US 7,371,845 B2
	MAGE-A3 peptides presented by HLA class II molecules
Yi Zhang, Brussels (Belgium); Pascal Chaux, Thurey (France); Thierry Boon-Falleur, Brussels (Belgium); and Pierre Van Der Bruggen, Brussels (Belgium)
Assigned to Ludwig Institute for Cancer Research, New York, N.Y. (US)
Filed on May 23, 2006, as Appl. No. 11/439,334.
Application 11/439334 is a division of application No. 09/860840, filed on May 18, 2001, granted, now 7,049,413.
Prior Publication US 2006/0211091 A1, Sep. 21, 2006
Int. Cl. C07H 21/04 (2006.01); C12N 15/00 (2006.01); C12N 5/02 (2006.01)

U.S. Cl. 536—23.5  [435/325; 435/320.1]

20 Claims

1. An isolated nucleic acid encoding a MAGE-A3 HLA class II-binding peptide that consists of a fragment of SEQ ID NO:2, wherein the fragment comprises an amino acid sequence selected from the group consisting of SEQ ID NO:3, SEQ ID NO:4 and SEQ ID NO:7, wherein the MAGE-A3 HLA class II binding peptide includes up to 7 amino acids of SEQ ID NO:2 consecutive to the N-terminus and/or the C-terminus of SEQ ID NOs:3, 4 or 7.