Curriculum Vitae: John Rinzel

Address

9190 Wisconsin Ave.
Suite 350
Bethesda, MD 20814
Phone: (301) 496-4325
Fax: (301) 402-0535

Education

1967 B. S. (Engineering Science) - University of Florida

1968 M. S. (Applied Mathematics) - New York University

1973 Ph.D. (Applied Mathematics) - New York University

Professional Appointments

1968 - 1970 &
1973 - 1975 Mathematician, Division of Computer Research and Technology, NIH

1975 - 1981 Research Mathematician, Mathematical Research Branch, NIADDK, NIH

1981 - Chief, Mathematical Research Branch, NIDDK, NIH

1975 - 1979 Visiting Lecturer of Mathematical Biology, Dept. of Mathematics, Univ. of Maryland

1989 - Adjunct Professor of Mathematical Biology - Dept. of Mathematics, Univ. of Maryland

1995 - Adjunct Professor Dept. of Biomedical Engineering, Johns Hopkins University

Visiting Appointments

Department of Mathematics, University British Columbia, 1980, January-June.
Center of Math Biology, University of Oxford, 1984, June-July.
Institute of Nonlinear Science, University CA - San Diego, 1986, July-August.

Professional Activities

Committees: AMS-SIAM Committee on Mathematics in the Life Sciences, 1983 -

NIDDK, Assembly of Scientists, President, 1988

NIH Advisory Committee on Computer Usage, 1988 - 1994

NIMH Study Section, Computational Neuroscience (ad hoc. member), 1991 - 1992

Program Committee: Computation and Neural Systems Meetings, 1993 - 1995
Editorial Boards: Math Biosci, 1975 - ; SIAM J. Applied Math., 1976 - 1983, 1986 - 1994

J Math Biology, 1980 - ; Computers in Biol & Med, 1981 - 1986

J Theoret Biol, 1987 - 1994

IMA J Math Applied in Med & Biol, 1985 - 1994

J Computational Neuroscience (Managing Co-editor), 1994 -

Symposia Organized:

Mathematical Modeling and Computation in Physiology, FASEB, 1978.
Workshop on Mathematical Neurobiology (w/ R. Miura), Univ. of British Columbia, 1980.
Models in Neuro and Developmental Biology, Amer. Math. Soc., 1980.
Theoretical Trends in Neurobiology (w/ H. Lecar), FASEB, 1984.
Gordon Research Conf. on Theoretical Biol. and Biomathematics, (w/ D. Lauffenburger), 1986.
NATO Advanced Research Workshop on Theoretical Models for Cell to Cell Signaling

(w/ A. Goldbeter and L. Segel), Belgium, 1988.
NIH Symposium Honoring Wilfrid Rall: "Insights into Dendritic Function from Theory and

Experiment" (w/ G. Shepherd), 1988.
Summer Program in Mathematical Physiology (w/ others), Math Sciences Res Inst, Berkeley,

July-August, 1992.
Symposium on Bursting Oscillations (w/ D. Terman) SIAM Conf on Dynamical Systems, Snowbird, 1992.

Societies:

SIAM, Soc Neuroscience, AAAS.

Partial List of Invited Lectures

Gordon Research Conference on Theoretical Biology and Biomathematics: 1972, 1973, 1979, 1984
FASEB Meeting: Various physiological symposia - 1974, 1978, 1984, 1987
8th Dundee Conference on Theory of Ordinary and Partial Differential Equations, Dundee, 1984.
Bat-Sheva Seminar on Nonlinear Analysis of Neurobiological Processes, Jerusalem, 1985.
International Symposium on Mathematical Biology, Kyoto, 1985.
International Congress of Mathematicians, Berkeley, 1986.
International Workshop on Biomathematics, Capri, Italy, 1987.
Society for Mathematical Biology Symposium: Classics of Theoretical Biology, Oxford, 1989.
Annual Meeting: Computational Neuroscience, CNS*92, San Francisco, 1992.
Neural Networks: a New Biotechnology From Neuroscience, INNS Satellite Symposium
Annual Meeting Soc for Neuroscience, Washington, DC, 1993.

Selected Publications

Rinzel J, Keller JB: Traveling wave solutions of a nerve conduction equation.
Biophysical J.,13:1313-1337, 1973.

Rinzel J, Rall W: Transient response in a dendritic neuron model for current injected at one branch. Biophysical J.,14:759-790, 1974.

Guttman R, Lewis S, Rinzel J: Control of repetitive firing in squid axon membrane as a model for a neuron oscillator. J. Physiol. (Lond.), 305:377-397, 1980.

Ermentrout GB, Rinzel J: Beyond a pacemaker's entrainment limit: Phase walk through. Am. J. Physiol. 246 (Regulatory Integrative Comp. Physiol. 15: R102-R106, 1984.

Miller JP, Rall W, Rinzel J: Synaptic amplification by active membrane in dendritic spines. Brain Res. 325:325-330, 1985.

Sherman A, Rinzel J, Keizer J: Emergence of organized bursting in clusters of pancreatic Beta-cells by channel sharing. Biophys. J. 54:411-425, 1988.

Baer SM, Erneux T, Rinzel J: The slow passage through a Hopf bifurcation: delay, memory effects and resonance. SIAM J. Appl. Math. 49:55-71, 1989.

Baer SM, Rinzel J: Propagation of dendritic spikes mediated by excitable spines: a continuum theory. J. Neurophys. 65:874-890, 1991.

Wang X-J, Rinzel J, Rogawski MA: A model of the T-type calcium current and the low-threshold spike in thalamic neurons. J. Neurophys. 66:839-850, 1991.

Wang X-J, Rinzel J: Alternating and synchronous rhythms in reciprocally inhibitory model neurons. Neural Computation 4:84-97, 1992.

Smolen P, Rinzel J, Sherman A: Why pancreatic islets burst but single Beta-cells do not: The heterogeneity hypothesis. Biophysical J 64:1668-1680, 1993.

Li Y-X, Rinzel J, Keizer J, Stanjilkovic SS: Modeling agonist-induced calcium signaling in pituitary gonadotrophs based on calcium-gated InsP3 receptor channel activity. Proc Natl Acad Sci USA 91:58-62, 1994.

Pinsky PF, Rinzel J: Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci 1:39-60, 1994.

Wang X-J, Golomb D, Rinzel J: Emergent spindle oscillations and intermittent burst firing in a thalamic model: Specific neuronal mechanisms. Proc Natl Acad Sci USA 92:5577-5581, 1995.

1967	B. S. (Engineering Science) - University of Florida
1968	M. S. (Applied Mathematics) - New York University
1973	Ph.D. (Applied Mathematics) - New York University

1968 - 1970 & 1973 - 1975	Mathematician, Division of Computer Research and Technology, NIH
1975 - 1981	Research Mathematician, Mathematical Research Branch, NIADDK, NIH
1981 -	Chief, Mathematical Research Branch, NIDDK, NIH
1975 - 1979	Visiting Lecturer of Mathematical Biology, Dept. of Mathematics, Univ. of Maryland
1989 -	Adjunct Professor of Mathematical Biology - Dept. of Mathematics, Univ. of Maryland
1995 -	Adjunct Professor Dept. of Biomedical Engineering, Johns Hopkins University

Committees:	AMS-SIAM Committee on Mathematics in the Life Sciences, 1983 -
	NIDDK, Assembly of Scientists, President, 1988
	NIH Advisory Committee on Computer Usage, 1988 - 1994
	NIMH Study Section, Computational Neuroscience (ad hoc. member), 1991 - 1992
	Program Committee: Computation and Neural Systems Meetings, 1993 - 1995
Editorial Boards:	Math Biosci, 1975 - ; SIAM J. Applied Math., 1976 - 1983, 1986 - 1994
	J Math Biology, 1980 - ; Computers in Biol & Med, 1981 - 1986
	J Theoret Biol, 1987 - 1994
	IMA J Math Applied in Med & Biol, 1985 - 1994
	J Computational Neuroscience (Managing Co-editor), 1994 -