Retrospective Study Evaluating IGF1R And p95HER2 as Prognostic Factors in Non Small Cell Lung Cancer (NSCLC) - Full Text View

Sponsored by:	Istituto Clinico Humanitas
Information provided by:	Istituto Clinico Humanitas
ClinicalTrials.gov Identifier:	NCT00763607

Purpose

Aim of the study is to evaluated the role of IGF1R and p95HER2 on prognosis in radically resected non small cell lung cancer patients

The primary objective is to correlate the expression of IGF1R and p95HER2 with survival.

Condition	Intervention
Non Small Cell Lung Cancer	Genetic: Protein expression by immunoistochemistry and immunofluorescence

MedlinePlus related topics: Cancer Lung Cancer

Study Type:	Observational
Study Design:	Cohort, Retrospective
Official Title:	Retrospective Study Evaluating IGF1R And p95HER2 as Prognostic Factors in Radically Resected Non Small Cell Lung Cancer

Further study details as provided by Istituto Clinico Humanitas:

Primary Outcome Measures:

Association of different biomarkers with survival [ Time Frame: At the end of enrollment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Association of a specific biomarker with patient's characteristics [ Time Frame: At the end of enrollment ] [ Designated as safety issue: No ]

Biospecimen Retention: Samples With DNA

Biospecimen Description:

Paraffine embedded tumor sections

Enrollment:	454
Study Start Date:	November 2007
Estimated Study Completion Date:	December 2008
Primary Completion Date:	February 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
1 Radically resected Non small cell lung cancer patients in stage I-III	Genetic: Protein expression by immunoistochemistry and immunofluorescence Protein expression by immunoistochemistry and immunofluorescence

Eligibility

Study Population

Radically resected non small cell lung cancer patients

Criteria

Inclusion Criteria:

Radically resected non small cell lung cancer patients with tumor tissue available

Exclusion Criteria:

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00763607

Locations

Sponsors and Collaborators

Istituto Clinico Humanitas

Investigators

Principal Investigator:

Armando Santoro, MD

Istituto Clinico Humanitas

More Information

Responsible Party:	Istituto Clinico Humanitas ( Armando Santoro, MD )
Study ID Numbers:	ONC/OSS-02/2007
Study First Received:	September 30, 2008
Last Updated:	September 30, 2008
ClinicalTrials.gov Identifier:	NCT00763607
Health Authority:	Italy: Ministry of Health

Keywords provided by Istituto Clinico Humanitas:

non small cell lung cancer patients

Study placed in the following topic categories:

Thoracic Neoplasms
Non-small cell lung cancer
Respiratory Tract Diseases
Lung Neoplasms

Lung Diseases
Carcinoma, Non-Small-Cell Lung
Neoplasms, Glandular and Epithelial
Carcinoma

Additional relevant MeSH terms:

Respiratory Tract Neoplasms
Neoplasms
Neoplasms by Site
Neoplasms by Histologic Type

ClinicalTrials.gov processed this record on February 09, 2009