Vinogradova VA; International Conference on AIDS.
Int Conf AIDS. 2002 Jul 7-12; 14: abstract no. ThPeB7374.
St.Petersburg, Russian Federation
BACKGROUND: Oral cavity is often both a common site of infection among immunodeficient persons and often a source of considerable discomfort. Oral infections tend to be recurrent, severe, sometimes resistant to treatment and may spread systemically from the mouth. Microbial flora is highly complex. METHODS: We examined 27 patients, 21 males and 4 females, who were on treatment at infections diseases hospital. 19 of the 27 patients were intravenous drug users, who got infectected parenterally, the others were infected via sexual route. The age of eleven patients was from 17 to 25, the other age group was from 25 to50 years old.12 of the examined patients had viral hepatitis C or B or B and C, 2 had septical endocarditis and pnemonia. We took bacteriological test of smears from the tongue and mucous. RESULTS: On careful examination of the oral cavity of HIV infected drug users we found that 16 persons had hyperemia, 11 had ulcers, haemorrahage spots, white leasons of thrush on cheeks, palate of the mucous, 3 had hairy leukoplakia. These three patients had AIDS and CD 4 T-cells were less than 200 mm3. Some appeared to have no manifestation, but according to results of their smears showed N.albicans. In all persons Candida albicans was revealed, in addition six had P.aeroginosa, S.pyogenes, E.coli, Klebsiella. However, it would only just to say that all of them had poor oral hygiene. During talks everyone of the group admitted that they did not clean their teeth regularly and did not use additional cleaning material. Due to it oral manifestations were severe and recurrent. We did not find the correlation between viral load and oral manifestations. But patients who had viral load more than 1mil cop.RNA.HIV/ml plasma had manifestations and disseminated candidasis. CONCLUSION: Poor and non-regular care of oral cavity increase colonization of wide variety of microorganisms and leads to oral manifestations especially among HIV infected persons.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Candidiasis, Oral
- Dental Caries
- Female
- HIV Infections
- HIV Seropositivity
- Humans
- Leukoplakia, Hairy
- Male
- Mouth Diseases
- Substance Abuse, Intravenous
- Viral Load
Other ID:
UI: 102250523
From Meeting Abstracts