US 7,326,813 B2
Process for producing benzylamine derivative
Akinori Ito, Shizuoka (Japan); Hideaki Ohashi, Fujieda (Japan); and Kagetomo Magaribuchi, Shizuoka (Japan)
Assigned to Ihara Chemical Industry, Tokyo (Japan)
Appl. No. 10/540,749
PCT Filed Dec. 26, 2003, PCT No. PCT/JP03/16995
§ 371(c)(1), (2), (4) Date Jun. 24, 2005,
PCT Pub. No. WO2004/058681, PCT Pub. Date Jul. 15, 2004.
Claims priority of application No. 2002-376272 (JP), filed on Dec. 26, 2002.
Prior Publication US 2006/0155141 A1, Jul. 13, 2006
Int. Cl. C07C 209/62 (2006.01); C07C 211/29 (2006.01); C07C 231/12 (2006.01); C07C 233/31 (2006.01); C07C 269/04 (2006.01)
U.S. Cl. 564—169  [564/161] 5 Claims
 
1. A process for producing a benzylamine derivative represented by the general formula (3):

OG Complex Work Unit Drawing
wherein X1, R1 and R2 are as defined below, which comprises reacting a benzyl derivative represented by the general formula (1):

OG Complex Work Unit Drawing
wherein X1 represents a halogen atom and R1 represents an acyl group, with a haloacyl compound represented by the general formula (2):
R2—X2  (2)
wherein X2 represents a halogen atom and R2 represents an acyl group, in the presence of Lewis acid.