Stevens, F.J. and T.T. Wu. 1974. A third stage mutant of E. coli capable of utilizing
he polyhydric pentitols as sole source of carbon and energy. Abstr. Ann. Mtg. Am.
Soc. Microbiol., p 156.
Stevens, F.J. and T.T. Wu. 1976. Acquisition by E. coli K 12 of the ability to utilize
an unnatural pentose, D lyxose. Federation Proc. 35: 1660.
Stevens, F.J. and R.L. Uffen. 1977. Acquisition of photosynthetic competence by
anaerobic dark grown cells of R. rubrum exposed to light. Presented at 4th Ann. Mtg. on the
Molec. Biol. of Photosyn. Microorganisms; May 7.
Stevens, F.J., H.S. Pankratz, and R.L. Uffen. 1977. Cytochemical and spectrophotometric
examination of the effect of glutaraldehyde on the oxidation of 3,3' diaminobenzidine in
phototropic bacteria. Cell Biology 75: 244a.
Stevens, F.J., F. Westholm, A. Solomon, and M. Schiffer. 1979. Heterogeneity of κI light chains. Federation Proc. 38: 940.
Stevens, F.J., F.A. Westholm, A. Solomon, and M. Schiffer. 1979. Role of the third
hypervariable region in the self association of κI immunoglobulin light chains.
Presented at Midwest Autumn Immunology Conference; November 5.
Stevens, F.J., F.A. Westholm, A. Solomon, and M. Schiffer. 1980. Computer simulation
of small zone gel filtration: heterologous association of immunoglobulin light chains.
Federation Proc. 39: 2210.
Schiffer, M., F.J. Stevens, F. Westholm, D. Carlson, and B. Schoenborn. 1980. Small angle
neutron scattering study of Bence Jones protein Mcg: comparison of structures in solution
and in crystal. Presented at Gordon Conference on Diffraction Methods in Molecular Biology;
June 21.
Peraino, C., and F.J. Stevens. 1980. Characteristics of liver tumor promotion by
phenobarbital. Presented at Symposium on Cocarcinogenesis and Biological Effects of
Tumor Promoters; Oct. 13 (Klais, West Germany).
Schiffer, M., F.J. Stevens, and F.A. Westholm. 1980. Structural properties of Bence Jones
proteins in the crystal and in solution. 38th Annual Pittsburgh Diffraction Conference; Oct. 30.
Wu, T.T., P.W. Stevens, J.G. Hovis, and F.J. Stevens. 1981. Production of an evolutionary
remnant enzyme in Escherichia coli K 12. FEMS Symposium on Overproduction of Microbiol
Products. Abstracts, p. 43.
Short, M., F.J. Stevens, F. Westholm, A. Solomon, and M. Schiffer. 1980. Preliminary X ray
crystallographic studies of Bence Jones protein Loc. Presented at Midwest Autumn Immunology
Conference; Oct. 18.
Short, M., F.J. Stevens, F. Westholm, A. Solomon, and M. Schiffer. 1982. Crystallographic
investigation of lambda Bence Jones protein Loc. Federation Proc. 41: 287.
Short, M.T., F.J. Stevens, and M. Schiffer. 1983. High pressure gel permeation chromatography
in the study of self associating immunoglobulin I light chains and an idiotype anti idiotype
complex. Federation Proc. 42: 931.
Stevens, F.J., S. Anaokar, G. Korom, J. Tice, and P. Spillar. 1983. Solid phase enzyme
immunoassay for serum leutenizing hormone. Clin. Chem. 29: 1241.
Schiffer, M., R.L. McMasters, C. H. Chang, and F.J. Stevens. 1984. Interactions of
immunoglobulin constant domains. Gordon Research Conference on Physics and Physical
Chemistry of Biopolymers; June 27.
Stevens, F.J. and C.F. Ainsworth. 1985. Antibody antigen interactions: application of
chromatography simulation and laboratory microcomputer. Federation Proc. 44: 1077.
Stevens, F.J. 1985. Application of microcomputer controlled size exclusion chroatography and
computer simulation to analysis of macromolecular interactions. Presented at Amoco sponsored
University/Industry Poster Session; Oct. 23 (Naperville, IL).
Schiffer, M., C. H. Chang, F.J. Stevens, and A. Solomon. 1985. Implications of the protruding
binding site of light chain dimer Loc for the structure of the anti idiotypic antibody. Presented at
Symposium Idiotype Networks and Immune Regulation: Potential Uses in Vaccines and In
Understanding Human Diseases; December 4 (San Antonio).
Stevens, F.J. and M. Schiffer. 1985. Analysis of idiotype:anti idiotype interactions by small zone
size exclusion chromatography: consideration of equilibrium constant and rate constants.
Presented at Symposium Idiotype Networks and Immune Regulation: Potential Uses in Vaccines
and In Understanding Human Diseases; December 4 (San Antonio).
Stevens, F.J. and C.F. Ainsworth. 1986. Microcomputer controlled size exclusion
chromatography. Biophys. J. 49: 88a.
Carperos, W., J. Jwo, and F.J. Stevens. 1986. Analysis of monoclonal antibodies by liquid
chromatography. Presented at Abbott Laboratories, State of Illinois Sponsored Poster Session;
November 26 (North Chicago, IL).
Boernke, W.E. and F.J. Stevens. 1987. HPLC based size exclusion chromatography for the
detection of interactions between nucleic acids and proteins. Biophys. J. 51: 442a.
Stevens, F.J. and M. Schiffer. 1987. Modification of an ELISA based method to determine
affinity: correction for nonlinear relationship between occupancy of antibody binding sites and
attachment of IgG to immobilized antigen. Federation Proc. 46: 491.
Stevens, F.J. 1987. Simulation of macromolecular interactions: kinetically controlled
elution characteristics during size exclusion high performance liquid chromatography. Presented at Amoco sponsored University Industry Poster Session; Oct 8 (Naperville, IL).
Carperos, W.E. and F.J. Stevens. 1987. Application of size exclusion high performance liquid
chromatography for the measurement of antibody antigen dissociation rate constants. Presented
at Amoco sponsored University Industry Poster Session; Oct 8 (Naperville, IL).
Stevens, F.J. 1987. Macromolecular interactions: kinetically controlled elution characteristics
during size exclusion HPLC. Presented at Conference on Biotechnology Research Directions:
Biomolecules; Nov 6 (Argonne, IL)
Carperos, W.E. and F.J. Stevens. 1987. Application of size exclusion high performance liquid
chromatography for the measurement of antibody antigen dissociation rate constants. Presented
at Conference on Biotechnology Research Directions: Biomolecules; Nov 6 (Argonne, IL)
Schiffer, M., C. H. Chang and F.J. Stevens. 1987. Domain domain interactions affect the
expression of idiotope. Presented at Symposium on Idiotype Networks and Immune Regulation:
II Autoimmunity, Cancer, Receptors and Vaccines; Nov 18 (San Antonio).
Stevens, F.J. 1988. Simulation of kinetically controlled elution characteristics exhibited
by macromolecular interactions during size exclusion HPLC. Biophys. J. 53: 400a.
Stevens, F.J., and P. Kaumaya. 1988. Size exclusion HPLC analyses of protein and peptide
epitopes. Presented at Second Conference on Biotechnology Research Directions: Biomolecules;
Nov 4 (Argonne, IL)
Schiffer, M., C. H. Chang, Z.B. Xu and F.J. Stevens. 1989. Modification of antibody binding
site through altered V V domain interactions. J. Cell. Biol. 13A:94.
Boernke, W.E. and F.J. Stevens. 1989. Study of interactions between myeloperoxidase and
nucleic acids by size exclusion HPLC. Biophys. J. 55: 525a.
Stevens, F.J., and P. Kaumaya. 1989. Size exclusion HPLC analyses of peptide epitopes.
FASEB J. 3: A1135.
Schiffer, M., C. H. Chang, Z B. Xu and F.J. Stevens. 1989. Conformational effects and diversity
of antibodies. Presented at 7th International Congress of Immunology, (Berlin).
Spangler, B.D., F.J. Stevens, and E.M. Westbrook. 1989. Binding of monoclonal antibodies to
cholera toxin: comparison of solid phase and solution phase techniques. Presented at
Amoco sponsored University Industry Poster Session; Oct 12 (Naperville, IL).
Stevens, F.J. 1990. Simulation of macromolecular interactions during size exclusion
chromatography: positive cooperativity contribution by gel matrix. Biophys. J. 57: 82a.
Stevens, F.J. 1990. Chromatographic analyses of protein:protein interactions: from the
supercomputer to the kidney. Presented at the University of Illinois at Chicago, Dept. of
Biochemistry; April 19.
Stevens, F.J. 1990. Chromatographic analyses of macromolecular interactions: from the
supercomputer to the kidney. Presented at the Wayne State University, Dept. of Biochemistry;
Sept 4.
Stevens, F.J. 1990. Biophysical aspects of myeloma pathology. University of
Tennessee Knoxville,
School of Medicine; Sept 7.
Myatt, E.A. and F.J. Stevens. 1991. Induction of protein aggregation in nephromimitic solutions.
Biophys. J. 59: 119a.
Shen, B., F.J. Stevens, and U. Luthi. 1991. Elasticity of human erythrocyte spectrin inferred from
conformational analysis. FASEB J. 5: A685.
Myatt, E.A. and F.J. Stevens. 1991. Induction of protein aggregation in nephromimitic solutions. Presented at Gordon Research Conference; June 17 21.
Spangler, B.D., G.D. Armstrong, and F.J. Stevens. 1991. HPLC analysis of pertussis binding to
glycoproteins. Presented at fifteh European Workshop on Bacterial Protein Toxins, Veldhoven, July.
Chen, S., S. Goldin, F.J. Stevens, and B.W. Shen. 1991. Elasticity of human erythrocyte spectrin
inferred from electron microscopic and conformational analysis. Presented at Gordon Research
Conference, Plymouth State College, New London, N.H.; August 5 9.
Stevens, F.J. 1991. Polymerization of immunoglobulin domains: a model system for the development of facilitated macromolecular assembly. (Presented at the Second Foresight Conference on Molecular Nanotechnology, Palo Alto, CA; (November 7 9)).
Stevens, F.J. 1991. Biophysical and computational aspects of immunoglobulin light chain
pathology. Chicago Medical School, North Chicago, IL. Dept of Biochemistry; November 21.
Stevens, F.J., E.A. Myatt, A. Solomon, and M. Schiffer. 1992. Amyloidosis AL: Molecular
model for a biophysical disease. Biophys. J. 61: A211
Stevens, F.J. and R.L. Stevens. 1992. Protein protein interaction kinetics. Presented at
Concurrent Supercomputing Consortium Workshop, CalTech, February 11.
Harrison, H.H., T. Godsey, K. Bedford, A. Katta, K. Miller, E. Weisenberg, J.E. Bowman, E.Myatt, C.S. Giometti, and F.J. Stevens. 1992. Comparison of microheterogeneity
patterns of purified monoclonal light chains (Bence Jones proteins) and polyclonal free light chains that produce the pseudo oligoclonal (“ladder light chain”') pattern in immunofixation studies of urine. Clin. Chem.
Stevens, F.J. 1992. Analysis of antibody light chain interactions: modeling of amyloid fibril
formation. Presented at Northern Illinois University, De Kalb, IL, Oct. 2.
Gaasterland, T., R.L. Stevens, F.J. Stevens, and M. Schiffer. Critiquing protein molecule
structures. Presented at The Third Keck Symposium on Computational Biology, Houston, TX,
Nov. 1 3, 1992.
Myatt, E.A., A. Solomon, and F.J. Stevens. Aggregation of immunoglobulin light chains.
J. Immunol. 150: 861, 1993.
Li, D., F.J. Stevens, M. Schiffer, and L.E. Anderson. Cysteine clusters in the light activated
chloroplast enzymes. Plant Physiol. 102: 37, 1993.
Li, D., F.J. Stevens, M. Schiffer, and L.E. Anderson. Identification of redox sensitive cysteines
distal to catalytic site in light activated chloroplastic glyceraldehyde 3 phosphate dehydrogenase
by modeling. Presented at The XIII Midwest Enzyme Conference, Loyola University, Oct 9, 1993.
Huang, D. B., C. H. Chang, C. Ainsworth, M. Schiffer, F.J. Stevens, A. Brunger, M. Eulitz, and
A. Solomon. Novel immunoglobulin variable domain interaction is observed. ACA Meeting,
Albuquerque, PK14, 1993.
Jiang, X., P. Lykos, M. Schiffer, and F.J. Stevens. The design and evaluation of the peptide
inhibition of antibody light chain dimer formation by molecular modeling. Presented at The
Second Annual Development of Small Molecule Mimetic Drugs, Philadelphia, April 11 12, 1994.
Stevens, F.J. A molecular model for amyloid fibril formation by antibody light chains.
Presented at Loyola University, Chicago, April 21, 1994.
Li, D., F.J. Stevens, M. Schiffer, and L.E. Anderson. Mechansims of light modulation:
identification of potential redox sensitive cysteines in chloroplast fructose 1,6 bisphosphatase
and sedoheptulose 1,7 bisphosphatase. FASEB J. 8: A1290, 1994.
Muslin, E.H., D. Li, M. Schiffer, F.J. Stevens, M.I. Donnelly, and L. Anderson. Construction of a
redox sensitive malate dehydrogease. Presented at XIV Annual Midwest Autumn Enzymology
Conference. 1994
Stevens, F.J. Physcial chemical aspects of antibody interactions with itself, antigen, and solid
surfaces. Presented at Surfaces in Biomaterials '94, Scottsdale, AZ., Sept 8 10, 1994.
Li, D., E. H. Muslin, L.E. Anderson, M.M. Pacold, M. Donnelly, M. Schiffer, and F.J. Stevens.
Engineering a domain-locking disulfide into a bacterial malate dehydrogenase produces a redox-
sensitive enzyme. FASEB J. 9:A1284, 1995.
Paul, S., L. Li, P. Wilkins-Stevens, F.J. Stevens, and A.Solomon. Natural catalytic antibodies:
peptide hydrolyzing activities of monoclonal human light chains and VL fragment. FASEB J 9:
1265, 1995.
Kalaga, R., H. Huang, F.J. Stevens, A. Solomon, and S. Paul. gp120 hydrolysis by catalytic
antibody light chain. Presented at The 9th International Congress of Immunology, San Fransisco,
CA, July 23-29, 1995.
65. Jiang, X.-L., E.A. Myatt, R. Raffen, and F.J. Stevens. Study of interactions between amyloid
forming protein and glycosaminoglycans. Presented at Protein Interactions. Pfizer/Beckman
Institute Protein Symposium. Urbana, IL, June 1-4, 1995.
66. Anderson, L.E., H.C. Huppe, D. Li, and F.J. Stevens. Identification of a potential recdox
-sensitive inter-domain disulfide in the sedoheptulose bisphosphatase of Chlamydomonas
reinhardtii. Presented at Xth International Photosynthesis Congress, Montpellier, France,
August 20-25, 1995.
Stevens, F.J. Molecular studies of light chain amyloidosis. Presented at FASEB Conference:
Amyloid and other Abnormal Protein Assembly Processes, Copper Mountain, CO, August 20-
25, 1995.
Mulsin, E.H., F.J. Stevens, and L.E. Anderson. A disulfide bridge stabilizes anaerobically
induced lactate dehydrogenase in barley. Presented at Thoiredoxins and Related Proteins,
Witzenhausen, University of Kassel, August 27-31, 1995.
Anderson, L.E., D. Li, E.H. Muslin, M.E. Pacold, M.I. Donnelly, M. Schiffer, and F.J. Stevens.
Mechanism of light modulation: Identification of redox-sensitive cysteines in malate
dehydrogenase by modeling and by site-directed mutagenesis. Presented at Thioredoxins and
Related Proteins, Witzenhausen, University of Kassel, August 27-31, 1995.
Muslin, E.H., F.J. Stevens, and L.E. Anderson. Anaerobically induced lactate dehydrogenase:
The role ofa disulfide bridge in enzyme stability. Presented at XV Annual Midwest Autumn
Enzymology Conference. Chicago, IL. Oct 15, 1995
Li, A.D., H.C. Huppe, F.J. Stevens, and L.E. Anderson. Chlamydomonas reinhardtii NADP-
linked glyceraldehyde-3-phosphate dehydrogenase is DTT-activatable. Presented at XV Annual
Midwest Autumn Enzymology Conference. Chicago, IL. Oct 15, 1995
Anderson L.E., A. D. Li, E.H. Muslin, M.E. Pacold, M.I.Donnelly, M. Schiffer, and F.J. Stevens
1995. Mechansim of light modulation: identification of redox-sensitive cysteines in target
enzymes by modeling and by site-directed mutagenesis. Presented at XV Annual Midwest
Autumn Enzymology Conference. Chicago, IL. Oct 15.
Muslin E.H., A. D. Li, F.J. Stevens, M. Schiffer, M. Donnelly, and L.E. Anderson. 1995. The
engineering of new domain-locking disulfides into a bacterial malate dehydrogenase strengthens
evidence for original model of reductive activation of the chloroplast enzyme. Presented at
Photosynthesis Symposium, Turkey Run, IN, Oct.
Raffen, R., P. Wilkins Stevens, D.K. Hanson, Y. Deng, M. Berrios-Hammond, F.A. Westholm,
M. Schiffer, and F.J. Stevens. 1996. In vitro characterization of light chain amyloidosis using
recombinant light chain variable domains. Biophysical J.
Levine, D. and F.J. Stevens. 1996. STALK: A Molecular Docking System. Presented at
The Second Sandia National Laboratories Workshop on Computational Molecular Biology,
March 4 6, 1996, Albuquerque, New Mexico
Huang, D.-B., C. Ainsworth, C.-H. Chang, F.J. Stevens, and M. Schiffer. 1996. Structure of the
variable domain of human immunoglobulin IV light chain Len Presented at the International
Union of Crystallography XVII Congress and General Assembly, Seattle, WA., Aug 8-17.
Stevens, F.J. 1996. Biophysical pathology of human antibody light chains. Presented at NYU
Medical School, New York, Nov 26.
Khurana, R., F.J. Stevens, S. Meredith, and Y. Argon. 1997. Interaction of BiP with partially
unfolded variable domain of immunoglobulin light chain. Presented at Keystone Conference,
March.
Schiffer, M., D.-B. Huang, R. Raffen, R. Pokkuluri, P. Wilkins-Stevens, and F.J. Stevens. 1997.
Major unexpected effect of a Gln to Glu substitution on a dimer interface. 1997 Proteins Gordon
Conference.
Raffen, R., L.J. Dieckman, P. Wilkins Stevens, P.R. Pokkuluri, M. Schiffer, and F.J. Stevens.
1997. Characterizing primary structural determinants of immunoglobulin light chain amyloidosis
with recombinant light chain variable domains. FASEB Summer Research Conference on
"Amyloid and other Abnormal Protein Assembly, July 13-18, Copper Mt. CO.
Pokkuluri, P.R., D.-B. Huang, R. Raffen, P. Wilkins-Stevens, F.J. Stevens, and M. Schiffer.
1997. How do metal ions help (promote) the formation of protein crystals? The Annual
American Crystallographic Association Meeting, July 19-25, St. Louis, MO.
Stevens, F.J. 1997. Conformational diseases of immunoglobulins. Presented at University
of Chicago, Dept of Pathology, Oct 13.
Stevens, F.J. 1997. Amino acid sequences, protein bioophysics and the pathological expression
of light chains. Presented at the 30th Annual Meeting of the American Society of Nephrology,
San Antonio, Nov 2-5.
Deret, S., J. Chomilier, F. Stevens, and P Aucouturier. 1997. Particularites structurales des chaines
legeres d’immunoglobulines responables de la maladie des depots de chaines legeres (LCDD).
Presented at the 10 Annual Meeting of the GGMM (Groupe du Graphisme et Modelisation
Moleculaire), Dourdan, France.
Stevens, F.J. 1998. Conformational diseases of antibody light chains. Presented at University of
Illinois, Chicago, Feb 12.
Pokkuluri, P.R., G. Johnson, X. Cai, L. Dieckman, F.J. Stevens, and M. Schiffer. 1998.
Domain flips resulting from single amino acid substitutions. American Crystallographic
Association Meeting.
Schiffer, M., P.R. Pokkuluri, X. Cai, G. Johnson, R. Raffen, and F.J. Stevens. 1998. A single
amino acid substitutions changes the mode of dimerization. Presented at The Thrid Annual
Structural Biology Symposium, University of Texas Medical Branch at Galveston, April 3-5.
Dogar, J. and F.J. Stevens. 1998. Use of computerized homology modeling and threading
techniques to predict immunodominant epitopes of Fel d 1 on MHC Class-II molecules.
Presented at Aspen Allergy Conference, July 29 - Aug1.
Raffen, R., P.R. Pokkuluri, P. Wilkins Stevens, M. Schiffer, and F.J. Stevens. 1998.
Characterization of immunoglobulin light chain amyloidosis by site-directed mutagenses.
Presented at Protein Society Symposium, San Diego, CA., July 25-29.
Stevens, F.J. 1998. Applications of protein engineering: From a killer protein to detection of
actinides. Presented at Northwestern University, Dept. of Biomedical Engineering, Dec 3.
Stevens, F.J., R. Raffen, L. J. Dieckman, M. Szpunar, P.R. Pokkuluri, P.W. Stevens, and M. Schiffer. 1999. Characterization of immunoglobulin light chain pathoenic aggregation and amyloidosis by site-directed mutagenesis. Presented at 4th Annual Midwest Stress
Response and Chaperone Meeting., Jan 16.
Davis, D.P., S. Vogen, C. Case, R. Raffen, F. Stevens, and Y. Argon. 1999. Unlocking the
mechanisms of immunoglobulin aggregation disorders. Presented at 4th Annual Midwest Stress
Response and Chaperone Meeting, Jan 16.
Schiffer, M., P.R. Pokkulur, R. Raffen, X. Cai, G. Johnson, and F.J. Stevens. 1999. Alteration of
dimerization mode by single amino substitutions. Presented at 13th Symposium of the Protein
Society, Boston, MA, July 24-28.
Li, A.D., L.E. Anderson, M. Schiffer, and F.J. Stevens. 1999. Identifying potential disulfides by
homology modeling. Presented at XVIth International Botanical Congress, St. Louis, Aug 1-7.
Anderson, L.E., A.D. Li, and F.J. Stevens. 1999. Identification of potential redox-sensitive
cysteine residues in the reductase domains of two plant dihydrofolate reductase-thymidylate
synthases. Presented at XVIth International Botanical Congress, St. Louis, Aug 1-7.
Anderson, L.E., A.D. Li, and F.J. Stevens. 1999. Finding redox-regulated enzymes by homology
modeling. Presented at Russian Society for Plant Physiology meeting, Moscow, Oct.
Dong, A., Y.-S. Kim, R. Raffen, T.W. Randolph, A. Solomon, P. Wilkins Stevens, F.J. Stevens,
and J.F. Carpenter. 2000. Entrapping aggregation intermediates of α-helix and β-domain proteins
by thermochemical denaturation: an infrared spectroscopic study. Presented at FASEB
Conference: Amyloid and other Abnormal Protein Assembly Processes, Copper Mountain, CO,
June 11-16.
Kim, Y.-S., S.P., E. Chi, R. Raffen, P.Wilkins Stevens, F.J. Stevens, A. Solomon, M.C.
Manning, T.W. and J.F. Carpenter. 2000. Counteracting effects of renal solutes on amyloid fibril
formation by immunoglobulin light chains. Presented at FASEB Conference: Amyloid and other
Abnormal Protein Assembly Processes, Copper Mountain, CO, June 11-16.
Stevens, F.J. and S. Filer. 2000. Novel strategy using synthetic nucleic acids and conventional
immunoassays for biological agent detection. Third International Symposium; Chemical and
Biological Medical Treatment Symposia (CBMTS). AC-Laboratorium, Spiez, Switzerland,
May 7-12.
Manning, M.C., R. Meglan, and F.J. Stevens. 2000. Decoding the sequences of antibody light
chains: the power of multivariate statistical analysis. Presented at the 2000 Colorado Protein
Stability Conference, Breckenridge, Colorado, July 13-15.
Davis, D.P., K. Sciarretta, S.M. Vogen, J. L. Dul, F.J. Stevens, and Y. Argon. 2001. Both somatic
mutation and environmental factors govern the aggregation pathway. Canadian Society of
Biochemistry and Molecular & Cellular Biology. 11th Winternational Conference: “Dynamics of
Intracellular Organelles and Molecular Machines.” Mont Ste. Anne, Feb 8-11.
Dul, J.L., D.P. Davis, E.K. Williamson, F.J. Stevens, and Y. Argon. 2001. Hsp70 and anti-
fibrillogenic peptides promote degradation and inhibit intracellular aggregation of amyloidogenic
light chains. Canadian Society of Biochemistry and Molecular & Cellular Biology.
11th International Conference: “Dynamics of Intracellular Organelles and Molecular
Machines.” Mont Ste. Anne, Feb 8-11.
Stevens, F.J. 2001. Protein structure, biophysics, and disease. Presented at Northern Illinois
University, April 20.
Wan, K., M. Duan, Y.-M. Lin, Y.-M., J. Lin, R. Raffen, and F.J. Stevens. 2001. The study of
protein-protein interactions by H/D exchange and ESI MS. Presented at 49th Annual Conference
on Mass Spectrometry and Allied Topics, Chicago, IL, May 27-May31.
Stevens, F.J. 2001. Protein structure, biophysics, and disease. Presented at MediChem Research,
Inc. Woodridge, IL, June 5.
Silver, R.B., J.R. Hummel, J.H. Christiansen, S.R. Filer, and F.J. Stevens. 2001. A multi-modal biosensor and decision system. Presented at 5th Joint Conference on Standoff and Detection, Williamsburg, VA, Sept 24-27, 2001.
Stevens, F.J. 2002. The challenge of the megaproteins: Speculations on the structures of BRCA1 and BRCA2. Presented at the University of Illinois at Chicago, Bioengineering Dept, Sept 20.
Stevens, F.J. 2003. BRCA1 and BRCA2: Structure predictions without significant homology: soluble domains, functional validation. Presented at the University of Chicago, Feb 14.
Stevens, F.J. 2003. New directions for analysis of megaproteins and other inhabitants of the twilight and midnight zones. Presented at Advanced Life Sciences, Woodridge, Il, June 13.
Stevens, F.J. 2003. Structural relevance of germline gene to light chain amyloidosis. Presented at Mayo Clinic, Rochester, MN, Sept 24.
Stevens, F.J. 2003. Structural insights from sequence analysis. Presented at Children’s Hospital of Philadelphia, Oct 1.
Stevens, F.J. 2003. Protein self-assembly: a normal process, a pathological process, a nanotechnical process. Presented at Argonne National Laboratory, Nanolunch seminar series, Oct 15.
Stevens, F.J. 2003. Recognition of protein fold (and sometimes function) from sequence at very low levels of identity. Presented at Bioinformatics Workshop, Ft. Detrick, Md. Nov 5.
Wilton, R, P. Saxena, and F.J. Stevens. Expression, purification, and biochemical characterization of the human receptor for advanced glycation endproducts (RAGE). Presented 18th Symposium of the Protein Society, San Diego, Aug 14-18, 2004.
PUBLICATIONS (book chapters):
Stevens, F.J. and C. Peraino. 1982. Development of a model to simulate the characteristics of
rat liver tumor promotion by phenobarbital. In Proceedings of the Symposium on
Cocarcinogenesis and Biological Effects of Tumor Promoters, eds. E. Hecker, N.E. Fusenig, W.
Kunz, F. Marks, and H.W. Thielmann, pp. 105 109, Raven Press, New York.
Wu, T.T., P.W. Stevens, J.G. Hovis, and F.J. Stevens. 1982. Production of an evolutionary
remnant enzyme in Esherichia coli K 12. In Overproduction of Microbiol Products, eds.
V. Krumphanzl, B. Sikyta, Z. Vanek, pp. 417 423. Academic Press, London.
Peraino, C., W.L. Richards, and F.J. Stevens. 1983. Multistage hepatocarcinogenesis. In
Mechanisms of Tumor Promotion, Vol.I, Tumor Promotion in Internal Organs, ed. T.J. Slaga,
pp. 1 53. CRC Press.
Stevens, F.J. and C. Peraino. 1983. Liver as a model system for analyzing mechanisms of tumor
initiation and promotion. In Organ and Species Specificity in Chemical Carcinogenesis, eds.
R. Langenbach, S. Nesnow and J.M. Rice, Plenum Press, pp. 231 252.
Stevens, F.J. 1989. Size exclusion high performance liquid chromatography in analysis
of protein and peptide epitopes. Methods in Enzymology 178: 107 130.
Stevens, F.J. 1991. Considerations of the interpretation of the specificity of monoclonal antibodies
determined in solid phase immunoassays. In The Immunochemistry of Solid Phase
Immunoassays, pp 233 242, ed. J.E. Butler, CRC Press, New York.
Spangler, B.D., G.D. Armstrong, and F.J. Stevens. 1992. HPLC analysis of pertussis toxin
binding to glycoproteins, in Bacterial Protein Toxins (5), pp 300 301,
Witholt et al., eds., Gustav Fischer Verlag, Stuttgart.
Stevens, F.J. and M. Schiffer. 1995. Structure and properties of human immunoglobulin
light chain dimers, in Methods in Molecular Biology, Vol 51: Antibody Engineering Protocols,
ed. S. Paul., pp 51-81. Humana Press Inc, Totowa, NJ.
Schiffer, M. and F.J. Stevens. 1995. Crystallographic and chromatographic methods for study of
antibody light chains and other proteins, in Methods in Molecular Biology, Vol 51: Antibody
Engineering Protocols, ed. S. Paul., pp 83-98. Humana Press Inc, Totowa, NJ.
Anderson, L.E., H.C. Huppe, A.D. Li, and F.J. Stevens. 1996. The sedoheptulose bisphosphatase
of Chlamydomonas reinhardtii contains a potential inter-domain disulfide and is redox-sensitive.
Proceedings of Xth International Photosynthesis Congress, Montpellier, France. In
Photosynthesis from Light to Biosphere, Vol. V, pp 71-74. Ed, P. Mathis.
Stevens, F.J., D.T. Weiss, and A. Solomon. 1998. Structural bases of light chain-related pathology. In The Antibodies, Vol 5, pp 175-208. M. Zanetti and J.D. Capra, eds. Harwood Academic Publishers, Australia
Raffen, R. and Stevens, F.J. 1999. Small-zone, high-speed gel filtration chromatography to detect
protein aggregation associated with light chain pathologies. Meth. Enzymol. 309: 318-332.
Stevens, F.J., M. Schiffer, and Y. Argon. 2002. Thermodynamic aspects of immunoglobulin
light chain disease. In Conformational Diseases – A Compendium. Based on the First International Workshop on Conformational Diseases, pp 135-150, ed B. Solomon, A. Taraboulos, and E. Katchalski-Katzir. The Center for the Study of Emerging Diseases.
Wilton, R., E.A. Myatt, and F.J. Stevens. 2003. SCIMMS: Simulated chromatography of interactive
macromolecular systems. In Protein-Protein Interactions: Methods and Protocols, ed. H. Fu, Humana Press, Totowa, NJ.
Kay, B.K., M. Scholle, and F.J. Stevens 2004. EH domains and their ligands. (in press)
Stevens, F.J. 2004. Amyloid proteins. Immunoglobulin (AL, AH). In Amyloid Proteins:
The Beta Pleated Sheet Conformation and Disease, ed J. Sipe, Wiley.
PUBLICATIONS (peer reviewed):
Stevens, F.J. and T.T. Wu. 1976. Growth on D lyxose of a mutant strain of Escherichia coli
K 12 using a novel isomerase and enzymes related to D xylose metabolism. J. Gen. Microbiol.
97: 257 265.
Stevens, F.J., H.S. Pankratz, and R.L. Uffen. 1977. Demonstration of two 3,3' diaminobenzidine
reactions associated with photosynthetic membranes in anaerobic, light grown Rhodospirillum
rubrum. J. Histochem. Cytochem. 25: 1264 1268.
Stevens, F.J., F. Westholm, A. Solomon, and M. Schiffer. 1980. Self association of human
immunoglobulin I light chains: role of the third hypervariable region. Proc. Natl. Acad. Sci
USA 77: 1144 1148.
Peraino, C., E. Staffeldt, D.A. Haugen, L.S. Lombard, F.J. Stevens, and R.J.M. Fry. 1980. Effects
of varying the dietary concentration of phenobarbital on its enhancement of
2 acetylaminofluorene induced hepatic tumorigenesis. Cancer Res. 40: 3268 3273.
Boernke, W.E., F.J. Stevens, and C. Peraino. 1981. Effects of self association of
ornithine aminotransferase on its physico chemical characteristics. Biochemistry 20: 115 121.
Stevens, F.J., P.W. Stevens, J.G. Hovis, and T.T. Wu. 1981. Some properties of
D mannose isomerase from Escherichia coli K 12. J. Gen. Microbiol. 124: 219 223.
Stevens, F.J., F.A. Westholm, N. Panagiotopoulos, A. Solomon, and M. Schiffer. 1981.
Preliminary crystallographic data on the human λ III Bence Jones dimer Cle.
J. Molec. Biol. 147: 179 183.
Stevens, F.J., F.A. Westholm, N. Panagiotopoulos, M. Schiffer, R.A. Popp, and A. Solomon.
1981. Characterization and preliminary crystallographic data from the VL related fragment of the
human I Bence Jones protein Wat. J. Molec. Biol. 147: 185 193.
Stevens, F.J. and M. Schiffer. 1981. Computer simulation of protein self association during
small zone gel filtration: estimation of equilibrium constants. Biochem. J. 195: 213 219.
Schiffer, M., F.J. Stevens, F.A. Westholm, D. Carlson, and B. Schoenborn. 1982. Small
angle neutron scattering study of Bence Jones protein Mcg: comparison of structures in solution and in crystal. Biochemistry 21: 2874 2878.
Gierczak, J.S., F.J. Stevens, H.S. Pankratz, and R.L. Uffen. 1982. Cytochemical localization
and measurement of aerobic 3,3' diaminobenzidine oxidation reactions in photosynthetically grown Rhodospirillum rubrum . J. Histochem. Cytochem. 30: 901 907.
Boernke, W.E., F.J. Stevens, J.E. Edwards, and C. Peraino. 1982. Differential changes in
ornithine aminotransferase self affinity produced by exposure to basic amino acids and increases
in the intrinsic electronegativity of the enzyme monomer. Arch. Biochem. Biophys. 216:
152 157.
Short, M.T., W.J. Eisler, and F.J. Stevens. 1983. Automated failsafe control system for
independent operation of two radiation shutters on a rotating anode X ray source. J. Appl.
Crystal. 16: 359 360.
Short, M.T., F.A. Westholm, M. Schiffer, and F.J. Stevens. 1985. Comparison of
chromatographic characteristics of homologous Bence Jones proteins during size -exclusion
chromatography by HPLC and by Sephadex. J. Chromatog. 323: 418 423.
Chang, C. H., M.T. Short, F.A. Westholm, F.J. Stevens, B. C. Wang, W. Furey, A. Solomon,
and M. Schiffer. 1985. A novel arrangement of immunoglobulin variable domains: X ray
crystallographic analysis of the λ chain dimer, Bence Jones protein Loc. Biochemistry
24: 4890 4897.
Schiffer, M., C. H. Chang, and F.J. Stevens. 1985. Formation of an infinite sheet arrangement
dominates the crystallization behavior of λ-type antibody light chains. J. Mol. Biol.
186: 475 478.
Peraino, C., B.A. Carnes, and F.J. Stevens. 1986. Evidence for growth heterogeneity among
different phenotypes in the population of histochemically detectable altered hepatocyte foci
induced in a single neonatal treatment with carcinogen. Carcinogenesis 7: 191 192.
Stevens, F.J. 1986. Analysis of protein protein interaction by simulation of small zone
size exclusion chromatography: application to an antibody antigen association. Biochemistry
25: 981-993.
Stevens, F.J., D.A. LeBuis, W.J. Eisler, and C.F. Ainsworth. 1986. Macromolecular interactions:
application of microcomputer controlled, high speed, size exclusion chromatography. Liquid
Chromatography Gas Chromatography 4: 340 348.
LeBuis, D.A., F.J. Stevens, and W.J. Eisler. 1986. An interface to provide microcomputer control
of a motorized liquid chromatography sample injection valve. Liquid Chromatography Gas
Chromatography 4: 663 666.
Stevens, F.J., J. Jwo, W. Carperos, H. Köhler, and M. Schiffer. 1986. Relationships between
liquid and solid phase antibody association characteristics: implications for the use of
competitive ELISA techniques to map the spatial locations of idiotopes. J. Immunol
137: 1937 1944.
Stevens, F.J. and M. Schiffer. 1987. Immunoglobulin structural diversities and idiotypic
expression. International Rev. Immunol. 2: 357 378.
Stevens, F.J. 1987. Modification of an ELISA based procedure for affinity determination:
correction necessary for use with bivalent antibody. Molec. Immunol. 24: 1055 1060.
Murao, S I., F.J. Stevens, A. Ito, and E. Huberman. 1988. Myeloperoxidase: a myeloid cell
nuclear antigen with DNA binding properties. Proc. Natl. Acad. Sci. USA 85: 1232 1236.
Stevens, F.J., W. Carperos, W.J. Monafo, and N.S. Greenspan. 1988. Size exclusion HPLC
analysis of epitopes. J. Immunol. Methods 108: 271 278.
Peraino, C., B.A. Carnes, F.J. Stevens, E.F. Staffeldt, J.J. Russell, A. Prapuolenis, J.A. Blomquist,
S.D. Vessilinovitch, and R.R. Maronpot. 1988. Comparative developmental and phenotypic
properties of altered hepatocyte foci and hepatic tumors. Cancer Res. 48: 4171 4178.
Stevens, F.J., C. H. Chang, and M. Schiffer. 1988. Dual conformations of an immunoglobulin
light chain dimer: heterogeneity of antigen specificity and idiotope profile may result from
multiple variable domain interaction mechanisms. Proc. Natl. Acad. Sci. USA 85: 6895 6899.
Schiffer, M., C. H. Chang, V.M. Naik, and F.J. Stevens. 1988. Analysis of immunoglobulin
domain interactions: evidence for dominant role of salt bridges. J. Mol. Biol. 203: 799 802.
Schiffer, M., C. Ainsworth, Z. B. Xu, W. Carperos, K. Olsen, A. Solomon, F.J. Stevens,
and C. H. Chang. 1989. The structure of a second crystal form of Bence Jones protein Loc: strikingly different domain associations in two crystal forms of a single protein. Biochemistry
28: 4066 4072.
Stevens, F.J. 1989. Analysis of protein protein interaction by simulation of small zone
size exclusion chromatography: stochastic formulation of kinetic rate contributions to observed
elution characteristics. Biophysical Journal 55: 1155 1167.
Myatt, E.A., P.T.P. Kaumaya, and F.J. Stevens. 1989. Applications of size exclusion HPLC in
the analyses of peptide epitopes. BioChromatography 4: 282 289.
Stevens, F.J. 1990. Fractionation of macromolecules in an alternating transverse electric field:
simulation of the method. J. Biochem. Biophys. Meth. 20: 275 292.
Stevens, F.J., A. Solomon, and M. Schiffer. 1991. Bence Jones proteins: powerful tool for
fundamental study of protein chemistry and pathophysiology. Biochemistry 30: 6803 6805.
Myatt, E.A., F.J. Stevens, and P.B. Sigler. 1991. Self association properties of two dimeric
phospholipases A 2. J. Biol. Chem. 266: 16331 16335.
M. Schiffer, C. H. Chang, and F.J. Stevens. 1992. The functions of tryptophan residues in
membrane proteins. Protein Engineering 5: 213 214.
Stevens, F.J. and E.A. Myatt. 1992. Polymerization of immunoglobulin domains: a model system
for the development of facilitated macromolecular assembly. Nanotechnology 2: 206 213.
Kolmar, H., C. Frisch, G. Kleemann, K. Goetz, F.J. Stevens, and H. J. Fritz. 1994. Dimerization
of Bence Jones proteins: linking the rate of transcription from an Escherichia coli promoter to
the association constant of REIv. Biol. Chem. Hoppe Seyler's Z. 375: 61 70.
Myatt E.A., F.A. Westholm, D. T. Weiss, A. Solomon, M. Schiffer, and F.J. Stevens. 1994.
Pathogenic potential of monoclonal human immunoglobulin light chains: relationship of in vitro
aggregation to in vivo organ deposition. Proc. Natl. Acad. Sci. 91: 3034 3038.
Li, D., F.J. Stevens, M. Schiffer, and L.E. Anderson. 1994. Identification of redox sensitive
cysteines distal to catalytic site in light activated chloroplase enzymes. Biophys. J. 67: 29 35.
Peak, M.J., F.J. Stevens, J.G. Peak, and M.W.W. Adams. 1994. The hyperthermophilic
glycolytic enzyme enolase in the archaeon, Pyrococcus furiosus: comparison with mesophilic
enolases. Arch. Biochm. Biophys. 313: 280 286
Huang, D. B., C. H. Chang, C. Ainsworth, A.T. Brünger, M. Eulitz, A. Solomon, F.J. Stevens,
and M. Schiffer. 1994. Comparison of crystal structures of two homologous proteins: structural
origin of altered domain interactions in immunoglobulin light chain dimers. Biochemistry
33: 14848-14857
Myatt, E.A., F.J. Stevens, and C. Benjamin. 1994. Solution phase binding of monoclonal
antibodies to bee venom phospholipase A2. J. Immunological Methods 177: 35-42.
Wilkins Stevens, P., R. Raffen, D.K. Hanson, Y. L. Deng, M. Berrios Hammond, F.A.
Westholm, C. Murphy, M. Eulitz, R. Wetzel, A. Solomon, M. Schiffer, and F.J. Stevens.
1995. Recombinant immunoglobulin variable domains generated from synthetic genes provide a
system for in vitro characterization of light chain amyloid proteins. Protein Science 4: 421-432.
Anderson, L.E., D. Li, N. Prakash, F.J. Stevens. 1995. Identification of potential
redox sensitive cysteines in cytosolic forms of fructosebiphosphatase and glyceraldehyde 3
phosphate dehydrogenase. Planta 196: 118-124.
Pacold, M.E., L.E. Anderson, D. Li, and F.J. Stevens. 1995. Redox sensitivity and light
modulation of enzyme activity in the rhodophytes Gracilaria tikvahiae and Chondrus crispus.
J. Phycol. 31: 297-301.
Muslin, E.H., D. Li, F.J. Stevens, M. Donnelly, M. Schiffer, and L. Anderson. 1995 Engineering
a domain locking disulfide into a bacterial malate dehydrogenase produces a redox sensitive
enzyme. Biophys. J. 68: 2218-2223.
Pacold, M.E., F.J. Stevens, D. Li, and L.E. Anderson. 1995. The NADP linked
glyceraldehyde 3 P dehydrogenases of Anabena variabilis and Synechocystis PCC 6803 which
lack one of the cysteines found in the higher plant enzymesare not reductively activated.
Photosyn. Res. 43: 125 130.
Paul, S., L. Li, P. Wilkins-Stevens, F.J. Stevens, and A. Solomon. 1995. Natural catalytic
antibodies: peptide hydrolyzing activities of Bence Jones proeins and a VL domain. J. Biol.
Chem 270: 15257-15261.
Stevens, F.J., E.A. Myatt, C.-H. Chang,F.A. Westholm,M. Eulitz, D.T. Weiss, C. Murphy, A.
Solomon, and M. Schiffer. 1995. A molecular model for the formation of amyloid:
Immunoglobulin light chains. Biochemistry 34: 10697-10702.
Boernke, W.E., C. Sanville Millard, S.N. Kakar, V. Jackiw, M. Schiffer, F.J. Stevens, and
M.I. Donnelly. 1995. Stringency of substrate specificity of Escherichia coli malate
dehydrogenase. Arch. Bioch. Biophys 322: 43-52.
Shearer, M.H., F. J. Stevens, F.A. Westholm, H.B. Jenson, T.C. Chanh, K.D. Carey, G.L. White,
and R.C. Kennedy. 1995. Serological crossreactions among primate immunoglobulins. Devel.
and Comp. Immunol. 19: 547-557.
Gallo, G. F. Goni, F. Boctor, R. Vidal, A. Kumar, F.J. Stevens, B. Frangione, and J. Ghiso. 1996
Light chain cardiomyopathy: Structural analysis of the light chain tissue deposits. Am J. Pathol
148: 1397-1406.
Huang,D.-B., C.A. Ainsworth, F.J. Stevens, and M. Schiffer. 1996. Three quaternary structures
for a single protein. Proc. Natl. Acad. Sci. 93: 7017-7021.
Anderson, L., H.C. Huppe, L. Dong, F.J. Stevens. 1996. Identification of a potential redox-
sensitive inter-domain disulfide in the sedoheptulosebisphosphatase of Chlamydomonas
reinhardtii. Plant J. 10: 553-560.
Levine, D., M. Facello, P. Hallstrom, G. Reeder, B. Walenz, and F.J. Stevens. 1997 STALK:
An interactive virtual molecular docking system. Comp. Sci. and Engineer. 4:55-65.
Li, A.D, F.J. Stevens, H.C. Huppe, R. Kersanach, and L.E. Anderson. 1997. Chlamydomanas
reinhardtii NADP-linked glyceraldehyde-3-phosphated dehydrogenase contains the same Cys
residues identified as potentially domain-locking in the higher plant enzyme and is light
activated. Photosyn. Res. 51: 167-177.
Anderson, L.E., A. Dong Li, S.C. Nehrlich, M.H. Hill, and F.J. Stevens. 1997. The cytosolic
fructose bisphosphatase of Brassica napus contains a new potential regulatory disulfide and is
redox-sensitive. Plant Sci. 128: 23-30.
Jiang X, E. Myatt, P. Lykos, and F.J. Stevens. 1997. Interaction between glycosaminoglycans
and immunoglobulin light chains. Biochemistry 36: 13187-13194.
Stevens, F.J., Anderson, L.E., A. Dong Li, and S. Salman Lateef. 1997. Identification of
potential inter-domain disulfides in three higher plant mitochondrial citrate synthases:paradoxical
differences in redox-sensitivity as compared with the animal enzyme Photosyn. Res. 54:
185-197
Anderson, L.E., D. Li, E.H. Muslin, F.J. Stevens, and M. Schiffer. 1997. Predicting redox-
sensitive cysteines in plant enzymes by homology modeling. Comp.Rendu Acad. Sci, Paris
320: 767-781.
Deret, S., J. Chomilier, D.-B. Huang, J.-L. Preud'homme, F.J. Stevens, and P. Aucouturier.
1997. Molecular modelling of immunoglobulin light chains implicates hydrophobic residues in
non-amyloid light chain deposition disease. Protein Engineering 10: 1191-1197.
Anderson, L.E., A.D. Li, and F.J. Stevens. 1998. The enolases of ice plant and arabidopsis
contain a potential disulfide and are redox-sensitive. Phytochem 47: 707-713.
Muslin, E.H., F.J.Stevens, and L.E. Anderson. 1998. New domain-locking disulfides into a
bacterial malate dehydrogenase strengthens evidence for original model of reductive activation of
the chloroplast enzyme. Photosyn. Res. 55: 75-82
Huang, D.-B., C.-H. Chang, C. Ainsworth, G. Johnson, M. Eulitz, A. Solomon, F.J. Stevens, and
M. Schiffer. 1998. Variable domain structure of the human IV light chain Len: high homology
to the murine light chain McPC603. Molec. Immunol.34: 1291-1301.
Raffen, R., P. Wilkins Stevens, M. Schiffer, and F.J. Stevens. 1998. Reengineering
immunoglobulin domain interactions by introduction of charged residues. Protein Engineering
11: 303-309.
Schiffer, M., D.-B. Huang, P.R. Pokkuluri, R. Raffen, G. Johnson, P. Wilkins Stevens, and F.J. Stevens. 1998. A domain flip as a result of a single amino acid substitution.
Structure 6: 1067-1073.
Hellman, R., M. Vanhove, A. Leujeune, F.J. Stevens, and L.M. Hendershot. 1998. The in vivo
association of BiP with newly synthesized proteins is dependent on the rate and stabilty of
folding and not simply on the presence of sequences that can bind to BiP. J. Cell. Biol.
144: 21-30.
Raffen, R., C. Wunschl, P.R. Pokkulur, P. Dave, P. Wilkins Stevens, M. Schiffer, and F.J. Stevens. 1999. Physicochemical consequences of amino acid variations that contribute to
fibril formation by immunoglobulin light chains. Protein Science 8: 509-517.
Deret, S., L. Denoroy, M. Lamarine, R. Vidal, B. Mougenot, B. Frangione, F.J. Stevens, P.M.
Ronco and P. Aucouturier. 1999. Myeloma-associated Fanconi's syndrome: Molecular analyses
of monoclonal immunoglobulin light chains from patients with and without intracellular crystals.
Protein Engineering 12: 363-369.
Stevens, F.J. and Y. Argon. 1999. Pathogenic light chains and the B cell repertoire
Immunology Today 20: 451-457.
Davis, D.P., Khurana, R., S. Meredith, F.J. Stevens, and Y. Argon. 1999. Mapping the major
interaction between binding protein and Ig light chains to sites within the variable domains.
J. Immunol. 163: 3842-3850.
Stevens, F.J. and Y. Argon. 1999. Protein folding in the ER. Semin. Cellular. Devel. Biol. 10:
443-454.
Pokkuluri, P.R., M. Klebig, A. Solomon, F.J. Stevens, and M. Schiffer. 1999. Tertiary structure
of human λ6 light chains. Amyloid: Int. J. Exp. Clin. Invest. 6: 165-171.
Wall, J., M. Schel, C. Murphy, R. Hrncic, M. Klebig, R. Wetzel, F.J. Stevens, and A.
Solomon. 1999. The thermodynamic stability of two λ6 VL proteins correlates with
fibrillogenicity. Biochemistry 38: 14101-14108
Vidal, R., F. Goni, F.J. Stevens, P. Aucouturier, A. Kumar, B. Frangione, J. Ghiso, and G. Gallo.
1999. Somatic mutation of the L12a gene in VκI light chain deposition disease: potential effects
on abberrant protein conformation and deposition. Am. J. Pathol. 155: 2009-2017.
Stevens, F.J. and R. Kisilevsky. 2000. Immunoglobulin light chains, glycosaminoglycans and
amyloid. Cell. Molec. Life Sci. 57: 441-449.
Stevens, F.J. 2000. Four structural risk factors identify most fibril-forming kappa light chains.
Amyloid 7: 200-211.
Pokkuluri, P.R., X. Cai, F.J. Stevens, and M. Schiffer. 2000. Change in dimerization mode by
removal of a single unsatisfied polar residue. Protein Sci. 9: 1852-1855
Setterdahl, A., M. Hirasawa, L.M. Bucher, C.A. Dholakia, P. Jacquot, H. Yards, F. Miller, F.J. Stevens, D.B. Knaff, and L.E.Anderson. 2000. Oxidation-reduction properties of two
engineered redox-sensitive mutant Escherichia coli malate dehydrogenases. Arch. Bioch.
Biophys. 382: 15-21
Davis, D.P., R. Raffen, J.L. Dul, S. Vogen, E.K. Williamson, F.J. Stevens, and Y. Argon. 2000.
Inhibition of amyloid fiber assembly by both BiP and its target peptide. Immunity 13: 433-442.
Stevens, F.J., P.R. Pokkuluri, and M. Schiffer. 2000. Protein conformation and disease:
Pathological consequences of analogous changes in homologous proteins. Biochemistry
39: 15291-15296.
Kim, Y.-S., S.P. Cape, E. Chi, R. Raffen, P. Wilkins-Stevens, F.J. Stevens, M.C. Manning, T.W.
Randolph, A. Solomon, and J.F. Carpenter. 2000. Counteracting effects of renal solutes on
amyloid formation by immunoglobulin light chains. J. Biol. Chem. 276: 1626-1633.
Louise E. Anderson, L.E., A. Dong Li, E. H. Muslin, M. Schiffer, and F.J. Stevens. 2000.
Identifying redox-sensitive extra-chloroplastic enzymes by homology modeling.
Physiol Plantarum 110: 296-303.
Dul, J.L., D.P. Davis, F.J. Stevens, and Y. Argon. 2001. Hsp70 and anti-fibrillogenic
peptides promote degradation and inhibit intracellular aggregation of amyloidogenic light chains.
J. Cell. Biol. 152: 705-716.
Lin, Y-M., R. Raffen, Y. Zhou, M.T. Flavin, and F.J. Stevens. 2001. Amyloid fibril formation in
microwell plates for screening of inhibitors. Amyloid 8: 182-193.
Stevens, F.J. 2001. Caveat receptor: proteomes on display. Comb. Chem. & High Throughput
Screening 4: 599-602.
Davis, D., S. G. Gallo, S.M. Vogen, J.L. Dul, K.L. Sciarretta, A. Kumar, R. Raffen, F.J. Stevens,
and Y. Argon. 2001. Both the environment and somatic mutations govern the aggregation
pathway of pathogenic immunoglobulin light chains. J. Mol. Biol. 313: 1043-1056.
Pokkuluri, P.R., R. Raffen, L. Dieckman, C. Boogaard, F.J. Stevens, and M. Schiffer. 2002.
Increasing protein stability by polar surface residues: domain-wide consequences of interactions
within a loop. Biophysical J. 82: 391-398.
Zavaljevski, N., F.J. Stevens, and J. Reifman. 2002. Support vector machines for protein
classification and identification of key amino acid positions. Bioinformatics 18: 689-696.
Pokkuluri, P.R., M. Gu, X. Cai, R. Raffen, F.J. Stevens, and M. Schiffer. 2002. Factors contributing to decreased protein stability when aspartic acid residues are in β-sheet regions. Protein Sci. 11:1687-1694
Kim, Y.-S., T.W. Randolph, F.J. Stevens, and J.F. Carpenter. 2002. Kinetics and energetics of
assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein.
J. Biol. Chem. 277: 27240-27246.
Kim, Y-S., T.W. Randolph, M.C. Manning, F.J. Stevens, and J.F. Carpenter. 2003. Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation. J. Biol. Chem. 278: 10842-10850.
Vilim, R.B., R.M. Cunningham, B. Lu, P. Kheradpour, and F.J. Stevens. 2004. Fold-specific protein classifier for protein classification. Bioinformatics 20: 839-846.
Coriu, D., A. Dispenzieri, F.J. Stevens, C.L. Murphy, S. Wang, D.T. Weiss and A. Solomon.
2004. Hepatic amyloidosis resulting from deposition of the apolipoprotein A-I variant Leu75Pro.
Amyloid 10: 215-223
Wu, W., J.T. Watson, F.J. Stevens, R.Yousefzai, and L.E. Anderson. 2004. Mass spectrometric
evidence for an alternated disulfide bond in chloroplast fructose bisphosphatase. Photosyn. Res.
79: 189-200.
Gidalevitz, T. C. Biswas, H. Ding, D. Duhovny, H.J. Wolfson, F. Stevens, S. Radford, and Y. Argon. (2004) Identification of the N-terminal peptide binding site of GRP94. J. Biol. Chem. 279: 16543-16552
Stevens, F.J. 2004. Hypothetical structure of SAA: Helical bundle may be
destabilized by proteolytic processing resulting in fibril formation. Amyloid 11: 71-80.
Stevens, F.J. 2004. Efficient recognition of protein fold in the twilight and midnight zones by conservative application of Psi-BLAST: Validation. J. Molecular Recognition. 18: 139-149.
Stevens, F.J., C. Kuemmel, G. Babnigg, and F. Collart. 2004. Efficient recognition of protein fold in the twilight and midnight zones by conservative application of Psi-BLAST: Application. J. Molecular Recognition 18: 150-157.
Stevens, F.J. 2004. Amyloid formation: An emulation of matrix protein assembly? Amyloid
11: 232-244.
Wall, J. , V. Gupta, M. Wilkerson, R. Loris, P. Adams, A. Solomon, F.J. Stevens, and C. Dealwis. (2004) Structural basis of light chain amyloidogenicity: Comparison of the thermodynamic properties, fibrillogenic potential, and tertiary structural features of four V(lambda)6 proteins. J. Molec. Recognition 17: 323-331.
Pirun, M., G. Babnigg, and F.J. Stevens. 2005. Template-based recognition of protein fold within
the midnight and twilight zones of protein sequence similarity. J. Molec. Recogn. 18: 203-212.
Bobrovnik, S.A. and F.J. Stevens. 2004. Evaluation of the intramolecular interaction of
complementary domains, connected with a flexible chain. (in Russian) Ukr. Biochem. J.
76: 148-150.
Yu, C., N. Zavaljevski, F.J. Stevens, K. Yackovich, and J. Reifman. 2005. Classifying noisy
protein sequence data: a case study of immunoglobulin light chains. Bioinformatics (in press).
Ghadge, G.D., L. Wang, K. Sharma, A.L. Monti, V. Bindokas, F.J. Stevens, and R.P. Roos. 2005.
Electroporation of truncated and mutant SOD2 into the chick embryo spinal cord: A critical role
for protein misfolding in neuronal death. J. Neurology (in press)
Stevens, F.J. 2005. Modeling multiple p53 binding sites in BRCA1. (in preparation)
Gu, M., R. Wilton, M. Szpunar, and F.J. Stevens. 2005. Fibril restriction by disulfide bonds:
aggressive fibrillogenesis by RNaseA. (in preparation)
Gu. M., P. Pokkuluri, M. Schiffer, and F.J. Stevens. 2005. Binding of ThioflavinT by non-
fibrillar antibody variable domains. (in preparation)
Stevens, F.J. and A. Solomon. 2005. Amyloidogenic mutations in ApolipoproteinA-1 may be
predictable and segregate into three classes of energetic consequence. (in preparation)
Stevens, F.J. and A. Solomon. 2005. The database of light chain variable domain sequences from
patients with plasma cell diseases: A resource for study of folding disorders of immunoglobulins.
(in preparation).
F. Collart, S. Moy, L. Dieckman, M. Schiffer, J. Fackenthal, G. Green, A. Venkataranian, O.I.
Olopade, and F.J. Stevens. 2005. Generation of functional subunits of BRCA1: Demonstration
of p53 and estrogen receptor binding activities. (in preparation)
