Chemical Sampling Information
	n-Propoxypropanol (mixed isomers)
Quick Links General Description Health Factors Search    [use word(s)/phrase ] Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number General Description Synonyms: PnP; 1-Propoxy-2-propanol; Propylene glycol monopropyl ether; propylene glycol mono-n-propyl ether; propyl propasol; Dowanol®; Propasol P OSHA IMIS Code Number: P202 Chemical Abstracts Service (CAS) Registry Number: 30136-13-1 Related Chemical Abstracts Service (CAS) Registry Number: 1569-01-3 (1-Propoxy-2-propanol) NIOSH, Registry of Toxic Effects (RTECS) Identification Number: UB9351000 Typical Mixture Description and Physical Properties: clear, colorless flammable liquid molecular formula: C6H14O2 molecular weight: 116.2 boiling point: 149°C flash point: 48°C Health Factors Potential symptoms: In animals: eye and skin irritation (blepharospasm, lacrimation, conjunctival hyperemia; narcosis (ataxia, loss of righting reflex) Health Effects: Irritation-Eyes---Marked (HE14); Irritation Skin---Moderate (HE15); Narcosis (HE8) Affected organs: Eyes, skin, CNS. Notes: OSHA does not have a PEL for any isomers of this chemical. Gross pathology of animals dying from high oral (rats) or percutaneous (rabbits) doses of 1-propoxy-2-propanol showed dark red lungs. Oral LD50s were 4.92 ml/kg (males) and 2.83 ml/kg (females). Percutaneous LD50s were 4.29 ml/kg (males) and 4.92 ml/kg (females). No fatalities occurred among 10 rats (5 male, 5 female) exposed for 6-hours to a saturated vapor atmosphere (~2230 ppm) of 1-propoxy-2-propanol, but showed signs of eye irritation and narcosis. 1-Propoxy-2-propanol is one of the 30 “predominant” VOCs identified by NIOSH in at least one area of a microwave popcorn plant which had eight former workers diagnosed with bronchiolitis obliterans. It is not known whether 1-propoxy-2-propanol contributed to the cause of this lung disease. Date Last Revised: 05/15/2006 Literature Basis: Ballantyne, B., Myers, R.C. and Losco, P.E.: The acute toxicity and primary irritancy of 1-propoxy-2-propanol. Vet. Hum. Toxicol. 30(2): 126-129, 1988. Gomaa, A., et al.: NIOSH Investigation of Gilster Mary Lee, HETA #2000-0401, Technical Assistance to Missouri Department of Health. Interim Report, August 22, 2001, 46 pp. All Trademarks are the property of their respective owners.