BIBL XO&UPHY _.- MXCHAEL HEIDELBERGER 1. On the nature of certain sodium-uranium compounds. Heidelberger. J.Am.Chern. SOC. 31 , 1040 (1909) F.J.Metzger and Michael 2. The volumetric determination of cerium in c.eritc qnd monazite. FbJIMetzger and Michael Heidelberger. 3. Dissertition: Phthaloner in the quinazolone series, and thtir derivatives. Columbia University, Mew York, 1911. 4. Researches on quinazolines (28" paper). On 4-quinazoline-2tphthalones and certain of their derivatives. Marston T. Bogert and Michael Heidelberger. J.Am.Chem. SOC., 34, A83 (1912) Heidelberger. ibid., 32, 642 (1910) 5- Zur Ktnntniss des Cyclo-octatetraens. Richard Willsthter and Michael Ber. d. Deut. Chem. Ges., 46, 517' (1913) 6. Mercury derivatives of aromatic amines. aminophcnylmercuric compounds. ?roc. Nat. Acad. Sci., 1, 195 (1915) On a new group of beettricidal SUb6t8nCt?S obtained from hcxamtthylcnetetrunine~ Walter A. Jacobs-and Michael Heidelberger. primary and secondary p=atninophenylmercuric cempounds, W.A.Jocobs and b4ichael Heidclbesger. J. Biol. Chern., 20,, 513 \1915) The quaternary salts of hexanothylenet.etruine. I.. Substituted benzyA halides and the hcx~tthylenetetruniniwn salts deri'ved 11. Monohalogenacetyl-btnzy1amines and their hexomethylcnetetraminium salts. 111. Monohalogenocetylated aromatic amines and their hexamethylenetetraminium IV. Monohalogenocetylated simple amines, ureas, and urethanes, and the hexa- V. I~lenohalogenacety1 derivatives of aminpalcohols and the hcxamethylene- VI. Halogenethyl ethers and esters and their hexamethylenetetraminium salts. VII. Halogen derivatives of aliphatic-aromatic ketones and their hexamethylene- VIII. Miscellaneous substances containing aliphatically bound halogen, and the Walter A. Jacobs and Michael Heidelberger. 21:103, 145, 403, 439, 455, 465 (1915). I. Structure of primary and secondary Walter A. Jacebs and Michael Heidelberger. 7. 80 Mercury derivativt6.0f4 aromatic amines. Proc. Nit. Acid. Sci., 1, 226 (1315) I. Contribution to the structure of 9-16. therefrom. salts. methylenetetraminium salts derived therefrom. tetraminium salts derived therefrom. tetraminium salts. hexmethylenetetrminium salts derived therefrom. J. Bfol. Chem., 20s 659, 685; 17. The bactericidal properties of the quaternary salts of hexamethylenetetramine. 11. lhe relation between constitution and bactericidal actio6 in the substituted btnzylhexamethylenetetronium salts. W. A. Jacobs, Michael Heidelberger and Harold L. hoss. J. Exp. Med., 23,569 (1916) 18, The bactericidal properties of the quaternary salts of hexamethylenetetruninar 111. The relation between constitution and bactericidal action in the quaternrky salts obtained from halogenacetyl compounds. and Carroll G. Bull. W..A. Jacobs, Midhilel Heidelberg& J. Exp. b.ed., 23:577 (1.936) -- Heidelb=er, Michael Bibliography e 2- 19. The ferrous sulfate and ammonia method for the reduction of nitro- to amin- compounds. W. A. Jacobs and Michael Heidelberger. J.Am.Chem. SOC., 39:1435 (1917) 20. Methods for the acetylation of aromatic amino compounds and ureas, with especial reference to chloroacetylation. Ibid. , 39 :1439 (1917) W. A. Jacobs and Michael Heidelberger. 21. Unsymmetrical derivatives of aromatic diamines. Heidelberger. Ibid., 39~1447, (1917) W. A. Jacobs and Michael 22. 23. 24. 25. On nitro and aminoaryl arsonic acids. W. A. Jacobs, Michael Heidelberger and The preparation of b-chloro and b-bromopropionic acids. On nitro and amino henoxyacetic acids. Ibid. 8 39r2188 (lgb) Amides, uramino compounds and ureides containing an aromatic nucleus. W. A. Jacobs and Michael Heidelberger. Ida P. Rolf. W. A. Jacobs and Michael Heidelberger. Ibid. , 3981465 (1917) W. A. Jacobs and Michael Heidelberger. Ibid., 39t2418 (1917) J. Am. Chem. SOC., 40~1580 (1918) 26-32. U. So Patents 1,280, 119-24; 1, 280,126. W.A.Jacobs, Wade H. Brown, Michael Heidelberger and Louise Pearce. 33. On certain aromatic amides and chloracetyl derivatives. W. A. Jacobs, Michael Heidelberger and Ida P. Rolf. Arsenical compounds. J. Am. Chem. Soc., 41:458 (1919) 34. 35. 36-43. Aromatic arsenic compoundsi On the isomeric hydroxyphenylarsonic acids and the direct orsenation of phenol. We Ab Jacobs and Michael Heidelberger. Certain amino and acylamino phenol ethers. Ibid. , 41 : 1450 (1919) I. A plan of procedure for the synthesis of arsenicals for chemotherapeutic re search. 11. The amides and alkyl amides of N-arylglycine arsonic acids. 111. The ureides and &substitute ureides of N-arylglycine arsonic acids, IV. Aromatic amides of N-hylglycihe arsonit acids. V. Ncsubstituted glycylarsanilic acids. VI. N=(Phenyl-4-arsonic acid)-x-phenylglycine and its amides. VII. Substituted benzyl, phenoxyethyl, and phenacylarsanilic acids. VIII.The amides of (4-arsonic acid)-phenoxyacetic acid and the isomeric phew oxyacetyl-arsanilic acids. We A. Jacobs and Michael Heidelberger. Ibid., 41:1581, 1587, 1600, 1610, 1809, 1822, 1826, 1834 (1919) its derivatives. Michael Heidelberger. 1. zhe simpler cinchona alkaloids and their dihydro- derivatives. 111. Azo-dyes derived from hydrocupreine and hydrocupreidine. V. Dihydrodesoxyquinine and dihydrodesoxyquinidine and their derivatives. IX. Certain quincine and benzoyl-cinchona salts, crystalline ethyldihydrcr cupreine (optochin) base, and other derivatives. Michael Heidelberger and W. A. Jacobs. 44~1091, 1098 (1922) Ibid., 41:1440 (1919) hiichael Heidelberger and W. A. Jacobs. 44, 45. Aromatic arsenic compounds. IX. Diazoarnino compounds of arsanilic acid and X. Azo dyes derived from arsanilic acid. Ibid., 43r1633, 1646 (1921) W. A. Jacobs and 46-49. S ntheses in the cinchona series. J. Am. Chem. SOC., 41,817, 2131 (1919); 42:1489 (1920); Heidclberqer, Michael Biblioqraphy - 3- 50-54. Syntheses in the cinchona series. 11. Quaternary salts. IV. Nitro and amino derivatives of the alkaloids. VI. Aminoazo and hydrozyazo dyes derived from certain 5-amino cinchona alkaloids and their quinoline analogs. VII. 5,8-diamino-dihydroquinine and 5,8-diamino-6-methoxyquinoline and their conversion into the corresponding aminohydroxy and dihydroxy bases. VIII. The hydrogenation of dihydrocinchonine, cinchonine, and dihydroquinine. W.A-Jacobs and Michael Heidelberger. (1920); 44: 1013, 1079 (1922). ibid. , 41r2090 (1919); 42: 1481, 2278 55. 56 . 57 . 58 o 60 . 61. 62. 63. 64. 65. 66 0 67. 68 . 69 o Certain triphenylmethane dyes. ibid. , 44: 2626 (1922). Strophanthin. I. Strophanthidin. W. A. Jacobs and Michael Heidelberger. J. Biol. Chem., 54: 253 (1922) A method for the preparation of crystalline oxyhemoglobin. J. Biol. Chem., 53:31 (1922) Studies of gas and electrolyte equilibria in the blood. and buffer values of oxyhemoglo~n and reduced hemoglobin. A. B. Hastings, Michael Heidelberger and J. M. Neill. 481 (1922) Book: An advanced laboratory manu41 of organic chemistry. Chemical Catalogue Co., New York 1923. W. A. Jacobs and Michael Heidelberger. Michael HeidelberTer 111. The alkali-binding 8, De D. VanSlyke, J. Biol. Chem., 54: Studies of gas and electrolyte equilibria in the blood. of reduced and oxygenated hemoglobin. A. B. Hastings, D. D. VanSlyke, J. M. Neill, Michael Heidelberger and C. R. Harington. IV. The acid properties ibid. j. 60s 89 (1924) Studies of gas and electrolyte equilibria in the blood, carbon monoxide on the acidity of hemoglobin. A. B. Hastings, J. Sendroy, Jr., C. D. Murray, and Michael Heidelberger. VII. The effect of ibid., 61: 317 (1924) On the antigenic properties of hemoglobin. Landsteiner. J. Exp. Med. , 38,. 561 (1923) Differentiation of oxyhemoglobins by means of mutual solubility tests. Karl Landsteiner and Michael Heidelberger. The soluble specific substance of pneumococcus. 0, T. Avery. J. Exp. Med., 38: 73 (1923) Immunological relationships of cell constituents of pneumococcus. 0. T. Avery and Michael Heidelberger. Michael Heidelberger and Karl J. Gen. Physiol., 6: 131 (1923) Michael Heidelberger and ibid., 38: 81 (1923) The soluble specific substance of pneumococcus. Michael Heidelberger and Oswald T. Avery. ibid., 40: 301 (1924) Immunological relationships of cell tonstituents of pneumococcus. 0. T. Avery and Michael Heidelberger. ibid., 42r367 (1925) Second paper. Second paper. The soluble specific substance of pneumococcus. Third paper. Michael Heidel- berger, The soluble specific substance of a strain of Friedlander's bacillus. Michael Heidelberger, W. F. Goebel, and 0. T. Avery. W. F. Goebel, and Oswald T. Avery. ibid., 42: 727 (1925) I. ibid., 42: 701 (1925) Heidelberger, Michael Bibliography -4- 70. 71. 72. 73 * 74. 75. 76. 77. 78. 79. The soluble specific substance of Friedlander's bacillus. logical relationships of pneumococcus Type I1 and a strain of Friedlander's bacillus. O.T. Avery, M. Heidelberger and W.F. Goebel. ibid., 42: 709 (1925) The soluble specific substance of pneumococcus. IV. On the nature of the specific polysaccharide of Type111 pneumococcus. M. Heidelberger and W.F. Geobel. J. Biol. Chem., 70: 613 (1926) The soluble specific substance of pneumococcus. V. On the chemical nature of the aldobionic acid from the specific polysaccharide of Type I11 pneumococcus. M. Heidelberger and W.F. Goebel. ibid., 74: 613 (1927) The chemical nature of immune substances. Physiol. Revs., 7: 107 (1927) Immunologically specific polysaccharides. Chem. Revs., 3: 403 (1927) Immunological relationships of the typhoid bacillus. G. Shwartzman, D.J. Cohn and M. Heidelberger. J. Biol. Chem., 78: 76 (1928) Behavior of the substance active in pernicious anemia on dialysis of liver extracts. J. Biol. Chem., 78, 76 (1928) N. Rosenthal, D.J. Cohn, J.S. Friedman, and M. Heidelberger Reaction between proteins and diazotized aromatic amines in neutral solution. M. Heidelberger and F.E. Kendall. Proc. SOC. Exp. Biol. and Med., 26: 482 (1929) Sarmentocymarin and Sarmentogenin. W.A. Jacobs and M. Heidelberger. J. Biol. Chem., 81: 705 (1929) A crystalline aldobionic acid derived from gum arabic. 11. Chemical and imuno- M. Heidelberger and F.E. 80. 81. 82. 83. 84. 85 saccharide and purified homologous antibody. M. Heidelberger and F.E. Kendall. J. Exp. Med., 50: 809-823 (1929) Le dgplacement de la toxine des mglanges neutralisges de toxine-antitoxine par la "toxoide" ou anatoxine. 104: 37 (May 3, 1930) The displacement of toxin from neutralized toxin-antitoxin mixtures by "toxoid" or anatoxin. M. Heidelberger and F.E. Kendall. Science, 71: 511 (May 16, 1930) Quantitative studies on the precipitin reaction. Science, 72: 252 (Sept. 5, 1930) F.E. Kendall and M. Heidelberger Quantitative studies on the precipitin reaction. tin following the injection of a soluble antigen. Science, 72: 253 (Sept. 5, 1930) Specific precipitation and mouse protection in Type I anti-pneumococcus sera. M. Heidelberger, &E:--Kendall&& R;H.P. SiapdJ. Exp. Med., 52: Specific and non-specific polysaccharides of Type IV pneumococcus. M. Heidelberger and F.E. Kendall. J. Exp. Med., 53: 625-639 (May 1931) .d Comptes Rendus des $Qances de la Soci6t6 de Biologie, Data on a protein-antibody system. The amount of circulating precipi- F.E. Kendall and M. Heidelberger. ---. _-- - 477 (Oct. 1930) .*. I 2 . -1- ~ -- I ' ... il\, -- .LC Heidelberger, Michael Bibliography -5- 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. 96. 97. 98. 99. 100. 101. 102. Protein fractions of a scarlatinal strain of streptococcus hemolyticus. Heidelberger and F.E. Kendall. J. Exp. Med., 54: 515-531 (Oct. 1931) Precipitin formation in S. viridans subacute endocarditis. D. Seegal, E. Jost, hi. Heidelberger. Proc. SOC. Exp. Biol. and Med., 29: 939-942 (1932) Immunochemistry. Ann. Rev. Biochem., 1: 655-673 (1932) Protein fractions of the timothy grass bacillus. A.E.O. Menzel and M. Heidelberger. Proc. SOC. Exp. Biol. and Med., 29: 512-513 (1932) Specific and non-specific cell polysaccharides of the human type of tubercle bacillus, H A.E.O. Menzel and M. Heidelberger. Proc. SOC. Exp. Biol. and Med., 29: 631-633 M. (G2) Some physico-chemical properties of specific polysaccharides. M. Heidelberger and F.E. Kendall. J. Biol. Chem., 95: 127-144 (Feb. 1932) Quantitative studies on the precipitin reaction. The determination of small amounts of a specific polysaccharide. M. Heidelberger and F.E. Kendall, J. Exp. Med., 55: 555-561 (apr. 1932) The molecular weight of specific polysaccharides. J. Biol. Chem., 96: 541-558 (May 1932) M. Heidelberger and F.E. Kendall, Streptococcus scarlatinae. D. Seegal and M. Heidelberger. J.A.M.A., 100: 186 (Jan. 21, 1933) Studies on the precipitin reaction. Precipitating haptens; species differences in antibodies. M. Heidelberger and F.E. Kendall. J. Exp. Med., 57: 373-379 (Mar. 1933) The preparation and properties of thyroglobulin. M. Heidelberger and W.W. Palmer, J. Biol. Chem., 101: 433-439 (July 1933) Quantitative studies on the precipitin reaction. Antibody production in rabbits injected with an azo protein. M. Heidelberger, F.E. Kendall and C.M. SOOHOO, J. Exp. Med., 58: 137-152 (Aug. 1933) Contributions of chemistry to the knowledge of immune processes. The Harvey Lectures, 1933, 28: 184-201; also in Medicine, 1933, 12: 279-295. M. Heidelberger. Immunochemistry. Ann. Rev. Biochem., vol. 2, 503-520, 1933. Precipitins against fractions of streptococci in hemolytic streptococcus disease, glomerular nephritis, rheumatoid arthritis and S. viridans endocarditis. D. Seegal, E.L. Jost, J.D. Lyttle and M. Heidelberger. Proc. SOC. Exp. Biol. and Med., 30: 582-585 (1933) Protein fractions of the human strain (H ) of tubercle bacillus. A.E.O. Meneel and M. Heidelberger. J. Biol. Chem., 10%; 655-665 (Mar. 1934) Quantitative studies on the precipitin reaction. The role of multiple reactive groups in antigen-antibody union as, jllustrated by an instance of cross-precipita- tion. M. Heidelberger and F.E. Kendall. J Exp. Med., 59: 519-528 (Apr. 1934) Heidelberqer, Michael Bibliography -6- 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. The formation of precipitin for the Group A specific carbohydrate of .%treptococcus hemolyticus in rabbits injected intravenously and subcutaneously. D. Seegal, E.L. Jost and M. Heidelberger. J. Immunology, 27: 211-214 (Aug. 1934) Chemical studies in bacterial agglutination. tive estimation of agglutinins. E.A. Kabat and M. Heidelberger. Proc. SOC. Exp. Biol. and Med., 31: 595-598 (1934) Chemical studies on bacterial agglutination. I. A method. M. Heidelberger and E.A. Kabat. J. Exp. Med., 60: 643-653 (Nov. 1934) The molecular weight of thyroglobulin. T. Svedberg and M. Heidelberger, Science, 80: 2079, 414 (Nov. 2, 1934) Immunochemistry. Textbook of biochemistry, Harrow, Sherwin. Saunders, Philadelphia 1935. Immunochemistry. Ann. Rev. Biochem., 4: 569-592 (1935) The precipitin reaction between Type I11 pneumococcus polysaccharide and homologous antibody. 11. Conditions for quantitative precipitation of antibody in horse sera. M. Heidelberger and F.E. Kendall. J. Exp. Med., 61: 559-562 (Apr. 1935) 111. A quantitative study and a theory of the reaction mechanism. ibid., 563-591 (1935) A quantitative theory of the precipitin reaction. I. A micro method for the quantita- 11. A study of an azo-protein- antibody system. M. Heidelberger and F.E. Kendall. J. Exp. (Oct. 1935) A quantitative theory of the precipitin reaction. 111. The line egg albumin and dhomologous antibody. M. Heidelberger Exp. Med., 62: 697-720 (Nov. 1935) Med., 62: 467-483 reaction between crystal- and F.E. Kendall. J. A complex polysaccharide fraction from the cells of the human type of tubercle bacil- lus, H A.E.O. Menzel and M. Heidelberger. Proc. SOC. Exp. Biol. and Med., 32: l?zi (1935) The molecular weight and isoelectric point of thyroglobulin. K.O. Pedersen. J. Gen. Physiol., 19: 95-108 (Sept. 20, 1935) Preparative changes necessitated by a quantitative study of precipitating power of pneumococcus polysaccharides. F.E. Kendall, H.W. Scherp and M. Heidelberger. Proc. SOC. Exp. Biol. & Med., 33: 188 (Oct. 1935) Carbohydrate-containing proteins of the hemolytic streptococcus. M. Heidelberger and F.E. Kendall. J. Immunol., 30: 267-273 (1936) Chemical studies on bacterial agglutination. agglutinin. M. Heidelberger and E.A. Kabat. J. Exp. Med., 63: 737-746 (May 1936) Quantitative studies on the'precipitin reaction. M. Heidelberger, F.E. Kendall and T. Teorell. J. Exp. Med., 63: 819-826 (June 1936) M. Heidelberger and 11. The identity of precipitin and Effect of salts on the reaction. Ultracentrifugal and electrophoretic studies on antibodies. K.O. Pedersen, A. Tiselius and M. Heidelberger. Nature, 138: 165 (July 1936) Heidelberqer, Michael Bibliography -7- 120. 121. 122. 123. 124. 125. 126. 127. 128. 129. 130. 131. 132. 133. 134. Quantitative studies on antibody purification. I. The dissociation of precipitates formed by pneumococcus specific polysaccharides and homologous antibodies. Heidelberger and F.E. Kendall. J. Exp. Med., 64:161-172 (Aug. 1936) The specific polysaccharides of Types I, 11, and I11 pneumococcus. A revision Of methods and data. M. Heidelberger, F.E. Kendall and H.W. Scherp. J. Exp. Med., M. 64:559-572 (Oct. 1936) The structure of natural and synthetic antigens. M. Heidelberger, Science, 84:2188:498 (Dec. 1936) A serologically inactive polysaccharide elaborated by mucoid strains of Group A hemolytic streptococcus. F.E. Kendall, M.H. Dawson and M. Heidelberger. J. Biol. Chem., 118 : 61-69 (March 1937) Specific and non-specific cell polysaccharides of a human strain of tubercle bacil- lus, H 1937) The molecular weight of antibodies. M. Heidelberger and K.O. Pedersen. J. Exp. Med., 65:393-414 (March 1937) A quantitative study of the cross reaction of Types I11 and VI11 pneumococci in horse and rabbit antisera. M. Heidelberger, E.A. Kabat, and D.L. Shrivastava. J. Exp. Med., 65:487-496 (Apr. 1937) A quantitative theory of the precipitin reaction. A.E.O. Menzel and M. Heidelberger. J. Biol. Chem., 118:79-100 (March 37 * IV. The reaction of pneumococcus specific Kendall. Chemic a 1 titative 1937) polysaccharides with homologous rabbit antisera. M. Heidelberger and F.E. J. Exp. Med., 65:647-660 (May 1937) studies on bacterial agglutination. 111. A reaction mechanism and a quan- theory. M. Heidelberger and E.A. Kabat. J. Exp. Med., 65:885-902 (June A quantitative theory of the precipitin reaction. line horse serum albumin and antibody formed in the rabbit. Heidelberger. J. Exp. Med., 66:229-250 (Aug. 1937) A quantitative theory of the precipitin reaction. The reaction between mam- malian thyroglobulins and antibodies to homologous and heterologous preparations. H.E. Stokinger and M. Heidelberger. J. Exp. Med., 66:251-272 (1937) Quantitative studies on antibody purification. 11. The dissociation of antibody from pneumococcus specific precipitates and specifically agglutinated pneumococci. M. Heidelberger and E.A. Kabat. J. Exp. Med., 67:181-199 (Feb. 1938) 9715-P. Preparation and administration of globulin from rabbit antipneumococcus sera. J.C. Turner, M. Heidelberger and C.M. SooHoo. Proc. SOC. Exp. Biol. & Med., V. The reaction between crystal- E.A. Kabat and M. VI. 37: 734-736 (1938) The molecular composition of specific Wune precipitates from rabbit sera. .M. Heidelberger, J. Am. Chem. S0c.t 60:242 (1938) Chemical studies on the tubercle bacillus and other acid-fast bacilli. "Tuberculosis and Leprosy", the mycobacterial diseases. Symposium series, Am. Assoc. for Adv. of Science, 1938, vol. 1. A.E.O. Menzel and M. Heidelberger. - Heidelberqer, Michael - Bibliography -8- 135; 136. 137. 139. 139. 1400 141. 142. 143. 144. 145. Chemical studies on bacterial agglutination. IV. Quantitative data on pneumococcus R (Dawson S)-anti-R (S) systems. J. Exp. bled., 67:545-550 (April 1938) Cell protein fractions of bovine and avian tubercle bacillus straihs and of the timothy grass bacillus. A.EDO.Menzel and M. Heidelberger. J. Biol. Chem., 124:301-7 (June 1938) E. A. Kabat and MD Heidelberger, Protein fractions of the human strain, H-37, of tubercle bacillus. A.E.G,Menzel and M. Heidelberger. J. Biol. Chem., 124:89-101 (June 1938) Les aspects chimiques de la fonction antige'ne et leurs rapports avec les agents infectieux. M. Heidelberger. Revue d'Immunologie, 4:293=303 (Juillet 1938) Reiation of proteins to immunity. Chapt. WII, The Chemistry of the Amino Acids, edited by C.L.A.Schmidtr C.C.Thomas, Springfield Ill., 1938. Quantitative studies on antibody purification. 111; The reaction of dissociated antibody with specific polysaccharide, and the-e3-fect of formaldehyde. Pierre Grabar and H. P. Treffers aRd f&-)leidelberg