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Title Radionuclide transit in esophageal varices
Creator/Author Yeh, S.H. ; Wang, S.J. ; Wu, L.C. ; Liu, R.S. ; Tsai, Y.T. ; Chiang, T.T.
Publication Date1985 May 01
OSTI IdentifierOSTI ID: 5961800
Report Number(s)CONF-850611-
Other Number(s)CODEN: JNMEA
Resource TypeConference
Specific TypeJournal Article
Resource RelationJ. Nucl. Med. ; Vol/Issue: 26:5; 32. annual meeting of the Society of Nuclear Medicine; 2 Jun 1985; Houston, TX, USA
Research OrgVeterans General Hospital
Subject550601 -- Medicine-- Unsealed Radionuclides in Diagnostics ;560160 -- Radionuclide Effects, Kinetics, & Toxicology; ESOPHAGUS-- DYNAMIC FUNCTION STUDIES;ESOPHAGUS-- SCINTISCANNING;TECHNETIUM 99-- TISSUE DISTRIBUTION;TECHNETIUM 99-- UPTAKE; CHEST;GAMMA CAMERAS;IMAGE PROCESSING;INGESTION;OPTIMIZATION;ORAL ADMINISTRATION;PATIENTS;RADIOISOTOPE SCANNING;SENSITIVITY
Related SubjectBETA DECAY RADIOISOTOPES;BETA-MINUS DECAY RADIOISOTOPES;BODY;BODY AREAS;CAMERAS;COUNTING TECHNIQUES;DIAGNOSTIC TECHNIQUES;DIGESTIVE SYSTEM;DISTRIBUTION;HOURS LIVING RADIOISOTOPES;INTAKE;INTERMEDIATE MASS NUCLEI;ISOMERIC TRANSITION ISOTOPES;ISOTOPES;NUCLEI;ODD-EVEN NUCLEI;ORGANS;PROCESSING;RADIOISOTOPE SCANNING;RADIOISOTOPES;TECHNETIUM ISOTOPES;YEARS LIVING RADIOISOTOPES
Description/Abstract This study assessed esophageal motility in patients with esophageal varices by radionuclide transit studies.^ Data were acquired in list mode after an oral dose of 0.5 mCi Tc-99m sulfur colloid in 10 ml of water in the supine position above a low-energy all-purpose collimator of a gamma camera.^ The condensed image (CI) superimposed with a centroid curve was also produced in each case.^ Twenty-five normal subjects (N) and 32 patients (pts) with esophageal varices by endoscopy (large varices in Grades IV and V in 8 and small varices in Grade III or less in 24) were studied.^ TMTT, RTT, RF, and RI were all significantly increased in pts as compared to N.^ Especially, the transit time for the middle third (6.7 +- 2.6 sec vs 3.5 +- 0.9 sec in N, rho < 0.005) had the optimal sensitivy and specificity of 88% each at the cutoff value of 4.2 sec as determined by ROC analysis.^In summary, radionuclide transit disorders occur in the majority of pts with esopageal varices.^ The middle RTT and CI are both optimal in sensitivity and specificity for detecting the abnormalities.
Country of PublicationUnited States
LanguageEnglish
FormatPages: 93
System Entry Date2001 May 13

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