Chiasson MA, Wright TC, Ellerbrock TV, Young S, Marte C; National Conference on Human Retroviruses and Related Infections.
Program Abstr First Natl Conf Hum Retrovir Relat Infect Natl Conf Hum Retrovir Relat Infect 1st 1993 Wash DC. 1993 Dec 12-16; 98.
New York City Department of Health, NY.
Objective: To determine the prevalence of human papilloma virus associated vulvovaginal disease in HIV-positive and a comparable group of HIV-negative women. Methods: All participants received a complete gynecologic examination, including a colposcopic evaluation and a structured interview emphasizing demographics and risk factors for vulvovaginal disease. Results: Vulvar or vaginal condyloma acuminatum were detected in 22 (6%) of 398 HIV-positive and in 3 (1%) of 357 HIV-negative women (OR=6.9, p less than 0.001). Involvement of both the vulva and vagina occurred in 3 of the HIV-positive, but none of the HIV-negative women. Among HIV-positive women, condyloma were detected in 3% of 109 with greater than 500 CD4+ cells/microliter, 5% of 125 women with 200-500 CD4+ cells/microliter, and 11% of 95 with less than 200 CD4+ cells/microliter (p=0.02). Vulvar intraepithelial neoplasia (VIN) was documented in 2 of the HIV-positive and none of the HIV-negative women (p=0.28). Conclusion: The prevalence of vulvovaginal condyloma is increased in HIV-positive women. Because VIN is uncommon, its detection in this population suggests that HIV-positive women may be at increased risk for developing invasive vulvar carcinoma.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Carcinoma in Situ
- Condylomata Acuminata
- Female
- HIV Infections
- HIV Seropositivity
- Humans
- Neoplasms, Squamous Cell
- Papillomaviridae
- Prevalence
- Risk Factors
- Vaginal Diseases
- Vulvar Neoplasms
Other ID:
UI: 102214207
From Meeting Abstracts