatum of adult weaver mutant mice. Journal of Neuropathology and Experimental Neurology, 46:352, 1987.
Kaseda, Y.H.; Low, W.C.; Richter, J.A.; Ghetti, B.; and Simon, J.R.: Upregulation of D2 receptors in the striatum of weaver mutant mice. Journal of Neuropathology and Experimental Neurology, 46:358, 1987.
Koo, H.; Ghetti, B.; Perry, G.; and Gambetti, P.: Abnormal phosphorylation of neurofilaments following administration of antimitotic drugs. Journal of Neuropathology and Experimental Neurology, 46:379, 1987.
Giaccone, G.; Street, J.S.; Tagliavini, F.; Ghetti, B. and Bugiani,O: Progressive supranuclear palsy (PSP): Olivary neurons after deafferentation contain phosphorylated neurofilaments (P-NF), tangles do not. Journal of Neuro-pathology and Experimental Neurology, 46:387, 1987.
Giaccone, G.; Tagliavini, F.; Street, J.S.; Ghetti, B.; and Bugiani, O.: Progressive supranuclear palsy: Phosphorylated neurofilament immuno-reactivity of neurofibrillary tangle-bearing neurons and of hypertrophic olivary neurons. Basic and Applied Histochemistry, 31(Supp1):88, 1987.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Homologous grafting of ventral mesencephalic anlagen to the striatum in a murine model of juvenile Parkinson's disease. Abstracts of the SCHMITT Neurological Sciences Symposium on Transplantation into the Mammalian CNS. Rochester, 1987.
Low, W.C.; Kaseda, Y.H.; Triarhou, L.C.; Norton, J.; and Ghetti, B.: Rotational behavior of mice with inherited nigrostriatal dopamine deficit and uni-lateral grafts of ventral mesencephalic dopamine neurons. Abstracts of the SCHMITT Neurological Sciences Symposium on Transplantation into the Mammalian CNS. Rochester, 1987.
Ghetti, B.; Norton, J.; and Triarhou, L.C.: Neuroanatomical definition of the mesostriatal dopamine deficit in weaver mutant mice. Neuroscience, 22:S783, 1987.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Reinnervation of the dopamine deficient frontal cortex of weaver mutant mice by grafted mesencephalic dopaminergic neurones. Neuroscience, 22:S257, 1987.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Dopamine neuron grafting in a murine model of genetic parkinsonism: Immunohistochemical, ultrastructural and behavioural correlates. IBRO Satellite Symposium on Functional Aspects of Neuronal Grafting in the Mammalian CNS. Pecs, 1987.
Ghetti, B.; and Triarhou, L.C.: Synaptic connectivity of dopamine afferents in the dorsal striatum of weaver mutant mice. Society for Neuroscience Abstracts, 13:285, 1987.
Low, W.C.; Triarhou, L.C.; Kaseda, Y.; Norton, J.; and Ghetti, B.: Functional innervation of the neostriatum in weaver mutant mice by grafted mesencephalic dopamine neurons. Society for Neuroscience Abstracts, 13:286, 1987.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Synaptology of dopamine afferents in the dorsal striatum of weaver mutant mice following grafting of ventral mesencephalic transplants. Society for Neuroscience Abstracts, 13:286, 1987.
Triarhou, L.C.; Brundin, P.; Doucet, G.; Murata, Y.; Low, W.C.; Björklund, A. and Ghetti, B.: Reconstruction of the mesostriatal dopamine pathway in weaver mutant mice by intrastriatal implants of dissociated nigral cell suspensions. Neurology, 38 (Suppl. 1):123, 1988.
Ghetti, B.; Farlow, M.; Conneally, M.; Azzarelli, B.; Masters, C.; Giaccone,G.; Tagliavini, F.; and Bugiani, O.: Amyloid plaques and neurofibrillary tangles of Gerstmann-Sträussler-Scheinker Disease. Neurology, 38 (Suppl. 1):266, 1988.
Farlow, M.R.; Conneally, M.P.; Azzarelli, B.; and Ghetti, B.: Familial Gerstmann-Sträussler-Sheinker: Extending the Clinical Spectrum. Neurology. 38 (Suppl. 1):324, 1988.
Chang, A.C.; Alyea, C.J.; Triarhou, L.C.; Low, W.C. and Ghetti, B.: Expression of the developmentally regulated polypeptide PEP-19 by Purkinje cells transplanted to the cerebellum of pcd mutant mice. Anatomical Record, 220:20A-21A, 1988.
Triarhou, L.C.; Brundin, P.; Doucet, G.; Björklund, A.; and Ghetti, B.: Reafferentation of mutant striatum by dopamine fibers originating in grafts of nigral cell suspensions. Anatomical Record, 220:99A, 1988.
Bugiani, O.; Martini, C.; Zecca, E.; Musicco, M.; Ghetti, B.; Giaccone, G.; and Tagliavini, F.: A quantitative assessment of the cerebral atrophy in Alzheimer disease. Journal of Neuropathology and Experimental Neurology, 47:340, 1988.
Kaseda, Y.; Ghetti, B.; Low, W.C.; Richter, J.A.; and Simon, J.R.: Agerelated changes in dopamine D2 receptors in the striatum of weaver mutant mice. Journal of Neuropathology and Experimental Neurology, 47:360, 1988.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Neuropeptide-dopamine co-existence in ventral mesencephalic grafts transplanted to the striatum of weaver mutant mice. Journal of Neuropathology and Experimental Neurology, 47:383, 1988.
Chang, A.C.; Triarhou, L.C.; Alyea, C.J.; Low, W.C.; and Ghetti, B.: Reactive gliosis in the cerebellum of pcd mutant host does not prevent the survival and differentiation of transplanted Purkinje cells. Journal of Neuropathology and Experimental Neurology, 47:384, 1988.
Ghetti, B.; Alyea, C.J.; Triarhou, L.C.; Dlouhy, S.R.; and Karn, R.C.: Purkinje cell degeneration* weaver double mutant mouse. Journal of Neuropathology and Experimental Neurology, 47:384, 1988.
Bugiani, O.; Martini, C.; Zecca, E.; Musicco, M.; Ghetti, B.; Giaccone, G.; and Tagliavini, F.: Misura dell'atrofia cerebrale nella malattia di Alzheimer. The Italian Journal of Neurological Sciences, 9:185, 1988.
Ghetti, B.; Farlow, M.; Conneally, M.; Azzarelli, B.; Masters, C.; Giaccone,G.; Tagliavini, F.; and Bugiani, O.: Placche amiloidi e degenerazione neuro-fibrillare nella malattia di Gerstmann-Sträussler-Scheinker. The Italian Journal of Neurological Sciences, 9:186, 1988.
Triarhou, L.C.; and Ghetti, B.: Stabilisation of neurone number in the inferior olivary complex of aged pcd mutant mice. European Journal of Neuroscience, Suppl 1:25, 1988
Doucet, G.; Brundin, P.; Seth, S.; Murata, Y.; Strecker, R.E.; Triarhou, L.C.; Ghetti, B.; and Björklund, A.: Regional density of dopamine innervation in the neostriatum of weaver mutant mouse: Effect of ventral mesencephalic grafts. European Journal of Neuroscience, Suppl. 1:307, 1988.
Chang, A.C.; Triarhou, L.C.; Alyea, C.J.; Low, W.C.; and Ghetti, B.: Development of wild-type Purkinje cells grafted to pcd mutant cerebellum during or after the degeneration of host Purkinje cells. European Journal of Neuroscience, Suppl. 1:309, 1988.
Bugiani, O.; Giaccone, G.; Verga, L.; Musicco, M.; Ghetti, B.; and Tagliavini, F.: A quantitative assessment of the cerebral atrophy in Alzheimer disease. Clinical Neuropathology, 7:151, 1988.
Ghetti, B.; Triarhou, L.C.; Chang, A.C.; Alyea, C.J.; Low, W.C.; Norton, J.; Fuller, R.W.; Schmidt, M.J.; and McBride, W.J.: Analysis of neuronal losses in the cerebellar circuitry of "Purkinje cell degeneration" mutant mice: Insight into strategies of neural transplantion. Clinical Neuropathology, 7:164, 1988.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Compensation of genetic mesostriatal dopamine deficiency by embryonic nigral transplants in weaver mutant mice. Clinical Neuropathology, 7:215, 1988.
Ghetti, B.; Alyea, C.J.; Triarhou, L.C.; Low, W.C.; Dlouhy, S.R.; and Karn, R.C.: The cerebellum in Purkinje cell degeneration* weaver (pcd/pcd /*wv/wv) double mutant mice. Society for Neuroscience Abstracts, 14:473, 1988.
Triarhou, L.C.; Brundin, P.; Doucet, G.; Björklund, A.; and Ghetti, B.: Dissociated nigral cell suspensions grafted to weaver striatum: a possible role for heterotopic dopaminergic dendrites? Society for Neuroscience Abstracts, 14:886, 1988.
Chang, A.C.; Alyea, C.J.; Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Comparative analysis of PEP-19 and 28-kDa Ca-binding protein expression in Purkinje cells grafted to pcd mutant cerebellum. Society for Neuroscience Abstracts,14:1144, 1988.
Ghetti, B.; Masters, C.L.; Tagliavini, F.; Giaccone, G.; Conneally, P.M.; Dlouhy, S.R.; Azzarelli, B.; Muller, J.; Manuelidis, E.E.; Bugiani, O.; and Farlow, M.R.: Cooperative studies of a large kindred of Gerstmann-Sträussler-Scheinker Disease. Abstracts of the symposium Molecular Neurobiology, The Aging Process and Neurodegenerative Disease.
Braun, C.; Farlow, M.R.; Azzarelli, B.; Tricot, G.; Giaccone, G.; Tagliavini, F.; Bugiani, O.; and Ghetti, B.: Familial Alzheimer disease with myelodysplastic disorder. Alzheimer disease and Associated Disorders, 3 [Suppl.1]:5, 1989.
Ghetti, B.; Tagliavini, F.; Masters, C.L.; Giaccone, G.; Conneally, P.M.; Azzarelli, B.; Farlow, M.R.; and Bugiani, O.: Indiana kindred of Gerstmann-Sträussler-Scheinker disease (GSSD): Neuropathologic studies of the fourth autopsied case. Alzheimer disease and Associated Disorders, 3 [Suppl.1]:23, 1989.
Giaccone, G.; Tagliavini, F.; Ghetti, B.; Frangione B.; and Bugiani, O.: Alzheimer's disease: widespread distribution of preamyloid deposits in the grey matter. Alzheimer disease and Associated Disorders, 3 [Suppl.1]:24, 1989.
Giaccone, G.; Tagliavini, F.; Ghetti, B.; Frangione B.; and Bugiani, O.: Alzheimer's disease: widespread distribution of preamyloid deposits in the grey matter. The Italian Journal of Neurological Sciences, 10:240, 1989.
Ghetti, B.; Triarhou, L.C.; Alyea, C.J.; Low, W.C.; and Chang, A.C.: Cerebellar transplants in pcd mutant mice: expression of Purkinje cells specific proteins in the graft and chronology of implantation relative to transsynaptic changes of the host. Restorative Neurology and Neuroscience, 1 [Suppl.1]:33, 1989.
Triarhou, L.C.; Low, W.C. and Ghetti, B.: Dopamine neuron grafting in the weaver mouse neostriatum: Histochemical phaenotypy, specificity of the striatal innervation, and behavioural improvement following bilateral transplantation. Restorative Neurology and Neuroscience, 1 [Suppl. 1]:53, 1989.
Triarhou, L.C.; Low, W.C. and Ghetti, B.: Intraparenchymal grafting of cerebellar cell suspensions to the deep cerebellar nuclei of pcd mutant mice. Rationale and histochemical organization. Society for Neuroscience Abstracts, 15:10, 1989.
Stotz, E.H.; Simon, J.R.; Ghetti, B.; and Richter, J.A.: Effect of MPTP on striatal dopamine levels in the weaver mutant mouse. Society for Neuroscience Abstracts, 15:97, 1989.
Simon, J.R.; Richter, J.A.; Ghetti, B.; and Vasko M.R.: Striatal and mesencephalic substance P content in the weaver mutant mouse and the effect of MPTP. Society for Neuroscience Abstracts, 15:97, 1989.
Ghetti, B.; and Triarhou, L.C.: Ultrastructural pathology of midbrain dopamine neurons in the weaver mutant mouse and progression of neuron loss with aging. Society for Neuroscience Abstracts, 15:654, 1989.
Hofstetter, J.R.; Wei, J.J.; Ghetti, B.; Nurnberger, J.I.; and Hodes, M.E.: CNS-specific probes from subtractive cDNA libraries. Society for Neuro-science Abstracts, 15:1128, 1989.
Low, W.C.; Triarhou, L.C.; Kaseda, Y.; Norton, J.; and Ghetti, B.: Bilateral nigral grafts to the striatum of weaver mutant mice enhance locomotor coordination. Society for Neuroscience Abstracts, 15:1355, 1989.
Yee, R.D.; Farlow, M.R.; and Ghetti, B.: Imbalance and dementia in an auto mechanic: a family affair. Abstract of The Frank B. Walsh Society 22^nd Ann. Meeting, 1990.
Yee, R.D.; Farlow, M.R.; Suzuki, D.A.; Betelak, K.F.; and Ghetti, B.: Eye movement in Gerstmann-Sträussler-Scheinker (GSS) disease. Investigative ophthalmology and visual science. Abstracts of the Annual Meeting of the Association for Research in Vision and Ophthalmology, 31(4):120, 1990.
Bugiani, O.; Verga, L.; Tagliavini, F.; Pollo, B.; Ghetti, B.; Frangione, B.; and Giaccone, G.: Neuritic changes in preamyloid deposits. Reunion commune de la société belge de neuropathologie, Anvers, May 19, 1990.
Yee, R.D.; Ghetti, B.; Farlow, M.R.; Suzuki, D.A.; and Betelak, K.F.: Gerstmann-Sträussler-Scheinker (GSS) disease in an Indiana family. Abstracts of the VIII International Neuro-Ophthalmology Symposium, Winchester, England, June 25-29, 1990.
Farlow, M.R.; Edwards, M.K.; Kuharik, M.; Giaccone, G.; Tagliavini, F.; Bugiani, O.; and Ghetti, B.: Magnetic resonance imaging in the Indiana kindred of Gerstmann-Sträussler-Scheinker disease. Neurobiology of Aging, 11:265, 1990.
Giaccone, G.; Tagliavini, F.; Verga, L.; Frangione, B.; Farlow, M.R.; Bugiani, O.; Ghetti, B.: Neurofibrillary tangles in the Indiana kindred of Gerstmann- Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease. Neurobiology of Aging, 11:280, 1990.
Hsiao, K.; Cass, C.; Conneally, P.M.; Dlouhy, S.R.; Hodes, M.E.; Farlow, M.R.; Ghetti, B.; Prusiner, S.B.: Atypical Gerstmann-Sträussler-Scheinker syndrome with neurofibrillary tangles: no mutation in the prion protein open-reading-frame in a patient of the Indiana kindred. Neurobiology of Aging, 11:302, 1990.
Tagliavini, F.; Prelli, F.; Ghiso J.; Bugiani, O; Farlow, M.R.; Ghetti, B.; Frangione, B.: Indiana kindred of Gerstmann-Sträussler-Scheinker disease: isolation of low molecular weight protein from amyloid plaque cores. Neurobiology of Aging, 11:304, 1990.
Bugiani, O.; Verga, L.; Tagliavini, F.; Pollo, B.; Ghetti, B.; Frangione, B.; Giaccone, G.: Synaptic alterations in preamyloid deposits. Neurobiology of Aging, 11:310, 1990.
Ghetti, B.; and Triarhou, L.C.: Degeneration and loss of mesencephalic dopamine neurons in weaver mutant mice during life span. Abstracts of the Satellite Meeting of the XIth International Congress of International Union of Pharmacology. Dopamine '90; Dopaminergic systems and their regulations, Como, Italy, July 8-11, 1990.
Triarhou, L.C.; and Ghetti, B.: Dopaminergic dendrites in the substantia nigra pars reticulata of the weaver mouse: Identification of a defective phaenotype shared heterozygous and homozygous mutants. European Journal of Neuroscience, Suppl. 3:108, 1990.
Ghetti, B.; Triarhou, L.C.; Alyea, C.J.; Dlouhy, S.R.; and Karn, R.C.: Unique cerebellar phenotype combining granule and Purkinje cell loss: Morphological evidence for weaver * pcd double mutant mice. European Journal of Neuroscience, Suppl. 3:204, 1990.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Cerebellar serotonin fiber innervation in normal and pcd mutant mice and host afferents into intraparenchymal cerebellar grafts. Society for Neuroscience Abstracts, 16: 834,1990.
Yu, H.; Simon, J.R.; Richter, J.A.; Vasko M.R.; and Ghetti, B.: Resting and evoked release of endogenous dopamine in striatal slices from the weaver mutant mouse. Society for Neuroscience Abstracts, 16:932, 1990.
Simon, J.R.; Dunnington A.B.; Yu, H.; and Ghetti, B.: Uptake of dopamine, choline and GABA in the striatum of weaver mutant mice: topographical distribution. Society for Neuroscience Abstracts, 16:932, 1990.
Ghetti, B.; and Triarhou, L.C.: Profile of mesencephalic dopamine neuron loss in weaver mutant mice during life-span. Society for Neuroscience Abstracts, 16:1138, 1990.
Stotz, E.H.; Simon, J.R.; and Ghetti, B.: Dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse. Society for Neuroscience Abstracts, 16:1138, 1990.
Farlow, M.R.; Bugiani, O.; Giaccone, G.; Tagliavini, F.; and Ghetti, B.: Neuropathology of presymptomatic Gerstmann-Sträussler-Scheinker Disease of the Indiana kindred. Neurology, 41 (Suppl. 1):119, 1991.
Giaccone, G.; Tagliavini, F.; Bugiani, O.; Frangione, B.; Farlow, M. R.; and Ghetti, B.: PrP and ß-amyloid coexist in plaques of an aged patient of the Indiana kindred of Gerstmann-Sträussler-Scheinker Disease. Neurology, 41 (Suppl. 1):155, 1991.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Dopaminergic-cholinergic interactions following transplantation of ventral mesencephalic grafts to the weaver mutant mouse. Neurology, 41 (Suppl. 1):398, 1991.
Giaccone, G.; Tagliavini, F.; Verga, L.; Frangione, B.; Farlow, M.R.; Ghetti, B.; and Bugiani, O.: Indiana kindred with Gerstmann-Sträussler-Scheinker disease: Neurofibrillary tangles and neurites of plaques with PrP amyloid share antigenic determinants with those of Alzheimer disease. Clinical Neuropathology, 10:99-100, 1991.
Tagliavini, F.; Prelli, F.; Ghiso J.; Giaccone, G; Bugiani, O; Serban, D.; Prusiner, S.B.; Farlow, M.R.; Ghetti, B.; Frangione, B.: Biochemical characterization of amyloid protein of Gerstmann-Sträussler-Scheinker disease (GSS),in Indiana kindred. Clinical Neuropathology, 10:100, 1991.
Kuwabara, T.; Yee, R.D.; Farlow, M.R.; and Ghetti, B.: Histologic study of ocular tissues in Gerstmann-Sträussler-Scheinker (GSS) disease. Investigative ophthalmology and visual science. Abstracts of the Annual Meeting of the Association for Research in Vision and Ophthalmology, 32(4):761, 1991.
Ghetti, B.; Farlow, M.R.; Frangione, B.; Giaccone, G.; Tagliavini, F.; and Bugiani, O.: Natural history of Gerstmann-Sträussler-Scheinker disease (GSS) in the Indiana kindred (IK). Journal of Neuropathology and Experimental Neurology, 50:317, 1991.
Tagliavini, F.; Prelli, F.; Ghiso J.; Giaccone, G; Bugiani, O; Serban, D.; Prusiner, S.B.; Farlow, M.R.; Ghetti, B.; and Frangione, B.: Amyloid protein of Gerstmann-Sträussler-Scheinker disease (GSS), Indiana kindred. Journal of Neuropathology and Experimental Neurology, 50:341, 1991.
Triarhou, L.C.; and Ghetti, B.: Dopaminergic dendrites in substantia nigra pars reticulata and weaver gene action. Journal of Neuropathology and Experimental Neurology, 50:375, 1991.
Giaccone, G.; Tagliavini, F.; Verga, L.; Frangione, B.; Farlow, M.R.; Ghetti, B.; and Bugiani, O.: Coexistence of prion protein and ß-protein in an aged patient with Gerstmann-Sträussler-Scheinker disease. Clinical Neuropathology, 10:153, 1991.
Tagliavini, F.; Prelli, F.; Ghiso J.; Ghetti, B.; Farlow, M.R.; Giaccone, G; Bugiani, O.; and Frangione, B.: Amyloid protein of Gerstmann-Sträussler-Scheinker disease. Clinical Neuropathology, 10:166, 1991.
Dlouhy, S.R.; Farlow, M.R.; Ghetti, B.; Johnson P.; Foroud, T.; Conneally, P.M.; and Hodes, M.E.: Preliminary linkage analysis of Gerstmann-Sträussler-Scheinker (GSS) disease in the Indiana kindred. The American Journal of Human Genetics, 49 (Supplement):339, 1991.
Ghetti, B.; Tagliavini, F.; Farlow, M.R.; Yee, R.; Giaccone, G.; Frangione B.; Bugiani, O.; Conneally, P.M.; Hodes, M.E.; Dlouhy, S.R.; Hsiao, K. ; and Prusiner, S.B.: Coexistence of PrP amyloid and Alzheimer neurofibrillary tangles in the Indiana-kindred variant of Gerstmann-Sträussler-Scheinker disease with mutation at codon 198 of PRNP gene. Abstracts of the International Symposium "Prion diseases in human and animals". London, England, September 2-4, 1991.
Ghetti, B.; Triarhou L.C.; and Fuller, R.W.: Cerebellar monoamines in neurological mutant mice. Abstracts of the International Symposium "Monoaminergic cerebellar systems and ataxia". Lyon, France, September 11-12, 1991.
Bugiani, O.; Giaccone, G.; Verga, L.; Pollo, B.; Frangione, B.; Ghetti, B.; and Tagliavini, F.: Immunoreactivity of cerebral preamyloid deposits with anti-bodies to synaptophysin, ALZ-50, N- and C-terminal domain of the amyloid precursor protein. Revue Neurologique, 147:689, 1991.
Triarhou L.C.; and Ghetti, B.: Further characterization of the dopaminergic dendrite deficit in substantia nigra pars reticulata of heterozygous and homozygous weaver mutant mice: Golgi, MAP2 and synaptic connectivity studies. Society for Neuroscience Abstracts, 17:159, 1991.
Stotz, E.H.; Ghetti, B.; and Simon, J.R.: Increased serotonin levels in the striatum of the weaver mutant mouse. Society for Neuroscience Abstracts, 17:159, 1991.
Richter, J.A.; Yu, H.; Ghetti, B.; and Simon, J.R.: Enhanced stimulation of dopamine release by serotonin in weaver mice. Society for Neuroscience Abstracts, 17:505, 1991.
Simon, J.R.; Miller, A.D.; and Ghetti, B.: Dopamine uptake in the substantia nigra: effect of the weaver gene. Society for Neuroscience Abstracts, 17:505, 1991.
Yu, H.; Ghetti, B.; and Simon, J.R.: Changes in striatal glutamic acid decarboxilase activity in weaver mutant mice. Society for Neuroscience Abstracts, 17:505, 1991.
Kambouris, M.; Sangameswaran, L.; Dlouhy, S.R.; Triarhou L.C.; Ghetti, B.; and Hodes, M.E.: Granule cell antiserum identifies a brain-specific cDNA in an expression library derived from neonatal heterozygous weaver cerebella. Society for Neuroscience Abstracts, 17:556, 1991.
Solà, C.; Mengod, G.; Low, W.C.; Ghetti, B.; Palacios, J.M. and Triarhou L.C.: ßAPP and GAP-43 gene expression in normal and weaver mice and in intra striatal dopamine neuron grafts. Society for Neuroscience Abstracts, 17:770, 1991.
Tagliavini, F.; Prelli, F.; Giaccone, G.; Porro, M.; Ghiso J.; Farlow, M.R.; Ghetti, B.; Bugiani, O.; and Frangione, B.: Microtubule-associated protein Tau is a component of neurofibrillary tangles of Gerstmann-Sträussler-Scheinker disease-Indiana kindred. Society for Neuroscience Abstracts, 17:1069, 1991.
Bugiani, O.; Constantinidis, J.; Ghetti, B.; Bouras, C.; and Tagliavini, F.: Asymmetric cerebral atrophy in Alzheimer's disease. The Italian Journal of Neurological Sciences, Suppl. 12:32, 1991.
Ghetti, B.; Farlow, M.R.; Frangione, B.; Giaccone, G.; Tagliavini, F.; and Bugiani, O.: Gerstmann-Sträussler-Scheinker disease in the Indiana kindred. The Italian Journal of Neurological Sciences, Suppl. 12:34, 1991.
Ghetti, B.; and Triarhou L.C.: Degenerazione ereditaria di neuroni dopaminergici nel topo mutante weaver, restaurazione unilateral del circuito nigrostriatale e induzione di comportamento motorio parossistico di origine extrapiramidale. Course on "Dystonia of childhood onset". Venezia, Italy, March 11-13, 1992.
Farlow, M.R.; Murrell, J.; Zeldenrust, S.; Ghetti, B.; and Benson, M. B.: Clinical, neuropathological and molecular genetic characteristics of a family with early onset Alzheimer's disease. Neurology, 42 (Suppl. 3):350, 1992.
Bugiani, O.; Giaccone, G.; Verga, L.; Pollo, B.; Frangione, B.; Tagliavini, F.; and Ghetti, B.: Amyloid precursor protein and ß-protein in GSS-Indiana kindred and their relation to PrP amyloid deposits. Clinical Neuropathology, 11:89, 1992.
Giaccone, G.; Verga, L.; Bugiani, O.; Frangione, B.; Serban, D.; Prusiner, S.B.; Farlow, M.R.; Ghetti, B.; and Tagliavini, F.: Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Clinical Neuropathology, 11:91, 1992.
Simon, J.R.; and Ghetti, B.: Neurochemistry of the nigrostriatal dopaminergic system in the weaver mutant mouse. Abstracts of the Meeting Dopamine '92. From neurobiology to neuropathology, Forte Hotel Village, Italy, May 16-20, 1992.
Vogelweid, C.M.; Verina, T.; Alyea C.; and Ghetti, B.: Predominantly postmitotic degeneration of germ cells in the adult male weaver mutant mouse: a structural correlate of infertility. Journal of Neuropathology and Experimental Neurology, 51:333, 1992.
Sangameswaran, L.; Haddle, K.R.; Ghetti, B.; Dlouhy, S.R.; and Hodes, M.E.: Differentially expressed cDNAs from a postnatal day zero cerebellar wv/+ subtracted cDNA library. Journal of Neuropathology and Experimental Neurology, 51:333, 1992.
Triarhou, L.C.; Low, W.C.; and Ghetti, B.: Development of cerebellar cell suspensions intraparenchymally transplanted to the deep cerebellar nuclei of pcd mutant mice. Journal of Neuropathology and Experimental Neurology, 51:349, 1992.
Kambouris, M.; Sangameswaran, L.; Triarhou L.C.; Dlouhy, S.R.; Ghetti, B.; and Hodes, M.E.: Granule cell (GC) antiserum identifies GC cDNAs in an expression library derived from neonatal heterozygous weaver cerebella. Journal of Neuropathology and Experimental Neurology, 51:350, 1992.
Solà, C.; Mengod, G.; Low, W.C.; Ghetti, B.; Palacios, J.M.; and Triarhou L.C.: GAP-43, MAP2 and ßAPP gene expression in the nigrostriatal system of normal and weaver mutant mice and in intrastriatal mesencephalic grafts. Journal of Neuropathology and Experimental Neurology, 51:351, 1992.
Dlouhy, S.R.; Hsiao, K.; Ghetti, B.; Farlow, M.R.; Foroud, T.; Conneally, P.M.; Prusiner, S.B.; and Hodes, M.E.: Gerstmann-Sträussler-Scheinker disease in the Indiana kindred is genetically linked to the prion protein gene (PRNP). Journal of Neuropathology and Experimental Neurology, 51:352, 1992.
Ghetti, B.; Farlow, M.R.; Murrell, J.; and Benson, M.D.: Hereditary Alzheimer disease with a guanine to thymine missense change at position 1,924 of the amyloid precursor protein (APP) gene. Journal of Neuropathology and Experimental Neurology, 51:369, 1992.
Bugiani, O.; Giaccone, G.; Verga, L.; Farlow, M.R.; Frangione, B.; Tagliavini, F.; and Ghetti, B.: Amyloid precursor protein (APP) and ß-protein immunoreactivity in Gerstmann-Sträussler-Scheinker disease-Indiana kindred (GSS-IK). Journal of Neuropathology and Experimental Neurology, 51:370, 1992.
Bugiani, O.; Giaccone, G.; Verga, L.; Pollo B.; Frangione, B.; Tagliavini, F.; and Ghetti, B.: Abnormal neurites immunoreactive with antibodies to APP and extracellular ß-protein in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Clinical Neuropathology, 11:222-223, 1992.
Giaccone, G.; Verga, L.; Bugiani, O.; Frangione, B.; Serban, D.; Prusiner, S.B.; Farlow, M.R.; Ghetti, B.; and Tagliavini, F.: Abnormal neurites immunoreactive with antibodies to APP and extracellular ß-protein in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Clinical Neuropathology, 11:224-225, 1992.
Triarhou, L.C.; Solà, C.; Landwehrmeyer, B.; García-Ladona, F.J.; Mengod, G.; Low, W.C.; Ghetti, B.; and Palacios, J.M.: Structural protein and receptor gene expression in mesencephalic cell suspensions transplanted to the weaver mouse neostriatum. Abstracts 7^th International catecholamine symposium: 317, 1992.
Farlow, M.R.; Bugiani, O.; Giaccone, G.; Tagliavini, F.; Ghetti, B.; and Dlouhy S.: A "presymptomatic" case of Gerstmann-Sträussler-Scheinker disease from the Indiana kindred has cerebellar deposits of prion protein amyloid and a mutation in the prion protein gene. Neurobiology of Aging, 13:S39, 1992.
Giaccone, G.; Verga, L.; Bugiani, O.; Frangione, B.; Serban, D.; Prusiner, S.B.; Farlow, M.R.; Ghetti, B.; and Tagliavini, F.: Prion protein preamyloid and amyloid deposits in the brains of patients with Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Neurobiology of Aging, 13:S39, 1992.
Ghetti B.; Farlow M.R.; Murrell J.; and Benson M.D.: Hereditary Alzheimer disease with a guanine to thymine missense change at position 1924 of the amyloid precursor protein (APP) gene. Neurobiology of Aging, 13:S65, 1992.
Dlouhy S.R.; Farlow M.; Hsiao K.; Foroud T.; Johnson P.; Conneally P.M.; Prusiner S.B.; Hodes M.E.; and Ghetti B.: Linkage of the Indiana kindred variant of Gerstmann-Sträussler-Scheinker disease to a mutation in the prion protein gene (PRNP). Neurobiology of Aging, 13:S70, 1992.
Triarhou, L.C.; and Ghetti, B.: Axonal monitoring of ventral mesencephalic grafts with antibodies against neural cell adhesion molecule, synaptophysin, phosphorylated and non-phosphorylated neurofilament epitopes. Restorative Neurology and Neuroscience (IVth International Symposium on Neural Transplantation), 4:159, 1992.
Triarhou, L.C.; Solà, C.; Landwehrmeyer, B.; García-Ladona, F.J.; Mengod, G.; Low, W.C.; Ghetti, B.; and Palacios, J.M.: Structural protein and receptor gene expression in ventral mesencephalic grafts transplanted to the striatum of weaver mouse. Restorative Neurology and Neuroscience (IVth International Symposium on Neural Transplantation), 4:160, 1992.
Triarhou, L.C.; Ghetti, B.; and Hingtgen J.: Recovery of motoric activities in weaver mutant mice following bilateral intrastriatal grafting of mesencephalic cell suspensions. Restorative Neurology and Neuroscience (IVth International Symposium on Neural Transplantation), 4:179, 1992.
Bugiani, O.; Giaccone, G.; Verga, L.; Pollo, B.; Farlow, M.R.; Frangione, B.; Tagliavini, F.; and Ghetti, B.: Gerstmann-Sträussler-Scheinker disease, Indiana kindred (GSS-IK): PRP and ßPP participate in the morphogenesis of amyloid plaques. Clinical Neuropathology, 11:222-223, 1992.
Kambouris, M.; Triarhou L.C.; Sangameswaran, L.; Dlouhy, S.R.; Ghetti, B.; and Hodes, M.E.: Identification of 15 novel cerebellar cDNAs by screening a neonatal heterozygous weaver cerebellar expression library with an anti-granule cell antiserum; molecular characterization, prenatal ontogeny, and cerebellar distribution of one novel cDNA in neurologically mutant mice and in human cerebellum. The American Journal of Human Genetics, Suppl. 51:A121, 1992.
Sangameswaran, L.; Haddle, K.R.; Ghetti, B.; Dlouhy, S.R.; and Hodes, M. E.: Isolation of cDNAs from a postnatal day 1 wv/+ subtracted cDNA library by differential screening. Society for Neuroscience Abstracts, 18:50, 1992.
Kambouris, M.; Triarhou L.C.; Sangameswaran, L.; Dlouhy, S.R.; Ghetti, B.; and Hodes, M.E.: Molecular characterization of a novel cerebellar cDNA, prenatal ontogeny, and cellular distribution in the brains of normal, weaver, PCD, and reeler mutant mice. Society for Neuroscience Abstracts, 18:53, 1992.
Ghetti, B.; and Triarhou L.C.: Nigrostriatal aberrations induced by the weaver gene are present at birth. Society for Neuroscience Abstracts, 18:156, 1992.
Wagner, S.L.; Read, S.L.; Van Nostrand, W.E.; Cunningham, D.D.; Peskind, E.; Davis, K.L.; Perl, D.; Ryan, T.; Ghetti, B.; Benson, M.B.; Farlow, M.R.; and Vinters, H.V.: Reduced levels of secreted amyloid ß-protein precursor in CSF of pathologically confirmed Alzheimer's disease patients. Society for Neuroscience Abstracts, 18:766, 1992.
Triarhou, L.C.; Ghetti, B.; and Simon, J.R.: Synaptosomal uptake of [3H]dopamine in the striatum of weaver mutant mice following intrastriatal transplantation of mesencephalic cell suspensions. Society for Neuroscience Abstracts, 18:930, 1992.
Tagliavini, F.; Prelli, F.; Verga, L.; Giaccone, G.; Salmona, M.; Passerini, F.; Wisniewski, T.; Ghetti, B.; Bugiani, O.; and Frangione, B.: Amyloid fibrils formed in vitro from prion protein segments. Society for Neuroscience Abstracts, 18:1251, 1992.
Triarhou, L.C.; Landwehrmeyer, B.; Low, W.C.; Norton, J.; Ghetti, B.; Palacios, J.M.; and Simon, J.R.: Functional effects of intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice assessed by amphetamine-induced rotational asymmetry, synaptosomal [3H]dopamine uptake and [3H] mazindol binding autoradiography. Abstracts of IBRO workshop on "Mechanisms of neuronal plasticity", University of Patras, Patras, Greece, 1992.
Triarhou, L.C.; Norton, J.; Ghetti, B.; and Hingtgen J.N.: Magnitude of graft-induced behavioural recovery after intrastriatal transplantation of foetal dopamine neurons as a function of the genetic stock of the recipient. Abstracts of IBRO workshop on "Mechanisms of neuronal plasticity", University of Patras, Patras, Greece, 1992.
Kambouris, M.; Hodes, M.E.; Ghetti, B.; and Triarhou, L.C.: Cellular localization of a novel cerebellar cDNA in the brain of normal, weaver, Purkinje cell degeneration, and reeler mutant mice. Abstracts of IBRO workshop on "Mechanisms of neuronal plasticity", University of Patras, Patras, Greece, 1992.
Tagliavini, F.; Giaccone, G.; Verga, L.; Frangione, B.; Gibbs, C.J.Jr; Farlow, M.R.; Ghetti, B.; and Bugiani, O.: Cytoskeletal abnormalities in dementias with neurofibrillary tangles of Alzheimer type. Neuroscience Letters, Suppl. 43:S108, 1992.
Simon, J.R.; and Ghetti, B.: The weaver mutant mouse as a model of neuronal degeneration of the nigrostriatal dopaminergic system: Neurochemical analyses. Abstracts of the First International Symposium "Transmissible and non transmissible neurodegenerative disorders: current update", Ocho Rios, Jamaica, February 28-March 5, 1993.
Ghetti, B.; Farlow, M.R.; Yee, R.; Frangione B.; Giaccone, G.; Tagliavini, F.; Bugiani, O.; Hsiao, K.; Dlouhy, S.R.; Conneally, P. M.; Hodes, M.E.; and Prusiner, S.B.: Dominant prion protein amyloidosis with neurofibrillary tangles: Natural history and molecular pathology. Abstracts of the First International Symposium "Transmissible and non transmissible neuro-degenerative disorders: current update", Ocho Rios, Jamaica, February 28-March 5, 1993.
Farlow, M.R.; Ghetti, B. ; Dlouhy, S.R.; Giaccone, G.; Bugiani, O.; Tagliavini, F.; and Wagner, S.: Cerebrospinal fluid levels of amyloid ß-protein precursor are low in an Indiana kindred with Gerstmann-Sträussler-Scheinker disease. Neurology, 43 (Suppl. 2):A193, 1993.
Ghetti, B.; Koo E.H.; Farlow, M.R.; Dlouhy, S.R.; Giaccone, G.; Bugiani, O.; and Tagliavini, F.: Comparison of the neuropathology of two forms of Gerstmann-Sträussler-Scheinker disease with mutations at codons 217 and 198 of the prion protein gene (PRNP). Neurology, 43 (Suppl. 2):A253, 1993.
Kambouris, M.; Sangameswaran, L.; Triarhou L.C.; Kozak, C.A.; Dlouhy, S.R.; Ghetti, B.; and Hodes, M.E.: Molecular characterization of two novel cDNAs obtained by antibody screening of a mouse cerebellar cDNA expression library. Journal of Neuropathology and Experimental Neurology, 52:287, 1993.
Stotz, E.H.; Triarhou, L.C.; Ghetti, B.; Norton, J.; Simon, J.R.; Landwehrmeyer, B.; and Palacios, J.M.: Monoaminergic interactionsin the weaver mouse neostriatum: synaptosomal uptake of [3H]dopamine uptake and [3H]serotonin and visualization of uptake sites with [3H]mazindol and [3H]citalopram binding autoradiography. Journal of Neuropathology and Experimental Neurology, 52:294, 1993.
Vakili, S.T.; Muller, J.; Ilangovan, S.; Reyes, M.G.; Ghetti, B.; Juvenile Alzheimer disease with ataxia. Journal of Neuropathology and Experimental Neurology, 52:301, 1993.
Bugiani, O.; Giaccone, G.; Verga, L.; Frangione, B.; Ghetti, B.; and Tagliavini, F.: Neuritic changes in cerebral amyloidoses. Clinical Neuropathology, 12 (Suppl. 1):S39, 1993.
Kambouris, M.; Sangameswaran, L.; Triarhou L.C.; Kozak, C.A.; Dlouhy, S.R.; Ghetti, B.; and Hodes, M.E.: Mouse cerebellar cDNA expression library screening: novel clones. Clinical Neuropathology, (Suppl. 1):S49, 1993.
Young, K.; Jones, C.K.; Lazzarini, A.; Golbe, L.I.; Zimmerman, T.R.; Dickson, D.W.; Vinters, H. V.; Hodes, M.E.; Dlouhy, S.R.; and Ghetti, B.: PRNP codon 129 polymorphism and Gerstmann-Sträussler-Scheinker (GSS) with mutation at codon 102. The American Journal of Human Genetics, 53(Suppl.), A 1258, 1993.
Dlouhy S.; Wang, Y.; Sangameswaran, L.; Ghetti, B.; and Hodes, M.E.: Isolation of chromosome 16 cDNA clones from a mouse newborn wv/+ cerebellar library. The American Journal of Human Genetics, 53(Suppl.), A 1598, 1993.
Beck, K.D.; Alexi, T.; Dugich-Diordievic, M.M.; Ghetti, B.; Irwin, I.; Knusel, B.; Langston, J.W.; Ohsawa, F.; Triarhou L.C.; Venero, J.L.; and Hefti, F.: Actions of NT-4/5 and BDNF in animal models of cholinergic and dopaminergic degeneration. Society for Neuroscience Abstracts, 19:658, 1993.
Witt, T.C.; Ghetti, B.; and Triarhou L.C.: Transplantation of heterozygous weaver and wild-type mesencephalic cell suspensions into the denervated striatum. Society for Neuroscience Abstracts, 19:863, 1993.
Stotz, E.H.; Ghetti, B.; and Simon, J.R.: Endogenous serotonin release from the dopamine deficient striatum of the weaver mutant mouse. Society for Neuroscience Abstracts, 19:1628, 1993.
Hodes, M.E.; Sangameswaran, L.; Wang, Y.; Dlouhy, S.R.; Ghetti, B.: Identification of chromosome 16 cDNA clones from a mouse newborn wv/+ library. Society for Neuroscience Abstracts, 19:1699, 1993.
Farlow, M.R.; Giaccone, G.; Tagliavini, F.; Bugiani, O.; Dlouhy, S.R.; Ghetti, B.: Clinical and neuropathologic phenotype of Gerstmann-Sträussler-Scheinker disease with mutation at codon 217 of the PRNP gene. Clinical Neuropathology, 13:150, 1994.
Ghetti, B.; Farlow, M.R.: Familial dementia and multiple system degeneration with neurofibrillary tangles in hypothalamus, brainstem and spinal cord. Clinical Neuropathology, 13:152, 1994.
Giaccone, G.; Frigerio, L.; Farlow, M.R.; Ghetti, B.; Tagliavini, F.; Bugiani, O.: Apolipoprotein E and apolipoprotein J immunoreactivity in Gerstmann-Sträussler-Scheinker disease. Clinical Neuropathology, 13:152, 1994.
Tagliavini, F.; Prelli, F.; Porro, M.; Rossi, G.; Giaccone, G.; Farlow, M.R.; Dlouhy, S.R.; Ghetti, B.; and Bugiani, O.: Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) contain only the prion protein encoded by the mutant allele. Clinical Neuropathology, 13:168, 1994.
Young, K.; Jones, C.K.; Lazzarini, A.; Golbe, L.I.; Zimmerman, T.R.; Dickson, D.W.; Vinters, H. V.; Hodes, M.E.; Dlouhy, S.; and Ghetti, B.: PRNP codon 129 polymorphism and Gerstmann-Sträussler-Scheinker (GSS) with mutation at codon 102. Clinical Neuropathology, 13:170, 1994.
Lee, W-H.; Lo, T.; Wang, G-M.; Si, K.; Triarhou, L.C.; and Ghetti, B.: Altered IGFBP-5 gene expression in the cerebellar external germinal layer of weaver mutant mice. Abstracts of the Meeting of the Endocrine Society, 76:139, 1994.
Tagliavini, F.; Prelli, F.; Porro, M.; Rossi, G.; Giaccone, G.; Farlow, M. R.; Dlouhy, S.R.; Ghetti, B.; Bugiani, O.: 7 KD Amyloid subunit in GSS disease (Indiana and Swedish kindreds) contains only PrP peptides derived from the mutant allele. Neurobiology of Aging, 15:S143, 1994.
Ghetti, B.; Dlouhy, S.R.; Giaccone, G.; Prelli, F.; Piccardo, P.; Farlow, M.R.; Frangione, B.; Bugiani, O.; and Tagliavini, F.: Gerstmann-Sträussler-Scheinker Disease (GSS). Neurobiology of Aging, 15:S151, 1994.
Bugiani, O.; Giaccone, G.; Frigerio, L.; Farlow, M.R.; Ghetti, B.; Tagliavini, F.: Apolipoprotein E and J immunoreactivity in Gerstmann-Sträussler-Scheinker disease. Neurobiology of Aging, 15:S156-S157, 1994.
Ghetti, B.; Farlow, M.R.; Dlouhy, S.R.: Presence of Calbindin D-28K in prion protein amyloid deposits. Abstracts of the Second International Symposium "Neurodegenerative disorders: Common molecular mechanisms", Ocho Rios, Jamaica, April 10-15, 1994.
Triarhou, L.C.; Norton, J.; Ghetti, B.: Hemispheric asymmetry of dopamine neuron number in rodent substantia nigra. Brain Pathology, 4:377, 1994.
Stotz, E.H.; Triarhou, L.C.; Ghetti, B.; Palacios, J.M.: Autoradiographic studies of serotonin receptors and uptake sites in mice with inherited nigrostriatal dopamine deficiency. Brain Pathology, 4:382, 1994.
Mengod, G.; Palacios, J.M.; Verina, T.; Ghetti, B.; and Triarhou, L.C.: Somatostatin, neuropeptide Y and cholecystokinin gene expression in mouse brain during chronic nigrostriatal dopamine deficiency. Brain Pathology, 4:384, 1994.
Verina, T.; Fitzpatrick, L.; Vogelweid, C.; and Ghetti, B.: Abnormal spermatogenesis in homozygous and heterozygous weaver mice. Brain Pathology, 4:394, 1994.
Tang, X.; Tao, Y.; Critser, E.; Hodes, E.; Dlouhy, S.; and Ghetti, B.: Studies of sterility in the neurological mutant mouse Purkinje cell degeneration (pcd). Brain Pathology, 4:394, 1994.
Lee, W.H.; Lo, T.; Ghetti, B.; Triarhou, L.C.: Altered IGFBP-5 gene expression in the cerebellar external germinal layer (EGL) of weaver (wv/wv) mutant mice. Brain Pathology, 4:395, 1994.
Solà, C.; Mengod, G.; Palacios, J.M.; Ghetti, B.; and Triarhou, L.C.: GAP-43 and MAP2 expression in normal and weaver cerebellum: Immunohistochemical and in situ hybridization studies. Brain Pathology, 4:395, 1994.
Verina, T.; Norton, J.; Richter, J.A.; Triarhou, L.C.; Ghetti, B.: The mesencephalic dopamine cell system normal in weaver heterozygous mice: neuron counts and TyrOHase activity. Brain Pathology, 4:395, 1994.
Wei, J.; Dlouhy, S.; Ghetti, B.; Hodes, M.E.: Microdissection and cloning of the C3-C4 region of mouse chromosome 16. Brain Pathology, 4:514, 1994.
Ghetti, B.; and Farlow, M.R.: Hereditary presenile dementia and multiple system degeneration with neurofibrillary tangles (NFT). Brain Pathology, 4:517, 1994.
Giaccone, G.; Frigerio, L.; Farlow, M.R.; Ghetti, B.; Tagliavini, F.; Bugiani, O.: Apolipoprotein E and apolipoprotein J immunoreactivity in Gerstmann-Sträussler-Scheinker disease. Brain Pathology, 4:520, 1994.
Chen, S.G.; Monari, L.; Brown, P.; Parchi, P.; Petersen, R.B.; Mikol, J.; Gray, F.; Cortelli, P.; Montagna, P.; Ghetti, B.; Goldfarb, L.G.; Gajdusek, D.C.; Lugaresi, E.; Gambetti, P.; and Gambetti, L.A.: Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Different prion proteins determined by a DNA polymorphism. Brain Pathology, 4:521, 1994.
Ghetti, B.; Giaccone, G.; Tagliavini, F.; Bugiani, O.; Dlouhy, S.R.; Farlow, M.R.: Gerstmann-Sträussler-Scheinker disease with mutation at codon 217 of the PRNP gene: Clinical and neuropathologic phenotype. Brain Pathology, 4:522, 1994.
Ghetti, B.; Piccardo, P.; Farlow, M.R.; Dlouhy, S.R.: Presence of Calbindin D-28k immunoreactivity in cerebellar prion protein (PrP) amyloid deposits of Gerstmann-Sträussler-Scheinker (GSS) disease. Brain Pathology, 4:522, 1994.
Piccardo, P.; Young, Y.; Jones, C.K.; Lazzarini, A.; Golbe, L.I.; Zimmerman, T.R.; Dickson, D. W.; Vinters, H.V.; Hodes, M.E.; Dlouhy, S.; Giaccone, G.; Tagliavini, F.; Bugiani, O.; Ghetti, B.: N- and C-terminal sequences of prion protein (PrP) are integrated in PrP deposits of Gerstmann-Sträussler-Scheinker (GSS) disease with mutation at PRNP codon 102. Brain Pathology, 4:525, 1994.
Triarhou, L.C.; Ghetti, B.; Hingtgen, J.N.; Palacios, J.M.; Simon, J.R.: Intrastriatal fetal mesencephalic grafts in weaver mutant mice: Biochemical and behavioural indices of functional recovery. Brain Pathology, 4:574, 1994.
Witt, T.C.; Solà, C.; Mengod, G.; Palacios, J.M.; Ghetti, B.; Triarhou, L.C.: Dopamine-containing mesencephalic grafts into the denervated striatum: assessment of the role of dopaminergic dendrites. Brain Pathology, 4:575, 1994.
Wang, Y.; Hodes, M.E.; Sangameswaran, L.; Triarhou, L.C.; Wei, J.; Ghetti, B.; and Dlouhy, S.: Isolation of clones from a subtracted mouse cerebellar cDNA library. Brain Pathology, 4:585, 1994.
Unverzagt, F.W.; Farlow, M.R.; Dlouhy S.R.; Norton, J.; Mercado, N.; Torke, A.M.; and Ghetti B.: Presymptomatic neuropsychological deficits in Gerstmann-Sträussler-Scheinker disease. Annals of Neurology, 36:272-273, 1994.
Catt, K.E.; Piccardo, P.; Farlow, M.R.; Markand, O.; Jones, C.; Young, K.; Dlouhy, S.; and Ghetti, B.: Familial Creutzfeldt-Jakob (CJD) with mutation at codon 200 of the RNP gene: Clinical and pathological studies on a case. Annals of Neurology, 36:314, 1994.
Wei, J.J.; Dlouhy, S.R.; Ghetti, B.; Zhu J.G.; Hodes, M.E.: Microdissection and cloning of mouse chromosome 16C3-C4 yields multiple polymorpohic markers. The American Journal of Human Genetics, 55:(Suppl), A206, 1994.
Bare, D.J.; Ghetti, B.; Richter, J.A.: Effect of the tyrosine kinase inhibitor genistein on endogenous dopamine release from striatal slices of normal and weaver mice. Society for Neuroscience Abstracts, 20:285, 1994.
Bayer, S.A.; Triarhou, L.C.; Thomas, J.D.; and Ghetti, B.: The weaver gene targets dopaminergic neurons generated during a specific temporal window in substantia nigra neurogenesis. Society for Neuroscience Abstracts, 20:688, 1994.
Wei, J.J.; Dlouhy, S.R.; Ghetti, B.; Zhu, J.G.; and Hodes, M.E.: A group of polymorophic markers obtained by microdissection of mouse chromosome 16C3-C4. Society for Neuroscience Abstracts, 20:832, 1994.
Duong, T.; Action, P.J.; and Ghetti, B.: In Vivo effects of the amyloid ß protein in the rat brain. Society for Neuroscience Abstracts, 20:1245, 1994.
Unverzagt, F.; Farlow, M.R.; Torke, A.M.; and Ghetti, B.: Neuro-psychological functioning in Gerstmann-Sträussler-Scheinker disease and Alzheimer's disease: A preliminary report. Journal of the International Neuropsychological Society 4:385, 1995.
Unverzagt, F.; Farlow, M.R.; Dlouhy S.; Torke, A.M.; and Ghetti, B.: Neuropsychological functioning in affected and at-risk Gerstmann-Sträussler-Scheinker disease patients. Journal of the International Neuropsychological Society 4:385, 1995.
Farlow, M.R.; Benson, M.D.; Unverzagt, F.W.; Hutchins, G.; Ghetti, B.; and Wagner, S.: Low cerebrospinal fluid concentration of soluble amyloid Beta-protein precursor predict disease in a gene carrier with hereditary Alzheimer's disease. Neurology, 45 (Suppl. 2):A472, 1995.
Ghetti, B.; Piccardo, P.; Ichimiya, Y.; Goedert, M.; Kitamoto, T.; Tateishi, J.; Spillantini, M.G.; Frangione, B.; Bugiani, O.; Giaccone, G.; Prelli, F.; Dlouhy, S.R.; and Tagliavini, F.: Prion protein amyloid angiopathy and Alzheimer neurofibrillary tangles in PRNP stop codon 145. Journal of Neuropathology and Experimental Neurology, 54:415, 1995.
Parchi, P.; Castellani, R.; Capellari, S.; Petersen, R.B.; Chen, S.G.; Young, K.; Farlow, M.; Trojanowski, J.Q.; Sima, A.; Ghetti, B.; and Gambetti, P.: Protease-resistant prion protein in sporadic Creutzfeldt-Jakob disease (CJD): Correlation with clinicopathological features and PrP genotype. Journal of Neuropathology and Experimental Neurology, 54:416, 1995.
Tagliavini, F.; Prelli, F.; Porro, M.; Rossi, G.; Giaccone, G.; Bird, T. D.; Young, K.; Piccardo, P.; Dlouhy, S.R.; Ghetti, B.; Bugiani, O.; Frangione, B.: Only mutant PrP participates in amyloid formation in Gerstmann-Sträussler-Scheinker disease with A>V substitution at PrP codon 117. Journal of Neuropathology and Experimental Neurology, 54:416, 1995.
Basheeruddin, K.; Ilangovan, S.; Lee, J.; Alfieri, E.; Faraldi, F.; Vakili, S.T.; Ghetti, B.; Reyes, M.G.: Immunohistochemical localization of apolipoprotein E and beta amyloid in Alzheimer's disease. Journal of Neuropathology and Experimental Neurology, 54:432, 1995.
Piccardo, P.; Young, K.; Jones, C.J.; Seiler, C.; Lazzarini, A.; Golbe, L.I.; Zimmerman, T.R.; Dickson, D.W.; Vinters, H.V.; Lennox, A.; Perlman, S. L.; McLachlan, D.C.; St George-Hyslop, P.; Giaccone, G.; Bugiani, O.; Tagliavini, F.; Dlouhy, S.R.; and Ghetti, B.: Gerstmann-Sträussler-Scheinker (GSS) disease (P102L): Prion protein (PrP) core deposits are best recognized by antibodies directed to epitopes spanning PrP residues 90-165. Journal of Neuropathology and Experimental Neurology, 54:448, 1995.
Young, K.; Piccardo, P.; Dlouhy, S.R.; Clark, H.B.; and Ghetti, B.: Gerstmann-Sträussler-Scheinker (GSS) disease with spinal atrophy. Journal of Neuropathology and Experimental Neurology, 54:448, 1995.
Bayer, S.A.; Ghetti, B.; Wills, K.V.; Triarhou, L.C.: Late generated midbrain dopaminergic neurons are targets of lethal weaver gene action. Journal of Neuropathology and Experimental Neurology, 54:472, 1995.
Wei, J.; Ghetti, B.; Feng, F.; Wang, Y.; Dlouhy, S.R.; Hodes, M.E.: Genetic mapping of genomic markers derived by micro-dissection of the distal portion of mouse chromosome 16. Journal of Neuropathology and Experimental Neurology, 54:472, 1995.
Piccardo, P.; Young, K.; Tagliavini, F.; Bugiani, O.; Dlouhy, S.R.; Ghetti, B.: Aspectos Geneticos, Mecanismos De Transmision E Implicancia En Medicina Humana De Las Enfermedades Causadas Por Priones. VII Congreso Argentino De Microbiologia, Buenos Aires, Argentina, May 8-11, 1995.
Ghetti, B.; Piccardo, P.; Ichimiya, Y.; Goedert, M.; Kitamoto, T.; Tateishi, J.; Spillantini, M.G.; Frangione, B.; Bugiani, O.; Giaccone, G.; Prelli, F.; Dlouhy, S.R.; and Tagliavini, F.: Prion protein (PrP) amyloid angiopathy and Alzheimer neurofibrillary tangles in PRNP stop codon 145. Neuropathology and Applied Neurobiology, 21(S1):44, 1995.
Tagliavini, F.; Prelli, F.; Porro, M.; Rossi, G.; Giaccone, G.; Bird, T.D.; Dlouhy, S.R.; Young, K.; Piccardo, P.; Ghetti, B.; Bugiani, O.; and Frangione, B.: Only mutant PrP participates in amyloid formation in Gerstmann-Sträussler-Scheinker disease with Ala>Val substitution at codon 117. Neuropathology and Applied Neurobiology, 21(S1):60, 1995.
Ghetti, B.; Dlouhy, S.R.; Farlow, M.R.; Giaccone, G.; Bugiani, O.; Tagliavini, F.: Prion protein genotypes and cellular pathology in Gerstmann-Sträussler-Scheinker disease. VI Congresso Della Societá Italiana Di Neuroscienze, Ricerca Scientifica Ed Educazione Permanente Suppl 99:133, 1995.
Ghetti, B.; Piccardo, P.; Ichimiya, Y.; Goedert, M.; Bugiani, O.; Giaccone, G.; Dlouhy, S.R.; Tagliavini, F.; and Spillantini, M.G.: Dementia with Y145Stop mutation of PRNP: abnormally phosphorylated τ (tau) protein and Alzheimer neurofibrillary tangles (NFT) coexist with prion protein cerebral amyloid angiopathy (PrP-CAA). Fourth Joint American Society for Cell Biology/European Molecular Biology Organization Conference, Cambridge, England, August 5-10, 1995; Abstracts, pag. 23.
Ghetti, B.; Goedert, M.; Spillantini, M.G.; and Farlow, M.R.: Hereditary multiple system degeneration with presenile dementia: abnormally phosphorylated t (tau) in nerve cells and glia. Fourth Joint American Society for Cell Biology/European Molecular Biology Organization Conference, Cambridge, England, August 5-10, 1995; Abstracts, pag. 32.
Simon, J.R.; Brenneman, M.; and Ghetti, B.: The dopamine transporter in the weaver mutant mouse: Differential sensitivity to dopamine uptake blockers. Society for Neuroscience Abstracts, 21:376, 1995.
Parchi, P.; Castellani, R.; Capellari, S.; Chen, S.G.; Petersen, R.B.; Young, K.; Farlow, M.; Trojanowski, J.Q.; Sima, A.; Ghetti, B.; and Gambetti, P.: Molecular pathology of sporadic Creutzfeldt-Jakob disease (CJD): Correlation with clinicopathological features and prion protein genotype. Society for Neuroscience Abstracts, 21:494, 1995.
Richter, J.A.; Ghetti, B.; Bare, D.J.: Protein tyrosine phosphorylation in three models of nigrostriatal dopamine depletion: Weaver mouse, MPTP and 6-OHDA. Society for Neuroscience Abstracts, 21:1135, 1995.
Hutchins, G.D.; Farlow, M.R.; Dlouhy, S.R.; Piccardo, P.; Ghetti, B.: Relationship between functional and structural abnormalities in Gerstmann-Sträussler-Scheinker disease, Indiana kindred (GSS-IK). Society for Neuroscience Abstracts, 21:1671, 1995.
Wei, J.J.; Hodes, M.E.; Wang, Y.; Feng, Y.; Ghetti, B.; Dlouhy, S.R.: Direct cDNA selection by hybridization of mouse cerebellar libraries against microdissected DNA pools from the MMU16 C3-C4 region. Society for Neuroscience Abstracts, 21:2111, 1995.
Dlouhy, S.R.; Wei, J.; Feng, Y.; Wang, Y.; Piva, R.; Ghetti, B.; Hodes, M.E.: Studies of Girk2 and Tiam1 in normal and weaver mice. Proceedings, Indiana University School of Medicine, Scientific Session, Page 26, 1996.
Ghetti, B.; Goedert, M.; Spillantini, M.G.; and Farlow, M.R.: Hereditary multiple system degeneration with presenile dementia: abnormally phosphorylated t (tau) in nerve cells and glia. Proceedings, Indiana University School of Medicine, Scientific Session, Page 27, 1996.
planetaryGhetti, B.; Piccardo, P.; Farlow, M.; Ichimiya, Y.; Goedert, M.; Frangione, B.; Bugiani, O.; Giaccone, G.; Dlouhy, S. R.; Tagliavini, F.; and Spillantini, M.G.: The PRNP genotype determines extracellular (prion protein) and intracellular (tau) pathologies. Proceedings, Indiana University School of Medicine, Scientific Session, Page 28, 1996.
Wei, J.; Dlouhy, S.; Wang, Y.; Fang, Y.; Ghetti, B.; Hodes, M.E.: High-density genetic mapping of genomic clones and expressed sequences obtained by microdissection of mouse chromosome 16. Proceedings, Indiana University School of Medicine, Scientific Session, Page 37, 1996.
Richter, J.A.; Ghetti, B.; and Bare, D.J.: Protein tyrosine phosphorylation in three models of nigrostriatal dopamine depletion: weaver mouse, MPTP and 6-OHDA. Proceedings, Indiana University School of Medicine, Scientific Session, Page 39, 1996.
Simon, J.R.; Brenneman, M.; and Ghetti, B.: The dopamine transporter in the weaver mutant mouse: Differential sensitivity to dopamine uptake blockers. Proceedings, Indiana University School of Medicine, Scientific Session, Page 40, 1996.
Tagliavini, F.; Prelli, F.; Salmona, M.; Giaccone, G.; Ghetti, B.; Bugiani, O.; Frangione, F.; and Forloni, G.: IIIrd International Symposium on Transmissible Subacute Spongiform Encephalopathies: Prion diseases and protection against transmission risks. Paris, France, March 18-20, 1996.
Cervenakova, L.; Goldfarb, L.G.; Brown, P.; Piccardo, P.; Cummings, J.L.; Nagle, J.; Vinters, H.V.; Kaur, P.; Kurillova, L.; Ghetti, B.; Gajdusek, D.C.: 24-Nucleotide deletion in the PRNP gene: Analysis of associated phenotypes. IIIrd International Symposium on Transmissible Subacute Spongiform Encephalopathies: Prion diseases and protection against transmission risks. Paris, France, March 18-20, 1996.
Ghetti, B.; Piccardo, P.; Farlow, M.R.; Dlouhy, S.R.; Tagliavini, T.; Giaccone, G.; and Bugiani, O.: Distribution of abnormally phosphorylated  in Gerstmann-Sträussler-Scheinker (GSS) disease with mutation at codon 198 of the prion protein gene (PRNP). Neurology, 46 (Suppl.):A187-A188, 1996.
Spillantini, M.G.; Goedert, M.; Crowther, R.A.; and Ghetti, B.: Familial multiple system degeneration with presenile dementia: A new hereditary disease with tau-positive neurofibrillary pathology. Abstracts of the LXI Cold Spring Harbor Symposium on Quantitative Biology. Function & Dysfunction in the Nervous System, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, May 29-June 5, 1996, page 147
Giaccone, G.; Frigerio, L.; Pollo, B.; Canciani, B.; Ghetti, B.; Tagliavini, F.; and Bugiani, O.: Topography of phosphorylated tau immunoreactivity in Alzheimer Disease, progressive supranuclear palsy and Pick's disease. Clinical Neuropathology, 15:172, 1996.
Migheli, A.; Attanasio, A.; Piva, R.; Wei, J.J.; Hodes, M.E.; Dlouhy, S.; Ghetti, B.: Apoptotic and non-apoptotic cell death in weaver mice. Clinical Neuropathology, 15:177, 1996.
Piva, R.; Wei, J.J.; Feng, Y.; Wang, Y.; Ghetti, B.; Hodes, M.E.; and Dlouhy, S.: The weaver gene is alternatively spliced: Cloning and expression of a novel isoform expressed mainly in the cerebellum. Clinical Neuropathology, 15:179, 1996.
Tagliavini, F.; Prelli, F.; Tranchant, C.; Warter, J.M.; Porro, M.; Beavis, R.C.; Perini, F.; Rossi, G.; Giaccone, G.; Piccardo, P.; Ghetti, B.; Bugiani, O.; and Frangione, B.: Biochemical characterization of amyloid peptides in the Alsatian family of Gerstmann-Sträussler-Scheinker disease. Clinical Neuropathology, 15:184-185, 1996.
Ghetti, B.; Farlow, M.R.; Crowther, R.A.; Goedert, M.; Spillantini, M.G.: Hereditary multiple system degeneration with presenile dementia: tau (τ) abnormalities in nerve cells and oligodendroglia. Journal of Neuropathology and Experimental Neurology, 55:608, 1996.
Wei, J.; Hodes, M.; Piva, R.; Wang, Y.; Feng, Y.; Ghetti, B.; Dlouhy, S.: Multiple isoforms of alternatively-spliced GIRK2 transcripts are differentially expressed in murine CNS and testis. Journal of Neuropathology and Experimental Neurology, 55:615, 1996.
Dlouhy, S.; Wei, J.; Feng, Y.; Wang, Y.; Ghetti, B.; Hodes, M.: The murine gene TIAM1 is differentially expressed in mouse brain and developmentally regulated in cerebellar granule neurons. Journal of Neuropathology and Experimental Neurology, 55:615, 1996.
Migheli, A.; Attanasio, A.; Piva, R.; Wei, J.J.; Hodes, M.E.; Dlouhy, S.; Ghetti, B: Modalities of cell death in weaver mutant mice. Journal of Neuropathology and Experimental Neurology, 55:621, 1996.
Giaccone, G.; Frigerio, L.; Pollo, B.; Ghetti, B.; Tagliavini, F.; Bugiani, O.: Topography of phosphorylated tau immunoreactivity in Alzheimer disease, progressive supranuclear palsy and Pick disease. Journal of Neuropathology and Experimental Neurology, 55:634, 1996.
Piccardo, P.; Seiler, C.; Dlouhy, S.; Young, K.; Farlow, M.; Prelli, F.; Frangione, B.; Bugiani, O.; Tagliavini, F.; Ghetti, B.: Proteinase K (PK) resistant prion protein (PRP) isoforms in Gerstmann-Sträussler-Scheinker disease (GSS) F198S. Journal of Neuropathology and Experimental Neurology, 55:636, 1996.
Hutchins, G.D.; Farlow, M.R.; Dlouhy, S.R.; Piccardo, P.; Ghetti, B.: PET study of glucose metabolism in at-risk and affected patients with Gerstmann-Sträussler-Scheinker disease. 43^rd Annual Meeting of The Society of Nuclear Medicine, 1996.
Spillantini, M.G.; Goedert, M.; Crowther, R.A.; and Ghetti, B.: Familial multiple system degeneration with presenile dementia: A hereditary disease with tau-positive neurofibrillary pathology. Abstract of Brain Bank Symposium, June 26, 1996.
Zhang, W.; Ghetti, B.; Lee, W-H.: IGF-I expression in Purkinje cell degeneration (pcd) mutant mice. 10^th International Congress of Endocrinology Volume 1:Abstract#P1-531, p267.
Ghetti, B.; Piccardo, P.; Frangione, B.; Bugiani, O.; Giaccone, G.; Young, K.; Prelli, F.; Farlow, M.R.; Dlouhy, S.R.; Tagliavini, F.: Prion Protein Amyloidosis. The Keio Journal of Medicine 45:345-346, 1996.
Ghetti, B.; Young, K.; Piccardo, P.; Tagliavini, F.; Giaccone, G.; Bugiani, O.; Dlouhy, S.R.; Clark, H.B.: Prion protein (PrP) residue 129 Val in Gerstmann-Sträussler-Scheinker (GSS) disease with mutation PRNP P102L. Abstract at the Prion Disease Symposium, NIH, Tokyo, Japan, July 23, 1996.
Tagliavini, F.; Prelli, F.; Salmona, M.; Giaccone, G.; Ghetti, B.; Bugiani, B.; Frangione, B.; Forloni, G.: PrP peptides and pathogenesis of prion diseases. Neurobiology of Aging, 17:S41, 1996.
Frangione, B.; Perini, F.; Vidal, R.; Tagliavini, F.; Ghetti, B.; Prelli, F.: Alzheimer's and prion diseases: soluble proteins are altered in the brain. Why? Neurobiology of Aging, 17:S41, 1996.
Young, K.; Piccardo, P.; Tagliavini, F.; Giaccone, G.; Bugiani, O.; Dlouhy, S.R.; Clark, H.B.; Ghetti, B.: Prion protein (PrP) residue 129 Val in Gerstmann-Sträussler-Scheinker (GSS) disease with mutation PRNP P102L. Neurobiology of Aging, 17:S42, 1996.
Spillantini, M.G.; Goedert, M.; Crowther, R.A.; Ghetti, B.: Characterization of tau-positive fibrillary pathology in familial multiple system degeneration with presenile dementia. Neurobiology of Aging, 17:S158, 1996.
Ghetti, B.; Piccardo, P.; Seiler, C.; Dlouhy, S.; Young, K.; Prelli, F.; Frangione, B.; Bugiani, O.; and Tagliavini, F.: Prion Protein (PrP) Amyloidosis. Abstracts Satellite Symposium on Prion Diseases, Osaka, Japan, July 29, 1996.
Ghetti, B.; Piccardo, P.; Seiler, C.; Dlouhy, S.; Young, K.; Prelli, F.; Frangione, B.; Bugiani, O.; Tagliavini, F.: Prion Protein (PrP) Amyloidosis. Abstracts of NATO Advanced Research Workshop "Prions and Brain Diseases in Animals and Humans", Ettore Majorana Centre, Erice, Italy, August 19-22, 1996.
Ghetti, B.; Piccardo, P.; Farlow, M.R.; Dlouhy, S.R.; Tagliavini, F.; Giaccone, G.; Bugiani, O.: Abnormally phosphorylated Tau (τ) and prion protein amyloidosis. Society for Neuroscience Abstracts, 22:710, 1996.
Parchi, P.; Capellari, S.; Chen, S.G.; Ghetti, B.; Mikol, J.; Vital, C.; Cochran, E.; Trojanowski, J.Q.; Dickson, D.W.; Petersen, R.B.; Gambetti, P.: Similar posttranslational modifications of the prion protein in familial, sporacid and iatrogenic Creutzfeldt-Jakob disease (CJD). Society for Neuroscience Abstracts, 22:711, 1996.
Wei, J.; Hodes, M.E.; Wang, Y.; Feng, Y.; Dupree, B.; Ghetti, B.; Dlouhy, S.R.: Molecular cloning and characterization of murine GIRK2 and its multiple isoforms. Society for Neuroscience Abstracts, 22:1246, 1996.
Won, L.; Ghetti, B.; Heller, A.: Use of reaggregate tissue culture for examination weaver gene action on the nigrostriatal dopaminergic projection. Society for Neuroscience Abstracts, 22:1649, 1996.
Dlouhy, S.R.; Richter, J.; Stauss, C.; Wei, J.; Hodes, M.E.; Ghetti, B.: Introduction of the weaver gene into the Balb/cJ strain. Society for Neuroscience Abstracts, 22:1649, 1996.
Prelli, F.; Tagliavini, F.; Perini, F,; Porro, M.; Beavis, R. C.; Tranchant, C.; Warter, J.-M.; Katz, E.; Ghetti, B.; Bugiani, O.; Frangione, B.: Biochemical characterization of amyloid peptides in an Alsatian patient with Gerstmann-Sträussler-Scheinker disease: A PRNP codon 117Val mutation. Society for Neuroscience Abstracts, 22:2125, 1996.
Perini, F.; Vidal, R.; Tagliavini, F.; Toso, V.; Ghetti, B.; Frangione, B.; Prelli, F.: PrP27-30 is a normal soluble prion protein fragment released by human platelets. Society for Neuroscience Abstracts, 22:2140, 1996.
Cervenakova, L.; Brown, P.; Piccardo, P.; Cummings, J.L.; Nagle, J.; Vinters, H.V.; Ghetti, B.; Gajdusek, D.C.; and Goldfarb, L.G.: Molecular mechanisms in spongiform encephalopathy: deletion of a 24-bp repeat. Jamaica, 1997.
Ghetti, B.; Murrell, J.; Farlow, M.R.; Crowther, R.A.; Goedert, M.; and Spillantini, M.G.: Molecular neuropathology of a multiple system tauopathy: a chrom-osome 17 linked presenile dementia. Neurology, 48:A356, 1997.
Farlow, M.R.; Murrell, J.; Unverzagt, F.; and Ghetti, B.: Clinical characteristics in a large kindred with familial multiple systems tauopathy linked to chromosome 17. Neurology, 48:A356, 1997.
Murrell, J.; Koller, D.; Foroud, T.; Farlow, M.; and Ghetti, B.: Genetic localization of familial multiple system tauopathy with presenile dementia to chromosome 17. Neurology, 48:A395, 1997.
Piccardo, P.; Seiler, C.; Dlouhy, S.R.; Young, K.; Farlow, M.R.; Tagliavini, F.; and Ghetti, B.: Pathologic prion protein isoforms in Gerstmann-Sträussler-Scheinker disease. Meeting of the Argentine Bovine Spongiform Encephalopathy Consultant Team (ABSECT), April 7-9, 1997.
Dlouhy, S.R.; Verina, T.; Wei, J.J.; Richter, J.; Stauss, C.; Hodes, M.E.; and Ghetti, B.: Genetic strain background influences the phenotypic effects of the mouse weaver gene. Journal of Neuropathology and Experimental Neurology, 56:587, 1997.
Giaccone, G.; Canciani, B.; Piccardo, P.; Tagliavini, F.; Ghetti, B.; Bugiani, O.: Topography of AT8 immunoreactivity in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Journal of Neuropathology and Experimental Neurology, 56:588, 1997.
Piccardo, P.; Tagliavini, F.; Dlouhy, S.R.; Young, K.; Seiler, C.; Rossi, G.; Hill, A.F.; Bugiani, M.; Bugiani, O.; Collinge, J.; Ghetti, B.: An antiserum to residues 95-108 of human PrP detects PrPres in a variety of human and animal prion diseases. Journal of Neuropathology and Experimental Neurology, 56:589, 1997.
Young, K.; Russel, J.A.; Ma, J.M.; Hedley-Whyte, T.E.; Dlouhy, S.R.; Piccardo, P.; Ghetti, B.: Gerstmann-Sträussler-Scheinker (GSS) disease with the prion protein gene (PRNP) P102L mutation and lower motor neuron degeneration. Journal of Neuropathology and Experimental Neurology, 56:596, 1997.
Mirra, S.S.; Gearing, M.; Jones, R.; Evatt, M.L.; Young, K.; Piccardo, P.; and Ghetti, B.: Prion protein (PrP) amyloid coexists with neurofibrillary tangles and Lewy bodies in a patient from a new family of Gerstmann-Sträussler-Scheinker disease (GSS). Journal of Neuropathology and Experimental Neurology, 56:596, 1997.
Wei, J.J.; Dlouhy, S.R.; Ghetti, B.; and Hodes, M.E.: Specific non-polyadenylated transcripts of Girk2 and Tiam1 are present during murine CNS development. Journal of Neuropathology and Experimental Neurology, 56:598, 1997.
Murrell, J.; Koller, D.; Foroud, T.; Goedert, M.; Spillantini, M.G.; Farlow, M.R.; and Ghetti, B.: Gene map of the MSTD (multiple system tauopathy with presenile dementia) region on human chromosome 17q21-22. Journal of Neuropathology and Experimental Neurology, 56:610, 1997.
Giaccone, G.; Canciani, B.; Piccardo, P.; Tagliavini, F.; Bugiani, O.; and Ghetti, B.: Immunohistochemical distribution of phosphorylated tau in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Clinical Neuropathology 16:156, 1997.
Lievens, P.M.J.; Galimberti, C.; Young, K.; Ghetti, B.; Bugiani, O.; Tagliavini, F.: F198S and Q217R mutant prion proteins acquire abnormal properties when expressed in cultured cells. Clinical Neuropathology 16:157, 1997.
Schwartz, N.B.; Szabo, M.; Verina, T.; Wei, J.J.; Dlouhy, S.; Won, L.; Heller, A.; Ghetti, B.: Hypothalamic-pituitary function is unaffected by the weaver (wv) mouse mutation. Biology of Reproduction 56(S1):224, 1997
Ghetti, B.; Murrell, J.; Farlow, M.F.; Crowther, R.A.; Goedert, M.; and Spillantini, M.G.: Molecular pathology of chromosome 17 linked multiple system tauopathy with presenile dementia (MSTD). Brain Pathology 7:1175, 1997.
Piccardo, P.; Tagliavini, F.; Dlouhy, S.R.; Seiler, C.; Rossi, G.; Hill, A.F.; Bugiani, M.; Bugiani, O.; Langeveld, J.P.M.; Collinge, J.; Ghetti, B.: Species and disease specific prion protein (PrP) isoforms are detected by antibodies (abs) raised against a highly conserved mid-region sequence. Brain Pathology 7:1248, 1997.
Mirra, S.S.; Young, K.; Gearing, M.; Jones, R.; Evatt, M.L.; Piccardo, P.; Ghetti, B.: Coexistence of prion protein (PrP) amyloid, neurofibrillary tangles, and Lewy bodies in Gerstmann-Sträussler-Scheinker disease with prion gene (PRNP) mutation F198S. Brain Pathology 7:1379, 1997.
Migheli, A.; Piva, R.; Casolino, S.; Dlouhy, S.R.; Ghetti, B.: Continuous cell cycle activation and apoptosis in weaver mouse cerebellum. Trends in Neurosciences 20:30, 1997.
Gearing, M.; Ghetti, B.; Mirra, S.S.: Regional differences in colocalization of apolipoprotein E (ApoE) with ß-amyloid (Aß) and prion protein (PrP) in Alzheimer's disease (AD) and Gerstmann-Sträussler-Scheinker Disease (GSS). Society for Neuroscience Abstracts 23:538, 1997.
Verina, T.; Dlouhy, S.R.; Wei, J.J.; Fitzpatrick, L.; Stauss, C.; Ghetti, B.: WV-Induced vulnerability of the midbrain dopaminergic neurons is enhanced by the BALB/cJ background. Society for Neuroscience Abstracts 23:631, 1997.
Bales, K.R.; Verina, T.; Ghetti, B.; Dodel, R.C.; Du, Y.; Altstiel, L.; Bender, M.; Miller, D.; Hyslop, P.; Paul, S.M.: Apolipoprotein E alters brain amyloid deposition: Results from the PDAPP X APOE (PDapoE) transgenic mouse. Society for Neuroscience Abstracts 23:1638, 1997.
Weaver, C.L.; Ghetti, B.; Jicha, G.A.; Davies, P.: Immunoaffinity purification of a soluble pool of abnormal tau from Alzheimer's disease and Alzheimer-like neuropathies. Society for Neuroscience Abstracts 23:1642, 1997.
Fox A. P.; Hurley, J.H.; Nucifora, P.G.P.; Nelson, D. J.; Ghetti, B.; Dlouhy, S.; Wei, J.; Feng, Y.; Won, L.; Heller, A.: Altered calcium regulation in weaver heterozygote cerebellar neurons. Society for Neuroscience Abstracts 23:1873, 1997.
Piccardo, P.; Dlouhy, S.R.; Young, K.; Lievens, P.; Bugiani, O.; Tagliavini, F.; Ghetti, B.: Prion proteins in P102L Gerstmann-Sträussler-Scheinker disease (GSS). Society for Neuroscience Abstracts 23:1906, 1997.
Goffredo, D.; Giaccone, G.; Ghetti, B.; Tagliavini, F.; Bugiani, O.: Alzheimer's disease. Patterns of phosphorylated tau immunoreactivity. Societe Francaise De Neuropathologie Reunion, Paris, France, December 1997.
Parchi, P.; Giese, A.; Capellari, S.; Brown, P.; Schulz-Schaeffer, W.J.; Windl, O.; Budka, H.; Julien, J.; Kopp, N.; Poser, S.; Rojiani, A.M.; Streichenberger, N.; Vital, C.; Zerr, I.; Ghetti, B.; Kretzschmar, H.A.; Gambetti, P.: The molecular and clinicopathologic spectrum of phenotypes of sporadic Creutzfeldt-Jakob disease (sCJD). Neurology 50:A336, 1998.
Vidal, R.G.; Calero, M.; Piccardo, P.; Farlow, M.R.; Unverzagt, F.W.; Mendez, E.; Jimenez-Huete, A.; Beavis, R.; Gallo, G.; Ghiso, J.; Frangione, B.; and Ghetti, B.: APOE-e4 homozygosity associated with Aß angiopathy and perivascular tau pathology without neuritic plaques in senile dementia. Neurology 50:A407, 1998.
Wei, J.J.; Hodes, M.E.; Feng, Y.; Ghetti, B.; and Dlouhy, S.R.: Genomic organization of Girk2, a potassium channel gene in mice. Journal of Neuropathology Experimental Neurology 57:486, 1998.
Gearing, M.; Levey, A.I.; Jones, R.; Walton, W.; Shoffner, J.M.; Schmidt, M.L.; Trojanowski, J.Q.; Ghetti, B.; and Mirra, S.S.: Tau cytopathology in a patient with familial early onset dementia. Journal of Neuropathology Experimental Neurology 57:508, 1998.
Verina, T.; Bales, K.; Dodel,R.C.; Du, Y.; Altstiel, L.; Bender, M.; Hyslop, P.; Johnstone, E.M.; Little, S.P.; Cummins, D.J.; Piccardo, P.; Paul, S.; and Ghetti, B.: Lack of apoE gene reduces amyloid formation in transgenic mice overexpressing APPV717F. Journal of Neuropathology Experimental Neurology 57:512, 1998.
Lievens, P.M-J.; Quaglio, E.; Piccardo, P.; Tranchant, C.; Warter, J.M.; Bird, T.; Bugiani, O.; Ghetti, B.; and Tagliavini, F.: Distinctive PrP isoforms in Gerstmann-Sträussler-Scheinker disease with tangles. Journal of Neuropathology Experimental Neurology, 57:517, 1998.
Young, K.; Piccardo, P.; Kish, S.J.; Ang, L.C.; Dlouhy, S.; Ghetti, B.: Gerstmann-Sträussler-Scheinker disease (GSS) with a mutation at prion protein (PrP) residue 212. Journal of Neuropathology Experimental Neurology, 57:518, 1998.
Piccardo, P.; Kish, S.J.; Ang, L.C.; Young, K.; Bugiani, O.; Tagliavini, F.; Dlouhy, S.R.; Ghetti, B.: Prion protein isoforms in the new variant of Gerstmann-Sträussler-Scheinker disease Q212P. Journal of Neuropathology Experimental Neurology, 57:518, 1998.
Lievens, P.M.-J.; Quaglio, E.; Piccardo, P.; Tranchant, C.; Warter, J.M.; Bird, T.; Bugiani, O.; and Ghetti, B.; Tagliavini, F.: PrP isoforms in Gerstmann- Sträussler-Scheinker disease with neurofibrillary tangles. Clinical Neuropathology, 17:157, 1998.
Migheli, A.; Atzori, C.; Piva, R.; Giaccone, G.; Schiffer, D.; Bugiani, B.; Tagliavini, F.; and Ghetti, B.: Increased expression of JNK/SAPK kinases in tauopathies suggests a role in tau phorphorylation. Clinical Neuropathology, 17:159-160, 1998.
Bales, K.R.; Verina, T.; Saura, J.; Dodel, R.C.; Du, Y.; Cummins, D.J.; Piccardo, P.; Ghetti, B.; and Paul, S.M.: Apolipoprotein E and amyloid deposition in the V717F (PDAPP) transgenic mouse. Neurobiology of Aging, 19:S143, 1998.
Dlouhy, S.; Piccardo, P.; Farlow, M.; Short, R.; Young, K.; Lahti, M.; Rentz, C.; and Ghetti, B.: Atypical presenile dementia with kuru-like plaques. Neurobiology of Aging, 19:S171, 1998.
Piccardo, P.; Mirra, S.S.; Young, K.; Gearing, M.; Dlouhy, S.R.; and Ghetti, B.: -synuclein accumulation in Gerstmann-Sträussler-Scheinker disease (GSS) with prion protein gene (PRNP) mutation F198S. Neurobiology of Aging, 19:S172, 1998.
Tagliavini, F.; Quaglio, E.; Piccardo, P.; Tranchant, C.; Warter, J.M.; Bird, T.; Bugiani, O.; Ghetti, B.; and Lievens, P.M.-J.: Distinctive PrP isoforms in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Neurobiology of Aging, 19:S210, 1998.
Giaccone, G.; Goffredo, D.; Canciani, B.; Rossi, G.; Ghetti, B.; Tagliavini, F.; and Bugiani, O.: Topographic distribution of phosphorylated tau in Alzheimer Disease as revealed by AT8 immunohistochemistry. Neurobiology of Aging, 19:S297, 1998.
Ghetti, B.; Piccardo, P.; Lievens, P.M.J.; Young, K.; Pocchiari, M.; Bugiani, O.; Tagliavini,F.; and Dlouhy, S.R.: Phenotypic and prion protein (PrP) heterogeneity in Gerstmann-Sträussler-Scheinker disease (GSS) with proline to leucine mutation at PRNP residue 102. Neurobiology of Aging, 19:S298, 1998.
Prelli, F.; Jiménez-Huete, A.; Vidal, R.; Lievens, P.; Piccardo, P.; Ghetti, B.; Tagliavini, F.; and Frangione, B.: Differential processing of normal and disease-specific isoforms of the human prion protein by endogenous protein by endogenous proteases. Neurobiology of Aging, 19:S299, 1998.
Chiesa, R.; Piccardo, P.; Ghetti, B.; and Harris, D.A.: A transgenic mouse model of a familial prion disease with an insertional mutation. Neurobiology of Aging, 19:S300, 1998.
Russo, C.; Hulette, C.; Kippa, C.F.; Ghetti, B.; Lannfelt, L.; Schettini, G.; Tabaton, M.; Gambetti, P.; and Teller, J.K.: Molecular forms of amyloid ß in subjects with familial Alzheimer's disease. Neurobiology of Aging, 19:S311, 1998.
Verina, T.; Bales, K.; Dodel, R.C.; Du, Y.; Altstiel, L.; Bender, M.; Hyslop, P.; Johnstone, E.M.; Little, S.P.; Cummins, D.J.; Piccardo, P.; Paul, S.; and Ghetti. B.: Reduced amyloid formation in transgenic mice overexpressing APPV717F and Lacking ApoE. Abstracts VIII International Symposium on Amyloidosis, pp 188, 1998.
Vidal, R.; Calero, M.; Piccardo, P.; Méndez, E.; Jiménez-Huete, A.; Beavis, R.; Gallo, G.; Ghiso, J.; Frangione, B.; and Ghetti, B.: Cerebrovascular amyloid Aß angiopathy and perivascular tau pathology without neuritic plaques in a patient carrying the ApoE-e4/e4 genotype. Abstracts VIII International Symposium on Amyloidosis, pp 189, 1998.
Piccardo, P.; Langeveld, J.P.M.; Dlouhy, S.R.; Giaccone, G.; Hill, A.F.; Young, K.; Rossi, G.; Bugiani, M.; Bugiani, O.; Collinge, J.; Tagliavini, F.; and Ghetti, B.: An antibody recognizing an epitope defined by residues 100-108 of human PrP detects pathologic isoforms in human and animal prion diseases. Abstracts VIII International Symposium on Amyloidosis, pp 192, 1998.
Mirra, S.S.; Young, K.; Gearing, M.; Jones, R.; Evatt, M.L.; Piccardo, P.; Ghetti, B.: Prion protein (PrP) amyloid coexists with neurofibrillary tangles (NFT) and lewy bodies (LB) in Gerstmann-Sträussler-Scheinker disease (GSS) with prion protein gene (PRNP) mutation F198S. Abstracts VIII International Symposium on Amyloidosis, pp 193, 1998.
Short, R.A.; Farlow, M.; Piccardo, P.; and Ghetti, B.: Abnormal cerebrospinal fluid beta-amyloid and tau protein in Creutzfeldt-Jakob disease. Annals of Neurology, 44:497A, 1998.
Dlouhy, S.R.; Young, K.; Feng, Y.; Ironside, J.; Kish, S.J.; Ang, L.C.; Hodes, M. E.; Piccardo, P.; Ghetti, B.: New variants D202N and Q212P, of Gerstmann-Sträussler-Scheinker disease (GSS): Genotype-phenotype cor-relation in clustered mutations in the prion protein (PrP) gene (PRNP). The American Journal of Human Genetics, 63:A358, 1998.
Ghetti, B.; Young, Y.; Piccardo, P.; Dlouhy, S.R.; Pahwa, R.; Lyons, K.E.; Koller, W.C.; Ma, M.J.; DeCarli, C.; Rosenberg, R.N.: Gerstmann-Sträussler-Scheinker disease (GSS) with PRNP A117V mutation: Studies of a new family. Society for Neuroscience Abstracts, 24:515, 1998.
Saura, J.; Bales, K.R.; Verina, T.; Petegnief, V.; Piccardo, P.; Ghetti, B.; Paul, S.M.: Effect of apolipoprotein E on amyloid ß 40 and 42 peptide deposition and glial activitation in the V717F hAPP transgenic mouse. Society for Neuroscience Abstracts, 24:728, 1998.
Harkins, A.B.; Won, L.; Heller, A.; Dlouhy, S.; Feng, Y.; Ghetti, B.; Fox, A.P.: Intracellular calcium is elevated in weaver homozygote and heterozygote cerebellar granule cells. Society for Neuroscience Abstracts, 24:829, 1998.
Brady, D R.; Spillantini, M.G.; Goedert, M.; Crowther, R.A.; Murrell, J.R.; Farlow, M.R.; and Ghetti, B.: Clinical-pathologic correlation in familial multiple system tauopathy with presenile dementia. Society for Neuroscience Abstracts, 24:1473, 1998.
Piccardo, P.; Young, K.; William, A.; Kish, S.J.; Ang, L.C.; Bugiani, O.; Tagliavini, F.; Dlouhy, S. R.; Ghetti, B.: Physicochemical properties of prion protein (PrP) in Gerstmann-Sträussler-Scheinker disease (GSS) Q212P. Society for Neuroscience Abstracts, 24:1476, 1998.
Bales, K.R.; Verina, T.; Saura, J.; Dodel, R.C.; Du, Y.; Cummins, D.J.; Piccardo, P.; Ghetti, B.; and Paul, S. M.: Apolipoprotein E and amyloid deposition in transgenic mice overexpressing APPV717F. Society for Neuroscience Abstracts, 24:1502, 1998.
Russo, C.; Saido, T.C.; Hulette, C.; Ghetti, B.; Lippa, C.; Tabaton, M.; Lannfelt, L.; Song, X.; Schettini, G.; Gambetti, P.; Teller, J.K.: Mutated presenilin 1 drives the selective deposition of truncated amyloid ß-peptides in the brain parenchyma. Società Italiana di Neuroscienze, VI Riunione Nazionale, Abstract 76, 1998.
Delisle, M-B.; Murrell, J.R.; Rascol, O.; Soulages, X.; Mohr, M.; Calvas, P.; Descombes, S.; Brefel-Courbon, C.; and Ghetti, B.: Tauopathy in a French family with dementia and supranuclear palsy caused by an Asn279Lys mutation in the tau gene. Neurology, 52:A251, 1999.
Murrell, J.R.; Hake, A.M.; Quaid, K.; Farlow, M.R.; and Ghetti, B.: A novel mutation at 717 in the amyloid precursor protein (APP) gene described in a family with early-onset Alzheimer disease. Neurology, 52:A323, 1999.
Parchi, P.; Capellari, S.; Brown, P.; Sima, A.A.F.; Mikol, J.; Gray, F.; Frosch, M.P.; Trojanowski, J.Q.; Vital, C.; Ghetti, B.; Giese, A.; Kretzschmar, H.A.; and Gambetti, P.: Molecular and clinico-pathologic phenotypic variability in genetic Creutzfeldt-Jakob disease. Neurology, 52:A323, 1999.
Descombes, S.; Murrell, J.R.; Delisle, M-B.; Rascol, O.; Soulages, X.; Mohr, M.; Calvas, P.; and Ghetti, B.: A tauopathy in a French family with hereditary supranuclear palsy and dementia caused by a Asn279Lys mutation in the Tau gene: Clinical, neuropathologic, and molecular genetic studies. Abstracts Fondation Ipsen, Colloques Medecine et Recherche, Fatal Attractions within Neurons, April 12, 1999, Paris, France.
Zolo, P.; Spillantini, M.G.; Crowther, T.; Redi, F.; Guazzelli, M.; Murrell, J.; and Ghetti, B.: Pick disease with glial tau inclusions in the white matter. Journal of Neuropathology Experimental Neurology, 58:546, 1999.
Dlouhy, S.; Feng, Y.; Young, K.; Bird, T.; DeCarli, C.; Hodes, M.E.; Piccardo, P.; and Ghetti, B.: An intron mutation in the prion protein gene (PRNP). Journal of Neuropathology Experimental Neurology, 58:550, 1999.
Piccardo, P.; Dlouhy, S. R.; Young, K.; William, A.; Feng, Y.; Quinn, B.; Dal Canto, M.; Sufit, R.; and Ghetti, B.: Creutzfeldt Jakob disease (CJD) with prion protein gene (PRNP) V210I mutation. Journal of Neuropathology Experi-mental Neurology, 58:550, 1999.
Taratuto, A.; Piccardo, P.; Reich, F.; Sevlever, G.; Schultz, M.; Leuzzi, A.; Ruggiero, M.; Abecassis, G.; Engelmann, M.; Garcia, A.M.; Capellari, S.; Lugaresi, E.; Gambetti, P.; Dlouhy, S.R.; Ghetti, B.: Insomnia in familial Creutzfeldt Jakob disease (FCJD), E200K, with thalamic involvement. Journal of Neuropathology Experimental Neurology, 58:551, 1999.
Gearing, M.; Schultz, A.; Ghetti, B.; and Mirra, S.S.: Neuropathological changes and apolipoprotein E genotype in Alzheimer's Disease (AD) with concomitant Lewy bodies: An alpha-synuclein immunohistochemical study. Journal of Neuropathology Experimental Neurology, 58:552, 1999.
Migheli, A.; Piva, R.; Casolino, S.; Atzori, C.; Dlouhy, S.R.; and Ghetti, B.: Cell cycle alteration precedes Apoptosis in the weaver mouse cerebellum. Journal of Neuropathology Experimental Neurology, 58:556, 1999.
Chiesa, R.; Piccardo, P.; Ghetti, B.; Harris, D.A.: Neurological illness in transgenic mice expressing a prion protein with an insertional mutation. Journal of Neuropathology Experimental Neurology, 58:559, 1999.
Delisle, M.B.; Murrell, J.R.; Uro-Coste, E.; Mohr, M.; Rascol, O.; Soulages, X.; Calvas, P.; and Ghetti, B.: Tauopathy in a French family with dementia and supranuclear palsy caused by an Asn279Lys mutation in the tau gene. Neuropathology and Applied Neurobiology, 25:49, 1999.
Ghetti, B.; Young, K.; Piccardo, P.; Dlouhy, S.R.; Pahwa, R.; Lyons, K.E.; Koller, W.C.; Ma, M.J.; DeCarli, C.; and Rosenberg, R.N.: Gerstmann-Sträussler-Scheinker disease (GSS) with PRNP A117V mutation: Neuropathologic and molecular studies of a new family. Neuropathology and Applied Neurobiology, 25:57, 1999.
Awan, T.; Giaccone, G.; Ghetti, B.; Bugiani, O.; and Tagliavini, F.: The use of 14-3-3 assay as a diagnostic tool for Creutzfeldt-Jakob disease. Clinical Neuropathology, 18:125, 1999.
Bugiani, O.; Murrell, J.R.; Giaccone, G.; Hasegawa, M.; Ghigo, G.; Tabaton, M.; Morbin, M.; Primavera, A.; Carella, F.; Solaro, C.; Grisoli, M.; Savoiardo, M.; Spillantini, M.G.; Tagliavini, F.; Goedert, M.; and Ghetti, B.: A Pro301Ser mutation in tau. Clinical Neuropathology, 18:130, 1999.
Migheli, A.; Atzori, C.; Piva, P.; Giaccone, G.; Schiffer, D.; Bugiani, O.; Tagliavini, F.; and Ghetti, B.: Activation of JNK-p38 MAP kinases is a common event in tauopathies. Clinical Neuropathology, 18:142, 1999.
Murrell, J.R.; Zolo, P.; Spillantini, M.G.; Crowther, R.A.; Goedert, M.; Redi, F.; Pietrini, P.; Guazzelli, M.; and Ghetti, B.: A mutation at codon 389 (G389R) in exon 13 of the Tau gene causes frontotemporal dementia with numerous Pick bodies. Clinical Neuropathology, 18:145, 1999.
Ghetti, B.: Advances in the understanding of hereditary tauopathies. Abstract at the IBC's Eighth Annual Conference on Alzheimer's Disease, May 19-21, 1999.
Lippa, C.F.; Kane, K.; Bird, T.D.; Ghetti, B.; Hulette, C.; Nee, L.E.; Nochlin, D.; Pollen, D.A.; Swearer, J.M.: Familial Alzheimer's Disease: Site of Mutation Influences Clinical Phenotype. Annals of Neurology, 46:453, 1999.
Piccardo, P.; Liepnieks, J.J.; William, A.; Dlouhy, S.R.; Farlow, M.R.; Nochlin, D.; Bird, T.D.; Nixon, R.R.; DeCarli, C.; Bugiani, O.; Tagliavini, F.; Benson, M.; and Ghetti, B.: Primary structure of PrPres in GSS A117V and F198S. Journal of Neuropathology and Experimental Neurology,59:432, 2000.
Ghetti, B.; Piccardo, P.; Chiesa, R.; and Harris, D.A.: Hindlimb paralysis and cerebellar PrP deposits in transgenic mice over-expressing wild-type PrP. Journal of Neuropathology and Experimental Neurology, 59:433, 2000.
Farlow, M.R.; Vakili, S.T.; Murrell, J.; Piccardo, P.; Evans, R.M.; Davis, R.L.; Holohan, P.D.; Lawarence, D.A.; Takao, M.; Benson, M.D.; and Ghetti, B:. Neuroserpin-immunopositive neuronal inclusions in hereditary myoclonic epilepsy with dementia. Journal of Neuropathology and Experimental Neurology 59:464, 2000.
Takao, M.; Piccardo, P.; Laycock, M.; Spillantini, M.G.; Farlow, M.R.; and Ghetti, B.: Diffuse neurodegenerative disease with intraneuronal inclusions. Journal of Neuropathology and Experimental Neurology, 59:464, 2000.
Murrell, J.; Evans, R.M.; Boyer, P.J.; Piccardo, P.; Towfighi, J.; and Ghetti, B.: Alzheimer disease with onset in adolescence due to a novel mutation in presenilin I (L166P). Journal of Neuropathology and Experimental Neurology, 59:466, 2000.
Benson, M.D.; Liepnieks, J.J.; Yazaki, M.; Farlow, M.R.; Vakili, S.T.; Murrell, J.; Piccardo, P.; Evans, R.M.; Takao, M.; and Ghetti, B.: Neuroseprin in hereditary myoclonic epilepsy with dementia. Clinical Neuropathology, 19:146, 2000.
Giaccone, G.; Goffredo, D.; Lussich, S.; Ghetti, B.; Tagliavini, F.; and Ghetti, B.: Topographic distribution of phosphorylated tau in Alzheimer’s disease. Clinical Neuropathology, 19:150, 2000.
Marcon, G.; Atzori, C.; Torta, I.; Simonati, A.; Bugiani, O.; Ghetti, B.; and Migheli, A.: Expression of activated caspase-3 in Alzheimer disease and frontotemporal dementia. Clinical Neuropathology, 19:152, 2000.
Migheli, A.; Atzori, C.; Schiffer, D.; and Ghetti, B.: Caspase-3 activation and apoptosis occur in Gerstmann-Sträussler-Scheinker (GSS) disease. Clinical Neuropathology 19:153, 2000.
Murrell, J.; Piccardo, P.; Evans, R.M.; Boyer, P.J.; and Towfighi, J.; Ghetti, B.: Mutation L166P in Presenilin 1 causes early onset Alzheimer disease. Clinical Neuropathology, 19:154, 2000.
Russo, C.; Saido, T.C.; Ghetti, B.; Teller, J.K.; Tabaton, M.; Gambetti, P.; and Schettini, G.: Identification of N-truncated A-peptides in sporadic and familial Alzheimer’s disease. Clinical Neuropathology, 19:158, 2000.
Parchi, P.; Brown, P.; Capellari, S.; Ghetti, B.; Gibbs, C.J.; and Gambetti, P.L.: Transmission to non-human primates indicates that Kuru as well as the ataxic (VV2) or Kuru-plaque (MV2) variants of sporadic Creutzfeldt-Jakob disease are caused by the same strain of prions. Neurobiology of Aging, 21:S57, 2000.
Hake, A.; Murrell, J.R.; Unverzagt, F.W.; Ghetti, B.; and Farlow, M.R.: Clinical characteristics in a family with early-onset Alzheimer disease caused by a mutation (V717L) in the APP gene. Neurobiology of Aging, 21:S59, 2000.
Farlow, M.R.; Murrell, J.R.; Hulette, C.; and Ghetti, B.: Hereditary lateral sclerosis and Alzheimer disease associated with mutation at codon 261 of the Presenilin 1 (PSI) gene. Neurobiology of Aging, 21:S62, 2000.
Yazaki, M.; Benson, M.D.; Liepnieks, J.J.; Farlow, M.R.; Piccardo, P.; Takao, M.; Murrell, J.R.; and Ghetti, B.: A S52R Mutation in neuroserpin is associated with myoclonic epilepsy and dementia. Neurobiology of Aging, 21:S66, 2000.
Ghetti, B.: Neuropathology of hereditary tauopathies. Neurobiology of Aging, 21:S69, 2000.
Marcon, G.; Atzori, C.; Srinivasan, A.N.; Okazawa, H.; Ghetti, B.; and Migheli, A.: Caspase-3 is activated in Alzheimer disease but not in frontotemporal dementia. Neurobiology of Aging 21:S81, 2000.
Russo, C.; Saido, T.C.; Hulette, C.; Ghetti, B.; Teller, J.K.; Tabaton, M.; Schettini, G.; and Gambetti, P.: Increased presence of amino-terminally-truncated A-peptides in presenlin 1 early-onset familial Alzheimer disease. Neurobiology of Aging, 21:S194, 2000.
Pawlik, M.; Sastre, M.; Kumar, A.; Gallo, G.; Ghetti, B.; Tagliavini, B.; and Levy, E.: Codeposition of cystatin C with amyloid- protein in the brain of Alzheimer’s disease patients. Neurobiology of Aging, 21:S194, 2000.
Harris, D.A.; Chiesa, R.; Drisaldi, B.; Quaglio, E.; Migheli, A.; Piccardo, P.; and Ghetti, B.: A transgenic model of a familial prion disease. Neurobiology of Aging, 21:S209, 2000.
Migheli, A.; Atzori, C.; Srinivasan, A.N.; and Ghetti, B.: Caspase-3 mediates apoptosis in Gerstmann-Sträussler-Scheinker (GSS) disease. Neurobiology of Aging, 21:S266, 2000.
Takao, M.; Hayakawa, I.; Ikeda, E.; Murrell, J.R.; Piccardo, P.; Ghetti, B.; and Koto, A.: Familial presenile dementia with parkinsonism in a Japanese family. Neurobiology of Aging 21:S267, 2000.
Piccardo, P.; Liepnieks, J.J.; William, A.; Dlouhy, S.R.; Bugiani, O.; Tagliavini, F.; Benson, M.D.; and Ghetti, B.: Determination of the amino-terminal cleavage site of PrPres in GSS F198S. Neurobiology of Aging, 21:S268, 2000.
Ghetti, B.: Hereditary tauopathies. Brain Pathology, 10:493, 2000.
Takao, M.; Murrell, J.R.; Benson, M.D.; Yazaki, M.; Piccardo, P.; Davis, R.; Holohan, P.D.; Lawrence, D.A.; Farlow, M.R.; and Ghetti, B.: The Neuroserpin S52R mutation causes progressive myoclonus epilepsy and a wide distribution of intraneuronal neuroserpin deposits in the CNS. Brain Pathology, 10:597, 2000.
Parchi, P.; Capellari, S.; Gibbs, C.J.; Ghetti, B.; Brown, P.; and Gambetti, P.: Transmission to non-human primates indicates that the same strain of prion can be associated with sporadic, familial, and iatrogenic forms of prion disease. Brain Pathology, 10:608, 2000.
Takao, M.; Murrell, J.R.; Giaccone, G.; Evans, R.; Tagliavini, F.; Bugiani, O.; Farlow, M.R.; Heyman, A.; and Ghetti, B.: Neuropathology of early onset familial Alzheimer disease associated with the Presenilin 1 S169L mutation. Brain Pathology, 10:633, 2000.
Rozemuller, A.; Awan, T.; Ghetti, B.; Puoti, G.; Eikelenboom, P.; and Tagliavini, F.: Microglia and complement in the cortex of Creutzfeldt-Jakob disease and comparison with Alzheimer’s Disease. Brain Pathology, 10:658, 2000.
Taratuto, A.; Sevlever, G.; Ghetti, B.; Young, K.; Dlouhy, S.; Schultz, M.; Martinetto, H.; Begue, C.; and Piccardo, P.: Creutzfeldt-Jakob disease (CJD) in Argentina. Brain Pathology, 10:658, 2000.
Adamec, E.; Murrell, J.R.; Takao, M.; Hobbs, W.; Nixon, R.A.; Ghetti, B.; and Vonsattel, J.P.: A P301L tauopathy with prominent argyrophilic, tau-positive, perinuclear rings. Brain Pathology, 10:661, 2000.
Piccardo, P.; Liepnieks, J.J.; William, A.; Dlouhy, S.R.; Bugiani, O.; Tagliavini, F.; Benson, M.; and Ghetti, B.: PrP conformational isomers are present in the variants A117V and F198S of Gerstmann-Sträussler-Scheinker disease. Brain Pathology, 10:671, 2000.
Yazaki, M.; Liepnieks, J.J.; Murrell, J.R.; Farlow, M.R.; Piccardo, P.; Takao, M.; Ghetti, B.; and Benson, M.D.: Only mutated neuroserpin protein accumulates in cytoplasmic inclusions of a recently recognized form of progressive myoclonus epilepsy. Brain Pathology, 10:682, 2000.
Ghetti, B.; Murrell, J.R.; Takao, M.; Goedert, M.; and Spillantini, M.G.: Genotype-phenotype interactions in hereditary tauopathies. Brain Pathology, 10:713, 2000.
Piccardo, P.; Vidal, R.; Calero, M.; Farlow, M.R.; Unverzagt, F.W.; Gomez-Tortosa, E.; Ghiso, J.; Hyman, B.; Frangione, B.; and Ghetti, B.: Dementia associated with Amyloid  angiopathy, tau perivascular pathology and APOE  4 genotype. Brain Pathology, 10:714, 2000.
Tsuboi, Y.; Baker, M.; Hutton, M.; Uitti, R.J.; Rascol, O.; Delisle, M.B.; Reed, L.; Brefel-Courbon, C.; Murrell, J.R.; Ghetti, B.; Yasuda, M.; Komure, O.; Kuno, S.; Arima, K.; Sunohara, N.; and Wszolek, Z.K.: Families with N279K Mutation on the Tau Gene; Clinical, Molecular Genetic and Pathological Studies. Neurology 56 (Suppl. 3) A126, 2001.
Filla A.; Ghetti, B.; Piccardo, P.; De Falco, A.; Pochiari M.; Petraroli, R.; Casali, C.; Orio M.; Caneve G.; Manfredi M.; and De Michele G.: Intrafamilial phenotypic variability in a new Italian kindred with Gerstmann-Sträussler-Scheinker disease with the P102L mutation. Neurology 56 (Suppl. 3) A126, 2001.
Cochran, E.J.; Murrell, J.R.; Fox, J.; Ringman, J.; and Ghetti, B.: A novel mutation in the Presenilin-1 (PS1) gene (A431E) associated with early-onset Alzheimer disease. Journal of Neuropathology and Experimental Neurology, 60:544, 2001.
Delisle, M.B.; Uro-Coste, E.; Rascol, O.; Siani, V.; Piccardo, P.; Takao, M.; Vidal, R.; and Ghetti, B.: A neurodegenerative disease with intranuclear deposits: Clinical and neuropathologic studies. Journal of Neuropathology and Experimental Neurology, 60:514, 2001.
Ghetti, B.; Piccardo, P.; Parisi, J.; Takao, M.; Dlouhy, S.; Cochran, E.J.; and Fox, J.H.: Gerstmann-Sträussler-Scheinker (GSSD) Disease with neurofibrillary tangles and PrP-amyloid plaques: A new family. Journal of Neuropathology and Experimental Neurology, 60:537, 2001.
Miravalle, L.; Murrell, J.R.; Takao, M.; Richardson, R.; Bassett, S.S.; Crain, B.; and Ghetti, B.: Hippocampal pathology in patients with FTDP-17 and a mutation in the intron following exon 10 (+16) of the tau gene. Journal of Neuropathology and Experimental Neurology, 60:548, 2001.
Murrell, J.R.; Miravalle, L.; Foster, N.L.; Albin, R.; Takao, M.; and Ghetti, B.: Early-onset familial Alzheimer disease (AD) from the first American report: A presenilin 1 (PS1) mutation found in descendents. Journal of Neuropathology and Experimental Neurology, 60:543, 2001.
Piccardo, P.; William, A.; Dlouhy, S.R.; Farlow, M.R.; Takao, M.; and Ghetti, B.: Two nonglycosylated prion protein (PrP) isoforms coexist within the same microregions in the brain of some individuals with sporadic Creutzfeldt-Jakob disease (sCJD). Journal of Neuropathology and Experimental Neurology, 60:549, 2001.
Takao, M.; Hayakawa, I.; Ikeda, E.; Koto, A.; Fukuuchi, Y.; Miravalle, L.; Piccardo, P.; Murrell, J.R.; and Ghetti, B.: A novel mutation (G217D) in the Presenlin 1 (PS1) gene associated with familial presenile dementia and parkinsonism in a Japanese family. Journal of Neuropathology and Experimental Neurology, 60:543, 2001.
Vidal, R.; Benson, M.D.; Liepnieks, J.M.; Yazaki, M.; Miravalle, L.; Uro-Coste, E.; Delisle, M.B.; and Ghetti, B.: A neurodegenerative disease with intranuclear protein deposits: Electron microscopic and biochemical studies. Journal of Neuropathology and Experimental Neurology, 60:515, 2001.
Tsuboi, Y.; Uitti, R.J.; Rascole, O.; Delisle, M-B.; Reed, L.; Ghetti, B; Brefel-Courbon, C.; Yasuda, M.; Komure, O.; Kuno, S.; Arima, K.; and Wszolek, Z.K.: Families with N279K mutation on the tau gene (chromosome 17q21)-comparison of clinical, laboratory and pathological features. Journal of the Neurological Sciences 2001;187(Suppl 1):S306.
Vidal, R.; Delisle, M.B.; Liepnieks, J.J.; Uro-Coste, E.; Yazaki, M.; Rascol, O.; Siani, V.; Miravalle, L.; Takao, M.; Piccardo, P.; Calvas, P.; Benson, M.D.; and Ghetti, B.: Cns and systemic deposition of ferritin and iron associated with a novel autosomal dominant neurodegenerative disease. Society for Neuroscience Abstracts, Vol. 27, Program No. 572.14, 2001.
Wszolek, Z.K.; Tsuboi, Y.; Uitti, R.J.; Baker, M.; Hutton, M.; Ghetti, B.; Boeve, B.F.; Brefel-Courbon, C.; Dickson, D.W.; Murrell, J.R.; Arima, K.; Delisle, M.B.; Dysken, M.; Yasuda, M.; Sunohara, N.; Rascol, O. Komure, O.; Heutink, P.; Petersen, R.C. Kuno, S.; Pickering-Brown, S.; Kobayashi, T.; Mizuno, Y.; Relationship between the Extended Tau Haplotype and Clinical Presentation in FTDP-17 Families with Three Most Common Tau Mutations (P301L, +16, and N279K). Neurology 58:A111, 2002.
Ringman, J.M.; Diaz-Olavarrieta, C.; Murrell, J.; Rodriguez, Y.; Ghetti, B.; Paz, F.; Chavez, M.; Kawas, C.: Presenilin-1 mutation carriers attain less education than their non-mutation carrying kin. Neurology 58:A132, 2002.
Ringman, J.M.; Murrell, J.; Rodriguez, Y.; Diaz-OIavarrieta, C.; Haier, R.; Ghetti, B.; Paz, F.; Chavez, M.; Kawas, C.: Choice Reaction Time Increases with Age during the Pre-Clinical Phase in Presenilin-1 Mutation Carriers. Neurology 58:A242-3, 2002
Vidal, R. Delisle, M.B. Takao, M. Miravalle, L. Uro-Coste, E. Liepnieks, J.J. Yazaki, M. Siani, V. Piccardo, P. Calvas, P. Murrell, J.R. Benson, M.D. Rascol, O. and Ghetti, B.: A familial autosomal dominant disease associated with intracytoplasmic and intranuclear ferritin accumulation. Clinical Neuropathology 21:136-137, 2002.
Piccardo, P. Unverzagt, F. William, A. Takao, M. Dlouhy, S. Farlow, M.R. Ghetti, B.: Pathologic prion protein in an asymptomatic carrier of a PRNP mutation. Clinical Neuropathology 21:128-129, 2002.
Tabaton, M. Vitali, A.; Borhi, R. Perry, G. Siedlak, S.L. Giliberto, L. Zaccheo, D. Ghetti, B.: Soluble amyloid -protein is increased in frontotemporal dementia associated with Tau gene mutations. Clinical Neuropathology 21:134-135, 2002.
Filla, A. Ghetti, B. Coppola, B. De Falco, A. Pocchiari, M. Petraroli, R. Casali, C. Orio, M. Caneve, G. Manfredi, M. De Michele, G.: Intrafamilial phenotypic variability in a new Italian kindred with Gerstmann-Sträussler-Scheinker disease with the P102L mutation. Clinical Neuropathology 21:117, 2002.
Byrne, N.P. Ito, M. Takao, M. Miravalle, L. Murrell, J.R. Ghetti, B. Powers, J.M.: A novel form of senile dementia neuropathologically characterized by frontotemporal degeneration and leukoencephalopahy associated with a severe tau deposition predominantly in glia. Journal of Neuropathology and Experimental Neurology 61:460, 2002.
Piccardo P.; Ghetti B.; Chiesa R.; Takao M.; Quaglio E.; Drisaldi B.; Si-Hoe S.L.; Harris D.A.: Uninoculated and scrapie-infected transgenic mice expressing prion protein with a nine octapeptide repeat insertion show distinct neuropathologic features. Journal of Neuropathology and Experimental Neurology 61:491, 2002.
Ghetti, B. Allen, B. Ingram, E. Smith, M.J. Takao, M. Spillantini, M.G. Goedert, M.: Abundant tau filaments and neurodegeneration in mice transgenic for human P301S tau. Journal of Neuropathology and Experimental Neurology 61:484, 2002.
Takao, M. Narain, Y. Spillantini, M.G. Piccardo, P. Murrell, J.R. Vidal, R. Crowther, R.A. Goedert, M. Ghetti, B. Koto, A.:Atypical form of diffuse lewy body disease with onset at 13 years of age. Journal of Neuropathology and Experimental Neurology 61:459, 2002.
Ghetti, B. Molecular basis of phenotypic heterogeneity: Gerstmann-Sträussler-Scheinker syndrome. Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract #WS5-2.
Ghetti, B. Hereditary tauopathies:modeling neuronal pathology in mice transgenic for human P301S Tau. Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract # WS16-2.
Takao, M.; Murrell, J.; Piccardo, P.; Unverzagt, F.W.; Farlow, M.R.; Vidal, R.; Miravalle, L.; Glazier, B.S.; Stuck, J.; Foroud, T.; Ghetti, B. Presenilin 1 mutation P264L associated with presenile dementia, cotton wool plaques and diffuse lewy bodies Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract #PG07.
Miravalle, L.; Murrell, J.R.; Takao, M.; Glazier, B.; Piccardo, P.; Vidal, R.; Ghetti, B. Genetic mutations associated with presenile dementia. Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract # PG53.
Vidal, R.; Piccardo, P.; Miravalle, L.; Takao, M.; Frangione, B.; Ghetti, B. Senile dementia associated with Ab angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE 4 allele Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract #PG54.
Vidal, R.; Delisle, M.B.; Takao, M.; Miravalle, L.; Uro-Coste, E.; Liepnieks, J.J.; Yazaki, M.; Siani, V.; Piccardo, P.; Calvas, P.; Benson, M.D.; Rascol, O.; Ghetti, B. Autosomal dominant neurodegenerative disease associated with accumulation of ferritin. Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract #PG55.
Piccardo, P.; Unverzagt, F.W.; William, A.; Takao, M.; Glazier, B.S.; Dlouhy, S.; DeCarli, C.; Farlow, M.R.; Ghetti, B. In Gerstmann-Sträussler-Scheinker disease, prion protein (PrP) accumulates prior to the onset of clinical symptoms Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract #PK08
Piccardo, P.; Ghetti, B.; Chiesa, R.; Takao, M.; Quaglio, E.; Drisaldi, B.; Si-Hoe, S.L.; Harris, D.A. Characterization of uninoculated and scrapie infected mice expressing PrP with nine octapeptide repeat insertion Seventh European Congress of Neuropathology, Neuropathology 2002. Abstract #PK19.
Foroud, T.; Stuck, J.; Farlow, M.R.; Dlouhy, S.; Ghetti, B.; Conneally, M.P. Indiana Alzheimer Disease Center National Cell Repository. Neurobiology of Aging 23: 81, 2002.
Piccardo, P.; Unverzagt, F.; William, A.; Takao, M.; Glazier, B.; Dlouhy, S.; DeCarli, C.; Farlow, M.; Ghetti, B. Pathologic prion protein is present in the brain of asymptomatic carriers of PRNP mutations associated with Gerstmann-Sträussler-Scheinker disease. Neurobiology of Aging 23: S131, 2002.
Ghetti, B. Histopathology of Tauopathies. Neurobiology of Aging 23: S148, 2002.
Vidal, R.; Delisle, M.B.; Takao, M.; Miravalle, L.; Uro-Coste, E.; Liepnieks, J.J.; Yazaki, M.; Siani, V.; Piccardo, P.; Calvas, P.; Murrell, J.; Benson, M.D.; Rascol, O.; Ghetti, B. A familial adult-onset autosomal dominant neur-odegenerative disease associated with cytoplasmic and intranuclear accumulation of ferritin. Neurobiology of Aging 23: S205, 2002.
Miravalle, L.; Murrell, J.R.; Takao, M.; Glazier, B.; Piccardo, P.; Vidal, R.; Ghetti, B. Genetic mutations associated with presenile dementia. Neurobiology of Aging 23: S322, 2002.
Takao, M.; Piccardo, P.; Murrell, J.; Miravalle, L.; Vidal, R.; Brashear, A.; Foster, N.; Towfighi, J.; Farlow, M. Unverzagt, F.; Koto, A.; Hulette, C.; Conneally, P.M.; Foroud, T.; Cochran, E.; Glazier, B.; Ghetti, B. Neuropathologic heterogeneity associated with presenilin 1 gene mutations . Neurobiology of Aging 23: S417, 2002.
Vitali, A.; Borghi, R.; Piccini, A.; Siedlak, S.; Perry, G.; Smith, M.A.; Giliberto, L.; Zaccheo, D.; Ghetti, B.; Tabaton, M.;. Soluble amyloid β-protein is increased in frontotemporal dementia associated with tau gene mutations. Neurobiology of Aging 23: S193, 2002.
Moehlmann, T.; Winkler, E.; Xia, X.; Edbauer, D.; Murrell, J.; Capell, A.; Kaether, C.; Zheng, H.; Ghetti, B.; Haass, C.; Steiner, H. Proteolytic generation of the intracellular domains of amyloid precursor protein and notch is independent of pathogenic amyloid- peptide production. Neurobiology of Aging 23: S209, 2002.
Chiesa, R.; Quaglio, E.; Drisaldi, B.; Si-Hoe, S.L.; Piccardo, P.; Ghetti, B.; Harris, D.A. Molecular distinction between pathogenic and infectious forms of the prion protein. Neurobiology of Aging 23: S69, 2002.
Benson JD, Kluve-Beckerman B, Little S, Paul S, Takao M, Ghetti B, Benson MD. Role of transthyretin in Alzheimer disease pathology. Abstracts of the 5^th International Symposium on Familial Amyloidotic Polyneuropathy and Other Transthyretin Related Disorders.
Taratuto, A.L.; Seviever, G.; Schultza, M.; Martinetto, H.; Begue, C.; Eicher, S.; Somoza, M.; Ghetti, B.; Piccardo, P. Creutzfeldt-Jakob disease (CJD) in Argentina. International Conference on Transmissible Spongiform Encephalopathies Book of Abstracts. 62, 2002.
Notari, S.; Capellari, S.; Giese, A.; Windl, O.; Piccardo, P.; Baruzzi, A.; Ghetti, B.; Gambetti, P.; Kretzschmar, H.; Parchi, P. pH effect on the PrPSc core fragments generated by proteinase K digestion: implications for the molecular classification of Creutzfeldt-Jakob disease. International Conference on Transmissible Spongiform Encephalopathies Book of Abstracts. 64, 2002.
Parchi, P.; Notari, S.; Capellari, S.; Giese, A.; Windle, O.; Westner, I.; Piccardo, P.; Baruzzi, A.; Kretzschmar, H.; Ghetti, B.; Gambetti, P. Co-occurrence of type 1 and type 2 PrPsc in sporadic Creutzfeldt-Jakob disease: implications for disease classification and surveillance. International Conference on Transmissible Spongiform Encephalopathies Book of Abstracts. 64, 2002.
Chiesa, R.; Piccardo, P.; Quaglio, E.; Drisaldi, B.; Si-Hoe, S.L.; Takao, M.; Ghetti, B.; Harris, D.A. Molecular distinction between pathogenic and infectious forms of the prion protein. International Conference on Transmissible Spongiform Encephalopathies Book of Abstracts. 12, 2002.
Tsuboi, Y.; Baker, M.; Hutton, M.; Uitti, R.J.; Yasuda, M.; Bugiani, O.; Ghetti, B.; Wszolek, Z.K.: Tau Haplotype and Clinical Features of FTDP-17 Families with P301S Tau Mutation. Movement Disorders 1107, 2002.
Ghetti, B.; Tsuboi, Y.; Wszolek, Z.K.; Delisle, M.B.; Dickson, D.W.; Comparison of the neuropathology of two unrelated individuals with the N279K mutation in the Tau gene. Movement Disorders 17:S249, 2002.
Ghetti, B. Pathology of tauopathies. Movement Disorders 17:S5-S6, 2002.
Harris, D.A.;Stewart, R.S.; Drisaldi, B.; Adles, C. Stewart, L.R.; Quaglio, E.; Biasini, E.; Fioriti, L.;: Chiesa, R.; Piccardo, P.; and Ghetti, B: Biosynthesis and metabolism of wild-type, mutant, and transmembrane PrP Abstract Book Keystone symposia: Molecular aspects of Transmisssible Spongiform Encephalopathies (Prion Diseases) p 35, 2003.
Azzarelli, B.; Miravalle L.; Olson J.; Ghetti B.; Biller J.; Vidal R. CADASIL: A familial form of cerebrovascular disease leading to dementia. Indentification of two new families and a novel mutation. Neurology 60:A368-A369, 2003.
Rascol O, Goizet C, Labauge P, Delisle MB, Vidal R, Calvas P, Ghetti B. A novel autosomic dominant movement disorder with intranuclear ferritin-containing inclusions. Neurology 60:A284, 2003.
Murrell J, Behm A, Takao M, Ross J, Spillantini MG, Crowther RA, Grahame N, Goedert M, Ghetti B. Neurodegeneration and phenotypic changes in a human tau P301S transgenic mouse model. Neurology 60:A310, 2003.
Murrell JR, Faber K, Alonso ME, Rasmussen A, Varpetian A, Macias MA, Cochran E, Gambetti P, Castellani RJ, Bauserman SC, Foroud T, Vidal R, Miravalle L, Ghetti B, Ringman JM. The A431E Presenilin 1 gene mutation associated with familial Alzheimer disease in individuals of Mexican descent: evidence for a founder effect. Journal of Neuropathology and Experimental Neurology 62:543, 2003.
Yamaguchi K, Miravalle L, Piccardo P, Murrell JR, Foroud T, Vidal R, Unverzagt FW, Farlow MR, Ghetti B. Pheotypic variability associated with the Presenilin 2 N141I mutation in individuals of Volga-German descent. Journal of Neuropathology and Experimental Neurology 62:543, 2003..
Hattab EM, Murrell JR, Yamaguchi K, Unverzagt FW, Foroud T, Miravalle L, Takao M, Hullette C, Vidal R, Farlow MR, Ghetti B. Widespread Aβ angiopathy, cotton wool plaques and pyramidal tract degeneration are the main neuropathologic features associated with the V261F mutation in the Presenilin 1 gene. Journal of Neuropathology and Experimental Neurology 62:543, 2003.
Bugiani O, Giaccone G, Capobianco R, Tagliavini F, Ghetti B. Alzheimer disease (AD): AT8 recognizes degenerating ectopic neurons and astrocytes in the subcortical white matter. Journal of Neuropathology and Experimental Neurology. 62:547, 2003.
Delisle MB, Haik S, Uro-Coste E, Peoc’h K, Puel M, Revesz T, Piccardo P, Hauw JJ, Duyckaerts C, Laplanche JL, Ghetti B. Gerstmann-Sträussler-Scheinker disease presenting as corticobasal degeneration. Journal of Neuropathology and Experimental Neurology 62:548, 2003.
Lee J, Piccardo P, Wilson JA, Fisher M, William A, Ghetti B. Creutzfeldt Jakob disease with prolonged course and Kuru plaques. Journal of Neuropathology and Experimental Neurology 62:549, 2003.
Vidal R, Azzarelli B, Miravalle L, Olson J, Nukes T, Biller J, Ghetti B. CADASIL in two North American Causcasian families. Journal of Neuropathology and Experimental Neurology 62:568, 2003.
Ghetti B, Dickson D, Rascol O, Tsuboi Y, Murrell JR, Wszolek Z, Delisle MB. Diffuse loss of myelin in FTDP-17 associated with mutation N279K in the Tau gene. Journal of Neuropathology and Experimental Neurology 62:583 , 2003.
Bugiani O, Giaccone G, Capobianco R, Tagliavini F, Ghetti B. Alzheimer disease (AD): AT8 recognizes degenerating ectopic neurons and astrocytes in the subcortical white matter. Clinical Neuropathology 22:142, 2003.
Gemignani A.;Pietrini P.;Palagini L.; Guazzelli M. Zolo P.;Ghetti B.: Sleep eeg and brain metabolism abnormalities in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP17) associated to the tau gene mutation G389R. Società Italiana di Neuroscience, Pisa 26-28 Settembre, pg 46 (ID: 377).
Ghetti B, Murrell JR, Epperson FR, Farlow MR, Goedert M, Spillantini MG. Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP-17) Associated with the Exon 10 +3 Mutation in the Tau gene. Abstracts, XVth International Congress of Neuropathology. Pg S55, 2003.
Ghetti B, Takao M, Murrell JR, Benson MD, Yazaki M, Glazier BS, Epperson F, Piccardo P, Davis R, Holohan PD, Lawrence DA, Farlow MR. Neuroserpin Encephalopathy Associated with the PI12 S52R Mutation. Abstracts, XVth International Congress of Neuropathology. Pg S112, 2003.
Ghetti B, Piccardo P, Clark HB. Gerstmann-Sträussler-Scheinker Disease Associated with the PRNP P102L-129V Haplotype. Abstracts, XVth International Congress of Neuropathology. Pg S149, 2003.
Di Fede G, Giaccone G, Mangieri M, Limido L, Suardi S, Ghetti B, Bugiani O, Tagliavini F. The epsilon isoform of 14.3.3 is present in amyloid deposits of Gerstmann-Sträussler-Scheinker disease. Abstracts, XVth International Congress of Neuropathology. Pg S150, 2003.
Roher A, Esh C, Brune D, Lopez J, Ghetti, B. The Human Amyloid-beta Precursor Protein770 Mutation 717 ValPhe Generates Longer than A42 Peptides and Flocculent Amyloid Aggregates. Abstracts, XVth International Congress of Neuropathology. 2003.
Murrell J, Greally J, Behm A, Spillantini MG, Crowter RA, Grahame N, Goedert M, Ghetti B. Neurodegeneration in a human Tau P301S transgenic mouse model. Abstracts, XVth International Congress of Neuropathology. 2003.
Parchi P, Capellari S, Piccardo P, Farlow MR, Powers J, Dickson DW, Gambetti P, Ghetti B. Clinico-pathologic and molecular characterization of novel human sporadic TSE subtypes. Abstracts, XVth International Congress of Neuropathology. 2003.
Vidal, R.; Delisle, M.B.; Takao, M.; Uro-Coste, E.; Calvas, P.; Benson, M.D.; Miravalle, L.; Rascol, O.; Ghetti, B. Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a TC insertion in exon 4 of the Ferritin Light Polypeptide (FTL) gene. Neurology 62:A177, 2004.
Wszolek, Z.K.; Baba, Y.; Woodruff, B.K.; Uitti, R.J.; Baker, M.C.; Hutton, M.L.; Dickson, D.W.; Ghetti, B.; Murrell, J.R.; Boeve, B.F.; et al. Relationship between the extended tau haplotype and clinical presentation in FTDP-17 families with four Tau mutations (P301L, +16, N279K and P301S). Neurology 62:A510, 2004.
Chiesa, R.; Piccardo, P.; Nowoslawski, L.; Dossena, S.; Roth, K.A.; Ghetti, B.; Harris, D.A. BAX deletion rescues neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease. Abstracts of Prion 2004 Meeting. Paris, France, May 24-28.
Ghetti, B.; Murrell, J.R.; Epperson, F.; Farlow, M.R.; Goedert, M. Clinical, pathologic and genetic studies of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) associated with the exon 10+3 mutation in the Tau gene. Movement Disorders 19:S338, 2004.
Baba, Y.; Uitit, R.J.; Dickson, D.W.; Wszolek, Z.K.; Bird, T.; Ghetti, B. A family with atypical parkinsonism and diffuse leukoencephalopathy. Movement Disorders 19:S424, 2004.
Yamaguchi, K.; Ghetti, B.; Piccardo, P.; Epperson, F.; Miravalle, L.; Farlow, M.R. Clinical, neuropathologic and molecular genetic studies on Gerstmann-Sträussler-Scheinker disease (F198S-V129). Movement Disorders 19:S431, 2004.
Castellani, R.J.; Fortino, A.E.; Common, R.; Perry, G.; Ghetti, B.; Smith, M.A. Calcofluor stains amyloid-beta deposits. Journal of Neuropathology and Experimental Neurology 63:524, 2004.
Yamaguchi, K.; Cochran, E.J.; Murrell, J.R.; Polymeropoulos, M.H.; Shannon, K.M.; Goedert, M.; Ghetti, B. Clinical, molecular genetic and neuropathologic studies of an individual with the A53T mutation in Alpha-synuclein. Journal of Neuropathology and Experimental Neurology 63:526, 2004.
Yamaguchi, K.; Piccardo, P.; Tagliavini, F.; Bugiani, O.; Giaccone, G.; Epperson, F.; Miravalle, L.; Farlow, M.R.; Murrell, J.R.; Gearing, M.; Dlouhy, S.R.; Mirra, S.S.; Ghetti, B. Apha-synuclein deposits in the substantia nigra of individuals with Gerstmann-Sträussler-Scheinker disease (F198S-129V). Journal of Neuropathology and Experimental Neurology 63:527, 2004.
Ghetti, B.; Miravalle, L.; Yamaguchi, K.; Epperson, F.; Murrell, J.R.; Perkins, T.; Hui, S.; Farlow, M.R.; Piccardo, P.; Dlouhy, S.R. Role of the polymorphism at codon 129 of the Prion protein gene in the phenotypic expression of Gerstmann-Sträussler-Scheinker disease associated with the F198S mutation. Journal of Neuropathology and Experimental Neurology 63:524, 2004.
Boyer, P.J.; Hargrave, K.R.; Scott, K.; Piccardo, P.; Murrell, J.R.; Towfighi, J.; Ghetti, B. Spastic paraparesis is an important clinical feature of the L166P Presenilin 1 mutation in familial Alzheimer disease. Journal of Neuropathology and Experimental Neurology 63:524, 2004.
Ghetti, B.; Piccardo, P.; Miravalle, L.; Vidal, R.; Cochran, E.J.; Towfighi, J.; Boyer, P.; Murrell, J.R.; Farlow, M.R.; Koto, A.; Takao, M. Cotton wool plaques in familial Alzheimer disease with Presenilin 1 mutations. Clinical and neuropathologic heterogeneity. Journal of Neuropathology and Experimental Neurology 63:524, 2004.
Miravalle, L.; Ghetti, B.; Calero, M.; Rentz, C.A.; Richardson, R.M.; Takao, M.; Vidal, R. Cotton wool plaques associated with a novel mutation in the Presenilin 1 gene(V261I): Immunohistological, genetic and biochemical studies. Neurobiology of Aging. 25 S2:S157, 2004.
Boeve, B.F.; Tremont, I.W.; Waclawik, A.J.; Murrell, J.; Hermann, B.; Jack, C.R.; Smith, G.E.; Knopman, D.S.; Nair, A.R.; Lindor, N.; Koppikar, V.; Ghetti, B. Longitudinal characterization of two siblings with frontotemporal dementia associated with the S305N Tau mutation. Neurobiology of Aging. 25 S2:S451, 2004.
Murrell, J.; Tremont-Lukats, I.W.; Waclawik, A.J.; Lindor, N.; Ghetti, B.; Boeve, B.F. Genetic analyses of a family with frontotemporal dementia. Neurobiology of Aging. 25 S2:S517, 2004.
Vidal, R.; Ghetti, B.; Delisle, M.B.; Rascol, O.; Perry, G.; Smith, M.A. Oxidative damage in ferritin-induced neurodegeneration. Neurobiology of Aging. 25 S2:S544, 2004.
Spina, S.; Kareken, D.; Unverzagt, F.W.; Murrell, J.R.; Epperson, F.; Goedert, M.; Spillantini, M.; Farlow, M.R.; Ghetti, B. Anatomical substrate of behavioral dysfunction in the early stages of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Society for Neuroscience 34^th Annual Meeting, San Diego (CA), 226.7, 2004.
Ringman, J.M.; Thompson, M.; Murrell, J.R.; Rodriquez, Y.; Chavez, M.; Diaz-Olavarrieta, C.; Macias-Islas, M.A.; Ghetti, B.; Kawas, C.H. Early MMSE Changes in Presenilin-1 mutation carriers. Neurology. Suppl 1 64:A363, 2005.
Hake, A.; Farlow, M.; Farlow, E.; Takao, M.; Piccardo, P.; Spina, S.; and Ghetti, B. Diffuse Lewy Body Disease Clinically Resembling Multiple System Atrophy. Abstracts of the 7^th International Conference AD/PD 2005, Sorrento, Italy, 2005.
Ghetti, B.; Piccardo, P.; Murrell, J.R.; and Vidal, R. Neuropathology at the crossroads of neuropsychiatry and molecular genetics. Neuropathology 25 (Supp):40, 2005
Takao, M.; Murrell, J.R.; Hake, A.M.; Yamaguchi, K.; Miravalle, L.; Glazier, B.S.; Piccardo, P.; Unverzagt, F.; Farlow, M.; and Ghetti, B. Neuropathologic phenotype of Alzheimer disease associated with Presenilin 1 gene Y115C and M146L mutations. Neuropathology 25 (Supp):163, 2005.
Ghetti, B.; and Takao, M. Deciphering presenile dementia. Abstracts 46^th Annual Meeting Societas Neurologica Japonica, Pg 43, 2005.
Miravalle, L.; Calero, M.; Takao, M.; Ghetti, B.; and Vidal, R. Amino-terminally truncated Aβ peptide species are the main constituent of cotton wool plaques. Journal of Neuropathology and Experimental Neurology. 64:441, 2005.
Miravalle, L.; Piccardo, P.; Yamaguchi, K.; Perkins, T.; Hui, S.; Vidal, R.; and Ghetti, B. Role of the APOE genotype on the phenotypic expression and parenchymal amyloid-β peptide deposition in Gerstmann-Sträussler-Scheinker disease associated with the PRNP F198S mutation. Journal of Neuropathology and Experimental Neurology. 64:447, 2005.
Gnezda, A.; Behm A.; Greally, J.; Grahame, N.; Ghetti, B.; and Murrell, J.R. Characterization of a transgenic mouse expressing human P301S Tau. Journal of Neuropathology and Experimental Neurology. 64:471, 2005.
Spina, S.; Farlow, M.R.; Unverzagt, F.W.; Ghetti, B.; and Murrell, J.R. Multiple system tauopathy with presenile dementia (MSTD): does the MAPT haplotype influence the clinical phenotype? Journal of Neuropathology and Experimental Neurology. 64:449, 2005.
Spina, S.; Murrell, J.R.; Gearing, M.; Levey, A.; Mirra, S.; Yamaguchi, K.; Ghett,i B.; and Lah, J. Severe frontotemporal glial pathology and mild hippocampal degeneration associated with the P301L MAPT mutation: study of a previously unreported family. Journal of Neuropathology and Experimental Neurology. 64:434, 2005.
Spina, S.; Piccardo, P.; Takao, M.; Yamaguchi, K.; Foroud, T.; and Ghetti, B. Occurrence of α-synuclein deposition in four-repeat tauopathies versus Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 64:434, 2005.
Takao, M.; Piccardo, P.; Farlow, M.R.; Murrell, J.R.; Unverzagt, F.W.; Yamaguchi, K.; Glazier, B.S.; Epperson, F.; Bigio, E.; DeCarli, C.; and Ghetti, B. Gerstmann-Sträussler-Scheinker disease associated with the PRNP A117V-129V mutation: Neuropathology of an asymptomatic gene carrier and five clinically affected individuals from a family. Journal of Neuropathology and Experimental Neurology. 64:433, 2005.
Takao, M.; Murrell, J.R.; Yamaguchi, K.; Unverzagt, F.W.; Glazier, B.S.; Farlow, M.R.; Grafman, J.; and Ghetti, B. Neuropathologic heterogeneity of Pick’s disease. Journal of Neuropathology and Experimental Neurology. 64:449, 2005
Vidal, R.; Su, Y.; Richardson, R.M.; Widel, M.; Miravalle, L.; and Ghetti, B. Intranuclear inclusions and cytoplasmic aggregates in transgenic mice expressing a c-terminal mutant of the ferritin light polypeptide gene. Journal of Neuropathology and Experimental Neurology. 64:470, 2005.
Vidal, R.; Su, Y.; Gao, X.; Richardson, R.M.; Miravalle, L.; and Ghetti, B. Identification of aggregate interacting proteins and proteasome involvement in transgenic mice expressing a c-terminal mutant of the ferritin light polypeptide gene. Journal of Neuropathology and Experimental Neurology. 64:449, 2005.
Takao, M.; Murrell, J.R.; Yamaguchi, K.; Unverzagt, F.W.; Glazier, B.S.; Farlow, M.R.; Grafman, J.; and Ghetti, B. Neuropathologic heterogeneity of Pick’s disease. Astrocytic tau and neuronal α-synuclein deposits. 8^th European Congress of Neuropathology, Neuropathology 2005, June 25-28, 2005, Amsterdam, The Netherlands.
Spina, S.; Miravalle, L.; Yamaguchi, K.; Murrell, J.R.; and Ghetti, B. Coexistent Alzheimer disease (AD) and frontotemporal dementia associated with exon 10+16 MAPT mutation in an individual carrying the Apolipoprotein E (APOE) ε4/ε4 genotype. 8^th European Congress of Neuropathology, Neuropathology 2005, June 25-28, 2005, Amsterdam, The Netherlands.
Spina, S.; Murrell, J.R.; Gearing, M.; Levey, A.; Mirra, S.; Yamaguchi, K.; Ghetti, B.; and Lah, J. Severe frontotemporal glial pathology and mild hippocampal degeneration associated with the P301L MAPT mutation: study of a previously unreported family. 8^th European Congress of Neuropathology, Neuropathology 2005, June 25-28, 2005, Amsterdam, The Netherlands.
Takao, M.; Piccardo, P.; Farlow, M.R.; Murrell, J.R.; Unverzagt, F.W.; Yamaguchi, K.; Epperson, F.; Bigio, E.; DeCarli, C.; and Ghetti, B. Gerstmann-Sträussler-Scheinker disease associated with the PRNP A117V-129V mutation: Neuropathology of an asymptomatic gene carrier and five clinically affected individuals. 8^th European Congress of Neuropathology, Neuropathology 2005, June 25-28, 2005, Amsterdam, The Netherlands.
Ghetti, B.; Boeve, B.F.; Tremont-Lukats, I.W.; Waclawik, A.J.; Hermann, B.; Shiung, M.M.; Smith, G.E.; Nair, A.R.; Lindor, N.; Koppikar, V.; Murrell, J.; and Jack, C.R. Jr. Frontotemporal dementia associated with the S305N tau mutation. 8^th European Congress of Neuropathology, Neuropathology 2005, June 25-28, 2005, Amsterdam, The Netherlands.
Ingelsson, M.; Russ, C.; Ramasamy, K.; Orne, J.; Skoglund, L.; Raju, S.; Growdon, J.H.; Frosch, M.P.; Ghetti, B.; Brown Jr, R.H.; Irizarry, M.C.; Hyman, B.T. Characterization of tau in human frontal cortex on a neuropathological cohort of tauopathies. Society for Neuroscience 360.9, 2005.
Vidal, R.; Su, Y.; Richardson, R.; Widel, M.; Miravalle, L.; Ghetti, B. Over-expression of a C-terminal mutant of the ferritin light polypeptide gene in transgenic mice results in the accumulation of intranuclear and intracytoplasmic ferritin aggregates Society for Neuroscience 903.4, 2005.
Miravalle, L.; Calero, M.; Takao, M.; Roher, A.; Ghetti, B.; Vidal, R. Characterization of the Aβ peptide species present in cotton wool plaques Society for Neuroscience 581.1, 2005.
Boeve BF, Shiung MM, Jack CR, Knopman D, Smith G, Ivnik R, Hutton M, Tremont-Lukats I, Waclawik A, Murrell J, Koppikar V, Ghetti B, Petersen, R. Changes in the rate of functional, clinical, and radiologic progression in FTDP-17 associated with lithium administration. J Neurol Sci 2005;238(suppl 1):S279.
Tabaton, M.; Piccini, A.; Zanusso, G.; Borghi, R.; Noviello, C.; Monaco, S.; Russo, R.; Gelati, M.; Giordano, R.; Zambenedetti, P.; Russo, C.; Ghetti, B. A cerebellar variant of Alzheimer’s disease caused by a novel Presenlin 1 S170F mutation. Neurology 66:A280, 2006.
Spina, S.; Murrell, J.; Kareken, D.; Unverzagt, F.; Farlow, M.; Ghetti, B. Progression of brain atrophy correlates with impaired performance on selective cognitive functions in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Neurology 66:A55, 2006.
Boeve, B.F.; Shiung, M.M.; Jack, C.R.; Knopman, D.S.; Smith, G.E.; Hutton, M.; Murrell, J.; Koppikar, V.; Ghetti, B.; Petersen, R.C. Changes in the rate of clinical and radiologic progression in FTDP-17 associated with lithium administration. Neurology 66:A57, 2006.
Spina, S.; Murrell, J.; Bermingham, N.; Sweeney, B.; Yoshida, H.; Crowther, A.; Goedert, M.; Keohane, C.; Ghetti, B. Early-onset frontotemporal dementia and parkinsonism associated with the novel G335S mutation in Tau. 5^th International Conference on Frontotemporal Dementias, San Francisco (CA), 2006. Abstract 41.
Spina, S.; Murrell, J.R.; Kareken, D.A.; Unverzagt, F.W.; Farlow, M.R.; Ghetti, B. Progression of brain atrophy correlates with changes in performances on selective cognitive functions in FTDP-17T. 5^th International Conference on Frontotemporal Dementias, San Francisco (CA), 2006. Abstract 88.
Spina, S.; Murrell, J.R.; Farlow, M.R.; Ghetti, B. Clinical symptoms and brainstem pathology in FTDP-17T associated with the exon 10+3 intronic Tau mutation. 5^th International Conference on Frontotemporal Dementias, San Francisco (CA), 2006. Abstract 103.
Murrell, J.R.; Vidal, R.; Spina, S.; Barabair, N.A.; Barbeito, A.G.; Farlow, M.R.; Grafman, J.; Ghetti, B. A mutation (R433W) in the Granulin gene is associated with familial frontotemporal dementia – motor neuron disease (FTD-MND). 5^th International Conference on Frontotemporal Dementias, San Francisco (CA), 2006. Abstract 111.
Ghetti, B.; Kepe, V.; Murrell, J.R.; Farlow, M.R.; Epperson, F.; Bresjanac, M.; Repovs, G.; Smid, L.M.; Popovic, M.; Petric, A.; Huang, S-C.; Small, G.W.; Satyamurthy, N.; Phelps, M.E.; Barrio, J.R. Visualization of prion pathology in the living brain of Gerstmann-Sträussler-Scheinker disease patients using [18F0FDDNP PET. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S9.
Spina, S.; Murrell, J.; Kareken, D.; Unverzagt, F.; Farlow, M.; Ghetti, B. Progression of Brain Atrophy correlates with Impaired Performance on Selective Cognitive Functions in FTDP-17T. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S17.
Bermingham, N.; Spina, S.; Murrell, J.; Sweeney, B.; Ghetti, B. Keohane, C. A young man with frontotemporal dementia and Parkinsonism linked to chromosome 17, associated with a new Tau mutation (G335S). XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S44.
Murrell, J.; Gnezda, A.; Green, A.; Greally, J.; Grahame, N.; Ghetti, B. Pathology of a transgenic mouse expressing human P301S tau. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S44.
Murrell, J.; Schweitzer, K.; McClintick, J.; Decker, E.; Spina, S.; Wang, M.; Edenberg, H.; Ghetti, B. Gene expression and proteomic profiles of FTDP-17: preliminary analyses. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S45.
Spina, S.; Murrell, J.R.; Farlow, M.R.; Ghetti, B. Clinical symptoms and brainstem pathology in FTDP-17 associated with the exon 10+3 intronic Tau mutation. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S46.
Gearing, M.; Johnson, T.M.; Murrell, J.R.; Ghetti, B. Pick disease with overlapping neuropathologic features of progressive supranuclear palsy and extensive glial pathology. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S50.
Vidal, R.; Miravalle, L.; Piccardo, P.; Perkins, T.; Hui, S.; Yamaguchi, K.; Ghetti, B. Aβ(N-42) peptides are co-deposited with PrP amyloid in a subset of individuals with GSS PRNP F198S. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S53.
Vidal, R.; Su, Y.; Richardson, R.; Widel, M.; Miravalle, L.; Ghetti, B. Hereditary ferritinopathy intranuclear accumulation of SDS-insoluble ferritin in FTL498499INSTC transgenic mice. XVI International Conference of Neuropathology, San Francisco (CA), 2006. Brain Pathology 2006;16:S165.
Ghetti, B. Gerstmann-Sträussler-Scheinker disease (GSS) and prion protein cerebral amyloid angiopathy (PrP-CAA). Prion 2006, Torino, Italy, pg. 47.
Piccardo, P.; King, D.; Ghetti, B.; Manson, J.C.; Barron, R.M. Deposition of PrP amyloid in the absence of transmissible disease. Prion 2006, Torino, Italy, pg. 60.
Farinazzo, A.; Zanusso, G.; Piccardo, P.; Ferrari, S.; Fasoli, E.; Gelati, M.; Fiorini, M.; Rissuto, N.; Monaco, S.; Ghetti, B. Two-dimensional analysis of proteinase K-resistant prion protein in GSS P102L mutation. Prion 2006, Torino, Italy, pg. 201.
Ferrari, S.; Fasoli, E.; Zanusso, G.; Gelati, M.; Ghetti, B.; Monaco, S. Immunocytochemistry and immunoelectron microscopy of PrP amyloid plaques in human prion disorders. Prion 2006, Torino, Italy, pg. 244.
Piccardo, P.; King, D.; Campbell, S.; Ghetti, B.; Manson, J.C.; Barron, R.M. Deposition of PrP amyloid in the absence of transmissible disease. Prion 2006, Torino, Italy, pg. 271.
Ghetti, B.; Kepe, V.; Bresjanac, M.; Huang, S.; Small, G.W.; Satyamurthy, N.; Farlow, M.R.; Epperson, F.; Repovs, G.; Smid, L.M.; Popvic, M.; Petric, A.; Phelps, M.E.; Barrio, J.R. Visualization of PrP-amyloid in Gerstmann-Sträussler-Scheinker (GSS) disease with [F-18]FDDNP. Prion 2006, Torino, Italy, pg. 364.
Ghetti, B.; Spina, S.; Miravalle, M.; Murrell, J.R.; Farlow, M.R. Deciphering Hereditary Presenile Dementia. Proceedings of the British Neuropathological Society 2007.
Ghetti, B.; Spina, S.; Murrell, J.R.; Huey, E.D.; Pietrini, Ps.; Sweeney, B.; Wasserman, E.M.; Keohane, C.; Goedert, M.; Farlow, M.R.; Grafman, J. In vivo and postmortem clinicoanatomical correlations in FTDP-17. Proceedings of the Eighth International Conference AD/PD 2007.
Tabaton, M.; Mangerini, R.; Tamagno, E.; Ghetti, B.; D’Adamio, L.; Piccini, A.; Borghi, R. Preseniln 1 gene mutations increase the expression and the activity of BACE1. Proceedings of the Eighth International Conference AD/PD 2007.