Bibliographic Citation
| Document | For copies of Journal Articles, please contact the Publisher or your local public or university library and refer to the information in the Resource Relation field. For copies of other documents, please see the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or Document Availability. |
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| Title | Beyond estrogens: Why unmasking hormone-mimicking pollutants proves so challenging |
| Creator/Author | Raloff, J. |
| Publication Date | 1995 Jul 15 |
| OSTI Identifier | OSTI ID: 103438 |
| Other Number(s) | SCNEBK; ISSN 0036-8423 |
| Resource Type | Journal Article |
| Resource Relation | Science News ; VOL. 148 ; ISSUE: 3 ; PBD: 15 Jul 1995 |
| Subject | 54 ENVIRONMENTAL SCIENCES ; POLYCHLORINATED BIPHENYLS; BIOLOGICAL EFFECTS; ANIMALS; REPRODUCTIVE DISORDERS; MAN |
| Description/Abstract | EPA`s new computer models of androgens and estrogens correctly predicted that two common PCBs would have little or no affinity for sex hormone receptors but that the third common PCB would. Concerns that pseudoestogens may underlie an apparent breast cancer epidemic in women may be too simplistic however. EPA scientists have now identified a host of pollutants that functionally mimic estrogens in animals yet act through a nonestrogenic pathway by blocking male sex hormones. This article summarizes this and other studies on hormonal reprecussions of environmental toxins, including studies of molecular structure and animal studies. |
| Country of Publication | United States |
| Language | English |
| Format | pp. 44-46 ; PL: |
| System Entry Date | 2001 May 03 |
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Last Updated: 02/10/2009