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Document Number | 1351 |
|---|---|
Primary Title | Effects of Temperature and Membrane Fatty Acid Composition on Butanol Tolerance of Clostridium acetobutylicum |
Author Name | Kuhn, R. H.;Linden, J. C. |
Author Affiliation | Colorado State Univ., Fort Collins, CO |
Editor Name | Scott, C. D. |
Conference Date | 05/13/1986 |
Conference Name | Gatlinburg, TN,13 May 1986 |
Published Date | 01/01/1986 |
Detailed Publish Date | 1986 |
Title Source | Biotechnology and Bioengineering Symposium. Proceedings of the 8th Symposium on Biotechnology for Fuels and Chemicals |
Volume Number | 17 |
Page Range | 197-207 |
Page Count | 11 |
Document Type | CONFERENCE PAPER |
Publisher Name | John Wiley and Sons, New York, NY |
Abstract | Several factors affecting the tolerance of C. acetobutylicum to butanol were investigated. Butanol was found to affect membrane integrity, causing an increase in passive proton leakage. Effects of butanol on proton influx correlated well with effects on growth. At toxic levels of butanol (0.25 M), the initial rate of passive proton influx was enhanced by two orders of magnitude. Cells grown in palmitic acid-supplemented medium were hypersensitive to butanol, while those grown in elaidic acid were inhibited to a similar extent as the control. Increasing temperature was found to have a deleterious effect on butanol tolerance. |
ISBN ISSN | 05726565 |
Copyright Status | Y - Copyrighted--no reprint permission, |
Copyright Statement | Copyright 1993 by the Royal Society of Chemistry |
Document Owner | B |