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UNIVERSITY OF CALIFORNIA, DAVIS ,,*

SANTA BARBARA SANTA CRUZ

BERKELEY * DAVIS * IRVINE - LOS ANGELES - RIVERSIDE * SAN DIEGO - SAN FRANCISCO

DEPARTMENT OF BIOCHEMISTRY

AND BIOPHYSICS

DAVIS, CALIFORNIA 95616

July 1, 1965

Dear Sol :

   Greetings from God's country! After a long journey
aoross the country we have finally settled down a bit. My
lab is still in the process of getting organized, but with-
in two weeks our work should be proceeding at its usual rate.

  There is one question that I would like to ask. In your
studies on hybrid fomation between ribosomal RNA and DNA,
you found that B. megaterium €3-RNA did not hybridize with E.
- coli DNA.
that it will hybridize with E. coli and Prot. vu1 aris DNA

Hall membrane method.  However, B. subtilis R-RNA does not
hybridize with - Ps. aeruginosa DNA under any condition.  Did you
ever try hybridizing your megaterium R-RNA with any other
specie(s)?  We are finding some very interesting results with
interspecies hybridization particulargy with R-RNA.  The M-RNA
has not been conserved among Bacillus species glcoording to our
results.

In OE studies with B. subtilis B-RNA we are finding

when assayed by the Hall-Spieges SWB method + and he Nygaard-

Also I would appreciate receiving a couple more reprints

Of the paper in the Regulation Symposium at Marseilles,  if still
available. Thank you.

   Since we are building a home, I hope you will be able to
visit us sometime in the near future. I hope you will let me
know when you visit the West Coast in order that I may set up
a visit for you.

With best regards,

Sincerely yours ,