From ntpmail at list.niehs.nih.gov Tue Jan 10 17:31:42 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Jan 11 08:26:26 2006 Subject: NTP UPDATE: (no subject) Message-ID: <43C435CE.E44C2333@niehs.nih.gov> Dr. Christopher Portier named Associate Director for Risk Assessment at the National Institute of Environmental Health Sciences. Press Release attached. -------------- next part -------------- A non-text attachment was scrubbed... Name: PressRelease.pdf Type: application/pdf Size: 104364 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060110/9b58409e/PressRelease.pdf From ntpmail at list.niehs.nih.gov Mon Jan 23 14:48:50 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jan 23 14:48:54 2006 Subject: NTP UPDATE: Quarterly Issue Available Message-ID: <43D53322.97DA6D0F@niehs.nih.gov> The quarterly issue of the NTP Update is now available on the NTP website at http://ntp.niehs.nih.gov (see Latest News). Highlights ? Christopher J. Portier, Ph.D., named Associate Director for Risk Assessment. ? NTP and High Throughput Screening ? New NIEHS website: Genetic Alterations in Cancer (GAC) knowledge system is now available at https://dir-apps.niehs.nih.gov/gac. ? The NTP will be at booths 337 & 339 at the 45th Annual Society of Toxicology Meeting in San Diego, CA during the week of March 5-9, 2006. Meetings ? NTP Board of Scientific Counselors Nanotechnology Working Group (NWG) will meet on March 15, 2006, at the Holiday Inn-Rosslyn at Key Bridge in Arlington, VA. ? The NTP Technical Reports Review Subcommittee will meet on June 12, 2006, at the NIEHS, Research Triangle Park, NC. Workshops ? A workshop, Hormonally Induced Reproductive Tumors: Relevance of Rodent Bioassays is scheduled for May 22-24, 2006, at the Marriott Raleigh Crabtree Valley in Raleigh, NC. NTP Centers ? CERHR: (1) expert panel report on DEHP is now available for public comment through February 3, 2006 and can be found at http://cerhr.niehs.nih.gov/, (2) expert panel meeting on genistein and soy formula is scheduled for March 15-17, 2006 at the Radisson Hotel Old Town in Alexandria, VA. ? NICEATM and ICCVAM: the second expert panel report on the evaluation of the current validation status for In Vitro test methods for identifying ocular corrosives and severe irritants is available at http://cerhr.niehs.nih.gov/. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060123/527babe1/attachment.htm From ntpmail at list.niehs.nih.gov Mon Jan 30 17:20:41 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jan 30 17:20:54 2006 Subject: NTP UPDATE: Botulinum Toxin Potency Testing Message-ID: <43DE9139.8FFF6295@niehs.nih.gov> Alternative Methods to the Mouse LD50 Assay for Botulinum Toxin Potency Testing A request for comments, nominations of experts, and submission of data for a proposed workshop on alternative methods to replace the Mouse LD50 Assay for Botulinum Toxin Potency Testing was announced in the Federal Register on January 27, 2006 (Vol. 71, No. 18, pp. 4603-4). The FR notice can be found at: http://iccvam.niehs.nih.gov/docs/FR/7104603.pdf in PDF or http://iccvam.niehs.nih.gov/docs/FR/7104603.htm in HTML. This notice is in response to a nomination made to NICEATM by the Humane Society of the United States (HSUS) in October 2005. The HSUS nomination is available on the "Nominations and Submissions" page at http://iccvam.niehs.nih.gov/nomsub/submission.htm. Please send public comment, nominations and data submissions by COB, March 13, 2006, to: email: niceatm@niehs.nih.gov fax: 919-541-0947, or mail to: Dr. William S. Stokes, Director NICEATM, NIEHS 79 T.W. Alexander Drive PO Box 12233, MD EC-17 Research Triangle Park, NC 27709 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060130/45a2edcf/attachment.htm From ntpmail at list.niehs.nih.gov Tue Feb 7 14:25:36 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Feb 7 14:25:41 2006 Subject: NTP UPDATE: TestSmart DNT Symposium Announcement Message-ID: <43E8F430.5D6D373B@niehs.nih.gov> The NTP is co-sponsoring a TestSmart DNT symposium: ?Creating a Humane and Efficient Approach to Developmental Neurotoxicity Testing.? This symposium is the first of a series that will bring together leading stakeholders from around the world to develop the Developmental Neurotoxicity (DNT) testing methods of the future. The symposium is presented by the Johns Hopkins Center for Alternatives to Animal Testing (CAAT) and will be held on March 13-15, 2006 at the Hyatt Regency Reston, Reston, VA. Information about the meeting, including a pdf version of the event brochure, is available at http://caat.jhsph.edu/dnt/. From ntpmail at list.niehs.nih.gov Thu Feb 23 12:54:20 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Feb 23 12:54:26 2006 Subject: NTP UPDATE: NTP to Exhibit at SOT in San Diego Message-ID: <43FDF6CC.42B4699C@niehs.nih.gov> The NTP invites everyone attending the Society of Toxicology 45th Annual Meeting and ToxExpo, March 5-9 in San Diego, CA to stop by booth #337 for a visit. The attached PDF file contains a list of NTP talks and posters being presented at the SOT meeting. -------------- next part -------------- A non-text attachment was scrubbed... Name: SOTNTP.pdf Type: application/pdf Size: 285759 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060223/59e0db27/SOTNTP.pdf From ntpmail at list.niehs.nih.gov Mon Mar 20 15:20:35 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Mar 20 15:23:34 2006 Subject: NTP UPDATE: ICCVAM May 2003 Endocrine Disruptor Report Addendum Now Available Message-ID: <441F0E93.5E4FE91D@niehs.nih.gov> The availability of an Addendum to the "ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential Endocrine Disruptors: ER and AR Binding and Transcriptional Activation Assays." (NIH Publication No. 03-4503, May 2003), was announced in the Federal Register (Vol. 71, No. 51, pp. 13597-8) on March 16, 2006. The Addendum is available at http://iccvam.niehs.nih.gov/methods/endodocs/EDAddendum.pdf. The May 2003 report can be accessed at http://iccvam.niehs.nih.gov/methods/endodocs/edfinrpt/edreport.htm. A copy of the FR notice can be found at: http://iccvam.niehs.nih.gov/docs/FR/7113597.pdf in PDF or http://iccvam.niehs.nih.gov/docs/FR/7113597.htm in HTML. NICEATM invites public comment on the addendum and submission of in vivo and in vitro data. Written comments and data should be received by Monday, May 1, 2006. email: niceatm@niehs.nih.gov fax: 919-541-0947 mail to: Dr. Raymond Tice NICEATM, NIEHS 79 T.W. Alexander Drive PO Box 12233 MD EC-17 Research Triangle Park, NC 27709 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060320/bee390fc/attachment.htm From ntpmail at list.niehs.nih.gov Tue Apr 11 11:36:52 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Apr 11 11:37:18 2006 Subject: NTP UPDATE: Office of Chemical Nomination & Selection announces nominations Message-ID: National Toxicology Program (NTP) Office of Chemical Nomination and Selection announcement of and request for comments on toxicological study nominations to the NTP Information on nominations and Federal Register Notice available at: http://ntp.niehs.nih.gov/go/21134 From ntpmail at list.niehs.nih.gov Wed Apr 19 16:03:52 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Apr 19 16:04:18 2006 Subject: NTP UPDATE: Quarterly "Update" now available Message-ID: The quarterly issue of the NTP Update is now available on the NTP website at http://ntp.niehs.nih.gov under "Latest News." Highlights include: * Dr. Allen Dearry Assumes Post as Interim Associate Director of the NTP * NTP Receives Awards at Society of Toxicology (SOT) Annual Meeting in March * NTP to sponsor a pathology satellite symposium at the Annual Society of Toxicologic Pathology on June 17 * NTP workshop, "Hormonally Induced Reproductive Tumors: Relevance of Rodent Bioassays," is scheduled for May 22-24, 2006 * NTP Board of Scientific Counselors will meet on June 13 at the NIEHS. * NTP Technical Reports Review Subcommittee is scheduled to convene on June 12 and on August 28. * Center for the Evaluation of Risks to Human Reproduction (CERHR) upcoming events and available monographs * The NTP Testing Program requests study nominations * NTP Interagency Center for the Evaluation of Alternative Toxicology Methods (NICEATM) news From ntpmail at list.niehs.nih.gov Thu Apr 20 09:13:29 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Apr 20 09:13:57 2006 Subject: NTP UPDATE: June 12 Board Meeting Announced Message-ID: The NTP Board of Scientific Counselors (BSC) meeting will be held on June 12, 2006 in the Rodbell Auditorium, Rall Building at the National Institute of Environmental Health Sciences, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709 at 8:30 a.m. and is open to the public. Individuals who plan to attend are encouraged to register online at the NTP website by May 31. Preliminary agenda topics include: * NIEHS Strategic Plan * Update of NTP Activities * NTP BSC's Technical Report Review Subcommittee Report * NTP Testing Nominations Further information, including Federal Register announcement and online registration are available on the NTP website meeting page: http://ntp.niehs.nih.gov/go/83 From ntpmail at list.niehs.nih.gov Thu Apr 20 14:19:01 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Apr 20 14:19:26 2006 Subject: NTP UPDATE: NTP Board Meeting Clarification Message-ID: This notice is to correct the previous announcement (June 12 Board Meeting announced) and clarify the upcoming NTP Board meetings. * The NTP Board of Scientific Counselors Technical Reports Review Subcommittee Meeting will be held on June 12, 2006 in the Rodbell Auditorium, Rall Building at the National Institute of Environmental Health Sciences, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709 at 8:30 a.m. and is open to the public. Draft reports tentatively scheduled for review: TR-539: Genistein (multigeneration) TR-540: Methylene blue trihydrate TR-543: alpha-Methylstyrene TR-545: Genistein (2 year) Further information about this meeting is available at http://ntp.niehs.nih.gov/go/15843 * On the following day, June 13, 2006, the NTP Board of Scientific Counselors (BSC) meeting will be held in the Rodbell Auditorium, Rall Building at the National Institute of Environmental Health Sciences, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709 at 8:30 a.m. and is open to the public. Individuals who plan to attend are encouraged to register online at the NTP website by May 31. Preliminary agenda topics include: * NIEHS Strategic Plan * Update of NTP Activities * NTP BSC's Technical Report Review Subcommittee Report * NTP Testing Nominations Further information, including Federal Register announcement and online registration are available on the NTP website meeting page: http://ntp.niehs.nih.gov/go/83 From ntpmail at list.niehs.nih.gov Mon May 1 13:30:03 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon May 1 13:30:29 2006 Subject: NTP UPDATE: NIEHS Strategic Plan Message-ID: NIEHS is very pleased to share with you the final version of the NIEHS Strategic Plan, entitled New Frontiers in Environmental Sciences and Human Health http://www.niehs.nih.gov/external/plan2006/home.htm. This plan reflects the important contributions made by people here at the Institute and in our extended community. This plan provides a framework that will allow NIEHS to make an even greater impact on human health. From ntpmail at list.niehs.nih.gov Tue May 16 14:34:25 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue May 16 14:34:49 2006 Subject: NTP UPDATE: Genistein & Soy Formula Reports Available Message-ID: The Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the availability of the Genistein & Soy Formula Expert Panel Reports and requests public comment. The reports are available on the CERHR website (http://cerhr.niehs.nih.gov). Written public comments on these reports should be received by July 5, 2006. You may provide input to the NTP at: http://ntp.niehs.nih.gov/go/27902 Federal Register Notice: http://ntp.niehs.nih.gov/index.cfm?objectid=3E5DDCE3-F1F6-975E-74498B3C6F249D24 From ntpmail at list.niehs.nih.gov Mon Jun 5 16:20:25 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jun 5 16:20:56 2006 Subject: NTP UPDATE: Di-(2-ethylhexyl) phthalate draft Brief available Message-ID: The Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the availability of the draft NTP Brief on Di-(2-ethylhexyl) phthalate (DEHP) and requests comments - http://ntp.niehs.nih.gov/index.cfm?objectid=A5CCCB11-F1F6-975E-76CD8D3A455C258B From ntpmail at list.niehs.nih.gov Wed Jun 7 17:52:09 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Jun 7 17:52:17 2006 Subject: NTP UPDATE: Videocast of NTP Board Meetings Available Message-ID: <44874A89.4FB4AB89@niehs.nih.gov> The Technical Reports Review Subcommittee meeting on June 12 and the Board of Scientific Counselors meeting on June 13 will begin at 8:30 am on both days. Videocast of this meeting is available at http://www.niehs.nih.gov/external/video.htm. From ntpmail at list.niehs.nih.gov Thu Jun 8 13:49:35 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Jun 8 13:49:34 2006 Subject: NTP UPDATE: Public Comment Invited on Draft Report Message-ID: <4488632F.8000804@niehs.nih.gov> The Secretary's Advisory Committee on Genetics, Health, and Society (SACGHS) seeks public input on the draft report, Policy Issues Associated with Undertaking a Large U.S. Population Cohort Project on Genes, Environment, and Disease. The public comment period on the draft report ends July 31, 2006. The draft report is available electronically at http://www4.od.nih.gov/oba/sacghs/public_comments.htm. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060608/9dfcc44f/attachment.htm From ntpmail at list.niehs.nih.gov Tue Jun 20 09:53:47 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Jun 20 09:54:17 2006 Subject: NTP UPDATE: Biomarkers Workshop Announcement & Request for Comments Message-ID: The NTP announces a workshop on Biomarkers for Toxicology Studies to be held on September 20-21, 2006 at the NIEHS in Research Triangle Park, NC. Additional information can be found on the meeting page link: http://ntp.niehs.nih.gov/go/20940 From ntpmail at list.niehs.nih.gov Mon Jun 26 07:18:59 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jun 26 07:19:30 2006 Subject: NTP UPDATE: Webcast Invitation: Secy's Advis Committee w/ Schwartz on Environmental Components of Gene-Environ Studies Message-ID: > Subject: Webcast Invitation: Secy's Advis Committee w/ Schwartz on Environmental Components of Gene-Environ Studies > > NIEHS Director Dr. David Schwartz will be giving a presentation entitled > "> Environmental Components of Gene-Environment Studies> "> on Monday, June 23, 2006 at 4:20 p.m. as part of the Large Population Studies Session of the Secretary's Advisory Committee on Genetics, Health, and Society. You are invited to access the live webcast of this meeting. Information on how to access the webcast will be available on the day of the meeting at > > Agenda > > June 26th will include a review of the Committee's draft report and recommendations on pharmacogenomics and a briefing on Food and Drug Administration's Critical Path Initiative. The Committee also will hear from the Centers for Medicare & Medicaid Services on the status of a proposal to add a genetics specialty to the regulations implementing the Clinical Laboratory Improvement Amendments. In addition, the Committee will discuss the status of its solicitation of public comments on the Committee's draft report "Policy Issues Associated with Undertaking a Large U.S. Population Cohort Project on Genes, Environment, and Disease" (posted at >) and, to further inform the draft report, the Committee will hear presentations on environmental components of gene-environment studies. > > June 27th will begin with several presentations intended to provide the Committee with a better understanding of the impact of gene patents and licensing practices on access to genetic tests and services and the role and economic impact of gene patents in drug and diagnostics development. These presentations will help inform the Committee's next steps on this issue. The Committee will also be updated about the status of Federal genetic non-discrimination legislation and the work of the two interagency work groups regarding the impact of direct-to-consumer marketing of genetic tests. > > An agenda has been posted online at > > > > > > From ntpmail at list.niehs.nih.gov Mon Jun 26 10:16:21 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jun 26 10:16:54 2006 Subject: NTP UPDATE: Webcast Invitation: Date Clarification Message-ID: Date Clarification: The webcast presentation is Monday June 26, 2006 rather than Monday, June 23 as stated in previous announcement. ************************************ > Subject: Webcast Invitation: Secy's Advis Committee w/ Schwartz on Environmental Components of Gene-Environ Studies > > NIEHS Director Dr. David Schwartz will be giving a presentation entitled > "> Environmental Components of Gene-Environment Studies> "> on Monday, June 26, 2006 at 4:20 p.m. as part of the Large Population Studies Session of the Secretary's Advisory Committee on Genetics, Health, and Society. You are invited to access the live webcast of this meeting. Information on how to access the webcast will be available on the day of the meeting at > > Agenda > > June 26th will include a review of the Committee's draft report and recommendations on pharmacogenomics and a briefing on Food and Drug Administration's Critical Path Initiative. The Committee also will hear from the Centers for Medicare & Medicaid Services on the status of a proposal to add a genetics specialty to the regulations implementing the Clinical Laboratory Improvement Amendments. In addition, the Committee will discuss the status of its solicitation of public comments on the Committee's draft report "Policy Issues Associated with Undertaking a Large U.S. Population Cohort Project on Genes, Environment, and Disease" (posted at >) and, to further inform the draft report, the Committee will hear presentations on environmental components of gene-environment studies. > > June 27th will begin with several presentations intended to provide the Committee with a better understanding of the impact of gene patents and licensing practices on access to genetic tests and services and the role and economic impact of gene patents in drug and diagnostics development. These presentations will help inform the Committee's next steps on this issue. The Committee will also be updated about the status of Federal genetic non-discrimination legislation and the work of the two interagency work groups regarding the impact of direct-to-consumer marketing of genetic tests. > > An agenda has been posted online at > > > > > > From ntpmail at list.niehs.nih.gov Wed Jun 28 14:07:32 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Jun 28 14:07:59 2006 Subject: NTP UPDATE: Environmental Health Perspectives Message-ID: > June 28, 2006 > > Dear Colleague, > > We are pleased to inform you that the National Institute of Environmental Health Sciences (NIEHS) will continue to publish the scientific journal Environmental Health Perspectives (EHP). > > According to Journal Citation Reports, EHP is now the top ranking journal among 134 Environmental Sciences journals, and top among 93 Public, Environmental and Occupational Health journals. EHP> '> s impact factor increased from 3.92 to 5.34 in just one year from 2004 to 2005. > > As we move forward in publishing EHP, the NIEHS will build upon those principles that have earned the journal a strong reputation and dedicated readership: open access, independent scientific peer-review, and effective oversight for conflict-of-interest. > > In addition, the NIEHS will take some specific steps to further enhance the scientific quality of EHP and to reduce production costs during difficult budgetary times. Those steps include: > > * Identifying a scientist outside NIEHS to serve as Editor-in-Chief, > * Dedicating more of the journal to scientific manuscripts, and reducing the news, commentary and announcement sections, > * Utilizing improved technologies to facilitate the scientific peer-review process and journal production, and > * Continuing partnerships with international scientific journals, while discontinuing translation services. > > Our support of EHP is consistent with the goals set out in the new NIEHS Strategic Plan (available at http://www.niehs.nih.gov/external/plan2006/home.htm). We are committed to communicating high-quality, high-impact science that will assist biomedical and environmental health researchers with their important work. > > Thank you for your ongoing support of EHP. We hope you will continue to use the journal as a key scientific resource. > > Sincerely, > > David A. Schwartz, M.D. > Director, National Institute of Environmental Health Sciences > and National Toxicology Program > > James Burkhart, Ph.D. > Acting Editor-in-Chief, Environmental Health Perspectives > > From ntpmail at list.niehs.nih.gov Tue Jul 11 09:24:38 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Jul 11 09:25:09 2006 Subject: NTP UPDATE: Technical Reports Review Subcommittee to Review Reports August 28, 2006 Message-ID: The NTP Board of Scientific Counselors Technical Reports Review Subcommittee Meeting will be held on August 28, 2006 in the Rall Building at the National Institute of Environmental Health Sciences, 111 T.W. Alexander Drive, Research Triangle Park, NC at 8:30 a.m. and is open to the public. The primary agenda topic is the peer review of the findings and conclusions of five draft NTP Technical Reports of rodent toxicology and carcinogenicity studies conducted by the NTP in genetically modified mouse models. The TRR Subcommittee will also provide advice to the NTP on the utility of GMM models for cancer hazard identification. Draft reports tentatively scheduled for review: GMM-07: Allyl Bromide GMM-09: Dicyclohexylcarbodiimide GMM-08: Benzene GMM-13: Glycidol GMM-12: Phenolphthalein Further information about this meeting is available at http://ntp.niehs.nih.gov/go/15833 From ntpmail at list.niehs.nih.gov Tue Jul 11 15:08:17 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Jul 11 15:08:47 2006 Subject: NTP UPDATE: SACATM Meeting Announcement and request for comment Message-ID: The NTP announces a teleconference meeting of the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) on August 3, 2006. Further information, including Federal Register announcement, background material and online meeting registration are available on the NTP website meeting page: http://ntp.niehs.nih.gov/go/7441 From ntpmail at list.niehs.nih.gov Tue Jul 11 15:19:57 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Jul 11 15:20:23 2006 Subject: NTP UPDATE: NICEATM Panel Report Available Message-ID: The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces the availability of the report "Peer Review Panel Evaluation of the Use of In Vitro Basal Cytotoxicity Test Methods for Estimating Starting Doses for Acute Oral Systemic Toxicity Testing" and requests comments. The Federal Register notice is available on the NTP website (http://ntp.niehs.nih.gov) or go directly to the notice: http://ntp.niehs.nih.gov/index.cfm?objectid=5E83AC12-F1F6-975E-76D5EE8B07F7AA40 From ntpmail at list.niehs.nih.gov Wed Jul 12 13:04:22 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Jul 12 13:04:53 2006 Subject: NTP UPDATE: (no subject) Message-ID: The quarterly issue of the NTP Update is now available on the NTP website at http://ntp.niehs.nih.gov (see July News Update under Latest News). From ntpmail at list.niehs.nih.gov Wed Aug 9 13:28:22 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Aug 9 13:28:37 2006 Subject: NTP UPDATE: Final In Vitro Ocular Background Review Documents Available Message-ID: The final Background Review Documents (BRDs) on the ?Current Status of In Vitro Test Methods for Detecting Ocular Corrosives and Severe Irritants? for the Bovine Corneal Opacity and Permeability, the Isolated Chicken Eye, the Isolated Rabbit Eye, and the Hen?s Egg Test-Chorioallantoic Membrane test methods are now available on-line at http://iccvam.niehs.nih.gov/methods/ocudocs/ocu_brd.htm. For further information, please contact: Dr. William S. Stokes, Director NICEATM, NIEHS 79 T.W. Alexander Drive PO Box 12233 MD EC-17 Research Triangle Park, NC 27709 (Phone) 919-541-2384 (Fax) 919-541-0947 Email: niceatm@niehs.nih.gov, For more information on these test methods, please visit the In Vitro Test Methods for Detecting Ocular Corrosives and Severe Irritants page at http://iccvam.niehs.nih.gov/methods/eyeirrit.htm. The BRDs can be accessed from the ICCVAM home page at http://iccvam.niehs.nih.gov/ through the links in the ?Announcements? box as well. From ntpmail at list.niehs.nih.gov Thu Aug 17 14:06:08 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Aug 17 14:06:23 2006 Subject: NTP UPDATE: NTP announces availability of Proposed Review Process for 12th RoC Message-ID: NTP announces the availability of the Proposed Review Process for the 12th RoC and invites public comments: Federal Register Notice: Vol. 71, No. 159, page 47507 URL: http://ntp.niehs.nih.gov/index.cfm?objectid=1C25C94B-F1F6-975E-75F49F0767FB6 5BB -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060817/a216fe7d/attachment.htm From ntpmail at list.niehs.nih.gov Thu Aug 17 14:11:29 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Aug 17 14:11:39 2006 Subject: NTP UPDATE: NICEATM workshop announcement and data request Message-ID: NICEATM announces a scientific workshop on alternative methods to refine, reduce, or replace the mouse LD[50] assay for botulinum toxin testing and requests in vivo and in vitro data Federal Register Notice: Vol. 71, No. 159 ? pages 47505 ? 47506 URL: http://ntp.niehs.nih.gov/index.cfm?objectid=1CDFF8B7-F1F6-975E-772A909371936 FD2 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060817/4b3cdc6c/attachment.htm From ntpmail at list.niehs.nih.gov Thu Aug 31 08:52:15 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Aug 31 08:52:33 2006 Subject: NTP UPDATE: NOTICE: IOM Workshop Message-ID: The Institute of Medicine?s Roundtable on Environmental Health Sciences, Research, and Medicine, which is sponsored by a consortium of private and public sector agencies including the National Institute of Environmental Health Sciences, will be conducting a two-day workshop on September 14-15th at the National Academies main building. The workshop, >From Exposure to Human Disease: Research Strategies to Address Current Challenges will explore the current challenges facing the field of exposure science along the exposure to disease continuum. NIEHS is sending you this information today to make you aware of this meeting and to encourage your participation in the rich discussion over the two days. The workshop speakers include Dr David Schwartz, Dr Sam Wilson, Dr. Leroy Hood, and Dr David Cox. Recognizing significant progress has been made on a number of exposures over the last 30 years, the workshop will challenge the field to focus on a broader array of exposures, and importantly, to better understand the linkages along the continuum from exposure to disease outcome. Such linkages are needed to improve risk assessment, to increase the validity of epidemiology studies, to enable the identification of genetic and environmental interactions and to increase the utility of exposure information in clinical settings. In addition to toxicity of a substance, factors such as the type of exposure, length of exposure, genetic polymorphisms, and age of an individual, determine whether an exposure will lead to a disease outcome. In an effort to increase our knowledge and understanding of the interface between environmental agents and human disease, this workshop will discuss the current state of knowledge along the exposure?disease continuum, the current exposure challenges for the future, and the research and policy strategies to inform the science. The workshop will draw from the scientific advances in genomics, proteomics, and biomarkers in order to discuss opportunities to provide insight into the exposure?disease linkages and build on increased knowledge in nutrition and stress research, and improved computer modeling to examine ways to make better linkages across the continuum. The workshop is free and open to the public, but does require advance registration. To see a complete agenda and to register, please visit the workshop?s web site at http://www.iom.edu/?id=36630. If you have any further questions regarding the workshop, please call the project staff at (202) 334-2548. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060831/a1b04e7f/attachment.htm From ntpmail at list.niehs.nih.gov Thu Aug 31 15:19:04 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Aug 31 15:19:19 2006 Subject: NTP UPDATE: Vacancy Announcement for Associate Director, National Toxicology Program, Division of Intramural Research, NIEHS Message-ID: Applications are currently being accepted for the tenured position of Associate Director, National Toxicology Program, Division of Intramural Research, NIEHS. To access the complete vacancy announcement, click on website http://www.niehs.nih.gov/vacancy/tenutrac/dir06-05.htm -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060831/3fe07979/attachment.htm From ntpmail at list.niehs.nih.gov Thu Sep 28 11:13:05 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Sep 28 11:13:15 2006 Subject: NTP UPDATE: NICEATM announces availability of revised list Message-ID: In today?s Federal Register, NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM); Notice of Availability of a Revised List of Recommended Reference Substancesfor Validation of In Vitro Estrogen and Androgen Receptor Binding and Transcriptional Activation Assays See FR Notice at URL: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=F4C433CE-F1F6-975E-7E6585 CC101328D8 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060928/339f8ba1/attachment.htm From ntpmail at list.niehs.nih.gov Fri Sep 29 15:00:34 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Sep 29 15:02:17 2006 Subject: NTP UPDATE: Message from David Schwartz, NIEHS Children's Environmental Health Research Message-ID: Dear Colleague, Children?s health is a top priority at NIEHS and we are committed to making the most of every research dollar. To achieve this goal, the Institute is conducting a review of the many ways it can fund research on children?s environmental health. The purpose of the review is to identify the best possible ways of supporting research on the links between environmental exposures and childhood disease. In conducting this review, the NIEHS will evaluate a number of scientific strategies to determine the most effective method for achieving three primary goals as they relate to children?s environmental health research: 1) to stimulate future research on the role of environment in the etiology of disease/dysfunction among children, 2) to develop novel effective intervention and prevention strategies, and 3) to promote translation of basic research findings into applied intervention and prevention methods, thereby enhancing awareness among children, their families, and health care practitioners regarding detection, treatment, and prevention of environmentally related diseases and health conditions. An independent review panel, convened by the Institute?s Office of Risk Assessment Research, will review the Children?s Centers Program and its portfolio of investigator-initiated research on children?s health. This review panel will consist of 12 senior scientists with diverse expertise in children?s environmental health research. The panel will be convened as a working group to the NIEHS National Advisory Environmental Health Sciences Council. The review process will include two opportunities for public input. On January 22-24, 2007, the NIEHS will hold a public workshop to explore strategies for addressing emerging issues in children?s environmental health research. In February, the panel report will be delivered to NIEHS and made available for public comment. An official notice of the report will appear in the Federal Register. Over the past 30 years, the NIEHS has invested millions of dollars in children?s environmental health research. For the past eight years, the Institute has partnered with the U.S. Environmental Protection Agency to support thirteen research centers devoted exclusively to children?s environmental health and disease prevention. These centers draw upon the resources of community partners and the expertise of top universities and medical centers to focus on the important role that environmental toxicants play in the development of asthma, autism, and other childhood illnesses. The information obtained from this independent review will enable the NIEHS to continue its support of basic and applied research that shows the greatest promise for rapidly identifying links between environmental exposures and childhood illnesses. This is a vital component of the Institute?s overall commitment to the detection, prevention and treatment of environmentally-related diseases in America?s children. Sincerely, David A. Schwartz, M.D. Director, National Institute of Environmental Health Sciences and National Toxicology Program -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20060929/e6f68aa3/attachment.htm From ntpmail at list.niehs.nih.gov Mon Oct 2 09:37:08 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Oct 2 09:37:36 2006 Subject: NTP UPDATE: ICCVAM Scientific Workshop Message-ID: A Scientific Workshop on Alternative Methods to Refine, Reduce, and Replace the Mouse LD50 Assay For Botulinum Toxin Testing will be held on Nov. 13-14, 2006 from 8:30 am - 5:00 pm at the Crowne Plaza Hotel in Silver Spring, MD. The workshop is being organized by the Interagency Coordinating Committee on the Validation of Alternative Methods (OCCAM), the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), and the European Center for the Validation of Alternative Methods (ECVAM) The purpose of the workshop is to review the state-of-the-science and current knowledge regarding alternative methods for reducing, replacing, and refining (less pain and distress) the use of mice for botulinum toxin testing, and to identify priority research, development, and validation efforts needed to further reduce, refine and/or replace animal use for botulinum toxin testing. Posters are being solicited for this workshop. See the workshop website at http://iccvam.niehs.nih.gov/methods/biolodocs/biolowkshp/wkshpinfo.htm for further information on the poster session and for registering for the workshop. The deadline for poster abstract submissions is September 29, 2006. Additional information can be obtained from NICEATM at the address below. The workshop was previously announced in an email to this list on August 17, 2006 and formally in the Federal Register (Volume 71, Number 159 Pages 47505-47506) on that same date. Copies of the FR notice can be found at: http://iccvam.niehs.nih.gov/docs/FR/7147505.pdf in PDF or http://iccvam.niehs.nih.gov/docs/FR/7147505.htm in HTML. This notice can also be accessed through the ICCVAM home page at http://iccvam.niehs.nih.gov -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061002/1e309ecf/attachment.htm From ntpmail at list.niehs.nih.gov Thu Oct 5 10:30:19 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Oct 5 10:36:08 2006 Subject: NTP UPDATE: Exposure Biology RFAs =?iso-8859-1?q?=AD_?= Spread the News Message-ID: The NIEHS wants to bring to your attention five new funding opportunities provided by the NIH, under the Genes and Environment Initiative (GEI) ? Exposure Biology Program: RFA-ES-06-011 ? Environmental Sensors for Personal Exposure Assessment (U01) http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-06-011.html RFA-ES-06-012 ? Biological Response Indicators of Environmental Stress Centers (U54) http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-06-012.html RFA-ES-06-013 ? Biological Response Indicators of Environmental Stress (U01) http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-06-013.html RFA-CA-07-032 ? Improved Measures of Diet and Physical Activity for the Genes and Environment Initiative (GEI) (U01) http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-07-032.html RFA-DA-07-005 ? Field-Deployable Tools for Quantifying Exposures to Psychosocial Stress and to Addictive Substances for Studies of Health and Disease (U01) http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-07-005.html The Genes and Environment Initiative (GEI) is a four-year, NIH-wide program, which aims to accelerate understanding of genetic and environmental contributions to health and disease. The Exposure Biology Program will focus on the development of innovative technologies to measure environmental exposures, diet, physical activity, psychosocial stress, and addictive substances that contribute to the development of disease. The program will support: (1) development of environmental sensors for measurement of chemicals, dietary intake, physical activity, and psychosocial stressors and addictive substances; (2) development of markers of biological response via common pathogenic mechanisms such as oxidative stress, epigenetic modifications, and DNA damage; (3) integration of biological responses with the development of biosensors; and (4) application of novel assays and biomarkers to studies of gene-environment interaction. Contact information for each of funding opportunity announcements is available within each of the RFAs, as well as on the GEI-Exposure Biology Program website: http://www.gei.nih.gov/exposurebiology/index.asp. For those who are interested, an Application Information Meeting will be held at the National Institute of Environmental Health Sciences (NIEHS) on Friday, October 20, 2006. Details of the meeting, as well as an online registration form, are available at http://www.gei.nih.gov/exposurebiology/meetings/appinfo06/. We hope you will take advantage of this very exciting opportunity that could lead to new and innovative approaches to the study of gene-environmental interaction. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061005/555f2ae9/attachment.htm From ntpmail at list.niehs.nih.gov Thu Oct 5 15:12:26 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Oct 5 15:15:47 2006 Subject: NTP UPDATE: New PR: New Clinical Research Facility Focusing on Environmental Health to Open at NIEHS in Research Triangle Park, NC Message-ID: The first outpatient clinical research facility is being established at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, to help bridge the gap between research and patient care and to train future generations of physician-scientists. Initially, clinical studies in the new facility will have a strong focus on pulmonary exposures and diseases such as asthma. The NIEHS expects to begin accepting patients by summer 2007. "Having a place on the NIEHS campus for physician-scientists to see patients will allow us to focus our research on scientific questions that are clinically relevant," says NIEHS Director, David A. Schwartz, M.D. "Not only is it a great opportunity for our in-house scientists, but it also allows us to give something back to the community." To read the entire press release, please see http://www.niehs.nih.gov/oc/news/clinical.htm -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061005/4845930e/attachment.htm From ntpmail at list.niehs.nih.gov Tue Oct 10 09:50:08 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Oct 10 09:50:40 2006 Subject: NTP UPDATE: Upcoming NRC Workshop: Use of Toxicogenomics to Understand Toxic Effects and Improve Risk Assessment Message-ID: Skipped content of type multipart/alternative-------------- next part -------------- A non-text attachment was scrubbed... Name: not available Type: image/jpeg Size: 12355 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061010/6e7bb377/attachment.jpg -------------- next part -------------- A non-text attachment was scrubbed... Name: not available Type: image/jpeg Size: 22403 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061010/6e7bb377/attachment-0001.jpg From ntpmail at list.niehs.nih.gov Wed Oct 11 11:24:06 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Oct 11 11:24:16 2006 Subject: NTP UPDATE: Upcoming NRC Workshop on Use of Toxicogenomics to Understand Toxic Effects and Improve Risk Assessment Message-ID: Note: Due to system error preventing this listserv from being delivered to all intended recipients, it is being resent. Please disregard it if you received the original listserv message on 10/10/2006. Below is an announcement for an upcoming workshop held by the National Research Council Committee (NRC) on Emerging Issues and Data on Environmental Contaminants. ?We encourage you to attend this meeting to learn about recent scientific advances in toxicogenomics and their implications for risk assessment. Workshop Title: ?Use of Toxicogenomics to Understand Toxic Effects and Improve Risk Assessment Purpose: This workshop will seek to identify how current toxicogenomic information can be used to inform risk assessment today and to identify toxicogenomic research directions to facilitate risk assessment in the future. ?Two chemicals of regulatory and scientific interest, dibutyl phthalate and benzene, will be used as case studies to highlight the current use, controversies, and potential for using toxicogenomic information in risk assessment. ??? Format: ?Presentations highlighting recent toxicogenomic research and chemical risk assessments will be followed by focused discussions among NRC committee members, invited speakers, and audience participants. ?During focused discussions, workshop moderators will seek to address questions with input derived from workshop presentations and from participant discussions. ?The result of these discussions will be presented at the end of the workshop. Types of questions to be addressed: What are the salient controversies in the health effects or risk assessment of these chemicals? ?What do we currently know about mechanisms of toxic effects? ?What type of information is appearing about this chemical in the toxicogenomics literature? ?What does this information tell us to date? ?Can chemical specific risk assessments be improved by these data? ?What are the most important directions for further research in order to develop information that will be useful to regulators? ?What omics technologies might be useful in further developing this information? ?Why is this information important in terms of medical treatment or public health and how can this information be used in the future to protect public health? ? Date: ??????????????November 13th, 2006 Agenda: ??????????8:30 AM to 5:00 PM; a full agenda will be provided shortly Location: ???????Keck Center for the National Academies ????????????????????????500 Fifth St. NW ????????????????????????Washington DC 20001 Please RSVP to emergingissues@nas.edu ?if you plan to attend this workshop. ? The NRC Committee on Emerging Issues and Data on Environmental Contaminants is sponsored by the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH). ?The NRC committee serves as a pubic forum among government, industry, environmental groups, and the academic community about emerging issues in toxicogenomics, environmental toxicology, risk assessment, exposure assessment, and other related fields. ?For more information, see the committee?s website at: http://dels.nas.edu/emergingissues/. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061011/b5f5c722/attachment.htm From ntpmail at list.niehs.nih.gov Mon Oct 16 15:00:26 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Oct 16 15:01:14 2006 Subject: NTP UPDATE: NTP October Update Message-ID: Skipped content of type multipart/alternative-------------- next part -------------- A non-text attachment was scrubbed... Name: NTPU_Oct2006.pdf Type: application/pdf Size: 376174 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061016/fa33eedf/NTPU_Oct2006.pdf From ntpmail at list.niehs.nih.gov Mon Oct 16 15:57:26 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Oct 16 15:57:30 2006 Subject: NTP UPDATE: CERHR announced availability of Draft Hydroxyurea report Message-ID: NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the availability of the draft expert panel report on hydroxyurea, requests public comment on the draft report and announces the hydroxyurea expert panel meeting. Federal Register Notice issued October 16, 2006 (71 FR 199 pages 60746 ? 60748) at URL: http://ntp.niehs.nih.gov/index.cfm?objectid=51949BBD-F1F6-975E-7916743D11EB4 1E5 Or by linking to the Federal Register Notices page on the NTP website at URL: http://ntp.niehs.nih.gov/go/frn -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061016/0ea27f43/attachment.htm From ntpmail at list.niehs.nih.gov Mon Oct 16 16:02:07 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Oct 16 16:02:12 2006 Subject: NTP UPDATE: NICEATM notice of Availability of Pre-Screen Evaluation Assay Message-ID: NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces the availability of the NICEATM Pre-Screen Evaluation of a Cell Proliferation Assay to Detect Estrogenic Activity; Request for Comments and Nominations of other In Vitro Endocrine Disruptor Test Methods. Federal Register Notice issued October 16, 2006 (71 FR 199 pages 60748 ? 60749) at URL: http://ntp.niehs.nih.gov/index.cfm?objectid=5195EB07-F1F6-975E-7353F3A40B98E AAA Or by linking to the Federal Register Notices page on the NTP website at URL: http://ntp.niehs.nih.gov/go/frn -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061016/aa7bdae3/attachment.htm From ntpmail at list.niehs.nih.gov Wed Oct 25 09:01:45 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Oct 25 09:02:19 2006 Subject: NTP UPDATE: SACATM meeting announced & CERHR Hydroxyurea Expert Panel Roster corrected Message-ID: * The NTP announces the November 30, 2006 meeting of the Scientific Advisory Committee for Alternative Toxicological Methods (SACATM) and requests comments. See Federal Register: http://ntp.niehs.nih.gov/index.cfm?objectid=7F499951-F1F6-975E-711ADBE5A6D65 1C0 * The NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) corrects Hydroxyurea Expert Panel Roster ? See Federal Register: http://ntp.niehs.nih.gov/index.cfm?objectid=7F48A28F-F1F6-975E-719974BBA3C80 DB8 The October 16, 2006 Federal Register Notice announced the availability of the draft expert panel report on hydroxyurea and request for public comment on the draft report and meeting announcement (see notice: http://ntp.niehs.nih.gov/index.cfm?objectid=51949BBD-F1F6-975E-7916743D11EB4 1E5 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061025/eb332bb2/attachment.htm From ntpmail at list.niehs.nih.gov Wed Oct 25 09:31:47 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Oct 25 09:32:18 2006 Subject: NTP UPDATE: SACATM meeting announced & CERHR Hydroxyurea expert panel roster corrected Message-ID: Note: This message is being resent due to a link error in the first message. * The NTP announces the November 30, 2006 meeting of the Scientific Advisory Committee for Alternative Toxicological Methods (SACATM) and requests comments. See Federal Register: http://ntp.niehs.nih.gov/index.cfm?objectid=7F499951-F1F6-975E-711ADBE5A6D65 1C0 * The NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) corrects the hydroxyurea expert panel roster. See Federal Register: http://ntp.niehs.nih.gov/index.cfm?objectid=7F48A28F-F1F6-975E-719974BBA3C80 DB8 > On October 16, 2006 CERHR announced the availability of the draft expert panel > report on hydroxyurea; request for public comment on the draft report; and > meeting announcement. Refer to Federal Register: http://ntp.niehs.nih.gov/index.cfm?objectid=51949BBD-F1F6-975E-7916743D11EB4 1E5 All Federal Register Notices are located on the NTP website at URL: http://ntp.niehs.nih.gov/ -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061025/56f000b3/attachment.htm From ntpmail at list.niehs.nih.gov Wed Nov 1 09:08:04 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Nov 1 09:08:34 2006 Subject: NTP UPDATE: NTP Announces December 1 Board of Scientific Counselors Meeting Message-ID: The NTP Board of Scientific Counselors will meet on December 1, 2006. For additional information, see the meeting page: http://ntp.niehs.nih.gov/go/165 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061101/152d3f9f/attachment.htm From ntpmail at list.niehs.nih.gov Tue Nov 7 08:22:35 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Nov 7 08:22:37 2006 Subject: NTP UPDATE: Vacancy Announcement for Toxicologist, GS-415-13/14 Message-ID: Currently applications are being accepted for the position of Toxicologist, GS-0415-13/14, in the DIT/ETP/TOB. This vacancy is a full-time permanent position being announced under both delegated examining (DEU) and merit promotion procedures. The position is not in the bargaining unit. The position closes on December 8, 2006. To view the full vacancy announcement, click on the link below: http://jobsearch.usajobs.opm.gov/getjob.asp?JobID=49691582&AVSDM=2006%2D11%2 D06+00%3A01%3A04&Logo=0&q=niehs-07-153939&FedEmp=Y&sort=rv&vw=d&brd=3876&ss= 0&FedPub=Y&SUBMIT1.x=71&SUBMIT1.y=20 (DEU announcement) http://jobsearch.usajobs.opm.gov/getjob.asp?JobID=49692369&AVSDM=2006%2D11%2 D06+00%3A01%3A04&Logo=0&q=niehs-07-153939&FedEmp=Y&sort=rv&vw=d&brd=3876&ss= 0&FedPub=Y&SUBMIT1.x=71&SUBMIT1.y=20 (Merit promotion announcement) -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061107/af1da65e/attachment.htm From ntpmail at list.niehs.nih.gov Wed Nov 8 14:11:13 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Nov 8 14:11:43 2006 Subject: NTP UPDATE: CERHR announces Draft Briefs on Genistein & Soy Formula Message-ID: The National Toxicology Program (NTP); Center for the Evaluation of Risks to Human Reproduction (CERHR); Availability of the Draft NTP Briefs on Genistein and Soy Formula; Request for Public Comments. See Federal Register Notice: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=C8E49B7C-F1F6-975E-718655 3B34FD9415 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061108/5ff9fb81/attachment.htm From ntpmail at list.niehs.nih.gov Mon Nov 13 13:23:52 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Nov 13 13:24:33 2006 Subject: NTP UPDATE: NICEATM/ICCVAM Announces 5-Year Plan; invites public comments Message-ID: The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods; Development of a NICEATM/ICCVAM 5-Year Plan To Research, Develop, Translate, and Validate New and Revised Non-animal and Other Alternative Assays for Integration of Relevant and Reliable Methods Into Federal Agency Testing Programs: Request for Public Comments. For additional information see: http://iccvam.niehs.nih.gov/docs/5yearplan.htm -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061113/3b148e99/attachment.htm From ntpmail at list.niehs.nih.gov Tue Nov 14 09:14:11 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Nov 14 09:14:45 2006 Subject: NTP UPDATE: Nanotechnology RFA Message-ID: Nanotechnology Update NIOSH, NIH, and EPA Jointly Announce Funding Opportunity NIOSH joined with the National Institutes of Health and the U.S. Environmental Protection Agency to solicit grant applications for research that will explore interactions between engineered nanomaterials and bodily systems. Grant applications are now being accepted under the announcement: Manufactured Nanomaterials: Physico-chemical Principles of Biocompatibility and Toxicity (R01). The deadline for letters of intent is December 13, 2006. For more information, visit http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-06-008.html. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061114/088786f2/attachment.htm From ntpmail at list.niehs.nih.gov Tue Nov 14 13:28:56 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Nov 14 13:29:35 2006 Subject: NTP UPDATE: Upcoming NIEHS Workshop: Children's Environmental Health Research: Past, Present and Future In-Reply-To: <8BB67CD070A6EE479378FBE1CEB794780110AB17@NIHCESMLBX6.nih.gov> Message-ID: Whendo you want it to go? On 11/14/06 1:27 PM, "Thayer, Kristina (NIH/NIEHS) [E]" wrote: > Can we send this out on the NTP listserve? > > ---------- > > Below is an announcement for an upcoming workshop sponsored by the National > Institute of Environmental Health Sciences (NIEHS) on research approaches for > addressing children?s environmental health. > > Title: Children?s Environmental Health Research: Past, Present and Future > > Purpose: The goal of this workshop is to develop new strategies for research, > exposure and effects monitoring, intervention and prevention in children's > environmental health. Specific objectives are to maximize the effectiveness of > scientific research - basic science, exposure monitoring/biomonitoring, > epidemiology, toxicology, clinical medicine and multidisciplinary studies - > and to enhance the translation of research to the bedside, to the community > and to public policy. > > Format: The first day will begin with discussions of two case studies that > demonstrate the successful implementation of evidence-based > intervention/prevention strategies that became possible once links between > environmental exposures and a disease in children had been identified. The > first case study will focus on lead and neurotoxicity. Findings on the adverse > effects of lead on neurodevelopment ultimately led to efforts to reduce > exposures to lead. Asthma will be used as a second case study because it > provides a clear example of environmental triggers and some science-based > prevention/intervention strategies that are already being implemented. The > second day of the workshop will focus on applying lessons learned from the two > "success" case studies to two children's disorders that appear to have > environmental etiologies but are less well understood: disorders of lipid and > carbohydrate metabolism and attention deficit/hyperactivity disorder (ADHD). > > A discussion will follow each case study presentation to consider the > opportunities, the barriers and the design challenges that confront future > clinical, toxicological, epidemiological, exposure monitoring, and basic > research in children's environmental health. Specific topics include: > * Past approaches to research translation to see what worked and what failed > to work. > * The critical mass of researchers and mix of disciplines needed to most > efficiently advance research in children's environmental health. > * Biomarkers of exposure, susceptibility, or subclinical dysfunction. > * The use of "omics" technologies that might be incorporated into future > toxicological, epidemiological and/or biomonitoring studies to enhance their > sensitivity and efficiency. > * Is there a point at which the use of new scientific tools might slow the > pace of progress? > * New approaches to accelerating the translation of science to treatment, > prevention, and the remediation of environmental risks to children's health. > * Potential study populations at uniquely high risk of disease. > * Data resources - records, disease registries, well-characterized cohort > populations, tissue banks, or stored DNA - in the U.S. or abroad that might > facilitate future studies. > * New partnerships in research. > This meeting is open to the public with time set aside for public discussion. > > Date: January 22-23, 2007 > > Location: Rodbell Auditorium, Rall Building > > National Institute of Environmental Health Sciences > 111 T.W. Alexander Drive > Research Triangle Park, NC 27709 > > > > Meeting Website: > http://www-apps.niehs.nih.gov/conferences/od/cehr/location.cfm > > For additional information, contact Dr. Kristina Thayer (thayer@niehs.nih.gov > or 919-541-5021). > > > -- Mary S. Wolfe, Ph.D. Director, NTP Liaison and Scientific Review Office NIH/NIEHS P.O. Box 12233, MD A3-01 111 TW Alexander Dr Research Triangle Park, NC 27709 (919) 541-0530 wolfe@niehs.nih.gov -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061114/9dfce561/attachment.htm From ntpmail at list.niehs.nih.gov Tue Nov 14 14:34:46 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Nov 14 14:35:33 2006 Subject: NTP UPDATE: Upcoming NIEHS workshop Message-ID: Below is an announcement for an upcoming workshop sponsored by the National Institute of Environmental Health Sciences (NIEHS) on research approaches for addressing children?s environmental health. Title: Children?s Environmental Health Research: Past, Present and Future Purpose: The goal of this workshop is to develop new strategies for research, exposure and effects monitoring, intervention and prevention in children's environmental health. Specific objectives are to maximize the effectiveness of scientific research - basic science, exposure monitoring/biomonitoring, epidemiology, toxicology, clinical medicine and multidisciplinary studies - and to enhance the translation of research to the bedside, to the community and to public policy. Format: The first day will begin with discussions of two case studies that demonstrate the successful implementation of evidence-based intervention/prevention strategies that became possible once links between environmental exposures and a disease in children had been identified. The first case study will focus on lead and neurotoxicity. Findings on the adverse effects of lead on neurodevelopment ultimately led to efforts to reduce exposures to lead. Asthma will be used as a second case study because it provides a clear example of environmental triggers and some science-based prevention/intervention strategies that are already being implemented. The second day of the workshop will focus on applying lessons learned from the two "success" case studies to two children's disorders that appear to have environmental etiologies but are less well understood: disorders of lipid and carbohydrate metabolism and attention deficit/hyperactivity disorder (ADHD). A discussion will follow each case study presentation to consider the opportunities, the barriers and the design challenges that confront future clinical, toxicological, epidemiological, exposure monitoring, and basic research in children's environmental health. Specific topics include: * Past approaches to research translation to see what worked and what failed to work. * The critical mass of researchers and mix of disciplines needed to most efficiently advance research in children's environmental health. * Biomarkers of exposure, susceptibility, or subclinical dysfunction. * The use of "omics" technologies that might be incorporated into future toxicological, epidemiological and/or biomonitoring studies to enhance their sensitivity and efficiency. * Is there a point at which the use of new scientific tools might slow the pace of progress? * New approaches to accelerating the translation of science to treatment, prevention, and the remediation of environmental risks to children's health. * Potential study populations at uniquely high risk of disease. * Data resources - records, disease registries, well-characterized cohort populations, tissue banks, or stored DNA - in the U.S. or abroad that might facilitate future studies. * New partnerships in research. This meeting is open to the public with time set aside for public discussion. Date: January 22-23, 2007 Location: Rodbell Auditorium, Rall Building National Institute of Environmental Health Sciences 111 T.W. Alexander Drive Research Triangle Park, NC 27709 Meeting Website: http://www-apps.niehs.nih.gov/conferences/od/cehr/location.cfm For additional information, contact Dr. Kristina Thayer (thayer@niehs.nih.gov or 919-541-5021). -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061114/7d384c0e/attachment.htm From ntpmail at list.niehs.nih.gov Fri Nov 17 14:38:59 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Nov 17 14:39:15 2006 Subject: NTP UPDATE: ICCVAM Biennial Progress Report now available Message-ID: NICEATM announces the availability of the Biennial Progress Report of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). Learn more: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=F62794A7-F1F6-975E-752C4C 67A3D75A51 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061117/57bba06f/attachment.htm From ntpmail at list.niehs.nih.gov Thu Dec 14 08:49:33 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Dec 14 08:49:42 2006 Subject: NTP UPDATE: NICEATM announces peer review meeting on pyrogenicity testing methods Message-ID: The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces the independent scientific peer review meeting on the use of in vitro pyrogenicity testing methods and requests public comments. URL: http://ntp.niehs.nih.gov/index.cfm?objectid=77556660-F1F6-975E-7BB75F363FD76 6A5 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061214/b92909e6/attachment.htm From ntpmail at list.niehs.nih.gov Thu Dec 14 08:51:01 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Dec 14 08:51:25 2006 Subject: NTP UPDATE: CERHR Bisphenol A Draft Report available Message-ID: NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the availability of the draft expert panel report on Bisphenol A, requests public comments and announces Bisphenol A expert panel meeting. URL: http://ntp.niehs.nih.gov/index.cfm?objectid=7751D799-F1F6-975E-7360A6FA26A47 ABC -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061214/046c2acd/attachment.htm From ntpmail at list.niehs.nih.gov Fri Dec 15 10:46:59 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Dec 15 10:47:30 2006 Subject: NTP UPDATE: Updated Status Information Message-ID: NTP results and status information for all NTP studies has been updated; you may search testing status of agents using the following url: > http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: > http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061215/e7f7de72/attachment.htm From ntpmail at list.niehs.nih.gov Fri Dec 15 14:06:59 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Dec 15 14:07:36 2006 Subject: NTP UPDATE: DEHP Monograph Message-ID: CERHR announces the newly released document, NTP-CERHR Monograph on the Potential Human Reproductive and Development Effects of DEHP http://cerhr.niehs.nih.gov/chemicals/dehp/dehp-eval.html -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061215/d2bc360d/attachment.htm From ntpmail at list.niehs.nih.gov Mon Dec 18 16:01:13 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Dec 18 16:01:53 2006 Subject: NTP UPDATE: Final NTP TR-531 now available Message-ID: The final TR-531, NTP Toxicology and Carcinogenesis Studies of a Binary Mixture of PCB 126 and PCB 118 in Female Harlan Sprague-Dawley Rats (Gavage Studies) is now available. See URL: http://ntp.niehs.nih.gov/go/tr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061218/08a48941/attachment.htm From ntpmail at list.niehs.nih.gov Wed Dec 20 10:26:06 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Dec 20 10:26:11 2006 Subject: NTP UPDATE: NTP TR-534 now available Message-ID: The final TR-534, NTP Toxicology and Carcinogenesis Studies of Divinylbenzene-HP (CAS No. 1321-74-0) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) is now available. See URL: http://ntp.niehs.nih.gov/go/tr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061220/d19901c7/attachment.htm From ntpmail at list.niehs.nih.gov Thu Dec 21 15:14:08 2006 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Dec 21 15:14:40 2006 Subject: NTP UPDATE: NTP TR-526 now available Message-ID: The final TR-526, NTP Toxicology and Carcinogenesis Studies of a Mixture of TCDD, PeCDF, and PCB 126 (CAS Nos. 1746-01-6, 57117-31-4, 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage Studies) is now available. See URL: http://ntp.niehs.nih.gov/go/tr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20061221/234b6409/attachment.htm