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1: J Am Chem Soc. 2008 Apr 16;130(15):5014-5. Epub 2008 Mar 18.Click here to read Links

Hadamard amino-acid-type edited NMR experiment for fast protein resonance assignment.

IBS, Institut de Biologie Structurale Jean-Pierre Ebel, 41 rue Jules Horowitz, F-38027 Grenoble, France.

An original Hadamard-encoding scheme allows discrimination among seven amino acid types in a single two-dimensional NMR experiment. Combined with hyperdimensional NMR techniques, this presents a promising new method for fast, automated backbone resonance assignment of proteins in only a few hours time.

PMID: 18345629 [PubMed - indexed for MEDLINE]