Our Science – Dean Website

Michael Dean, Ph.D.

Selected Publications

1) Sturm A, Cunningham P, Dean M.
The ABC transporter gene family of Daphnia pulex.
BMC Genomics. 2008. In Press. [Journal]

2) Allikmets R, Dean M.
Bringing age-related macular degeneration into focus.
Nat. Genet. 40: 820-1, 2008. [Journal]

3) Potocnik U, Glavac D, Dean M.
Common germline MDR1/ABCB1 functional polymorphisms and haplotypes modify susceptibility to colorectal cancers with high microsatellite instability.
Cancer Genet. Cytogenet. 183: 28-34, 2008. [Journal]

4) Van QN, Issaq HJ, Jiang Q, Li Q, Muschik GM, Waybright TJ, Lou H, Dean M, Uitto J, Veenstra TD.
Comparison of 1D and 2D NMR spectroscopy for metabolic profiling.
J. Proteome Res. 7: 630-9, 2008. [Journal]

5) Meyer-Lindenberg A, Kolachana B, Gold B, Olsh A, Nicodemus KK, Mattay V, Dean M, Weinberger DR.
Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans.
Mol. Psychiatry. Epub ahead of print, 2008. [Journal]

6) Gold B, Kirchhoff T, Stefanov S, Lautenberger J, Viale A, Garber J, Friedman E, Narod S, Olshen AB, Gregersen P, Kosarin K, Olsh A, Bergeron J, Ellis NA, Klein RJ, Clark AG, Norton L, Dean M, Boyd J, Offit K.
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.
Proc. Natl. Acad. Sci. U.S.A. 105: 4340-5, 2008. [Journal]

7) Macias M, Dean M, Atkinson A, Jimenez-Morales S, Garcia-Vazquez FJ, Saldana-Alvarez Y, Ramirez-Bello J, Chavez M, Orozco L.
Spectrum of RB1 gene mutations and loss of heterozygosity in Mexican patients with retinoblastoma: identification of six novel mutations.
Cancer Biomark. 4: 93-9, 2008. [Journal]

8) Chloupkova M, Pickert A, Lee J, Souza S, Trinh YT, Connelly SM, Dumont ME, Dean M, Urbatsch IL.
Expression of 25 human ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity.
Biochemistry. 46: 7992-8003, 2007. [Journal]

9) O'Brien TR, Kachapati K, Zhang M, Bergeron J, Edlin BR, Dean M.
HCV infection clearance with functional or non-functional caspase-12.
Scand. J. Gastroenterol. 42: 416-7, 2007. [Journal]

10) Tan W, Wang Y, Gold B, Chen J, Dean M, Harrison PJ, Weinberger DR, Law AJ.
Molecular cloning of a brain-specific, developmentally regulated Neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.
J Biol Chem. 282: 24343-51, 2007. [Journal]

11) Henrich CJ, Robey RW, Bokesch HR, Bates SE, Shukla S, Ambudkar SV, Dean M, McMahon JB.
New inhibitors of ABCG2 identified by high-throughput screening.
Mol. Cancer Ther. 6: 3271-8, 2007. [Journal]

12) Saugstad OD, Hansen TW, Ronnestad A, Nakstad B, Tollofsrud PA, Reinholt F, Hamvas A, Coles FS, Dean M, Wert SE, Whitsett JA, Nogee LM.
Novel mutations in the gene encoding ATP binding cassette protein member A3 (ABCA3) resulting in fatal neonatal lung disease.
Acta Paediatr. 96: 185-90, 2007. [Journal]

13) Remsberg JR, Lou H, Tarasov SG, Dean M, Tarasova NI.
Structural Analogues of Smoothened Intracellular Loops as Potent Inhibitors of Hedgehog Pathway and Cancer Cell Growth.
J Med Chem. 50: 4534-8, 2007. [Journal]

14) Lou H, Dean M.
Targeted therapy for cancer stem cells: the patched pathway and ABC transporters.
Oncogene. 26: 1357-60, 2007. [Journal]

15) Henrich CJ, Bokesch HR, Dean M, Bates SE, Robey RW, Goncharova EI, Wilson JA, McMahon JB.
A high-throughput cell-based assay for inhibitors of ABCG2 activity.
J Biomol Screen. 11: 176-83, 2006. [Journal]

16) Dean M.
Cancer stem cells: redefining the paradigm of cancer treatment strategies.
Mol. Interv. 6: 140-8, 2006. [Journal]

17) Javanbakht H, An P, Gold B, Petersen DC, O'Huigin C, Nelson GW, O'Brien SJ, Kirk GD, Detels R, Buchbinder S, Donfield S, Shulenin S, Song B, Perron MJ, Stremlau M, Sodroski J, Dean M, Winkler C.
Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.
Virology. 354: 15-27, 2006. [Journal]

18) Si Z, Vandegraaff N, O'huigin C, Song B, Yuan W, Xu C, Perron M, Li X, Marasco WA, Engelman A, Dean M, Sodroski J.
Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.
Proc. Natl. Acad. Sci. U.S.A. 103: 7454-9, 2006. [Journal]

19) Annilo T, Chen ZQ, Shulenin S, Costantino J, Thomas L, Lou H, Stefanov S, Dean M.
Evolution of the vertebrate ABC gene family: Analysis of gene birth and death.
Genomics. 88: 1-11, 2006. [Journal]

20) Hageman GS, Hancox LS, Taiber AJ, Gehrs KM, Anderson DH, Johnson LV, Radeke MJ, Kavanagh D, Richards A, Atkinson J, Meri S, Bergeron J, Zernant J, Merriam J, Gold B, Allikmets R, Dean M.
Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.
Ann. Med. 38: 592-604, 2006. [Journal]

21) Guo XC, Scott K, Liu Y, Dean M, David V, Nelson GW, Johnson RC, Dilks HH, Lautenberger J, Kessing B, Martenson J, Guan L, Sun S, Deng H, Zheng Y, de The G, Liao J, Zeng Y, O'Brien SJ, Winkler CA.
Genetic factors leading to chronic Epstein-Barr virus infection and nasopharyngeal carcinoma in South East China: study design, methods and feasibility.
Hum Genomics. 2: 365-75, 2006. [Journal]

22) Bacolla A, Collins JR, Gold B, Chuzhanova N, Yi M, Stephens RM, Stefanov S, Olsh A, Jakupciak JP, Dean M, Lempicki RA, Cooper DN, Wells RD.
Long homopurine*homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region.
Nucleic Acids Res. 34: 2663-75, 2006. [Journal]

23) Polgar O, Ozvegy-Laczka C, Robey RW, Morisaki K, Okada M, Tamaki A, Koblos G, Elkind NB, Ward Y, Dean M, Sarkadi B, Bates SE.
Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization.
Biochemistry. 45: 5251-60, 2006. [Journal]

24) Kachapati K, O'Brien TR, Bergeron J, Zhang M, Dean M.
Population distribution of the functional caspase-12 allele.
Hum. Mutat. 27: 975, 2006. [Journal]

25) Wang Z, Stalcup LD, Harvey BJ, Weber J, Chloupkova M, Dumont ME, Dean M, Urbatsch IL.
Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8.
Biochemistry. 45: 9929-39, 2006. [Journal]

26) Garmany TH, Moxley MA, White FV, Dean M, Hull WM, Whitsett JA, Nogee LM, Hamvas A.
Surfactant composition and function in patients with ABCA3 mutations.
Pediatr. Res. 59: 801-5, 2006. [Journal]

27) Goldstone JV, Hamdoun A, Cole BJ, Howard-Ashby M, Nebert DW, Scally M, Dean M, Epel D, Hahn ME, Stegeman JJ.
The chemical defensome: environmental sensing and response genes in the Strongylocentrotus purpuratus genome.
Dev. Biol. 300: 366-84, 2006. [Journal]

28) Chen ZQ, Dong J, Ishimura A, Daar I, Hinnebusch AG, Dean M.
The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors.
J. Biol. Chem. 281: 7452-7, 2006. [Journal]

29) Robey RW, Fetsch PA, Polgar O, Dean M, Bates SE.
The livestock photosensitizer, phytoporphyrin (phylloerythrin), is a substrate of the ATP-binding cassette transporter ABCG2.
Res. Vet. Sci. 81: 345-9, 2006. [Journal]

30) Li X, Gold B, O'huigin C, Diaz-Griffero F, Song B, Si Z, Li Y, Yuan W, Stremlau M, Mische C, Javanbakht H, Scally M, Winkler C, Dean M, Sodroski J.
Unique features of TRIM5alpha among closely related human TRIM family members.
Virology. 2006. [Journal]

31) Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, Gehrs K, Cramer K, Neel J, Bergeron J, Barile GR, Smith RT, Hageman GS, Dean M, Allikmets R.
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration.
Nat. Genet. 38: 458-62, 2006. [Journal]

32) Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, Hageman JL, Stockman HA, Borchardt JD, Gehrs KM, Smith RJ, Silvestri G, Russell SR, Klaver CC, Barbazetto I, Chang S, Yannuzzi LA, Barile GR, Merriam JC, Smith RT, Olsh AK, Bergeron J, Zernant J, Merriam JE, Gold B, Dean M, Allikmets R.
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration.
Proc . Natl. Acad. Sci. USA. 102: 7227-32, 2005. [Journal]

33) Bullard JE, Wert SE, Whitsett JA, Dean M, Nogee LM.
ABCA3 mutations associated with pediatric interstitial lung disease.
Am. J. Respir. Crit. Care Med. 172: 1026-31, 2005. [Journal]

34) Ali IU, Luke BT, Dean M, Greenwald P.
Allellic variants in regulatory regions of cyclooxygenase-2: association with advanced colorectal adenoma.
Br. J. Cancer. 93: 953-9, 2005. [Journal]

35) Dean M, Annilo T.
Evolution of the ATP-Beinding Cassette (ABC) Transporter Superfamily in Vertebrates.
Annu. Rev. Genomics Hum. Genet. 6: 123-42, 2005. Full Text Article. [Journal]

36) Huang WY, Chatterjee N, Chanock S, Dean M, Yeager M, Schoen RE, Hou LF, Berndt SI, Yadavalli S, Johnson CC, Hayes RB.
Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma.
Cancer Epidemiol. Biomarkers Prev. 14: 152-7, 2005. [Journal]

37) Ng D, Stavrou T, Liu L, Taylor MD, Gold B, Dean M, Kelley MJ, Dubovsky EC, Vezina G, Nicholson HS, Byrne J, Rutka JT, Hogg D, Reaman GH, Goldstein AM.
Retrospective family study of childhood medulloblastoma.
Am. J. Med. Genet. A. 134: 399-403, 2005. [Journal]

38) Petersen DC, Glashoff RH, Shrestha S, Bergeron J, Laten A, Gold B, van Rensburg EJ, Dean M, Hayes VM.
Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population.
J. Acquir. Immune Defic. Syndr. 40: 521-6, 2005. [Journal]

39) Song B, Gold B, O'Huigin C, Javanbakht H, Li X, Stremlau M, Winkler C, Dean M, Sodroski J.
The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.
J. Virol. 79: 6111-21, 2005. [Journal]

40) Dean M.
The genetics of ATP-binding cassette transporters.
Meth. Enzymol. 400: 409-29, 2005. [Journal]

41) Dean M, Fojo T, Bates S.
Tumour stem cells and drug resistance.
Nat. Rev. Cancer. 5: 275-84, 2005. [Journal]

42) Dong HF, Wigmore K, Carrington MN, Dean M, Turpin JA, Howard OM.
Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5.
Genes Immun. 6: 609-19, 2005. [Journal]

43) Shulenin S, Nogee LM, Annilo T, Wert SE, Whitsett JA, Dean M.
ABCA3 gene mutations in newborns with fatal surfactant deficiency.
N. Engl. J. Med. 350: 1296-303, 2004. [Journal]

44) Yang XR, Wacholder S, Xu Z, Dean M, Clark V, Gold B, Brown LM, Stone BJ, Fraumeni JF, Caporaso NE.
CYP1A1 and GSTM1 polymorphisms in relation to lung cancer risk in Chinese women.
Cancer Lett. 214: 197-204, 2004. [Journal]

45) Ogino S, Wilson RB, Gold B, Hawley P, Grody WW.
Bayesian analysis for cystic fibrosis risks in prenatal and carrier screening.
Genet. Med. 6: 439-49, 2004. [Journal]

46) Duh F, Fivash M, Moody M, Li L, Guo X, Stanbridge E, Dean M, Voevoda M, Hu L, Kashuba V, Zabarovsky E, Qian C, Godbole S, Tean Teh B, Lerman M.
Characterization of a new SNP c767A/T (Arg222Trp) in the candidate TSG FUS2 on human chromosome 3p21.3: prevalence in Asian populations and analysis of assocaiation with nasopharyngeal cancer.
Mol. Cell Probes. 18: 39-44, 2004. [Journal]

47) Annilo T, Dean M.
Degeneration of an ATP-binding cassette transporter gene, ABCC13, in different mammalian lineages.
Genomics. 84: 34-46, 2004. [Journal]

48) Gold B, Kalush F, Bergeron J, Scott K, Mitra N, Wilson K, Ellis N, Huang H, Chen M, Lippert R, Halldorsson BV, Woodworth B, White T, Clark AG, Parl FF, Broder S, Dean M, Offit K.
Estrogen receptor genotypes and haplotypes associated with breast cancer risk.
Cancer Res. 64: 8891-900, 2004. [Journal]

49) Landi MT, Goldstein AM, Tsang S, Munroe D, Modi W, Ter-Minassian M, Steighner R, Dean M, Metheny N, Staats B, Agatep R, Hogg D, Calista D.
Genetic susceptibility in familial melanoma from northeastern Italy.
J. Med. Genet. 41: 557-66, 2004. [Journal]

50) Clark VJ, Dean M.
Haplotype structure and linkage disequilibrium in chemokine and chemokine receptor genes.
Hum. Genomics. 1: 255-73, 2004. [Journal]

51) Belfer I, Buzas B, Hipp H, Dean M, Evans C, Lorincz I, Max MB, Goldman D.
Haplotype structure of inflammatory cytokines genes (IL1B, IL6 and TNF/LTA) in US Caucasians and African Americans.
Genes Immun. 5: 505-12, 2004. [Journal]

52) Polgar O, Robey RW, Morisaki K, Dean M, Michejda C, Sauna ZE, Ambudkar SV, Tarasova N, Bates SE.
Mutational analysis of ABCG2: role of the GXXXG motif.
Biochemistry. 43: 9448-56, 2004. [Journal]

53) Potocnik U, Ferkolj I, Glavac D, Dean M.
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis.
Genes Immun. 5: 530-9, 2004. [Journal]

54) Tarnay JN, Szeri F, Ilias A, Annilo T, Sung C, Le Saux O, Varadi A, Dean M, Boyd CD, Robinow S.
The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.
Insect. Mol. Biol. 13: 539-48, 2004. [Journal]

55) Chen ZQ, Annilo T, Shulenin S, Dean M.
Three ATP-binding cassette transporter genes, ABCA14, ABCA15, and ABCA16, form a cluster on mouse Chromosome 7F3.
Mamm. Genome. 15: 335-43, 2004. [Journal]

56) Collins JR, Stephens RM, Gold B, Long B, Dean M, Burt SK.
An exhaustive DNA micro-satellite map of the human genome using high performance computing.
Genomics. 82: 10-9, 2003. [Journal]

57) Dean M.
Approaches to identify genes for complex human diseases: lessons from Mendelian disorders.
Hum Mutat. 22: 261-74, 2003. [Journal]

58) Annilo T, Chen ZQ, Shulenin S, Dean M.
Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.
Mamm. Genome. 14: 7-20, 2003. [Journal]

59) Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, Zaitsev E, Gold B, Goldman D, Dean M, Lu B, Weinberger DR.
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
Cell. 112: 257-69, 2003. [Journal]

60) Ravnik-Glavac M, Atkinson A, Glavac D, Dean M.
DHPLC screening of cystic fibrosis gene mutations.
Hum Mutat. 19: 374-83, 2002. [Journal]

61) Annilo T, Shulenin S, Chen ZQ, Arnould I, Prades C, Lemoine C, Maintoux-Larois C, Devaud C, Dean M, Denèfle P, Rosier M.
Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34.
Cytogenet Genome Res. 98: 169-76, 2002. [Journal]

62) Honjo Y, Morisaki K, Huff LM, Robey RW, Hung J, Dean M, Bates SE.
Single-Nucleotide Polymorphism (SNP) Analysis in the ABC Half-Transporter ABCG2 (MXR/BCRP/ABCP1).
Cancer Biol Ther. 1: 696-702, 2002. [Journal]

63) Prades C, Arnould I, Annilo T, Shulenin S, Chen ZQ, Orosco L, Triunfol M, Devaud C, Maintoux-Larois C, Lafargue C, Lemoine C, Denèfle P, Rosier M, Dean M.
The human ATP binding cassette gene ABCA13, located on chromosome 7p12.3, encodes a 5058 amino acid protein with an extracellular domain encoded in part by a 4.8-kb conserved exon.
Cytogenet Genome Res. 98: 160-8, 2002. [Journal]

64) Honjo Y, Hrycyna CA, Yan QW, Medina-Pérez WY, Robey RW, van de Laar A, Litman T, Dean M, Bates SE.
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.
Cancer Res. 61: 6635-9, 2001. [Journal]

65) Mickley L, Jain P, Miyake K, Schriml LM, Rao K, Fojo T, Bates S, Dean M.
An ATP-binding cassette gene (ABCG3) closely related to the multidrug transporter ABCG2 (MXR/ABCP) has an unusual ATP-binding domain.
Mamm Genome. 12: 86-8, 2001. [Journal]

66) Shulenin S, Schriml LM, Remaley AT, Fojo S, Brewer B, Allikmets R, Dean M.
An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus.
Cytogenet Cell Genet. 92: 204-8, 2001. [Journal]

67) Annilo T, Tammur J, Hutchinson A, Rzhetsky A, Dean M, Allikmets R.
Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4.
Cytogenet Cell Genet. 94: 196-201, 2001. [Journal]

68) Clark VJ, Metheny N, Dean M, Peterson RJ.
Statistical estimation and pedigree analysis of CCR2-CCR5 haplotypes.
Hum Genet. 108: 484-93, 2001. [Journal]

69) Dean M, Hamon Y, Chimini G.
The human ATP-binding cassette (ABC) transporter superfamily.
J Lipid Res. 42: 1007-17, 2001. [Journal]

70) Dean M, Rzhetsky A, Allikmets R.
The human ATP-binding cassette (ABC) transporter superfamily.
Genome Res. 11: 1156-66, 2001. [Journal]

71) Denfle P, Allikmets R, Arnould I, Dean M, Prades C, Rosier M, inventor; DHHS, assignee.
Nucleic acid and amino acid sequences for ATP-binding cassette transporter and methods of screening for agents that modify ATP-binding cassette transporter.
Patent Pending, Filed in 2001. Application No. 10/087,782. Pending [Patent]

72) Denfle P, Allikmets R, Arnould I, Dean M, Prades C, Rosier M, inventor; DHHS, assignee.
Nucleic Acids Of The Human Abca12 Gene, Vectors Containing Such Nucleic Acids And Uses Thereof.
Patent Pending, Filed in 2001. Application No. 10/072,900. Pending [Patent]

73) Denfle P, Allikmets R, Arnould I, Dean M, Prades C, Rosier M, inventor; DHHS, assignee.
Nucleic Acids Of The Human Abcc12 Gene, Vector Containing Such Nucleic Acids And Uses Thereof.
Patent Pending, Filed in 2001. Application No. 10/090,280. Pending [Patent]

74) Hageman G, Allikmets R, Dean M, Gold A, inventor; DHHS, assignee.
Variants In Complement Regulatory Genes Predict Age-related Macular Degeneration.
Patent Pending, Filed in 2006. Application No. 11/894,784; 11/706,074. Pending [Patent]

75) Dean M, Allikmets R, Gold A, Hageman G, inventor; DHHS, assignee.
Variants in complement regulatory genes predict age-related macular degeneration.
Patent Pending, Filed in 2006. Application No. 11/706,154. Pending [Patent]

76) Dean M, Allikmets R, Bates S, Fojo A, inventor; DHHS, assignee.
ATP-binding cassette protein responsible for cytotoxin resistance.
US Patent: 7,138,493. 2006. [Patent]

77) Dean M, Allikmets R, Hutchinson A, inventor.
ATP-binding transporter (ABC7) and methods for detection of anemia and ataxia.
US Patent: 6,867,017. 2005. [Patent]

78) Dean M, Hahn H, Wicking C, Christiansen J, Chidambaram A, Vorechovsky I, Lindstrom E, Unden A, Gilles S, Negus K, Smyth I, Pressman C, Leffell D, Gerrard B, Goldstein A, Wainwright B, Toftgard R, Trench G, Bale A, Zaphiropoulos P, Gailani M, Shanley S, inventor; DHHS, assignee.
Basal cell carcinoma tumor supressor gene.
US Patent: 6,552,181. 2003. [Patent]

79) Dean M, O'Brien S, Smith M, Carrington M, inventor.
Delayed progression to aids by a missense allele of the CCR2 gene.
US Patent: 6,600,030. 2003. [Patent]

80) Allikmets R, Anderson K, Dean M, Leppert M, Lewis R, Li Y, Lupski J, Nathans J, Ratner A, Shroyer N, Singh N, Smallwood P, Sun H, inventor.
Methods of gene therapy using nucleic acid sequences for ATP-binding cassette transporter.
US Patent: 7,192,579. 2007. [Patent]

81) Allikmets R, Anderson K, Dean M, Leppert M, Lewis R, Li Y, Lupski J, Nathans J, Ratner A, Shroyer N, Singh N, Smallwood P, Sun H, inventor.
Methods of screening and diagnostics using ATP-binding cassette transporter.
US Patent: 7,189,511. 2007. [Patent]

82) Allikmets R, Anderson K, Dean M, Leppert M, Lewis R, Li Y, Lupski J, Nathans J, Ratner A, Shroyer N, Singh N, Smallwood P, Sun H, inventor.
Nucleic acid and amino acid sequences for ATP-binding cassette transporter and methods of screening for agents that modify ATP-binding cassette transporter.
US Patent: 7,141,420. 2006. [Patent]

83) Allikmets R, Anderson K, Dean M, Leppert M, Lewis R, Li Y, Lupski J, Nathans R, Rattner A, Shroyer N, Singh N, Smallwood P, Sun H, inventor; University of Utah Research Foundation; Baylor College of Medicine; Johns Hopkins University; and DHHS, assignee.
Nucleic acid and amino acid sequences for ATP-binding cassette transporter and methods of screening for agents that modify ATP-binding cassette transporter.
US Patent: 6,713,300. 2004. [Patent]

84) Rosier M, Prades C, Arnould I, Dean M, Allikmets R, Denefle P, inventor; Aventis Pharma S.A., assignee.
Nucleic acids of the human ABCC11 gene, vectors containing such nucleic acids and uses thereof.
US Patent: 6,893,841. 2005. [Patent]

This page was last updated on 11/25/2008.