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Actinobacillus actinomycetemcomitans Search Results

Record: 1 of 1  
MiniMap IGR0850 IGR0849 IGR0847 IGR0851 IGR0846 IGR0852 IGR0848 comD, - AA01298 comC, - AA01299 aroK,aroL,aroE, - AA01296 comA, - AA01303 aroB, - AA01295 comE, - AA01297 uvrA, - AA01291 ssb, - AA01292 ponA,pbp1A,mrcA, - AA01304 comD, - AA01298 comC, - AA01299 aroK,aroL,aroE, - AA01296 comA, - AA01303 aroB, - AA01295 comE, - AA01297 uvrA, - AA01291 ssb, - AA01292 ponA,pbp1A,mrcA, - AA01304 comD, - AA01298 comC, - AA01299 aroK,aroL,aroE, - AA01296 comA, - AA01303 aroB, - AA01295 comE, - AA01297 uvrA, - AA01291 comB, - AA01301 dam, - AA01294 comB, - AA01301 dam, - AA01294 ssb, - AA01292 ponA,pbp1A,mrcA, - AA01304


Gene ID:AA01297

DNA Molecule Name:
1  

GenBank ID:


Gene Name:
comE  

Definition:
competence protein E precursor

Cellular Location:
Outer membrane, Periplasm, Cytoplasm [Evidence]

Gene Start:
880671

Gene Stop:
879265

Gene Length:
1407

Molecular Weight*:
51723

pI*:


Net Charge*:


EC:
 

Functional Class:
Cellular processes; Transformation  

Gene Ontology:
Biological process
  GO:0009297    pilus biogenesis
  GO:0009306    protein secretion

Cellular component
  GO:0016020    membrane


Pathway: pathway table

Secondary Evidence:
Ween O, Teigen S, Gaustad P, Kilian M, Havarstein LS.
Competence without a competence pheromone in a natural isolate of Streptococcus infantis.
J Bacteriol. 2002 Jul;184(13):3426-32.
PMID: 12057935


Chen I, Gotschlich EC.
ComE, a competence protein from Neisseria gonorrhoeae with DNA-binding activity.
J Bacteriol. 2001 May;183(10):3160-8.
PMID: 11325945

Busch S, Rosenplanter C, Averhoff B.
Identification and characterization of ComE and ComF, two novel pilin-like competence factors involved in natural transformation of Acinetobacter sp. strain BD413.
Appl Environ Microbiol. 1999 Oct;65(10):4568-74.
PMID: 10508090

Comment:


View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|152978367|ref|YP_001343996.1|  type IV pilus secretin Pil...   584   e-165
 gi|145628805|ref|ZP_01784605.1|  competence protein E [Haemo...   584   e-165
 gi|148827632|ref|YP_001292385.1|  competence protein E [Haem...   583   e-164
 gi|145634568|ref|ZP_01790277.1|  competence protein E [Haemo...   580   e-164
 gi|16272383|ref|NP_438596.1|  competence protein E [Haemophi...   580   e-164
 gi|145636296|ref|ZP_01791965.1|  competence protein E [Haemo...   578   e-163
 gi|145640400|ref|ZP_01795984.1|  competence protein E [Haemo...   577   e-163
 gi|145630388|ref|ZP_01786169.1|  competence protein E [Haemo...   577   e-163
 gi|52426025|ref|YP_089162.1|  GspD protein [Mannheimia succi...   575   e-162
 gi|148997|gb|AAA25012.1|  A mini-Tn10kan insertion in ORF E ...   573   e-162


InterPro Summary:  InterProScan

InterPro
IPR001775
Domain
Bacterial general secretion pathway protein D
PR00811 [195-205]T 2.9e-17 PR00811 BCTERIALGSPD[273-297]T 2.9e-17 PR00811 BCTERIALGSPD[401-419]T 2.9e-17 PR00811 BCTERIALGSPD[424-438]T 2.9e-17 PR00811 BCTERIALGSPD BCTERIALGSPD
InterPro
IPR001814
Family
Filamentous bacteriophage Vg4 protein
PR01032 [257-280]T 8e-08 PR01032 PHAGEIV[298-321]T 8e-08 PR01032 PHAGEIV[364-392]T 8e-08 PR01032 PHAGEIV[417-439]T 8e-08 PR01032 PHAGEIV PHAGEIV
InterPro
IPR003833
Domain
Allophanate hydrolase subunit 1
SM00796 [127-271]T 4.7e+02 SM00796 no description no description
InterPro
IPR004846
Domain
Bacterial type II and III secretion system protein
PF00263 [197-437]T 1.4e-87 PF00263 Secretin Secretin
InterPro
IPR005644
Domain
NolW-like
PF03958 [130-195]T 2.7e-13 PF03958 Secretin_N Secretin_N
InterPro
IPR013355
Family
Type IV pilus secretin PilQ
TIGR02515 [28-437]T 5e-157 TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ IV_pilus_PilQ: type IV pilus secretin PilQ
noIPR
unintegrated
unintegrated
signalp [1-25]? NA signalp signal-peptide signal-peptide


COGS Summary:  COGS Search
No hits to the COGs database.
Blocks Summary:  Blocks Search

Significant hit ( 1.5e-51) to 3/3 blocks of the IPB000016 family, which is described as "General (type II) secretion pathway (GSP) D protein". Interpro entry for IPR000016.
    IPB000016A    186-217    6.5e-14
    IPB000016B    275-310    8e-14
    IPB000016C    375-416    4e-21
Significant hit ( 2.1e-05) to 2/8 blocks of the PR01337 family, which is described as "Type III secretion system outer membrane G protein family signature". Prints database entry for PR01337.
    PR01337E    197-217    0.00025
    PR01337H    415-434    42

 ProDom Summary:  Protein Domain Search

Residues 382 to 437 match (5e-07) PD:PD525573 which is described as PROTEOME COMPLETE PROBABLE PLASMID II SYSTEM TYPE SECRETION MSHL HEMAGGLUTININ

Paralogs:  Local Blast Search

AA01297 is paralogously related to AA00871 (rough colony protein A) (2e-18).


Pfam Summary:  Pfam Search

Residues 197 to 437 (E-value = 1.3e-87) place AA01297 in the Secretin_C family which is described as Bacterial type II and III secretion system protein (PF00263)


 Structural Feature(s):
Feature Type  Start  Stop
Cleavable N-term signal seq  
1  
25

Top PDB Hits:


Gene Protein Sequence:
MKSILSRRLKCGLFFGCFLSLAVQAEQNPVFSIRLKQAPLVPTLQQLALA
HNTNLIIDDELQGTVSLQLENVDLDQLFRSVAKIKQLDLWQENGIYYFTK
GDTNTKFAGKMEEPFPLSLPMAEEPAQLNTATIKLHFAKASEVMKSLTGG
SGSLLSPNGSITFDDRSNLLLIQDEPRSVRNIKKLIKELDKPIEQIAIEA
RIVTINDESLKELGVRWGIFSPTDNAHRIGGSLAGNGFDNLVNQLNVNFP
TTTTPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSA
SIKQGTELPYILVNEKSGSQSVEFREAVLGLEVTPHISQDKQILLDLIVS
QNSPGSRVAYGLGEVVSIDKQEINTQVFAKDGETIVLGGVFSDTITKGTD
KVPVLGDIPGIKHLFSKESERHQKRELVIFVTPHILRKGETPDAFKQKRI
GVNEQIMAKGENKKDLNRK

Gene Nucleotide Sequence:  Sequence Viewer
ATGAAATCGATCCTTTCCCGACGACTAAAGTGCGGTCTGTTTTTCGGGTG
TTTTTTAAGTCTTGCGGTGCAGGCGGAACAAAATCCGGTGTTTTCCATTC
GGCTGAAACAGGCACCACTGGTTCCGACTTTGCAGCAGTTGGCATTAGCC
CACAATACCAATTTGATTATTGACGATGAACTGCAAGGCACGGTGTCGTT
ACAGTTGGAAAACGTGGATTTGGATCAGCTGTTTCGTTCTGTGGCAAAAA
TTAAACAACTGGATTTATGGCAGGAAAACGGCATTTATTATTTCACTAAA
GGCGACACCAACACGAAATTTGCCGGCAAAATGGAAGAGCCTTTCCCTCT
TTCTCTGCCCATGGCGGAAGAACCGGCACAGCTGAACACGGCGACCATTA
AATTACACTTTGCCAAAGCGTCGGAAGTGATGAAATCCCTCACCGGGGGG
AGTGGTTCCCTGTTGTCGCCTAACGGCAGTATCACTTTCGACGATCGTAG
CAATTTGTTGCTGATTCAGGATGAACCGCGCTCCGTCCGCAACATAAAAA
AGCTGATTAAGGAACTGGATAAACCCATTGAGCAAATCGCCATTGAAGCG
CGCATTGTCACCATTAACGATGAAAGCCTGAAAGAACTGGGCGTGCGCTG
GGGCATTTTCAGCCCGACGGACAACGCCCATCGTATCGGTGGCAGTTTGG
CGGGCAACGGCTTTGATAACCTTGTCAATCAGTTAAACGTAAATTTTCCC
ACGACCACGACACCGGCAGGCTCTGTGGCGTTACAGGTTGCGAAAATCAA
CGGGCGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAATAATG
TGGAAATCATCGCAAGCCCACGCCTGCTAACGACAAACAAAAAAAGCGCC
AGCATCAAACAGGGGACGGAATTGCCCTATATTCTGGTGAACGAAAAAAG
CGGTTCGCAAAGCGTGGAATTTCGTGAGGCGGTACTAGGTTTGGAAGTCA
CGCCGCACATTTCGCAGGATAAACAAATTCTGTTAGATCTTATCGTCAGC
CAAAACTCGCCGGGCAGCCGTGTGGCGTACGGTTTGGGCGAAGTGGTTTC
TATTGATAAACAGGAGATTAATACACAAGTCTTCGCCAAGGACGGCGAAA
CCATTGTGCTGGGCGGTGTATTTAGCGATACCATCACCAAAGGCACCGAT
AAAGTGCCGGTGCTGGGTGACATTCCGGGTATTAAACATTTATTCAGCAA
GGAAAGTGAACGCCATCAAAAACGCGAGCTGGTGATTTTTGTCACACCAC
ATATTTTGCGTAAAGGCGAAACCCCGGACGCTTTCAAACAAAAGCGAATC
GGGGTAAATGAGCAAATCATGGCAAAAGGGGAGAATAAAAAGGACCTAAA
TAGGAAA

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