R = Retrieve links to Related sequences (neighbors).
Use the 
icon (if present) to retrieve links to the Sequence Retrieval System (SRS).
Use the 
icon (if present) to retrieve links to the Ligand Enzyme and Chemical Compound Database .
Use the 
icon (if present) to retrieve links to the Protein Data Bank database.
WARNING: Descriptions of 187 database sequences were not reported due to the
limiting value of parameter V = 50.
>gi|4062934|dbj|BAA36181.1| (D88272) formate dehydrogenase [Hordeum vulgare]
Length = 377
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | 377
0 150 300
Plus Strand HSPs:
Score = 939 (330.5 bits), Expect = 2.3e-93, P = 2.3e-93
Identities = 173/198 (87%), Positives = 190/198 (95%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
VAGIAHRAYDLEGKTVGTVGAGR G+LLLQRLKPFNCNLLY+DRL++N +LEKEIGAKFE
Sbjct: 178 VAGIAHRAYDLEGKTVGTVGAGRYGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 237
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
EDLDAMLPKCDVVVIN PLTE+TRG+F+K +IAK KKGV+IVNNARGAIMDTQA+ADACS
Sbjct: 238 EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACS 297
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SGH+AGYGGDVW QP+PKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDR+FKG
Sbjct: 298 SGHIAGYGGDVWFPQPAPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYFKG 357
Query: 552 EDFPEQNYIVKEGQLASQ 605
E+FP +NYIVKEG+LASQ
Sbjct: 358 EEFPVENYIVKEGELASQ 375
>gi|4760553|dbj|BAA77337.1| (AB019533) Nad-dependent formate dehydrogenase
[Oryza sativa]
Length = 376
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | 376
0 150 300
Plus Strand HSPs:
Score = 919 (323.5 bits), Expect = 3.1e-91, P = 3.1e-91
Identities = 172/198 (86%), Positives = 188/198 (94%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
VAGIA+RAYDLEGKTVGTVGAGRIG+LLLQRLKPFNCNLLY+DRL+++ +LEKEIGAK+E
Sbjct: 177 VAGIAYRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLKIDPELEKEIGAKYE 236
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
EDLDAMLPKCDV+VIN PLTE+TRG+F+K RIAK KKGV+IVNNARGAIMDTQA+ADACS
Sbjct: 237 EDLDAMLPKCDVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQAVADACS 296
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SG VAGYGGDVW QP+PK PWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDR+FKG
Sbjct: 297 SGQVAGYGGDVWFPQPAPKGPPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRYFKG 356
Query: 552 EDFPEQNYIVKEGQLASQ 605
EDFP QNYIVKEGQLASQ
Sbjct: 357 EDFPVQNYIVKEGQLASQ 374
>gi|729470|sp|Q07511|FDH_SOLTU MITOCHONDRIAL FORMATE DEHYDROGENASE PRECURSOR
(NAD-DEPENDENT FORMATE DEHYDROGENASE) (FDH) >gi|542089|pir||JQ2272
formate dehydrogenase (EC 1.2.1.2) precursor, mitochondrial -
potato
Length = 379
Frame 3 hits (HSPs): ___________________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 379
0 150 300
__________________
Annotated Domains:
DOMO DM00386: D-ISOMERSPECIFIC2-HYDROXYACIDDE 58..366
Entrez np-binding site: NAD (ADP PART) (BY SIMI 193..227
Entrez active site: SUBSTRATE-BINDING (BY SIMIL 285
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 124..333
PRODOM PD088087: FDH_SOLTU 1..34
PRODOM PD150030: FDH(5) 36..122
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 124..332
PRODOM PD165943: FDH(1) Q9ZRI8(1) 334..378
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 187..194
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 195..222
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 274..290
__________________
Plus Strand HSPs:
Score = 894 (314.7 bits), Expect = 1.4e-88, P = 1.4e-88
Identities = 163/198 (82%), Positives = 183/198 (92%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
VA IAHRAYDLEGKTVGTVGAGRIG+LLLQRLKPFNCNLLY+DRL+M+++LE +IGAKFE
Sbjct: 180 VAAIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLKMDSELENQIGAKFE 239
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
EDLD ML KCD+VVIN PLTE+T+G+FDK RIAK KKGV+IVNNARGAIMDTQA+ DAC+
Sbjct: 240 EDLDKMLSKCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVDACN 299
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SGH+AGY GDVW QP+PKDHPWRYMPN AMTPHISGTTIDAQLRYAAG KDMLDR+FKG
Sbjct: 300 SGHIAGYSGDVWYPQPAPKDHPWRYMPNQAMTPHISGTTIDAQLRYAAGTKDMLDRYFKG 359
Query: 552 EDFPEQNYIVKEGQLASQ 605
EDFP +NYIVK+G+LA Q
Sbjct: 360 EDFPAENYIVKDGELAPQ 377
>gi|11991527|emb|CAA79702.2| (Z21493) mitochondrial formate dehydrogenase
precursor [Solanum tuberosum]
Length = 381
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | 381
0 150 300
Plus Strand HSPs:
Score = 894 (314.7 bits), Expect = 1.4e-88, P = 1.4e-88
Identities = 163/198 (82%), Positives = 183/198 (92%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
VA IAHRAYDLEGKTVGTVGAGRIG+LLLQRLKPFNCNLLY+DRL+M+++LE +IGAKFE
Sbjct: 182 VAAIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLKMDSELENQIGAKFE 241
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
EDLD ML KCD+VVIN PLTE+T+G+FDK RIAK KKGV+IVNNARGAIMDTQA+ DAC+
Sbjct: 242 EDLDKMLSKCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVDACN 301
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SGH+AGY GDVW QP+PKDHPWRYMPN AMTPHISGTTIDAQLRYAAG KDMLDR+FKG
Sbjct: 302 SGHIAGYSGDVWYPQPAPKDHPWRYMPNQAMTPHISGTTIDAQLRYAAGTKDMLDRYFKG 361
Query: 552 EDFPEQNYIVKEGQLASQ 605
EDFP +NYIVK+G+LA Q
Sbjct: 362 EDFPAENYIVKDGELAPQ 379
>gi|11357294|pir||T51423 formate dehydrogenase (FDH) - Arabidopsis thaliana
>gi|6625953|gb|AAF19435.1|AF208028_1 (AF208028) NAD-dependent
formate dehydrogenase 1A [Arabidopsis thaliana]
>gi|6625955|gb|AAF19436.1|AF208029_1 (AF208029) NAD-dependent
formate dehydrogenase 1B [Arabidopsis thaliana]
>gi|6681408|dbj|BAA88683.1| (AB023897) formate dehydrogenase
[Arabidopsis thaliana] >gi|7677266|gb|AAF67100.1|AF217195_1
(AF217195) formate dehydrogenase [Arabidopsis thaliana]
>gi|9755746|emb|CAC01877.1| (AL391149) formate dehydrogenase (FDH)
[Arabidopsis thaliana]
Length = 384
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | 384
0 150 300
Plus Strand HSPs:
Score = 844 (297.1 bits), Expect = 2.7e-83, P = 2.7e-83
Identities = 155/198 (78%), Positives = 175/198 (88%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
VAGIA+RAYDLEGKT+GTVGAGRIGKLLLQRLKPF CNLLY+DRL+M +LEKE GAKF
Sbjct: 185 VAGIAYRAYDLEGKTIGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKFV 244
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
EDL+ MLPKCDV+VINMPLTE+TRG+F+K I K KKGV+IVNNARGAIM+ QA+ DA
Sbjct: 245 EDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVE 304
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SGH+ GY GDVW QP+PKDHPWRYMPN AMTPH SGTTIDAQLRYAAG KDML+R+FKG
Sbjct: 305 SGHIGGYSGDVWDPQPAPKDHPWRYMPNQAMTPHTSGTTIDAQLRYAAGTKDMLERYFKG 364
Query: 552 EDFPEQNYIVKEGQLASQ 605
EDFP +NYIVK+G+LA Q
Sbjct: 365 EDFPTENYIVKDGELAPQ 382
>gi|729469|sp|Q07103|FDH_NEUCR FORMATE DEHYDROGENASE (NAD-DEPENDENT FORMATE
DEHYDROGENASE) (FDH) >gi|539386|pir||A47117 formate dehydrogenase
(EC 1.2.1.2) - Neurospora crassa >gi|1321604|gb|AAA99900.1|
(L13964) formate dehydrogenase [Neurospora crassa]
>gi|11595632|emb|CAC18252.1| (AL451018) formate dehydrogenase
[Neurospora crassa]
Length = 375
Frame 3 hits (HSPs): ____________________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 375
0 150 300
__________________
Annotated Domains:
Entrez np-binding site: NAD (ADP PART) (BY SIMI 166..201
Entrez active site: SUBSTRATE-BINDING (BY SIMIL 259
Entrez Domain: ALA-RICH. 364..374
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 95..312
PRODOM PD150030: FDH(5) 7..93
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 95..293
PRODOM PD033449: FDH(4) 314..359
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 168..196
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 218..231
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 248..264
__________________
Plus Strand HSPs:
Score = 521 (183.4 bits), Expect = 4.6e-49, P = 4.6e-49
Identities = 106/205 (51%), Positives = 143/205 (69%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKF 188
VA A +DLEGK VGTVG GRIG+ +L+RLKPF+C LLYYD ++ + E EIG +
Sbjct: 153 VAEAAKNEFDLEGKVVGTVGVGRIGERVLRRLKPFDCKELLYYDYQPLSAEKEAEIGCRR 212
Query: 189 EEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADAC 368
DL+ ML +CDVV IN PL E+T+GLF+K I+K KKG +VN ARGAI+ + +A+A
Sbjct: 213 VADLEEMLAQCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNTARGAIVVKEDVAEAL 272
Query: 369 SSGHVAGYGGDVWPIQPSPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDML 533
SGH+ GYGGDVW QP+P+DHP RY N +AM PH+SGT++DAQ RYAAG K ++
Sbjct: 273 KSGHLRGYGGDVWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTSLDAQKRYAAGTKAII 332
Query: 534 DRHFKGE-DFPEQNYIVKEGQLASQ 605
+ + G+ D+ ++ IV G A++
Sbjct: 333 ESYLSGKHDYRPEDLIVYGGDYATK 357
>gi|416574|sp|Q03134|FDH_EMENI PROBABLE FORMATE DEHYDROGENASE (NAD-DEPENDENT
FORMATE DEHYDROGENASE) (FDH) >gi|419908|pir||S30088 aciA protein -
Emericella nidulans >gi|5545|emb|CAA77687.1| (Z11612) AciA
[Emericella nidulans] >gi|384296|prf||1905380A aciA gene
[Emericella nidulans]
Length = 377
Frame 3 hits (HSPs): ______________ _______________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 377
0 150 300
__________________
Annotated Domains:
DOMO DM00386: D-ISOMERSPECIFIC2-HYDROXYACIDDE 24..356
Entrez np-binding site: NAD (ADP PART) (BY SIMI 161..191
Entrez active site: SUBSTRATE-BINDING (BY SIMIL 271
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 90..246
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 262..324
PRODOM PD150030: FDH(5) 1..88
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 90..305
PRODOM PD033449: FDH(4) 326..372
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 163..191
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 213..226
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 260..276
__________________
Plus Strand HSPs:
Score = 276 (97.2 bits), Expect = 3.3e-48, Sum P(2) = 3.3e-48
Identities = 55/99 (55%), Positives = 72/99 (72%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKF 188
VA +A +DLE K VGTVG GRIG+ +L+RLKPF+C LLYYD + ++EKEIGA+
Sbjct: 148 VAAVAKNEFDLENKVVGTVGVGRIGERVLRRLKPFDCKELLYYDYQPLRPEVEKEIGARR 207
Query: 189 EEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKG 305
+ L+ M+ +CDVV IN PL E+TRGLF+K I+K K G
Sbjct: 208 VDSLEEMVSQCDVVTINCPLHEKTRGLFNKELISKMKPG 246
Score = 254 (89.4 bits), Expect = 3.3e-48, Sum P(2) = 3.3e-48
Identities = 52/108 (48%), Positives = 72/108 (66%), Frame = +3
Query: 300 KGVVIVNNARGAIMDTQAIADACSSGHVAGYGGDVWPIQPSPKDHPWRYMPN-----HAM 464
KG +VN ARGAI+ + +A+A SGH+ GYGGDVW QP+PK+HP RY + +A
Sbjct: 262 KGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDVWFPQPAPKEHPLRYAEHPWGGGNAT 321
Query: 465 TPHISGTTIDAQLRYAAGVKDMLDRHFKGE-DFPEQNYIVKEGQLASQ 605
PH+SGT++ AQ+RYA G K +LD +F G D+ Q+ IV G A++
Sbjct: 322 VPHMSGTSLAAQIRYANGTKAILDSYFSGRFDYQPQDLIVHGGDYATK 369
>gi|4572458|gb|AAD23831.1|AF123482_1 (AF123482) NAD-dependent formate
dehydrogenase [Mycosphaerella graminicola]
Length = 417
Frame 3 hits (HSPs): __________________________
__________________________________________________
Database sequence: | | | | 417
0 150 300
Plus Strand HSPs:
Score = 512 (180.2 bits), Expect = 4.2e-48, P = 4.2e-48
Identities = 107/206 (51%), Positives = 141/206 (68%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKF 188
VA +A YDLEGK VGTV GRIG+ +L+RLKPF+C LLY+D + ++EKEIG +
Sbjct: 201 VAAVAKNEYDLEGKVVGTVAVGRIGERVLRRLKPFDCKELLYFDYQALAPEVEKEIGCRR 260
Query: 189 EEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADAC 368
+ L+ ML +CDVV IN PL E+TRGLF+K I+K KKG +VN ARGAI+ + +A A
Sbjct: 261 VDTLEEMLAQCDVVTINCPLHEKTRGLFNKELISKMKKGSWLVNTARGAIVVKEEVAAAL 320
Query: 369 SSGHVAGYGGDVWPIQPSPKDHPWR---YMP---NHAMTPHISGTTIDAQLRYAAGVKDM 530
G + GYGGDVW +P P DHP+R Y +AM PH+SGT+IDAQ RYAAG K +
Sbjct: 321 KFGQLRGYGGDVWFPKPVPADHPFRTASYSTWGGGNAMVPHMSGTSIDAQARYAAGTKAI 380
Query: 531 LDRHFKG-EDFPEQNYIVKEGQLASQ 605
LD +F G ED+ ++ IV +G A++
Sbjct: 381 LDSYFSGREDYRPEDLIVHKGDYATK 406
>gi|7657869|emb|CAA09466.2| (AJ011046) formate dehydrogenase [Candida boidinii]
Length = 364
Frame 3 hits (HSPs): _____________________________
__________________________________________________
Database sequence: | | | | 364
0 150 300
Plus Strand HSPs:
Score = 497 (175.0 bits), Expect = 1.6e-46, P = 1.6e-46
Identities = 100/205 (48%), Positives = 139/205 (67%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKF 188
VA IA AYD+EGKT+ T+GAGRIG +L+RL PFN LLYYD + D E+++GA+
Sbjct: 152 VAAIAKDAYDIEGKTIATIGAGRIGYRVLERLVPFNPKELLYYDYQALPKDAEEKVGARR 211
Query: 189 EEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADAC 368
E+++ ++ + D+V +N PL T+GL +K ++K KKG +VN ARGAI + +A A
Sbjct: 212 VENIEELVAQADIVTVNAPLHAGTKGLINKELLSKFKKGAWLVNTARGAICVAEDVAAAL 271
Query: 369 SSGHVAGYGGDVWPIQPSPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDML 533
SG + GYGGDVW QP+PKDHPWR M N +AMTPH SGTT+DAQ RYA G K++L
Sbjct: 272 ESGQLRGYGGDVWFPQPAPKDHPWRDMRNKYGAGNAMTPHYSGTTLDAQTRYAQGTKNIL 331
Query: 534 DRHFKGE-DFPEQNYIVKEGQLASQ 605
+ F G+ D+ Q+ I+ G+ ++
Sbjct: 332 ESFFTGKFDYRPQDIILLNGEYVTK 356
>gi|1364111|pir||JC4252 formate dehydrogenase (EC 1.2.1.2) - yeast (Candida
methylica) >gi|1181204|emb|CAA57036.1| (X81129) NAD-dependent
formate dehydrogenase [Candida methylica]
Length = 364
Frame 3 hits (HSPs): _____________________________
Annotated Domains: ______ ___ ___
__________________________________________________
Database sequence: | | | | 364
0 150 300
__________________
Annotated Domains:
Entrez region: beta-alpha-beta NAD nucleotide-b 165..195
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 159..166
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 167..195
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 217..230
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 247..263
__________________
Plus Strand HSPs:
Score = 493 (173.5 bits), Expect = 4.3e-46, P = 4.3e-46
Identities = 99/205 (48%), Positives = 139/205 (67%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKF 188
VA IA AYD+EGKT+ T+GAGRIG +L+RL PFN LLYYD + + E+++GA+
Sbjct: 152 VAAIAKDAYDIEGKTIATIGAGRIGYRVLERLLPFNPKELLYYDYQALPKEAEEKVGARR 211
Query: 189 EEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADAC 368
E+++ ++ + D+V +N PL T+GL +K ++K KKG +VN ARGAI + +A A
Sbjct: 212 VENIEELVAQADIVTVNAPLHAGTKGLINKELLSKFKKGAWLVNTARGAICVAEDVAAAL 271
Query: 369 SSGHVAGYGGDVWPIQPSPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDML 533
SG + GYGGDVW QP+PKDHPWR M N +AMTPH SGTT+DAQ RYA G K++L
Sbjct: 272 ESGQLRGYGGDVWFPQPAPKDHPWRDMRNKYGAGNAMTPHYSGTTLDAQTRYAEGTKNIL 331
Query: 534 DRHFKGE-DFPEQNYIVKEGQLASQ 605
+ F G+ D+ Q+ I+ G+ ++
Sbjct: 332 ESFFTGKFDYRPQDIILLNGEYVTK 356
>gi|2276465|gb|AAC49766.1| (AF004096) NAD-dependent formate dehydrogenase
[Candida boidinii] >gi|5824352|emb|CAB54834.1| (AJ245934) formate
dehydrogenase [Candida boidinii]
Length = 364
Frame 3 hits (HSPs): _____________________________
__________________________________________________
Database sequence: | | | | 364
0 150 300
Plus Strand HSPs:
Score = 493 (173.5 bits), Expect = 4.3e-46, P = 4.3e-46
Identities = 99/205 (48%), Positives = 139/205 (67%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKF 188
VA IA AYD+EGKT+ T+GAGRIG +L+RL PFN LLYYD + + E+++GA+
Sbjct: 152 VAAIAKDAYDIEGKTIATIGAGRIGYRVLERLLPFNPKELLYYDYQALPKEAEEKVGARR 211
Query: 189 EEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADAC 368
E+++ ++ + D+V +N PL T+GL +K ++K KKG +VN ARGAI + +A A
Sbjct: 212 VENIEELVAQADIVTVNAPLHAGTKGLINKELLSKFKKGAWLVNTARGAICVAEDVAAAL 271
Query: 369 SSGHVAGYGGDVWPIQPSPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDML 533
SG + GYGGDVW QP+PKDHPWR M N +AMTPH SGTT+DAQ RYA G K++L
Sbjct: 272 ESGQLRGYGGDVWFPQPAPKDHPWRDMRNKYGAGNAMTPHYSGTTLDAQTRYAEGTKNIL 331
Query: 534 DRHFKGE-DFPEQNYIVKEGQLASQ 605
+ F G+ D+ Q+ I+ G+ ++
Sbjct: 332 ESFFTGKFDYRPQDIILLNGEYVTK 356
>gi|9971908|gb|AAG10470.1|AF279106_32 (AF279106) predicted NAD-dependent
formate dehydrogenase [uncultured proteobacterium EBAC31A08]
Length = 398
Frame 3 hits (HSPs): _________________________
__________________________________________________
Database sequence: | | | | 398
0 150 300
Plus Strand HSPs:
Score = 493 (173.5 bits), Expect = 4.3e-46, P = 4.3e-46
Identities = 92/196 (46%), Positives = 132/196 (67%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
+A R+YD+EG VGTV AGRIG +L+++KPF+ +L Y+D +++ ++E E+ +
Sbjct: 179 IADAVQRSYDVEGMHVGTVAAGRIGIDMLRKMKPFDVHLHYFDIHKLSDEIEAELNLTYH 238
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
+ +++++ CDVV I+ PL +T LFD I+K K+G I+N ARG I D AIA
Sbjct: 239 DSVESLVAVCDVVNISCPLHPKTEHLFDDEMISKMKRGAYIINTARGKICDKDAIARGLE 298
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SG ++GY GDVW QP+P DH WR MPNH MTPH SGT++ AQ RYAAGV+++L+ +F G
Sbjct: 299 SGQLSGYAGDVWFPQPAPNDHVWRTMPNHGMTPHTSGTSLSAQTRYAAGVREILECYFAG 358
Query: 552 EDFPEQNYIVKEGQLA 599
E + IV+ G LA
Sbjct: 359 EPIRDPYLIVQNGDLA 374
>gi|999847|pdb|2NAD|A Chain A, Nad-Dependent Formate Dehydrogenase
(E.C.1.2.1.2) (Holo Form) Complexed With Nad And Azide
>gi|999848|pdb|2NAD|B Chain B, Nad-Dependent Formate Dehydrogenase
(E.C.1.2.1.2) (Holo Form) Complexed With Nad And Azide
>gi|999845|pdb|2NAC|A Chain A, Nad-Dependent Formate Dehydrogenase
(E.C.1.2.1.2) (Apo Form) >gi|999846|pdb|2NAC|B Chain B,
Nad-Dependent Formate Dehydrogenase (E.C.1.2.1.2) (Apo Form)
Length = 393
Frame 3 hits (HSPs): __________________________
__________________________________________________
Database sequence: | | | | 393
0 150 300
Plus Strand HSPs:
Score = 476 (167.6 bits), Expect = 2.7e-44, P = 2.7e-44
Identities = 94/196 (47%), Positives = 124/196 (63%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
+A AYDLE VGTV AGRIG +L+RL PF+ +L Y DR R+ +EKE+ +
Sbjct: 179 IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELNLTWH 238
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
+ M P CDVV +N PL +T + + + K+G IVN ARG + D A+A A
Sbjct: 239 ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALE 298
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SG +AGY GDVW QP+PKDHPWR MP + MTPHISGTT+ AQ RYAAG +++L+ F+G
Sbjct: 299 SGRLAGYAGDVWFPQPAPKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTREILECFFEG 358
Query: 552 EDFPEQNYIVKEGQLA 599
++ IV+ G LA
Sbjct: 359 RPIRDEYLIVQGGALA 374
>gi|1477947|gb|AAB36206.1| NAD(+)-dependent formate dehydrogenase, McFDH {EC
1.2.1.2} [Mycobacterium vaccae, N10, Peptide, 400 aa]
Length = 400
Frame 3 hits (HSPs): _________________________
Annotated Domains: ____ __ ___
__________________________________________________
Database sequence: | | | | 400
0 150 300
__________________
Annotated Domains:
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 194..221
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 243..256
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 273..289
__________________
Plus Strand HSPs:
Score = 476 (167.6 bits), Expect = 2.7e-44, P = 2.7e-44
Identities = 94/196 (47%), Positives = 124/196 (63%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
+A AYDLE VGTV AGRIG +L+RL PF+ +L Y DR R+ +EKE+ +
Sbjct: 179 IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELNLTWH 238
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
+ M P CDVV +N PL +T + + + K+G IVN ARG + D A+A A
Sbjct: 239 ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALE 298
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SG +AGY GDVW QP+PKDHPWR MP + MTPHISGTT+ AQ RYAAG +++L+ F+G
Sbjct: 299 SGRLAGYAGDVWFPQPAPKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTREILECFFEG 358
Query: 552 EDFPEQNYIVKEGQLA 599
++ IV+ G LA
Sbjct: 359 RPIRDEYLIVQGGALA 374
>gi|4033692|sp|P33160|FDH_PSESR FORMATE DEHYDROGENASE (NAD-DEPENDENT FORMATE
DEHYDROGENASE) (FDH)
Length = 401
Frame 3 hits (HSPs): _________________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 401
0 150 300
__________________
Annotated Domains:
DOMO DM00386: D-ISOMERSPECIFIC2-HYDROXYACIDDE 57..365
Entrez Domain: CATALYTIC. 2..147
Entrez Domain: COENZYME-BINDING. 148..334
Entrez Domain: CATALYTIC. 335..401
Entrez np-binding site: NAD (ADP PART). 193..227
Entrez active site: POTENTIAL. 6
Entrez active site: SUBSTRATE-BINDING. 285
Entrez mutagenized site: C->S,M: HIGH RESISTANC 256
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 123..332
PRODOM PD033443: FDH(1) O08375(1) 1..46
PRODOM PD150030: FDH(5) 49..121
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 123..331
PRODOM PD033449: FDH(4) 334..373
PRODOM PD033450: FDH(1) O08375(1) 375..397
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 195..222
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 244..257
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 274..290
__________________
Plus Strand HSPs:
Score = 476 (167.6 bits), Expect = 2.7e-44, P = 2.7e-44
Identities = 94/196 (47%), Positives = 124/196 (63%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
+A AYDLE VGTV AGRIG +L+RL PF+ +L Y DR R+ +EKE+ +
Sbjct: 180 IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELNLTWH 239
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
+ M P CDVV +N PL +T + + + K+G IVN ARG + D A+A A
Sbjct: 240 ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALE 299
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SG +AGY GDVW QP+PKDHPWR MP + MTPHISGTT+ AQ RYAAG +++L+ F+G
Sbjct: 300 SGRLAGYAGDVWFPQPAPKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTREILECFFEG 359
Query: 552 EDFPEQNYIVKEGQLA 599
++ IV+ G LA
Sbjct: 360 RPIRDEYLIVQGGALA 375
>gi|94970|pir||JU0334 formate dehydrogenase (EC 1.2.1.2) - Pseudomonas sp
Length = 393
Frame 3 hits (HSPs): __________________________
Annotated Domains: ____ ___ ___
__________________________________________________
Database sequence: | | | | 393
0 150 300
__________________
Annotated Domains:
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 194..221
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 243..256
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 273..289
__________________
Plus Strand HSPs:
Score = 468 (164.7 bits), Expect = 1.9e-43, P = 1.9e-43
Identities = 94/196 (47%), Positives = 122/196 (62%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
+A AYDLE VGTV AGRIG +L+RL PF+ L Y DR R+ +EKE+ +
Sbjct: 179 IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDHVLHYTDRHRLPESVEKELNLTWH 238
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
+ M P CDVV +N PL +T + + + K+G IVN ARG + D A+A A
Sbjct: 239 ATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALE 298
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SG +AGY GDVW QP+PKDHPWR MP MTPHISGTT+ AQ RYAAG +++L+ F+G
Sbjct: 299 SGRLAGYAGDVWFPQPAPKDHPWRTMPYDGMTPHISGTTLTAQARYAAGTREILECFFEG 358
Query: 552 EDFPEQNYIVKEGQLA 599
++ IV+ G LA
Sbjct: 359 RPIRDEYLIVQGGALA 374
>gi|2113888|emb|CAA73696.1| (Y13245) NAD-dependent formate dehydrogenase
[Moraxella sp.]
Length = 402
Frame 3 hits (HSPs): _________________________
__________________________________________________
Database sequence: | | | | 402
0 150 300
Plus Strand HSPs:
Score = 454 (159.8 bits), Expect = 5.8e-42, P = 5.8e-42
Identities = 89/196 (45%), Positives = 124/196 (63%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFE 191
+A R+YD+EG VGTV AGRIG +L+ L PF+ +L Y DR R+ +EKE+ +
Sbjct: 180 IADCVARSYDVEGMHVGTVAAGRIGLRVLRLLAPFDMHLHYTDRHRLPEAVEKELNLTWH 239
Query: 192 EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACS 371
+ M CDVV +N PL +T + + + K+G +VN ARG + D AI A
Sbjct: 240 ATREDMYGACDVVTLNCPLHPETEHMINDETLKLFKRGAYLVNTARGKLCDRDAIVRALE 299
Query: 372 SGHVAGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
SG +AGY GDVW QP+P DHPWR MP++ MTPHISGT++ AQ RYAAG +++L+ +F+G
Sbjct: 300 SGRLAGYAGDVWFPQPAPNDHPWRTMPHNGMTPHISGTSLSAQTRYAAGTREILECYFEG 359
Query: 552 EDFPEQNYIVKEGQLA 599
++ IV+ G LA
Sbjct: 360 RPIRDEYLIVQGGGLA 375
>gi|6324964 ref|NP_015033.1| similar to formate dehydrogenases; Fdh1p
[Saccharomyces cerevisiae] >gi|2117510|pir||S67300 probable
membrane protein YOR388c - yeast (Saccharomyces cerevisiae)
>gi|1420835|emb|CAA99720.1| (Z75296) ORF YOR388c [Saccharomyces
cerevisiae]
Length = 376
Frame 3 hits (HSPs): ______________________________
__________________________________________________
Database sequence: | | | | 376
0 150 300
Plus Strand HSPs:
Score = 446 (157.0 bits), Expect = 4.1e-41, P = 4.1e-41
Identities = 105/217 (48%), Positives = 138/217 (63%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYD--RL------RMNTDL 164
+AG+A YDLE K + TVGAGRIG +L+RL FN LLYYD L R+N +
Sbjct: 154 IAGVAKNEYDLEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYDYQELPAEAINRLN-EA 212
Query: 165 EKEIGAKFE-----EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNAR 329
K + + E L+ M+ + DVV IN PL + +RGLF+K I+ K G +VN AR
Sbjct: 213 SKLFNGRGDIVQRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTAR 272
Query: 330 GAIMDTQAIADACSSGHVAGYGGDVWPIQPSPKDHPWRYMPN--H---AMTPHISGTTID 494
GAI + +A+A SG +AGYGGDVW QP+PKDHPWR M N H AMT HISGT++D
Sbjct: 273 GAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPKDHPWRTMDNKDHVGNAMTVHISGTSLD 332
Query: 495 AQLRYAAGVKDMLDRHF-KGEDFPEQNYIVKEGQLASQ 605
AQ RYA GVK++L+ +F K D+ Q+ IV+ G A++
Sbjct: 333 AQKRYAQGVKNILNSYFSKKFDYRPQDIIVQNGSYATR 370
>gi|462075|sp|P33677|FDH_PICAN FORMATE DEHYDROGENASE (NAD-DEPENDENT FORMATE
DEHYDROGENASE) (FDH)
Length = 362
Frame 3 hits (HSPs): _____________________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 362
0 150 300
__________________
Annotated Domains:
DOMO DM00386: D-ISOMERSPECIFIC2-HYDROXYACIDDE 26..342
Entrez np-binding site: NAD (ADP PART) (BY SIMI 165..200
Entrez active site: SUBSTRATE-BINDING (BY SIMIL 258
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 93..310
PRODOM PD150030: FDH(5) 4..91
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 93..309
PRODOM PD033449: FDH(4) 311..357
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 167..195
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 217..230
PROSITE D_2_HYDROXYACID_DH_3: D-isomer specific 247..263
__________________
Plus Strand HSPs:
Score = 440 (154.9 bits), Expect = 1.8e-40, P = 1.8e-40
Identities = 91/201 (45%), Positives = 130/201 (64%), Frame = +3
Query: 12 VAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKF 188
VA IA ++D+EGK + T+GAGRIG +L+RL FN LLYYD ++ + E+++GA+
Sbjct: 152 VAEIAKDSFDIEGKVIATIGAGRIGYRVLERLVAFNPKELLYYDYQSLSKEAEEKVGARR 211
Query: 189 EEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADAC 368
D+ ++ + D+V IN PL ++GL + + KKG +VN ARGAI + +A A
Sbjct: 212 VHDIKELVAQADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVNTARGAICVAEDVAAAV 271
Query: 369 SSGHVAGYGGDVWPIQPSPKDHPWRYMPN-----HAMTPHISGTTIDAQLRYAAGVKDML 533
SG + GYGGDVW QP+PKDHPWR M N +AMTPH SG+ IDAQ+RYA G K++L
Sbjct: 272 KSGQLRGYGGDVWFPQPAPKDHPWRSMANKYGAGNAMTPHYSGSVIDAQVRYAQGTKNIL 331
Query: 534 DRHFKGE-DFPEQNYIVKEGQ 593
+ F + D+ Q+ I+ G+
Sbjct: 332 ESFFTQKFDYRPQDIILLNGK 352
>gi|6324980 ref|NP_015048.1| Ypl275wp [Saccharomyces cerevisiae]
>gi|2117511|pir||S65308 hypothetical protein YPL275w - yeast
(Saccharomyces cerevisiae) >gi|1370568|emb|CAA98013.1| (Z73632) ORF
YPL275w [Saccharomyces cerevisiae]
Length = 236
Frame 3 hits (HSPs): _____________________________________________
__________________________________________________
Database sequence: | | | | | | 236
0 50 100 150 200
Plus Strand HSPs:
Score = 421 (148.2 bits), Expect = 1.8e-38, P = 1.8e-38
Identities = 101/209 (48%), Positives = 132/209 (63%), Frame = +3
Query: 36 YDLEGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYD--RL------RMNTDLEKEIGAKF 188
YDLE K + TVGAGRIG +L+RL FN LLYYD L R+N + K +
Sbjct: 22 YDLEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYDYQELPAEAINRLN-EASKLFNGRG 80
Query: 189 E-----EDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQA 353
+ E L+ M+ + DVV IN PL + +RGLF+K I+ K G +VN ARGAI +
Sbjct: 81 DIVQRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAED 140
Query: 354 IADACSSGHVAGYGGDVWPIQPSPKDHPWRYMPN--H---AMTPHISGTTIDAQLRYAAG 518
+A+A SG +AGYGGDVW QP+PKDHPWR M N H AMT HISGT++ AQ RYA G
Sbjct: 141 VAEAVKSGKLAGYGGDVWDKQPAPKDHPWRTMDNKDHVGNAMTVHISGTSLHAQKRYAQG 200
Query: 519 VKDMLDRHF-KGEDFPEQNYIVKEGQLASQ 605
VK++L+ +F K D+ Q+ IV+ G A++
Sbjct: 201 VKNILNSYFSKKFDYRPQDIIVQNGSYATR 230
>gi|7431352|pir||B75120 phosphoglycerate dehydrogenase truncated homolog
PAB0514 [imported] - Pyrococcus abyssi (strain Orsay)
>gi|5458186|emb|CAB49675.1| (AJ248285) phosphoglycerate
dehydrogenase (serA), Nter fragment [Pyrococcus abyssi]
Length = 307
Frame 3 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | | | | | 307
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 330 (116.2 bits), Expect = 8.0e-29, P = 8.0e-29
Identities = 68/171 (39%), Positives = 102/171 (59%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
+LEGKT+G +G GRIG + + + NLL YD N + KE+G KF DL+ +L +
Sbjct: 139 ELEGKTLGIIGFGRIGYQVAKIARALGMNLLLYDPYP-NEERAKEVGGKFV-DLETLLRE 196
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
D+V I++PL E T L ++ R+ KK +++N +RGA++DT A+ A G +AG G
Sbjct: 197 SDIVTIHVPLLESTYHLINEERLKLMKKSAILINTSRGAVVDTNALVKALEEGWIAGAGL 256
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
DV+ +P PKDHP N +TPHI +T++AQ R V + + + KG
Sbjct: 257 DVYEEEPLPKDHPLTKFDNVVLTPHIGASTVEAQERAGVEVAEKVVKILKG 307
>gi|7431362|pir||E71011 probable phosphoglycerate dehydrogenase - Pyrococcus
horikoshii >gi|3257810|dbj|BAA30493.1| (AP000006) 307aa long
hypothetical phosphoglycerate dehydrogenase [Pyrococcus horikoshii]
Length = 307
Frame 3 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | | | | | 307
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 317 (111.6 bits), Expect = 1.9e-27, P = 1.9e-27
Identities = 66/171 (38%), Positives = 99/171 (57%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
+LEGKT+G +G GRIG + + N+L YD N + KE+ KF DL+ +L +
Sbjct: 139 ELEGKTIGIIGFGRIGYQVAKIANALGMNILLYDPYP-NEERAKEVNGKFV-DLETLLKE 196
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
DVV I++PL E T L ++ R+ KK +++N +RG ++DT A+ A G +AG G
Sbjct: 197 SDVVTIHVPLVESTYHLINEERLKLMKKTAILINTSRGPVVDTNALVKALKEGWIAGAGL 256
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
DV+ +P PKDHP N +TPHI +T++AQ R V + + + KG
Sbjct: 257 DVFEEEPLPKDHPLTKFDNVVLTPHIGASTVEAQERAGVEVAEKVVKILKG 307
>gi|7431356|pir||C72483 probable formate dehydrogenase APE2507 - Aeropyrum
pernix (strain K1) >gi|5106212|dbj|BAA81523.1| (AP000064) 326aa
long hypothetical formate dehydrogenase [Aeropyrum pernix]
Length = 326
Frame 3 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | 326
0 150 300
Plus Strand HSPs:
Score = 305 (107.4 bits), Expect = 3.6e-26, P = 3.6e-26
Identities = 66/175 (37%), Positives = 103/175 (58%), Frame = +3
Query: 36 YDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLP 215
+DL+GKT G +G GRIG+ + +RL+PF +Y+D++RM D E+E+G ++ L +L
Sbjct: 141 FDLQGKTWGIIGLGRIGREVAKRLRPFEVRTVYFDKVRME-DAERELGVEYRS-LSRLLR 198
Query: 216 KCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYG 395
+ DVV I++PLT +TRG+ + + K V++N +RG I+D +A+A A +AG
Sbjct: 199 ESDVVSIHVPLTSETRGMIGEGELRMMKPTAVLINPSRGEIVDEEALARAVRERWIAGAA 258
Query: 396 GDVWPIQPSPKDHPWRYMPNHA-----MTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
DV+ +P P DHP A +TPHI+G DA+ R + + R KG
Sbjct: 259 VDVYSREPPPPDHPLIRAAGEADVNLILTPHIAGANTDARSRIIQFSIENIVRVLKG 315
>gi|629142|pir||S45534 phosphoglycerate dehydrogenase (EC 1.1.1.95) - Bacillus
subtilis (fragment) >gi|410116|gb|AAA67502.1| (L09228)
phosphoglycerate dehydrogenase [Bacillus subtilis]
Length = 419
Frame 3 hits (HSPs): ______________________
Annotated Domains: _____ ___
__________________________________________________
Database sequence: | | | | 419
0 150 300
__________________
Annotated Domains:
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 27..34
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 35..62
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 82..95
__________________
Plus Strand HSPs:
Score = 289 (101.7 bits), Expect = 1.8e-24, P = 1.8e-24
Identities = 66/176 (37%), Positives = 101/176 (57%), Frame = +3
Query: 24 AHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLD 203
A+ +L GKT+G VG GRIG + QR F + +D + + K+IG +
Sbjct: 24 AYVGSELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPF-LTEERAKKIGVN-SRTFE 81
Query: 204 AMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHV 383
+L D++ ++ PLT++T+GL +K IAK KKGV ++N ARG I+D A+ +A +GHV
Sbjct: 82 EVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENGHV 141
Query: 384 AGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
AG DV+ ++P P D+ P TPH+ +T +AQL AA V + + + KG
Sbjct: 142 AGAALDVFEVEP-PVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKG 196
>gi|7431354|pir||A71175 probable dehydrogenase - Pyrococcus horikoshii
>gi|3257003|dbj|BAA29686.1| (AP000002) 376aa long hypothetical
dehydrogenase [Pyrococcus horikoshii]
Length = 376
Frame 3 hits (HSPs): ________________________
__________________________________________________
Database sequence: | | | | 376
0 150 300
Plus Strand HSPs:
Score = 287 (101.0 bits), Expect = 2.9e-24, P = 2.9e-24
Identities = 63/173 (36%), Positives = 102/173 (58%), Frame = +3
Query: 36 YDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLP 215
YD+ GKT+G +G GRIG+ + +R K FN +LYY R R ++E+E+ A+F+ L+ +L
Sbjct: 188 YDVYGKTIGIIGLGRIGQAIAKRAKGFNMRILYYSRTRKE-EVERELNAEFKP-LEDLLR 245
Query: 216 KCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYG 395
+ D VV+ +PLT +T L ++ R+ KK +++N ARG ++DT A+ A G +AG G
Sbjct: 246 ESDFVVLAVPLTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAG 305
Query: 396 GDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGE 554
DV+ +P + ++ + N +TPHI + A+ A V L +GE
Sbjct: 306 LDVFEEEPYYNEELFK-LDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRGE 357
>gi|6094273|sp|O53243|SERA_MYCTU D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH)
>gi|7431374|pir||G70854 probable serA protein - Mycobacterium
tuberculosis (strain H37RV) >gi|2791593|emb|CAA16081.1| (AL021287)
serA [Mycobacterium tuberculosis]
Length = 528
Frame 3 hits (HSPs): __________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 528
0 150 300 450
__________________
Annotated Domains:
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 75..279
PFAM ACT: ACT domain 454..526
PRODOM PD000749: SERA(13) 6..73
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 75..278
PRODOM PD000700: SERA(10) 280..419
PRODOM PD005716: SERA(8) 424..508
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 136..143
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 144..171
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 191..204
PROSITE PTS_HPR_SER: PTS HPR component serine ph 403..418
__________________
Plus Strand HSPs:
Score = 291 (102.4 bits), Expect = 4.4e-24, P = 4.4e-24
Identities = 65/176 (36%), Positives = 100/176 (56%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
++ GKTVG VG GRIG+L+ QR+ F ++ YD ++ ++G + LD +L +
Sbjct: 138 EIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPY-VSPARAAQLGIELLS-LDDLLAR 195
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
D + +++P T +T GL DK +AK K GV+IVN ARG ++D A+ADA + GHV G
Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGL 255
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGEDFPE 566
DV+ +P D P + +TPH+ +T +AQ R V + + GE P+
Sbjct: 256 DVFATEPCT-DSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPD 310
>gi|3123275|sp|P35136|SERA_BACSU D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH)
>gi|7427681|pir||C69705 phosphoglycerate dehydrogenase (EC
1.1.1.95) serA - Bacillus subtilis >gi|1146196|gb|AAC83943.1|
(L47648) phosphoglycerate dehydrogenase [Bacillus subtilis]
>gi|2634742|emb|CAB14239.1| (Z99116) phosphoglycerate dehydrogenase
[Bacillus subtilis]
Length = 525
Frame 3 hits (HSPs): _________________
Annotated Domains: ________________________________________ _________
__________________________________________________
Database sequence: | | | | | 525
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00065A: D-isomer specific 2-hydroxyaci 71..112
BLOCKS BL00065B: D-isomer specific 2-hydroxyaci 135..159
BLOCKS BL00065C: D-isomer specific 2-hydroxyaci 209..259
BLOCKS BL00065D: D-isomer specific 2-hydroxyaci 269..278
Entrez np-binding site: NAD (BY SIMILARITY). 238..267
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 72..276
PFAM ACT: ACT domain 451..524
PRODOM PD000749: SERA(13) 1..70
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 72..275
PRODOM PD000700: SERA(10) 277..416
PRODOM PD005716: SERA(8) 435..521
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 133..140
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 141..168
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 188..201
__________________
Plus Strand HSPs:
Score = 289 (101.7 bits), Expect = 7.1e-24, P = 7.1e-24
Identities = 66/176 (37%), Positives = 101/176 (57%), Frame = +3
Query: 24 AHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLD 203
A+ +L GKT+G VG GRIG + QR F + +D + + K+IG +
Sbjct: 130 AYVGSELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPF-LTEERAKKIGVN-SRTFE 187
Query: 204 AMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHV 383
+L D++ ++ PLT++T+GL +K IAK KKGV ++N ARG I+D A+ +A +GHV
Sbjct: 188 EVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENGHV 247
Query: 384 AGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
AG DV+ ++P P D+ P TPH+ +T +AQL AA V + + + KG
Sbjct: 248 AGAALDVFEVEP-PVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKG 302
>gi|7431351|pir||B75057 glycerate dehydrogenase PAB2374 - Pyrococcus abyssi
(strain Orsay) >gi|5458864|emb|CAB50351.1| (AJ248287) GLYCERATE
DEHYDROGENASE [Pyrococcus abyssi]
Length = 335
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | 335
0 150 300
Plus Strand HSPs:
Score = 283 (99.6 bits), Expect = 7.7e-24, P = 7.7e-24
Identities = 61/173 (35%), Positives = 103/173 (59%), Frame = +3
Query: 36 YDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLP 215
YD+ GKT+G +G GRIG+ + +R + F+ +LYY R R ++EKE+ A+F+ LD +L
Sbjct: 147 YDVYGKTIGIIGFGRIGQAIAKRARGFDMRILYYSRTR-KPEVEKELNAEFKP-LDELLR 204
Query: 216 KCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYG 395
+ D VV+ +PL ++T + ++ R+ K+ +++N ARG ++DT+A+ A G +AG G
Sbjct: 205 ESDFVVLAVPLNKETYHMINEERLKMMKRTAILINVARGKVIDTKALIKALKEGWIAGAG 264
Query: 396 GDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGE 554
DV+ +P + + + N +TPHI T A+ A V + L +GE
Sbjct: 265 LDVYEEEPYYNEELFS-LDNVVLTPHIGSATFGAREGMAKLVAENLIAFKRGE 316
>gi|7431355|pir||D75067 probable dehydrogenase PAB1008 - Pyrococcus abyssi
(strain Orsay) >gi|5458946|emb|CAB50433.1| (AJ248287) hypothetical
DEHYDROGENASE [Pyrococcus abyssi]
Length = 333
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | 333
0 150 300
Plus Strand HSPs:
Score = 283 (99.6 bits), Expect = 7.7e-24, P = 7.7e-24
Identities = 66/182 (36%), Positives = 110/182 (60%), Frame = +3
Query: 42 LEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPKC 221
L GK VG VG G IGK + +RLKPF C + Y+ R R D+E+E+ AK+ DLD +L +
Sbjct: 144 LYGKEVGIVGMGAIGKAIARRLKPFGCEIYYWSRHRKE-DIEREVNAKYL-DLDELLEEV 201
Query: 222 DVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGGD 401
D+V++ +PLT++T + ++ R+ K + G +VN RGA++D +A+ A G + G+ D
Sbjct: 202 DIVILALPLTKETYHIINEERVKKLE-GKYLVNIGRGALIDEKALVKAIKEGKLKGFATD 260
Query: 402 VWPIQPSPKDHPWRYMPNHAMTPHISGTTIDA--QLRYAAGVKDMLDRHFKGEDFPEQNY 575
V+ +P + +R+ +TPH +G D + + A V+++L + +GE PE +
Sbjct: 261 VFEEEPVKEHELFRFKWETVLTPHYAGLGKDVLEDMGFRA-VENLL-KVLRGE-IPE-DL 316
Query: 576 IVKE 587
+ KE
Sbjct: 317 VNKE 320
>gi|3122862|sp|O33116|SERA_MYCLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH)
>gi|11251649|pir||T45418 phosphoglycerate dehydrogenase [imported]
- Mycobacterium leprae >gi|2414551|emb|CAB16440.1| (Z99263)
phosphoglycerate dehydrogenase [Mycobacterium leprae]
Length = 528
Frame 3 hits (HSPs): __________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 528
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00065A: D-isomer specific 2-hydroxyaci 74..115
BLOCKS BL00065B: D-isomer specific 2-hydroxyaci 138..162
BLOCKS BL00065C: D-isomer specific 2-hydroxyaci 212..262
BLOCKS BL00065D: D-isomer specific 2-hydroxyaci 272..281
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 75..279
PFAM ACT: ACT domain 454..527
PRODOM PD000749: SERA(13) 6..73
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 75..278
PRODOM PD000700: SERA(10) 280..419
PRODOM PD005716: SERA(8) 424..508
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 136..143
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 144..171
PROSITE D_2_HYDROXYACID_DH_2: D-isomer specific 191..204
PROSITE PTS_HPR_SER: PTS HPR component serine ph 403..418
__________________
Plus Strand HSPs:
Score = 284 (100.0 bits), Expect = 2.6e-23, P = 2.6e-23
Identities = 64/176 (36%), Positives = 98/176 (55%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
++ GKTVG VG GRIG+L+ R+ F +++ YD + ++G + D +L +
Sbjct: 138 EIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPY-VAPARAAQLGIELMS-FDDLLAR 195
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
D + +++P T +T GL DK +AK K GV+IVN ARG ++D A+ADA SGHV G
Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGL 255
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGEDFPE 566
DV+ +P D P + +TPH+ +T +AQ R V + + GE P+
Sbjct: 256 DVFATEPCT-DSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPD 310
>gi|11498419 ref|NP_069647.1| phosphoglycerate dehydrogenase (serA)
[Archaeoglobus fulgidus] >gi|3122861|sp|O29445|SERA_ARCFU
D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH) >gi|7431372|pir||E69351
phosphoglycerate dehydrogenase (serA) homolog - Archaeoglobus
fulgidus >gi|2649798|gb|AAB90429.1| (AE001048) phosphoglycerate
dehydrogenase (serA) [Archaeoglobus fulgidus]
Length = 527
Frame 3 hits (HSPs): __________________
__________________________________________________
Database sequence: | | | | | 527
0 150 300 450
Plus Strand HSPs:
Score = 283 (99.6 bits), Expect = 3.3e-23, P = 3.3e-23
Identities = 63/180 (35%), Positives = 100/180 (55%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
+L GKT G +G GR+G + +R K N+L YD ++ + ++IG K D D +L
Sbjct: 136 ELRGKTAGVIGLGRVGFEVAKRCKALEMNVLAYDPF-VSKERAEQIGVKLV-DFDTLLAS 193
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
DV+ +++P T++T GL K + K K GV++VN ARG I+D A+ +A +G VA
Sbjct: 194 SDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAALYEAIKAGKVAAAAL 253
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGEDFPEQNYI 578
DV+ +P D+P + N TPHI+ +T +AQL + + + KG P +N +
Sbjct: 254 DVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIVNMAKG--LPVRNAV 311
>gi|7431443|pir||C71165 probable dehydrogenase - Pyrococcus horikoshii
>gi|3256925|dbj|BAA29608.1| (AP000002) 333aa long hypothetical
dehydrogenase [Pyrococcus horikoshii]
Length = 333
Frame 3 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | 333
0 150 300
Plus Strand HSPs:
Score = 275 (96.8 bits), Expect = 5.4e-23, P = 5.4e-23
Identities = 64/186 (34%), Positives = 105/186 (56%), Frame = +3
Query: 30 RAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAM 209
R L GK VG +G G IGK + +RL PF L Y+ R R ++EKE+ A++ D+D +
Sbjct: 140 RIESLYGKKVGILGMGAIGKAIARRLIPFGVKLYYWSRHR-KVNVEKELKARYM-DIDEL 197
Query: 210 LPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAG 389
L K D+V++ +PLT T + ++ R+ K + G +VN RGA++D +A+ +A G + G
Sbjct: 198 LEKSDIVILALPLTRDTYHIINEERVKKLE-GKYLVNIGRGALVDEKAVTEAIKQGKLKG 256
Query: 390 YGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGEDFPEQ 569
Y DV+ +P + ++Y +TPH +G ++AQ + L + +GE PE
Sbjct: 257 YATDVFEKEPVREHELFKYEWETVLTPHYAGLALEAQEDVGFRAVENLLKVLRGE-VPE- 314
Query: 570 NYIVKE 587
+ + KE
Sbjct: 315 DLVNKE 320
>gi|7431353|pir||E72568 probable D-3-phosphoglycerate dehydrogenase APE1831 -
Aeropyrum pernix (strain K1) >gi|5105521|dbj|BAA80834.1| (AP000062)
347aa long hypothetical D-3-phosphoglycerate dehydrogenase
[Aeropyrum pernix]
Length = 347
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | 347
0 150 300
Plus Strand HSPs:
Score = 271 (95.4 bits), Expect = 1.4e-22, P = 1.4e-22
Identities = 61/183 (33%), Positives = 103/183 (56%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
+L GKT+G +G GRIG + + K F ++Y+ R R ++EKE+GA++ L+ +L +
Sbjct: 160 ELRGKTLGILGMGRIGSRVAEIGKAFGMRIIYHSRSRKR-EIEKELGAEYRS-LEDLLRE 217
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
D++ I++PLT++TR L ++ + KK ++VN RGAI+DT A+ A G +A
Sbjct: 218 SDILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAAL 277
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGEDFPEQNYI 578
DV+ +P +HP N + PH + T + +LR A + L +G+ P N +
Sbjct: 278 DVFEEEPLNPNHPLTAFKNVVLAPHAASATRETRLRMAMMAAENLVAFAQGKVPP--NLV 335
Query: 579 VKE 587
+E
Sbjct: 336 NRE 338
>gi|11499368 ref|NP_070607.1| 2-hydroxyacid dehydrogenase, putative
[Archaeoglobus fulgidus] >gi|7431350|pir||B69472 2-hydroxyacid
dehydrogenase homolog - Archaeoglobus fulgidus
>gi|2648765|gb|AAB89467.1| (AE000979) 2-hydroxyacid dehydrogenase,
putative [Archaeoglobus fulgidus]
Length = 323
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | | | | | 323
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 270 (95.0 bits), Expect = 1.8e-22, P = 1.8e-22
Identities = 59/174 (33%), Positives = 102/174 (58%), Frame = +3
Query: 36 YDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLP 215
Y+L GKT G +G G G+ + +RL+ + ++Y+D +R D+E E G +F D DA+L
Sbjct: 145 YELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHD-VRRAEDIE-EYGVEFR-DFDALLR 201
Query: 216 KCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYG 395
+ D+V +++PLTE+TRG+ + + K +++N ARG ++D A+ A +AG
Sbjct: 202 EADIVSLHVPLTEETRGMIGERELKMMKNSAILINVARGEVVDENALVRAIKERWIAGAA 261
Query: 396 GDVWPIQPSPKDHPWRYMPNHAM--TPHISGTTIDAQLRYAAGVKDMLDRHFKGED 557
DV+ +P P+ + +H + TPHI+G T +A+LR + + R +GE+
Sbjct: 262 LDVFAKEP-PEGSELLELKSHNVIFTPHIAGATNEARLRIIREAMENIGRALRGEE 316
>gi|7431365|pir||S48189 hydroxypyruvate reductase (EC 1.1.1.81) -
Hyphomicrobium methylovorum >gi|1304133|dbj|BAA06662.1| (D31857)
hydroxypyruvate reductase [Hyphomicrobium methylovorum]
Length = 322
Frame 3 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | | | | | 322
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 269 (94.7 bits), Expect = 2.3e-22, P = 2.3e-22
Identities = 58/174 (33%), Positives = 94/174 (54%), Frame = +3
Query: 42 LEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPKC 221
L+ KT+G G G+IG+ L QR + F+ N+ YYD R ++E + A + + LD++L
Sbjct: 146 LDNKTLGIYGFGKIGQALAQRARGFDMNVHYYDIYRAKPEVEAKYNATYHDSLDSLLKVS 205
Query: 222 DVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGGD 401
IN P T +TR F+K I K +G ++VN ARG ++ + A SG +A G D
Sbjct: 206 QFFSINAPSTPETRYFFNKETIEKLPQGAIVVNTARGDLVKDDDVIAALKSGRLAYAGFD 265
Query: 402 VWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGEDFP 563
V+ +P+ + + +PN + PH+ I+A+ + D +D F G+D P
Sbjct: 266 VFAGEPNINEGYYD-LPNTFLFPHLGSAAIEARNQMGFEALDNIDAFFAGKDMP 318
>gi|3859695|emb|CAA21970.1| (AL033497) YNL274C homologue [Candida albicans]
Length = 342
Frame 3 hits (HSPs): _______________________
__________________________________________________
Database sequence: | | | | 342
0 150 300
Plus Strand HSPs:
Score = 269 (94.7 bits), Expect = 2.3e-22, P = 2.3e-22
Identities = 57/151 (37%), Positives = 93/151 (61%), Frame = +3
Query: 45 EGKTVGTVGAGRIGKLLLQRLKPFNCN-LLYYDRLRMNTDLEKEIGAKFEEDLDAMLPKC 221
+GK VG +G G IG+ + RLKPF + ++YY+R +++++LEK GA++ +D + +
Sbjct: 163 QGKVVGILGMGGIGRAIRDRLKPFGFDRIVYYNRKQLSSELEK--GAEYVT-MDELFKQS 219
Query: 222 DVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGGD 401
DV++I +PL +TR L DK I K K GVV+VN ARGAI+D + + + SG + +G D
Sbjct: 220 DVIIIGVPLNAKTRHLIDKEAIQKMKDGVVLVNIARGAIIDEKHLPELIKSGKIGAFGAD 279
Query: 402 VWPIQPSPKDHPWRYMPNHAMTPHISGTTIDA 497
V+ +P +PN PH+ +++A
Sbjct: 280 VFEHEPEVSPELVN-LPNVVALPHMGTHSVEA 310
>gi|10640058|emb|CAC11910.1| (AL445065) 2-hydroxyacid dehydrogenase related
protein [Thermoplasma acidophilum]
Length = 309
Frame 3 hits (HSPs): _____________________________
__________________________________________________
Database sequence: | | | | | | | | 309
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 269 (94.7 bits), Expect = 2.3e-22, P = 2.3e-22
Identities = 60/176 (34%), Positives = 96/176 (54%), Frame = +3
Query: 30 RAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAM 209
R+ DL GKT G VG G IG+ L RL PF ++Y D RM+ E+E GA F LD +
Sbjct: 130 RSSDLMGKTFGIVGMGSIGRALAARLLPFKVAIIYNDTKRMSEAEEEEYGATFVS-LDRL 188
Query: 210 LPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAG 389
L DV+ +++PL E TR +F+ +R K G + +N +RG ++ + + +A +
Sbjct: 189 LSDSDVISVHVPLNETTRHMFNSSRFGLMKDGAIFINTSRGEVVVEKDLIEAIQKKGIRA 248
Query: 390 YGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGED 557
G DV+ +P + P + N +PHI+G T ++Q+R+ + R+ +G D
Sbjct: 249 -GLDVFEHEPPDPNSPLFRLENTLFSPHIAGVTAESQMRFFRETIANVMRYMQGYD 303
>gi|7297831|gb|AAF53080.1| (AE003631) CG6287 gene product [Drosophila
melanogaster]
Length = 332
Frame 3 hits (HSPs): _________________________
__________________________________________________
Database sequence: | | | | 332
0 150 300
Plus Strand HSPs:
Score = 268 (94.3 bits), Expect = 3.0e-22, P = 3.0e-22
Identities = 60/163 (36%), Positives = 93/163 (57%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
+L GKT+ +G GRIG+ + R+K + ++ YD + T+ E + + L+ + P
Sbjct: 142 ELYGKTLAVLGLGRIGREVAIRMKTWGMRIIGYDPI--TTEAEAKAAGIEKMTLEEIWPL 199
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
D + ++ PL TR L +AKCK+GV +VN ARG I+D QA+ D SG VAG
Sbjct: 200 ADYITVHTPLIPATRNLISAETLAKCKQGVKVVNVARGGIIDEQAVLDGLESGKVAGAAF 259
Query: 399 DVWPIQPSPKDHPWRYMPNH---AMTPHISGTTIDAQLRYAAGVKD 527
DV+P +P PK + + +H TPH+ +T +AQ+R A V +
Sbjct: 260 DVYPEEP-PKSAVTKALISHPKVVATPHLGASTSEAQVRVAVEVAE 304
>gi|6324055 ref|NP_014125.1| Ynl274cp [Saccharomyces cerevisiae]
>gi|1730640|sp|P53839|YN14_YEAST HYPOTHETICAL 38.8 KD PROTEIN IN
MET2-SEC2 INTERGENIC REGION >gi|2131951|pir||S63248 hypothetical
protein YNL274c - yeast (Saccharomyces cerevisiae)
>gi|1302340|emb|CAA96182.1| (Z71550) ORF YNL274c [Saccharomyces
cerevisiae]
Length = 350
Frame 3 hits (HSPs): ____________________
__________________________________________________
Database sequence: | | | | 350
0 150 300
Plus Strand HSPs:
Score = 267 (94.0 bits), Expect = 3.8e-22, P = 3.8e-22
Identities = 60/138 (43%), Positives = 86/138 (62%), Frame = +3
Query: 6 AGVAGIAHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNC-NLLYYDRLRMNTDLEKEIGA 182
AG A + YD EGKTVG +G GRIG+ +L+RLKPF N +Y++R ++ + E+E G
Sbjct: 149 AGPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFENFIYHNRHQLPS--EEEHGC 206
Query: 183 KFEEDLDAMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIAD 362
++ + L + D+V +N+PL T L + I K K GVVIVN ARGA++D QA+ D
Sbjct: 207 EYV-GFEEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTD 265
Query: 363 ACSSGHVAGYGGDVWPIQP 419
A SG + G DV+ +P
Sbjct: 266 ALRSGKIRSAGLDVFEYEP 284
>gi|3122874|sp|Q58424|SERA_METJA D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PGDH)
>gi|2129189|pir||A64427 phosphoglycerate dehydrogenase (EC
1.1.1.95) - Methanococcus jannaschii >gi|1591676|gb|AAB99020.1|
(U67544) phosphoglycerate dehydrogenase (serA) [Methanococcus
jannaschii]
Length = 524
Frame 3 hits (HSPs): __________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | 524
0 150 300 450
__________________
Annotated Domains:
BLOCKS BL00065A: D-isomer specific 2-hydroxyaci 72..113
BLOCKS BL00065B: D-isomer specific 2-hydroxyaci 136..160
BLOCKS BL00065C: D-isomer specific 2-hydroxyaci 211..261
BLOCKS BL00065D: D-isomer specific 2-hydroxyaci 271..280
Entrez np-binding site: NAD (BY SIMILARITY). 240..269
PFAM 2-Hacid_DH: D-isomer specific 2-hydroxya 73..278
PFAM ACT: ACT domain 451..522
PRODOM PD000749: SERA(13) 1..71
PRODOM PD000699: SAHH(31) SERA(13) LDHD(6) 73..277
PRODOM PD000700: SERA(10) 280..415
PRODOM PD005716: SERA(8) 428..521
PROSITE ATP_GTP_A: ATP/GTP-binding site motif A 134..141
PROSITE D_2_HYDROXYACID_DH_1: D-isomer specific 142..169
__________________
Plus Strand HSPs:
Score = 269 (94.7 bits), Expect = 1.1e-21, P = 1.1e-21
Identities = 55/175 (31%), Positives = 101/175 (57%), Frame = +3
Query: 30 RAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAM 209
+ +L GKT+G +G GRIG+ +++R K F N++ YD + ++ + +G + +D++ +
Sbjct: 133 KGIELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPY-IPKEVAESMGVELVDDINEL 191
Query: 210 LPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAG 389
+ D + +++PLT +TR + + +IA KK +IVN ARG ++D +A+ +A G +
Sbjct: 192 CKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRA 251
Query: 390 YGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGE 554
DV+ +P PKD+P + N TPH +T +AQ V + + + +GE
Sbjct: 252 AALDVFEEEP-PKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVLRGE 305
>gi|7431363|pir||B72257 D-3-phosphoglycerate dehydrogenase - Thermotoga
maritima (strain MSB8) >gi|4981965|gb|AAD36472.1|AE001793_2
(AE001793) D-3-phosphoglycerate dehydrogenase [Thermotoga maritima]
Length = 306
Frame 3 hits (HSPs): _____________________________
__________________________________________________
Database sequence: | | | | | | | | 306
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 262 (92.2 bits), Expect = 1.3e-21, P = 1.3e-21
Identities = 64/175 (36%), Positives = 100/175 (57%), Frame = +3
Query: 24 AHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLD 203
A + +L GKT+G +G G IG+ + +R F ++ YD + TDL E DLD
Sbjct: 134 ALKGKELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAYDPAKPETDLPVEY-----VDLD 188
Query: 204 AMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHV 383
+ + D + +++PLTE TR + ++ IAK K GV+IVN ARG +D +A+ + SG V
Sbjct: 189 TLFKESDFISLHVPLTESTRHIINRESIAKMKDGVIIVNTARGGTIDEEALYEEVVSGKV 248
Query: 384 AGYGGDVWPIQPSPKDHPWRYM---PNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFK 548
G DV+ ++P P D R + N TPHI +T +AQ R G+ +++++ FK
Sbjct: 249 YAAGLDVFEVEP-PTDEIRRKLLSLDNVVATPHIGASTAEAQRR--VGI-ELVEKIFK 302
>gi|10175937|dbj|BAB07033.1| (AP001518) glycerate dehydrogenase [Bacillus
halodurans]
Length = 324
Frame 3 hits (HSPs): _______________________
__________________________________________________
Database sequence: | | | | | | | | 324
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 261 (91.9 bits), Expect = 1.6e-21, P = 1.6e-21
Identities = 57/148 (38%), Positives = 83/148 (56%), Frame = +3
Query: 48 GKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPKCDV 227
G T+G +G GRIG+ + +R K FN LLY++R R N EKE+GA + LD +L + D
Sbjct: 145 GTTLGIIGMGRIGQAVAKRAKGFNMTLLYHNRSR-NEQAEKELGATYCS-LDHLLARSDY 202
Query: 228 VVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGGDVW 407
VV+ P T++TR + + K K +N +RG +D QA+ A + G +AG G DV+
Sbjct: 203 VVLLAPSTDETRKMMGPAQFQKMKSTAHFINTSRGTNVDEQALYRALTEGWIAGAGLDVY 262
Query: 408 PIQPSPKDHPWRYMPNHAMTPHISGTTI 491
+P DHP +PN PHI +
Sbjct: 263 EKEPISADHPLVQLPNVVALPHIGSAEV 290
>gi|11251856|pir||T42743 hypothetical protein - fission yeast
(Schizosaccharomyces pombe) >gi|1749578|dbj|BAA13847.1| (D89185)
similar to Saccharomyces cerevisiae ORF YNL274C, EMBL Accession
Number Z71550 [Schizosaccharomyces pombe]
Length = 334
Frame 3 hits (HSPs): _________________________
__________________________________________________
Database sequence: | | | | 334
0 150 300
Plus Strand HSPs:
Score = 258 (90.8 bits), Expect = 3.4e-21, P = 3.4e-21
Identities = 60/163 (36%), Positives = 94/163 (57%), Frame = +3
Query: 33 AYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAML 212
++D EGKT+G +G G IGK + +R + F+ ++Y++R + + E E GA+F D +L
Sbjct: 151 SHDPEGKTLGILGLGGIGKTMAKRARAFDMKIVYHNRTPLPEE-EAE-GAEFVS-FDDLL 207
Query: 213 PKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGY 392
K DV+ +N+PL TR + K K K+G+VIVN ARGA+MD A+ +A G V
Sbjct: 208 AKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSA 267
Query: 393 GGDVWPIQPSPKDHPWRYMPNHA--MTPHISGTTIDAQLRYAAGV 521
G DV+ + PK HP + N + PH+ +++ Q + V
Sbjct: 268 GLDVF--EEEPKIHPG-LLENEKVILLPHLGTNSLETQYKMECAV 309
>gi|7492328|pir||T41705 probable 2-hydroxyacid dehydrogenase - fission yeast
(Schizosaccharomyces pombe) >gi|3395556|emb|CAA20140.1| (AL031180)
putative 2-hydroxyacid dehydrogenase [Schizosaccharomyces pombe]
Length = 334
Frame 3 hits (HSPs): _________________________
__________________________________________________
Database sequence: | | | | 334
0 150 300
Plus Strand HSPs:
Score = 258 (90.8 bits), Expect = 3.4e-21, P = 3.4e-21
Identities = 60/163 (36%), Positives = 94/163 (57%), Frame = +3
Query: 33 AYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAML 212
++D EGKT+G +G G IGK + +R + F+ ++Y++R + + E E GA+F D +L
Sbjct: 151 SHDPEGKTLGILGLGGIGKTMAKRARAFDMKIVYHNRTPLPEE-EAE-GAEFVS-FDDLL 207
Query: 213 PKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGY 392
K DV+ +N+PL TR + K K K+G+VIVN ARGA+MD A+ +A G V
Sbjct: 208 AKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSA 267
Query: 393 GGDVWPIQPSPKDHPWRYMPNHA--MTPHISGTTIDAQLRYAAGV 521
G DV+ + PK HP + N + PH+ +++ Q + V
Sbjct: 268 GLDVF--EEEPKIHPG-LLENEKVILLPHLGTNSLETQYKMECAV 309
>gi|7522478|pir||T39682 probable glycerate-and formate-dehydrogenase - fission
yeast (Schizosaccharomyces pombe) (fragment)
Length = 195
Frame 3 hits (HSPs): _____________________________________
__________________________________________________
Database sequence: | | | | | 195
0 50 100 150
Plus Strand HSPs:
Score = 257 (90.5 bits), Expect = 4.4e-21, P = 4.4e-21
Identities = 57/145 (39%), Positives = 76/145 (52%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
D GK VG +G G IGK Q++ P C ++Y++R R+ + EK +GA F D +L
Sbjct: 11 DPYGKRVGIIGMGAIGKSFAQKILPLGCEIVYHNRNRLEAEEEKRLGASFVS-FDELLSS 69
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
DV+ IN PLT T L K K GV I+N ARGAI++ A A SG VA G
Sbjct: 70 SDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGL 129
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPH 473
DV+ +P+P W + PH
Sbjct: 130 DVFLNEPTPNKF-WLECDKVTIQPH 153
>gi|9968732|emb|CAA21922.2| (AL033389) putative glycerate-and
formate-dehydrogenase [Schizosaccharomyces pombe]
Length = 185
Frame 3 hits (HSPs): _______________________________________
__________________________________________________
Database sequence: | | | | | 185
0 50 100 150
Plus Strand HSPs:
Score = 257 (90.5 bits), Expect = 4.4e-21, P = 4.4e-21
Identities = 57/145 (39%), Positives = 76/145 (52%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
D GK VG +G G IGK Q++ P C ++Y++R R+ + EK +GA F D +L
Sbjct: 1 DPYGKRVGIIGMGAIGKSFAQKILPLGCEIVYHNRNRLEAEEEKRLGASFVS-FDELLSS 59
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
DV+ IN PLT T L K K GV I+N ARGAI++ A A SG VA G
Sbjct: 60 SDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGL 119
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPH 473
DV+ +P+P W + PH
Sbjct: 120 DVFLNEPTPNKF-WLECDKVTIQPH 143
>gi|2290989|gb|AAC46259.1| (AF006000) D-3-phosphoglycerate dehydrogenase
homolog [Bordetella pertussis]
Length = 399
Frame 3 hits (HSPs): ________________________
__________________________________________________
Database sequence: | | | | 399
0 150 300
Plus Strand HSPs:
Score = 258 (90.8 bits), Expect = 5.0e-21, P = 5.0e-21
Identities = 60/187 (32%), Positives = 104/187 (55%), Frame = +3
Query: 33 AYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIG-AKFEEDLDAM 209
AY+ GKT+G VG G IG + + ++++D + + +G A+ L +
Sbjct: 137 AYEARGKTLGIVGYGNIGSQISTLAEAIGMRVVFFD-----VEAKLPLGNARAAGSLAEL 191
Query: 210 LPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAG 389
L + DVV +++P + T+ + + + +A+ K+G +++N +RG ++D QA+ DA +SGH+AG
Sbjct: 192 LEQADVVTLHVPGGKSTQNIVNADTLARMKRGAILINASRGTVVDIQALHDALASGHLAG 251
Query: 390 YGGDVWPIQPSPKDHPWRY----MPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGE- 554
DV+P +P D P MPN +TPHI G+T ++Q V + L R +
Sbjct: 252 AALDVFPTEPKSADEPLASPLIGMPNVVLTPHIGGSTQESQENIGREVAEKLVRFLQAGT 311
Query: 555 -----DFPEQNY 575
+FPE +Y
Sbjct: 312 TKSAVNFPELSY 323
>gi|7496777|pir||T19602 hypothetical protein C31C9.2 - Caenorhabditis elegans
>gi|3874647|emb|CAB05694.1| (Z83219) contains similarity to Pfam
domain: PF00389 (D-isomer specific 2-hydroxyacid dehydrogenases),
Score=247.0, E-value=2.5e-101, N=1~cDNA EST EMBL:T00729 comes from
this gene~cDNA EST yk636a9.3 comes from this gene~cDNA EST
yk636a9.5 comes from th>
Length = 322
Frame 3 hits (HSPs): ___________________________
__________________________________________________
Database sequence: | | | | | | | | 322
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 254 (89.4 bits), Expect = 9.1e-21, P = 9.1e-21
Identities = 62/171 (36%), Positives = 104/171 (60%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEE--DLDAML 212
++ G+T+ +G GRIG + RL+ F ++ +D M T + E AK E L+ +
Sbjct: 142 EVYGRTLAVLGLGRIGSEVAVRLQAFGMKVIGFDP--MVTKEQAE--AKNIELLSLEQIW 197
Query: 213 PKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGY 392
P+ D + +++PL +QT L +K +AKCKKGV I+N ARG I++ + ++ ++GH G
Sbjct: 198 PQADYITVHVPLIKQTENLINKETLAKCKKGVRIINVARGGIVNEVDLVESLNAGHAKGA 257
Query: 393 GGDVWPIQPSPKDHPWRYMPNHAM---TPHISGTTIDAQLRYAAGVKDMLDRHFKG 551
DV+ +P P +R + +H + TPH+ +TIDAQLR A+ + D + ++ KG
Sbjct: 258 AFDVFEQEP-PT---FRELIDHPLVIATPHLGASTIDAQLRVASEIADNIVQYNKG 309
>gi|10174219|dbj|BAB05321.1| (AP001512) D-3-phosphoglycerate dehydrogenase
[Bacillus halodurans]
Length = 540
Frame 3 hits (HSPs): _________________
__________________________________________________
Database sequence: | | | | | 540
0 150 300 450
Plus Strand HSPs:
Score = 261 (91.9 bits), Expect = 9.2e-21, P = 9.2e-21
Identities = 66/185 (35%), Positives = 94/185 (50%), Frame = +3
Query: 24 AHRAYDLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLD 203
A + +L GKT+G +G GRIG + +R K F +D EK +G LD
Sbjct: 145 AFQGTELRGKTLGIIGFGRIGSQIAKRAKAFEMTPYVFDPFLTKARAEK-LGVTVAS-LD 202
Query: 204 AMLPKCDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHV 383
+L D++ ++ PLT++T+GL I K KKGV ++N ARG I+D +A+ GH+
Sbjct: 203 DVLQVADIITVHTPLTKETKGLLGMKNIGKTKKGVFLINCARGGIIDEEALKHYLREGHI 262
Query: 384 AGYGGDVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAGVKDMLDRHFKGEDFP 563
AG DV+ +P D N TPHI+ +T +AQL A V + HF E P
Sbjct: 263 AGAALDVFEEEPVA-DEELLAFDNVIATPHIAASTKEAQLNVAEQVSQEV-LHFL-EGNP 319
Query: 564 EQNYI 578
N I
Sbjct: 320 VSNSI 324
>gi|7471789|pir||A75414 D-3-phosphoglycerate dehydrogenase - Deinococcus
radiodurans (strain R1) >gi|6459038|gb|AAF10861.1|AE001976_4
(AE001976) D-3-phosphoglycerate dehydrogenase [Deinococcus
radiodurans]
Length = 544
Frame 3 hits (HSPs): _________________
__________________________________________________
Database sequence: | | | | | 544
0 150 300 450
Plus Strand HSPs:
Score = 260 (91.5 bits), Expect = 1.2e-20, P = 1.2e-20
Identities = 56/166 (33%), Positives = 94/166 (56%), Frame = +3
Query: 39 DLEGKTVGTVGAGRIGKLLLQRLKPFNCNLLYYDRLRMNTDLEKEIGAKFEEDLDAMLPK 218
+L KT+G VG GRIG ++ R + + N++ YD E+ +G + LD +L +
Sbjct: 152 ELTDKTLGIVGLGRIGSIVADRAQGLHMNVVAYDPYVPENKFER-LGVQRAASLDELLGQ 210
Query: 219 CDVVVINMPLTEQTRGLFDKNRIAKCKKGVVIVNNARGAIMDTQAIADACSSGHVAGYGG 398
D + ++ PLT++TRG+ + +A K+ ++VN ARG I++ QA+ +A +GH+ G
Sbjct: 211 VDALTVHTPLTDETRGMIGERELALLKRDAIVVNAARGGIIEEQALVNALHAGHLFAAGV 270
Query: 399 DVWPIQPSPKDHPWRYMPNHAMTPHISGTTIDAQLRYAAG-VKDMLD 536
DV+ +P +H + PN +T H+ T +AQ R A V +LD
Sbjct: 271 DVFVDEPPTAEHIFLGAPNLGITAHLGANTREAQERVGAEIVSRVLD 317
WARNING: HSPs involving 187 database sequences were not reported due to the
limiting value of parameter B = 50.
Parameters:
filter=none
matrix=BLOSUM62
V=50
B=50
E=10
gi
H=1
sort_by_pvalue
echofilter
ctxfactor=5.99
Query ----- As Used ----- ----- Computed ----
Frame MatID Matrix name Lambda K H Lambda K H
Std. 0 BLOSUM62 0.318 0.135 0.401
+3 0 BLOSUM62 0.318 0.135 0.401 0.320 0.138 0.419
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+2 0 BLOSUM62 0.318 0.135 0.401 0.374 0.164 0.800
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+1 0 BLOSUM62 0.318 0.135 0.401 0.349 0.152 0.490
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-1 0 BLOSUM62 0.318 0.135 0.401 0.352 0.151 0.575
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-2 0 BLOSUM62 0.318 0.135 0.401 0.329 0.137 0.453
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-3 0 BLOSUM62 0.318 0.135 0.401 0.345 0.146 0.518
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
Query
Frame MatID Length Eff.Length E S W T X E2 S2
+3 0 201 201 10. 77 3 12 22 0.094 35
31 0.10 38
+2 0 201 200 10. 77 3 12 22 0.094 35
31 0.10 38
+1 0 202 201 10. 77 3 12 22 0.094 35
31 0.10 38
-1 0 202 201 10. 77 3 12 22 0.094 35
31 0.10 38
-2 0 201 200 10. 77 3 12 22 0.094 35
31 0.10 38
-3 0 201 200 10. 77 3 12 22 0.094 35
31 0.10 38
Statistics:
Database: /usr/local/dot5/sl_home/beauty/seqdb/blast/nr
Title: nr
Release date: unknown
Posted date: 4:06 PM CST Feb 28, 2001
Format: BLAST
# of letters in database: 197,782,623
# of sequences in database: 625,274
# of database sequences satisfying E: 237
No. of states in DFA: 595 (59 KB)
Total size of DFA: 250 KB (256 KB)
Time to generate neighborhood: 0.01u 0.01s 0.02t Elapsed: 00:00:00
No. of threads or processors used: 6
Search cpu time: 209.18u 1.21s 210.39t Elapsed: 00:01:10
Total cpu time: 209.26u 1.24s 210.50t Elapsed: 00:01:10
Start: Fri Jan 18 18:45:15 2002 End: Fri Jan 18 18:46:25 2002
WARNINGS ISSUED: 2
Annotated Domains Database: March 14, 2000
Release Date: March 14, 2000