Phase 3 Safety Results
Adverse Event Vehicle 0.05% CsA 0.1% CsA n = 292 n = 293 n = 292
Burning Eye 7.2 % 16.0 % 17.5 %
Discharge Eye 2.7 % 4.8 % 2.4 %
Foreign Body Sensation 2.7 % 3.8 % 2.4 %
Conjunctival Hyperemia 0.7 % 3.8 % 4.1 %
Stinging Eye 1.7 % 3.4 % 4.8 %
Irritation Eye 1.7 % 3.1 % 1.7 %
Visual Disturbance 6.2 % 3.1 % 5.1 %
Pruritus Eye 3.4 % 2.7 % 4.5 %
Photophobia 1.0 % 2.4 % 3.1 %
Eye Pain 2.7 % 1.7 % 5.8 %
Number (%) of Patients with Ocular Adverse Events Reportedby ? 3% of Patients (n=9) in Either CsA Group