R = Retrieve links to Related sequences (neighbors).
Use the 
icon (if present) to retrieve links to the Sequence Retrieval System (SRS).
Use the 
icon (if present) to retrieve links to the Ligand Enzyme and Chemical Compound Database .
Use the 
icon (if present) to retrieve links to the Protein Data Bank database.
WARNING: Descriptions of 760 database sequences were not reported due to the
limiting value of parameter V = 50.
>gi|5903104|gb|AAD55662.1|AC008017_35 (AC008017) Highly similar to non
intermediate filament IFA binding protein [Arabidopsis thaliana]
>gi|12324313|gb|AAG52122.1|AC010556_4 (AC010556) hypothetical
protein; 61711-63380 [Arabidopsis thaliana]
Length = 461
Frame 3 hits (HSPs): _____________________
__________________________________________________
Database sequence: | | | | | 461
0 150 300 450
Plus Strand HSPs:
Score = 342 (120.4 bits), Expect = 4.3e-30, P = 4.3e-30
Identities = 79/189 (41%), Positives = 111/189 (58%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDVV L LHDY +IIK+PMDLGTVK+ LSK++Y +P +FA DVRLTFNNA+ YNP GHD
Sbjct: 142 PVDVVTLGLHDYHNIIKEPMDLGTVKTRLSKSLYKSPLEFAEDVRLTFNNAMLYNPVGHD 201
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
VY MAE LL FEE + P+ ++E ++ ++ ++ + V+ P P
Sbjct: 202 VYHMAEILLNLFEEKWVPLETQYE-LLIRKQQPVRDIDFHAPVSTNTHNVEALPLPAPTP 260
Query: 372 KLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMSLEEKHK 551
L PPP+ N L ++ T +P++ P V P+ K + RD++ +EK +
Sbjct: 261 SLSPPPPPK---VVENRTLERAESMT-NPVK-PAVLPVVPEKLVEEASANRDLTFDEKRQ 315
Query: 552 LGLGLQSLP 578
L LQ LP
Sbjct: 316 LSEDLQDLP 324
>gi|11357202|pir||T49984 bromodomain protein-like - Arabidopsis thaliana
>gi|7671448|emb|CAB89388.1| (AL353995) bromodomain protein-like
[Arabidopsis thaliana]
Length = 678
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | | | 678
0 150 300 450 600
Plus Strand HSPs:
Score = 342 (120.4 bits), Expect = 2.8e-29, P = 2.8e-29
Identities = 82/178 (46%), Positives = 106/178 (59%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDVVGL LHDY I+ +PMDLGTVK NL K +Y +P DFASDVRLTF NA++YNPKG D
Sbjct: 272 PVDVVGLGLHDYHRIVDKPMDLGTVKMNLEKGLYRSPIDFASDVRLTFTNAMSYNPKGQD 331
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVH-----DRESEEELQASSWSQVE-PERVKKKE 353
VY MAE+LL++F+ + P ++FE V R E+ Q W+Q E +K
Sbjct: 332 VYLMAEKLLSQFDVWFNPTLKRFEAQEVKVMGSSSRPGPEDNQRV-WNQNNVAENARKGP 390
Query: 354 NPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMS 533
I AK P P PP+++ R PSP +P V+P P P + N+ + S
Sbjct: 391 EQISIAKKLDSVKPLLPTLPP-PPVIEI-TRDPSPPPSP-VQPPPPPSPPPQPVNQVEAS 447
Query: 534 LE 539
LE
Sbjct: 448 LE 449
Score = 150 (52.8 bits), Expect = 1.4e-08, P = 1.4e-08
Identities = 34/81 (41%), Positives = 45/81 (55%), Frame = +3
Query: 339 VKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPN 518
+ + +P PP+ + PPP P N VR + R K PKPKAKDPN
Sbjct: 417 ITRDPSP-PPSPVQPPPPPSPPPQPVNQVEASLEVRETNKGRKG-----KLPKPKAKDPN 470
Query: 519 KRDMSLEEKHKLGLGLQSLPP 581
KR+M+++EK KLG+ LQ LPP
Sbjct: 471 KREMTMDEKGKLGVNLQELPP 491
>gi|8978291|dbj|BAA98182.1| (AB026639) contains similarity to RING3
protein~gene_id:K21L13.15 [Arabidopsis thaliana]
Length = 643
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | | | 643
0 150 300 450 600
Plus Strand HSPs:
Score = 341 (120.0 bits), Expect = 3.0e-29, P = 3.0e-29
Identities = 83/174 (47%), Positives = 108/174 (62%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDVVGL LHDY ++K+PMDLGTVK NL K Y +P DFA+DVRLTF+NA+ YNPKG D
Sbjct: 247 PVDVVGLGLHDYHQVVKKPMDLGTVKLNLDKGFYVSPIDFATDVRLTFDNAMTYNPKGQD 306
Query: 192 VYTMAEQLLARFEELYRPVHEKFE-------GSIVH-DRESEEELQASSWSQVEP--ERV 341
VY MA++LL F+ ++ P +KFE GS + + + + + W+Q P
Sbjct: 307 VYFMADKLLDHFDGMFNPAFKKFEAQQLKLTGSSSRPEPDFKPDFKQRQWNQNPPMVANP 366
Query: 342 KKKENPIPPAK-LHKEPPPQHPASSSNPPLVQ-SPVRTPSPMRAPPV-KP-LKQPKP 500
+K I AK L PPQ P P LV+ S V++PSP PPV +P L QP+P
Sbjct: 367 RKGTEQISIAKKLDSVKPPQ-PTLP--PQLVEPSRVQSPSPPPPPPVIQPELPQPQP 420
Score = 337 (118.6 bits), Expect = 8.1e-29, P = 8.1e-29
Identities = 79/176 (44%), Positives = 99/176 (56%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDVVGL LHDY ++K+PMDLGTVK NL K Y +P DFA+DVRLTF+NA+ YNPKG D
Sbjct: 247 PVDVVGLGLHDYHQVVKKPMDLGTVKLNLDKGFYVSPIDFATDVRLTFDNAMTYNPKGQD 306
Query: 192 VYTMAEQLLARFEELYRPVHEKFE-------GSIVH-DRESEEELQASSWSQVEP--ERV 341
VY MA++LL F+ ++ P +KFE GS + + + + + W+Q P
Sbjct: 307 VYFMADKLLDHFDGMFNPAFKKFEAQQLKLTGSSSRPEPDFKPDFKQRQWNQNPPMVANP 366
Query: 342 KKKENPIPPAK-LHKEPPPQH--PASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKP 500
+K I AK L PPQ P P VQSP P P P P QP P
Sbjct: 367 RKGTEQISIAKKLDSVKPPQPTLPPQLVEPSRVQSPSPPPPPPVIQPELPQPQPPP 422
Score = 173 (60.9 bits), Expect = 4.3e-11, P = 4.3e-11
Identities = 41/86 (47%), Positives = 50/86 (58%), Frame = +3
Query: 324 VEPERVKKKENPIPPAKLHKE-PPPQHPASSSNPPLVQSPVRTPSPM-RAPPVKPLKQPK 497
VEP RV+ P PP + E P PQ P PP ++ V P + + K PK
Sbjct: 394 VEPSRVQSPSPPPPPPVIQPELPQPQPP-----PPQLEIEVEAPPDVSEVSKGRKGKLPK 448
Query: 498 PKAKDPNKRDMSLEEKHKLGLGLQSLPP 581
PKAKDPNKR M++EEK KLG+ LQ LPP
Sbjct: 449 PKAKDPNKRLMTMEEKSKLGMNLQDLPP 476
>gi|9665057|gb|AAF97259.1|AC034106_2 (AC034106) Contains similarity to female
sterile homeotic-related protein Frg-1 from Mus musculus
gb|AF045462 and contains a bromodomain PF|00439. [Arabidopsis
thaliana]
Length = 440
Frame 3 hits (HSPs): _______________________
__________________________________________________
Database sequence: | | | | 440
0 150 300
Plus Strand HSPs:
Score = 321 (113.0 bits), Expect = 7.2e-28, P = 7.2e-28
Identities = 80/192 (41%), Positives = 110/192 (57%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD GL LHDY +I+K+PMDLGTVK+ L K++Y +P DFA DVRLTFNNA+ YNP GHD
Sbjct: 155 PVDAKGLGLHDYHNIVKEPMDLGTVKTKLGKSLYKSPLDFAEDVRLTFNNAILYNPIGHD 214
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEE-ELQASSWSQVEPERVKKKENPIPP 368
VY AE LL FE+ + + +++ + + + E A + S + P + + I P
Sbjct: 215 VYRFAELLLNMFEDKWVSIEMQYDNLHRKFKPTRDIEFPAPAPS-IAP--IVEPLPAIVP 271
Query: 369 AKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAP--PVKPLKQPKPKAKD---P-NKRDM 530
+ PPP P + P L M P P + P+ KA++ P N RD+
Sbjct: 272 SPSPSSPPPPPPPPVAAPVLENRTWEREESMTIPVEPEAVITAPE-KAEEEEAPVNNRDL 330
Query: 531 SLEEKHKLGLGLQSLP 578
+LEEK +L LQ LP
Sbjct: 331 TLEEKRRLSEELQDLP 346
>gi|8844128|gb|AAF80220.1|AC025290_9 (AC025290) Contains similarity to a Ring3
protein from Homo sapiens gi|133157 and contains a bromodomain
PF|00439. EST gb|F14211 comes from this gene. [Arabidopsis
thaliana]
Length = 766
Frame 3 hits (HSPs): _____________
__________________________________________________
Database sequence: | | | | | | | 766
0 150 300 450 600 750
Plus Strand HSPs:
Score = 329 (115.8 bits), Expect = 9.8e-28, P = 9.8e-28
Identities = 83/191 (43%), Positives = 106/191 (55%), Frame = +3
Query: 9 APVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGH 188
APVDV GL L DY II+ PMDLGT+KS L KN+Y +P +FA DVRLTF+NA+ YNP+G
Sbjct: 443 APVDVKGLGLLDYYTIIEHPMDLGTIKSALMKNLYKSPREFAEDVRLTFHNAMTYNPEGQ 502
Query: 189 DVYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSW-SQVEPERVKKKENPIP 365
DV+ MA LL FEE + + + + E L + S++ P P P
Sbjct: 503 DVHLMAVTLLQIFEERWAVIEADYNREMRFVTGYEMNLPTPTMRSRLGPTM------PPP 556
Query: 366 PAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMSLEEK 545
P + A SN +P RTP+ P + KPKA +PNKRDM+ EEK
Sbjct: 557 PINVRNTIDR---ADWSNRQPTTTPGRTPTSA-TPSGRTPALKKPKANEPNKRDMTYEEK 612
Query: 546 HKLGLGLQSLPP 581
KL LQ+LPP
Sbjct: 613 QKLSGHLQNLPP 624
>gi|11358472|pir||T48600 kinase-like protein - Arabidopsis thaliana
>gi|7573452|emb|CAB87766.1| (AL163817) kinase-like protein
[Arabidopsis thaliana]
Length = 703
Frame 3 hits (HSPs): __________
__________________________________________________
Database sequence: | | | | | | 703
0 150 300 450 600
Plus Strand HSPs:
Score = 258 (90.8 bits), Expect = 3.6e-20, P = 3.6e-20
Identities = 54/128 (42%), Positives = 77/128 (60%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDVV L + DY ++I+ PMDLGTVK+ L+ Y+ P++FA+DVRLTF+NA+ YNP G+D
Sbjct: 160 PVDVVKLNILDYFNVIEHPMDLGTVKNKLTSGTYSCPSEFAADVRLTFSNAMTYNPPGND 219
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKK------- 350
VY MA+ L FE ++ + +K G+ VH S + + KK+
Sbjct: 220 VYVMADTLRKFFEVRWKTLEKKLSGTKVHTEPSNLDAHKEKHIVIPVPMAKKRKTTAVDC 279
Query: 351 ENPIPPAK 374
EN + PAK
Sbjct: 280 ENVVDPAK 287
>gi|10048444 ref|NP_065254.1| bromodomain-containing 4; bromodomain-containing
5 [Mus musculus] >gi|9931486|gb|AAG02191.1|AF273217_1 (AF273217)
cell proliferation related protein CAP [Mus musculus]
Length = 1400
Frame 3 hits (HSPs): _______ ____ ___________________________
__________________________________________________
Database sequence: | | | | 1400
0 500 1000
Plus Strand HSPs:
Score = 207 (72.9 bits), Expect = 4.0e-20, Sum P(2) = 4.0e-20
Identities = 41/88 (46%), Positives = 53/88 (60%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDV L LHDYCDIIK PMD+ T+KS L Y +F +DVRL F+N YNP H+
Sbjct: 380 PVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHE 439
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIV 275
V MA +L FE + + ++ E +V
Sbjct: 440 VVAMARKLQDVFEMRFAKMPDEPEEPVV 467
Score = 203 (71.5 bits), Expect = 7.8e-14, P = 7.8e-14
Identities = 60/181 (33%), Positives = 76/181 (41%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD V L L DY IIK PMD+GT+K L N Y + D F N YN G D
Sbjct: 86 PVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDD 145
Query: 192 VYTMAEQLLARF-EELYRPVHEKFEGSIVH----DRESEEELQASSWSQVEPERVKKKEN 356
+ MAE L F +++ E+ E IV R +E A P + +
Sbjct: 146 IVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGAAKPGVSTVPNTTQASTS 205
Query: 357 PIPPAKLHKEPPP----QHPASSSNPPLV-QSPVRT---PSPMRAPPVKPLKQPKPKAKD 512
P PPP HP + P L+ Q PV T P P++ P P + P P A
Sbjct: 206 PQTQTPQQNPPPPVQATTHPFPAVTPDLIAQPPVMTMVPPQPLQTPSPVPPQPPPPPAPV 265
Query: 513 P 515
P
Sbjct: 266 P 266
Score = 95 (33.4 bits), Expect = 1.7, P = 0.81
Identities = 33/123 (26%), Positives = 60/123 (48%), Frame = +3
Query: 210 QLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLH-KE 386
Q LA +E + VHE+ ++ ++++ + + + + E+ KKKE K KE
Sbjct: 510 QRLAELQEQLKAVHEQL-AALSQPQQNKPKKKEKDKKEKKKEKHKKKEEVEENKKSKTKE 568
Query: 387 PPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNK-RDMSLEEKHKLGLG 563
PP+ +++ S V P+ P K P ++++ +K + MS EEK +L L
Sbjct: 569 LPPKKTKKNNSS---NSNVSKKEPV---PTKTKPPPTYESEEEDKCKPMSYEEKRQLSLD 622
Query: 564 LQSLP 578
+ LP
Sbjct: 623 INKLP 627
Score = 84 (29.6 bits), Expect = 4.0e-20, Sum P(2) = 4.0e-20
Identities = 29/104 (27%), Positives = 45/104 (43%), Frame = +3
Query: 270 IVHDRESEEELQASSWSQVEPERVKKKENP---IPPAKLHKEPPPQHPASSSNPPLVQSP 440
++ D E S Q+ ++++K + P +P K+ +PPP P P VQ
Sbjct: 914 LLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH--PSVQQQ 971
Query: 441 VRTPSPMRAPPVKPLKQPKPKAK-DPNKRDMSLEEKHKLGLGLQSLPP 581
P P PP +P QP P+ + P R + L +Q PP
Sbjct: 972 QLQPQPPPPPPPQP--QPPPQQQHQPPPRPVHLPSM-PFSAHIQQPPP 1016
Score = 81 (28.5 bits), Expect = 8.1e-20, Sum P(2) = 8.1e-20
Identities = 29/92 (31%), Positives = 41/92 (44%), Frame = +3
Query: 294 EELQASSWSQVEPERVKKKE---NPI---PPAKLHKEP-PPQHPASSSNPP-LVQSPVRT 449
+EL+ S Q +P V K+E +PI P P PP+HP + P L Q P
Sbjct: 1130 QELRPPSVVQPQPLVVVKEEKIHSPIIRSEPFSTSLRPEPPKHPENIKAPVHLPQRPEMK 1189
Query: 450 PSPMRAPPVKPLKQPKPKAKDPNKRDMSLEEK 545
P + P ++P +Q P P+K E K
Sbjct: 1190 PVDIGRPVIRPPEQSAPPPGAPDKDKQKQEPK 1221
Score = 77 (27.1 bits), Expect = 2.1e-19, Sum P(2) = 2.1e-19
Identities = 32/106 (30%), Positives = 49/106 (46%), Frame = +3
Query: 294 EELQASSWSQVEPERVKKKE---NPI---PPAKLHKEP-PPQHPASSSNPP-LVQSPVRT 449
+EL+ S Q +P V K+E +PI P P PP+HP + P L Q P
Sbjct: 1130 QELRPPSVVQPQPLVVVKEEKIHSPIIRSEPFSTSLRPEPPKHPENIKAPVHLPQRPEMK 1189
Query: 450 PSPMRAPPVKPLKQ--PKPKA--KDPNKRDMSLEEKHKLGLGLQSL 575
P + P ++P +Q P P A KD K++ K L ++++
Sbjct: 1190 PVDIGRPVIRPPEQSAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNM 1235
Score = 73 (25.7 bits), Expect = 5.6e-19, Sum P(2) = 5.6e-19
Identities = 18/66 (27%), Positives = 34/66 (51%), Frame = +3
Query: 303 QASSWSQVEPER-VKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVK 479
Q+ V+P++ VK + P PP + + PAS + P++ +R PS ++ P+
Sbjct: 1085 QSPPQQNVQPKKQVKGRAEPQPPGPVMGQGQGCPPASPAAVPMLSQELRPPSVVQPQPLV 1144
Query: 480 PLKQPK 497
+K+ K
Sbjct: 1145 VVKEEK 1150
Score = 72 (25.3 bits), Expect = 7.1e-19, Sum P(2) = 7.1e-19
Identities = 28/88 (31%), Positives = 38/88 (43%), Frame = +3
Query: 261 EGSIVHDRESEEELQASSWSQVEPERVKKKEN----PI--P-PAKLHKEPPPQHPASSSN 419
E S +SE E+ S + R +KK + P P PA + ++PPP P
Sbjct: 709 ESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPVPQQPPPP-PQQPPP 767
Query: 420 PPLVQSPVRTPSPMRAPPVKPLKQPKPKAK 509
PP Q + P P PP P +Q P K
Sbjct: 768 PPPPQQQQQQPPPPPPPPSMP-QQTAPAMK 796
Score = 70 (24.6 bits), Expect = 1.1e-18, Sum P(2) = 1.1e-18
Identities = 26/92 (28%), Positives = 38/92 (41%), Frame = +3
Query: 255 KFEGSIVHDRESEEELQAS----SWSQVEPERVKKKENPIPPAKLHKEPPPQ-HPASSSN 419
K +G + ES E +S S +++ P+ KK K H PQ PA +
Sbjct: 695 KMKGFSSSESESTSESSSSDSEDSETEMAPKSKKKGHTGRDQKKHHHHHHPQMQPAPAPV 754
Query: 420 PPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPN 518
P P + P P PP + +QP P P+
Sbjct: 755 PQQPPPPPQQPPPP-PPPQQQQQQPPPPPPPPS 786
Score = 65 (22.9 bits), Expect = 3.8e-18, Sum P(2) = 3.8e-18
Identities = 20/63 (31%), Positives = 27/63 (42%), Frame = +3
Query: 363 PPAKLHKEPP-PQH----PASSS----NPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDP 515
PP + H+ PP P H P S+ PP Q P P + PP +P K + P
Sbjct: 988 PPQQQHQPPPRPVHLPSMPFSAHIQQPPPPPGQQPTHPPPGQQPPPPQPAKPQQVIQHHP 1047
Query: 516 NKR 524
+ R
Sbjct: 1048 SPR 1050
Score = 64 (22.5 bits), Expect = 4.8e-18, Sum P(2) = 4.8e-18
Identities = 23/64 (35%), Positives = 33/64 (51%), Frame = +3
Query: 324 VEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPS-PMRA----PPVKPLK 488
V+ ++++ + P PP + +PPPQ PP PV PS P A PP P +
Sbjct: 968 VQQQQLQPQPPPPPPPQ--PQPPPQQ---QHQPP--PRPVHLPSMPFSAHIQQPPPPPGQ 1020
Query: 489 QPK--PKAKDP 515
QP P + P
Sbjct: 1021 QPTHPPPGQQP 1031
Score = 64 (22.5 bits), Expect = 4.8e-18, Sum P(2) = 4.8e-18
Identities = 21/70 (30%), Positives = 28/70 (40%), Frame = +3
Query: 327 EPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKA 506
+P R + +PP PP PA + PPL+ P PM PP L+ +P A
Sbjct: 871 QPSRPSNRAAALPPKPTR--PPAVSPALAQ-PPLLPQP-----PMVQPPQVLLEDEEPPA 922
Query: 507 KDPNKRDMSL 536
M L
Sbjct: 923 PPLTSMQMQL 932
Score = 62 (21.8 bits), Expect = 7.8e-18, Sum P(2) = 7.8e-18
Identities = 24/80 (30%), Positives = 34/80 (42%), Frame = +3
Query: 357 PIPPAKLH-KEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQ-PKPK--AKDPNKR 524
P P H ++PPP ++PP Q P P P A P + ++ P P+ DP
Sbjct: 1003 PSMPFSAHIQQPPPPPGQQPTHPPPGQQP---PPPQPAKPQQVIQHHPSPRHHKSDPYSA 1059
Query: 525 DMSLEEKHKLGLGLQSLPPGLQSL 596
E L + +P QSL
Sbjct: 1060 GHLREAPSPLMIHSPQMPQ-FQSL 1082
Score = 61 (21.5 bits), Expect = 9.9e-18, Sum P(2) = 9.9e-18
Identities = 19/53 (35%), Positives = 24/53 (45%), Frame = +3
Query: 363 PPAKLHKEPPPQHPASSSNPPL-VQS--PVRTPSPMRAPPVKPLKQPKPKAKDP 515
P L E PP P +S L +Q V+ P+P+ P VK QP P P
Sbjct: 911 PQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPL-LPSVKVQSQPPPPLPPP 963
Score = 61 (21.5 bits), Expect = 9.9e-18, Sum P(2) = 9.9e-18
Identities = 22/70 (31%), Positives = 28/70 (40%), Frame = +3
Query: 321 QVEPERVKKKENPIPP-AKLHK--EPPPQHPASSSNP--PLVQSPVRTPSPMRAPPVKP- 482
++ P + E+ PP H PP H A P P ++ P P R P V P
Sbjct: 836 ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPTRPPAVSPA 895
Query: 483 LKQPKPKAKDP 515
L QP P P
Sbjct: 896 LAQP-PLLPQP 905
Score = 57 (20.1 bits), Expect = 2.6e-17, Sum P(2) = 2.6e-17
Identities = 15/59 (25%), Positives = 25/59 (42%), Frame = +3
Query: 321 QVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPK 497
Q P ++ P PP + ++PPP P S + +P P V P+ +P+
Sbjct: 756 QQPPPPPQQPPPPPPPQQQQQQPPPPPPPPSMPQQTAPAMKSSPPPFITAQV-PVLEPQ 813
Score = 47 (16.5 bits), Expect = 2.8e-16, Sum P(2) = 2.8e-16
Identities = 19/66 (28%), Positives = 30/66 (45%), Frame = +3
Query: 285 ESEEELQASSWSQVEPERVKKKENPIPPAKLHKEP---PPQHPA-SSSNPPLVQSPVRT- 449
ESEEE + S E ++ N +P KL + + P+ +SNP ++ T
Sbjct: 601 ESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETL 660
Query: 450 -PSPMR 464
PS +R
Sbjct: 661 KPSTLR 666
Score = 46 (16.2 bits), Expect = 3.6e-16, Sum P(2) = 3.6e-16
Identities = 20/66 (30%), Positives = 36/66 (54%), Frame = +3
Query: 327 EPERVKKKENPIPPAKLHKEPPPQ--HPASSSNPPLVQSPVRTPS----PMRAPP---VK 479
+P++V + +P P + HK P H + +P ++ SP + P ++PP V+
Sbjct: 1038 KPQQVIQ-HHPSP--RHHKSDPYSAGHLREAPSPLMIHSP-QMPQFQSLTHQSPPQQNVQ 1093
Query: 480 PLKQPKPKAK 509
P KQ K +A+
Sbjct: 1094 PKKQVKGRAE 1103
Score = 45 (15.8 bits), Expect = 4.6e-16, Sum P(2) = 4.6e-16
Identities = 11/38 (28%), Positives = 16/38 (42%), Frame = +3
Query: 348 KENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRT-PSP 458
++ P PP + PPP P Q ++ PSP
Sbjct: 1012 QQPPPPPGQQPTHPPPGQQPPPPQPAKPQQVIQHHPSP 1049
>gi|9294219|dbj|BAB02121.1| (AP000381) gb|AAF01563.1~gene_id:K17E12.8~similar
to unknown protein [Arabidopsis thaliana]
Length = 818
Frame 3 hits (HSPs): _________
__________________________________________________
Database sequence: | | | | | | | 818
0 150 300 450 600 750
Plus Strand HSPs:
Score = 258 (90.8 bits), Expect = 4.8e-20, P = 4.8e-20
Identities = 58/130 (44%), Positives = 77/130 (59%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+APVDVV L + DY IK PMDLGTVK NL+ VY++P +FA+DVRLTF NA+ YNP G
Sbjct: 197 QAPVDVVKLNIPDYLTTIKHPMDLGTVKKNLASGVYSSPHEFAADVRLTFTNAMTYNPPG 256
Query: 186 HDVYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIP 365
HDV+ M + L FE ++ + +K S + L A + +EP +K +P
Sbjct: 257 HDVHIMGDILSKLFEARWKTIKKKLPPC------SMQTLPAVT---LEPNDERKAAISVP 307
Query: 366 PAKLHKEPPP 395
PAK K P
Sbjct: 308 PAKKRKMASP 317
>gi|7523514|dbj|BAA94242.1| (AP001633) Similar to Arabidopsis thaliana
chromosome II BAC F19I3 genomic sequence; putative RING3 protein
(AC004238) [Oryza sativa]
Length = 507
Frame 3 hits (HSPs): _________________
__________________________________________________
Database sequence: | | | | | 507
0 150 300 450
Plus Strand HSPs:
Score = 249 (87.7 bits), Expect = 1.6e-19, P = 1.6e-19
Identities = 59/148 (39%), Positives = 82/148 (55%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY II +PMDLGTVKS L+ Y +P +FA DVRLTF NA+ YNPKG D
Sbjct: 165 PVDASALGLHDYHTIITKPMDLGTVKSRLAAGHYKSPREFAGDVRLTFQNAMRYNPKGQD 224
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
V+ MAEQLL FEE + P E + + +++ +V ++ + A
Sbjct: 225 VHFMAEQLLNMFEEKW-PEIEAEVAQLSPQPPTPSSAAPRKPKEIDNSKVLERSDSTVHA 283
Query: 372 KLHKEPPPQHPASSSNPPLVQSP-VRTPS 455
+ P Q+ + PP+++ P R P+
Sbjct: 284 AGMEATPKQN---TGRPPVLKKPKAREPN 309
Score = 114 (40.1 bits), Expect = 0.0028, P = 0.0028
Identities = 31/91 (34%), Positives = 47/91 (51%), Frame = +3
Query: 315 WSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRT--PSPMRAPPVKPLK 488
W ++E E + +P PP P+ P N +++ T + M A P +
Sbjct: 240 WPEIEAEVAQL--SPQPPTP--SSAAPRKPKEIDNSKVLERSDSTVHAAGMEATPKQNTG 295
Query: 489 QP----KPKAKDPNKRDMSLEEKHKLGLGLQSLPP 581
+P KPKA++PNKR+M+ EK +L LQ LPP
Sbjct: 296 RPPVLKKPKAREPNKREMTFWEKQRLSNNLQELPP 330
>gi|10177441|dbj|BAB10737.1| (AB023035) contains similarity to
kinase~gene_id:K9H21.3 [Arabidopsis thaliana]
Length = 477
Frame 3 hits (HSPs): _______________
__________________________________________________
Database sequence: | | | | | 477
0 150 300 450
Plus Strand HSPs:
Score = 243 (85.5 bits), Expect = 5.9e-19, P = 5.9e-19
Identities = 55/128 (42%), Positives = 79/128 (61%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L + DY ++IK PMDLGT++S L K Y++P DFA+DVRLTF+N++AYNP G
Sbjct: 182 RTPVDPVMLNIPDYFNVIKHPMDLGTIRSRLCKGEYSSPLDFAADVRLTFSNSIAYNPPG 241
Query: 186 HDVYTMAEQLLARFEELYRPVHEKFEGSI--VHDRESEEELQASSWSQVEPERVKKKENP 359
+ +TMA+ + FE ++ + +K S V S L++ +V P R KKE
Sbjct: 242 NQFHTMAQGISKYFESGWKSIEKKIPMSKPPVIPLTSSASLESEIPFEVAPMR--KKEAA 299
Query: 360 IPPAKLHKEP 389
+ KL EP
Sbjct: 300 MNDNKLRVEP 309
>gi|8885596|dbj|BAA97526.1| (AB028605) contains similarity to
kinase~gene_id:F10E10.2 [Arabidopsis thaliana]
Length = 506
Frame 3 hits (HSPs): __________ _____
__________________________________________________
Database sequence: | | | | | 506
0 150 300 450
Plus Strand HSPs:
Score = 210 (73.9 bits), Expect = 4.5e-18, Sum P(2) = 4.5e-18
Identities = 41/84 (48%), Positives = 62/84 (73%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
K PVD V +++ DY ++I++PMDLGTVKS L KNVY+ +FA+DVRLTF NA+ YNP
Sbjct: 102 KEPVDPVKMEIPDYFNVIQKPMDLGTVKSKLLKNVYSNADEFAADVRLTFANAMHYNPLW 161
Query: 186 HDVYTMAEQLLARFEELYRPVHEK 257
++V+T+A+++ FE + + +K
Sbjct: 162 NEVHTIAKEINEIFEVRWESLMKK 185
Score = 48 (16.9 bits), Expect = 4.5e-18, Sum P(2) = 4.5e-18
Identities = 14/50 (28%), Positives = 23/50 (46%), Frame = +3
Query: 414 SNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMSLEEKHKLGLG 563
SN L+ + ++T P PPV P K + ++ KH++ LG
Sbjct: 326 SNSDLLGNELKTAFPA-LPPVPPEKALRAAILKAQYAGTIIKAKHRIVLG 374
>gi|6016737|gb|AAF01563.1|AC009325_33 (AC009325) hypothetical protein
[Arabidopsis thaliana] >gi|6091741|gb|AAF03453.1|AC010797_29
(AC010797) hypothetical protein [Arabidopsis thaliana]
Length = 601
Frame 3 hits (HSPs): ___________
__________________________________________________
Database sequence: | | | | || 601
0 150 300 450 600
Plus Strand HSPs:
Score = 231 (81.3 bits), Expect = 2.1e-17, P = 2.1e-17
Identities = 49/117 (41%), Positives = 71/117 (60%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDVV L + DY IIK PMDLGTVKS L+ Y++P++F++DVRLTF NA+ YNP ++
Sbjct: 152 PVDVVKLNIPDYFTIIKHPMDLGTVKSKLTSGTYSSPSEFSADVRLTFRNAMTYNPSDNN 211
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPI 362
VY A+ L FE ++ + +K G+ + + L + EP K+K N +
Sbjct: 212 VYRFADTLSKFFEVRWKTIEKKSSGT-KSEPSNLATLAHKDIAIPEPVAKKRKMNAV 267
>gi|1588281|prf||2208296A RING3 protein [Homo sapiens]
Length = 509
Frame 3 hits (HSPs): _______ ____________________
__________________________________________________
Database sequence: | | | | | 509
0 150 300 450
Plus Strand HSPs:
Score = 215 (75.7 bits), Expect = 8.0e-16, P = 8.0e-16
Identities = 67/192 (34%), Positives = 94/192 (48%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 210 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 269
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQV-EPERVKKKENPIPP 368
V MA +L FE Y + ++ E R E+L A S + +P+R ++K+
Sbjct: 270 VVAMARKLQDVFEFRYAKMPDEPEQL----RAVHEQLAALSQGPISKPKRKREKKEKKKK 325
Query: 369 AKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPK---------AKDPNK 521
K K PP P + +S + R + K P K A++P+
Sbjct: 326 RKA-KTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSL 384
Query: 522 RDMSLEEKHKLGLGLQSLPP 581
RD + EE + + ++L P
Sbjct: 385 RDSNPEE---IEIDFETLKP 401
Score = 143 (50.3 bits), Expect = 2.0e-07, P = 2.0e-07
Identities = 30/70 (42%), Positives = 37/70 (52%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 53 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 112
Query: 186 HDVYTMAEQL 215
D+ MA+ L
Sbjct: 113 DDIVLMAQTL 122
>gi|157455|gb|AAA28541.1| (M23222) 5.9 kb fsh membrane protein [Drosophila
melanogaster]
Length = 1110
Frame 3 hits (HSPs): ____ _____ _______
Frame 2 hits (HSPs): __ ___
__________________________________________________
Database sequence: | | | | | | | | | 1110
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 198 (69.7 bits), Expect = 8.7e-16, Sum P(2) = 8.7e-16
Identities = 41/89 (46%), Positives = 51/89 (57%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK+PMDLGTVK + Y + +FA+DVRL F N YNP HD
Sbjct: 506 PVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHD 565
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVH 278
V M +L FE Y + ++ + H
Sbjct: 566 VVAMGRKLQDVFEMRYANIPDEPVANAAH 594
Score = 156 (54.9 bits), Expect = 7.6e-13, Sum P(3) = 7.6e-13
Identities = 32/68 (47%), Positives = 37/68 (54%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L L DY IIKQPMD+GT+K L N Y + + D FNN YN G D
Sbjct: 62 PVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGED 121
Query: 192 VYTMAEQL 215
V MA+ L
Sbjct: 122 VVVMAQTL 129
Score = 49 (17.2 bits), Expect = 8.7e-16, Sum P(2) = 8.7e-16
Identities = 33/121 (27%), Positives = 50/121 (41%), Frame = +3
Query: 255 KFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEP---PPQHPA-SSSNP 422
K + S V + +SEEE A S E ++ N +P KL + + P+ SNP
Sbjct: 932 KKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNP 991
Query: 423 PLVQSPVRT--PSPMR-----APPVKPLKQPKPKAKDPN---KRDMSLEEKHKLGLGLQS 572
++ T PS +R K KP K P+ K + E+K +L LQ
Sbjct: 992 DEIEIDFETLKPSTLRELESYVASCLRKKTRKPYYKKPSGKSKDEQMAEKKQELEKRLQD 1051
Query: 573 L 575
+
Sbjct: 1052 V 1052
Score = 43 (15.1 bits), Expect = 3.7e-15, Sum P(2) = 3.7e-15
Identities = 8/24 (33%), Positives = 14/24 (58%), Frame = +3
Query: 507 KDPNKRDMSLEEKHKLGLGLQSLP 578
++ + MS +EK +L L + LP
Sbjct: 945 EEDTAKPMSYDEKRQLSLDINKLP 968
Score = 41 (14.4 bits), Expect = 5.9e-15, Sum P(2) = 5.9e-15
Identities = 12/53 (22%), Positives = 27/53 (50%), Frame = +2
Query: 344 EKGESDPSCKIA*RTSTAAPCKFFKSSIGAVSGAHTIPNASSSCEAFEATKAE 502
EK D + ++ TA + S + AV A+ + ++SSS ++ ++ ++
Sbjct: 1046 EKRLQDVTGQLGASKKTAKKDESASSKVEAVQPANPVSSSSSSSDSSSSSSSD 1098
Score = 41 (14.4 bits), Expect = 7.6e-13, Sum P(3) = 7.6e-13
Identities = 12/36 (33%), Positives = 19/36 (52%), Frame = +2
Query: 389 STAAPCKFFKSSIGAVSGAHTIP----NASSSCEAF 484
+ AA + GA GA TIP NA+++ +A+
Sbjct: 338 AAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAY 373
>gi|7485801|pir||T00472 hypothetical protein F19I3.13 - Arabidopsis thaliana
>gi|3033386|gb|AAC12830.1| (AC004238) RING3-like bromodomain
protein [Arabidopsis thaliana]
Length = 400
Frame 3 hits (HSPs): _____________
__________________________________________________
Database sequence: | | | | 400
0 150 300
Plus Strand HSPs:
Score = 211 (74.3 bits), Expect = 1.1e-15, P = 1.1e-15
Identities = 44/97 (45%), Positives = 60/97 (61%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDV GL LHDY +I++PMDLGT+K + + Y+ + +DVRL F NA+ YN + D
Sbjct: 133 PVDVKGLGLHDYYKVIEKPMDLGTIKKKMESSEYSNVREIYADVRLVFKNAMRYNEEKED 192
Query: 192 VYTMAEQLLARFEELYRPVHEKF--EGSIVHDRESEE 296
VY MAE LL +FEE + + K E D E+E+
Sbjct: 193 VYVMAESLLEKFEEKWLLIMPKLVEEEKKQVDEEAEK 229
>gi|7657218 ref|NP_055114.1| bromodomain-containing protein 4; similar to
RING3; chromosome-associated protein [Homo sapiens] >gi|11426510
ref|XP_009302.1| bromodomain-containing protein 4 [Homo sapiens]
>gi|12229690|sp|O60885|BRD4_HUMAN BROMODOMAIN-CONTAINING PROTEIN 4
(HUNK1 PROTEIN) >gi|3115204|emb|CAA72780.1| (Y12059) strong
homology to human RING3 sequence [Homo sapiens]
Length = 722
Frame 3 hits (HSPs): ______________ __________________
__________________________________________________
Database sequence: | | | | | | 722
0 150 300 450 600
Plus Strand HSPs:
Score = 215 (75.7 bits), Expect = 1.6e-15, P = 1.6e-15
Identities = 57/180 (31%), Positives = 85/180 (47%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDV L LHDYCDIIK PMD+ T+KS L Y +F +DVRL F+N YNP H+
Sbjct: 379 PVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHE 438
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
V MA +L FE + + ++ E +V S + + P + +
Sbjct: 439 VVAMARKLQDVFEMRFAKMPDEPEEPVV--AVSSPAVPPPTKVVAPPSSSDSSSDSSSDS 496
Query: 372 KLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMSLEEKHK 551
+ + A +Q ++ A +P +Q KPK K+ +K++ +EKHK
Sbjct: 497 DSSTDDSEEERAQRLAE--LQEQLKAVHEQLAALSQP-QQNKPKKKEKDKKEKK-KEKHK 552
Score = 205 (72.2 bits), Expect = 1.9e-14, P = 1.9e-14
Identities = 62/176 (35%), Positives = 76/176 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD V L L DY IIK PMD+GT+K L N Y + D F N YN G D
Sbjct: 86 PVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDD 145
Query: 192 VYTMAEQLLARF-EELYRPVHEKFEGSIVH----DRESEEELQASSWSQVEPERVKKKEN 356
+ MAE L F +++ E+ E IV R +E A P +
Sbjct: 146 IVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTP 205
Query: 357 PIPPAKLHKEPPPQ---HPASSSNPPL-VQSPVRT---PSPMRAPP-VKPLKQPKP 500
P PP Q HP + P L VQ+PV T P P++ PP V P QP P
Sbjct: 206 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPP 261
Score = 109 (38.4 bits), Expect = 0.018, P = 0.018
Identities = 36/123 (29%), Positives = 67/123 (54%), Frame = +3
Query: 210 QLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLH-KE 386
Q LA +E + VHE+ ++ ++++ + + + + E+ K+KE K KE
Sbjct: 509 QRLAELQEQLKAVHEQL-AALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE 567
Query: 387 PPPQHPA--SSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNK-RDMSLEEKHKLG 557
PPP+ +SSN + + + P+PM++ P P P ++++ +K + MS EEK +L
Sbjct: 568 PPPKKTKKNNSSNSNVSK---KEPAPMKSKP--P---PTYESEEEDKCKPMSYEEKRQLS 619
Query: 558 LGLQSLP 578
L + LP
Sbjct: 620 LDINKLP 626
>gi|3184498|gb|AAC27978.1| (AC004798) R31546_1 [Homo sapiens]
Length = 731
Frame 3 hits (HSPs): _____________ __________________
__________________________________________________
Database sequence: | | | | | | 731
0 150 300 450 600
Plus Strand HSPs:
Score = 215 (75.7 bits), Expect = 1.6e-15, P = 1.6e-15
Identities = 57/180 (31%), Positives = 85/180 (47%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDV L LHDYCDIIK PMD+ T+KS L Y +F +DVRL F+N YNP H+
Sbjct: 390 PVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHE 449
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
V MA +L FE + + ++ E +V S + + P + +
Sbjct: 450 VVAMARKLQDVFEMRFAKMPDEPEEPVV--AVSSPAVPPPTKVVAPPSSSDSSSDSSSDS 507
Query: 372 KLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMSLEEKHK 551
+ + A +Q ++ A +P +Q KPK K+ +K++ +EKHK
Sbjct: 508 DSSTDDSEEERAQRLAE--LQEQLKAVHEQLAALSQP-QQNKPKKKEKDKKEKK-KEKHK 563
Score = 205 (72.2 bits), Expect = 1.9e-14, P = 1.9e-14
Identities = 62/176 (35%), Positives = 76/176 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD V L L DY IIK PMD+GT+K L N Y + D F N YN G D
Sbjct: 97 PVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDD 156
Query: 192 VYTMAEQLLARF-EELYRPVHEKFEGSIVH----DRESEEELQASSWSQVEPERVKKKEN 356
+ MAE L F +++ E+ E IV R +E A P +
Sbjct: 157 IVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTP 216
Query: 357 PIPPAKLHKEPPPQ---HPASSSNPPL-VQSPVRT---PSPMRAPP-VKPLKQPKP 500
P PP Q HP + P L VQ+PV T P P++ PP V P QP P
Sbjct: 217 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPP 272
Score = 109 (38.4 bits), Expect = 0.018, P = 0.018
Identities = 36/123 (29%), Positives = 67/123 (54%), Frame = +3
Query: 210 QLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLH-KE 386
Q LA +E + VHE+ ++ ++++ + + + + E+ K+KE K KE
Sbjct: 520 QRLAELQEQLKAVHEQL-AALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE 578
Query: 387 PPPQHPA--SSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNK-RDMSLEEKHKLG 557
PPP+ +SSN + + + P+PM++ P P P ++++ +K + MS EEK +L
Sbjct: 579 PPPKKTKKNNSSNSNVSK---KEPAPMKSKP--P---PTYESEEEDKCKPMSYEEKRQLS 630
Query: 558 LGLQSLP 578
L + LP
Sbjct: 631 LDINKLP 637
>gi|120558|sp|P13709|FSH_DROME FEMALE STERILE HOMEOTIC PROTEIN (FRAGILE-CHORION
MEMBRANE PROTEIN) >gi|280611|pir||A43742 female sterile homeotic
protein, 205K - fruit fly (Drosophila melanogaster)
>gi|157453|gb|AAA28540.1| (M23221) 7.6 kb fsh membrane protein
[Drosophila melanogaster]
Length = 2038
Frame 3 hits (HSPs): ___ ___ ____ __
Frame 2 hits (HSPs): __ __
Annotated Domains: ___________________________________________ ___
__________________________________________________
Database sequence: | | | | || 2038
0 500 1000 1500 2000
__________________
Annotated Domains:
DOMO DM00265: BROMODOMAIN 27..141
DOMO DM07091: BROMODOMAIN 303..466
DOMO DM00265: BROMODOMAIN 468..585
DOMO DM07090: BROMODOMAIN 587..1105
Entrez Domain: BROMODOMAIN. 51..123
Entrez Domain: BROMODOMAIN. 495..567
Entrez Domain: ET DOMAIN. 945..1106
Entrez Transmembrane region: POTENTIAL. 330..350
Entrez Transmembrane region: POTENTIAL. 451..471
Entrez Transmembrane region: POTENTIAL. 750..770
Entrez Transmembrane region: POTENTIAL. 790..810
Entrez Transmembrane region: POTENTIAL. 816..830
Entrez Transmembrane region: POTENTIAL. 874..894
Entrez Transmembrane region: POTENTIAL. 1731..1751
Entrez Transmembrane region: POTENTIAL. 1939..1959
PFAM bromodomain: Bromodomain 39..128
PFAM bromodomain: Bromodomain 483..572
PRINTS BROMODOMAIN1: Bromodomain motif I - 4 54..67
PRINTS BROMODOMAIN2: Bromodomain motif II - 4 70..86
PRINTS BROMODOMAIN3: Bromodomain motif III - 4 86..104
PRINTS BROMODOMAIN4: Bromodomain motif IV - 4 548..567
PRODOM PD082551: FSH_DROME 1..31
PRODOM PD000747: Q18210(5) Q90941(5) T2D1(4) 33..140
PRODOM PD085699: FSH_DROME 142..275
PRODOM PD000540: H1(18) O76786(11) TONB(10) 279..368
PRODOM PD082566: FSH_DROME 373..454
PRODOM PD000747: Q18210(5) Q90941(5) T2D1(4) 472..590
PRODOM PD046748: FSH_DROME 643..673
PRODOM PD052974: FSH_DROME 730..789
PRODOM PD000540: H1(18) O76786(11) TONB(10) 805..931
PRODOM PD007379: 941..1037
PRODOM PD084835: FSH_DROME 1039..1077
PRODOM PD124311: FSH_DROME 1104..1376
PRODOM PD001830: HSP1(29) VE2(21) GAG(12) 1378..1421
PRODOM PD055030: FSH_DROME 1423..1496
PRODOM PD000002: MYSP(25) MYSA(19) INVO(17) 1498..1713
PRODOM PD056265: FSH_DROME 1952..2037
__________________
Plus Strand HSPs:
Score = 198 (69.7 bits), Expect = 1.8e-15, Sum P(2) = 1.8e-15
Identities = 41/89 (46%), Positives = 51/89 (57%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK+PMDLGTVK + Y + +FA+DVRL F N YNP HD
Sbjct: 506 PVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHD 565
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVH 278
V M +L FE Y + ++ + H
Sbjct: 566 VVAMGRKLQDVFEMRYANIPDEPVANAAH 594
Score = 156 (54.9 bits), Expect = 5.9e-12, Sum P(3) = 5.9e-12
Identities = 32/68 (47%), Positives = 37/68 (54%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L L DY IIKQPMD+GT+K L N Y + + D FNN YN G D
Sbjct: 62 PVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGED 121
Query: 192 VYTMAEQL 215
V MA+ L
Sbjct: 122 VVVMAQTL 129
Score = 52 (18.3 bits), Expect = 1.8e-15, Sum P(2) = 1.8e-15
Identities = 32/117 (27%), Positives = 51/117 (43%), Frame = +3
Query: 255 KFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEP---PPQHPA-SSSNP 422
K + S V + +SEEE A S E ++ N +P KL + + P+ SNP
Sbjct: 932 KKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNP 991
Query: 423 PLVQSPVRT--PSPMR------APPVKPLKQPKPKAKDPNKRDMSLEEKHKLGLGLQSL 575
++ T PS +R A ++ KP K +K + E+K +L LQ +
Sbjct: 992 DEIEIDFETLKPSTLRELESYVASCLRKKTHKKPSGK--SKDEQMAEKKQELEKRLQDV 1048
Score = 43 (15.1 bits), Expect = 1.6e-14, Sum P(2) = 1.6e-14
Identities = 8/24 (33%), Positives = 14/24 (58%), Frame = +3
Query: 507 KDPNKRDMSLEEKHKLGLGLQSLP 578
++ + MS +EK +L L + LP
Sbjct: 945 EEDTAKPMSYDEKRQLSLDINKLP 968
Score = 41 (14.4 bits), Expect = 2.5e-14, Sum P(2) = 2.5e-14
Identities = 12/53 (22%), Positives = 27/53 (50%), Frame = +2
Query: 344 EKGESDPSCKIA*RTSTAAPCKFFKSSIGAVSGAHTIPNASSSCEAFEATKAE 502
EK D + ++ TA + S + AV A+ + ++SSS ++ ++ ++
Sbjct: 1042 EKRLQDVTGQLGASKKTAKKDESASSKVEAVQPANPVSSSSSSSDSSSSSSSD 1094
Score = 41 (14.4 bits), Expect = 5.9e-12, Sum P(3) = 5.9e-12
Identities = 12/36 (33%), Positives = 19/36 (52%), Frame = +2
Query: 389 STAAPCKFFKSSIGAVSGAHTIP----NASSSCEAF 484
+ AA + GA GA TIP NA+++ +A+
Sbjct: 338 AAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAY 373
Score = 39 (13.7 bits), Expect = 4.1e-14, Sum P(2) = 4.1e-14
Identities = 12/49 (24%), Positives = 24/49 (48%), Frame = +3
Query: 408 SSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNK-RDMSLEEKHK 551
+S+N P + + S P + +Q + KAK+ ++ + + EK K
Sbjct: 1649 ASANSPQSHTSSSSSSSKAKPAMDSFQQFRNKAKERDRLKLLEAAEKEK 1697
>gi|10728524|gb|AAF46312.2| (AE003442) fs(1)h gene product [Drosophila
melanogaster]
Length = 1937
Frame 3 hits (HSPs): ___ ___ ____ ___
Frame 2 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | 1937
0 500 1000 1500
Plus Strand HSPs:
Score = 198 (69.7 bits), Expect = 3.3e-15, Sum P(2) = 3.3e-15
Identities = 41/89 (46%), Positives = 51/89 (57%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK+PMDLGTVK + Y + +FA+DVRL F N YNP HD
Sbjct: 506 PVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHD 565
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVH 278
V M +L FE Y + ++ + H
Sbjct: 566 VVAMGRKLQDVFEMRYANIPDEPVANAAH 594
Score = 156 (54.9 bits), Expect = 5.0e-12, Sum P(3) = 5.0e-12
Identities = 32/68 (47%), Positives = 37/68 (54%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L L DY IIKQPMD+GT+K L N Y + + D FNN YN G D
Sbjct: 62 PVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGED 121
Query: 192 VYTMAEQL 215
V MA+ L
Sbjct: 122 VVVMAQTL 129
Score = 49 (17.2 bits), Expect = 3.3e-15, Sum P(2) = 3.3e-15
Identities = 33/121 (27%), Positives = 50/121 (41%), Frame = +3
Query: 255 KFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEP---PPQHPA-SSSNP 422
K + S V + +SEEE A S E ++ N +P KL + + P+ SNP
Sbjct: 932 KKKPSQVMNFDSEEEDTAKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNP 991
Query: 423 PLVQSPVRT--PSPMR-----APPVKPLKQPKPKAKDPN---KRDMSLEEKHKLGLGLQS 572
++ T PS +R K KP K P+ K + E+K +L LQ
Sbjct: 992 DEIEIDFETLKPSTLRELESYVASCLRKKTRKPYYKKPSGKSKDEQMAEKKQELEKRLQD 1051
Query: 573 L 575
+
Sbjct: 1052 V 1052
Score = 43 (15.1 bits), Expect = 1.4e-14, Sum P(2) = 1.4e-14
Identities = 8/24 (33%), Positives = 14/24 (58%), Frame = +3
Query: 507 KDPNKRDMSLEEKHKLGLGLQSLP 578
++ + MS +EK +L L + LP
Sbjct: 945 EEDTAKPMSYDEKRQLSLDINKLP 968
Score = 41 (14.4 bits), Expect = 5.0e-12, Sum P(3) = 5.0e-12
Identities = 12/36 (33%), Positives = 19/36 (52%), Frame = +2
Query: 389 STAAPCKFFKSSIGAVSGAHTIP----NASSSCEAF 484
+ AA + GA GA TIP NA+++ +A+
Sbjct: 338 AAAAAAAAAGGAAGAAGGAGTIPAVAVNAANAVQAY 373
Score = 39 (13.7 bits), Expect = 3.6e-14, Sum P(2) = 3.6e-14
Identities = 12/49 (24%), Positives = 24/49 (48%), Frame = +3
Query: 408 SSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNK-RDMSLEEKHK 551
+S+N P + + S P + +Q + KAK+ ++ + + EK K
Sbjct: 1548 ASANSPQSHTSSSSSSSKAKPAMDSFQQFRNKAKERDRLKLLEAAEKEK 1596
>gi|11067749 ref|NP_031397.1| bromodomain-containing protein 3; RING3-like
gene; open reading frame X [Homo sapiens] >gi|12735201
ref|XP_011836.1| bromodomain-containing protein 3 [Homo sapiens]
>gi|12643726|sp|Q15059|BRD3_HUMAN BROMODOMAIN-CONTAINING PROTEIN 3
(RING3-LIKE PROTEIN) >gi|452519|dbj|BAA05393.1| (D26362) similar to
Human homolog of Drosophila female sterile homeotic mRNA ( HUMFSHG)
[Homo sapiens]
Length = 726
Frame 3 hits (HSPs): _____________ ______________ ___
__________________________________________________
Database sequence: | | | | | | 726
0 150 300 450 600
Plus Strand HSPs:
Score = 210 (73.9 bits), Expect = 5.5e-15, P = 5.5e-15
Identities = 69/194 (35%), Positives = 92/194 (47%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L+LHDY DIIK PMDL TVK + Y FA+DVRL F+N YNP H+
Sbjct: 337 PVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHE 396
Query: 192 VYTMAEQLLARFEELYRPV-HEKFEGSIV-------------HDRESEEELQASSWSQVE 329
V MA +L FE + + E E + R SEE S S E
Sbjct: 397 VVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSE 456
Query: 330 PERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAK 509
ER + A+L ++ H ++ L Q+PV P + K K+ K K K
Sbjct: 457 EERATRL------AELQEQLKAVHEQLAA---LSQAPVNKPKKKKEKKEKE-KKKKDKEK 506
Query: 510 DPNKRDMSLEEKHKLGLGLQSLPPGLQS 593
+ K + EE+ K + PP Q+
Sbjct: 507 EKEKHKVKAEEEKKAKVA----PPAKQA 530
Score = 163 (57.4 bits), Expect = 1.9e-11, Sum P(2) = 1.9e-11
Identities = 46/165 (27%), Positives = 74/165 (44%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L L DY IIK PMD+GT+K L N Y + ++ D F N YN D
Sbjct: 62 PVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDD 121
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
+ MA+ L F + + ++ E ++ + + ++ +Q + + + PA
Sbjct: 122 IVLMAQALEKIFLQKVAQMPQE-EVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA 180
Query: 372 KLHKEPPPQHPASSSNPPLVQSPVRT-PSPMRAPPVKPLKQPKPKA 506
+ PP S P + +PV T + + + PV P P P A
Sbjct: 181 TPFQSVPP---TVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPA 223
Score = 155 (54.6 bits), Expect = 1.3e-10, Sum P(2) = 1.3e-10
Identities = 49/173 (28%), Positives = 76/173 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L L DY IIK PMD+GT+K L N Y + ++ D F N YN D
Sbjct: 62 PVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDD 121
Query: 192 VYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPP 368
+ MA+ L F +++ + E+ E + + + A+ ++V + P
Sbjct: 122 IVLMAQALEKIFLQKVAQMPQEEVE-LLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA 180
Query: 369 AKLHKEPPP--QHPASSSNP-PLVQSPVRT-P-SPMRAPP-----VKPLKQPKP 500
PP Q P ++ P P + + V + P P APP + P+ P P
Sbjct: 181 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTP 234
Score = 38 (13.4 bits), Expect = 1.9e-11, Sum P(2) = 1.9e-11
Identities = 11/39 (28%), Positives = 18/39 (46%), Frame = +3
Query: 477 KPLKQPKPKAKDPNKRDMSLEEKHKLGLGLQSLPPGLQS 593
KP K +K +++ E+K +L LQ + L S
Sbjct: 643 KPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSS 681
>gi|2995269|emb|CAA15818.1| (AL009226) MMRING3.1.1 [Mus musculus]
Length = 752
Frame 3 hits (HSPs): _______________ ______________
__________________________________________________
Database sequence: | | | | | || 752
0 150 300 450 600 750
Plus Strand HSPs:
Score = 210 (73.9 bits), Expect = 5.8e-15, P = 5.8e-15
Identities = 65/194 (33%), Positives = 86/194 (44%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 328 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 387
Query: 192 VYTMAEQLLARFEELYRPV-HEKFE------------GSIVHDRESEEELQASSWSQVEP 332
V MA +L FE Y + E E G ES E +S S E
Sbjct: 388 VVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLTKSSSESSSEESSSESSSEEE 447
Query: 333 ERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTP-SPMRAPPVKPLKQPKPKAK 509
E ++ E+ E H + +Q +R + A P+ +PK K +
Sbjct: 448 EEEEEDEDEEESESSDSEEERAHRLAE-----LQEQLRAVHEQLAALSQGPISKPKRKRE 502
Query: 510 DPNKRDMSLEEKHKLGLGL 566
K+ EKH+ +G+
Sbjct: 503 KKEKKKKRKAEKHRGRIGI 521
Score = 170 (59.8 bits), Expect = 1.1e-10, P = 1.1e-10
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 53 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 112
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 113 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVS 172
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 173 S-VSHTALYT-PPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKK 230
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 231 GVKRKADTTTPTPTAILAPGSPASPPG 257
>gi|2995270|emb|CAA15819.1| (AL009226) MMRING3.1.2 [Mus musculus]
>gi|3041763|dbj|BAA25416.1| (D89801) Ring3 [Mus musculus]
>gi|3811391|gb|AAC69907.1| (AF100956) RING3 [Mus musculus]
Length = 798
Frame 3 hits (HSPs): _____________ _____________
__________________________________________________
Database sequence: | | | | | | | 798
0 150 300 450 600 750
Plus Strand HSPs:
Score = 210 (73.9 bits), Expect = 6.4e-15, P = 6.4e-15
Identities = 65/194 (33%), Positives = 86/194 (44%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 374 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 433
Query: 192 VYTMAEQLLARFEELYRPV-HEKFE------------GSIVHDRESEEELQASSWSQVEP 332
V MA +L FE Y + E E G ES E +S S E
Sbjct: 434 VVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLTKSSSESSSEESSSESSSEEE 493
Query: 333 ERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTP-SPMRAPPVKPLKQPKPKAK 509
E ++ E+ E H + +Q +R + A P+ +PK K +
Sbjct: 494 EEEEEDEDEEESESSDSEEERAHRLAE-----LQEQLRAVHEQLAALSQGPISKPKRKRE 548
Query: 510 DPNKRDMSLEEKHKLGLGL 566
K+ EKH+ +G+
Sbjct: 549 KKEKKKKRKAEKHRGRIGI 567
Score = 170 (59.8 bits), Expect = 1.2e-10, P = 1.2e-10
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 99 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 158
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 159 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVS 218
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 219 S-VSHTALYT-PPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKK 276
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 277 GVKRKADTTTPTPTAILAPGSPASPPG 303
>gi|6753910 ref|NP_034368.1| female sterile homeotic-related gene 1 [Mus
musculus] >gi|3273701|gb|AAC24810.1| (AF045462) female sterile
homeotic-related protein Frg-1 [Mus musculus]
Length = 798
Frame 3 hits (HSPs): _____________ _____________
__________________________________________________
Database sequence: | | | | | | | 798
0 150 300 450 600 750
Plus Strand HSPs:
Score = 210 (73.9 bits), Expect = 6.4e-15, P = 6.4e-15
Identities = 65/194 (33%), Positives = 86/194 (44%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 374 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 433
Query: 192 VYTMAEQLLARFEELYRPV-HEKFE------------GSIVHDRESEEELQASSWSQVEP 332
V MA +L FE Y + E E G ES E +S S E
Sbjct: 434 VVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLTKSSSESSSEESSSESSSEEE 493
Query: 333 ERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTP-SPMRAPPVKPLKQPKPKAK 509
E ++ E+ E H + +Q +R + A P+ +PK K +
Sbjct: 494 EEEEEDEDEEESESSDSEEERAHRLAE-----LQEQLRAVHEQLAALSQGPISKPKRKRE 548
Query: 510 DPNKRDMSLEEKHKLGLGL 566
K+ EKH+ +G+
Sbjct: 549 KKEKKKKRKAEKHRGRIGI 567
Score = 170 (59.8 bits), Expect = 1.2e-10, P = 1.2e-10
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 99 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 158
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 159 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGGKLAALQGSITSAHQVPAVS 218
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 219 S-VSHTALYT-PPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKK 276
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 277 GVKRKADTTTPTPTAILAPGSPASPPG 303
>gi|8575733|gb|AAF78072.1| (AF269193) bromodomain-containing FSH-like protein
FSRG2 [Mus musculus]
Length = 726
Frame 3 hits (HSPs): ____________ _____________
__________________________________________________
Database sequence: | | | | | | 726
0 150 300 450 600
Plus Strand HSPs:
Score = 208 (73.2 bits), Expect = 9.0e-15, P = 9.0e-15
Identities = 69/180 (38%), Positives = 88/180 (48%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L+LHDY DIIK PMDL TVK + Y FA+D+RL F+N YNP H+
Sbjct: 336 PVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHE 395
Query: 192 VYTMAEQLLARFEELYRPV-HEKFEGS--------IVH-----DRESEEELQASSWSQVE 329
V MA +L FE + + E E IV R SEE S S E
Sbjct: 396 VVAMARKLQDVFEMRFAKMPDEPMEAPALPAPTAPIVSKGAESSRSSEESSSDSGSSDSE 455
Query: 330 PERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAK 509
ER + A+L ++ H + L Q+PV P + K K+ K K K
Sbjct: 456 EERATRL------AELQEQLKAVHEQLDA---LSQAPVNKPKKKKE---KKEKEKKKKDK 503
Query: 510 DPNKRDMSLEEKHK 551
D +K +EKHK
Sbjct: 504 DKDKE----KEKHK 513
Score = 160 (56.3 bits), Expect = 1.3e-09, P = 1.3e-09
Identities = 46/165 (27%), Positives = 74/165 (44%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L L DY IIK PMD+GT+K L N Y + ++ D F N YN D
Sbjct: 61 PVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDD 120
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
+ MA+ L F + + ++ E ++ + + ++ +Q + + + PA
Sbjct: 121 IVLMAQALEKIFLQKVAQMPQE-EVELLPPAPKGKGRKPAAGAQNAGSQQVAAVSSVSPA 179
Query: 372 KLHKEPPPQHPASSSNPPLVQSPVRT-PSPMRAPPVKPLKQPKPKA 506
+ PP S P + +PV T + + + PV P P P A
Sbjct: 180 TPFQNIPP---TVSQTPVIAATPVPTITANVTSVPVPPPAAPPPPA 222
Score = 159 (56.0 bits), Expect = 1.6e-09, P = 1.6e-09
Identities = 49/173 (28%), Positives = 76/173 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L L DY IIK PMD+GT+K L N Y + ++ D F N YN D
Sbjct: 61 PVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDD 120
Query: 192 VYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPP 368
+ MA+ L F +++ + E+ E + + + A+ ++V + P
Sbjct: 121 IVLMAQALEKIFLQKVAQMPQEEVE-LLPPAPKGKGRKPAAGAQNAGSQQVAAVSSVSPA 179
Query: 369 AKLHKEPPP--QHPASSSNP-PLVQS-----PVRTPS--PMRAPPVKPLKQPKP 500
PP Q P ++ P P + + PV P+ P A P+ P+ P P
Sbjct: 180 TPFQNIPPTVSQTPVIAATPVPTITANVTSVPVPPPAAPPPPATPIVPVVPPTP 233
Score = 150 (52.8 bits), Expect = 1.5e-08, P = 1.5e-08
Identities = 45/168 (26%), Positives = 73/168 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L L DY IIK PMD+GT+K L N Y + ++ D F N YN D
Sbjct: 61 PVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDD 120
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
+ MA+ L F + + ++ E ++ + + ++ +Q + + + PA
Sbjct: 121 IVLMAQALEKIFLQKVAQMPQE-EVELLPPAPKGKGRKPAAGAQNAGSQQVAAVSSVSPA 179
Query: 372 KLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDP 515
+ PP + S P++ + TP P V + P P A P
Sbjct: 180 TPFQNIPP----TVSQTPVIAA---TPVPTITANVTSVPVPPPAAPPP 220
>gi|10441758|gb|AAG17179.1|AF191032_1 (AF191032) RING3 [Myxine glutinosa]
Length = 732
Frame 3 hits (HSPs): _______________ ___________________
__________________________________________________
Database sequence: | | | | | | 732
0 150 300 450 600
Plus Strand HSPs:
Score = 173 (60.9 bits), Expect = 1.4e-14, Sum P(2) = 1.4e-14
Identities = 36/81 (44%), Positives = 46/81 (56%), Frame = +3
Query: 15 VDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHDV 194
VD L LHDY DIIK PMDL T+K + Y +FA D+RL F+N YNP H+V
Sbjct: 436 VDAFALGLHDYHDIIKIPMDLTTIKEKFERREYTNLHEFADDMRLMFSNCYKYNPPDHEV 495
Query: 195 YTMAEQLLARFEELYRPVHEK 257
MA +L FE + V ++
Sbjct: 496 VAMARKLQDVFEMRFAKVPDE 516
Score = 145 (51.0 bits), Expect = 5.2e-08, P = 5.2e-08
Identities = 56/194 (28%), Positives = 78/194 (40%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L L DY IIK P+D+ T+K L N Y T + D F N YN D
Sbjct: 58 PVDAAKLNLPDYYQIIKNPLDMLTIKKRLESNYYWTAVECIQDFSTMFTNCYIYNRPNDD 117
Query: 192 VYTMAEQLLARFEELYR--PVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIP 365
+ MA+ + F + PV E S V + ++ + +P V P+
Sbjct: 118 IVLMAQTVEKAFLQKVAEMPVEEYEITSPVARVPQRRGRKPAALTAAQPV-VTAGPVPLS 176
Query: 366 PAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAP--PVKPLKQPKPKAKDPNKRDMSLE 539
P H P P+ S PP + T A P PL+ + N+ S+
Sbjct: 177 P---HI---PAAPSPSQRPPRAAAAAATQQIAAAQTLPASPLRLEQQCGPVQNQMARSVS 230
Query: 540 EKHKLG---LGLQSLPPGLQS 593
+G L S PG+QS
Sbjct: 231 TPPAVGQPTLETPSAAPGVQS 251
Score = 58 (20.4 bits), Expect = 1.4e-14, Sum P(2) = 1.4e-14
Identities = 29/124 (23%), Positives = 54/124 (43%), Frame = +3
Query: 216 LARFEELYRPVHEKF----EGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHK 383
LA +E + +HE+ + I ++ +E + +E R + E + KL
Sbjct: 570 LAELQEQLKALHEQLASLSQAPISKPKKKKERKEKRKDKVLEKARKWEDEEKVLKNKL-L 628
Query: 384 EPPPQHPASSSNPPLVQSPVRTP---SPMRAPPVKPLKQPKPKAKDPNKRDMSLEEKHKL 554
+ +S+N P+ + + + S + A P P P +D R M+ +EK +L
Sbjct: 629 QAKKMGKQNSNNRPIKKEELDSTIGASSLNAIPNVPTTLPDG-TEDA--RPMTYDEKRQL 685
Query: 555 GLGLQSLP 578
L + LP
Sbjct: 686 SLDINRLP 693
Score = 47 (16.5 bits), Expect = 2.0e-13, Sum P(2) = 2.0e-13
Identities = 10/21 (47%), Positives = 10/21 (47%), Frame = +3
Query: 420 PPLVQSPVRTPSPMRAPPVKP 482
PP VQ PV P PP P
Sbjct: 519 PPPVQPPVTPQLPTTPPPPPP 539
Score = 45 (15.8 bits), Expect = 3.2e-13, Sum P(2) = 3.2e-13
Identities = 12/38 (31%), Positives = 14/38 (36%), Frame = +3
Query: 438 PVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMSLEEKHK 551
P TP P PPV P P P+ S E +
Sbjct: 514 PDETPPPPVQPPVTPQLPTTPPPPPPDVHLTSSESSRE 551
Score = 40 (14.1 bits), Expect = 1.1e-12, Sum P(2) = 1.1e-12
Identities = 11/25 (44%), Positives = 13/25 (52%), Frame = +3
Query: 351 ENPIPPAKLHKEPP--PQHPASSSNPP 425
E P PP +PP PQ P + PP
Sbjct: 516 ETPPPPV----QPPVTPQLPTTPPPPP 538
>gi|11358238|pir||T46098 hypothetical protein T25B15.50 - Arabidopsis thaliana
>gi|10045561|emb|CAC07919.1| (AL132972) putative protein
[Arabidopsis thaliana]
Length = 369
Frame 3 hits (HSPs): _______________ ____ ____
__________________________________________________
Database sequence: | | | | 369
0 150 300
Plus Strand HSPs:
Score = 173 (60.9 bits), Expect = 1.5e-14, Sum P(2) = 1.5e-14
Identities = 43/101 (42%), Positives = 63/101 (62%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNL-SKNV--YATPADFASDVRLTFNNALAYNPK 182
PV+V GL LHDY ++I +PMD T+K+ + +K+ Y +D+RL F NA+ YN +
Sbjct: 117 PVNVEGLGLHDYFEVIDKPMDFSTIKNQMEAKDGTGYKHVMQIYADMRLVFENAMNYNEE 176
Query: 183 GHDVYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQAS 311
DVY+MA++LL +FEE + K + RE EEE QA+
Sbjct: 177 TSDVYSMAKKLLEKFEEKWAHFLPKVQEE-EKIRE-EEEKQAA 217
Score = 47 (16.5 bits), Expect = 1.5e-14, Sum P(2) = 1.5e-14
Identities = 9/20 (45%), Positives = 13/20 (65%), Frame = +3
Query: 522 RDMSLEEKHKLGLGLQSLPP 581
R +++EEK +GL L L P
Sbjct: 258 RKITIEEKRNIGLALLKLSP 277
Score = 39 (13.7 bits), Expect = 1.0e-13, Sum P(2) = 1.0e-13
Identities = 8/25 (32%), Positives = 13/25 (52%), Frame = +3
Query: 282 RESEEELQASSWSQVEPERVKKKEN 356
++ EEE + S + + V KK N
Sbjct: 330 KKKEEETKTRELSGAQKKEVSKKRN 354
>gi|7493489|pir||T40984 transcription factor bdf1 homolog - fission yeast
(Schizosaccharomyces pombe) >gi|4581512|emb|CAB40169.1| (AL049559)
putative transcription factor ; yeast bdf1-like
[Schizosaccharomyces pombe]
Length = 578
Frame 3 hits (HSPs): _________ ___________
__________________________________________________
Database sequence: | | | | | 578
0 150 300 450
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 1.6e-14, P = 1.6e-14
Identities = 48/121 (39%), Positives = 67/121 (55%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD V DY D+IK+PMDL T++S L+KN Y+T +F SD+ L FNN YNP G
Sbjct: 282 PVDPVACDCPDYFDVIKEPMDLSTIQSKLNKNEYSTLEEFESDILLMFNNCFTYNPPGTP 341
Query: 192 VYTMAEQLLARFEELYRPVHEKFE-GSIVHDRESEEELQASSWSQVEPERVKKKENPIPP 368
V+ M QL F+E + KF+ ++V +E+E + + + E E E I
Sbjct: 342 VHVMGRQLENVFKEKWE-ARPKFDDATLVKQQEAETD---ALFDNGEEEEALMSEEEING 397
Query: 369 AK 374
AK
Sbjct: 398 AK 399
Score = 144 (50.7 bits), Expect = 9.4e-08, P = 9.4e-08
Identities = 30/98 (30%), Positives = 52/98 (53%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
K PVD + + DY I+K PMDLGT++ L+ Y+ P +F D+ L F+N YN
Sbjct: 110 KVPVDPIKQNIPDYPTIVKNPMDLGTIEKKLTSYEYSVPQEFIDDMNLMFSNCFLYNGTE 169
Query: 186 HDVYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEE 299
V +M + L FE + + + + + ++S+++
Sbjct: 170 SPVGSMGKALQEVFERQLKQLPDAEQPAAAPVKKSKQK 207
>gi|7291557|gb|AAF46981.1| (AE003460) CG17692 gene product [Drosophila
melanogaster]
Length = 268
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | | | | 268
0 50 100 150 200 250
Plus Strand HSPs:
Score = 194 (68.3 bits), Expect = 2.1e-14, P = 2.1e-14
Identities = 52/146 (35%), Positives = 69/146 (47%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
P+D L LHDY +I+++PMDL TV+ L+ Y + ADFA D+RL F N Y H
Sbjct: 39 PLDPQLLGLHDYHEIVREPMDLSTVRHRLNTGCYLSAADFAKDIRLIFYNTYLYTNPDHL 98
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPA 371
Y MA+QL FEE+Y V S R EE S S + V E + P+
Sbjct: 99 CYHMAKQLQIIFEEMYSQVQLYICSSGSKVRAEEESSSDESDSSSPEDEVNGSE--VSPS 156
Query: 372 KLHKEPPPQHPASSSNPPLVQSPVRT 449
+ PP P + P +P T
Sbjct: 157 -IMGAPPSCTPTTECTPTPDWTPPAT 181
>gi|1082363|pir||A56619 female sterile homeotic (fsh) homolog RING3 - human
>gi|182769|gb|AAA68890.1| (M80613) putative [Homo sapiens]
Length = 754
Frame 3 hits (HSPs): ______________ ______________
Annotated Domains: _____ _____
__________________________________________________
Database sequence: | | | | | || 754
0 150 300 450 600 750
__________________
Annotated Domains:
Entrez domain: bromodomain homology #label BRO1 52..109
Entrez domain: bromodomain homology #label BRO2 325..382
PROSITE BROMODOMAIN_1: Bromodomain signature. 322..381
PROSITE BROMODOMAIN_1: Bromodomain signature. 49..108
__________________
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 2.6e-14, P = 2.6e-14
Identities = 63/190 (33%), Positives = 82/190 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 328 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 387
Query: 192 VYTMAEQLLARFEELYR------------PVHEKFEGSIVHD--RESEEELQASSWSQVE 329
V MA +L FE Y PV + S EE + S S+ E
Sbjct: 388 VVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEE 447
Query: 330 PERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTP-SPMRAPPVKPLKQPKPKA 506
E ++ E E H + +Q +R + A P+ +PK K
Sbjct: 448 EEEDEEDEEEEESESSDSEEERAHRLAE-----LQEQLRAVHEQLAALSQGPISKPKRKR 502
Query: 507 KDPNKRDMSLEEKHK 551
+ K+ EKH+
Sbjct: 503 EKKEKKKKRKAEKHR 517
Score = 171 (60.2 bits), Expect = 8.9e-11, P = 8.9e-11
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 53 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 112
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 113 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVS 172
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 173 S-VSHTALYT-PPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKK 230
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 231 GVKRKADTTTPTPTAILAPGSPASPPG 257
>gi|1370115|emb|CAA65450.1| (X96670) kinase [Homo sapiens]
>gi|2181873|emb|CAB06495.1| (Z84497) RING3 [Homo sapiens]
>gi|2181875|emb|CAB09533.1| (Z96104) RING3 [Homo sapiens]
Length = 754
Frame 3 hits (HSPs): ______________ ______________
__________________________________________________
Database sequence: | | | | | || 754
0 150 300 450 600 750
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 2.6e-14, P = 2.6e-14
Identities = 63/190 (33%), Positives = 82/190 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 328 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 387
Query: 192 VYTMAEQLLARFEELYR------------PVHEKFEGSIVHD--RESEEELQASSWSQVE 329
V MA +L FE Y PV + S EE + S S+ E
Sbjct: 388 VVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEE 447
Query: 330 PERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTP-SPMRAPPVKPLKQPKPKA 506
E ++ E E H + +Q +R + A P+ +PK K
Sbjct: 448 EEEDEEDEEEEESESSDSEEERAHRLAE-----LQEQLRAVHEQLAALSQGPISKPKRKR 502
Query: 507 KDPNKRDMSLEEKHK 551
+ K+ EKH+
Sbjct: 503 EKKEKKKKRKAEKHR 517
Score = 171 (60.2 bits), Expect = 8.9e-11, P = 8.9e-11
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 53 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 112
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 113 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVS 172
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 173 S-VSHTALYT-PPPEIPTTVFNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKK 230
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 231 GVKRKADTTTPTPTAILAPGSPASPPG 257
>gi|4826806 ref|NP_005095.1| bromodomain-containing protein 2; female sterile
homeotic-related gene 1 [Homo sapiens]
>gi|12230989|sp|P25440|BRD2_HUMAN BROMODOMAIN-CONTAINING PROTEIN 2
(RING3 PROTEIN) >gi|577293|dbj|BAA07641.1| (D42040) female sterile
homeotic (fsh) homolog RING3 [Homo sapiens]
>gi|2980663|emb|CAA43996.1| (X62083) FSH [Homo sapiens]
Length = 801
Frame 3 hits (HSPs): _____________ _____________
__________________________________________________
Database sequence: | | | | | | | 801
0 150 300 450 600 750
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 2.8e-14, P = 2.8e-14
Identities = 63/190 (33%), Positives = 82/190 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 375 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 434
Query: 192 VYTMAEQLLARFEELYR------------PVHEKFEGSIVHD--RESEEELQASSWSQVE 329
V MA +L FE Y PV + S EE + S S+ E
Sbjct: 435 VVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEE 494
Query: 330 PERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTP-SPMRAPPVKPLKQPKPKA 506
E ++ E E H + +Q +R + A P+ +PK K
Sbjct: 495 EEEDEEDEEEEESESSDSEEERAHRLAE-----LQEQLRAVHEQLAALSQGPISKPKRKR 549
Query: 507 KDPNKRDMSLEEKHK 551
+ K+ EKH+
Sbjct: 550 EKKEKKKKRKAEKHR 564
Score = 171 (60.2 bits), Expect = 9.7e-11, P = 9.7e-11
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 100 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 159
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 160 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVS 219
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 220 S-VSHTALYT-PPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKK 277
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 278 GVKRKADTTTPTPTAILAPGSPASPPG 304
>gi|11417904 ref|XP_004219.1| bromodomain-containing protein 2 [Homo sapiens]
Length = 801
Frame 3 hits (HSPs): _____________ _____________
__________________________________________________
Database sequence: | | | | | | | 801
0 150 300 450 600 750
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 2.8e-14, P = 2.8e-14
Identities = 63/190 (33%), Positives = 82/190 (43%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 375 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 434
Query: 192 VYTMAEQLLARFEELYR------------PVHEKFEGSIVHD--RESEEELQASSWSQVE 329
V MA +L FE Y PV + S EE + S S+ E
Sbjct: 435 VVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEE 494
Query: 330 PERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTP-SPMRAPPVKPLKQPKPKA 506
E ++ E E H + +Q +R + A P+ +PK K
Sbjct: 495 EEEDEEDEEEEESESSDSEEERAHRLAE-----LQEQLRAVHEQLAALSQGPISKPKRKR 549
Query: 507 KDPNKRDMSLEEKHK 551
+ K+ EKH+
Sbjct: 550 EKKEKKKKRKAEKHR 564
Score = 171 (60.2 bits), Expect = 9.7e-11, P = 9.7e-11
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 100 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 159
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 160 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVS 219
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 220 S-VSHTALYT-PPPEIPTTVFNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKK 277
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 278 GVKRKADTTTPTPTAILAPGSPASPPG 304
>gi|12722620 ref|XP_001996.2| testis-specific bromodomain protein [Homo
sapiens]
Length = 582
Frame 3 hits (HSPs): _________________
__________________________________________________
Database sequence: | | | | | 582
0 150 300 450
Plus Strand HSPs:
Score = 198 (69.7 bits), Expect = 7.3e-14, P = 7.3e-14
Identities = 67/188 (35%), Positives = 88/188 (46%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDV L LH+Y D++K PMDLGT+K + Y FA+DVRL F N YNP H+
Sbjct: 193 PVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHE 252
Query: 192 VYTMAEQLLARFEELY-----RPVHE------KFEGSIVHDRESEEEL--QASSWSQVEP 332
V TMA L FE + PV K + + RE+ E + +S E
Sbjct: 253 VVTMARMLQDVFETHFSKIPIEPVESIPLCYIKTDITETTGRENTNEASSEGNSSDDSED 312
Query: 333 ERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKD 512
ERVK+ AKL ++ H L Q P R + + K K+ K +
Sbjct: 313 ERVKRL------AKLQEQLKAVHQQLQV---LSQVPFRKLNKKKEKSKKEKKKEKVNNSN 363
Query: 513 PNKR----DMSLEEKHK 551
N R M L+EK K
Sbjct: 364 ENPRKMCEQMRLKEKSK 380
>gi|1345703|sp|P45481|CBP_MOUSE CREB-BINDING PROTEIN >gi|481698|pir||S39161
CREB-binding protein - mouse >gi|435855|gb|AAB28651.1| (S66385)
CREB-binding protein, CBP [mice, brain, Peptide, 2441 aa] [Mus sp.]
Length = 2441
Frame 3 hits (HSPs): ___ ____ __
Frame 1 hits (HSPs): __
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | | 2441
0 500 1000 1500 2000
__________________
Annotated Domains:
DOMO DM03835: BROMODOMAIN 225..417
DOMO DM03494: BROMODOMAIN 419..478
DOMO DM04744: BROMODOMAIN 480..1076
DOMO DM00265: BROMODOMAIN 1078..1194
DOMO DM04743: BROMODOMAIN 1196..2251
Entrez Domain: BROMODOMAIN. 1104..1176
Entrez Domain: POLY-GLU. 1062..1065
Entrez Domain: POLY-GLU. 1556..1563
Entrez Domain: POLY-PRO. 1944..1949
Entrez Domain: POLY-GLN. 1968..1971
Entrez Domain: POLY-GLN. 2082..2086
Entrez Domain: POLY-GLN. 2200..2216
Entrez Domain: POLY-GLN. 2296..2299
PFAM bromodomain: Bromodomain 1091..1181
PFAM ZZ: Zinc finger present in dystrophin, C 1702..1743
PRINTS BROMODOMAIN1: Bromodomain motif I - 4 1107..1120
PRINTS BROMODOMAIN2: Bromodomain motif II - 4 1123..1139
PRINTS BROMODOMAIN3: Bromodomain motif III - 4 1139..1157
PRINTS BROMODOMAIN4: Bromodomain motif IV - 4 1157..1176
PRODOM PD024547: CBP(2) P300(1) 1..325
PRODOM PD005214: CBP(2) 344..436
PRODOM PD021760: CBP(2) P300(1) 438..587
PRODOM PD009214: CBP(2) Q19744(2) 589..680
PRODOM PD022334: CBP(2) 682..792
PRODOM PD199912: CBP_MOUSE 794..859
PRODOM PD000651: VL2(74) O18758(34) MUC2(10) 861..1017
PRODOM PD005755: CBP(2) 1019..1049
PRODOM PD201195: CBP_MOUSE 1051..1072
PRODOM PD000747: Q18210(5) Q90941(5) T2D1(4) 1074..1187
PRODOM PD010030: CBP(2) 1189..1553
PRODOM PD009509: CBP(2) CBP1(1) P300(1) 1616..1696
PRODOM PD002686: DMD(3) CBP(2) 1705..1742
PRODOM PD033988: CBP(2) 1761..1843
PRODOM PD030673: CBP(2) 1845..1882
PRODOM PD000540: H1(18) O76786(11) TONB(10) 1884..1959
PRODOM PD001830: HSP1(29) VE2(21) GAG(12) 1964..2215
PRODOM PD022879: CBP(2) P300(1) 2257..2440
__________________
Plus Strand HSPs:
Score = 164 (57.7 bits), Expect = 1.0e-13, Sum P(2) = 1.0e-13
Identities = 36/81 (44%), Positives = 43/81 (53%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD L + DY DI+K PMDL T+K L Y P + DVRL FNNA YN K
Sbjct: 1113 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKT 1172
Query: 186 HDVYTMAEQLLARFEELYRPV 248
VY +L FE+ PV
Sbjct: 1173 SRVYKFCSKLAEVFEQEIDPV 1193
Score = 71 (25.0 bits), Expect = 1.0e-13, Sum P(2) = 1.0e-13
Identities = 23/84 (27%), Positives = 39/84 (46%), Frame = +3
Query: 351 ENPIPPAKLHKEPPPQHPASSSN-----PPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDP 515
+ P PPA+ P PA N PP + S + + + APP P QP P A +
Sbjct: 1902 QTPQPPAQPQPSPVNMSPAGFPNVARTQPPTIVSAGKPTNQVPAPP--PPAQPPPAAVEA 1959
Query: 516 NKR--DMSLEEKHKLGLGLQS-LPPG 584
++ + +++H + + +PPG
Sbjct: 1960 ARQIEREAQQQQHLYRANINNGMPPG 1985
Score = 64 (22.5 bits), Expect = 5.5e-13, Sum P(2) = 5.5e-13
Identities = 21/78 (26%), Positives = 36/78 (46%), Frame = +3
Query: 354 NPIPPAK--LHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRD 527
NP+ P + L +P H + + VR+P+P+++P +P QP P + P+ R
Sbjct: 2311 NPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSP--RPQSQP-PHSS-PSPRI 2366
Query: 528 MSLEEKHKLGLGLQSLPPGL 587
H + + PGL
Sbjct: 2367 QPQPSPHHVSPQTGTPHPGL 2386
Score = 58 (20.4 bits), Expect = 2.3e-12, Sum P(2) = 2.3e-12
Identities = 18/74 (24%), Positives = 34/74 (45%), Frame = +3
Query: 291 EEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASS-SNPPLVQSPVRTPSPMRA 467
+++++ S +P + +++ + P Q A+S SN +PV++P P
Sbjct: 2297 QQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQ 2356
Query: 468 PP---VKPLKQPKP 500
PP P QP+P
Sbjct: 2357 PPHSSPSPRIQPQP 2370
Score = 54 (19.0 bits), Expect = 6.0e-12, Sum P(2) = 6.0e-12
Identities = 11/23 (47%), Positives = 13/23 (56%), Frame = +3
Query: 450 PSPMRAPPVKPLKQPK-PKAKDP 515
PSP APP P +QP P+ P
Sbjct: 1884 PSPTSAPPGTPTQQPSTPQTPQP 1906
Score = 52 (18.3 bits), Expect = 9.6e-12, Sum P(2) = 9.6e-12
Identities = 21/56 (37%), Positives = 27/56 (48%), Frame = +1
Query: 430 CSLRCAHHPQCELLL*SL*SNQS-RRLRTPTRGI*VLKRNTSWG*GCRVCRQGCRVC 597
C H QC SL S Q +R+ T+G KR T+ G GC VC+Q +C
Sbjct: 1776 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGC---KRKTN-G-GCPVCKQLIALC 1827
Score = 42 (14.8 bits), Expect = 1.0e-10, Sum P(2) = 1.0e-10
Identities = 17/75 (22%), Positives = 29/75 (38%), Frame = +3
Query: 249 HEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPL 428
H + I H + + +L + + V ++ P P P Q P++ P
Sbjct: 1849 HNVRQQQIQHCLQ-QAQLMRRRMATMNTRNVPQQSLP-SPTSAPPGTPTQQPSTPQTP-- 1904
Query: 429 VQSPVRT-PSPMRAPP 473
Q P + PSP+ P
Sbjct: 1905 -QPPAQPQPSPVNMSP 1919
>gi|4502453 ref|NP_001717.1| testis-specific bromodomain protein [Homo sapiens]
>gi|2554915|gb|AAB87862.1| (AF019085) BRDT [Homo sapiens]
Length = 947
Frame 3 hits (HSPs): ____________ ___________
__________________________________________________
Database sequence: | | | | | | | | 947
0 150 300 450 600 750 900
Plus Strand HSPs:
Score = 199 (70.1 bits), Expect = 1.2e-13, P = 1.2e-13
Identities = 67/188 (35%), Positives = 88/188 (46%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVDV L LH+Y D++K PMDLGT+K + Y FA+DVRL F N YNP H+
Sbjct: 298 PVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYSFAADVRLMFMNCYKYNPPDHE 357
Query: 192 VYTMAEQLLARFEELY-----RPVHE------KFEGSIVHDRESEEEL--QASSWSQVEP 332
V TMA L FE + PV K + + RE+ E + +S E
Sbjct: 358 VVTMARMLQDVFETHFSKIPIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSED 417
Query: 333 ERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKD 512
ERVK+ AKL ++ H L Q P R + + K K+ K +
Sbjct: 418 ERVKRL------AKLQEQLKAVHQQLQV---LSQVPFRKLNKKKEKSKKEKKKEKVNNSN 468
Query: 513 PNKR----DMSLEEKHK 551
N R M L+EK K
Sbjct: 469 ENPRKMCEQMRLKEKSK 485
Score = 178 (62.7 bits), Expect = 2.2e-11, P = 2.2e-11
Identities = 61/196 (31%), Positives = 92/196 (46%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD V LKL DY IIK PMDL T+K L YA ++ D F+N YN G D
Sbjct: 55 PVDAVKLKLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDD 114
Query: 192 VYTMAEQLLARF-EELYR-PVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIP 365
+ MA+ L F ++L + P E+ G +E ++ + + K+K +P
Sbjct: 115 IVLMAQALEKLFMQKLSQMPQEEQVVGV-------KERIKKGTQQNIAVSSAKEKSSPSA 167
Query: 366 PAKLHK--EPPPQHPASSSNP-PLVQ-SPVRTPSPMRAPPVKPLKQPKPKAKDPNKRDMS 533
K+ K E P P +S +P +VQ + V + S A K +K+ K P +
Sbjct: 168 TEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKR-KADTTTPATSAVK 226
Query: 534 LEEKHKLGLGLQS--LPPGLQSLP 599
+ +S LPP +++P
Sbjct: 227 ASSEFSPTFTEKSVALPPIKENMP 250
>gi|2780777|dbj|BAA24378.1| (AB010247) Ring3 [Mus musculus]
>gi|2780779|dbj|BAA24379.1| (AB010248) Ring3 [Mus musculus]
Length = 503
Frame 3 hits (HSPs): _____________________ ________
__________________________________________________
Database sequence: | | | | | 503
0 150 300 450
Plus Strand HSPs:
Score = 192 (67.6 bits), Expect = 2.4e-13, P = 2.4e-13
Identities = 40/76 (52%), Positives = 45/76 (59%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 328 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 387
Query: 192 VYTMAEQLLARFEELY 239
V MA +L FE Y
Sbjct: 388 VVAMARKLQDVFEFRY 403
Score = 170 (59.8 bits), Expect = 5.9e-11, P = 5.9e-11
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 53 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 112
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 113 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVS 172
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 173 S-VSHTALYT-PPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKK 230
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 231 GVKRKADTTTPTPTAILAPGSPASPPG 257
>gi|4758056 ref|NP_004371.1| CREB binding protein [Homo sapiens]
>gi|3023440|sp|Q92793|CBP_HUMAN CREB-BINDING PROTEIN
>gi|2443859|gb|AAC51770.1| (U47741) CREB-binding protein [Homo
sapiens]
Length = 2442
Frame 3 hits (HSPs): ___ ____ __
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | | 2442
0 500 1000 1500 2000
Plus Strand HSPs:
Score = 156 (54.9 bits), Expect = 2.7e-13, Sum P(2) = 2.7e-13
Identities = 35/81 (43%), Positives = 42/81 (51%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD L + DY DI+K PMDL T+K L Y P + DV L FNNA YN K
Sbjct: 1112 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKT 1171
Query: 186 HDVYTMAEQLLARFEELYRPV 248
VY +L FE+ PV
Sbjct: 1172 SRVYKFCSKLAEVFEQEIDPV 1192
Score = 75 (26.4 bits), Expect = 2.7e-13, Sum P(2) = 2.7e-13
Identities = 24/84 (28%), Positives = 40/84 (47%), Frame = +3
Query: 351 ENPIPPAKLHKEPPPQHPA-----SSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDP 515
+ P PPA+ P PA + + PP S + S + APP P QP P A +
Sbjct: 1901 QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPP--PPAQPPPAAVEA 1958
Query: 516 NKR--DMSLEEKHKLGLGLQ-SLPPG 584
++ + +++H + + S+PPG
Sbjct: 1959 ARQIEREAQQQQHLYRVNINNSMPPG 1984
Score = 67 (23.6 bits), Expect = 1.8e-12, Sum P(2) = 1.8e-12
Identities = 22/78 (28%), Positives = 36/78 (46%), Frame = +3
Query: 354 NPIPPAK--LHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRD 527
NP+ P + L +P H + + VR+P+P+++P +P QP P + P+ R
Sbjct: 2312 NPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSP--RPQSQP-PHSS-PSPRI 2367
Query: 528 MSLEEKHKLGLGLQSLPPGL 587
H + S PGL
Sbjct: 2368 QPQPSPHHVSPQTGSPHPGL 2387
Score = 58 (20.4 bits), Expect = 1.6e-11, Sum P(2) = 1.6e-11
Identities = 18/74 (24%), Positives = 34/74 (45%), Frame = +3
Query: 291 EEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASS-SNPPLVQSPVRTPSPMRA 467
+++++ S +P + +++ + P Q A+S SN +PV++P P
Sbjct: 2298 QQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQ 2357
Query: 468 PP---VKPLKQPKP 500
PP P QP+P
Sbjct: 2358 PPHSSPSPRIQPQP 2371
Score = 54 (19.0 bits), Expect = 4.1e-11, Sum P(2) = 4.1e-11
Identities = 11/23 (47%), Positives = 13/23 (56%), Frame = +3
Query: 450 PSPMRAPPVKPLKQPK-PKAKDP 515
PSP APP P +QP P+ P
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQP 1905
Score = 52 (18.3 bits), Expect = 6.5e-11, Sum P(2) = 6.5e-11
Identities = 21/56 (37%), Positives = 27/56 (48%), Frame = +1
Query: 430 CSLRCAHHPQCELLL*SL*SNQS-RRLRTPTRGI*VLKRNTSWG*GCRVCRQGCRVC 597
C H QC SL S Q +R+ T+G KR T+ G GC VC+Q +C
Sbjct: 1775 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGC---KRKTN-G-GCPVCKQLIALC 1826
Score = 47 (16.5 bits), Expect = 2.2e-10, Sum P(2) = 2.2e-10
Identities = 18/75 (24%), Positives = 30/75 (40%), Frame = +3
Query: 249 HEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPL 428
H+ + I H R + +L + + V ++ P P P Q P++ P
Sbjct: 1848 HKLRQQQIQH-RLQQAQLMRRRMATMNTRNVPQQSLP-SPTSAPPGTPTQQPSTPQTP-- 1903
Query: 429 VQSPVRT-PSPMRAPP 473
Q P + PSP+ P
Sbjct: 1904 -QPPAQPQPSPVSMSP 1918
>gi|12739691 ref|XP_008015.2| CREB binding protein [Homo sapiens]
>gi|4321116|gb|AAC51331.2| (U85962) CREB-binding protein [Homo
sapiens]
Length = 2442
Frame 3 hits (HSPs): ___ ____ __
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | | 2442
0 500 1000 1500 2000
Plus Strand HSPs:
Score = 156 (54.9 bits), Expect = 2.7e-13, Sum P(2) = 2.7e-13
Identities = 35/81 (43%), Positives = 42/81 (51%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD L + DY DI+K PMDL T+K L Y P + DV L FNNA YN K
Sbjct: 1112 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKT 1171
Query: 186 HDVYTMAEQLLARFEELYRPV 248
VY +L FE+ PV
Sbjct: 1172 SRVYKFCSKLAEVFEQEIDPV 1192
Score = 75 (26.4 bits), Expect = 2.7e-13, Sum P(2) = 2.7e-13
Identities = 24/84 (28%), Positives = 40/84 (47%), Frame = +3
Query: 351 ENPIPPAKLHKEPPPQHPA-----SSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDP 515
+ P PPA+ P PA + + PP S + S + APP P QP P A +
Sbjct: 1901 QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPP--PPAQPPPAAVEA 1958
Query: 516 NKR--DMSLEEKHKLGLGLQ-SLPPG 584
++ + +++H + + S+PPG
Sbjct: 1959 ARQIEREAQQQQHLYRVNINNSMPPG 1984
Score = 67 (23.6 bits), Expect = 1.8e-12, Sum P(2) = 1.8e-12
Identities = 22/78 (28%), Positives = 36/78 (46%), Frame = +3
Query: 354 NPIPPAK--LHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRD 527
NP+ P + L +P H + + VR+P+P+++P +P QP P + P+ R
Sbjct: 2312 NPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSP--RPQSQP-PHSS-PSPRI 2367
Query: 528 MSLEEKHKLGLGLQSLPPGL 587
H + S PGL
Sbjct: 2368 QPQPSPHHVSPQTGSPHPGL 2387
Score = 58 (20.4 bits), Expect = 1.6e-11, Sum P(2) = 1.6e-11
Identities = 18/74 (24%), Positives = 34/74 (45%), Frame = +3
Query: 291 EEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASS-SNPPLVQSPVRTPSPMRA 467
+++++ S +P + +++ + P Q A+S SN +PV++P P
Sbjct: 2298 QQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQ 2357
Query: 468 PP---VKPLKQPKP 500
PP P QP+P
Sbjct: 2358 PPHSSPSPRIQPQP 2371
Score = 54 (19.0 bits), Expect = 4.1e-11, Sum P(2) = 4.1e-11
Identities = 11/23 (47%), Positives = 13/23 (56%), Frame = +3
Query: 450 PSPMRAPPVKPLKQPK-PKAKDP 515
PSP APP P +QP P+ P
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQP 1905
Score = 52 (18.3 bits), Expect = 6.5e-11, Sum P(2) = 6.5e-11
Identities = 21/56 (37%), Positives = 27/56 (48%), Frame = +1
Query: 430 CSLRCAHHPQCELLL*SL*SNQS-RRLRTPTRGI*VLKRNTSWG*GCRVCRQGCRVC 597
C H QC SL S Q +R+ T+G KR T+ G GC VC+Q +C
Sbjct: 1775 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGC---KRKTN-G-GCPVCKQLIALC 1826
Score = 47 (16.5 bits), Expect = 2.2e-10, Sum P(2) = 2.2e-10
Identities = 18/75 (24%), Positives = 30/75 (40%), Frame = +3
Query: 249 HEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPL 428
H+ + I H R + +L + + V ++ P P P Q P++ P
Sbjct: 1848 HKLRQQQIQH-RLQQAQLMRRRMATMNTRNVPQQSLP-SPTSAPPGTPTQQPSTPQTP-- 1903
Query: 429 VQSPVRT-PSPMRAPP 473
Q P + PSP+ P
Sbjct: 1904 -QPPAQPQPSPVSMSP 1918
>gi|2780775|dbj|BAA24377.1| (AB010246) Ring3 [Mus musculus]
Length = 549
Frame 3 hits (HSPs): ____________________ ________
__________________________________________________
Database sequence: | | | | | 549
0 150 300 450
Plus Strand HSPs:
Score = 192 (67.6 bits), Expect = 2.9e-13, P = 2.9e-13
Identities = 40/76 (52%), Positives = 45/76 (59%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY DIIK PMDL TVK + Y +FA+DVRL F+N YNP HD
Sbjct: 374 PVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHD 433
Query: 192 VYTMAEQLLARFEELY 239
V MA +L FE Y
Sbjct: 434 VVAMARKLQDVFEFRY 449
Score = 170 (59.8 bits), Expect = 6.9e-11, P = 6.9e-11
Identities = 61/205 (29%), Positives = 88/205 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y ++ D F N YN
Sbjct: 99 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT 158
Query: 186 HDVYTMAEQLLARF-EELYRPVHEKFEGSIVHDRESEEE---LQASSWSQVEPERVKKKE 353
D+ MA+ L F +++ E+ E + + S ++ L A S +V
Sbjct: 159 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVS 218
Query: 354 NPIPPAKLHKEPPPQHPASSSN---PPLVQSPVRTPSPMRAPPV-----KPLKQPKPKAK 509
+ + L+ PPP+ P + N P ++ SP+ PP+ P QP K K
Sbjct: 219 S-VSHTALYT-PPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKK 276
Query: 510 D-PNKRDMSLEEKHK-LGLGLQSLPPG 584
K D + L G + PPG
Sbjct: 277 GVKRKADTTTPTPTAILAPGSPASPPG 303
>gi|737920|prf||1923401A protein CBP [Mus musculus]
Length = 2441
Frame 3 hits (HSPs): ___ ____ __
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | | 2441
0 500 1000 1500 2000
Plus Strand HSPs:
Score = 164 (57.7 bits), Expect = 4.3e-13, Sum P(2) = 4.3e-13
Identities = 36/81 (44%), Positives = 43/81 (53%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD L + DY DI+K PMDL T+K L Y P + DVRL FNNA YN K
Sbjct: 1113 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVRLMFNNAWLYNRKT 1172
Query: 186 HDVYTMAEQLLARFEELYRPV 248
VY +L FE+ PV
Sbjct: 1173 SRVYKFCSKLAEVFEQEIDPV 1193
Score = 65 (22.9 bits), Expect = 4.3e-13, Sum P(2) = 4.3e-13
Identities = 22/84 (26%), Positives = 32/84 (38%), Frame = +3
Query: 351 ENPIPPAKLHKEPPPQHPASSSNPPLVQSP--VRTPSPMRAPPVKPLKQPKPKAKDPNKR 524
+ P PPA+ P PA N Q P V P P P P+ +A R
Sbjct: 1902 QTPQPPAQPQPSPVNMSPAGFPNVARTQPPTIVSAGKPTNQVPAPPPPAPQQQAAVEAAR 1961
Query: 525 DMSLE---EKHKLGLGLQS-LPPG 584
+ E ++H + + +PPG
Sbjct: 1962 QIEREAQQQQHLYRANINNGMPPG 1985
Score = 64 (22.5 bits), Expect = 5.5e-13, Sum P(2) = 5.5e-13
Identities = 21/78 (26%), Positives = 36/78 (46%), Frame = +3
Query: 354 NPIPPAK--LHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRD 527
NP+ P + L +P H + + VR+P+P+++P +P QP P + P+ R
Sbjct: 2311 NPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSP--RPQSQP-PHSS-PSPRI 2366
Query: 528 MSLEEKHKLGLGLQSLPPGL 587
H + + PGL
Sbjct: 2367 QPQPSPHHVSPQTGTPHPGL 2386
Score = 58 (20.4 bits), Expect = 2.3e-12, Sum P(2) = 2.3e-12
Identities = 18/74 (24%), Positives = 34/74 (45%), Frame = +3
Query: 291 EEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASS-SNPPLVQSPVRTPSPMRA 467
+++++ S +P + +++ + P Q A+S SN +PV++P P
Sbjct: 2297 QQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQ 2356
Query: 468 PP---VKPLKQPKP 500
PP P QP+P
Sbjct: 2357 PPHSSPSPRIQPQP 2370
Score = 54 (19.0 bits), Expect = 6.0e-12, Sum P(2) = 6.0e-12
Identities = 11/23 (47%), Positives = 13/23 (56%), Frame = +3
Query: 450 PSPMRAPPVKPLKQPK-PKAKDP 515
PSP APP P +QP P+ P
Sbjct: 1884 PSPTSAPPGTPTQQPSTPQTPQP 1906
Score = 52 (18.3 bits), Expect = 9.6e-12, Sum P(2) = 9.6e-12
Identities = 21/56 (37%), Positives = 27/56 (48%), Frame = +1
Query: 430 CSLRCAHHPQCELLL*SL*SNQS-RRLRTPTRGI*VLKRNTSWG*GCRVCRQGCRVC 597
C H QC SL S Q +R+ T+G KR T+ G GC VC+Q +C
Sbjct: 1776 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGC---KRKTN-G-GCPVCKQLIALC 1827
Score = 42 (14.8 bits), Expect = 1.0e-10, Sum P(2) = 1.0e-10
Identities = 17/75 (22%), Positives = 29/75 (38%), Frame = +3
Query: 249 HEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPL 428
H + I H + + +L + + V ++ P P P Q P++ P
Sbjct: 1849 HNVRQQQIQHCLQ-QAQLMRRRMATMNTRNVPQQSLP-SPTSAPPGTPTQQPSTPQTP-- 1904
Query: 429 VQSPVRT-PSPMRAPP 473
Q P + PSP+ P
Sbjct: 1905 -QPPAQPQPSPVNMSP 1919
>gi|631119|pir||S39162 transcription coactivator CREB-binding protein - human
Length = 2440
Frame 3 hits (HSPs): ___ ____ __
Frame 1 hits (HSPs): __
Annotated Domains: __
__________________________________________________
Database sequence: | | | | | | 2440
0 500 1000 1500 2000
__________________
Annotated Domains:
Entrez domain: bromodomain homology #label BRO 1111..1168
PROSITE BROMODOMAIN_1: Bromodomain signature. 1108..1167
__________________
Plus Strand HSPs:
Score = 156 (54.9 bits), Expect = 7.0e-13, Sum P(2) = 7.0e-13
Identities = 35/81 (43%), Positives = 42/81 (51%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD L + DY DI+K PMDL T+K L Y P + DV L FNNA YN K
Sbjct: 1112 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKT 1171
Query: 186 HDVYTMAEQLLARFEELYRPV 248
VY +L FE+ PV
Sbjct: 1172 SRVYKFCSKLAEVFEQEIDPV 1192
Score = 71 (25.0 bits), Expect = 7.0e-13, Sum P(2) = 7.0e-13
Identities = 23/84 (27%), Positives = 39/84 (46%), Frame = +3
Query: 351 ENPIPPAKLHKEPPPQHPASSSN-----PPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDP 515
+ P PPA+ P PA N PP + S + + + APP P QP P A +
Sbjct: 1901 QTPQPPAQPQPSPVNMSPAGFPNVARTQPPTIVSAGKPTNQVPAPP--PPAQPPPAAVEA 1958
Query: 516 NKR--DMSLEEKHKLGLGLQS-LPPG 584
++ + +++H + + +PPG
Sbjct: 1959 ARQIEREAQQQQHLYRANINNGMPPG 1984
Score = 64 (22.5 bits), Expect = 3.7e-12, Sum P(2) = 3.7e-12
Identities = 21/78 (26%), Positives = 36/78 (46%), Frame = +3
Query: 354 NPIPPAK--LHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPNKRD 527
NP+ P + L +P H + + VR+P+P+++P +P QP P + P+ R
Sbjct: 2310 NPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSP--RPQSQP-PHSS-PSPRI 2365
Query: 528 MSLEEKHKLGLGLQSLPPGL 587
H + + PGL
Sbjct: 2366 QPQPSPHHVSPQTGTPHPGL 2385
Score = 58 (20.4 bits), Expect = 1.6e-11, Sum P(2) = 1.6e-11
Identities = 18/74 (24%), Positives = 34/74 (45%), Frame = +3
Query: 291 EEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASS-SNPPLVQSPVRTPSPMRA 467
+++++ S +P + +++ + P Q A+S SN +PV++P P
Sbjct: 2296 QQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQ 2355
Query: 468 PP---VKPLKQPKP 500
PP P QP+P
Sbjct: 2356 PPHSSPSPRIQPQP 2369
Score = 54 (19.0 bits), Expect = 4.1e-11, Sum P(2) = 4.1e-11
Identities = 11/23 (47%), Positives = 13/23 (56%), Frame = +3
Query: 450 PSPMRAPPVKPLKQPK-PKAKDP 515
PSP APP P +QP P+ P
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQP 1905
Score = 52 (18.3 bits), Expect = 6.5e-11, Sum P(2) = 6.5e-11
Identities = 21/56 (37%), Positives = 27/56 (48%), Frame = +1
Query: 430 CSLRCAHHPQCELLL*SL*SNQS-RRLRTPTRGI*VLKRNTSWG*GCRVCRQGCRVC 597
C H QC SL S Q +R+ T+G KR T+ G GC VC+Q +C
Sbjct: 1775 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGC---KRKTN-G-GCPVCKQLIALC 1826
Score = 42 (14.8 bits), Expect = 7.1e-10, Sum P(2) = 7.1e-10
Identities = 17/75 (22%), Positives = 29/75 (38%), Frame = +3
Query: 249 HEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPL 428
H + I H + + +L + + V ++ P P P Q P++ P
Sbjct: 1848 HNVRQQQIQHCLQ-QAQLMRRRMATMNTRNVPQQSLP-SPTSAPPGTPTQQPSTPQTP-- 1903
Query: 429 VQSPVRT-PSPMRAPP 473
Q P + PSP+ P
Sbjct: 1904 -QPPAQPQPSPVNMSP 1918
>gi|7498991|pir||T33328 hypothetical protein F13C5.2 - Caenorhabditis elegans
>gi|3319395|gb|AAC64610.1| (AF077531) contains similarity to
bromodomains (Pfam: bromodomain.hmm, score: 81.27) [Caenorhabditis
elegans]
Length = 374
Frame 3 hits (HSPs): ___________________
Frame 2 hits (HSPs): _____
__________________________________________________
Database sequence: | | | | 374
0 150 300
Plus Strand HSPs:
Score = 164 (57.7 bits), Expect = 1.1e-12, Sum P(2) = 1.1e-12
Identities = 41/133 (30%), Positives = 66/133 (49%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVDVV L L DY ++IK+PMD+ T++ L Y T +F D +L NN L YN +G
Sbjct: 142 RKPVDVVLLGLTDYHEVIKKPMDMSTIRKKLIGEEYDTAVEFKEDFKLMINNCLTYNNEG 201
Query: 186 HDVYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIP 365
V A Q +F ++ + +G + E+E + + E + K+KE +
Sbjct: 202 DPVADFALQFRKKFAAKWKKEFPE-DGDSFGQEKGEKEGSDNEDDEEEVDE-KEKEEEVK 259
Query: 366 PAKLHKEPP--PQHP 404
++P P+ P
Sbjct: 260 EDNAEEKPAEEPEQP 274
Score = 39 (13.7 bits), Expect = 1.1e-12, Sum P(2) = 1.1e-12
Identities = 9/28 (32%), Positives = 12/28 (42%), Frame = +2
Query: 422 SIGAVSGAHTIPNASSSCEAFEATKAEG 505
++G +SGAH I S A G
Sbjct: 343 ALGEISGAHPIHIGESEIAGHAADSTTG 370
>gi|7291080|gb|AAF46516.1| (AE003448) nej gene product [Drosophila
melanogaster]
Length = 3275
Frame 3 hits (HSPs): __ ___
Frame 1 hits (HSPs): __
__________________________________________________
Database sequence: | | | | | | | | 3275
0 500 1000 1500 2000 2500 3000
Plus Strand HSPs:
Score = 159 (56.0 bits), Expect = 1.3e-12, Sum P(2) = 1.3e-12
Identities = 33/79 (41%), Positives = 46/79 (58%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L + DY +I+K+PMDLGT+++N+ Y+ P ++ DV L F+NA YN K
Sbjct: 1725 PVDPQALGIPDYFEIVKKPMDLGTIRTNIQNGKYSDPWEYVDDVWLMFDNAWLYNRKTSR 1784
Query: 192 VYTMAEQLLARFEELYRPV 248
VY +L FE PV
Sbjct: 1785 VYRYCTKLSEVFEAEIDPV 1803
Score = 68 (23.9 bits), Expect = 1.3e-12, Sum P(2) = 1.3e-12
Identities = 24/83 (28%), Positives = 33/83 (39%), Frame = +3
Query: 363 PPAKLHKEPPPQHPASSSNPPL-----VQSPVRTPSPMRAPPVKPLKQPKP----KAKDP 515
PP H ++ S+PP+ SP PSP AP P QP P + P
Sbjct: 3147 PPTP-HSLQQQLMQSARSSPPIRSPQPTPSPRSAPSPRAAPSASPRAQPSPHHVMSSHSP 3205
Query: 516 NKRDMSLEEKHKLGLGLQSLPPGL 587
+ + H G+ QS PG+
Sbjct: 3206 APQGPPHDGMHNHGMHHQSPLPGV 3229
Score = 38 (13.4 bits), Expect = 1.7e-09, Sum P(2) = 1.7e-09
Identities = 7/33 (21%), Positives = 16/33 (48%), Frame = +3
Query: 420 PPLVQSPVRTPSPMRAPPVKPLKQPKPKAKDPN 518
PP +Q + P++ + + P A++P+
Sbjct: 3102 PPGMQQQQQQQQPLQQQQMMQVAMPNANAQNPS 3134
Score = 38 (13.4 bits), Expect = 1.7e-09, Sum P(2) = 1.7e-09
Identities = 19/61 (31%), Positives = 26/61 (42%), Frame = +1
Query: 415 QILHWCSLRCAHHPQCELLL*SL*SNQSRRLRTP-TRGI*VLKRNTSWG*GCRVCRQGCR 591
Q + C AH QC L S Q +L T+ KR + G GC +C+Q
Sbjct: 2396 QSIQRCIQSLAHACQCRDANCRLPSCQKMKLVVQHTKNC---KRKPN-G-GCPICKQLIA 2450
Query: 592 VC 597
+C
Sbjct: 2451 LC 2452
>gi|1370092|emb|CAA65449.1| (X96669) kinase [Gallus gallus]
Length = 729
Frame 3 hits (HSPs): _____________ ______________
__________________________________________________
Database sequence: | | | | | | 729
0 150 300 450 600
Plus Strand HSPs:
Score = 187 (65.8 bits), Expect = 1.6e-12, P = 1.6e-12
Identities = 60/192 (31%), Positives = 88/192 (45%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY +IIK PMDL T+K + Y +FA+DVRL F+N YNP HD
Sbjct: 322 PVDASALGLHDYHEIIKHPMDLSTIKRKMENRDYHDAQEFAADVRLMFSNCYKYNPPDHD 381
Query: 192 VYTMAEQLLARFEELYRPVHEKFEG----SI------VHDRESEEELQASSWSQVEPERV 341
V MA +L FE Y + ++ + S+ + S EE + + E +
Sbjct: 382 VVAMARKLQDVFEFSYAKMPDEPQDASPPSVSAPLLGALSKSSSEESSSDEDDEDEDDED 441
Query: 342 KKKENPIPPAKLHKEPPPQHPASSSNPPL-VQSPVRTP-SPMRAPPVKPLKQPKPKAKDP 515
++ + E +N +Q +R + A P+ +PK K ++
Sbjct: 442 DDEDESSSESSSDSEESSDSEEERANRLAELQEQLRAVHEQLAALSQGPVSKPKKK-REK 500
Query: 516 NKRDMSLEEKHKLGLG 563
K+ S EKHK G G
Sbjct: 501 KKKKKS--EKHK-GRG 513
Score = 148 (52.1 bits), Expect = 2.5e-08, P = 2.5e-08
Identities = 47/173 (27%), Positives = 74/173 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y A+ D F N YN
Sbjct: 53 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWGAAECMQDFNTMFTNCYIYNKPT 112
Query: 186 HDVYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIP 365
D+ MA+ L F + + + + +V ++ + AS + + + + +
Sbjct: 113 DDIVLMAQTLEKIFLQKVAQMPPEEQEIVVPVAKNSHKKGASRAAGLTAAQQVPAVSSVS 172
Query: 366 PAKLHKEPPP--------QHPASSSNPPLVQSPVRTPSPMRAP-PVKPLKQPK 497
++ P HP+ S P L P+ + AP P +P+ + K
Sbjct: 173 HTAVYTPSPDIATTIVNIPHPSVISAPLLKSLHSTAPAVLTAPAPTQPVAKKK 225
>gi|7512236|pir||T28145 RING3 kinase - chicken >gi|3129967|emb|CAA18965.1|
(AL023516) RING3 kinase [Gallus gallus]
Length = 733
Frame 3 hits (HSPs): _____________ ______________
__________________________________________________
Database sequence: | | | | | | 733
0 150 300 450 600
Plus Strand HSPs:
Score = 187 (65.8 bits), Expect = 1.6e-12, P = 1.6e-12
Identities = 60/192 (31%), Positives = 88/192 (45%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD L LHDY +IIK PMDL T+K + Y +FA+DVRL F+N YNP HD
Sbjct: 326 PVDASALGLHDYHEIIKHPMDLSTIKRKMENRDYHDAQEFAADVRLMFSNCYKYNPPDHD 385
Query: 192 VYTMAEQLLARFEELYRPVHEKFEG----SI------VHDRESEEELQASSWSQVEPERV 341
V MA +L FE Y + ++ + S+ + S EE + + E +
Sbjct: 386 VVAMARKLQDVFEFSYAKMPDEPQDASPPSVSAPLLGALSKSSSEESSSDEDDEDEDDED 445
Query: 342 KKKENPIPPAKLHKEPPPQHPASSSNPPL-VQSPVRTP-SPMRAPPVKPLKQPKPKAKDP 515
++ + E +N +Q +R + A P+ +PK K ++
Sbjct: 446 DDEDESSSESSSDSEESSDSEEERANRLAELQEQLRAVHEQLAALSQGPVSKPKKK-REK 504
Query: 516 NKRDMSLEEKHKLGLG 563
K+ S EKHK G G
Sbjct: 505 KKKKKS--EKHK-GRG 517
Score = 149 (52.5 bits), Expect = 1.9e-08, P = 1.9e-08
Identities = 50/177 (28%), Positives = 75/177 (42%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD V L L DY IIKQPMD+GT+K L N Y A+ D F N YN
Sbjct: 53 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWGAAECMQDFNTMFTNCYIYNKPT 112
Query: 186 HDVYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERVKKKENPIP 365
D+ MA+ L F + + + + +V ++ + AS + + ++ P
Sbjct: 113 DDIVLMAQTLEKIFLQKVAQMPPEEQEIVVPVAKNSHKKGASRAAALLAGLTAAQQVPAV 172
Query: 366 PAKLHKE---PPPQ---------HPASSSNPPLVQSPVRTPSPMRAP-PVKPLKQPK 497
+ H P P HP+ S P L P+ + AP P +P+ + K
Sbjct: 173 SSVSHTAVYTPSPDIATTIVNIPHPSVISAPLLKSLHSTAPAVLTAPAPTQPVAKKK 229
>gi|4557557 ref|NP_001420.1| E1A binding protein p300; p300; E1A-binding
protein, 300kD [Homo sapiens] >gi|3024341|sp|Q09472|P300_HUMAN
E1A-ASSOCIATED PROTEIN P300 >gi|627657|pir||A54277 transcription
adaptor protein p300 - human >gi|495301|gb|AAA18639.1| (U01877)
p300 protein [Homo sapiens]
Length = 2414
Frame 3 hits (HSPs): __ ___ ___
Frame 1 hits (HSPs): ___
__________________________________________________
Database sequence: | | | | | | 2414
0 500 1000 1500 2000
Plus Strand HSPs:
Score = 153 (53.9 bits), Expect = 2.9e-12, Sum P(2) = 2.9e-12
Identities = 34/81 (41%), Positives = 42/81 (51%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD L + DY DI+K PMDL T+K L Y P + D+ L FNNA YN K
Sbjct: 1076 RQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKT 1135
Query: 186 HDVYTMAEQLLARFEELYRPV 248
VY +L FE+ PV
Sbjct: 1136 SRVYKYCSKLSEVFEQEIDPV 1156
Score = 68 (23.9 bits), Expect = 2.9e-12, Sum P(2) = 2.9e-12
Identities = 22/71 (30%), Positives = 31/71 (43%), Frame = +3
Query: 300 LQASSWSQVEPERVKKKENPIP-PAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPP- 473
LQ S V+P + +++ +P A+ Q P S SN PV +P P PP
Sbjct: 2265 LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPH 2324
Query: 474 --VKPLKQPKP 500
P QP+P
Sbjct: 2325 SSPSPRMQPQP 2335
Score = 67 (23.6 bits), Expect = 3.7e-12, Sum P(2) = 3.7e-12
Identities = 25/96 (26%), Positives = 42/96 (43%), Frame = +3
Query: 300 LQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVK 479
LQ S V+P + +++ +P ++ P H P + + VR+P P+ +P +
Sbjct: 2265 LQQQMGSPVQPNPMSPQQHMLP----NQAQSP-HLQGQQIPNSLSNQVRSPQPVPSP--R 2317
Query: 480 PLKQPKPKAKDPNKRDMSLEEKHKLGLGLQSLPPGL 587
P QP P + P+ R H + S PGL
Sbjct: 2318 PQSQP-PHSS-PSPRMQPQPSPHHVSPQTSSPHPGL 2351
Score = 52 (18.3 bits), Expect = 1.3e-10, Sum P(2) = 1.3e-10
Identities = 14/45 (31%), Positives = 15/45 (33%), Frame = +3
Query: 357 PIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQ 491
P P P Q P + P P TP P PP P Q
Sbjct: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTP-PNSMPPYLPRTQ 1891
Score = 51 (18.0 bits), Expect = 1.7e-10, Sum P(2) = 1.7e-10
Identities = 20/56 (35%), Positives = 27/56 (48%), Frame = +1
Query: 430 CSLRCAHHPQCELLL*SL*SNQS-RRLRTPTRGI*VLKRNTSWG*GCRVCRQGCRVC 597
C H QC SL S Q +R+ T+G KR T+ G GC +C+Q +C
Sbjct: 1738 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGC---KRKTN-G-GCPICKQLIALC 1789
Score = 40 (14.1 bits), Expect = 2.3e-09, Sum P(2) = 2.3e-09
Identities = 13/42 (30%), Positives = 17/42 (40%), Frame = +3
Query: 405 ASSSNPPLVQSPVRTPSPMRAPPVKPL-KQPK-PKAKDPNKR 524
AS +V PSP A P P +QP P+ P +
Sbjct: 1833 ASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQ 1874
Score = 39 (13.7 bits), Expect = 2.9e-09, Sum P(2) = 2.9e-09
Identities = 8/28 (28%), Positives = 12/28 (42%), Frame = +3
Query: 357 PIPPAKLHKEPPPQHPASSSNPPLVQSP 440
P+ K + P P ++ PPL P
Sbjct: 1895 PVSQGKAAGQVTPPTPPQTAQPPLPGPP 1922
>gi|11418176 ref|XP_010013.1| E1A binding protein p300 [Homo sapiens]
Length = 2414
Frame 3 hits (HSPs): __ ___ ___
Frame 1 hits (HSPs): ___
__________________________________________________
Database sequence: | | | | | | 2414
0 500 1000 1500 2000
Plus Strand HSPs:
Score = 153 (53.9 bits), Expect = 2.9e-12, Sum P(2) = 2.9e-12
Identities = 34/81 (41%), Positives = 42/81 (51%), Frame = +3
Query: 6 KAPVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKG 185
+ PVD L + DY DI+K PMDL T+K L Y P + D+ L FNNA YN K
Sbjct: 1076 RQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKT 1135
Query: 186 HDVYTMAEQLLARFEELYRPV 248
VY +L FE+ PV
Sbjct: 1136 SRVYKYCSKLSEVFEQEIDPV 1156
Score = 68 (23.9 bits), Expect = 2.9e-12, Sum P(2) = 2.9e-12
Identities = 22/71 (30%), Positives = 31/71 (43%), Frame = +3
Query: 300 LQASSWSQVEPERVKKKENPIP-PAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPP- 473
LQ S V+P + +++ +P A+ Q P S SN PV +P P PP
Sbjct: 2265 LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPH 2324
Query: 474 --VKPLKQPKP 500
P QP+P
Sbjct: 2325 SSPSPRMQPQP 2335
Score = 67 (23.6 bits), Expect = 3.7e-12, Sum P(2) = 3.7e-12
Identities = 25/96 (26%), Positives = 42/96 (43%), Frame = +3
Query: 300 LQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVK 479
LQ S V+P + +++ +P ++ P H P + + VR+P P+ +P +
Sbjct: 2265 LQQQMGSPVQPNPMSPQQHMLP----NQAQSP-HLQGQQIPNSLSNQVRSPQPVPSP--R 2317
Query: 480 PLKQPKPKAKDPNKRDMSLEEKHKLGLGLQSLPPGL 587
P QP P + P+ R H + S PGL
Sbjct: 2318 PQSQP-PHSS-PSPRMQPQPSPHHVSPQTSSPHPGL 2351
Score = 52 (18.3 bits), Expect = 1.3e-10, Sum P(2) = 1.3e-10
Identities = 14/45 (31%), Positives = 15/45 (33%), Frame = +3
Query: 357 PIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPSPMRAPPVKPLKQ 491
P P P Q P + P P TP P PP P Q
Sbjct: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTP-PNSMPPYLPRTQ 1891
Score = 51 (18.0 bits), Expect = 1.7e-10, Sum P(2) = 1.7e-10
Identities = 20/56 (35%), Positives = 27/56 (48%), Frame = +1
Query: 430 CSLRCAHHPQCELLL*SL*SNQS-RRLRTPTRGI*VLKRNTSWG*GCRVCRQGCRVC 597
C H QC SL S Q +R+ T+G KR T+ G GC +C+Q +C
Sbjct: 1738 CIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGC---KRKTN-G-GCPICKQLIALC 1789
Score = 40 (14.1 bits), Expect = 2.3e-09, Sum P(2) = 2.3e-09
Identities = 13/42 (30%), Positives = 17/42 (40%), Frame = +3
Query: 405 ASSSNPPLVQSPVRTPSPMRAPPVKPL-KQPK-PKAKDPNKR 524
AS +V PSP A P P +QP P+ P +
Sbjct: 1833 ASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQ 1874
Score = 39 (13.7 bits), Expect = 2.9e-09, Sum P(2) = 2.9e-09
Identities = 8/28 (28%), Positives = 12/28 (42%), Frame = +3
Query: 357 PIPPAKLHKEPPPQHPASSSNPPLVQSP 440
P+ K + P P ++ PPL P
Sbjct: 1895 PVSQGKAAGQVTPPTPPQTAQPPLPGPP 1922
>gi|7504519|pir||T22845 hypothetical protein F57C7.1a - Caenorhabditis elegans
>gi|3877720|emb|CAA93473.1| (Z69646) contains similarity to Pfam
domain: PF00439 (Bromodomain), Score=272.5, E-value=1.8e-78,
N=3~cDNA EST CEESD87F comes from this gene~cDNA EST EMBL:T01317
comes from this gene~cDNA EST EMBL:T02106 comes from this gene~cDNA
EST yk27b3.3 comes fro>
Length = 1250
Frame 3 hits (HSPs): ____ __________ __
__________________________________________________
Database sequence: | | | | | | | | | | 1250
0 150 300 450 600 750 900 1050 1200
Plus Strand HSPs:
Score = 175 (61.6 bits), Expect = 3.3e-12, Sum P(2) = 3.3e-12
Identities = 37/110 (33%), Positives = 59/110 (53%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + LK++DY ++I PMDL T+K L YA P +F D+ L +N YNPKG
Sbjct: 622 PVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSP 681
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERV 341
++ A +L + FE+ ++ I+ D + L ++ +E ER+
Sbjct: 682 AHSNALELRSFFEQRWKLFPRPGVDPIIADSYINQNLVVNT-DLIEDERI 730
Score = 129 (45.4 bits), Expect = 3.8e-08, Sum P(2) = 3.8e-08
Identities = 28/81 (34%), Positives = 45/81 (55%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L++ +Y +I+ PMDL T++ L Y D D+ F N ++NP +D
Sbjct: 310 PVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYD 369
Query: 192 VYTMAE----QLLARFEELYR 242
VY MA+ Q+L++ +L R
Sbjct: 370 VYKMAKTLEKQVLSQLTQLPR 390
Score = 72 (25.3 bits), Expect = 3.8e-08, Sum P(2) = 3.8e-08
Identities = 26/90 (28%), Positives = 45/90 (50%), Frame = +3
Query: 279 DRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPS- 455
D +E++ ++ + S V+PE V E P P +PP + + + P V + TP+
Sbjct: 507 DTATEKDAESRAES-VQPEVVN--EEPKPSTS---QPPSKKRKAENGEPAVAVKIATPAT 560
Query: 456 PMRAPPVKPLKQPKPKAKDPNKRDMSLEEKH 548
P+ A P ++ P+ K+PN +E KH
Sbjct: 561 PVAAHP----QEETPRRKNPNTL---IEWKH 584
Score = 39 (13.7 bits), Expect = 3.3e-12, Sum P(2) = 3.3e-12
Identities = 7/19 (36%), Positives = 11/19 (57%), Frame = +3
Query: 489 QPKPKAKDPNKRDMSLEEK 545
+PKP+AK P + +K
Sbjct: 1125 EPKPQAKKPEPPQKKVAKK 1143
>gi|6320132 ref|NP_010213.1| Bromodomain protein, homolog of Bdf1; Bdf2p
[Saccharomyces cerevisiae] >gi|2131324|pir||S67605 hypothetical
protein YDL070w - yeast (Saccharomyces cerevisiae)
>gi|1431082|emb|CAA98636.1| (Z74119) ORF YDL070w [Saccharomyces
cerevisiae]
Length = 638
Frame 3 hits (HSPs): _______ ________
__________________________________________________
Database sequence: | | | | | | 638
0 150 300 450 600
Plus Strand HSPs:
Score = 176 (62.0 bits), Expect = 2.0e-11, P = 2.0e-11
Identities = 36/103 (34%), Positives = 62/103 (60%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L L +Y D++K PMDLGT+ +NL Y T F D+ L F N +NP+G++
Sbjct: 348 PVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNE 407
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWS 320
V++M ++L +EL+ H I+++ E++ +L+ ++S
Sbjct: 408 VHSMGKKL----KELFN-FHWLENQDILNEIETDSDLEEDNYS 445
Score = 111 (39.1 bits), Expect = 0.0089, P = 0.0088
Identities = 22/74 (29%), Positives = 40/74 (54%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L + Y + ++ PMDL +++ L NVY + SD + +N L +N
Sbjct: 161 PVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESS 220
Query: 192 VYTMAEQLLARFEE 233
+ +MA+++ FE+
Sbjct: 221 ISSMAKRIQKYFEK 234
>gi|7504520|pir||T22847 hypothetical protein F57C7.1b - Caenorhabditis elegans
>gi|3877722|emb|CAA93475.1| (Z69646) contains similarity to Pfam
domain: PF00439 (Bromodomain), Score=245.7, E-value=1.6e-70,
N=2~cDNA EST yk85e11.3 comes from this gene~cDNA EST yk85e11.5
comes from this gene~cDNA EST yk87g8.3 comes from this gene~cDNA
EST yk68g3.3 comes from th>
Length = 1087
Frame 3 hits (HSPs): ____ ____ ______
__________________________________________________
Database sequence: | | | | | | | | | 1087
0 150 300 450 600 750 900 1050
Plus Strand HSPs:
Score = 175 (61.6 bits), Expect = 5.4e-11, P = 5.4e-11
Identities = 37/110 (33%), Positives = 59/110 (53%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + LK++DY ++I PMDL T+K L YA P +F D+ L +N YNPKG
Sbjct: 582 PVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSP 641
Query: 192 VYTMAEQLLARFEELYRPVHEKFEGSIVHDRESEEELQASSWSQVEPERV 341
++ A +L + FE+ ++ I+ D + L ++ +E ER+
Sbjct: 642 AHSNALELRSFFEQRWKLFPRPGVDPIIADSYINQNLVVNT-DLIEDERI 690
Score = 119 (41.9 bits), Expect = 7.2e-07, Sum P(2) = 7.2e-07
Identities = 22/68 (32%), Positives = 36/68 (52%), Frame = +3
Query: 12 PVDVVGLKLHDYCDIIKQPMDLGTVKSNLSKNVYATPADFASDVRLTFNNALAYNPKGHD 191
PVD + L++ +Y +I+ PMDL T++ L Y D D+ F+N +N + D
Sbjct: 310 PVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDLNTLFDNCKKFNDRNDD 369
Query: 192 VYTMAEQL 215
+Y M E +
Sbjct: 370 IYIMCENI 377
Score = 72 (25.3 bits), Expect = 7.2e-07, Sum P(2) = 7.2e-07
Identities = 26/90 (28%), Positives = 45/90 (50%), Frame = +3
Query: 279 DRESEEELQASSWSQVEPERVKKKENPIPPAKLHKEPPPQHPASSSNPPLVQSPVRTPS- 455
D +E++ ++ + S V+PE V E P P +PP + + + P V + TP+
Sbjct: 467 DTATEKDAESRAES-VQPEVVN--EEPKPSTS---QPPSKKRKAENGEPAVAVKIATPAT 520
Query: 456 PMRAPPVKPLKQPKPKAKDPNKRDMSLEEKH 548
P+ A P ++ P+ K+PN +E KH
Sbjct: 521 PVAAHP----QEETPRRKNPNTL---IEWKH 544
WARNING: HSPs involving 760 database sequences were not reported due to the
limiting value of parameter B = 50.
Parameters:
filter=none
matrix=BLOSUM62
V=50
B=50
E=10
gi
H=1
sort_by_pvalue
echofilter
ctxfactor=5.97
Query ----- As Used ----- ----- Computed ----
Frame MatID Matrix name Lambda K H Lambda K H
Std. 0 BLOSUM62 0.318 0.135 0.401
+3 0 BLOSUM62 0.311 0.131 0.385 same same same
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+2 0 BLOSUM62 0.318 0.135 0.401 0.357 0.156 0.549
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+1 0 BLOSUM62 0.318 0.135 0.401 0.358 0.155 0.606
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-1 0 BLOSUM62 0.318 0.135 0.401 0.331 0.144 0.475
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-2 0 BLOSUM62 0.318 0.135 0.401 0.333 0.140 0.482
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-3 0 BLOSUM62 0.318 0.135 0.401 0.344 0.151 0.533
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
Query
Frame MatID Length Eff.Length E S W T X E2 S2
+3 0 199 198 10. 76 3 12 23 0.11 35
31 0.10 38
+2 0 200 199 10. 77 3 12 22 0.093 35
31 0.10 38
+1 0 200 199 10. 77 3 12 22 0.093 35
31 0.10 38
-1 0 200 199 10. 77 3 12 22 0.093 35
31 0.10 38
-2 0 200 199 10. 77 3 12 22 0.093 35
31 0.10 38
-3 0 199 199 10. 77 3 12 22 0.093 35
31 0.10 38
Statistics:
Database: /usr/local/dot5/sl_home/beauty/seqdb/blast/nr
Title: nr
Release date: unknown
Posted date: 4:06 PM CST Feb 28, 2001
Format: BLAST
# of letters in database: 197,782,623
# of sequences in database: 625,274
# of database sequences satisfying E: 810
No. of states in DFA: 590 (58 KB)
Total size of DFA: 231 KB (256 KB)
Time to generate neighborhood: 0.02u 0.00s 0.02t Elapsed: 00:00:00
No. of threads or processors used: 6
Search cpu time: 235.80u 1.09s 236.89t Elapsed: 00:00:50
Total cpu time: 235.93u 1.12s 237.05t Elapsed: 00:00:51
Start: Mon Feb 4 09:09:28 2002 End: Mon Feb 4 09:10:19 2002
WARNINGS ISSUED: 2
Annotated Domains Database: March 14, 2000
Release Date: March 14, 2000