Hadamard amino-acid-type edited NMR experiment for fast protein resonance assignment.
IBS, Institut de Biologie Structurale Jean-Pierre Ebel, 41 rue Jules Horowitz, F-38027 Grenoble, France.
An original Hadamard-encoding scheme allows discrimination among seven amino acid types in a single two-dimensional NMR experiment. Combined with hyperdimensional NMR techniques, this presents a promising new method for fast, automated backbone resonance assignment of proteins in only a few hours time.
PMID: 18345629 [PubMed - indexed for MEDLINE]