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Moore, M.D., and Hu, W.-S. (2009) HIV-1 RNA dimerization: It takes two to tango. AIDS Rev., in press. Russell,
R.A., Moore, M.D., Hu,
W.-S., and Pathak,
V.K. (2009) APOBEC3G induces a hypermutation gradient:
Purifying selection at multiple steps during HIV-1 replication results in levels
of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA,
and low in virion RNA. Retrovirology 6: 16 (Feb 13 Epub ahead of print). Moore,
M.D., Chin, M.P.S., and Hu, W.-S. (2009) HIV-1 recombination:
An experimental assay and a phylogenetic approach. In Prasad, V.R.,
and Kalpana, G.V. (eds.), HIV Protocols, 2nd Ed., Methods in Molecular Biology,
Vol. 485, Humana Press, pp. 87-105. Moore,
M.D., Fu, W., Soheilian, F., Nagashima, K., Ptak, R.G., Pathak, V.K., and Hu,
W.-S. (2008) Suboptimal inhibition of protease activity in human
immunodeficiency virus type 1: Effects on virion morphogenesis and RNA maturation.
Virology 379: 152-160. Chen,
J., Pathak, V.K., Peng, W., and Hu, W.-S. (2008) Capsid proteins
from human immunodeficiency virus type 1 and simian immunodeficiency virus SIVmac
can coassemble into mature cores of infectious viruses. J. Virol. 82: 8253-8261. Nikolaitchik,
O.A., Gorelick, R.J., Leavitt, M.G., Pathak, V.K., and Hu, W.-S.
(2008) Functional complementation of nucleocapsid and late domain PTAP mutants
of human immunodeficiency virus type 1 during replication. Virology 375:
539-549. Chin, M.P., Lee, S.-K., Chen, J., Nikolaitchik, O.A., Powell, D.A., Fivash, M.J., Jr., and Hu, W.-S. (2008) Long-range recombination gradient between HIV-1 subtypes B and C variants caused by sequence differences in the dimerization initiation signal region. J. Mol. Biol. 377: 1324-1333. [Abstract] [Full-text PDF article] Chukkapalli,
V., Hogue, I.B., Boyko, V., Hu, W.-S., and Ono, A. (2008) Interaction
between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate
is essential for efficient Gag-membrane binding. J. Virol. 82: 2405-2417.
Motomura, K., Chen, J., and Hu, W.-S. (2008) Genetic recombination between human immunodeficiency virus type 1 (HIV-1) and HIV-2, two distinct human lentiviruses. J. Virol. 82: 1923-1933. [Abstract] [Full-text PDF article] Chin,
M.P., Chen, J., Nikolaitchik, O.A., and Hu, W.-S. (2007) Molecular
determinants of HIV-1 intersubtype recombination potential. Virology 363:
437-446. Fu, W., Prasad, V.V.S.P., Chen, J., Nikolaitchik, O., and Hu, W.-S. (2007) Molecular mechanisms of simian immunodeficiency virus SIVagm RNA encapsidation. Virology 363: 210-219. [Abstract] [Full-text PDF article] Thomas,
D.C., Voronin, Y.A., Nikolenko, G.N., Chen, J., Hu, W.-S., and Pathak,
V.K. (2007) Determination of the ex vivo rates of human immunodeficiency
virus type 1 reverse transcription by using novel strand-specific amplification
analysis. J. Virol. 81: 4798-4807. Lee, S.K., Boyko, V., and Hu, W.-S. (2007) Capsid is an important determinant for functional complementation of murine leukemia virus and spleen necrosis virus Gag proteins. Virology 360: 388-397. [Abstract] [Full-text PDF article] Xu,
H., Chertova, E., Chen, J., Ott, D.E., Roser, J.D., Hu, W.-S., and Pathak,
V.K. (2007) Stoichiometry of the antiviral protein APOBEC3G in HIV-1
virions. Virology 360: 247-256. Moore,
M.D., Fu, W., Nikolaitchik, O., Chen, J., Ptak, R.G., and Hu, W.-S.
(2007) Dimer initiation signal of human immunodeficiency virus type 1: Its
role in partner selection during RNA copackaging and its effects on recombination.
J. Virol. 81: 4002-4011. Chen,
J., Powell, D., and Hu, W.-S. (2006) High frequency of genetic
recombination is a common feature of primate lentivirus replication. J.
Virol. 80: 9651-9658. Boyko,
V., Leavitt, M., Gorelick, R., Fu, W., Nikolaitchik, O., Pathak, V., Nagashima,
K., and Hu, W.-S. (2006) Coassembly and complementation of
Gag proteins from HIV-1 and HIV-2, two distinct human pathogens. Mol. Cell
23: 281-287. Nikolaitchik, O., Rhodes, T.D., Ott, D., and Hu, W.-S. (2006) Effects of mutations in the human immunodeficiency virus type 1 gag gene on RNA packaging and recombination. J. Virol. 80: 4691-4697. [Abstract] [Full-text PDF article] Fu,
W., Dang, Q., Nagashima, K., Freed, E.O., Pathak, V.K., and Hu, W.-S.
(2006) Effects of Gag mutation and processing on retroviral dimeric RNA
maturation. J. Virol. 80: 1242-1249. Chen,
J., Rhodes, T.D., and Hu, W.-S. (2005) Comparison of the genetic
recombination rates of human immunodeficiency virus type 1 in macrophages and
T cells. J. Virol. 79: 9337-9340. Chin,
M.P.S., Rhodes, T.D., Chen, J., Fu, W., and Hu, W.-S. (2005)
Identification of a major restriction in HIV-1 intersubtype recombination.
Proc. Natl. Acad. Sci. USA 102: 9002-9007. Lee,
S.-K., Nagashima, K., and Hu, W.-S. (2005) Cooperative effect
of Gag proteins p12 and capsid during early events of murine leukemia virus replication.
J. Virol. 79: 4159-4169. Chen, J., Dang, Q., Unutmaz, D., Pathak, V.K., Maldarelli, F., Powell, D., and Hu, W.-S. (2005) Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: Preference in virus entry is important but is not the sole factor. J. Virol. 79: 4140-4149. [Abstract] [Full-text PDF article] Rhodes,
T.D., Nikolaitchik, O., Chen, J., Powell, D., and Hu, W.-S. (2005)
Genetic recombination of human immunodeficiency virus type 1 in one round of viral
replication: Effects of genetic distance, target cells, accessory genes, and lack
of high negative interference in crossover events. J. Virol. 79: 1666-1677.
Svarovskaia,
E.S., Xu, H., Mbisa, J.L., Barr, R., Gorelick, R.J., Ono, A., Freed, E.O., Dang,
Q., Chen, J., Unutmaz, D., Coffin, J.M., Pathak, V.K., Powell, D., KewalRamani,
V.N., Maldarelli, F., and Hu, W.-S. (2004) Nonrandom HIV-1
infection and double infection via direct and cell-mediated pathways. Proc.
Natl. Acad. Sci. USA 101: 632-637. Rhodes,
T.D., Wargo, H.L., and Hu, W.-S. (2003) High rates of human
immunodeficiency virus type 1 recombination: Near-random segregation of markers
one kilobase apart in one round of viral replication. J. Virol. 77: 11193-11200. Cheslock, S.R., Poon, D.T.K., Fu, W., Rhodes, T.D., Henderson, L.E., Nagashima, K., McGrath, C.F., and Hu, W.-S. (2003) Charged assembly helix motif in murine leukemia virus capsid: An important region for virus assembly and particle size determination. J. Virol. 77: 7058-7066. [Abstract] [Full-text PDF article] Fu,
W., and Hu, W.-S. (2003) Functional replacement of nucleocapsid
flanking regions by heterologous counterparts with divergent primary sequences:
Effects of chimeric nucleocapsid on the retroviral replication cycle. J. Virol.
77: 754-761. Hu, W.-S., Rhodes, T., Dang, Q., and Pathak, V.K. (2003) Retroviral recombination: Review of genetic analyses. Front. Biosci. 8: D143-D155. [Abstract] [Full-text HTML article] Svarovskaia, E.S., Cheslock, S.R., Zhang, W.-H., Hu, W.-S., and Pathak, V.K. (2003) Retroviral mutation rates and reverse transcriptase fidelity. Front. Biosci. 8: D117-D134. [Abstract] [Full-text HTML article] Zhang, W.-H., Hwang, C.K., Hu, W.-S., Gorelick, R.J., and V.K. Pathak. (2002) Zinc finger domain of murine leukemia virus nucleocapsid protein enhances the rate of viral DNA synthesis in vivo. J. Virol. 76: 7473-7484. [Abstract] [Full-text PDF article] Beasley,
B.E., and Hu, W.-S. (2002) cis-Acting elements important for retroviral
RNA packaging specificity. J. Virol. 76: 4950-4960. Dang,
Q., and Hu, W.-S. (2001) Effects of homology length in the repeat region
on minus-strand DNA transfer and retroviral replication. J. Virol. 75: 809-820. Hu, W.-S., and Pathak, V.K. (2000) Design of retroviral vectors and helper cells for gene therapy. Pharmacol. Rev. 52: 493-511. [Abstract] [Full-text PDF article] Cheslock, S.R., Andersen, J.A., Hwang, C.K., Pathak, V.K., and Hu, W.-S. (2000) Utilization of nonviral sequences for minus-strand DNA transfer and gene reconstitution during retroviral replication. J. Virol. 74: 9571-9579. [Abstract] [Full-text PDF article] Anderson, J.A., Pathak, V.K., and Hu, W.-S. (2000) Effect of the murine leukemia virus extended packaging signal on the rates and locations of retroviral recombination. J. Virol. 74: 6953-6963. [Abstract] [Full-text PDF article] Certo,
J.L., Kabdulov, T.O., Paulson, M.L., Anderson, J.A., and Hu, W.-S. (1999)
The nucleocapsid domain is responsible for the ability of spleen necrosis virus
(SNV) gag polyprotein to package both SNV and murine leukemia virus RNA. J. Virol.
73: 9170-9177. Certo, J.L., Shook, B.F., Yin, P.D., Snider, J.T., and Hu, W.-S. (1998) Nonreciprocal pseudotyping: murine leukemia virus proteins cannot efficiently package spleen necrosis virus-based vector RNA. J. Virol. 72: 5408-5413. [Abstract] [Full-text PDF article] Anderson, J.A., Bowman, E.H., and Hu, W.-S. (1998) Retroviral recombination rates do not increase linearly with marker distance and are limited by the size of the recombining subpopulation. J. Virol. 72: 1195-1202. [Abstract] [Full-text PDF article] Anderson,
J.A., Teufel, R.J. 2nd, Yin, P.D., and Hu, W.-S. (1998) Correlated template-switching
events during minus-strand DNA synthesis: a mechanism for high negative interference
during retroviral recombination. J. Virol. 72: 1186-1194. Yin,
P.D., and Hu, W.-S. (1997) RNAs from genetically distinct retroviruses
can copackage and exchange genetic information in vivo. J. Virol. 71: 6237-6242. Yin,
P.D., Pathak, V.K., Rowan, A.E., Teufel, R.J. 2nd, and Hu, W.-S. (1997)
Utilization of nonhomologous minus-strand DNA transfer to generate recombinant
retroviruses. J. Virol. 71: 2487-2494. [Abstract] [Full-text
PDF article] Last modified: 18 February 2009 | ... |
