National Heart, Lung, and Blood Institute Division of Intramural Research
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Fly Embryo RNAi Project
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Heart Gene: CG12370


 
CG Number: CG12370
Full Name: CG12370
Symbol: CG12370
Molecular Function: neuropeptide receptor activity; neuropeptide hormone activity; diuretic hormone receptor activity; secretin-like receptor activity
Phenotype: Heart
FlyBase Record  


Fly Embryo Images Showing Heart Phenotype Mutation
Fly embryo images showing heart phenotype mutation

An individual dsRNA was injected into the embryo that harbors a beta-galactosidase (ß-gal) marker gene. This gene is expressed in the cardial cells and a subset of ventral muscle founder cells. By X-gal staining followed by monitoring of the ß-gal expression pattern and heart morphology in injected embryos, a cardiogenic gene is identified. Further characterization of the injected embryos by immunostaining with specific antibodies was also performed.

The brightfield image here shows the phenotype resulted from silencing of the gene by an injected dsRNA.

Click "download image" below to copy the image locally onto you hard drive. The image file downloaded is in TIFF format.

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Department of Health and Human Services National Institutes of Health National Heart, Lung, and Blood Institute
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Fly Embryo RNAi Project (Version 2.10)