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Pressure Control in BSL-3 Laboratories

Adam R. Bare, PE, Newcomb & Body

For reliable and constant containment in BSL-3 laboratories, HVAC and laboratory controls systems must be designed to ensure that pressure relationships are continuously maintained. The term "relationship" is key to this issue because the magnitude of the differential pressure is irrelevant in a BSL-3 environment. The intent is to ensure that airflow is always traveling in the correct direction (given the premise that contaminants are not capable of traveling upstream).

In the past, designers of BSL-3 facilities have used differential pressures on the order of 0.05" wg, or even as high as 0.1" wg or more. This presentation will offer real world examples of what those differential pressures equate to, as well as explain that differential pressures of those magnitudes were applicable to controls systems of the past. They are no longer necessary. Much lower differential pressures, in the range of 0.005"-0.01" wg, are more applicable when using today's faster, more accurate controls devices.

Another concern is the level to which the systems are automated because the more systems need to sense and respond, the faster, more reliable, and smarter the controls systems need to be. This presentation will go on to explain actual applications of those controls in a BSL-3 facility, and provide a simplistic approach to configuring the HVAC and controls systems so as to ensure that pressure relationships are maintained regardless of what is happening either inside or outside of the building (such as doors opening or closing, strong winds blowing against exterior walls, etc.)

Labs21 Connection:

Designers of BSL-3 facilities are concerned about using lower differential pressures because any breach in containment has direct implications on life safety. BSL-3 laboratories are typically designed to have a series of cascading pressures from more-to-less contaminated areas. With cascading pressures starting at zero and incrementally increasing as one approaches the entry areas, the static pressures in the entry areas can be quite high. The higher differentials can yield over-pressurization of front entry areas, air turbulence, eddy currents, and nuisance issues. Therefore, differential pressures should be maintained at the lowest possible magnitude that can be reliably controlled. Not only does this create a more comfortable and usable environment, but the reduction in pressure also allows the amount of exhaust to be reduced. Lowering the exhaust lowers the outside air requirements. The HVAC systems will get smaller and use less energy—a fundamental aspect of the Labs21 Approach.

Using constant air volume systems in containment areas and variable air volume systems in entryways and corridors is a simplistic approach to configuring lab systems geared towards minimizing the amount of automation. The primary goal is to reliably control containment throughout the life of the facility. Contrary to typical laboratory design, this approach does not require complicated and expensive airflow controls systems, leaving the owner with a facility that reliably sustains its pressure profile.

Biography:

Adam Bare earned his bachelor of mechanical engineering degree from the Georgia Institute of Technology in 1997 and an MBA from Georgia State University in 2001. During his eight years with Newcomb & Boyd, he has developed a particular expertise in the design of mechanical systems for laboratory and research facilities. Mr. Bare's experience includes laboratory projects for Georgia Public Health, East Carolina University, University of Alabama, and the Medical University of South Carolina. His work totals more than one million square feet and over $175 million in construction value.

 

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