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   Laboratory of Kidney and Electrolyte Metabolism
Urinary Exosome Protein Database
This database of urinary exosome proteins is based on published protein mass spectrometry data from the NHLBI Laboratory of Kidney and Electrolyte Metabolism. All data are from urinary exosomes isolated from healthy human volunteers. Figure on the right illustrates mechanism of exosome formation and excretion. In the first step of the process, apical membrane proteins undergo endocytosis. Second, the endosome is targeted to the multivesicular body (MVB). The signal that marks plasma membrane proteins for incorporation into MVB is mono-ubiquitination. In the third step, the endosome fuses with the MVB. Consequently, the apical plasma membrane proteins are segregated in the MVB outer membranes and internalized by membrane invagination. Finally, the outer membrane of the MVB fuses with the apical plasma membrane releasing its internal vesicles, called ‘exosomes’, in the urinary space. Exosomes contain both membrane and cytosolic proteins.
Reference: Pisitkun T, Shen RF, Knepper MA. Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13368-73.
Current Database Size: 304 proteins (Download Urinary Exosome Protein Database in CSV file format).
The Urinary Exosome Protein Database was created by Trairak Pisitkun and Mark A. Knepper.
Contact us with questions or comments.
               
Protein Name   Accession Number   Gene Name Number of Unique Peptide   Number of Total Spectra   Mw (Da)   pI   Subcellular Localization
ADP-ribosylation factor 1   NP_001649   ARF1 6   27   20697   6.31   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
ADP-ribosylation factor 3   NP_001650   ARF3 6   27   20601   6.84   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
ADP-ribosylation factor 4    NP_001651   ARF4 1   4   20511   6.60   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
ADP-ribosylation factor 5   NP_001653   ARF5 1   3   20530   6.30   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
ADP-ribosylation factor 6    NP_001654   ARF6 4   11   20082   9.04   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
ADP-ribosylation factor-like 3   NP_004302   ARL3 1   1   20456   6.74   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Alix; Programmed cell death 6 interacting protein   NP_037506   PDCD6IP 12   69   96023   6.13   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Annexin 5   NP_001145   ANXA5 7   15   35937   4.94   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Annexin A11   NP_001148   ANXA11 13   113   54390   7.53   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Annexin A2   NP_001002858   ANXA2 6   40   38604   7.57   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Annexin A3   NP_005130   ANXA3 2   2   36375   5.63   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Annexin IV   NP_001144   ANXA4 7   23   36085   5.84   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Annexin VI   NP_001146   ANXA6 1   1   75904   5.51   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Annexin VII   NP_001147   ANXA7 2   8   50316   6.25   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Arfaptin 1   NP_055262   ARFIP1 1   1   38599   6.10   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Calpain 7   NP_055111   CAPN7 3   4   92652   7.55   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Cell division cycle 42 isoform 1   NP_001782   CDC42 4   13   21259   6.16   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Chloride intracellular channel 4   NP_039234   CLIC4 1   2   28772   5.45   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Chromatin modifying protein 1B   NP_065145   CHMP1B 2   4   22109   7.81   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Chromatin modifying protein 2A   NP_055268   CHMP2A 1   16   25104   5.88   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Chromatin modifying protein 2B   NP_054762   CHMP2B 3   10   23907   8.81   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Chromatin modifying protein 4B   NP_789782   CHMP4B 2   3   24950   4.76   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Chromatin modifying protein 5   NP_057494   CHMP5 3   24   24571   4.68   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Copine III    NP_003900   CPNE3 5   13   60131   5.60   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Copine V   NP_065990   CPNE5 2   5   65734   5.65   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Copine VIII    NP_705898   CPNE8 2   5   63108   5.66   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
EH-domain containing 1   NP_006786   EHD1 2   4   60627   6.35   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
EH-domain containing 3    NP_055415   EHD3 2   4   60887   6.12   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
EH-domain containing 4   NP_644670   EHD4 4   7   61175   6.33   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Hypothetical protein LOC129531   NP_620153   LOC129531 3   8   29314   8.12   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Hypothetical protein LOC148362   NP_653296   C1orf58 10   82   46464   7.55   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
N-ethylmaleimide-sensitive factor attachment protein, alpha    NP_003818   NAPA 1   1   33247   5.23   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Penta-EF hand domain containing 1   NP_036524   PEF1 2   5   30381   6.10   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Phosphoinositide-3-kinase, class 2, beta polypeptide   NP_002637   PIK3C2B 1   1   184826   6.87   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Programmed cell death 6   NP_037364   PDCD6 6   23   21868   5.16   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Protein kinase C and casein kinase substrate in neurons 3   NP_057307   PACSIN3 1   1   48487   5.83   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB1A   NP_004152   RAB1A 2   11   22678   5.93   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB1B   NP_112243   RAB1B 2   11   22171   5.55   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB2   NP_002856   RAB2 4   4   23546   6.08   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB3A or RAB3C or RAB4A or RAB4B or RAB9B or RAB30 or RAB37 or RAB39B        RAB3A, RAB3C, RAB4A, RAB4B, RAB9B, RAB30, RAB37, RAB39B 1   18           CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB3B   NP_002858   RAB3B 1   2   24758   4.85   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB3D   NP_004274   RAB3D 1   1   24267   4.76   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB5A   NP_004153   RAB5A 3   6   23659   8.32   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB5B   NP_002859   RAB5B 6   13   23707   8.29   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB5C   NP_004574   RAB5C 5   30   23568   8.87   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB6A or RAB6B or RAB27A or RAB34 or RAB39       RAB6A, RAB6B, RAB27A, RAB34, RAB39 1   18           CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB7   NP_004628   RAB7 5   14   23490   6.39   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB8   NP_005361   RAB8A 4   10   23668   9.15   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB8B   NP_057614   RAB8B 1   1   23584   9.15   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB10   NP_057215   RAB10 2   4   22469   8.80   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB 11A   NP_004654   RAB11A 4   5   24394   6.12   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB11B   NP_004209   RAB11B 4   5   24574   5.86   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB13   NP_002861   RAB13 1   1   22774   9.27   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB14    NP_057406   RAB14 2   7   23897   5.85   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB21   NP_055814   RAB21 2   2   24348   8.11   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB27B   NP_004154   RAB27B 1   3   24608   5.35   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB33B   NP_112586   RAB33B 1   18   25718   6.70   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAB35   NP_006852   RAB35 2   10   23025   8.53   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
RAP1B   NP_056461   RAP1B 5   13   20825   5.65   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Ras homolog gene family, member A    NP_001655   RHOA 4   8   21768   5.83   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Ras homolog gene family, member G   NP_001656   RHOG 1   2   21339   8.41   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Ras-related C3 botulinum toxin substrate 1   NP_008839   RAC1 6   15   21450   8.77   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Related RAS viral (r-ras) oncogene homolog 2   NP_036382   RRAS2 2   10   23400   5.74   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Ring finger protein 11    NP_055187   RNF11 1   28   17444   4.64   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
S100 calcium binding protein A11 (calgizzarin)   NP_005611   S100A11 4   9   11740   6.56   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
S100 calcium-binding protein A6   NP_055439   S100A6 2   5   10180   5.32   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
SEC31-like 1 isoform 1   NP_055748   SEC31L1 1   1   133015   6.43   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Sorcin   NP_003121   SRI 1   4   21676   5.32   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Sorting nexin associated golgi protein 1   NP_443102   SNAG1 1   5   68880   5.43   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Tumor susceptibility gene 101    NP_006283   TSG101 7   13   43944   6.06   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Ubiquitin   NP_066289   UBC 4   85   8565   6.56   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Ubiquitin-conjugating enzyme E2-like    NP_060784   UEV3 4   8   42268   5.94   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Ubiquitin-conjugating enzyme E2N   NP_003339   UBE2N 1   2   17138   6.13   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Vacuolar protein sorting 28 isoform 1   NP_057292   VPS28 6   24   25425   5.37   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Vacuolar protein sorting factor 4A   NP_037377   VPS4A 7   52   48898   7.64   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Vacuolar protein sorting factor 4B   NP_004860   VPS4B 7   52   49302   6.75   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
Vesicle-associated membrane protein 3 (cellubrevin)   NP_004772   VAMP3 1   1   11309   8.89   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
v-Ha-ras Harvey rat sarcoma viral oncogene homolog   NP_005334   HRAS 2   7   21298   5.16   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
v-ral simian leukemia viral oncogene homolog B   NP_002872   RALB 2   4   23409   6.24   CYTOPLASM (ENDOSOMAL TRAFFICKING) 
6-phosphogluconolactonase    NP_036220   PGLS 1   1   27547   5.70   CYTOPLASM
Abhydrolase domain containing 14B   NP_116139   ABHD14B 2   4   22346   5.94   CYTOPLASM
Adenine phosphoribosyltransferase   NP_000476   APRT 2   2   19608   5.78   CYTOPLASM
Aldo-keto reductase family 1, member B1   NP_001619   AKR1B1 2   7   35853   6.52   CYTOPLASM
Aldolase A   NP_000025   ALDOA 2   4   39420   8.30   CYTOPLASM
Aldolase B   NP_000026   ALDOB 3   12   39473   8.01   CYTOPLASM
Aminoacylase 1   NP_000657   ACY1 1   1   45885   5.77   CYTOPLASM
Argininosuccinate synthetase    NP_000041   ASS 1   1   46426   8.36   CYTOPLASM
ATP citrate lyase   NP_001087   ACLY 1   1   120839   6.95   CYTOPLASM
Betaine-homocysteine methyltransferase    NP_001704   BHMT 1   1   44970   6.40   CYTOPLASM
Calbindin 1   NP_004920   CALB1 2   6   30025   4.70   CYTOPLASM
Carbonic anhydrase II   NP_000058   CA2 3   4   29246   6.87   CYTOPLASM
Cytosolic malate dehydrogenase   NP_005908   MDH1 2   3   36426   6.91   CYTOPLASM
D-dopachrome tautomerase    NP_001346   DDT 1   1   12712   6.72   CYTOPLASM
Dicarbonyl/L-xylulose reductase   NP_057370   DCXR 1   1   25913   8.33   CYTOPLASM
Dimethylarginine dimethylaminohydrolase 1   NP_036269   DDAH1 1   4   31122   5.53   CYTOPLASM
Enolase 1   NP_001419   ENO1 8   34   47169   7.01   CYTOPLASM
Eukaryotic translation elongation factor 1 alpha 1   NP_001393   EEF1A1 1   35   50141   9.10   CYTOPLASM
Eukaryotic translation initiation factor 4H   NP_071496   WBSCR1 1   1   27385   6.67   CYTOPLASM
Eukaryotic translation initiation factor 5A   NP_001961   EIF5A 1   4   16832   5.07   CYTOPLASM
Fatty acid binding protein 3   NP_004093   FABP3 1   1   14858   6.29   CYTOPLASM
Ferritin, light polypeptide   NP_000137   FTL 1   6   20020   5.51   CYTOPLASM
Gamma-butyrobetaine hydroxylase   NP_003977   BBOX1 1   1   44715   6.28   CYTOPLASM
Glucose phosphate isomerase   NP_000166   GPI 1   1   63147   8.42   CYTOPLASM
Glutathione S-transferase A1   NP_665683   GSTA1 3   11   25631   8.91   CYTOPLASM
Glutathione S-transferase A2   NP_000837   GSTA2 3   11   25678   8.51   CYTOPLASM
Glutathione S-transferase A3   NP_000838   GSTA3 3   11   25302   9.21   CYTOPLASM
Glutathione S-transferase M3   NP_000840   GSTM3 2   5   26560   5.37   CYTOPLASM
Glutathione transferase   NP_000843   GSTP1 3   15   23356   5.43   CYTOPLASM
Glyceraldehyde-3-phosphate dehydrogenase    NP_002037   GAPDH 4   25   36053   8.57   CYTOPLASM
Heat shock 70 kDa protein 1A   NP_005336   HSPA1A 4   7   70038   5.48   CYTOPLASM
Heat shock 70 kDa protein 1B   NP_005337   HSPA1B 4   7   70025   5.48   CYTOPLASM
Heat shock 70kDa protein 6 (HSP70B')   NP_002146   HSPA6 2   17   71028   5.81   CYTOPLASM
Heat shock 70kDa protein 8   NP_006588   HSPA8 12   57   70898   5.37   CYTOPLASM
Heat shock 90kDa protein 1, beta   NP_031381   HSP90AB1 3   11   83264   4.97   CYTOPLASM
Heat shock protein 90kDa alpha (cytosolic), class A member 1   NP_001017963   HSP90AA1 2   2   84674   4.94   CYTOPLASM
Heat-responsive protein 12   NP_005827   HRSP12 2   4   14494   8.73   CYTOPLASM
Heme binding protein 1   NP_057071   HEBP1 1   2   21097   5.71   CYTOPLASM
Hemoglobin         1   2           CYTOPLASM
Hydroxyprostaglandin dehydrogenase 15-(NAD)   NP_000851   HPGD 1   1   28977   5.56   CYTOPLASM
Isocitrate dehydrogenase 1 (NADP+), soluble   NP_005887   IDH1 3   9   46659   6.53   CYTOPLASM
Lactate dehydrogenase A   NP_005557   LDHA 3   13   36689   8.44   CYTOPLASM
Lactate dehydrogenase B   NP_002291   LDHB 5   12   36638   5.71   CYTOPLASM
Mob4B protein   NP_060691   MOBK1B 1   1   25008   6.71   CYTOPLASM
NADP-dependent leukotriene B4 12-hydroxydehydrogenase    NP_036344   LTB4DH 1   1   35886   8.45   CYTOPLASM
Napsin A preproprotein   NP_004842   NAPSA 3   16   45387   6.15   CYTOPLASM
Peptidylprolyl isomerase A    NP_066953   PPIA 5   20   18012   7.68   CYTOPLASM
Peroxiredoxin 2   NP_005800   PRDX2 1   1   21892   5.66   CYTOPLASM
Peroxiredoxin 6   NP_004896   PRDX6 1   3   25035   6.00   CYTOPLASM
Phosphoglycerate kinase 1    NP_000282   PGK1 2   5   44615   8.30   CYTOPLASM
Phosphoglycerate mutase 1 (brain)   NP_002620   PGAM1 2   2   28804   6.67   CYTOPLASM
Prostatic binding protein   NP_002558   PEBP1 6   23   21057   7.01   CYTOPLASM
Proteasome beta 3 subunit   NP_002786   PSMB3 1   1   22949   6.14   CYTOPLASM
Pyruvate kinase 3   NP_002645   PKM2 2   2   57937   7.96   CYTOPLASM
Retinol binding protein 5, cellular   NP_113679   RBP5 1   1   15931   6.09   CYTOPLASM
RNA binding motif protein 3   NP_006734   RBM3 1   6   17170   8.86   CYTOPLASM
S100 calcium binding protein A16    NP_525127   S100A16 1   1   11801   6.28   CYTOPLASM
S100 calcium binding protein P   NP_005971   S100P 2   3   10400   4.75   CYTOPLASM
Stratifin    NP_006133   SFN 3   18   27774   4.68   CYTOPLASM
Superoxide dismutase 1, soluble   NP_000445   SOD1 1   1   15936   5.70   CYTOPLASM
Synuclein, gamma (breast cancer-specific protein 1)   NP_003078   SNCG 1   1   13301   4.97   CYTOPLASM
Triosephosphate isomerase 1    NP_000356   TPI1 5   18   26669   6.45   CYTOPLASM
Tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide   NP_006752   YWHAE 3   6   29174   4.63   CYTOPLASM
Tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide   NP_006817   YWHAQ 1   2   27764   4.68   CYTOPLASM
Tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide   NP_003397   YWHAZ 5   12   27745   4.73   CYTOPLASM
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide   NP_003395   YWHAB 3   4   28082   4.76   CYTOPLASM
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide   NP_036611   YWHAG 1   1   28374   4.66   CYTOPLASM
Angiotensin I converting enzyme isoform 1 precursor   NP_000780   ACE 9   12   149715   5.95   PLASMA MEMBRANE
Aquaporin 1   NP_932766   AQP1 2   9   28526   6.95   PLASMA MEMBRANE
Aquaporin 2   NP_000477   AQP2 2   2   28838   6.44   PLASMA MEMBRANE
ATP-binding cassette sub-family B member 1   NP_000918   ABCB1 1   1   141479   9.06   PLASMA MEMBRANE
Bone marrow stromal cell antigen 2   NP_004326   BST2 1   3   19769   5.43   PLASMA MEMBRANE
CD9 antigen   NP_001760   CD9 4   101   25416   6.80   PLASMA MEMBRANE
CD63 antigen   NP_001771   CD63 1   19   25637   8.14   PLASMA MEMBRANE
CD81 antigen   NP_004347   CD81 3   23   25809   5.09   PLASMA MEMBRANE
Chloride intracellular channel 1   NP_001279   CLIC1 2   11   26923   5.09   PLASMA MEMBRANE
Complement receptor 1 isoform S precursor   NP_000564   CR1 1   2   272873   6.60   PLASMA MEMBRANE
CTL2 protein   NP_065161   SLC44A2 5   16   80136   8.93   PLASMA MEMBRANE
Dipeptidylpeptidase IV   NP_001926   DPP4 9   82   88279   5.67   PLASMA MEMBRANE
Epidermal growth factor (beta-urogastrone)   NP_001954   EGF 12   56   133946   5.56   PLASMA MEMBRANE
Flotillin 1    NP_005794   FLOT1 1   1   47355   7.08   PLASMA MEMBRANE
FXYD domain-containing ion transport regulator 2    NP_001671   FXYD2 1   2   7283   7.88   PLASMA MEMBRANE
G protein-coupled receptor, family C, group 5, member A   NP_003970   GPRC5A 1   4   40251   8.39   PLASMA MEMBRANE
G protein-coupled receptor, family C, group 5, member B   NP_057319   GPRC5B 2   4   44795   8.56   PLASMA MEMBRANE
G protein-coupled receptor, family C, group 5, member C   NP_071319   GPRC5C 5   48   48193   8.72   PLASMA MEMBRANE
Gamma-glutamyltransferase 1 precursor   NP_005256   GGT1 8   81           PLASMA MEMBRANE
Glutamyl aminopeptidase (aminopeptidase A)   NP_001968   ENPEP 3   7   109272   5.34   PLASMA MEMBRANE
Integral membrane protein 2B   NP_068839   ITM2B 1   1   30338   5.00   PLASMA MEMBRANE
Low density lipoprotein-related protein 2   NP_004516   LRP2 36   113   521931   4.89   PLASMA MEMBRANE
Lysosomal-associated membrane protein 1    NP_005552   LAMP1 1   9   44773   9.22   PLASMA MEMBRANE
Major histocompatibility complex, class I, A precursor   NP_002107   HLA-A 1   2   40841   5.66   PLASMA MEMBRANE
Maltase-glucoamylase   NP_004659   MGAM 7   16   209703   5.26   PLASMA MEMBRANE
Membrane alanine aminopeptidase precursor   NP_001141   ANPEP 32   222   109512   5.27   PLASMA MEMBRANE
Membrane metallo-endopeptidase   NP_000893   MME 9   25   85738   5.84   PLASMA MEMBRANE
MUC1 mucin isoform 1 precursor   NP_002447   MUC1 6   396   29565   5.84   PLASMA MEMBRANE
NG22 protein   NP_079533   SLC44A4 4   32   79429   8.91   PLASMA MEMBRANE
PDZK1 interacting protein 1   NP_005755   PDZK1IP1 1   3   12227   4.79   PLASMA MEMBRANE
Phospholipid scramblase 1   NP_066928   PLSCR1 3   5   35049   4.83   PLASMA MEMBRANE
Podocalyxin-like precursor    NP_001018121   PODXL 5   33   55386   5.36   PLASMA MEMBRANE
Podocin   NP_055440   NPHS2 1   1   42201   8.95   PLASMA MEMBRANE
Polycystin 1 precursor    NP_001009944   PKD1 1   1   462417   6.28   PLASMA MEMBRANE
Polymeric immunoglobulin receptor   NP_002635   PIGR 7   25   83284   5.59   PLASMA MEMBRANE
Prominin 1   NP_006008   PROM1 11   67   97202   6.97   PLASMA MEMBRANE
Protein tyrosine phosphatase, receptor type, J precursor   NP_002834   PTPRJ 2   2   145927   5.37   PLASMA MEMBRANE
Purinergic receptor P2X4 isoform a   NP_002551   P2RX4 1   1   43369   8.29   PLASMA MEMBRANE
Rhesus blood group, C glycoprotein   NP_057405   RHCG 2   4   53179   5.93   PLASMA MEMBRANE
Sodium potassium chloride cotransporter 2   NP_000329   SLC12A1 3   10   121341   7.20   PLASMA MEMBRANE
Solute carrier family 1, member 1   NP_004161   SLC1A1 1   1   57086   5.56   PLASMA MEMBRANE
Solute carrier family 12 (sodium/chloride transporters), member 3   NP_000330   SLC12A3 4   4   113936   8.23   PLASMA MEMBRANE
Solute carrier family 2 (facilitated glucose/fructose transporter), member 5   NP_003030   SLC2A5 1   5   54974   5.81   PLASMA MEMBRANE
Stomatin isoform a   NP_004090   STOM 6   21   31731   7.71   PLASMA MEMBRANE
Tetraspan 1   NP_005718   TSPAN1 2   28   26301   5.12   PLASMA MEMBRANE
Transmembrane 7 superfamily member 3   NP_057635   TM7SF3 1   3   64166   6.56   PLASMA MEMBRANE
Transmembrane protease, serine 2   NP_005647   TMPRSS2 2   13   53891   8.12   PLASMA MEMBRANE
Tweety 3   NP_079526   TTYH3 1   1   126733   8.18   PLASMA MEMBRANE
Uroplakin 1A   NP_008931   UPK1A 1   2   28879   5.16   PLASMA MEMBRANE
Uroplakin 2   NP_006751   UPK2 2   8   19438   10.41   PLASMA MEMBRANE
Acid sphingomyelinase-like phosphodiesterase 3B    NP_055289   SMPDL3B 1   3   51910   5.34   EXTRACELLULAR (SECRETED)
Albumin precursor   NP_000468   ALB 19   130   69367   5.92   EXTRACELLULAR (SECRETED)
Alpha amylase       AMY 1   1           EXTRACELLULAR (SECRETED)
Alpha-1-microglobulin/bikunin precursor   NP_001624   AMBP 1   4   38999   5.95   EXTRACELLULAR (SECRETED)
Apolipoprotein D precursor    NP_001638   APOD 3   20   21276   5.06   EXTRACELLULAR (SECRETED)
Clusterin   NP_001822   CLU 3   8   52495   5.89   EXTRACELLULAR (SECRETED)
Collagen, type VI, alpha 1 precursor   NP_001839   COL6A1 1   1   108521   5.29   EXTRACELLULAR (SECRETED)
Complement component 3 precursor   NP_000055   C3 1   2   187164   6.02   EXTRACELLULAR (SECRETED)
Defensin, alpha 1 preproprotein   NP_004075   DEFA1 1   1   10201   6.54   EXTRACELLULAR (SECRETED)
Defensin, alpha 3 preproprotein   NP_005208   DEFA3 1   1   10245   5.71   EXTRACELLULAR (SECRETED)
Fibrinogen, alpha chain isoform alpha-E preproprotein    NP_000499   FGA 3   3   94973   5.70   EXTRACELLULAR (SECRETED)
Fibronectin 1   NP_997647   FN1 1   1   259226   5.49   EXTRACELLULAR (SECRETED)
Galectin 3 binding protein   NP_005558   LGALS3BP 10   155   65331   5.13   EXTRACELLULAR (SECRETED)
Ig alpha-1 chain C region         4   36           EXTRACELLULAR (SECRETED)
Ig alpha-2 chain C region         3   36           EXTRACELLULAR (SECRETED)
Ig gamma-1 chain C region         7   32           EXTRACELLULAR (SECRETED)
Ig gamma-2 chain C region         3   28           EXTRACELLULAR (SECRETED)
Ig heavy chain V region         5   33           EXTRACELLULAR (SECRETED)
Ig kappa chain C region         6   207           EXTRACELLULAR (SECRETED)
Ig lambda chain C region         4   37           EXTRACELLULAR (SECRETED)
Ig mu chain C region         2   9           EXTRACELLULAR (SECRETED)
Kininogen 1   NP_000884   KNG1 3   14   47883   6.29   EXTRACELLULAR (SECRETED)
Macrophage migration inhibitory factor (glycosylation-inhibiting factor)   NP_002406   MIF 1   1   12476   7.73   EXTRACELLULAR (SECRETED)
Mannan-binding lectin serine protease 2   NP_006601   MASP2 5   174   75702   5.39   EXTRACELLULAR (SECRETED)
Multimerin 2   NP_079032   MMRN2 1   4   104417   5.50   EXTRACELLULAR (SECRETED)
Prostatic acid phosphatase precursor    NP_001090   ACPP 3   4   44566   5.83   EXTRACELLULAR (SECRETED)
Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1   NP_000286   SERPINA1 2   5   46723   5.36   EXTRACELLULAR (SECRETED)
Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5   NP_000615   SERPINA5 8   61   45702   9.30   EXTRACELLULAR (SECRETED)
Serpin peptidase inhibitor, clade A, member 3 precursor   NP_001076   SERPINA3 4   13   48637   5.79   EXTRACELLULAR (SECRETED)
Serum amyloid P component precursor   NP_001630   APCS 3   6   25387   6.10   EXTRACELLULAR (SECRETED)
Thrombospondin 1 precursor    NP_003237   THBS1 1   1   129383   4.71   EXTRACELLULAR (SECRETED)
Transferrin    NP_001054   TF 1   2   77050   6.81   EXTRACELLULAR (SECRETED)
Vitronectin precursor   NP_000629   VTN 1   1   54336   5.55   EXTRACELLULAR (SECRETED)
2',3'-cyclic nucleotide 3' phosphodiesterase   NP_149124   CNP 1   1   45099   8.73   PLASMA MEMBRANE (PERIPHERAL)
Arrestin domain containing 1   NP_689498   ARRDC1 2   4   45981   6.53   PLASMA MEMBRANE (PERIPHERAL)
BAI1-associated protein 2   NP_059344   BAIAP2 2   4   57359   8.96   PLASMA MEMBRANE (PERIPHERAL)
BAI1-associated protein 2-like 1   NP_061330   BAIAP2L1 1   9   56883   8.82   PLASMA MEMBRANE (PERIPHERAL)
Cubilin   NP_001072   CUBN 43   147   398997   5.15   PLASMA MEMBRANE (PERIPHERAL)
Epidermal growth factor receptor pathway substrate 8    NP_004438   EPS8 1   3   91910   7.10   PLASMA MEMBRANE (PERIPHERAL)
G-protein gamma-12 subunit   NP_061329   GNG12 5   18   8006   9.14   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide binding protein (G protein), alpha 11 (Gq class)   NP_002058   GNA11 4   9   42163   5.52   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1   NP_002060   GNAI1 5   25   40361   5.69   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2   NP_002061   GNAI2 3   6   40451   5.34   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3   NP_006487   GNAI3 2   6   40532   5.50   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1   NP_000507   GNAS 6   15   45665   5.59   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide binding protein (G protein), gamma 7   NP_443079   GNG7 1   1   7522   8.71   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide-binding protein, beta-1 subunit   NP_002065   GNB1 5   28   37377   5.60   PLASMA MEMBRANE (PERIPHERAL)
Guanine nucleotide-binding protein, beta-2 subunit   NP_005264   GNB2 3   12   37331   5.60   PLASMA MEMBRANE (PERIPHERAL)
Moesin   NP_002435   MSN 5   30   67820   6.08   PLASMA MEMBRANE (PERIPHERAL)
Protein-tyrosine kinase FYN or LCK or YES or SRC       FYN, LCK, YES1, SRC 1   2           PLASMA MEMBRANE (PERIPHERAL)
Radixin   NP_002897   RDX 3   27   68564   6.03   PLASMA MEMBRANE (PERIPHERAL)
Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1   NP_004243   SLC9A3R1 2   2   38868   5.55   PLASMA MEMBRANE (PERIPHERAL)
Syntenin   NP_005616   SDCBP 12   139   32417   7.06   PLASMA MEMBRANE (PERIPHERAL)
Villin 2   NP_003370   VIL2 8   40   69413   5.94   PLASMA MEMBRANE (PERIPHERAL)
Calcium binding protein 39   NP_057373   CAB39 2   4   39869   6.43   UNCLASSIFIED
Chromosome 9 open reading frame 19   NP_071738   C9orf19 2   2   17218   9.44   UNCLASSIFIED
Fc fragment of IgG binding protein   NP_003881   FCGBP 1   4   572096   5.14   UNCLASSIFIED
Hypothetical protein LOC51534   NP_057569   C6orf55 4   13   33879   5.87   UNCLASSIFIED
Hypothetical protein LOC55004   NP_060377   C11orf59 1   1   17745   5.01   UNCLASSIFIED
Hypothetical protein LOC93343   NP_612410   LOC93343 2   10   28783   9.10   UNCLASSIFIED
Matrix-remodelling associated 8   NP_115724   MXRA8 2   4   49132   6.75   UNCLASSIFIED
Olfactomedin 4 precursor   NP_006409   OLFM4 10   72   57280   5.50   UNCLASSIFIED
PP1201 protein    NP_071435   TMBIM1 1   2   34623   7.60   UNCLASSIFIED
Putative MAPK activating protein PM28   NP_055576   KIAA0174 8   96   39928   7.65   UNCLASSIFIED
Unc-51-like kinase 3   NP_056333   ULK3 1   1   24402   8.63   UNCLASSIFIED
Actin related protein 2/3 complex subunit 4   NP_005709   ARPC4 2   2   19667   8.53   CYTOPLASM (CYTOSKELETAL)
Actin: alpha, alpha2, beta, gamma1, gamma2       ACTA1, ACTA2, ACTB, ACTC, ACTG1, ACTG2 12   81           CYTOPLASM (CYTOSKELETAL)
Cofilin 1 (non-muscle)    NP_005498   CFL1 5   14   18502   8.22   CYTOPLASM (CYTOSKELETAL)
Destrin   NP_006861   DSTN 2   3   18506   8.06   CYTOPLASM (CYTOSKELETAL)
Dynein, axonemal, heavy polypeptide 8   NP_001362   DNAH8 1   1   514814   5.95   CYTOPLASM (CYTOSKELETAL)
Myosin, heavy polypeptide 9, non-muscle    NP_002464   MYH9 1   1   81804   7.55   CYTOPLASM (CYTOSKELETAL)
Profilin 1   NP_005013   PFN1 3   8   15054   8.44   CYTOPLASM (CYTOSKELETAL)
Profilin 2    NP_444252   PFN2 1   2   15046   6.55   CYTOPLASM (CYTOSKELETAL)
Tubulin, beta 2   NP_001060   TUBB2A 1   1   49907   4.78   CYTOPLASM (CYTOSKELETAL)
Acid alpha-glucosidase preproprotein   NP_000143   GAA 1   2   105338   5.62   LYSOSOME
Alpha-N-acetylglucosaminidase precursor   NP_000254   NAGLU 1   1   82167   6.10   LYSOSOME
Galactosidase, beta 1    NP_000395   GLB1 9   69   76091   6.10   LYSOSOME
Glucuronidase, beta    NP_000172   GUSB 1   1   74716   6.54   LYSOSOME
Lysosomal acid phosphatase 2 precursor    NP_001601   ACP2 2   5   48344   6.28   LYSOSOME
N-acylsphingosine amidohydrolase (acid ceramidase) 1 preproprotein    NP_808592   ASAH1 1   1   44650   7.52   LYSOSOME
Prosaposin    NP_002769   PSAP 1   1   58113   5.06   LYSOSOME
Protective protein for beta-galactosidase   NP_000299   PPGB 3   21   54496   6.16   LYSOSOME
Tripeptidyl-peptidase I precursor   NP_000382   TPP1 4   11   61248   6.01   LYSOSOME
Vacuolar H+ ATPase C2   NP_001034451   ATP6V1C2 1   1   43866   5.72   LYSOSOME
Carbonic anhydrase IV precursor   NP_000708   CA4 2   5   35032   7.68   PLASMA MEMBRANE (GPI-LINKED)
CD59 antigen p18-20    NP_000602   CD59 5   45   14177   6.02   PLASMA MEMBRANE (GPI-LINKED)
Dipeptidase 1 (renal)    NP_004404   DPEP1 10   56   45674   5.75   PLASMA MEMBRANE (GPI-LINKED)
Prostate stem cell antigen preproprotein   NP_005663   PSCA 3   33   12912   5.07   PLASMA MEMBRANE (GPI-LINKED)
Ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)   NP_002925   RNASE2 1   1   18354   9.10   PLASMA MEMBRANE (GPI-LINKED)
Thy-1 cell surface antigen   NP_006279   THY1 1   7   17935   8.96   PLASMA MEMBRANE (GPI-LINKED)
Uromodulin precursor   NP_003352   UMOD 19   2481   69739   4.97   PLASMA MEMBRANE (GPI-LINKED)
X-prolyl aminopeptidase 2, membrane-bound   NP_003390   XPNPEP2 2   3   75667   5.69   PLASMA MEMBRANE (GPI-LINKED)
Fusion (involved in t(12;16) in malignant liposarcoma)   NP_004951   FUS 1   7   53426   9.40   NUCLEUS
Histone H4   NP_778224   HIST4H4 2   3   11237   11.20   NUCLEUS
Non-POU domain containing, octamer-binding   NP_031389   NONO 1   16   54232   9.01   NUCLEUS
Nuclear transport factor 2   NP_005787   NUTF2 1   1   14478   5.10   NUCLEUS
Nucleophosmin 1   NP_002511   NPM1 1   12   32575   4.64   NUCLEUS
Polypyrimidine tract-binding protein 1   NP_002810   PTBP1 1   7   59633   9.21   NUCLEUS
Putative nuclear protein ORF1-FL49    NP_115788   ORF1-FL49 1   8   10631   4.20   NUCLEUS
Small nuclear ribonucleoprotein D1 polypeptide 16kDa   NP_008869   SNRPD1 1   6   13282   11.56   NUCLEUS
Calreticulin precursor   NP_004334   CALR 1   1   48142   4.29   ER/GOLGI
Golgi apparatus protein 1   NP_036333   GLG1 2   5   134360   6.65   ER/GOLGI
Heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)   NP_005338   HSPA5 1   1   72333   5.07   ER/GOLGI
Lectin, mannose-binding 2   NP_006807   LMAN2 5   28   40229   6.46   ER/GOLGI
Mannosidase, alpha, class 1A, member 1   NP_005898   MAN1A1 4   8   72969   6.04   ER/GOLGI
Prolyl 4-hydroxylase, beta subunit   NP_000909   P4HB 1   6   57116   4.76   ER/GOLGI
Chaperonin   NP_002147   HSPD1 1   1   61055   5.70   MITOCHONDRIA
Sorting and assembly machinery component 50 homolog   NP_056195   SAMM50 1   1   51962   6.44   MITOCHONDRIA

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