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Treponema denticola Search Results

Record: 1 of 1 MiniMap

Gene ID:TDE2063DNA Molecule Name: 1 GenBank ID: 42527567Gene Name: feoB Definition: ferrous iron transport protein BCellular Location: Inner membrane, Cytoplasm [Evidence]Gene Start: 2091354Gene Stop: 2088523Gene Length: 2832Molecular Weight*: 105124pI*:Net Charge*:EC: Functional Class: Transport and binding proteins; Iron Gene Ontology:Pathway: pathway tableSecondary Evidence: Andrews SC, Robinson AK, Rodríguez-Quiñones F. Bacterial iron homeostasis. FEMS Microbiol Rev. 2003 Jun;27(2-3):215-37. PMID: 12829269 Edwards KJ, Rogers DR, Wirsen CO, McCollom TM. Isolation and characterization of novel psychrophilic, neutrophilic, Fe-oxidizing, chemolithoautotrophic alpha- and gamma-proteobacteria from the deep sea. Appl Environ Microbiol. 2003 May;69(5):2906-13. PMID: 12732565 Marlovits TC, Haase W, Herrmann C, Aller SG, Unger VM. The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria. Proc Natl Acad Sci U S A. 2002 Dec;99(25):16243-8. PMID: 12446835Comment:View in HOMD Genome ViewerBlast Summary: PSI-Blast Search TDE2063 has significant similarity to the Treponema pallidum gene TP0689 (7e-05). TDE2063 has significant similarity to the Borrelia burgdorferi gene 15595126 (2e-06).Top Blast Hits: Updated monthly Click here to view the entire PsiBlast results. gi|42527567|ref|NP_972665.1| ferrous iron transport protein... 1786 0.0 gi|94987525|ref|YP_595458.1| Fe2+ transport system protein ... 363 4e-98 gi|146329115|ref|YP_001209067.1| ferrous iron transport pro... 345 7e-93 gi|145620567|ref|ZP_01776594.1| ferrous iron transport prot... 326 4e-87 gi|69245956|ref|ZP_00603728.1| Ferrous iron transport prote... 321 2e-85 gi|39998358|ref|NP_954309.1| ferrous iron transport protein... 315 8e-84 gi|110800234|ref|YP_695571.1| ferrous iron transport protei... 311 2e-82 gi|118579231|ref|YP_900481.1| ferrous iron transport protei... 308 1e-81 gi|156858480|gb|EDO51911.1| hypothetical protein BACUNI_044... 307 2e-81 gi|118745171|ref|ZP_01593151.1| ferrous iron transport prot... 305 1e-80COGS Summary: COGS Search BeTs to clades of COG0370 COG name: Fe2+ transport system Functional Class:� P The phylogenetic pattern of COG0370 is a-m-k--qvd-l-cefg-s-uj---- Number of proteins in this genome belonging to this COG isBlocks Summary: Blocks Search Significant hit ( 2.1e-51) to 4/4 blocks of the IPB003373 family, which is described as "Ferrous iron transport protein B". Interpro entry for IPR003373. IPB003373A 35-77 1.1e-18 IPB003373B 85-117 1.2e-13 IPB003373C 123-159 2e-08 IPB003373D 357-384 2.7e-06 Significant hit ( 3.4e-12) to 1/1 blocks of the IPB000765 family, which is described as "GTP1/OBG family". Interpro entry for IPR000765. IPB000765 6-49 3.4e-12ProDom Summary: Protein Domain Search Residues 8 to 93 match (5e-22) PD:PD000414 which is described as GTP-BINDING PROTEOME COMPLETE PROBABLE TRNA ENGA REPEAT IRON GTPASE HOMOLOG Residues 422 to 537 match (4e-21) PD:PD005672 which is described as COMPLETE PROTEOME IRON FERROUS B TRANSMEMBRANE TRANSPORTER GTP-BINDING HOMOLOG PROBABLE Residues 76 to 148 match (7e-15) PD:PD009505 which is described as COMPLETE IRON PROTEOME FERROUS B TRANSMEMBRANE GTP-BINDING TRANSPORTER PROBABLE HOMOLOG Residues 812 to 939 match (7e-15) PD:PD072412 which is described as IRON PROTEOME COMPLETE FERROUS B TRANSMEMBRANE GTP-BINDING PROBABLE INNER MEMBRANEParalogs: Local Blast Search TDE2063 is paralogously related to TDE0083 (GTP-binding protein) (3e-05) and TDE0305 (GTP-binding protein) (4e-04).Pfam Summary: Pfam Search Residues 10 to 939 (E-value = 1.3e-144) place TDE2063 in the FeoB family which is described as Ferrous iron transport protein B (PF02421)Structural Feature(s):

`Feature Type`	`Start`	`Stop`
`transmembrane`	`297`	`314`
`transmembrane`	`319`	`338`
`transmembrane`	`371`	`388`
`transmembrane`	`431`	`455`
`transmembrane`	`514`	`531`
`transmembrane`	`536`	`560`
`transmembrane`	`605`	`622`
`transmembrane`	`888`	`905`
`transmembrane`	`919`	`936`

Top PDB Hits: No PDB hits found using the nr database and 5 rounds of Psi-BLAST (E-value < 0.01)Gene Protein Sequence: MKKEKINIAFAGQPNSGKSTLFNMMTGAHQHVANYPGITVEKKTGEYFAL DQSVFITDLPGTYSLTSYSPEERVTRNFILREKPELLVNIADASNLERHL YLTFQLLEMNCPIVMYLNKMDSAKNAGLQIDVDKVSSLLGIPIIAGSAKK KEKINELKELISKTAESSEPQKPFMLTYGKDMESYLEKIVEKLKASAKDE FFSIPLRWLAIKLCEKDSAVIEEEGKNFTNFDSILTFIKEIEAEHKEKHK HSFEIEIALARSAAAKKIVEAAVSKKELEQKAVESLNIKRKVTETIAALI LCFVTYEILDSLFLLLPIPIVANNILRLILSLAGAFAFTGGAALIYTKGG SGSINSTDRIDKVLCHKVYGLLILVELVLVFYWITVVLGYKMTDKVFPIF KFVRAIVSQLIYPEGLINEGPLRGLFLSGIIDGAIMILNYVPIFFCLFAL IAFLEDVGYMARLAFIMDRILRKFGLHGQSTLPMILSGVIMGGCVVPGVM STRTIRDDKSRLVTILILPLLNCMAKIPFYVLITGIFFTSYQWIVLGGIS FFTLIVALIVAKYFSLYVVHGKPEPFVLELPAYNMPTLRGVLTRTFERLW SFIKKVATTVVAVSVIIWAGVNFPSLSSEKTAQYEARKAAYIQDFAGKLN NSYSQYFASEKGFIEYQRLTEKLYLYDAINLFGGAKGMEKNINRLFLQNP EMTKIALKGKIELGSNIGAFKNYFDMYSSAKKDFDKAYNDAQEFQKPILK ASFYAYWQKLNPYFFALVRTGKVKISGTAVIDSEAAAAAKAIRPASADLK LISVQLRKETLENSVLGYLGKAMEPVTKYAGFDWKVNIAILGSFAAKEAL VSTLGTIYSVESSSEDSGKVLEARIQDKETGLTPLDGLTIMILIALFPPC IATVMATKTETQSVGWTLFSVMYPVVLSSLVAVLVFQLGRLFGFGene Nucleotide Sequence: Sequence Viewer ATGAAAAAAGAAAAAATAAATATTGCTTTTGCCGGTCAGCCTAACTCCGG TAAGTCAACCCTATTTAACATGATGACGGGAGCTCATCAGCATGTTGCAA ACTATCCGGGTATCACTGTTGAGAAAAAAACGGGAGAGTATTTTGCTCTT GACCAATCGGTTTTTATTACCGACTTGCCCGGCACTTACAGCCTTACTTC CTATTCACCGGAAGAGAGAGTAACCCGTAATTTTATCCTCCGTGAAAAGC CCGAACTTTTGGTAAACATTGCCGATGCCTCAAATTTGGAAAGACATCTT TATCTGACATTCCAGCTTTTGGAAATGAACTGTCCTATTGTTATGTACTT AAACAAGATGGATTCTGCAAAAAATGCAGGCTTGCAAATCGATGTTGATA AAGTTTCTTCTCTCTTGGGTATTCCGATAATAGCCGGCTCGGCCAAGAAA AAAGAAAAGATAAACGAATTAAAAGAGCTTATTTCAAAAACGGCTGAAAG CTCCGAACCGCAAAAACCCTTTATGCTTACCTACGGTAAGGATATGGAAT CCTATTTGGAAAAAATTGTCGAAAAATTAAAGGCTTCTGCAAAGGACGAA TTTTTTTCTATTCCCTTAAGATGGCTTGCAATCAAGCTTTGCGAAAAGGA CTCCGCAGTTATCGAAGAAGAGGGTAAAAATTTTACAAACTTTGATTCCA TTTTAACTTTTATAAAAGAAATTGAAGCCGAGCACAAAGAAAAACATAAG CACAGCTTTGAAATAGAAATAGCTCTTGCCCGCTCCGCTGCGGCAAAAAA AATTGTTGAAGCAGCGGTTTCAAAAAAAGAGCTTGAACAAAAAGCCGTCG AGTCCTTAAATATTAAAAGAAAGGTTACCGAGACCATTGCCGCCCTTATT CTTTGTTTTGTAACCTATGAGATTTTGGATTCCCTCTTTTTGCTTTTGCC GATTCCTATCGTTGCAAATAACATTCTACGCTTGATTCTTAGCTTAGCCG GAGCTTTTGCCTTTACGGGAGGAGCTGCTCTTATCTATACTAAAGGCGGT TCAGGCAGTATAAATTCAACCGACAGAATCGACAAGGTGCTTTGTCACAA GGTTTACGGTCTTTTGATTTTGGTTGAGCTTGTTTTGGTTTTCTATTGGA TAACGGTAGTTTTGGGTTATAAGATGACCGACAAGGTTTTCCCGATATTT AAATTTGTCAGAGCAATAGTTTCTCAACTTATTTATCCTGAAGGACTTAT AAACGAGGGCCCATTAAGAGGTTTGTTTTTAAGCGGGATAATTGATGGGG CAATAATGATTTTAAACTATGTCCCAATCTTTTTCTGCTTGTTTGCCCTC ATTGCCTTTTTGGAAGATGTCGGCTACATGGCCCGCCTTGCCTTTATCAT GGATAGGATTTTACGCAAGTTCGGTTTACACGGACAGTCAACCCTTCCTA TGATTCTCTCGGGTGTTATAATGGGAGGCTGCGTTGTTCCAGGTGTTATG TCCACAAGGACAATCAGAGATGATAAGTCAAGATTGGTAACGATTCTTAT CTTGCCCCTTCTTAACTGTATGGCAAAGATTCCTTTTTATGTTTTAATTA CGGGAATATTTTTTACAAGCTACCAATGGATAGTTCTAGGCGGAATTTCC TTTTTTACATTGATAGTCGCCCTGATTGTTGCAAAATATTTCAGCCTCTA TGTTGTTCACGGCAAGCCTGAACCCTTTGTACTTGAGCTTCCGGCTTATA ATATGCCGACCCTTAGAGGTGTTTTAACACGCACCTTTGAACGCTTATGG AGCTTTATAAAAAAAGTTGCAACGACTGTAGTTGCCGTTTCAGTTATAAT CTGGGCAGGTGTAAATTTTCCTTCTTTGAGCTCTGAAAAAACTGCTCAAT ATGAAGCAAGAAAAGCAGCTTACATTCAGGACTTTGCAGGAAAATTAAAC AATTCCTATTCCCAATATTTTGCTTCCGAAAAGGGCTTTATAGAATATCA GCGTTTAACCGAAAAGCTTTATTTGTATGATGCCATAAATCTGTTCGGCG GAGCTAAGGGCATGGAAAAGAATATAAACAGATTGTTTTTACAAAATCCC GAAATGACAAAAATTGCCTTAAAAGGAAAAATTGAACTCGGCAGTAATAT AGGTGCTTTTAAAAATTATTTTGATATGTATTCTTCCGCAAAAAAAGATT TTGATAAGGCATACAATGATGCTCAAGAATTTCAAAAGCCTATTTTAAAG GCTTCATTTTATGCTTATTGGCAAAAGCTGAATCCTTACTTCTTTGCCCT TGTCAGAACCGGAAAAGTAAAAATTTCAGGCACAGCTGTAATAGATTCCG AGGCCGCTGCCGCTGCAAAGGCTATACGCCCTGCAAGTGCGGACCTAAAG CTTATCTCCGTACAATTGCGTAAAGAAACTTTGGAGAACTCCGTTTTGGG ATACCTGGGAAAGGCAATGGAACCCGTTACAAAATATGCGGGCTTTGATT GGAAGGTAAATATCGCAATTCTAGGTTCCTTTGCCGCAAAGGAAGCTCTT GTTTCGACCTTGGGCACTATTTACAGTGTTGAGTCTTCAAGCGAGGATTC GGGTAAAGTTTTGGAAGCCCGCATTCAGGATAAGGAAACGGGATTGACCC CATTAGACGGTCTTACTATTATGATTTTGATAGCCCTTTTCCCGCCCTGT ATTGCTACCGTTATGGCAACAAAGACCGAGACTCAGAGTGTTGGCTGGAC GCTATTCAGTGTTATGTATCCCGTGGTCTTGAGCTCACTAGTTGCCGTCC TTGTTTTCCAGCTGGGAAGATTGTTCGGCTTT

Los Alamos National Laboratory • Est 1943