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Index of Cleared Science Reviews

Index for Triforine (Pc Code 107901)

March 23, 1972. Review. 3 Page(s).
J.A. Shaughnessy.
Preliminary Evaluation of Temp. Permit
for NEW CHEMICAL, CA 70203 on Roses
Submitted by Cela GMBH (Germany)
c/o EM Laboratories on 2-18-72
279-EXP-50G.

November 7, 1972. Review. 5 Page(s).
J. A. Shaughnessy.
Preliminary Evaluation of New Chemical
Temp. Permit - Funginex - Submitted by
EM Labs (Cela-Merck) 2-18-72, 3-1-72,
5-1-72 and 9-12-72 (later). Manufacturing process info
on page 2 and product impurity info on page 3 not included.

January 10, 1975. Review. 8 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
Environmental Chemistry Review for... (Triforine)
Reg. No. 279-EOON. F.M.C. Corp. Submitted 10-31-74.

February 26, 1975. Review. 18 Page(s).
Robert Coberly. Toxicology Branch.
Cela W524 20%
Emulsifiable Concentrate Fungicide
Acute oral... Inert ingredient info on page 1 not included.
Tox review 002368.

April 11, 1975. Review. 9 Page(s).
J.W. Akerman. Ecological Effects Branch.
Ortho Rose Disease Control. Funginex (Triforine).
Fish, Bird Environmental Safety Data Submitted for Review.

August 19, 1975. Review. 21 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
Reg. No. 239-EUGL. Ortho Rose Disease Control
Registration.

September 4, 1975. Review. 6 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
Reg. No. 21137-8.
Data to clarify previous submitted data.

January 27, 1976. Review. 4 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
EPA File No. 239-EUGL. Ortho Rose Disease Control
Registration for Outdoor Use on Roses, Crapemyrtle, Phlox
and Zinnies.

March 20, 1976. Review. 5 Page(s).
Scott Fredericks. Efficacy & Environmental Effects Branch.
EPA File No. 239-EUGL. Ortho Rose Disease Control
Registration for Use on Roses.

April 6, 1976. Review. 13 Page(s).
Laurence Chitlik. Toxicology Branch.
EPA Reg. # 239-EUGL. Ortho Rose Disease Control.
Registration Human Safety Review.
Inert ingredient information on page 3 not included.
Pages 12-13 removed, draft labeling.
Tox review 002366.

April 27, 1976. Review. 3 Page(s).
Joe Boyd. Efficacy & Environmental Effects Branch.
EPA Reg. No 21137-4. CELA W524 20% Emulsifiable Concentrate
Greenhouse Use on Roses.

September 4, 1976. Review. 5 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
EPA Reg. No. 21137-8. Cela W-524 Emulsifiable Concentrate
Data to Clarify Previous Submitted Data.

February 1, 1977. Review. 4 Page(s).
H.T.Craven. Efficacy & Environmental Effects Branch.
Funginex - E.C. (Triforine). Aerial Application to
Blueberries. Department of Agriculture, Washington State.
Submitted for Special Exemption.

April 7, 1977. Review. 6 Page(s).
Reto Engler. Toxicology Branch.
Tolerances for Triforine. Pesticide Petition # 7F1921.
Tox Review 002367.

August 23, 1977. Review. 19 Page(s).
Robert Hitch. Efficacy & Environmental Effects Branch.
EPA Reg. No. 21137-4. Funginex
Petition: Registration for Amended Use on Peaches
and Blueberries.

October 18, 1977. Review. 2 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
EPA File No. 239-EULL. Ortho Triforine EC.
New Product Registration - Greenhouse Use on Roses.

October 18, 1977. Review. 10 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
EPA Reg. No. 21137-4. 7F1921. Funginex.
New uses on Blueberries and Peaches.

December 12, 1977. Memorandum. 2 Page(s).
Eugene Wilson. Efficacy & Environmental Effects Branch.
EPA Reg. No. 21137-4. Memorandum of Discussion -
Environmental Chemistry Data Submitted in Support of
Registration of Funginex.

January 31, 1978. Review. 9 Page(s).
R.B. Jaeger. Toxicology Branch.
EPA Reg. No. 239-EULL, Ortho Triforine EC.
Acc # 232564. Acute oral LD50...
Tox review 002369.

March 14, 1978. Review. 11 Page(s).
Douglas Urban. Efficacy & Environmental Effects Branch.
EPA File No. 239-EUGL. Ortho Funginex, Triforine.
Registration for Use on Roses
Acc. Nos. 232684, 232695.

June 21, 1978. Review. 17 Page(s).
John Tice. Efficacy & Environmental Effects Branch.
EPA Reg. No. 21137-4. Funginex 20% E.C.
Resubmission with Data
Acc. No 232730.

July 6, 1978. Review. 2 Page(s).
Ronald Ney. Efficacy & Environmental Effects Branch.
EPA Reg. No. 21137-4. 7F1921. Funginex.
Resubmission, Blueberries and Peaches.

July 26, 1978. Review. 3 Page(s).
Gunter Zweig. Environmental Fate Branch.
Reg. No. 21137-402
submission of data - blueberries & peaches.

August 14, 1978. Review. 1 Page(s).
H.W. Spencer. Toxicology Branch.
Explanation of Acute Inhalation Toxicity Study: Label
Change of Practical Treatment of Ortho Triforine E.C.
Tox review 002370.

November 16, 1978. Memorandum. 5 Page(s).
Review Section No. 1. Environmental Fate Branch.
Reg./File No. 239-2455. Ortho Triforine EC
added uses roses outdoor and asters
also change in rate for greenhouse roses.

November 20, 1978. Review. 10 Page(s).
Henry Craven. Ecological Effects Branch.
Reg. No. 21137-4. Funginex
Data Review and Amendment to Add Blueberries and Peaches.

May 30, 1979. Review. 3 Page(s).
Clayton Bushong. Ecological Effects Branch.
EPA Reg. No. 21137-4. Funginex 20% EC (Triforine). E.M.
Laboratories. Resubmission with Data.

August 9, 1979. Review. 5 Page(s).
Review Section No. 1. Environmental Fate Branch.
EPA Reg. No. 21137-4. Funginex EC (Triforine). EM
Laboratories, Inc. Resubmission - Blueberries and Peaches.

August 16, 1979. Memorandum. 1 Page(s).
Clayton Bushong. Ecological Effects Branch.
Incremental Risk Assessment for Ortho Triforine EC
(239-2455).

September 10, 1979. Data Eval. Rec. 7 Pages(s).
Curtis Laird. Ecological Effects Branch.
F.E. Reno. Acute oral LD50 of triforine
technical to bobwhite quail. Hazleton America,
Inc. Page 7 removed, manufacturing process information.
Registration No. 21137-4.

September 17, 1979. Review. 2 Page(s).
Clayton Bushong. Ecological Effects Branch.
EPA Reg. No. 21137-4. Funginex 20% Emulsifiable
Concentrate (Triforine). E.M. Laboratories, Inc. Data
Validation.

September 27, 1979. Review. 9 Page(s).
Krystyna Locke. Toxicology Branch.
Ortho Multipurpose Rose and Flower Spray.
EPA File Symbol: 239-EUAI
Accession No. 238698, 238697. 238729
Inert ingredient information on pages 2-3 not included.
Tox review 002371.

January 30, 1980. Review. 6 Page(s).
Clayton Bushong. Ecological Effects Branch.
EPA File No. 239-EUAI. Ortho Multipurpose Rose & Flower
Spray (Acephate 4.0%, Triforine 3.25%, Dicofol 3.0%
formation). Chevron Chemical Company. Sec 3 for Use on
Roses and Ornamentals.

June 3, 1980. Memorandum. 5 Page(s).
Willa Garner. Environmental Fate Branch.
EPA Reg./File No. 21137-4, 0F2351, 0F2352, 0F2353.
Funginex (Triforine). EM Industries. Request for New Food
Uses.

June 13, 1980. Review. 14 Page(s).
Clayton Bushong. Ecological Effects Branch.
EPA Reg. No. 21137-4. 0F2353.
Incremental Risk - Almonds & Apples.
Inert ingredient information on pages 4-7, 12 not included.

September 9, 1980. Review. 6 Page(s).
Charles Frick. Toxicology Branch.
PP#0F2351, 0F2352, 0F2353 and Registration 21137-4 Triforine
Inert ingredient information on pages 2, 3, 5 not included.
Tox review 003801.

December 5, 1980. Memorandum. 8 Page(s).
John Onley. Residue Chemistry Branch.
PP#0F2353. Triforine in or on Almonds and Apples.
Evaluation of Analytical Methods and Residue Data.
Inert ingredient information on pages 2 and 3 not included.

December 10, 1980. Review. 2 Page(s).
John Onley. Residue Chemistry Branch.
Memorandum of Conference on Triforine.

October 22, 1981. Memorandum. 4 Page(s).
Charles Frick. Toxicology Branch.
Teratogenicity Study in Himalayan Rabbits for Inclusion
into Triforine Data Base
Tox review 001128.

November 5, 1981. Memorandum. 3 Page(s).
Byron Backus. Insecticide-Rodenticide Branch.
EPA Reg. No 239-2468. Ortho Multipurpose Rose & Flower Spray
Acc. 246062. Page 3 removed, draft label.
Tox review 001178.

December 21, 1981. Memorandum. 4 Page(s).
Fish and Wildlife Biologist. Ecological Effects Branch.
Conditional Registration of Funginex (Reg. # 21137-4)
on Almonds. Pages 2-4 removed, draft label.

December 21, 1981. Review. 5 Page(s).
Clayton Bushong. Ecological Effects Branch.
EPA Reg. No. 21137-4. Funginex E.C.
Proposed Conditional Registration of Apple Use.

September 3, 1982. Review. 1 Page(s).
W Teeters. Toxicology Branch.
IBT Validation Report
Mutagenic Study with CELA W-524 Technical in Albino Mice
Tox review 002766.

November 19, 1982. Review. 1 Page(s).
Laurence Chitlik. Toxicology Branch.
IBT Validation Report
14-Day Subacute Vapor Inhalation Toxicity Study
with EC-Cela W-524 (Triforine) in Albino Rats.
Tox review 002767.

March 29, 1983. Review. 6 Page(s).
Clayton Bushong. Ecological Effects Branch.
EPA File No. 279-EUP-OA. Funginex 1.6 EC
FMC Corporation. Proposed EUP for use on Almonds
(California).

March 29, 1983. Review. 2 Page(s).
Emil Regelman. Environmental Fate Branch.
EPA File No. 279-EUP-OA. Funginex 1.6. EM Industries.
Experimental Use Permit on Almonds.

April 5, 1983. Memorandum. 4 Page(s).
Orville Paynter. Toxicology Branch.
83-CA-38 - The California Dept. of Food and Agriculture
Request a Section 18 Exemption to Use the Pesticide Chemical
Triforine on Almonds for the Control of Benomyl Resistant
Brown Rot.
Tox review 003784.

October 11, 1984. Review. 5 Page(s).
Clayton Bushong. Ecological Effects Branch.
EPA Reg. No. 21137-4. Funginex. EM Industries, Inc.
Submission of Data in Response to Previous Review.

October 23, 1984. Profile. 5 Page(s).
Clayton Bushong. Ecological Effects Branch.
Ecological Effects Breanch Chemical Profile.

December 27, 1984. Review. 3 Page(s).
Curtis Laird. Ecological Effects Branch.
EPA File No. 279-EUP-96. Funginex 1.6 EC. FMC Corporation.
Proposed EUP Extension for use on Almonds
Acc. 254990.

January 17, 1985. Review. 5 Page(s).
Samuel Creeger. Exposure Assessment Branch.
EPA File No. 279-EUP-96. Environmental Fate Review of
Funginex 1.6 EC (Triforine). FMC Corporation.
Extension of EUP on Almonds.
Pages 4-5 removed, draft labeling.

February 19, 1985. Memorandum. 5 Page(s).
Stephanie April. Toxicology Branch.
Triforine, Replacement IBT mutagenicity data.
Acc. 253815.
Tox review 004328.

February 6, 1986. Review. 9 Page(s).
Curtis Laird. Ecological Effects Branch.
EPA Reg. No. 21137-4. Funginex 20EC. EM Laboratories, Inc.
Submission of data to support registration of almonds.
Acc. 095811.

September 9, 1986. Memorandum. 14 Page(s).
Whang Phang. Toxicology Branch.
Review of Four Mutagenicity Studies on triforine.
Accession No. 260032
Tox review 005449.

September 9, 1987. Review. 3 Page(s).
Emil Regelman. Exposure Assessment Branch.
EPA Reg. No. 21137-4. Funginex. EM Industries, Inc.
Label Changes - Additional Uses.

November 16, 1990. Memorandum. 9 Page(s).
Sheila Moats. Toxicology Branch.
EPA Reg. No. 21137-4. Funginex Emulsifiable Concentrate.
MRID 415710-03 thru 08. Acute oral, dermal, inhalation...
Inert ingredient information on page 2 is not included.
Tox review 008660.

July 6, 1992. Memorandum. 18 Page(s).
Dan Hanke. Toxicology Branch II.
Triforine Technical Data Review.
MRID 421727-01, 02, 03. Acute oral, dermal, inhalation.
Tox review 009581.

July 29, 1993. Memorandum. 23 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Review of a mouse carcinogenicity study.
Pages 14-23 removed, registration data.
MRID 424540-01
Tox review 010438.

September 15, 1993. Memorandum. 24 Page(s).
Alberto Protzel. Toxicology Branch.
Triforine: Acute toxicity and chronic feeding (dog)
toxicity data review.
Page 11 removed, registration data.
MRID 423804-07 thru -10
Tox review 010573.

November 2, 1993. Memorandum. 54 Page(s).
David Liem. Toxicology Branch.
Review of a Chronic Toxicity/Oncogenicity study with
Triforine Technical.
Pages 20-53 removed, registration data.
MRID 4241120-01 thru -05
Tox review 010643.

December 3, 1993. Memorandum. 27 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Evaluation of developmental toxicity studies
in rats and rabbits.
MRID 428892-01 (rat); 428892-02 (rabbit)
Tox review 010687.

December 8, 1993. Memorandum. 1 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Comments on the possibility of upgrading a
chronic feeding study in dogs.

February 10, 1994. Memorandum. 2 Page(s).
Alberto Protzel. Toxicology Branch.
Triforine. Two-Generation reproductive toxicity data
review.
MRID 423718-01
Tox review 019779.

June 7, 1994. Memorandum. 9 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Review of a gene mutation assay in Chinese
hamster ovary cells.
MRID 43082401
Tox review 011034.

January 19, 1995. Memorandum. 1 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Evaluation of supplemental data of a
developmental toxicity studies in rats.
MRID 432221-01
Tox review 011390.

January 25, 1995. Memorandum. 17 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Evaluation of supplemental data for a
chronic feeding toxicity study in dogs.
MRID 432221-02
Tox review 011393.

January 31, 1995. Memorandum. 27 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Evaluation of supplemental data of a
2-generation reproduction study in rats.
Pages 4-8 removed, registration data.
MRID 433233-01
Tox review 011400.

January 8, 1998. Memorandum. 21 Page(s).
Whang Phang. Toxicology Branch.
Triforine: Evaluation of two developmental toxicity
studies in rabbits.
MRID 43664901 & 43664902
tox review 012445.

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