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Document Number | 1450 |
|---|---|
Primary Title | Isolation and Characterization of a Pleiotropic Glucose Repression Resistant Mutant of Saccharomyces cerevisiae |
Author Name | Bailey, R. B.;Woodword, A. |
Author Affiliation | Solar Energy Research Inst., Golden, CO |
Published Date | 01/01/1984 |
Detailed Publish Date | 1984 |
Title Source | Molecular & General Genetics |
Volume Number | 193 |
Issue Number | 3 |
Page Range | 507-512 |
Page Count | 6 |
Document Type | JOURNAL ARTICLE |
Abstract | A new mutation has been described which confers resistance to catabolite repression in S. cerevisiae. The mutant allele, termed grr-1 for glucose repression-resistant, is characterized by insensitivity to glucose repression for the cytoplasmic enzymes invertase, maltase, and galactokinase, as well as the mitochondrial enzyme cytochrome c oxidase. Hexokinase levels in grr-1 mutants are .apprx.3-fold higher than the corresponding activity of the parental strain. Although the grr-1 allele is expressed phenotypically similarly to the hex-1 and hex-2 mutations, it represents a new class of mutation. |
ISBN ISSN | 0026-8925 |
Copyright Status | Y - Copyrighted--no reprint permission, |
Document Owner | B |