CONDITION	STATUS	TRIAL TITLE	INTERVENTIONS	SPONSOR	PHASE	SIZE	FUNDED BY	STUDY TYPE	STUDY DESIGN	NCT ID	OTHER IDS	START DATE	COMPLETION DATE
Partial Epilepsies	Active, not recruiting	To Determine Tolerability and Efficacy of Long-Term Oral Lacosamide in Patients With Partial Seizures	Drug lacosamide	UCB	Phase II	500	INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Uncontrolled; Single Group Assignment; Safety/Efficacy Study	NCT00552305	SP615	Aug-01	Oct-08
Epilepsy	Completed	SPM 927 (400mg/Day and 600mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization	Drug SPM 927	UCB	Phase III	400	INDUSTRY	Interventional	Treatment; Randomized; Double-Blind; Placebo Control; Parallel Assignment; Safety/Efficacy Study	NCT00136019	SP754	Mar-04	Aug-06
Partial Seizures With or Without Secondary Generalization	Completed	A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel Group Trial to Investigate the Efficacy and Safety of SPM 927 (200mg/Day and 400mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization	Drug SPM 927	UCB	Phase III		INDUSTRY	Interventional	Treatment; Randomized; Double-Blind; Placebo Control; Parallel Assignment	NCT00220415	SP755	May-04	Jan-06
Partial Epilepsies	Active, not recruiting	Determine Safety and Efficacy of Long-Term Oral Lacosamide in Patients With Partial Seizures	Drug lacosamide	UCB	Phase III	308	INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Uncontrolled; Single Group Assignment; Safety/Efficacy Study	NCT00522275	SP756	Oct-04	Apr-10
Epilepsy	Active, not recruiting	Assess Safety and Efficacy of Lacosamide in Patients With Partial Seizures	Drug Lacosamide	UCB	Phase III	376	INDUSTRY	Interventional	Treatment; Open Label; Uncontrolled; Single Group Assignment; Safety/Efficacy Study	NCT00515619	SP774	Dec-04	Oct-08
Epilepsies, Partial	Completed	Safety and Tolerability of Intravenous SPM 927 as Replacement for Oral SPM 927 in Subjects With Partial Seizures	Drug SPM 927	UCB	Phase II / Phase III	160	INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Dose Comparison; Single Group Assignment	NCT00151879	SP757	Feb-05	May-06
Epilepsy	Recruiting	Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-Onset Seizures	Drug lacosamide; Drug lacosamide	UCB	Phase III	357	INDUSTRY	Interventional	Treatment; Randomized; Double Blind (Subject, Caregiver, Investigator); Parallel Assignment; Safety/Efficacy Study	NCT00520741	SP902	Aug-07	Oct-09
Epilepsy	Enrolling by invitation	Trial to Assess Long-Term Lacosamide (LCM) Monotherapy Use and Safety of LCM Monotherapy and Adjunctive Therapy for Partial-Onset Seizures	Drug Lacosamide	UCB	Phase III	225	INDUSTRY	Interventional	Treatment; Open Label; Single Group Assignment; Safety/Efficacy Study	NCT00530855	SP904	Jan-08	Dec-10
Partial Epilepsies	Recruiting	Trial to Assess the Safety of a Single Dose of iv Lacosamide Followed by Twice Daily Oral Lacosamide in Patients With Partial-Onset Seizures	Drug Lacosamide	UCB	Phase III	100			Treatment; Non-Randomized; Open Label; Single Group Assignment; Safety╩Study	NCT00655551	SP925	Mar-08	Sep-09
Partial Epilepsies	Recruiting	Trial to Assess the Long-Term Safety of Oral Lacosamide in Patients With Partial-Onset Seizures	Drug Lacosamide	UCB	Phase III	100			Treatment; Non-Randomized; Open Label; Single Group Assignment; Safety Study	NCT00655486	SP926	Apr-08	Apr-10
Fibromyalgia Syndrome	Completed	A Trial to Assess Lacosamide in Subjects With Signs and Symptoms Associated With Fibromyalgia Syndrome	Drug Lacosamide; Other placebo	UCB	Phase II	416	INDUSTRY	Interventional	Treatment; Randomized; Double Blind (Subject, Investigator); Placebo Control; Parallel Assignment; Safety/Efficacy Study	NCT00401830	SP887	Oct-06	Feb-08
Migraine Disorders	Active, not recruiting	A Trial of Lacosamide for Migraine Prophylaxis	Drug Lacosamide; Other Placebo; Drug Lacosamide	UCB	Phase II	192	INDUSTRY	Interventional	Treatment; Randomized; Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor); Placebo Control; Parallel Assignment; Safety/Efficacy Study	NCT00440518	SP906	Feb-07	Jul-08
Postherpetic Neuralgia	Completed	An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)	Drug SPM 927	UCB	Phase II		INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Uncontrolled; Single Group Assignment	NCT00238511	SP690	Nov-02	Jan-05
Chronic Refractory Neuropathic Pain	Active, not recruiting	A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy	Drug Lacosamide	UCB	Phase II	7	INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Uncontrolled; Single Group Assignment; Safety/Efficacy Study	NCT00237458	SP647	May-01	Dec-08
Diabetic Neuropathy	Completed	A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic Neuropathy	Drug SPM 927	UCB	Phase III	357	INDUSTRY	Interventional	Treatment; Randomized; Double-Blind; Placebo Control; Parallel Assignment; Safety/Efficacy Study	NCT00238524	SP743	Dec-03	Jan-05
Diabetic Neuropathy	Completed	A Trial to Assess the Efficacy and Safety of SPM 927 in Subjects With Painful Distal Diabetic Neuropathy	Drug SPM 927	UCB	Phase II / Phase III	496	INDUSTRY	Interventional	Treatment; Randomized; Double-Blind; Placebo Control; Parallel Assignment	NCT00235469	SP742	Apr-04	Jun-05
Painful Diabetic Neuropathy	Active, not recruiting	Open-Label, Follow-on Trial to Assess the Long-Term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.	Drug Lacosamide	UCB	Phase III	614	INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Uncontrolled; Single Group Assignment; Safety Study	NCT00546351	SP746, Eudra CT-No., 2004-000551-42	May-04	Dec-08
Diabetic Neuropathy	Active, not recruiting	A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy	Drug lacosamide	UCB	Phase II / Phase III	452	INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Uncontrolled; Single Group Assignment; Safety/Efficacy Study	NCT00235443	SP745	Sep-04	Sep-08
Diabetic Neuropathies	Completed	Trial to Assess the Efficacy and Safety of SPM 927 (200, 400, and 600mg/Day) in Subjects With Painful Distal Diabetic Neuropathy	Drug SPM 927	UCB	Phase III	654	INDUSTRY	Interventional	Treatment; Randomized; Double-Blind; Placebo Control; Parallel Assignment; Safety/Efficacy Study	NCT00135109	SP768	Oct-04	Dec-05
Painful Diabetic Neuropathy	Completed	A Trial to Assess the Long-Term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic Neuropathy	Drug lacosamide	UCB	Phase III	371	INDUSTRY	Interventional	Treatment; Non-Randomized; Open Label; Uncontrolled; Single Group Assignment	NCT00220337	SP830	Dec-04	Oct-07
Painful Diabetic Neuropathy	Completed	A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy	Drug SPM 929	UCB	Phase III	537	INDUSTRY	Interventional	Treatment; Randomized; Double-Blind; Placebo Control; Parallel Assignment; Safety/Efficacy Study	NCT00350103	SP874	Jun-06	Jun-07