Singh S, Singh N, Singhal S, Balooni V; International Conference on AIDS.
Int Conf AIDS. 2002 Jul 7-12; 14: abstract no. ThPeB7274.
A.I.I.M.S., New Delhi, India
BACKGROUND: Tuberculosis is a major health problem particularly in developing countries. World Health Organization estimates that 8 million people contact tuberculosis every year with 2 million deaths. India is hardest hit country, particularly, after AIDS epidemic. Now in India, tuberculosis is the leading cause of AIDS associated mortality in India. There are also reports that prevalence of HIV is more in TB clinic attendees. METHODS: Prompted with these reports we conducted a study to find out the prevalence of HIV infection in the North Indian patients. Six hundred and twenty patients with Mycobacterium tuberculosis diseases were included in this study. All the patients were counselled and after informed consent their blood samples were withdrawn and sera separated. The serum samples were divided into two major groups; the pulmonary TB (400) and extra-pulmonary TB (220). The later group was further subdivided into 4 subgroups and comprised of patients of TB lymphadenitis (150), tubercular meningitis (50) and milliary tuberculosis (20). Serum samples were tested for HIV antibodies. RESULTS: Out of 620 serum samples, 33 (5.3%) were found HIV-1 positive. None was HIV-2 positive. The data indicated that seroprevalence of HIV was high in pulmonary tuberculosis cases [6.25% (25/400)] as compared to 3.6% (8/220) in extra-pulmonary cases. In the later group too the highest prevalence [10% (2/20)] was in milliary tuberculosis patients followed by TB meningitis [4% (2/50)] and least in tubercular lymphadenitis cases [2.7% (4/150)]. CONCLUSIONS: The study indicates that though HIV prevalence in TB clinic attendees was more than HIV negative clients, the prevalence rates in our study was significantly less than the studies reported from South and western India.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Developing Countries
- Disease Outbreaks
- HIV
- HIV Infections
- HIV Seronegativity
- HIV Seropositivity
- HIV-1
- Humans
- India
- Prevalence
- Seroepidemiologic Studies
- Tuberculosis
- Tuberculosis, Pulmonary
- World Health Organization
- epidemiology
- immunology
Other ID:
UI: 102254716
From Meeting Abstracts