From ntpmail at list.niehs.nih.gov Fri Jan 12 09:49:24 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Jan 12 09:49:33 2007 Subject: NTP UPDATE: NTP News Update - January 2007 Message-ID: The NTP News Update for January 2007 is now available at URL: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=16BD253C-F1F6-975E-767833 FEAE4D176A -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070112/310bc7ec/attachment.htm From ntpmail at list.niehs.nih.gov Wed Jan 17 12:41:22 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Jan 17 12:41:31 2007 Subject: NTP UPDATE: NTP TR-535 now available Message-ID: The final TR-535, NTP Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies) is now available. See URL: http://ntp.niehs.nih.gov/go/tr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070117/b222eda7/attachment.htm From ntpmail at list.niehs.nih.gov Mon Jan 22 08:54:47 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jan 22 08:55:25 2007 Subject: NTP UPDATE: 2007 Conference of the International Society of Exposure Analysis Message-ID: Skipped content of type multipart/alternative-------------- next part -------------- A non-text attachment was scrubbed... Name: call for abstracts final 132007.doc Type: application/octet-stream Size: 586752 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070122/66b40eae/callforabstractsfinal132007.obj From ntpmail at list.niehs.nih.gov Mon Jan 22 09:26:48 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jan 22 09:26:58 2007 Subject: NTP UPDATE: Updated Status Information Message-ID: NTP results & status information for all NTP studies has been updated; you may search testing status of agents using the following url: http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070122/0b385fd2/attachment.htm From ntpmail at list.niehs.nih.gov Wed Feb 21 09:35:52 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Feb 21 09:36:00 2007 Subject: NTP UPDATE: Updated NTP Testing Status Message-ID: NTP results & status information for all NTP studies has been updated; you may search testing status of agents using the following url: http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070221/ed0b958e/attachment.htm From ntpmail at list.niehs.nih.gov Fri Feb 23 16:00:22 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Feb 23 16:00:36 2007 Subject: NTP UPDATE: NTP TOX-72 now available Message-ID: The final TOX-72, NTP Toxicity Report on Toxicity Studies of Sodium Dichromate Dihydrate (CAS 7789-12-0) Administered in Drinking Water to Male and Female F344/N Rats and B6C3F1 Mice and Male BALB/c and am3-C57BL/6 Mice is now available. See URL: http://ntp.niehs.nih.gov/go/14372 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070223/a0666de5/attachment.htm From ntpmail at list.niehs.nih.gov Mon Feb 26 14:59:17 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Feb 26 14:59:49 2007 Subject: NTP UPDATE: CERHR announces availability of Hydroxyurea report and reminder of independent panel evaluation of Bisphenol A Message-ID: * NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the availability of the Hydroxyurea expert panel report and request public comment. See FR Notice: http://ntp.niehs.nih.gov/index.cfm?objectid=FF7E8CEF-F1F6-975E-7CD3A67D030E8 823 > * CERHR also announces the Independent Panel to evaluate Bisphenol A to be held March 5-7, 2007. See News Advisory: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=FF887B0F-F1F6-975E-7A29D1 C9CDA56F50 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070226/fcb4d62e/attachment.htm From ntpmail at list.niehs.nih.gov Fri Mar 2 12:03:31 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Mar 2 12:03:22 2007 Subject: NTP UPDATE: NTP{ announces Message-ID: The National Toxicology Program announces the May 16-17, 2007 meeting of the Board of Scientific Counselors Technical Reports Review Subcommittee and requests comments. The meeting page can be found at URL: http://ntp.niehs.nih.gov/go/15833 Federal Register Notice: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=13815C89-F1F6-975E-753BEE 786032690F -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070302/357de582/attachment.htm From ntpmail at list.niehs.nih.gov Thu Mar 8 10:55:22 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Mar 8 10:55:52 2007 Subject: NTP UPDATE: Availability of Pathology Data Tables for NTP Studies Message-ID: Pathology data tables for reports P03, P09, P10, P18 for the Sodium Dichromate Dihydrate study have been revised and may be viewed at URL: http://ntp.niehs.nih.gov/go/29141 The NTP Pathology Working Group has reviewed the following studies and final pathology tables have been generated. The complete set of data tables for these studies (body weight, clinical observations, survival, and pathology) are available on the NTP website at URL: http://ntp.niehs.nih.gov/go/peerreview > TR-541 Formamide > TR-542 Cumene > TR-544 Dibromoacetonitrile > TR-546 Sodium Dichromate Dihydrate > TR-549 Bromochloroacetic Acid > TR-550 Cresols > TR-551 Isoeugenol > TR-552 Propargyl Alcohol > TR-554 5-(Hydroxymethyl)-2-furfural > TR-555 1,2-Dibromo-2,4-dicyanobutane > TR-(tbd) Chromium Picolinate Monohydrate > TOX-60 Peroxisome Project (Dibutylphthalate) > TOX-62 Peroxisome Project (WY-14,643) > TOX-63 Peroxisome Project (2,4-Dichlorophenoxyacetic acid) > TOX-64 Peroxisome Project (Gemfibrozil) > TOX-75 Dimethylaminopropyl Chloride Hydrochloride > TOX-76 2,4-Hexadienal > TOX-77 Hexachlorobenzene > TOX-81 alpha-Pinene -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070308/30bf1405/attachment.htm From ntpmail at list.niehs.nih.gov Fri Mar 16 10:35:47 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Mar 16 10:35:58 2007 Subject: NTP UPDATE: Updated NTP Testing Status Message-ID: NTP results & status information for all NTP studies has been updated; you may search testing status of agents using the following url: http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070316/fe94d1a9/attachment.htm From ntpmail at list.niehs.nih.gov Wed Mar 21 11:59:20 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Mar 21 11:59:55 2007 Subject: NTP UPDATE: NTP at the Society of Toxicology 46th Annual Meeting and ToxExpo Message-ID: Skipped content of type multipart/alternative-------------- next part -------------- A non-text attachment was scrubbed... Name: ScheduleSOT2007V2.pdf Type: application/pdf Size: 404793 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070321/656ce419/ScheduleSOT2007V2.pdf From ntpmail at list.niehs.nih.gov Sun Apr 1 17:53:43 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Sun Apr 1 17:54:16 2007 Subject: NTP UPDATE: Toxicological Study Nominations Announced; Comments Requested Message-ID: The NTP office of Chemical Nomination and Selection announcement of and request for public comment on Toxicological Study Nominations to the NTP. Federal Register Announcement: http://ntp.niehs.nih.gov/index.cfm?objectid=AF0BAC2C-F1F6-975E-75C014AE91EBC 6C2 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070401/da60d9d4/attachment.htm From ntpmail at list.niehs.nih.gov Mon Apr 2 13:11:13 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Apr 2 13:11:27 2007 Subject: NTP UPDATE: NTP News Update - April 2007 Message-ID: The NTP News Update for April 2007 is now available at URL: http://ntp.niehs.nih.gov/go/29068 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070402/7696030a/attachment.htm From ntpmail at list.niehs.nih.gov Mon Apr 2 14:33:33 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Apr 2 14:34:30 2007 Subject: NTP UPDATE: CERHR announces 2nd Bisphenol A meeting & interim report Message-ID: The Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the Second Bisphenol A Expert Panel Meeting, availability of Interim Draft Report, and requests public comment. You may view the Federal Register Notice at the URL: http://ntp.niehs.nih.gov/index.cfm?objectid=B3787081-F1F6-975E-7A4B46066CDCE 421 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070402/71136d22/attachment.htm From ntpmail at list.niehs.nih.gov Wed Apr 4 16:33:53 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Apr 4 16:34:02 2007 Subject: NTP UPDATE: Technical Reports TR-523 & TR-538 now available Message-ID: Final National Toxicology Program technical reports are now available for the following studies: TR-523: Toxicology and Carcinogenesis Studies of Diisopropylcarbodiimide (CAS No. 693-13-0) in F344/N Rats and B6C3F1 Mice (Dermal Studies) TR-538: Toxicology and Carcinogenesis Studies of Methyl Isobutyl Ketone (CAS No. 108-10-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) See URL: http://ntp.niehs.nih.gov/go/tr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070404/3ae15e1d/attachment.htm From ntpmail at list.niehs.nih.gov Tue Apr 10 13:11:50 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Apr 10 13:12:20 2007 Subject: NTP UPDATE: Updated Meeting Agenda - May Subcommittee Message-ID: An updated agenda has been posted for the NTP Technical Reports Review Subcommittee meeting to be held May 16-17, 2007. Isoeugenol (TR-551) will not be reviewed at this meeting. The agenda and additional information about this meeting may be found at: http://ntp.niehs.nih.gov/go/15833 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070410/cff4df43/attachment.htm From ntpmail at list.niehs.nih.gov Thu Apr 12 14:51:49 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Apr 12 14:52:20 2007 Subject: NTP UPDATE: Availability of Draft Technical Reports Message-ID: The NTP announces the availability of the Draft Technical Reports on cresols, cumene, ethinyl estradiol (multigeneration and carcinogenicity), formamide, propargyl alcohol, and sodium dichromate dihydrate that will be reviewed at the NTP Technical Reports Review Subcommittee Meeting on May 16-17, 2007 in Research Triangle Park. The reports can be obtained from the NTP website at http://ntp.niehs.nih.gov/go/28960. Additional information about the meeting is available at http://ntp.niehs.nih.gov/go/15833. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070412/a01e4d72/attachment.htm From ntpmail at list.niehs.nih.gov Mon Apr 16 15:00:39 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Apr 16 15:01:09 2007 Subject: NTP UPDATE: RoC announces review process for 12th Edition Message-ID: Today, NTP released of the final review process for preparation of the 12th Report on Carcinogens and announced its availability in the Federal Register. The review process is available at http://ntp.niehs.nih.gov/go/15208 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070416/9d99ad20/attachment.htm From ntpmail at list.niehs.nih.gov Mon Apr 16 16:02:56 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Apr 16 16:03:05 2007 Subject: NTP UPDATE: Updated NTP Testing Status Message-ID: NTP results & status information for all NTP studies has been updated; you may search testing status of agents using the following url: http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070416/eefaf7b5/attachment.htm From ntpmail at list.niehs.nih.gov Fri Apr 20 13:38:19 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Apr 20 13:38:50 2007 Subject: NTP UPDATE: Final NTP Genetically Modified Model Reports now available Message-ID: Final National Toxicology Program Genetically Modified Model Reports are now available for the following studies: GMM-06: Toxicology Studies of Sodium Bromate (CAS No. 7789-38-0) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenicity Studies of Sodium Bromate in Genetically Modified [B6.129-Trp53[tm1Brd] (N5) Haploinsufficient] Mice (Drinking Water Studies) GMM-10: Toxicology Study of Diispropylcarbodiimide (CAS No. 693-13-0) in Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Study of Diispropylcarbodiimide in Genetically Modified [B6.129-Trp53[tm1Brd] (N5) Haploinsufficient Mice (Dermal Studies) See URL: http://ntp.niehs.nih.gov/go/14367 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070420/1615ba39/attachment.htm From ntpmail at list.niehs.nih.gov Tue May 1 14:32:37 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue May 1 14:32:48 2007 Subject: NTP UPDATE: Technical Report on Dibromoacetic Acid now available Message-ID: The final TR-537, National Toxicology Program Toxicology and Carcinogenesis Studies of Dibromoacetic Acid (CAS No. 631-64-1) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) is now available. See URL: http://ntp.niehs.nih.gov/go/tr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070501/3b5fa444/attachment.htm From ntpmail at list.niehs.nih.gov Wed May 2 14:53:16 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed May 2 14:53:21 2007 Subject: NTP UPDATE: CERHR postpones meeting Message-ID: The NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the postponement of the Second Bisphenol A Expert Panel Meeting and extension of public comment period for the Interim Draft Expert Panel Report on Bisphenol A See Announcement: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=4DFAEDAB-F1F6-975E-7AC0B7 6516EB1201 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070502/30647e6d/attachment.htm From ntpmail at list.niehs.nih.gov Wed May 2 15:00:15 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed May 2 15:00:19 2007 Subject: NTP UPDATE: SACATM Meeting & Request for Comment Message-ID: The NTP Liaison and Scientific Review Office announces a meeting of the Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) and requests comments. The announcement and additional information may be found on the meeting page: http://ntp.niehs.nih.gov/go/7441 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070502/84a9ac64/attachment.htm From ntpmail at list.niehs.nih.gov Wed May 2 15:04:59 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed May 2 15:05:04 2007 Subject: NTP UPDATE: NICEATM announces availability of Draft 5-Year Plan Message-ID: The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces the availability of the Draft NICEATM-ICCVAM 5-Year Plan and Request for Public Comments; Announcement of a Town Meeting on the Draft NICEATM-ICCVAM 5-Year Plan. See Announcement: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=4E09B4C1-F1F6-975E-7D92C4 1D23B6E8CF -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070502/df5aeacd/attachment.htm From ntpmail at list.niehs.nih.gov Thu May 10 10:43:20 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu May 10 10:47:01 2007 Subject: NTP UPDATE: Federal Register Announcements Message-ID: The National Toxicology Program invites nominations of scientific experts to serve on expert panels for 12th Report on Carcinogens. See FR Notice: http://ntp.niehs.nih.gov/files/roc_72_fr_89.pdf The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces availability of the Peer Review Panel Report on Five In Vitro Pyrogen Test Methods and requests public comments. See FR Notice: http://iccvam.niehs.nih.gov/SuppDocs/FedDocs/FR/FR_E7_8896.pdf NICEATM announces request for data on the use of topical anesthetics and systemic analgesics for in vivo eye irritation testing. See FR Notice: http://iccvam.niehs.nih.gov/SuppDocs/FedDocs/FR/FR_E7_8898.pdf -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070510/1fa3143a/attachment.htm From ntpmail at list.niehs.nih.gov Tue May 15 14:41:01 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue May 15 14:41:31 2007 Subject: NTP UPDATE: June 22 NTP Board Meeting is announced Message-ID: The National Toxicology Program (NTP) Liaison and Scientific Review Office announces a meeting of the NTP Board of Scientific Counselors to be held on June 22, 2007. The Federal Register Notice and additional meeting information can be found at the following URL: http://ntp.niehs.nih.gov/go/165 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070515/cca47323/attachment.htm From ntpmail at list.niehs.nih.gov Thu May 17 14:23:14 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu May 17 14:23:44 2007 Subject: NTP UPDATE: NICEATM Murine Local Lymph Node Assay announcement Message-ID: National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM); the Murine Local Lymph Node Assay: Request for Comments, Nominations of Scientific Experts, and Submission of Data. See Federal Register Notice: http://ntp.niehs.nih.gov/files/72FR95_27815.pdf -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070517/9d90dd22/attachment.htm From ntpmail at list.niehs.nih.gov Tue May 22 09:17:01 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue May 22 09:17:35 2007 Subject: NTP UPDATE: Attend the June 11th Town Meeting on Draft NICETAM-ICCVAM Five Year-Plan In-Reply-To: Message-ID: Your comments and participation are encouraged as federal agencies look for new ways to reduce, refine and replace the use of animals in testing. The National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and the Interagency Coordinating Committee on The Validation of Alternative Methods (ICCVAM) invite you to attend a Town Meeting on June 11th from 1:00 to 5:00 PM at the William H. Natcher Conference Center, Room E, at NIH in Bethesda, MD to hear about their draft five-year plan and to provide members of the public opportunities for input. The ?Draft NICETAM-ICCVAM Five Year-Plan? available at http://iccvam.niehs.nih.gov/docs/5yearplan.htm addresses four key challenges: * Identify priority areas and methods to reduce and replace animal use and reduce animal pain and distress * Incorporate advances in science and technologies to develop new test methods and approaches * Proactively communicate the use of alternative test methods to government and non-government stakeholders * Develop and strengthen partnerships to promote research, development, translation, and validation activities for alternative test methods Attend the Monday, June 11th Town Meeting: Please complete the online registration by June 7th at the NICEATM?ICCVAM website http://iccvam.niehs.nih.gov/meetings/5YPlanTM/townmtg.htm; OR Phone NICEATM at 919-541-2384 Email at niceatm@niehs.nih.gov. Provide Written Comments: Please submit written comments electronically at http://iccvam.niehs.nih.gov/contact/FR_pubcomment.htm Comments can also be submitted by e-mail to 5yearplan@niehs.nih.gov Please include appropriate contact information (name, affiliation, mailing address, phone, fax, e-mail, and sponsoring organization, if applicable). Reasonable Accommodation Needs: Persons needing special assistance, such as sign language interpretation or other reasonable accommodation in order to attend, should contact 919?541?2475 voice, 919?541?4644 TTY (text telephone), through the Federal TTY Relay System at 800?877?8339, or send e-mail to niehsoeeo@niehs.nih.gov. Requests should be made at least 7 days in advance of the meeting. ICCVAM, a permanent interagency committee administered by the National Institute of Environmental Health Sciences under NICEATM, is composed of members designated by the heads of 15 federal agencies. ICCVAM was created under the ICCVAM Authorization Act of 2000 (42 U.S.C 285l-3). -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070522/b9b981b1/attachment.htm From ntpmail at list.niehs.nih.gov Tue Jun 5 12:35:44 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Jun 5 12:35:53 2007 Subject: NTP UPDATE: Final NTP Genetically Modified Model Reports now available Message-ID: Final National Toxicology Program Genetically Modified Model Reports are now available for the following studies: GMM-05: Toxicology Studies of Bromodichloromethane (CAS No. 75-27-4) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal, Drinking Water, and Gavage Studies) and Carcinogenicity Studies of Bromodichloromethane in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Drinking Water and Gavage Studies) GMM-11: Toxicology Studies of Dichloroacetic Acid (CAS No. 79-43-6) in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenicity Studies of Dichloroacetic Acid in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Drinking Water Studies) See URL: http://ntp.niehs.nih.gov/go/14367 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070605/3e82e577/attachment.htm From ntpmail at list.niehs.nih.gov Mon Jun 11 09:02:32 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jun 11 09:03:02 2007 Subject: NTP UPDATE: Videocast Information for June 11th Town Meeting on Draft NICETAM-ICCVAM Five Year-Plan Message-ID: The National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and the Interagency Coordinating Committee on The Validation of Alternative Methods (ICCVAM) will hold a Town Meeting today, Monday, June 11, from 1:00 to 5:00 PM at the William H. Natcher Conference Center, Room E, at NIH in Bethesda, MD to provide members of the public opportunities for input on their draft five-year plan. The ?Draft NICETAM-ICCVAM Five Year-Plan? available at http://iccvam.niehs.nih.gov/docs/5yearplan.htm addresses four key challenges: * Identify priority areas and methods to reduce and replace animal use and reduce animal pain and distress * Incorporate advances in science and technologies to develop new test methods and approaches * Proactively communicate the use of alternative test methods to government and non-government stakeholders * Develop and strengthen partnerships to promote research, development, translation, and validation activities for alternative test methods The videocast of this meeting will be available under ?Today?s Events? -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070611/623da1d4/attachment.htm From ntpmail at list.niehs.nih.gov Tue Jun 12 12:06:35 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Jun 12 12:07:09 2007 Subject: NTP UPDATE: NICEATM request for submission of relevant data Message-ID: The National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) requests ocular irritancy test data from human, rabbit, and in vitro studies using standardized testing methods. See Federal Register notice at URL: http://ntp.niehs.nih.gov/index.cfm?objectid=209E178E-F1F6-975E-7C10EE2744768 79B -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070612/b94726b2/attachment.htm From ntpmail at list.niehs.nih.gov Wed Jun 13 10:23:30 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Jun 13 10:24:02 2007 Subject: NTP UPDATE: Editor-in-chief, EHP In-Reply-To: <8BB67CD070A6EE479378FBE1CEB7947802052F8D@NIHCESMLBX6.nih.gov> Message-ID: A vacancy for the position of Editor-in-Chief for Environmental Health Perspectives located at the National Institute of Environmental Health Sciences (NIEHS) is currently being advertised and is open to all qualified individuals. Please see the job posting at the link below: http://jobsearch.usajobs.opm.gov/getjob.asp?JobID=58175449=2007%2D05%2D30+07 %3A45%3A59=0=18015=Y=rv=d=3876=0=Y.x=61.y=8 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070613/e0259af0/attachment.htm From ntpmail at list.niehs.nih.gov Fri Jun 15 11:39:51 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Jun 15 11:40:21 2007 Subject: NTP UPDATE: New NTP Associate Director Named In-Reply-To: Message-ID: Today the National Toxicology Program announces the appointment of Dr. John Bucher as the new associate director. See Press Release: http://ntp.niehs.nih.gov/files/NTPAssociate_Directorfinal.pdf -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070615/2b992ca1/attachment.htm From ntpmail at list.niehs.nih.gov Fri Jun 15 15:24:11 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Jun 15 15:25:55 2007 Subject: NTP UPDATE: CERHR announces 2nd BPA Expert Panel Meeting Message-ID: The NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) announces the second Bisphenol A Expert Panel meeting August 6-8, 2007 and requests comments. More information available on the meeting page web link: http://cerhr.niehs.nih.gov/chemicals/bisphenol/bisphenol-mtg.html -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070615/94fc844a/attachment.htm From ntpmail at list.niehs.nih.gov Tue Jun 19 12:12:22 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Jun 19 12:12:55 2007 Subject: NTP UPDATE: Biomarkers applications and technologies workshop is announced In-Reply-To: Message-ID: Skipped content of type multipart/alternative-------------- next part -------------- A non-text attachment was scrubbed... Name: LISA Workshop 2007.pdf Type: application/octet-stream Size: 30340 bytes Desc: not available Url : http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070619/2f0d2baa/LISAWorkshop2007.obj From ntpmail at list.niehs.nih.gov Fri Jul 13 08:25:07 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Jul 13 08:25:37 2007 Subject: NTP UPDATE: EHP Message-ID: July 12, 2007 Dear Colleague, We want to take this opportunity to provide you some updated information regarding our scientific journal, Environmental Health Perspectives (EHP), and to thank you for your expressed confidence in this publication. We are glad to know that you highly value EHP as a scientific resource, and as an effective educational and news resource on environmental health topics. We assure you that the entire leadership team at the National Institute of Environmental Health Sciences (NIEHS) is fully committed to publishing EHP and to providing the support necessary to sustain EHP as a leading journal. We are pleased to let you know that the EHP impact factor continues to rise, increasing from 3.929 in 2004 to 5.861 in 2007. According to Journal Citation Reports Science Edition, EHP ranks first among 144 Environmental Sciences journals and third among 98 Public, Environmental and Occupational Health journals. The NIEHS is actively recruiting candidates to serve as the journal?s new Editor-in-Chief. This position will be a full-time federal appointment, as it has been in the past. Additionally, technological support for the journal has been upgraded. A web-based manuscript management system now being implemented will greatly enhance the scientific peer-review and publication processes. EHP has always been produced with the assistance of a publishing services contractor. The current contract will expire this year, and the National Library of Medicine has issued a new contract solicitation on behalf of the NIEHS. The solicitation can be found on the Federal Business Opportunities website, www.fbo.gov . As specified in the contract solicitation, EHP will remain an ?open-access? publication, available free of charge on-line at www.ehponline.org . EHP will also continue to be produced as a printed journal available through subscription. Since 1972, the NIEHS has published EHP to provide a worldwide forum for research and education on environmental health sciences. The NIEHS is proud to continue its full support for the future success of EHP. Sincerely, William Martin, M.D. Associate Director National Institute of Environmental Health Sciences National Institutes of Health Samuel Wilson, M.D. Deputy Director National Institute of Environmental Health Sciences National Institutes of Health -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070713/c719e4fc/attachment.htm From ntpmail at list.niehs.nih.gov Mon Jul 16 10:29:07 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Jul 16 10:29:36 2007 Subject: NTP UPDATE: NTP News Update - July 2007 Message-ID: The NTP News Update for July 2007 is now available at URL: http://ntp.niehs.nih.gov/go/29068 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070716/91e54c02/attachment.htm From ntpmail at list.niehs.nih.gov Thu Jul 19 14:53:47 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Jul 19 14:54:03 2007 Subject: NTP UPDATE: Correction to NTP News Update for July Message-ID: The NTP News Update for July 2007 sent on July 16, listed the date for the Second Meeting of the CERHR Expert Panel on Bisphenol A (pages 2 & 4) as August 6-8, 2008 ? the meeting will be held August 6-8, 2007. The corrected News Update can be found at URL: http://ntp.niehs.nih.gov/go/29068 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070719/d015cedb/attachment.htm From ntpmail at list.niehs.nih.gov Fri Jul 27 15:29:46 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Jul 27 15:30:16 2007 Subject: NTP UPDATE: Update on NTP Activities Message-ID: Update on NTP Activities Over the past few months, the National Toxicology Program (NTP) has undertaken a number of activities to address issues related to conflicts of interest (COI) and to ensure continued public confidence in its work. These included an independent review of its contracts for potential COI, development of a strong clause about COI for adding to NTP contracts, and an audit to assess the objectivity of information in draft reports prepared on the reproductive and developmental toxicity of bisphenol A (BPA). NTP would like to update you on these activities. Review of NTP contracts A working group of the NTP Board of Scientific Counselors conducted a review of NTP contracts to (1) assess potential COI, (2) develop recommendations appropriate for reducing the potential for conflicts to occur, and (3) address mechanisms for mitigating any current or future COI. The working group reviewed NTP contracts, information on contract performance provided by NTP staff, and information on policies and practices concerning COI provided by selected NTP contractors. The working group report was presented to the NTP Board of Scientific Counselors at its meeting on June 22, 2007, and following discussion, accepted unanimously without revision. The working group found no evidence of actual or apparent COI in its review of NTP contracts; however, it did recommend a number of best practices and areas where improvements could be made. The working group report is posted on the NTP web site (http://ntp.niehs.nih.gov under ?Latest News?). COI clause for NTP contracts A clause that specifically addresses contractor COI was developed and is being added to all NTP contracts. This action complements the review of NTP contracts by the NTP Board of Scientific Counselors Working Group, as noted above (see BSC Working Group report, Attachment 9, available at http://ntp.niehs.nih.gov under ?Latest News?). Audit of draft BPA reports The NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) conducts rigorous independent scientific evaluations to assess risk to human reproduction and development caused by environmental agents, such as bisphenol A, a chemical currently under review. In response to concerns raised about Sciences International, Inc. (SI), the former CERHR contractor (see March 2007 and April 2007 statements available at http://cerhr.niehs.nih.gov under ?CERHR News?), NTP committed to a review of the contractor?s services to CERHR. As part of this review, NTP conducted an audit of two key activities carried out by SI: (1) selection of literature relevant for review by the expert panel on BPA and (2) incorporation of input from expert panel members into draft reports. NTP found that SI made available to the expert panel members for their consideration appropriate references relevant to the BPA evaluation. NTP also found that SI reliably made changes to the draft reports requested by the expert panel. Based upon this audit, NTP concluded that the draft expert panel reports are useful for the BPA evaluation. The audit report is posted on the NTP (http://ntp.niehs.nih.gov under ?Latest News?) and CERHR (http://cerhr.niehs.nih.gov under ?CERHR News?) web sites. Second BPA Expert Panel Meeting The second BPA expert panel meeting is scheduled for August 6-8, 2007, at the Hilton Alexandria Old Town in Alexandria, Virginia. Details about the meeting are available on the CERHR web site for BPA ( http://cerhr.niehs.nih.gov/chemicals/bisphenol/bisphenol-mtg.html ). -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070727/20cbd7eb/attachment.htm From ntpmail at list.niehs.nih.gov Wed Aug 1 15:28:48 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Aug 1 15:29:14 2007 Subject: NTP UPDATE: RoC announces expert panel meeting on draft background documents Message-ID: The NTP Report on Carcinogens (RoC) announces the availability of draft background documents on captafol and ortho-nitrotoluene, requests public comment on these draft documents, and announces the captafol and ortho-nitrotoluene expert panel meeting. See the Federal Register notice, draft background documents and meeting information available on the NTP website: http://ntp.niehs.nih.gov/go/29679 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070801/06aa4d2f/attachment.htm From ntpmail at list.niehs.nih.gov Fri Aug 10 09:17:54 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Aug 10 09:18:03 2007 Subject: NTP UPDATE: Availability of Pathology Data Tables for NTP Studies Message-ID: The NTP Pathology Working Group has reviewed the following study and final pathology tables have been generated for beta-Myrcene (mice) and are available at the NTP website URL: http://ntp.niehs.nih.gov/go/29763 The complete set of data tables (body weight, clinical observations, survival, and pathology) for studies planned for peer review are available on the NTP website at URL: http://ntp.niehs.nih.gov/go/peerreview -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070810/58737cb3/attachment.htm From ntpmail at list.niehs.nih.gov Fri Aug 10 11:53:59 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Aug 10 11:54:29 2007 Subject: NTP UPDATE: CERHR expert panel on bisphenol A Message-ID: The NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) held the second public meeting of the expert panel on bisphenol A on August 6-8, 2007, in Alexandria, VA. The panel continued its review and assessment of the scientific literature on the potential reproductive and developmental hazards of bisphenol A. The meeting summary, which includes the panel?s conclusions regarding bisphenol A, is available on the NTP website at http://ntp.niehs.nih.gov (see ?Latest News?). The expert panel report will now be prepared for publication and made available to the public for comment. NTP will announce availability of the report through the Federal Register and the NTP email listserv. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070810/caedcc86/attachment.htm From ntpmail at list.niehs.nih.gov Mon Aug 13 09:20:45 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Aug 13 09:20:54 2007 Subject: NTP UPDATE: Updated NTP Testing Status Message-ID: NTP results & status information for all NTP studies has been updated; you may search testing status of agents using the following url: http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070813/156af763/attachment.htm From ntpmail at list.niehs.nih.gov Thu Aug 16 14:09:53 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Aug 16 14:10:01 2007 Subject: NTP UPDATE: Dimethylaminopropyl Chloride, Hydrochloride Toxicity Report available Message-ID: The final, TOX-75, National Toxicology Program Toxicity Studies of Dimethylaminopropyl Chloride, Hydrochloride (CAS No. 5407-04-5) administered by gavage to F344/N rats and B6C3F1 mice is now available. See URL: http://ntp.niehs.nih.gov/go/14372 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070816/bf57a920/attachment.htm From ntpmail at list.niehs.nih.gov Thu Aug 23 14:18:54 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Aug 23 14:19:23 2007 Subject: NTP UPDATE: NTP Pathology Tables for 1,2-dibromo-2,4-dicyanobutane Message-ID: The pathology tables for 1,2-Dibromo-2,4-dicyanobutane have been updated and are available at the NTP website URL: http://ntp.niehs.nih.gov/go/28622 The complete set of data tables (body weight, clinical observations, survival, and pathology) for studies planned for peer review are available on the NTP website at URL: http://ntp.niehs.nih.gov/go/peerreview -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070823/dd01c2da/attachment.htm From ntpmail at list.niehs.nih.gov Fri Aug 24 14:40:27 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Aug 24 14:40:35 2007 Subject: NTP UPDATE: Udated pathology tables for Dibromoacetonitrile now available Message-ID: The pathology tables for Dibromoacetonitrile have been updated and are available at the NTP website URL: http://ntp.niehs.nih.gov/go/28388 The complete set of data tables (body weight, clinical observations, survival, and pathology) for studies planned for peer review are available on the NTP website at URL: http://ntp.niehs.nih.gov/go/peerreview -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070824/dd56a370/attachment.htm From ntpmail at list.niehs.nih.gov Thu Sep 6 14:48:32 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Sep 6 14:49:02 2007 Subject: NTP UPDATE: Request for Information (RFI): Genetic Variation and the Basis for Individual Susceptibility to Environmental Toxicant Associated Disease Message-ID: The NTP is currently soliciting information from the extramural and intramural research communities on the strategies, resources, and tools necessary to enable this cooperative research program on genetic variation and individual susceptibility to environmental toxicant exposure and associated polygenic diseases to progress. The Request for Information (RFI): Genetic variation and the basis for individual susceptibility to environmental toxicant associated disease was published today in the NIH Guide for Grants and Contracts ? see URL: http://grants.nih.gov/grants/guide/notice-files/NOT-ES-07-009.html You may respond online to any or all of the questions on the RFI by October 14, 2007 at URL: http://ntp.niehs.nih.gov/go/32130 You may visit the Host Susceptibility Program website at: http://ntp.niehs.nih.gov/go/32132 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070906/fa9db528/attachment.htm From ntpmail at list.niehs.nih.gov Thu Sep 6 14:54:32 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Sep 6 14:54:42 2007 Subject: NTP UPDATE: New Issue of eFactor is now on-line Message-ID: The September issue of eFactor is now featured on the new NIEHS Website at: http://www.niehs.nih.gov/news/newsletter/index.cfm Highlights include: Trainees Meet NIH Training and Education Director Sharon Milgram Bisphenol A in the News Extramural Networks Symposium Scientific Director Lecture Series: Evan Simpson and Rudy Juliano NIEHS Extramural Funds Novel Approach to Autism Research Reports on Lectures by Karen Adelman, Redford Williams and Ken Olden Mouse Haplotype Published in Nature September Distinguished Lecturer Susan Cole Extramural Update Extramural/Intramural Papers of the Month Delta Summer Day Camp for Durham Kids Softball Showdown on Friends and Family Day Calendar of Upcoming Events The eFactor welcomes ideas for stories about news items, scientific findings and employee events. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070906/fa243c73/attachment.htm From ntpmail at list.niehs.nih.gov Wed Sep 12 13:58:56 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Sep 12 13:59:26 2007 Subject: NTP UPDATE: Draft murine LLNA performance standards Message-ID: In today?s Federal Register, the National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces the draft performance standards for the murine local lymph node assay and requests comments. View the announcement: http://ntp.niehs.nih.gov/files/LLNA_72_FR_176.pdf -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070912/95f5c6fd/attachment.htm From ntpmail at list.niehs.nih.gov Fri Sep 21 14:24:11 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Sep 21 14:24:21 2007 Subject: NTP UPDATE: Updated NTP Testing Status Message-ID: NTP results & status information for all NTP studies has been updated; you may search testing status of agents using the following url: http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070921/1f091f6e/attachment.htm From ntpmail at list.niehs.nih.gov Tue Sep 25 15:19:10 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Sep 25 15:19:35 2007 Subject: NTP UPDATE: NTP pathology tables for beta-myrcene Message-ID: The pathology tables for beta-Myrcene have been updated and are available at the NTP website URL: http://ntp.niehs.nih.gov/go/32145 The complete set of data tables (body weight, clinical observations, survival, and pathology) for studies planned for peer review are available on the NTP website at URL: http://ntp.niehs.nih.gov/go/peerreview -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20070925/bb7afed9/attachment.htm From ntpmail at list.niehs.nih.gov Mon Oct 1 13:46:36 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Oct 1 13:47:09 2007 Subject: NTP UPDATE: October eFactor Message-ID: The October issue of eFactor is now featured on the new NIEHS Website at: http://www.niehs.nih.gov/news/newsletter/index.cfm Highlights include: NIEHS Advisory Council Meeting/Reports on Trans-NIH Initiatives Offsite Conferences on Endocrine Disruptors and the Built Environment Profile ? New Air-Sampling Robot on Red Tide Beach Reports on Lectures by Susan Cole, Donald Anderson, Shuk-Mei Ho, Dale Ramsden and Thomas Arcury Extramural Update; Papers of the Month Jerry Phelps Peddles from Paris to the Coast of France ? and Back Calendar of Upcoming Events The eFactor welcomes ideas for stories about news items, scientific findings and employee events. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071001/916288fd/attachment.htm From ntpmail at list.niehs.nih.gov Tue Oct 2 14:17:37 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Oct 2 14:17:47 2007 Subject: NTP UPDATE: NTP News Update - October 2007 Message-ID: The NTP News Update for October 2007 is now available at URL: http://ntp.niehs.nih.gov/go/29068 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071002/8fa14eba/attachment.htm From ntpmail at list.niehs.nih.gov Wed Oct 3 14:02:52 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Oct 3 14:03:23 2007 Subject: NTP UPDATE: NTP requests information for Host Susceptibility Program Message-ID: The National Toxicology Program (NTP) is developing the Host Susceptibility Program (HSP), a new research program, to identify and functionally validate genes associated with environmental exposure. This program will make available NTP expertise and resources to investigate the genetic basis for population-level differences in susceptibility to environmental toxicants and/or disease based upon gene and environment interactions. Through a Request for Information (RFI), extramural and intramural scientists are invited and encouraged to provide information and comment relevant to this proposed programmatic research approach in order to help guide further development and refinement of the goals of the NTP HSP. Information on this initiative can be submitted electronically through the HSP Request for Information Web site at: ( http://ntp.niehs.nih.gov/go/32130 ). Federal Register Notice: http://ntp.niehs.nih.gov/index.cfm?objectid=6669E0EE-F1F6-975E-7143B489FF38F 631 For more information about the NTP Host Susceptibility Program visit: http://ntp.niehs.nih.gov/go/32132 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071003/4fe662b9/attachment.htm From ntpmail at list.niehs.nih.gov Wed Oct 10 13:48:16 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Oct 10 13:48:46 2007 Subject: NTP UPDATE: NAS Report Offers New Tools to Assess Health Risks from Chemicals In-Reply-To: Message-ID: Today, the National Academies of Sciences (NAS) announced release ( http://www.nationalacademies.org/morenews/20071009.html ) of the report from NAS National Research Council entitled ?Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment.? NIEHS commissioned the NAS report. > NAS Report Offers New Tools to Assess Health Risks from Chemicals > > Determining how thousands of chemicals found in the environment may be > interacting with the genes in your body to cause disease is becoming easier > because of a new field of science called toxicogenomics. A new report issued > today by the National Academies of Sciences (NAS) recognizes the importance of > toxicogenomics in predicting effects on human health and recommends the > integration of toxicogenomics into regulatory decision making. The NAS report > was commissioned by the National Institute of Environmental Health Sciences > (NIEHS) part of the National Institutes of Health (NIH) and a leader in the > development of toxicogenomic technologies. > > Toxicogenomic technologies provide tools to better understand the mechanisms > through which environmental agents initiate and advance disease processes. > They can also provide important information to help identify individuals that > are more susceptible to disease risks posed by certain environmental agents > than the general population. > > ?Using toxicogenomic technologies will open the door for public health > decision makers who need to decide in a timely and accurate manner what > chemicals are safe and which ones are not,? says Christopher Portier, Ph.D., > Associate Director, NIEHS and Director, Office of Risk Assessment Research. > > The report from the NAS National Research Council (NRC) entitled ?Applications > of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment? > states that the technological hurdles that could have limited the > reproducibility of data from toxicogenomic technologies have been resolved and > recommends ways for the field to move forward. > > ?NIH and others have invested in the development of these tools and have > already tackled many of the tough technical questions. We are now ready to > move to the next phase of technology development, refined standardization and > validation, so these tools can be even more useful to regulatory agencies,? > says Portier. > > ?The NIEHS and NTP have been steadily increasing the use of toxicogenomic and > other technologies derived from the molecular biology revolution,? said Samuel > H. Wilson, M.D., NIEHS Acting Director. The research and initiatives > supported through the National Center for Toxicogenomics and the > Toxicogenomics Research Consortium, for example, were at the forefront of > these technologies and were leaders in the development of many of the > standards for quality and reproducibility that are used today. > > The report, which was prepared by a panel of 16 scientists assembled by the > NRC, provides a broad overview of the potential benefits arising from > toxicogenomic technologies, describes challenges regarding use of new > technologies, and provides 14 recommendations to achieve the potential > benefits of these technologies. > > To read or order the ?Applications of Toxicogenomic Technologies to Predictive > Toxicology and Assessment? report, please visit > http://books.nap.edu/catalog.php?record_id=12037. > > > The primary mission of the National Institute of Environmental Health Sciences > ( http://www.niehs.nih.gov/ ) (NIEHS), one of 27 Institutes and Centers at the > National Institutes of Health, is to reduce the burden of human illness and > disability by understanding how the environment influences the development and > progression of human disease. For additional information, visit the NIEHS Web > site at http://www.niehs.nih.gov/ > > The National Toxicology Program (NTP) is an interagency program established in > 1978 by the Secretary of Health, Education and Welfare, predecessor of the > U.S. Department of Health and Human Services. The program was created as a > cooperative effort to coordinate toxicology testing programs within the > federal government, strengthen the science base in toxicology, develop and > validate improved testing methods, and provide information about potentially > toxic chemicals to health, regulatory, and research agencies, scientific and > medical communities, and the public. > > The National Institutes of Health (NIH) - The Nation?s Medical Research Agency > - includes 27 Institutes and Centers and is a component of the U. S. > Department of Health and Human Services. It is the primary federal agency for > conducting and supporting basic, clinical, and translational medical research, > and it investigates the causes, treatments, and cures for both common and rare > diseases. For more information about NIH and its programs, visit > http://www.nih.gov/ > > NIH News Release: Tuesday, October 9, 2007 > -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071010/ec7d31d4/attachment.htm From ntpmail at list.niehs.nih.gov Mon Oct 15 14:45:34 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Oct 15 14:46:03 2007 Subject: NTP UPDATE: NTP requests information for Host Susceptibility Program Message-ID: Second Announcement As previously announced, The National Toxicology Program (NTP) is developing the Host Susceptibility Program (HSP), a new research program, to identify and functionally validate genes associated with environmental exposure. This program will make available NTP expertise and resources to investigate the genetic basis for population-level differences in susceptibility to environmental toxicants and/or disease based upon gene and environment interactions. Through a Request for Information (RFI), extramural and intramural scientists are invited and encouraged to provide information and comment relevant to this proposed programmatic research approach in order to help guide further development and refinement of the goals of the NTP HSP. The deadline for receipt of the information is 31 October 2007. Information on this initiative can be submitted electronically through the HSP Request for Information Web site at: http://ntp.niehs.nih.gov/go/32130 Federal Register Notice: http://ntp.niehs.nih.gov/index.cfm?objectid=6669E0EE-F1F6-975E-7143B489FF38F 631 For more information about the NTP Host Susceptibility Program visit: http://ntp.niehs.nih.gov/go/32132 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071015/54bfb76d/attachment.htm From ntpmail at list.niehs.nih.gov Thu Oct 18 13:32:46 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Oct 18 13:33:16 2007 Subject: NTP UPDATE: NTP announces December board meeting Message-ID: The National Toxicology Program (NTP) announces the December 6, 2007 meeting of the NTP Board of Scientific Counselors and requests comments. Learn more about the meeting: http://ntp.niehs.nih.gov/go/165 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071018/d987b401/attachment.htm From ntpmail at list.niehs.nih.gov Mon Oct 29 09:49:16 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Oct 29 09:49:25 2007 Subject: NTP UPDATE: NTP Updated Testing Status Message-ID: NTP results & status information for all NTP studies has been updated; you may search testing status of agents using the following url: http://ntp.niehs.nih.gov:8080/index.html?col=010stat > The updated NTP Management Status report for carcinogenicity/toxicity studies is available at the following url: http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071029/e7a0325d/attachment.htm From ntpmail at list.niehs.nih.gov Thu Nov 1 12:39:19 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Nov 1 12:39:50 2007 Subject: NTP UPDATE: November Environmental Factor now online Message-ID: The November issue of Environmental Factor is now online at: http://www.niehs.nih.gov/news/newsletter/index.cfm Highlights include: Mason Honored for Lifetime Achievement in Free Radical Biology Wilson Speaks at Genome Stability Meeting/Trainee Research Highlighted Meet Sharon Hrynkow, New NIEHS Associate Director Distinguished Lecturer Andrew Marks on Calcium Regulation Sister Study Advisory Meeting IRB Town Meeting Hispanic Heritage Month Scientific Lectures National Postdoc Executive Director Visits Superfund Research on Arsenic, Phytoremediation Intramural and Extramural Papers of the Month Disability Awareness Month Speaker And More? -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071101/df962e41/attachment.htm From ntpmail at list.niehs.nih.gov Wed Nov 7 14:36:24 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Nov 7 14:36:54 2007 Subject: NTP UPDATE: Dr. Ron Melnick Earns Rall Award for Environmental Health Advocacy Message-ID: For his outstanding contributions to public health through science-based advocacy, Ronald L. Melnick, PhD, received the 2007 David P. Rall Award for Advocacy in Public Health at the American Public Health Association (APHA) 135th Annual Meeting & Exposition. Read the full announcement: http://ntp.niehs.nih.gov/files/Melnick.pdf -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071107/23627f3b/attachment.htm From ntpmail at list.niehs.nih.gov Tue Nov 13 15:43:42 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Nov 13 15:43:51 2007 Subject: NTP UPDATE: RoC announces expert panel meeting on draft background documents Message-ID: The NTP Report on Carcinogens (RoC) announces the availability of draft background documents on aristolochic acid related exposures (2 candidate substances) and riddelliine, requests public comment on these draft documents, and announces the aristolochic acid related exposures and riddelliine expert panel meeting. See the Federal Register notice, draft background documents and meeting information available on the NTP website: http://ntp.niehs.nih.gov/go/29679 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071113/6d8c292c/attachment.htm From ntpmail at list.niehs.nih.gov Mon Nov 19 13:56:05 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Nov 19 13:56:23 2007 Subject: NTP UPDATE: NTP pathology tables for bis(2-Chloroethoxy)methane Message-ID: The pathology tables for bis(2-Chloroethoxy)methane (rats only) have been updated and are available at the NTP website URL: http://ntp.niehs.nih.gov/go/32277 The complete set of data tables (body weight, clinical observations, survival, and pathology) for studies planned for peer review are available on the NTP website at URL: http://ntp.niehs.nih.gov/go/peerreview -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071119/f4ddbe46/attachment.htm From ntpmail at list.niehs.nih.gov Mon Nov 26 10:33:07 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Nov 26 10:33:37 2007 Subject: NTP UPDATE: NICEATM announces availability of report and background review documents Message-ID: In today?s Federal Register, the National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces the availability of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) Test Method Evaluation Report on In Vitro Ocular Toxicity Test Methods for Identifying Severe Irritants and Corrosives and Final In Vitro Ocular Test Method Background Review Documents; Notice of Transmittal of ICCVAM Test Method Recommendations to Federal Agencies. View the announcement: http://ntp.niehs.nih.gov/files/NICEATM_72_FR_226.pdf -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071126/2ecdfa8e/attachment.htm From ntpmail at list.niehs.nih.gov Tue Nov 27 14:23:43 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Tue Nov 27 14:23:52 2007 Subject: NTP UPDATE: Genetically Modified Model Report on Benzene now available Message-ID: The final, GMM-08, National Toxicology Program Genetically Modified Model Report on the Toxicology and Carcinogenesis Study of Benzene (CAS No. 71-43-2) administered by gavage to genetically modified Haploinsufficient p16[Inka4a]/p19[Arf] mice is now available. See URL: http://ntp.niehs.nih.gov/go/28483 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071127/0ed9ca22/attachment.htm From ntpmail at list.niehs.nih.gov Wed Nov 28 11:56:30 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Wed Nov 28 11:56:59 2007 Subject: NTP UPDATE: Updates to the NTP Website Message-ID: The following final reports are now available on the NTP website: > > GMM-9: National Toxicology Program Genetically Modified Model Report on the > Toxicology Studies of Dicyclohexylcarbodiimide (CAS No. 538-75-0) in F344/N > Rats, B6C3F1 Mice, and Genetically Modified (FVB Tg.AC Hemizygous) Mice and > Carcinogenicity Study of Dicyclohexylcarbodiimide in Genetically Modified > [B6.129-Trp53[tm1Brd] (N5) Haploinsufficient] Mice (Dermal Studies) > See URL: http://ntp.niehs.nih.gov/go/28490 > > TOX-62: National Toxicology Program Toxicity Report on the Toxicity Studies of > Wy-14,643 (CAS No. 50892-23-4) administered in Feed to Male Sprague-Dawley > Rats, B6C3F1 Mice, and Syrian Hamsters > See URL: http://ntp.niehs.nih.gov/go/32492 > * Updated Testing Status: > NTP results & status information for all NTP studies has been updated; you may > search testing status of agents using the following url: > http://ntp.niehs.nih.gov:8080/index.html?col=010stat > > The updated NTP Management Status report for carcinogenicity/toxicity studies > is available at the following url: > http://ntp.niehs.nih.gov/go/msr > -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071128/a949d3a1/attachment.htm From ntpmail at list.niehs.nih.gov Fri Nov 30 13:57:02 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Nov 30 13:57:41 2007 Subject: NTP UPDATE: Final expert panel report for bisphenol A evaluation is now available; request for comments Message-ID: In today?s Federal Register, NTP-CERHR announced the availability of the final expert panel report for bisphenol A (BPA) evaluation and request for public comments. View the FR notice at URL: http://ntp.niehs.nih.gov/files/BPA_Fnl_72_FR_230.pdf BPA Final Expert Panel Report ? see URL: http://cerhr.niehs.nih.gov/chemicals/bisphenol/BPAFinalEPVF112607.pdf BPA Evaluation page ? see URL: http://cerhr.niehs.nih.gov/chemicals/bisphenol/bisphenol-eval.html -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071130/2dc7b242/attachment.htm From ntpmail at list.niehs.nih.gov Mon Dec 3 15:13:28 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Mon Dec 3 15:13:57 2007 Subject: NTP UPDATE: December Environmental Factor now online Message-ID: The December Issue of the Environmental Factor is now online at: http://www.niehs.nih.gov/news/newsletter/index.cfm Highlights include: Aging Symposium Features NIEHS and NIA Scientists ONES Grantee Honored at White House Science Day Honors Trainees and Investigators Summer Intern Joins Mentor at TIES Bioinformatics/Genomics Conference Melnick Gets APHA Rall Award Kastan Delivers Falk Lecture GEMS Turns 25 at Fall Meeting Superfund Grantee Di Giulio Speaks Gene Expression and Acetaminophen OD New Editor-In-Chief for EHP Suk Leads NIEHS Global Health Delegation in Asia Friedberg to Give Distinguished Lecture Native American Heritage Event Features Cherokee Historian Wilson Kicks Off Mix and Mingle Series O?Fallon Runs and Rides in World Competition -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071203/b4b885f4/attachment.htm From ntpmail at list.niehs.nih.gov Thu Dec 13 10:49:47 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Thu Dec 13 10:50:19 2007 Subject: NTP UPDATE: NTP announces February BSC Technical Report Review Subcommittee Meeting Message-ID: In today?s Federal Register: The National Toxicology Program (NTP) Office of Liaison, Policy and Review announces the February 27-28, 2008 meeting of the NTP Board of Scientific Counselors Technical Reports Review Subcommittee and requests comments. View the Federal Register notice: http://ntp.niehs.nih.gov/files/TRRS_72_FR_239.pdf Meeting Page: http://ntp.niehs.nih.gov/mtg?date=20080127&meeting=TRRS -------------- next part -------------- An HTML attachment was scrubbed... URL: http://list.niehs.nih.gov/pipermail/ntpmail/attachments/20071213/87a0c70b/attachment.htm From ntpmail at list.niehs.nih.gov Fri Dec 21 14:00:25 2007 From: ntpmail at list.niehs.nih.gov (ntpmail@list.niehs.nih.gov) Date: Fri Dec 21 14:00:31 2007 Subject: NTP UPDATE: News from the NTP Message-ID: * In today?s Federal Register > The NTP Interagency Center for the Evaluation of Alternative Toxicological > Methods (NICEATM); Interagency Coordinating Committee on the Validation of > Alternative Methods (ICCVAM): Ten-Year Anniversary Symposium nad Five-Year > Plan ? announcement of public symposium and availability of document. > > Federal Register Notice URL: > http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=FCF6EDFF-F1F6-975E-7F04C92D > 3F08ED25 > > Meeting page: > http://iccvam.niehs.nih.gov/meetings/10thAnnivSymp/10thAnnivSymp.htm * Updated Testing Status: > NTP results & status information for all NTP studies has been updated; you may > search testing status of agents using the following url: > http://ntp.niehs.nih.gov:8080/index.html?col=010stat > > The updated NTP Management Status report for carcinogenicity/toxicity studies > is available at the following url: > http://ntp.niehs.nih.gov/go/msr -------------- next part -------------- An HTML attachment was scrubbed... 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