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Title Measurements and monitoring of phototherapy in newborn jaundice
Creator/Author Sisson, T.R.
Publication Date1982 May 01
OSTI IdentifierOSTI ID: 6942553
Other Number(s)CODEN: MLISB
Resource TypeJournal Article
Resource RelationMed. Instrum. (Arlington, Va.) ; Vol/Issue: 16:3
Subject550603 -- Medicine-- External Radiation in Therapy-- (1980-); ;BILIRUBIN-- PHOTOSENSITIVITY;JAUNDICE-- RADIOTHERAPY; EVALUATION;EXCRETION;NEONATES;PHOTOCHEMICAL REACTIONS;VISIBLE RADIATION
Related SubjectAZOLES;CARBOXYLIC ACIDS;CHEMICAL REACTIONS;CLEARANCE;ELECTROMAGNETIC RADIATION;HETEROCYCLIC ACIDS;HETEROCYCLIC COMPOUNDS;MEDICINE;NUCLEAR MEDICINE;ORGANIC ACIDS;ORGANIC COMPOUNDS;ORGANIC NITROGEN COMPOUNDS;PATHOLOGICAL CHANGES;PIGMENTS;PYRROLES;RADIATIONS;RADIOLOGY;SENSITIVITY;SYMPTOMS;THERAPY
Description/Abstract Hyperbilirubinemia in the newborn (neonatal jaundice) may cause irreversible brain damage if plasma concentrations of bilirubin exceed the number of binding sites on albumin and other blood components.^Phototherapy or exchange transfusions to prevent the excessive rise in concentration of the pigment should be instituted in appropriate clinical situations.^In phototherapy, the jaundiced infant is exposed to visible light containing the wavelength (about 450 nm) bilirubin will absorb.^Because bilirubin is quite photolabile and will readily isomerize in vivo, it is rapidly converted to excretable forms.^The effectiveness of this therapy, however, depends upon the maintenance of adequate radiant flux in the required wavelength.^Energy output and spectral distributions of phototherapy lamps must be measured.^The long-term effects of irradiation of newborn infants over several days are not yet known.
Country of PublicationUnited States
LanguageEnglish
FormatPages: 157-159
System Entry Date2001 May 13

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