GRISARU-SOEN G, ABARAHAMI A, PASSWELL JH, LUSKY A, KELLER N, LERNER-GEVA L; Interscience Conference on Antimicrobial Agents and Chemotherapy (43rd: 2003: Chicago, Ill.).

Abstr Intersci Conf Antimicrob Agents Chemother Intersci Conf Antimicrob Agents Chemother. 2003 Sep 14-17; 43: abstract no. G-1548.

Safra Children Hospital, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.

BACKGROUND: To identify the prevalence and the spectrum of clinical presentation of rotavirus as compared to other pathogens among children hospitalized with gastroenteritis. METHODS: A retrospective review of hospitalization records and laboratory results of all children aged 0-5 years that were hospitalized at the Chaim Sheba Medical Center, Israel between September 1999 and August 2001, with a diagnosis of acute gastroenteritis. The medical records of all the patients with Rotavirus and a random sample of patients with other pathogens were abstracted. The abstracted data included demographic information, presenting signs and symptoms, severity of disease, degree of dehydration, treatment and length of hospitalization, in addition to the specific pathogen that was presented in the stool cultures. RESULTS: During the study period 1064 children were hospitalized with acute gastroenteritis. Rotavirus was identified by antigen detection using ELISA method in the stool of 126 children (12%). The mean age at admission was 1.16+/-0.77 years for Rotavirus as compared to 1.5+/-1.23 years for the other pathogens (p=0.03). The length of the IV fluid treatment was 2.57+/-1.68 days for Rotavirus as compared to 1.82+/-1.04 days (p=0.01) for the other pathogens. The length of hospitalization was 4.36+/-5.58 days for Rotavirus as compared to 2.47+/-1.56 days for the other pathogens (p=0.01). More cases of Rotavirus infection were acquired nosocomially (11.29%) as compared to the other pathogens (5.26%) although did not reach statistical significance. CONCLUSIONS: Rotavirus gastroenteritis is associated with younger age and more severe morbidity compared to other pathogens as reflected by longer period of IV fluid treatment and longer length of hospitalization.

Publication Types:

• Meeting Abstracts

Keywords:

• Acute Disease
• Adenovirus Infections, Human
• Child
• Dehydration
• Feces
• Gastritis
• Gastroenteritis
• Hospitalization
• Humans
• Inflammatory Bowel Diseases
• Israel
• Rotavirus
• Rotavirus Infections

Other ID:

• GWAIDS0026336

UI: 102265960

From Meeting Abstracts